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Author: Nature Biotechnology

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Nature Biotechnology's Forum podcast explores biotech's latest scientific publications, found in Nature Biotechnology and elsewhere, through discussions with today's leading researchers.

Hosted on Acast. See acast.com/privacy for more information.

24 Episodes
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In this episode, our Associate Editor Cláudia Vilhena talks with three authors of the method Starfysh, a computational toolbox combining spatial transcriptomics and histology data.During their chat, Siyu, Yinou and Lingling, all at different stages of their academic path, dig into the layers of Starfysh and its relevance for cancer research. They also share the struggles of peer review, the wonders of collaborative work and how this experience shaped their, sure-to-be fantastic, academic careers. Hosted on Acast. See acast.com/privacy for more information.
On our very first episode of the new podcast series from Nature Biotechnology, our Associate Editor Cláudia Vilhena interviews Marcus Walker, first author of a fantastic story on engineered bacteria used to stain textiles.With an informal and honest touch, Marcus and Cláudia dive into the behind the scenes of the paper. From the inspiration to combine microbiology and fashion, passing by what went wrong at the bench, all the way to the economical and environmental implications of living biomaterials.For all those who struggle with measuring optical density, this episode is for you! Hosted on Acast. See acast.com/privacy for more information.
For our special Focus Issue, Chief Editor Barbara Cheifet talks with Charlotte Deane and Gevorg Grigoryan about applying new machine learning methods to protein structure prediction and protein design. We discuss exciting new technologies and their current and future clinical applications. Hosted on Acast. See acast.com/privacy for more information.
Microscopy methods today are enabling researchers to see small details within cells, previously undetectable by light microscopy. Chief Editor Barbara Cheifet speaks with Drs. Ed Boyden and Johann Danzl about the technological advances and challenges in the fields of super resolution and expansion microscopy. Hosted on Acast. See acast.com/privacy for more information.
Single-cell metabolomics is focused on detecting, understanding, and interpreting metabolites and lipids at single-cell resolution. Theodore Alexandrov and Anne Le discuss recent technical advances in the field with Chief Editor Barbara Cheifet. Hosted on Acast. See acast.com/privacy for more information.
Chief Editor Barbara Cheifet speaks with Drs. Michael Fischbach and Sarkis Mazmanian about recent work uncovering functional roles for our microbiomes and what is needed to bring microbiome therapies to the clinic.  Hosted on Acast. See acast.com/privacy for more information.
Jayme Locke and Megan Sykes discuss advances in xenotransplantation with Chief Editor Barbara Cheifet, including details of the recent transplants of pig heart and kidney into braindead patients, as well as the questions researchers and clinicians are asking next.  Hosted on Acast. See acast.com/privacy for more information.
Aviv Regev and Sarah Teichmann talk with Senior Editor Barbara Cheifet about the development and exciting recent progress of the Human Cell Atlas project. Hosted on Acast. See acast.com/privacy for more information.
Senior Editor Markus Elsner has a discussion with Ray Deshaies and Carolyn Bertozzi about PROTACs, small molecules that have the potential to treat previously-undruggable targets in clinical applications. Hosted on Acast. See acast.com/privacy for more information.
Ana Pombo and Jennifer Phillips-Cremins talk with senior editor Barbara Cheifet about how new methods to look at the 3D genome are providing insights into the links between genome structure and cellular function. Hosted on Acast. See acast.com/privacy for more information.
Kimberly Stegmaier and John Doench speak with senior editor Markus Elsner about the history and latest developments in the field of CRISPR screening.  Hosted on Acast. See acast.com/privacy for more information.
Kathryn Whitehead and Robert Langer talk with Senior Editor Markus Elsner about drug delivery methods and their applications within a wide range of therapeutic modalities.  Hosted on Acast. See acast.com/privacy for more information.
Katherine High and Donald Kohn speak with senior editor Markus Elsner about the latest developments in gene therapy Hosted on Acast. See acast.com/privacy for more information.
Stan Crooke is born ⬩ A tenuous existence ⬩ Life with his mother ⬩ The Tech Corner ⬩ Arsenal Tech High School ⬩ Nancy ⬩ Hoodlum ways ⬩ Off to Purdue Hosted on Acast. See acast.com/privacy for more information.
Karl Deisseroth and Viviana Gradinaru speak with senior editor Markus Elsner about the current state of optogenetics and how it can be used to better understand and treat human disease.  Hosted on Acast. See acast.com/privacy for more information.
Lillian Siu and Elaine Mardis speak with senior editor Markus Elsner about the current state of precision cancer medicine and what progress the future might hold. Hosted on Acast. See acast.com/privacy for more information.
The T cell wars

The T cell wars

2020-11-2429:01

Nature Biotechnology’s Irene Jarchum speaks with Michel Sadelain about off-the-shelf CAR-T cells, and discusses a recent paper from Maksim Mamonkin’s group describing a clever strategy to mitigate CAR-T cell rejection. The paper was published in Nature Biotechnology and can be read here. Hosted on Acast. See acast.com/privacy for more information.
David Liu and Jennifer Doudna talk with our Senior Editor Markus Elsner about the state of the genome editing field and what challenges remain, especially as various therapies are now entering the clinic. This episode is part of Nature Biotechnology’s Focus issue on CRISPR tools and therapies. Hosted on Acast. See acast.com/privacy for more information.
A recent Nature Biotechnology paper from Tony Atala and colleagues at Wake Forest describes the use of bioengineered scaffolds to repair substantial injuries to rabbit uteri, supporting pregnancies and live births. Senior Editor Irene Jarchum discusses this work with Mats Brännström and Mats Hellström, both from Gothenburg University in Sweden. You can read the paper here.  Hosted on Acast. See acast.com/privacy for more information.
David Shapiro Ilan talks to Senior Editor Susan Jones about a paper in the May issue where Ricardo Machado and colleagues describe how bacterial symbionts of nematodes are evolved to help these worms kill a devastating crop pest: Western Corn Rootworm. The paper can be read here. Hosted on Acast. See acast.com/privacy for more information.
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