"Second Opinion" with Christina Farr, Ash Zenooz MD & Luba Greenwood JD

In this episode of Second Opinion, Christina Farr and Luba Greenwood chat with Mike Desjadon, CEO of Anomaly Health, about the state of American healthcare heading into 2025. Mike breaks down how health insurance companies actually make money and explains why we spend $500 billion just processing medical bills. They discuss the security concerns around J.P. Morgan Healthcare Conference after a tumultuous 2024, explore why pharma companies really aren't making money from vaccines, and unpack how Ozempic transformed endocrinology from an overlooked specialty to the most coveted medical fellowship in the country. The conversation wraps with realistic predictions for healthcare in 2025. Thanks to our sponsor, Midi Health. — 📰 Be notified early when Turpentine drops new publication: https://www.turpentine.co/exclusiveaccess  🙏 Help shape our show by taking our quick listener survey at https://bit.ly/TurpentinePulse  — SPONSOR:  👩‍⚕️ Hot flashes, insomnia, brain fog? You don't have to accept these as just another part of aging. Midi Health is the virtual care clinic for women navigating midlife hormonal transition, offering FDA-approved medications, supplements and lifestyle coaching - all covered by insurance. Visit joinmidi.com to book your virtual visit today. — RECOMMENDED PODCAST: Check out Modern Relationships, where Erik Torenberg interviews tech power couples and leading thinkers to explore how ambitious people actually make partnerships work. Founders Fund's Delian Asparouhov and researcher Nadia Asparouhova kick off the series with an unfiltered conversation about their relationship evolution. Apple: https://podcasts.apple.com/us/podcast/id1786227593 Spotify: https://open.spotify.com/show/5hJzs0gDg6lRT6r10mdpVg YouTube: https://www.youtube.com/@ModernRelationshipsPod — LINKS:  Anomaly: https://www.findanomaly.com/ Subscribe to Second Opinion Newsletter: https://secondopinion.media/  — FOLLOW: https://www.linkedin.com/in/mike-desjadon-4a0a21a/ https://www.linkedin.com/in/christinafarr/ https://www.linkedin.com/in/lubagreenwood/ https://www.linkedin.com/in/ashzenooz/ — HIGHLIGHTS FROM THE EPISODE: 2024 was marked by several major healthcare events including a massive Change Healthcare cybersecurity breach, increased PBM scrutiny, Trump's election, and the tragic shooting of UnitedHealthcare CEO Brian Thompson. While security concerns exist for the upcoming JP Morgan Healthcare Conference, high hotel costs remain the primary deterrent for attendees, with many companies opting for nearby meetings instead of conference attendance. The Change Healthcare hack exposed a critical transparency issue when Americans learned that a single company had access to half of the nation's health data. The U.S. healthcare system spends $4 trillion annually, with $500 billion going to administrative costs in a complex third-party payment system where insurance companies operate on 4-6% margins and health systems on 0-4% margins. While the U.S. healthcare system is more expensive and less efficient than other countries', it offers advantages like shorter wait times and fewer age-based restrictions on procedures. The pharmaceutical industry faces significant challenges in drug development, with high failure rates and complex manufacturing processes for modern drugs, while vaccines typically don't generate major profits. For 2025, industry experts predict an increase in biotech IPOs, expansion of Medicare Advantage, potential separation of PBMs from vertically integrated entities, and greater scrutiny of PBM relationships by employers. The healthcare industry needs better transparency in pricing and in insurance plan coverage. The system incentivizes volume-based care rather than preventive care, which is evident in both payment structures and professional specialization trends. The rise of GLP-1 drugs has transformed endocrinology from one of the least desired medical specialties to the most coveted fellowship program.

Ash Zenooz and Luba Greenwood interview Andrea Ippolito about her extensive career in healthcare spanning academia, government, and the private sector, as well as her current role as founder and CEO of SimpliFed. They discuss the intricacies of government roles, the importance of women's health, and the evolving landscape of maternal health care and entrepreneurship. For full show notes, visit: https://highlightai.com/share/2c96255c-b8e5-4469-855f-dc5c22f6a339 — 📰 Be notified early when Turpentine drops new publication: https://www.turpentine.co/exclusiveaccess  🙏 Help shape our show by taking our quick listener survey at https://bit.ly/TurpentinePulse  — RECOMMENDED PODCAST: Check out Modern Relationships, where Erik Torenberg interviews tech power couples and leading thinkers to explore how ambitious people actually make partnerships work. Founders Fund's Delian Asparouhov and researcher Nadia Asparouhova kick off the series with an unfiltered conversation about their relationship evolution. Apple: https://podcasts.apple.com/us/podcast/id1786227593 Spotify: https://open.spotify.com/show/5hJzs0gDg6lRT6r10mdpVg YouTube: https://www.youtube.com/@ModernRelationshipsPod — SPONSORS: 👩‍⚕️ Hot flashes, insomnia, brain fog? You don't have to accept these as just another part of aging. Midi Health is the virtual care clinic for women navigating midlife hormonal transition, offering FDA-approved medications, supplements and lifestyle coaching - all covered by insurance. Visit joinmidi.com to book your virtual visit today. — LINKS:  SimpliFed: https://www.simplifed.com/ Subscribe to Second Opinion Newsletter: https://secondopinion.media/  — FOLLOW: https://www.linkedin.com/in/andreakippolito  https://www.linkedin.com/in/christinafarr/ https://www.linkedin.com/in/lubagreenwood/ https://www.linkedin.com/in/ashzenooz/ — TIMESTAMPS: (00:00) Intro (02:04) Andrea's government experience (02:41) Impact of political transitions (03:25) Challenges and opportunities in women's health (10:52) SimpliFed: A journey in women's health (14:12) Scaling SimpliFed (16:43) Fundraising in women's health (20:55) The future of women's health (23:09) Impact of abortion regulations on valuations (23:56) Trends in fertility and IVF (24:22) High-risk conditions in maternal health (25:14) Veterans' healthcare benefits (26:20) Advocating for change through Congress (29:53) Drug pricing and international policies (39:37) Encouraging innovation in women's health (41:11) The Debrief

Luba Greenwood and Ash Zenooz discuss the evolving biotech landscape, the impact of AI on drug discovery, the importance of using real-world evidence in drug development, and personal motivations for continuing efforts in the biotech field. For full show notes, visit: https://highlightai.com/share/f4d42739-65df-42d9-a6b4-6c1327705d7a  — 📰Be notified early when Turpentine drops new publication: https://www.turpentine.co/exclusiveaccess   — RECOMMENDED PODCAST: Check out Modern Relationships, where Erik Torenberg interviews tech power couples and leading thinkers to explore how ambitious people actually make partnerships work. Founders Fund's Delian Asparouhov and researcher Nadia Asparouhova kick off the series with an unfiltered conversation about their relationship evolution. Apple: https://podcasts.apple.com/us/podcast/id1786227593 Spotify: https://open.spotify.com/show/5hJzs0gDg6lRT6r10mdpVg YouTube: https://www.youtube.com/@ModernRelationshipsPod — SPONSORS: 👩‍⚕️ Hot flashes, insomnia, brain fog? You don't have to accept these as just another part of aging. Midi Health is the virtual care clinic for women navigating midlife hormonal transition, offering FDA-approved medications, supplements and lifestyle coaching - all covered by insurance. Visit joinmidi.com to book your virtual visit today. 📝 Notion offers powerful workflow and automation templates, perfect for streamlining processes and laying the groundwork for AI-driven automation. With Notion AI, you can search across thousands of documents from various platforms, generating highly relevant analysis and content tailored just for you - try it for free at notion.com/upstreampod 🕵️‍♂️ Take your personal data back with Incogni! Use code ECON102 at the link below and get 60% off an annual plan: https://incogni.com/econ102 — LINKS: Gallup Oncology: https://www.galloponcology.com/ PureTech Health: https://www.puretechhealth.com/  — FOLLOW: https://www.linkedin.com/in/christinafarr/  https://www.linkedin.com/in/lubagreenwood/  https://www.linkedin.com/in/ashzenooz/

Christina Farr, Ash Zenooz, and Luba Greenwood are joined by Zeke Emanuel, a prominent oncologist, bioethicist, and influential voice in healthcare to discuss the impact of GLP-1 drugs, healthcare affordability, Trump's appointments, and AI in medicine. The second half of the episode was recorded a week after Trump's election victory. For full show notes, visit: https://highlightai.com/share/dd71470c-2a01-4cfa-a011-5597a86efdf5 — 🙏 Help shape our show by taking our quick listener survey at https://bit.ly/TurpentinePulse. — RECOMMENDED PODCAST: Unpack Pricing Dive into the dark arts of SaaS pricing with Metronome CEO Scott Woody and tech leaders. Learn how strategic pricing drives explosive revenue growth in today's biggest companies like Snowflake, Cockroach Labs, Dropbox and more. Apple: https://podcasts.apple.com/us/podcast/id1765716600 Spotify: https://open.spotify.com/show/38DK3W1Fq1xxQalhDSueFg — SPONSORS: 👩‍⚕️ Hot flashes, insomnia, brain fog? You don't have to accept these as just another part of aging. Midi Health is the virtual care clinic for women navigating midlife hormonal transition, offering FDA-approved medications, supplements and lifestyle coaching - all covered by insurance. Visit joinmidi.com to book your virtual visit today. 📝Notion offers powerful workflow and automation templates, perfect for streamlining processes and laying the groundwork for AI-driven automation. With Notion AI, you can search across thousands of documents from various platforms, generating highly relevant analysis and content tailored just for you - try it for free at notion.com/upstreampod — FOLLOW: https://www.linkedin.com/in/zeke-emanuel-6ab78a1b0/ https://www.linkedin.com/in/christinafarr/ https://www.linkedin.com/in/lubagreenwood/ https://www.linkedin.com/in/ashzenooz/

Christina Farr and Ash Zenooz discuss the recent departures of prominent female CEOs from major healthcare companies and explore why progress in female leadership representation has been challenging in the healthcare industry. For full show notes, visit: https://highlightai.com/share/f0e550de-d7d5-49bd-96ea-700dde222ccc  — 📰 Be notified early when Turpentine drops new publication: https://www.turpentine.co/exclusiveaccess   — RECOMMENDED PODCAST: 🎙️ Unpack Pricing - Dive into the dark arts of SaaS pricing with Metronome CEO Scott Woody and tech leaders. Learn how strategic pricing drives explosive revenue growth in today's biggest companies like Snowflake, Cockroach Labs, Dropbox and more. Apple: https://podcasts.apple.com/us/podcast/id1765716600 Spotify: https://open.spotify.com/show/38DK3W1Fq1xxQalhDSueFg — SPONSORS: 👩‍⚕️ Hot flashes, insomnia, brain fog? You don't have to accept these as just another part of aging. Midi Health is the virtual care clinic for women navigating midlife hormonal transition, offering FDA-approved medications, supplements and lifestyle coaching - all covered by insurance. Visit joinmidi.com to book your virtual visit today. __ LINKS: HLTH: https://www.hlth.com/  — FOLLOW: https://www.linkedin.com/in/christinafarr/ https://www.linkedin.com/in/lubagreenwood/ https://www.linkedin.com/in/ashzenooz/

In this episode of Second Opinion, hosts Christina Farr, Ash Zenooz, and Luba Greenwood interview Rob Perez, founder of Life Science Cares, about his work bridging the biotech industry with poverty alleviation efforts. For full show notes, visit: https://highlightai.com/share/f3eb77b0-b71c-40fe-817e-bd3c1b4dc5b4  — RECOMMENDED PODCAST: 🎙️ Unpack Pricing - Dive into the dark arts of SaaS pricing with Metronome CEO Scott Woody and tech leaders. Learn how strategic pricing drives explosive revenue growth in today's biggest companies like Snowflake, Cockroach Labs, Dropbox and more. Apple: https://podcasts.apple.com/us/podcast/id1765716600 Spotify: https://open.spotify.com/show/38DK3W1Fq1xxQalhDSueFg __ SPONSOR: 👩‍⚕️ Hot flashes, insomnia, brain fog? You don't have to accept these as just another part of aging. Midi Health is the virtual care clinic for women navigating midlife hormonal transition, offering FDA-approved medications, supplements and lifestyle coaching - all covered by insurance. Visit joinmidi.com to book your virtual visit today. __ LINKS: Life Science Cares: https://lifesciencecares.org/ Project OnRamp: https://lifesciencecares.org/project-onramp/ Subscribe to Second Opinion Newsletter: https://secondopinion.media/  — FOLLOW: https://www.linkedin.com/in/rob-perez-93707916/  https://www.linkedin.com/in/christinafarr/ https://www.linkedin.com/in/lubagreenwood/ https://www.linkedin.com/in/ashzenooz/

Dr. Lloyd Minor, Dean of Stanford School of Medicine joins Christina Farr, Ash Zenooz, and Luba Greenwood to discuss the various transformative advancements and challenges in healthcare, focusing on the equitable use of AI and technology to enhance patient care, improve medical training, and address labor shortages. They dive into AI’s role in imaging, pathology, and electronic health records, as well as innovative approaches in medical education.  — SPONSOR: 👩‍⚕️ Hot flashes, insomnia, brain fog? You don't have to accept these as just another part of aging. Midi Health is the virtual care clinic for women navigating midlife hormonal transition, offering FDA-approved medications, supplements and lifestyle coaching - all covered by insurance. Visit joinmidi.com to book your virtual visit today. — LINKS:  Stanford Medicine: https://med.stanford.edu/ RAISE Health: https://med.stanford.edu/raisehealth  Subscribe to Second Opinion Newsletter: https://secondopinion.media/   — FOLLOW https://www.linkedin.com/in/lloydminor/  https://www.linkedin.com/in/christinafarr/ https://www.linkedin.com/in/lubagreenwood/ https://www.linkedin.com/in/ashzenooz/ — TIMESTAMPS: (00:00) Intro (03:50) Challenges in healthcare and potential solutions (06:49) AI in medical practice (11:01) The future of medical education (19:33) Encouraging careers in medicine (28:56) Preventative care and health policy (31:46) Advances in cancer treatment (32:48) Innovations in early diagnosis and preventative strategies (33:18) Challenges in the US healthcare system (34:17) Reflections on academic leadership during Covid-19 (35:50) Stanford's response to the Covid-19 crisis (38:49) Balancing academic freedom and public health (40:37) Practical solutions during the pandemic (41:20) Innovations in healthcare (42:37) The future of ai and digital health (49:11) The debrief

In this episode of Second Opinion, Christina Farr, Ash Zenooz, and Luba Greenwood discuss the integration and evaluation of digital tools in healthcare with guest Caroline Pearson from the Peterson Health Technology Institute. They explore the challenges in demonstrating clinical effectiveness and affordability of digital health solutions, using diabetes management tools as a case example. They address the role of evidence in the healthcare system, potential biases in standard evaluation practices, and the need for improved data sharing between digital health companies and traditional healthcare providers. — SPONSOR:  👩‍⚕️ Hot flashes, insomnia, brain fog? You don't have to accept these as just another part of aging. Midi Health is the virtual care clinic for women navigating midlife hormonal transition, offering FDA-approved medications, supplements and lifestyle coaching - all covered by insurance. Visit joinmidi.com to book your virtual visit today. — LINKS:  Peterson Health Technology Institute: https://phti.org/ Peterson Center on Healthcare: https://petersonhealthcare.org/  Nonlinear dynamics of multi-omics profiles during human aging: https://www.nature.com/articles/s43587-024-00692-2  New Report Finds That Digital Diabetes Management Tools Fail to Deliver Meaningful Health Benefits to Patients While Increasing Spending: https://phti.org/announcement/new-report-finds-that-digital-diabetes-management-tools-fail-to-deliver-meaningful-health-benefits-to-patients-while-increasing-spending/  Subscribe to Second Opinion Newsletter: https://secondopinion.media/   — FOLLOW: https://www.linkedin.com/in/pearsoncaroline/  https://www.linkedin.com/in/christinafarr/ https://www.linkedin.com/in/lubagreenwood/ https://www.linkedin.com/in/ashzenooz/ — TIMESTAMPS: (00:00) Intro (01:39) Discussion about super aging (02:54) Introducing Caroline Pearson (04:16) Challenges in digital health solutions (05:58) The role of evidence in digital health (16:41) Employer-sponsored health insurance concerns (20:05) Collaboration and data sharing in health tech (32:05) The future of health tech and patient outcomes (33:30) Conclusion and final thoughts (34:37) The debrief

In this episode of Second Opinion, Christina Farr, Ash Zenooz, and Luba Greenwood discuss the evolving landscape of healthcare leadership with Oxeon CEO Sonia Millsom. They explore what makes a great healthcare CEO, covering current talent market trends, qualities of successful leaders, and the valuable roles of executive chairs in a company. Sonia offers invaluable insights into the art of relationship-building, the importance of rigorous candidate evaluation, and the strategic decision-making that fuels successful hiring and partnerships — RECOMMENDED PODCAST:  🎙️Turpentine VC Investor Erik Torenberg interviews partners at the top VCs in the world to learn their approach to the art and science of building a successful venture firm. Apple: https://podcasts.apple.com/us/podcast/id1701006772 Spotify: https://open.spotify.com/show/3Yb8ErLRnyoAqn4Y6NegTx — SPONSOR: 👩‍⚕️ Hot flashes, insomnia, brain fog? You don't have to accept these as just another part of aging. Midi Health is the virtual care clinic for women navigating midlife hormonal transition, offering FDA-approved medications, supplements and lifestyle coaching - all covered by insurance. Visit joinmidi.com to book your virtual visit today. — LINKS:  Oxeon: https://www.oxeon.com/ Subscribe to Second Opinion Newsletter: https://secondopinion.media/   — FOLLOW: https://www.linkedin.com/in/sonia-millsom-a1b993a/  https://www.linkedin.com/in/christinafarr/ https://www.linkedin.com/in/lubagreenwood/ https://www.linkedin.com/in/ashzenooz/ — TIMESTAMPS: (00:00) Intro (03:28) Current market dynamics and talent trends (06:04) Challenges and changes in the C-suite (12:38) The reality of being a first-time CEO (15:53) Hot and cold: trends in healthtech (19:40) Negotiating offers and equity (23:06) Understanding company valuations (24:52) Breaking into the tech industry (26:17) Advisory work and board positions (27:14) Challenges and importance of board chairs (28:37) Effective interviewing and hiring practices (30:59) The human element in recruitment (38:05) The debrief

In this episode of the Second Opinion Podcast, Christina Farr, Ash Zenooz, and Luba Greenwood engage in a candid conversation with Dr. Isaac (Zak) Kohane, a renowned AI expert and chair at Harvard Medical School's Department of Biomedical Informatics.  Zak expresses his optimism about AI in healthcare, sharing personal anecdotes to illustrate how tools like ChatGPT can enhance patient care by providing detailed and understandable information, and highlights AI's potential to address healthcare system gaps by complementing human doctors. They explored regulatory issues, data privacy concerns, and the importance of patient control over their health data, while emphasizing the need for a balanced approach that prioritizes patient care and ethical guidelines. — SPONSORS: 👩‍⚕️ Hot flashes, insomnia, brain fog? You don't have to accept these as just another part of aging. Midi Health is the virtual care clinic for women navigating midlife hormonal transition, offering FDA-approved medications, supplements and lifestyle coaching - all covered by insurance. Visit joinmidi.com to book your virtual visit today. 🩺 AWELL: Transform your healthcare operations with Awell! Say goodbye to manual work and Excel hell. Awell's CareOps orchestration platform helps design, implement, and improve care flows in days. Trusted by Astrana Health, Commons Clinic, and Better Health, Awell automates processes for faster care model improvements in 2 days or less. Visit awellhealth.com and mention Second Opinion for a free bootcamp. — LINKS:  Department of Biomedical Informatics at Harvard Medical School: https://dbmi.hms.harvard.edu/  NEJM AI, a journal from the publishers of the New England Journal of Medicine: https://www.nejm.org/  The AI Revolution in Medicine: GPT-4 and Beyond: https://www.amazon.com/AI-Revolution-Medicine-GPT-4-Beyond-ebook/dp/B0BXNVM6FC AMIE: A research AI system for diagnostic medical reasoning and conversations: https://research.google/blog/amie-a-research-ai-system-for-diagnostic-medical-reasoning-and-conversations/  Medical Artificial Intelligence and Human Values: https://www.nejm.org/doi/full/10.1056/NEJMra2214183  Transformer: A Novel Neural Network Architecture for Language Understanding: https://research.google/blog/transformer-a-novel-neural-network-architecture-for-language-understanding/  Subscribe to Second Opinion Newsletter: https://secondopinion.media/   — FOLLOW: https://www.linkedin.com/in/isaac-kohane-729b03  https://www.linkedin.com/in/christinafarr/ https://www.linkedin.com/in/lubagreenwood/ https://www.linkedin.com/in/ashzenooz/ — TIMESTAMPS: (00:00) Intro (02:24) Skepticism in advanced technology (04:56) AI in Medicine: Personal Anecdotes (07:29) Challenges in healthcare access (08:26) The role of ai in patient empowerment (11:26) Human clinicians vs. AI (19:45) Sponsor: Awell (20:57) Privacy concerns with AI (25:13) HIPAA compliance and medical data (26:19) Bias and alignment in AI models (29:00) The role of AI in medical decision making (33:13) Challenges in AI regulation (38:21) The future of AI in healthcare (43:56) Wrap (45:05) The Debrief

In this episode of Second Opinion, Christina Farr is joined by Carine Carmy, CEO of Origin to discuss the overlooked aspects of women's healthcare, a case for a physical clinic, and funding stigmatized fields within the complex healthcare landscape. Carine shares valuable insights on scaling the business, the importance of evidence-based care, and the future of pelvic health, including the potential impact of AI and digital health. — RECOMMENDED PODCAST: 🎙️This Won't Last Eavesdrop on Keith Rabois, Kevin Ryan, Logan Bartlett, and Zach Weinberg's monthly backchannel. They unpack their hottest takes on the future of tech, business, venture, investing, and politics. Apple Podcasts: https://podcasts.apple.com/us/podcast/this-wont-last-with-keith-rabois-kevin-ryan-logan/id1765665937 Spotify: https://open.spotify.com/show/2HwSNeVLL1MXy0RjFPyOSz YouTube: https://www.youtube.com/@ThisWontLastpodcast  — SPONSORS: 👩‍⚕️ Hot flashes, insomnia, brain fog? You don't have to accept these as just another part of aging. Midi Health is the virtual care clinic for women navigating midlife hormonal transition, offering FDA-approved medications, supplements and lifestyle coaching - all covered by insurance. Visit joinmidi.com to book your virtual visit today. 🩺 AWELL. Transform your healthcare operations with Awell! Say goodbye to manual work and Excel hell. Awell's CareOps orchestration platform helps design, implement, and improve care flows in days. Trusted by Astrana Health, Commons Clinic, and Better Health, Awell automates processes for faster care model improvements in 2 days or less. Visit awellhealth.com and mention Second Opinion for a free bootcamp. — LINKS: Subscribe to Second Opinion Newsletter: https://secondopinion.media/  Origin: https://www.theoriginway.com/  — FOLLOW: https://www.linkedin.com/in/carinecarmy/  https://www.linkedin.com/in/christinafarr/ https://www.linkedin.com/in/lubagreenwood/ https://www.linkedin.com/in/ashzenooz/ — TIMESTAMPS: (00:00) Intro (01:43) The origin story of Origin (03:31) Challenges in women's health (04:02) Understanding pelvic floor therapy (05:10) Pain and gaslighting in healthcare (07:39) Building a business in women's health (10:16) Navigating health plan coverage (13:51) Sponsor: Awell (15:02) Scaling and fundraising challenges (17:42) Clinic setup and expansion (25:36) The importance of evidence-based care (29:05) Wrap

In this episode of Second Opinion, hosts Christina Farr, Ash Zenooz, and Luba Greenwood dive into the intricacies of the behavioral health industry with Alex Katz, CEO of Two Chairs. They discuss the misconceptions and challenges within the mental health system, the importance of finding the right therapeutic fit, and the impact of venture capital in driving both quality and accessibility in mental health services. Alex highlights the need for personalized care, the evolving perception of therapy thanks to platforms like TikTok, and the potential and limitations of AI in therapy, emphasizing the irreplaceable value of human therapists. — RECOMMENDED PODCASTS: 🎙️This Won't Last Eavesdrop on Keith Rabois, Kevin Ryan, Logan Bartlett, and Zach Weinberg's monthly backchannel. They unpack their hottest takes on the future of tech, business, venture, investing, and politics. Apple Podcasts: https://podcasts.apple.com/id1765665937 Spotify: https://open.spotify.com/show/2HwSNeVLL1MXy0RjFPyOSz YouTube: https://www.youtube.com/@ThisWontLastpodcast 🎙️Turpentine VC Investor Erik Torenberg interviews partners at the top VCs in the world to learn their approach to the art and science of building a successful venture firm. Apple: https://podcasts.apple.com/us/podcast/id1701006772 Spotify: https://open.spotify.com/show/3Yb8ErLRnyoAqn4Y6NegTx — SPONSORS: 👩‍⚕️ Hot flashes, insomnia, brain fog? You don't have to accept these as just another part of aging. Midi Health is the virtual care clinic for women navigating midlife hormonal transition, offering FDA-approved medications, supplements and lifestyle coaching - all covered by insurance. Visit joinmidi.com to book your virtual visit today. 🩺 AWELL. Transform your healthcare operations with Awell! Say goodbye to manual work and Excel hell. Awell's CareOps orchestration platform helps design, implement, and improve care flows in days. Trusted by Astrana Health, Commons Clinic, and Better Health, Awell automates processes for faster care model improvements in 2 days or less. Visit awellhealth.com and mention Second Opinion for a free bootcamp. — LINKS: Subscribe to Second Opinion Newsletter: https://secondopinion.media/  Two Chairs: http://www.twochairs.com/  — FOLLOW: https://www.linkedin.com/in/alexjkatz/  https://www.linkedin.com/in/christinafarr/ https://www.linkedin.com/in/lubagreenwood/ https://www.linkedin.com/in/ashzenooz/ — TIMESTAMPS: 00:00 Intro 01:14 Behavioral health industry insights 02:04 Alex Katz's journey with Two Chairs 05:02 Navigating the mental health landscape 08:22 Business models in mental health 14:04 Barriers to mental health access 16:08 Sponsor: Awell 19:56 Behavioral health companies and cost reduction 22:00 The crisis in therapy retention 23:41 Youth mental health challenges 25:40 Gen Z and therapy culture 29:14 The importance of hybrid care models 31:31 Skepticism around ai therapists 36:00 The Debrief

In this episode of Second Opinion, Leslie Schrock, author of Bumpin' and Fertility Rules, joins Christina Farr, Ash Zenooz, and Luba Greenwood to discuss women's health, men's health, and fertility. They dive into why men need to be more involved in fertility and pregnancy conversations (it's not just a women's issue!). They address the gaps in women's health research, including the lack of understanding about how drugs and diets (like intermittent fasting) affect women differently than men. Leslie emphasizes the need for more honest, comprehensive information about pregnancy and women's health. They also discuss the potential future of women's health companies and the need for a more holistic approach to addressing health concerns beyond reproductive issues. — RECOMMENDED PODCAST: 🎙️ This Won't Last - Eavesdrop on Keith Rabois, Kevin Ryan, Logan Bartlett, and Zach Weinberg's monthly backchannel. They unpack their hottest takes on the future of tech, business, venture, investing, and politics. Apple Podcasts: https://podcasts.apple.com/us/podcast/id1765665937 Spotify: https://open.spotify.com/show/2HwSNeVLL1MXy0RjFPyOSz YouTube: https://www.youtube.com/@ThisWontLastpodcast — SPONSORS: 👩‍⚕️ Hot flashes, insomnia, brain fog? You don't have to accept these as just another part of aging. Midi Health is the virtual care clinic for women navigating midlife hormonal transition, offering FDA-approved medications, supplements and lifestyle coaching - all covered by insurance. Visit joinmidi.com to book your virtual visit today. 🩺 AWELL. Transform your healthcare operations with Awell! Say goodbye to manual work and Excel hell. Awell's CareOps orchestration platform helps design, implement, and improve care flows in days. Trusted by Astrana Health, Commons Clinic, and Better Health, Awell automates processes for faster care model improvements in 2 days or less. Visit awellhealth.com and mention Second Opinion for a free bootcamp. — LINKS: Subscribe to Second Opinion Newsletter: https://secondopinion.media/  Bumpin: https://www.amazon.com/Bumpin-Pregnancy-Navigating-Wonderful-Conception/dp/198213044X  Fertility Rules: https://www.amazon.com/Fertility-Rules-Definitive-Female-Reproductive-ebook/dp/B0BHTLCWZ7  — FOLLOW: Leslie: https://www.linkedin.com/in/leslieschrock/  Christina: https://www.linkedin.com/in/christinafarr/ Luba: https://www.linkedin.com/in/lubagreenwood/ Ash: https://www.linkedin.com/in/ashzenooz/ — TIMESTAMPS: (00:00) Intro (01:37) Leslie Schrock's personal journey (02:57) The reality of pregnancy (06:55) Understanding fertility and ovulation (08:47) Challenges in women's health education (13:50) Sponsor: Awell (15:00) Investing in women's health (25:54) Understanding drug metabolism in women (26:09) Men's role in women's health (26:38) The importance of inclusive pregnancy literature (28:45) Heart health: gender differences and misconceptions (30:50) Birth control and stroke risks (31:46) Challenges in women's health research (37:11) The impact of nutrition and fasting on women's health (39:19) Future of women's health companies (41:09) Suggestions on future books and research in women's health (43:55) Wrap (46:07) The debrief

In this episode of Second Opinion, hosts Christina Farr, Ash Zenooz, and Luba Greenwood sit down with Owen Tripp, the CEO of Included Health. They discuss digital health models, the challenges and opportunities in selling directly to employers, growing digital health companies, and the potential return to a more personalized, concierge-style primary care model to actually make a difference in people's health. — RECOMMENDED PODCAST: 🎙️ This Won't Last - Eavesdrop on Keith Rabois, Kevin Ryan, Logan Bartlett, and Zach Weinberg's monthly backchannel. They unpack their hottest takes on the future of tech, business, venture, investing, and politics. Apple Podcasts: https://podcasts.apple.com/us/podcast/id1765665937 Spotify: https://open.spotify.com/show/2HwSNeVLL1MXy0RjFPyOSz YouTube: https://www.youtube.com/@ThisWontLastpodcast — SPONSORS: 👩‍⚕️ Hot flashes, insomnia, brain fog? You don't have to accept these as just another part of aging. Midi Health is the virtual care clinic for women navigating midlife hormonal transition, offering FDA-approved medications, supplements and lifestyle coaching - all covered by insurance. Visit joinmidi.com to book your virtual visit today. 🩺 AWELL. Transform your healthcare operations with Awell! Say goodbye to manual work and Excel hell. Awell's CareOps orchestration platform helps design, implement, and improve care flows in days. Trusted by Astrana Health, Commons Clinic, and Better Health, Awell automates processes for faster care model improvements in 2 days or less. Visit https://awellhealth.com and mention Second Opinion for a free bootcamp. — LINKS:  Subscribe to Second Opinion Newsletter: https://secondopinion.media/  Thinking of selling into the employer? You probably shouldn't: https://secondopinion.media/p/thinking-of-selling-into-the-employer  The thing that is breaking digital health is marketing: https://secondopinion.media/p/the-thing-that-is-breaking-digital — FOLLOW: https://www.linkedin.com/in/owenwtripp/  https://www.linkedin.com/in/christinafarr/ https://www.linkedin.com/in/lubagreenwood/ https://www.linkedin.com/in/ashzenooz/ — TIMESTAMPS: (00:00) Intro (01:16) Owen Tripp's journey in digital health (02:04) Challenges in healthcare vs. other sectors (03:29) Building a business model in healthcare (05:07) Grand Rounds: from concept to success (08:07) The role of AI in healthcare (13:48) Sponsor: Awell (14:50) Growth strategies in digital health (17:33) Selling digital health solutions to employers (19:10) Cancer care and digital health (22:22) Navigating employer sales (26:12) Utilization and awareness of digital health services (35:01) The future of digital health and primary care (38:57) The Debrief

In this episode of Second Opinion, Meg FitzGerald, a nurse turned private equity investor, offers insights into how VCs and PEs are thinking of investing in healthcare and everything founders should know to raise from both. She discusses the slowdown in private equity deals due to high interest rates and market uncertainty, and highlights the merging of venture capital and private equity in healthcare, particularly in growth capital. She shares her experience transitioning from a clinical background to private equity, underscoring the value of healthcare expertise in investment decisions. Second Opinion is a podcast from Turpentine. Learn more: www.turpentine.co — SPONSORS: 👩‍⚕️ Hot flashes, insomnia, brain fog? You don't have to accept these as just another part of aging. Midi Health is the virtual care clinic for women navigating midlife hormonal transition, offering FDA-approved medications, supplements and lifestyle coaching - all covered by insurance. Visit joinmidi.com to book your virtual visit today. 🩺 AWELL. Transform your healthcare operations with Awell! Say goodbye to manual work and Excel hell. Awell's CareOps orchestration platform helps design, implement, and improve care flows in days. Trusted by Astrana Health, Commons Clinic, and Better Health, Awell automates processes for faster care model improvements in 2 days or less. Visit awellhealth.com and mention Second Opinion for a free bootcamp. — FOLLOW: Meg https://www.linkedin.com/in/meghanmfitzgerald/ Christina https://www.linkedin.com/in/christinafarr/ Luba https://www.linkedin.com/in/lubagreenwood/ Ash https://www.linkedin.com/in/ashzenooz/ — RECOMMENDED PODCAST: 🎙️ This Won't Last - Eavesdrop on Keith Rabois, Kevin Ryan, Logan Bartlett, and Zach Weinberg's monthly backchannel. They unpack their hottest takes on the future of tech, business, venture, investing, and politics. Apple Podcasts: https://podcasts.apple.com/us/podcast/id1765665937 Spotify: https://open.spotify.com/show/2HwSNeVLL1MXy0RjFPyOSz YouTube: https://www.youtube.com/@ThisWontLastpodcast — TIMESTAMPS: (00:00) Intro (00:59) Meet Meg FitzGerald: Nurse and Private Equity Investor (01:19) Private Equity in Healthcare: Current Market Dynamics (03:09) Venture Capital vs. Private Equity in Healthcare (05:00) Challenges and Opportunities in Health Tech (11:23) The Role of Private Equity (18:51) Awell (19:49) Advice for Healthcare Professionals Entering Private Equity (31:26) The debrief (35:00) Wrap

In this eye-opening episode, Christina Farr and Luba Greenwood dive deep into the challenges big tech faces in healthcare with serial entrepreneur and Cherish CEO Sumit Nagpal. Drawing from his experience founding five companies over the past 25 years and his time working with Steve Jobs at NeXT, Nagpal offers unique insights into why tech giants struggle to gain traction in the medical world. They discuss: Apple's healthcare ambitions, the untapped potential of hardware in health tech, the importance of understanding healthcare business models, and how lessons from the diagnostics industry could shape the future of digital health innovation. — SPONSORS: 👩‍⚕️ Hot flashes, insomnia, brain fog? You don't have to accept these as just another part of aging. Midi Health is the virtual care clinic for women navigating midlife hormonal transition, offering FDA-approved medications, supplements and lifestyle coaching - all covered by insurance. Visit joinmidi.com to book your virtual visit today. 🩺 AWELL. Transform your healthcare operations with Awell! Say goodbye to manual work and Excel hell. Awell's CareOps orchestration platform helps design, implement, and improve care flows in days. Trusted by Astrana Health, Commons Clinic, and Better Health, Awell automates processes for faster care model improvements in 2 days or less. Visit awellhealth.com and mention Second Opinion for a free bootcamp. — LINKS:  Cherish Health: https://www.cherishhealth.com/ Subscribe to Second Opinion Newsletter: https://secondopinion.media/  — FOLLOW: Sumit: https://www.linkedin.com/in/sumitknagpal/ Christina https://www.linkedin.com/in/christinafarr/ Luba https://www.linkedin.com/in/lubagreenwood/ Ash https://www.linkedin.com/in/ashzenooz/ — RECOMMENDED PODCAST: TURPENTINE VC 🎙️ This Won't Last - Eavesdrop on Keith Rabois, Kevin Ryan, Logan Bartlett, and Zach Weinberg's monthly backchannel. They unpack their hottest takes on the future of tech, business, venture, investing, and politics. Apple Podcasts: https://podcasts.apple.com/us/podcast/id1765665937 Spotify: https://open.spotify.com/show/2HwSNeVLL1MXy0RjFPyOSz YouTube: https://www.youtube.com/@ThisWontLastpodcast — TIMESTAMPS: (00:00) Intro (02:04) Why big tech fails in healthcare (05:00) Has Apple succeeded in becoming a healthcare company? (08:44) Finding adjacencies (10:11) Billionaires' health concerns driving tech investments (14:19) Sponsor: Awell (15:19) Revolving door of healthcare leaders in tech (17:14) Culture clash in tech-healthcare partnerships (19:26) NVIDIA's successful approach to healthcare (20:21) Waystar IPO (24:10) Limited options for health tech companies (26:19) Diagnostics industry parallels with digital health (28:22) Aligning Incentives (31:54) "Follow the Money" approach to healthcare solutions (34:41) The Debrief

In this episode of Second Opinion, hosts Christina Farr, Ash Zenooz, and Luba Greenwood are joined by Daphne Zohar, Founder and CEO of Seaport Therapeutics. They talk about the complexities of drug development, the investment in biotech via big tech VCs, and the future of mental health treatments. Daphne also shares her insights on biotech today, drug development misconceptions and complex regulatory challenges the industry is facing. Daphne was the founder, CEO and a Board Member of PureTech Health (Nasdaq: PRTC, LSE: PRTC) where she also co-founded PureTech’s entities, including Karuna Therapeutics (acquired by Bristol Myers Squibb). — SPONSOR:  👩‍⚕️ Hot flashes, insomnia, brain fog? You don't have to accept these as just another part of aging. Midi Health is the virtual care clinic for women navigating midlife hormonal transition, offering FDA-approved medications, supplements and lifestyle coaching - all covered by insurance. Visit joinmidi.com to book your virtual visit today. — LINKS:  Seaport Therapeutics: https://seaporttx.com/ Seaport Therapeutics $100M series A: https://seaporttx.com/wp-content/uploads/2024/04/20240409_press_release.pdf PureTech: https://www.puretechhealth.com/  Karuna Therapeutics: https://karunatx.com/  Subscribe to Second Opinion Newsletter: https://secondopinion.media/  — FOLLOW: Daphne https://www.linkedin.com/in/daphnezohar/ Christina https://www.linkedin.com/in/christinafarr/ Luba https://www.linkedin.com/in/lubagreenwood/ Ash https://www.linkedin.com/in/ashzenooz/ — RECOMMENDED PODCAST: TURPENTINE VC 🎙️ This Won't Last - Eavesdrop on Keith Rabois, Kevin Ryan, Logan Bartlett, and Zach Weinberg's monthly backchannel. They unpack their hottest takes on the future of tech, business, venture, investing, and politics. Apple Podcasts: https://podcasts.apple.com/us/podcast/id1765665937 Spotify: https://open.spotify.com/show/2HwSNeVLL1MXy0RjFPyOSz YouTube: https://www.youtube.com/@ThisWontLastpodcast — TIMESTAMPS: (00:00) Intro (01:42) Daphne's Background and Achievements (02:29) Challenges in Mental Health and Neuro Space (05:52) Drug Development Journey and Challenges (10:40) Opportunities and Challenges for Tech Investors in Biotech (16:16) Regulatory Challenges and Industry Impact (26:39) Biosecure Act and National Security (28:02) The Debrief

On the first episode of Second Opinion, Christina Farr, Ash Zenooz, and Luba Greenwood chat with Dr. Robin Berzin, the Founder & CEO of Parsley Health. Robin shares her journey from being a physician to founding Parsley Health, a digital health company that uses root cause medicine to drive powerful outcomes for patients with complex health needs. She also talks about how breakthroughs in data and AI are helping redefine primary care with data-driven insights. They explore crucial healthcare questions like "Whose job is it to prevent chronic disease?" and discuss whether digital health can deliver on prevention, treatment, and longevity. They reflect on the shortcomings of primary care, the impact of the standard American diet on health, the latest studies on cortisol, and the importance of a holistic approach to medicine. Thank you to our sponsor Awell, the leading CareOps platform. — SPONSORS: 👩‍⚕️ Hot flashes, insomnia, brain fog? You don't have to accept these as just another part of aging. Midi Health is the virtual care clinic for women navigating midlife hormonal transition, offering FDA-approved medications, supplements and lifestyle coaching - all covered by insurance. Visit joinmidi.com to book your virtual visit today. 🩺 AWELL. Transform your healthcare operations with Awell! Say goodbye to manual work and Excel hell. Awell's CareOps orchestration platform helps design, implement, and improve care flows in days. Trusted by Astrana Health, Commons Clinic, and Better Health, Awell automates processes for faster care model improvements in 2 days or less. Visit awellhealth.com and mention Second Opinion for a free bootcamp. — LINKS: Subscribe to Robin’s Newsletter: https://robinberzinmd.com/  Subscribe to Parsley Health Newsletter: https://www.parsleyhealth.com/blog/category/news/  Parsley Health: https://www.parsleyhealth.com   ARTICLES MENTIONED: Health care's "churn" problem: https://secondopinion.media/p/health-cares-churn-problem  How to balance cortisol levels to increase energy and lose weight: https://robinberzinmd.com/how-to-balance-cortisol-levels-to-increase-energy-and-lose-weight/  A Lot of What You’ve Heard About Cortisol Is Wrong: https://www.wsj.com/health/wellness/cortisol-stress-hormone-adrenal-fatigue-02aab49a  — FOLLOW: https://www.linkedin.com/in/robin-berzin-md/ https://www.linkedin.com/in/christinafarr/ https://www.linkedin.com/in/lubagreenwood/ https://www.linkedin.com/in/ashzenooz/ Subscribe to Second Opinion Newsletter: https://secondopinion.media/  — TIMESTAMPS: (00:00) Intro (02:30) Robin Berzin's Journey: From Physician to CEO of Parsley Health (07:11) Functional Medicine (aka Root Cause Medicine) and Parsley Health (09:31) Challenges in Traditional Healthcare (11:06) The Role of AI and Data in Healthcare (14:34) Whose Job Is It To Prevent Chronic Disease? (21:19) SPONSOR: Awell Health (22:22) Healthcare’s “Churn” Problem, Insurance and Healthcare Costs (27:57) Partnering with Insurance Companies (30:43) How Diet and Lifestyle Impact Health (34:34) The Role of Cortisol in the Body (36:32) Wrap This podcast is part of the Turpentine podcast network. Learn more: turpentine.co

Second Opinion doesn't hold back. Join Christina Farr, Ash Zenooz, Luba Greenwood, as they bring influential entrepreneurs, experts and investors into the ring for candid conversations at the frontlines of healthcare and digital health every week. Episode 1 with Robin Berzin, CEO of Parsley Health, will be available starting on July 31, 2024. Subscribe to Second Opinion wherever you get your podcasts. Learn more at https://www.podpage.com/secondopinion/ Til then, meet your hosts:  Christina Farr draws on a decade of experience covering the industry as a reporter at CNBC, Fast Company and Reuters, as well as an investor at OMERS Ventures. During her tenure as a reporter, she broke some big health-tech stories ranging from Amazon’s first moves into the sector to Apple’s secretive acquisitions.  Luba Greenwood, JD is a veteran biotech CEO and investor. She is the managing partner and founder of the Dana-Farber Cancer Institute venture fund and has served as CEO and Chair of multiple companies including Kojin. She has led over $10b in deals and served in leadership roles at large healthcare and tech companies, including Roche and Google. She is a thought leader in the industry and senior lecturer at Harvard. Ash Zenooz, MD — former CEO of Commure and partner at Luxeda Holdings. As former CEO of Commure, she drove over 550% ARR growth and led a merger. Previously, she grew Salesforce's global health and life sciences unit to $2.5b ARR. Ash also served as Chief Medical Officer at the VA, overseeing an $80B portfolio and leading telehealth and precision medicine reforms.  This season, we’re tackling meaty topics like biosecurity, the latest in telemedicine, why patient acquisition is so hard, and the pros and cons of VC versus private equity in funding startups in the healthtech space.