Revolution Health Radio

In this episode of Revolution Health Radio, Chris takes a deep dive into the latest research on ultra-processed foods, their potential impact on health, what distinguishes ultra-processed foods from minimally-processed and traditionally-processed foods, and why a Nutrition Facts label may not capture everything that matters about a food. He examines research linking higher ultra-processed food consumption with overeating, weight gain, metabolic dysfunction, cardiovascular disease, and other adverse health outcomes, and also explores potential mechanisms, including disruption of the food matrix, changes to the gut microbiome, intestinal barrier dysfunction, inflammation, oxidative stress, food additives, and effects on the gut-brain axis. The post RHR: The Hidden Harms of Ultra-Processed Foods appeared first on Chris Kresser.

In this episode of Revolution Health Radio, Chris Kresser explores what biological age really means and examines the research behind today's most popular longevity claims. He explains how epigenetic clocks and DNA methylation are used to estimate biological aging, why these tests may be less precise for individuals than they appear, and what studies like the CALERIE trial tell us about slowing the aging process. You'll also learn why reversing a biological age number isn't the same as reversing aging, and how meaningful improvements in muscle strength, cognition, metabolic health, and physical function can be achieved at virtually any age. He also offers a practical framework to build a strong foundation of sleep, nutrition, movement, stress management, connection, and purpose before investing in advanced longevity technologies or supplements. The post RHR: Can You Reverse Your Biological Age? appeared first on Chris Kresser.

In this episode of Revolution Health Radio, Chris breaks down the science behind joint pain, osteoarthritis, and cartilage degeneration while challenging one of the most common assumptions about joint health—that glucosamine and chondroitin are the gold standard for protecting cartilage and relieving pain. He explains why current clinical evidence no longer supports those supplements as the best option and instead reviews the clinical evidence supporting three promising ingredients—native type II collagen, natural eggshell membrane, and Boswellia serrata—and discusses how each works through a unique biological pathway to reduce inflammation, preserve cartilage, improve mobility, and support long-term joint function. The post RHR: My Top 3 Ingredients for Joint Health, Mobility, and Cartilage Repair appeared first on Chris Kresser.

In this episode of Revolution Health Radio, Chris Kresser sits down with renowned neurologist and bestselling author Dr. David Perlmutter to discuss the emerging science of microglia—the brain's immune cells—and why they may hold the key to preventing cognitive decline and Alzheimer's disease. Drawing from his new book, Brain Defenders, Dr. Perlmutter explains how lifestyle factors such as nutrition, exercise, sleep, metabolic health, and gut health influence whether microglia protect the brain or contribute to chronic inflammation and neurodegeneration. Together, they challenge the outdated notion that dementia is largely predetermined by genetics, highlighting growing evidence that proactive lifestyle interventions can preserve—and even improve—brain function throughout life. The post RHR: Why Microglia Are the Key to Brain Health, with Dr. David Perlmutter appeared first on Chris Kresser.

What if one of the most overlooked risk factors for cognitive decline isn’t in the brain—but in the mouth? In this episode of Revolution Health Radio, Chris Kresser explores the emerging science linking oral health to brain health. He examines how chronic gum disease may contribute to cognitive decline, Alzheimer’s disease, and Parkinson’s disease through systemic inflammation, direct bacterial migration to the brain, and disruption of the oral-gut-brain axis. Drawing on recent research, Chris explains why periodontal disease should be considered a key factor in dementia prevention, why this conversation remains absent from mainstream care, and practical steps listeners can take to protect both oral and long-term cognitive health. The post RHR: Your Mouth is Talking To Your Brain—And You Should Be Listening appeared first on Chris Kresser.