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16 Minutes News by a16z

Author: Andreessen Horowitz

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Introducing our new podcast, 16 Minutes, a short news podcast where we cover the top headlines of the week, the a16z podcast way -- why are these topics in the news; what's real, what's hype from our vantage point; and what are our experts' quick takes on these trends?

About the a16z Podcast: Discusses tech and culture trends, news, and the future -- especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This podcast is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes -- and now shows -- are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!
28 Episodes
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If the best way to know whether a medicine is effective is through a clinical trial, then where does (and doesn't) real-world data and real-world evidence come in? The topic is always top of mind in drug development, with additional focus as of 2016 thanks to the 21st Century Cures Act -- but is especially heated lately given recent concerns and claims around particular drugs in the context of the novel coronavirus pandemic.So in this short-but-deep dive episode of 16 Minutes on the News, a16z general partner in bio Vijay Pande -- previously a professor of Chemistry, Structural Biology, and Computer Science at Stanford University (as well as founder of Folding@Home) -- breaks down the debate between RWE vs. RCT (real world evidence and randomized controlled trials), in conversation with Sonal Chokshi. Is it a tradeoff between speed of innovation and safety, or is it a false dichotomy altogether? Where do and don't statistics come in when it comes to policy? How has, and could, the role of the FDA (as well as payers reimbursing healthcare) evolve here? And where can technology help?
The U.S. Federal Reserve recently made a range of moves -- from cutting interest rates to near zero (which it also did in the 2008 financial crisis) and using other tools -- to support "the flow of credit to households and businesses, thereby promote its maximum employment and price stability goals" during this current pandemic and public health crisis.However... what does this mean for small businesses, which may be most impacted? What's the difference between monetary and fiscal policy here; where does rhetoric (such as around buybacks vs. dividends) confuse; how does adjudication and disbursement work... and where could technology come in?In this short-but-deep dive episode of 16 Minutes on the News, a16z general partner on fintech Alex Rampell -- who also covered quantitative easing and more on a previous episode -- breaks it all down in 18 minutes, with useful analogies, in conversation with Sonal Chokshi.  How do we stop not just the novel coronavirus, but the economic virus, too? image: Edna Winti / Flickr
This episode of 16 Minutes on the News covers the U.S. Department of Health and Human Services' "historic rules" to provide patients more control of their data. They've been a long time coming, and despite recent fights over them, the final rules are now finally here as of this week.So in this short but deep dive, a16z bio experts -- general partner Julie Yoo and Venkat Mocherla in market development (in conversation with Sonal Chokshi) -- go into:0:47 how the rules fit into our healthcare system, especially with everything else going on right now in hospitals and beyond;3:11-8:37 what the rules specifically are and why they matter;6:21 concrete examples including why things like notifications are important;8:42 implications for providers and payers, including examples such as prior authorization;11:10 where privacy concerns do and don't come in, given how much information is contained in records;13:40 implications for startups, tech incumbents, and traditional players in healthcare, and new types of data down the road; and18:27 the bottomline.
This episode of 16 Minutes on the news covers:Google could bring Steam support to Chrome OS, according to an earlier unconfirmed report, and what that could mean for the broader gaming ecosystem, developers as well as devices -- with a16z general partner Andrew Chen and Jonathan Lai on the consumer team;New York restaurants and retail establishments can no longer reject cash payments under legislation that was passed by the City Council there; what this says about the banking system more broadly, why it's a regressive tax on the poor and therefore a progressive move -- at 8:57 with a16z general partner Alex Rampell on the fintech team;updates on COVID-19 disease -- at 16:44 based on latest reports from WHO and CDC as of Friday March 6....with Sonal Chokshi.---The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation.This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments for which the issuer has not provided permission for a16z to disclose publicly as well as unannounced investments in publicly traded digital assets) is available at https://a16z.com/investments/.Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.
This episode of 16 Minutes on the news covers:all the recent fintech acquisitions! from Intuit announcing it's acquiring Credit Karma this week to Morgan Stanley announcing it's acquiring E-trade last week to Visa acquiring Plaid last month, and so on -- what’s going on, why, and why now? -- with a16z general partner Anish Acharya;recent hearing on SEC's complaint against Telegram, which turns out not to be about cryptocurrency at large, a particular subset of cryptocurrencies, or whether a cryptocurrencly is inherently a security -- but may have broader implications for policy and policy making -- at 7:57 with a16z managing partner Scott Kupor;...in conversation with Sonal Chokshi.---The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation.This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments for which the issuer has not provided permission for a16z to disclose publicly as well as unannounced investments in publicly traded digital assets) is available at https://a16z.com/investments/.Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information. 
Coronavirus Updates

Coronavirus Updates

2020-02-1920:22

This episode covers the latest updates since our previous deep-dive on the novel coronavirus outbreak. We cover the latest developments -- new name, new declarations, new numbers, new definitions -- as well as:practical implications for the U.S. healthcare system given how it works today, and where we might go in the future -- with a16z general partner Julie Yoo, given our vantage point in tech; andhow the rt-PCR test works, and other updates about what the data do and don't tell us, and whether and what terms are useful or not -- with a16z bio partner Judy Savitskaya;...in conversation with Sonal Chokshi.Sources for this episode and/or other background links:latest numbers: cases in the U.S. (CDC, as of February 17, 2020); global cases (WHO situation report #25, February 14, 2020); spike in diagnosing cases as reported in China (SCMP, Scott Gottlieb)situation & policy statements/reports: CDC summary (as of February 14, 2020); "Annual report on global preparedness for health emergencies", WHO (Global Preparedness Monitoring Board, 2019)on definitions (of pandemics, endemics), other terms, and various naming conventions: "Understanding pandemics: What they mean, what they don't mean, and what comes next with the coronavirus", Helen Branswell, StatNews (February 12, 2020); on disease occurrence and levels (CDC); "misinfodemic"; best practices on naming new human infectious diseases (WHO); qPCR (Keith Robison)image: 2019 Novel Coronavirus (2019-nCoV), CDC, via Wikimedia Commons
This episode of 16 Minutes on the news covers:FICO credit score changes, what are they, do they matter? -- with a16z fintech general partners Angela Strange and Anish Acharya;electronic health record provider Epic's letter urging hospitals to oppose government regulations that would make it easier for patients and companies to access medical information, and where is the Plaid of healthcare? -- at 10:19 with a16z bio general partner Julie Yoo;...in conversation with Sonal Chokshi.Background links / pieces mentioned in this episode:Changes are coming to your credit score, Anna Bahney, CNN BusinessFICO changes could lower your credit score, AnnaMaria Andriotis, Wall Street JournalEpic’s CEO is urging hospital customers to oppose rules that would make it easier to share medical info & Epic and about 60 hospital chains come out against rules that would make it easier to share medical info, Chrissy Farr, CNBCHealth care data-sharing rules touch off intense lobbying fight, Darius Tahir, Politico ---The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation.This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments for which the issuer has not provided permission for a16z to disclose publicly as well as unannounced investments in publicly traded digital assets) is available at https://a16z.com/investments/.Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.
Coronavirus Outbreak

Coronavirus Outbreak

2020-01-3019:49

This episode of 16 Minutes on the news from a16z is all about the recent coronavirus outbreak -- or rather, a new type of coronavirus called 2019-nCoV for 2019 novel coronavirus. Since it's an ongoing and fast-developing news cycle, we take a quick snapshot for where we are, what we know, and what we don't know, and discuss the vantage point of where tech comes in. Topics covered include:definition of a virus, categories of coronavirusesorigins and spreadhow this stacks up so far against SARS and MERSspeed of sequencing, implications of genomic infospeed of information sharingR0 ("r-naught"/"nought") and what it measuresdifferent ways to think about how bad a given epidemic iscurrent moves and treatmentsOur a16z guest is Judy Savitskaya on the bio team, in conversation with Sonal Chokshi.Link sources or background readings for this episode:Centers for Disease Control and Prevention (in the U.S. Department of Health and Human Services) + typesWorld Health Organization (in the United Nations) -- situation report #6, January 26Other background readings / pieces mentioned in this episode: "Scientists are moving at record speed to create new coronavirus vaccines--but they may come too late", Jon Cohen, Science (AAAS), January 27"Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China", The Lancet, January 24"Discovery of a novel coronavirus associated with the recent pneumonia outbreak in humans and its potential bat origin", bioRxiv, January 2 *note - preprint, NOT peer reviewed*"The deceptively simple number sparking coronavirus fears", Ed Yong, The Atlantic, January 28 *this appeared AFTER this episode was recorded, so sharing here as additional reading only*
This episode of our news show teases apart what was just a concept, what's near from the annual Consumer Electronics Show (CES 2020). Board partner Steven Sinofsky (in conversation with Sonal Chokshi) takes us on a quick tour of the based on his annual field trip report from the floor.Topics covered include:folding screens and 8K displays5G, wi-fi 6, new millimeter wave 5Gtransportation: cars, voice, micromobilitysmart home automation and securitybatteries and USB-CArticles/ headlines in this episode:CES 2020: The Primordial Soup of Innovation by Steven Sinofsky, Learning by ShippingEight big takeways from CES 2020 by Dieter Bohn, The Verge
In this 19th episode of our news show, where we cover recent headlines from our vantage point in tech, we cover the following news items (in conversation with Sonal Chokshi):recent moves to regulate artificial intelligence (AI) software including the White House's recent guidance (and op-ed from the U.S. CTO) on AI in general, as well as limits to exports of specific AI software that went into effect this week -- with operating partner Frank Chen (whose talk was cited in an earlier White House report);recent activity on the topic of negative interest rates as well as quantitative easing, given recent remarks (and paper) from former chairman of the Federal Reserve Ben Bernanke -- with general partner Alex Rampell, who covers all things fintech.
For our first episode of 2020 -- #18 of our show 16 Minutes, where we cover recent headlines, the a16z way, from our vantage point in tech, and especially what's hype/ what's real -- we do one of our special deep-dive episodes on a single topic: personal genomics.It’s a turn of the decade — and January-appropriate! — look backward/ look forward given recent and past retrospective and prospective pieces in the media on the promise, and perils, of the ability to sequence one’s DNA and what it means for personalized medicine, criminal investigations, privacy, and so on.Our a16z expert for this episode is general partner Jorge Conde, who has a long history in the space, in conversation with host Sonal Chokshi. They cover everything from where genealogy databases and large datasets come in to fetal testing, multi-omics, and much more spanning past, present, and future.
On this show, we cover recent headlines, the a16z Podcast way -- what’s hype, what’s real; why they matter from our vantage point in tech -- and this week, we cover the following news (in conversation with Sonal Chokshi):Star War trailer premieres in... Fortnite? What's the significance of the latest Star Wars trailer debuting inside a video game over a movie theater or TV or even YouTube and Facebook? It has to do with the bigger picture of games, social networks, and virtual worlds; so what are the implications for marketers, game developers, and how we will live/work/play? -- with Jonathan Lai, consumer teamCongress warns tech companies to take action on encryption... or else! Concerned about protecting the most vulnerable Americans and devices "going dark" to law enforcement (especially given "several serious cases where we can't access the device in the time period where it is most important for us to access it"), Congress recently sent a warning to tech companies to get their "act together" on encryption... or else "we will impose our will on you", by this time next year. But what if we're having the wrong conversation to break the deadlock, and what conversation could we be having? -- with Martin Casado, general partner, and operating partner for security Joel de la GarzaRelevant/ related links:on gaming State of play: Six trends revolutionizing gaming by Jonathan Lai and Andrew ChenNew business models for gaming [podcast] with Kevin Chou, Chris Dixon, and Sonal ChokshiCome for the games, stay for the party [podcast] with Andrew Chen, Jonathan Lai, and Lauren MurrowTech trends changing gaming [podcast] with Tim Shafer, Justin Bailey, Herman Narula, and Sonal Chokshion security16 steps to securing your data (and life) by Joel de la Garza
This is the 16th episode of 16 Minutes, our news show where we cover the top headlines, the a16z Podcast way: what’s real / what’s hype; why they matter from our vantage point in tech.This week, we cover the following news (in conversation with Sonal Chokshi):NYSE & SEC back and forth over direct listings -- The NYSE recently proposed allowing companies to raise capital during direct listings (currently, they're different than IPOs in that there is no offering); the SEC rejected it; and they just filed a new proposal... but beyond this news and these artifacts, what's the bigger picture when it comes to other structural factors involved here? -- with Scott Kupor.vaping apps & Apple; FDA & CBD-- two recent moves: Apple banning 181 vaping apps from its app store, FDA issuing warning letters against 15 companies with products that have CBD in them; what's our quick take on the blurring lines between these two seemingly different bits of news? -- with Vijay Pande.Relevant/ related links:IPOs, direct listings, more:beyond the opening bell: what do (and don't) IPOs tell us about companies? by Scott Kupordirect listings, the myths and the facts [podcast] with Stacey Cunningham, Barry McCarthy, and Sonal Chokshiall about direct listings with Jamie McGurkthe curious case (and the behind-the-scenes story of) the OpenTable IPO [podcast] with Jeff Jordan, J.D. Moriarty, and Sonal Chokshion capital formation, smaller companies, and IPOs [testimony] by Scott Kupor---The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation.This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments for which the issuer has not provided permission for a16z to disclose publicly as well as unannounced investments in publicly traded digital assets) is available at https://a16z.com/investments/.Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.
This is the 15th episode of 16 Minutes, our news show where we cover the top headlines, the a16z Podcast way: what’s real / what’s hype; what's interesting from our vantage point in tech. This week (after a brief hiatus for our annual innovation event and November holidays), we cover the following news... in conversation with Sonal Chokshi:use of alternative data in credit underwriting -- Five federal regulatory agencies (the Federal Reserve Board, the Consumer Financial Protection Bureau, the Federal Deposit Insurance Corporation, the Office of the Controller of the Currency, and the National Credit Union Administration) recently issued a joint statement on the use of alternative data in credit underwriting; what does this news really indicate, and what are the implications for both consumers and companies? -- with Seema Amble and Rex Salisbury;big annual shopping days and retail trends -- From Black Friday to Cyber Monday to Singles' Day and Prime Day and seemingly unprecedented sales, where are we in the shift from offline to online commerce, on the so-called "death of retail", and on other tech (chatbots, logistics) changing shopping? -- with Jeff Jordan and Connie Chan.Relevant/ related links:credit, banking, data:use of cash-flow data in underwriting credit: empirical findings via FinRegLaba brief history of credit cards (or, what actually happens when you swipe) [animated video] with Alex Rampellon managing risk and uncertainty with Angela Strangeon non-bank financial firms (aka fintech is eating the world) by Angela Strangeon money, risk, and software [podcast] with Alex Rampellretail, logistics, etc.:the golden era of productivity, retail, supply chains [podcast] with Marc Levinson, Hanne Tidnam, and Sonal Chokshiwhere's my stuff, the lowdown on logistics and ops [podcast] with Jeff Jordanonline to offline 2.0 - experiments and examples from China with Connie Chanonline to offline (O2O) commerce by Alex Rampell the tipping point (e-commerce version) by Jeff Jordanso you want to compete with Amazon? by Jeff Jordan---The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation.This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments for which the issuer has not provided permission for a16z to disclose publicly as well as unannounced investments in publicly traded digital assets) is available at https://a16z.com/investments/.Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.
This is the 14th episode of 16 Minutes, our weekly-ish news show where we quickly cover the top headlines of the week, the a16z Podcast way: what’s real, what’s hype from our vantage point in tech. This week, we cover the following news -- with a16z experts general partner Julie Yoo and market dev partner Venkat Mocherla from the bio team, and former CSO/ a16z security operating partner Joel de la Garza -- in conversation with Sonal Chokshi:UPS drones deliver prescriptions -- For the first time ever, drones delivered prescription medication directly to residential homes and retirement homes in North Carolina this month; but why don't we already get drugs by delivery? And what's the significance of pharma as a node in the healthcare system?Apple opens health records to vets -- Apple and the Department of Veterans Affairs announced recently that veterans can now access their health information on their iPhones; why is (or isn't) this significant, and wherefore the promise of EHRs (electronic health records)?!hackers can use lasers to command voice devices -- Security researchers were able to send laser-powered “light commands” to smart assistants (including products like Amazon’s Alexa, Apple’s Siri, Facebook’s Portal, and Google Assistant) to take full control over them at specific distances; how worried should we be, and how does this affect the future of a voice-enabled world?Relevant/ related links:on healthcare delivery and the pharma industry:software eats care delivery by Julie Yooscience, business, and innovation in pharma with Vas Narasimhan, Jorge Conde, Vijay Pande, and Sonal Chokshion hacks of all kinds:https://a16z.com/tag/hacked/
This is the 13th episode of 16 Minutes, our weekly-ish news show where we quickly cover the top headlines of the week, the a16z Podcast way: what’s real, what’s hype from our vantage point in tech. This week, we cover the following news -- with a16z experts general partner Connie Chan and D'arcy Coolican from the consumer team, and former CSO/ a16z security operating partner Joel de la Garza -- in conversation with Sonal Chokshi:OK Boomer meme and meaning -- What makes this meme news, given current and coming tech trends around meme-to-merchandise, ecommerce, video, app design, the future of social... and the overall zeitgeist between generations and cultural transitions?fraud in gaming microtransactions/ trading -- Is money laundering really happening through gaming microtransactions? What to make of Valve's recent restriction that Counter-Strike: Global Offensive container keys cannot be traded or sold on the Steam marketplace because they are now "believed to be fraud-sourced" by worldwide fraud networks?Relevant/ related links:on Ok Boomer:on ecommerce as video's killer app by Connie Chan & Avery Segalon short-form video and the rise of AI-based consumer apps by Connie Chanon when advertising isn't enough, and the shift from "eyeballs" to "wallets" by Connie Chanon design by livestream (as well as other trends from China) by Connie Chanon memes and livestreaming in China with Connie Chan, Christina Xu, and Sonal Chokshion the rise of the super app by Connie Chanon gaming economies:on crypto and new business models for gaming with Kevin Chou, Chris Dixon, and Sonal Chokshicredits: @linzrinzz on TikTok
This is the 11th episode of 16 Minutes, our weekly news show where we quickly cover the top headlines of the week, the a16z Podcast way: what’s real, what’s hype from our vantage point in tech. This week, we cover the following news -- with a16z experts managing partner Scott Kupor and general partner in fintech Angela Strange, respectively, in conversation with Sonal Chokshi:crypto & regulation/policy updates from the SEC and IRS -- including the SEC releasing an announcement that it settled charges for an unregistered ICO, and the IRS' issuing guidance (in the form of a revenue ruling and answers to FAQs) on tax treatment for hard forks and air drops;ATM fees at record highs -- where it was reported that it now costs ~$4.72 (vs. $1.97 in 1998, as tracked by Bankrate.com) to withdraw money from ATMs not owned by one's bank, which disproportionately falls on low-income people in neighborhoods banks tend to avoidFor relevant background/ related links:on crypto & regulation:"Kik and the SEC: What's Going on and What Does It Mean for Crypto?" by Katie Haun"Analogies, the Big Picture, and Considerations for Regulating Crypto" by Scott Kupor & Sonal Chokshion ATM fees and "banking the unbanked":"The Next 3 Billion in Financial Services" by Angela Strange---The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation.This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments for which the issuer has not provided permission for a16z to disclose publicly as well as unannounced investments in publicly traded digital assets) is available at https://a16z.com/investments/.Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.
This is the 11th episode of 16 Minutes, a weekly show where we quickly cover the top headlines of the week, the a16z Podcast way: why are these topics in the news; what’s real, what’s hype -- from our vantage point in tech.This week, we do a 20-ish minute deep-dive on CRISPR, to tease apart the FUD from the facts given a bunch of recent news (not research!) around the gene-editing platform. The news implications range from policy to practice:At the end of July, one of the first laws to directly regulate CRISPR was signed in the state of California by Governor Gavin Newsom, making it illegal for "gene therapy" kits to be sold, unless they have a clear warning label that the kit is "not for self-administration” -- this policy may affect future "biohacking"... but also, such kits don't really exist yet!At the end of August, the Alliance for Regenerative Medicine (ARM, an TKTK) released a Therapeutic Developers’ Statement of Principles for the use of gene editing in therapeutic applications -- endorsed by 13 of the most active companies in the field -- while it supports somatic cell editing, it also asserts that germline gene editing "is currently inappropriate in human clinical settings".The above news is also relevant given news of/ the scandal from earlier this year (first revealed by MIT Technology Review) around "CRISPR babies" with germline edits born in China;Meanwhile, clinical trials for CRISPR are coming of age, with the first publicly identified CRISPR patient (treating sickle cell disease) and the first CRISPR study inside the body (for LCA, the most common cause of inherited childhood blindness); how do these show pacing and containment of risks (somatic cell, monogenetic phenotypes, ex vivo, etc.)?Finally, how does all this news affect innovation in gene therapies and other applications? When it comes to engineering the genome -- including tech challenges and startup opportunities -- what might we  borrow from the history of innovation here? If CRISPR is not a single tool or set of proteins but a platform, what becomes possible? General partner Jorge Conde and partner Andy Tran, both of the a16z bio team, share their thoughts on all this and more with host Sonal Chokshi in this episode of 16 Minutes.
Our news podcast, 16 Minutes -- where we quickly cover the top headlines of the week, the a16z way (why are these topics in the news; what's real, what's hype from our vantage point of tech trends) -- is now only available as its own show feed, separately from the main a16z Podcast... so be sure to subscribe wherever you get your podcasts if you want our weekly news & tech take!This is the tenth episode of the show, and this week we cover a variety of topics with the following a16z experts:Amazon Care healthcare news this week that they're now providing a virtual medical clinic for employees, initially in Seattle, using telemedicine and in-home visits; what does their delivering healthcare actually mean for both incumbents and startups... and the future of medicine? -- with Julie Yoo and Jorge CondeOculus Connect 6, Facebook's annual developer event, where there were a number of announcements about devices, content, and more that could be key to the evolution of virtual reality (VR) and augmented reality (AR) -- with Chris DixonGoogle quantum supremacy claim, as shared in a paper with/via NASA; what's fact, what's fiction about it; what does it actually mean (or not mean) for cryptography and other applications; and where are we, really, in quantum computing? -- with Vijay Pande...hosted by Sonal Chokshi.---The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation.This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments for which the issuer has not provided permission for a16z to disclose publicly as well as unannounced investments in publicly traded digital assets) is available at https://a16z.com/investments/.Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.
This is episode #9 of our news show, 16 Minutes, where we quickly cover recent headlines of the week, the a16z way -- why they’re in the news; why they matter from our vantage point in tech -- and share our experts’ views on the trends involved.This week we do a short but deep dive to tease apart the FUD from the facts on all the phone hacks of late (also, arguably, one of the worst years on record for certain device manufacturers) -- given the following news:Just this week, the FBI’s Cyber Division released a notification to private industry on “Cyber Criminals Use Social Engineering and Technical Attacks to Circumvent Multi-Factor Authentication”;Last week, a telecom security firm reported a vulnerability called “Simjacker” where SMS containing spyware-like code "takes over" a phone's SIM card in order to retrieve and perform sensitive commands, regardless of platform or device;Over the past month, Google and Apple have been going back and forth over a post the former released, “A very deep dive into iOS Exploit chains found in the wild”, where a small collection of hacked websites were using iPhone zero-day vulnerabilities to target China's Uyghur Muslim community (though Google is not the one who revealed the specific websites, Apple did confirm it in their response a week later) -- what do we make of this exchange; of the fact that zero-day hacks are now more expensive on Android than on Apple; and of Apple's ethos when it comes to a third-party ecosystem for security?Finally, how should we think about phone authentication overall when it comes to security, and what can we do to secure ourselves? Our a16z experts -- general partner Martin Casado and former chief security officer/ operating partner for security Joel de la Garza -- share their thoughts on all this and more with host Sonal Chokshi, in this episode of 16 Minutes.---The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation.This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments for which the issuer has not provided permission for a16z to disclose publicly as well as unannounced investments in publicly traded digital assets) is available at a16z.com/investments.Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see a16z.com/disclosures for additional important information.
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Cliff Russell

love your show :0)

Jan 12th
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