BaladoCritique - club de lecture médical

Dans cette 80e baladodiffusion, les Drs Mathieu Labossière et Alexandre Mutchmore discutent de thromboprophylaxie en chirurgie orthopédique, en plus de réviser la littérature médicale d’août 2026.   Quiz clinique (2 min 05), présentation principale (2 min 38), critique (21 min 51), retour sur le cas clinique (31 min 27), autres articles (32 min 50), réponse au quiz clinique (36 min 19).   Référence principale :   Shivakumar S, Matino D, Zukor D, Kahn SR, Vincent G, Mundi R, et al. Rivaroxaban Then Aspirin vs. Aspirin Alone after Total Hip or Knee Arthroplasty. N Engl J Med. 2026. Epub 2026/07/12. doi: 10.1056/NEJMoa2603649. PubMed PMID: 42437501.   Articles associés :   The Pulmonary Embolism Prevention (PEP) Trial Collaborative Group. Prevention of pulmonary embolism and deep vein thrombosis with low dose aspirin: Pulmonary Embolism Prevention (PEP) trial. Lancet 2000;355:1295-302. PubMed PMID: 10776741.   Anderson DR, Dunbar MJ, Bohm ER, et al. Aspirin versus low-molecular-weight heparin for extended venous thromboembolism prophylaxis after total hip arthroplasty: a randomized trial. Ann Intern Med. 2013;158(11):800-6. PubMed PMID: 23732713.   Anderson DR, Dunbar M, Murnaghan J, Kahn SR, Gross P, Forsythe M, et al. Aspirin or Rivaroxaban for VTE Prophylaxis after Hip or Knee Arthroplasty. N Engl J Med. 2018;378(8):699-707. PubMed PMID: 29466159.   Anderson DR, Morgano GP, Bennett C, Dentali F, Francis CS, Garcia DA et al. American Society of Hematology 2019 guidelines for management of venous thromboembolism: prevention of venous thromboembolism in surgical hospitalized patients. Blood Adv 2019;3(23):3898–3944. PubMed PMID: 31794602.   Sidhu VS, Kelly TL, Pratt N, Graves SE, Buchbinder R, Adie S et al. Effect of Aspirin vs Enoxaparin on Symptomatic Venous Thromboembolism in Patients Undergoing Hip or Knee Arthroplasty: The CRISTAL Randomized Trial. JAMA. 2022;328(8):719-727. PubMed PMID: 35997730.   Autres articles d’intérêt récent :   Heerspink HJL, Neuen BL, Agarwal R, Cherney DZI, Lam CSP, Tuttle KR, et al. Finerenone in Persons with Chronic Kidney Disease without Diabetes. N Engl J Med. 2026;395(6):533-45. PubMed PMID: 42246672.   Colson AE, Kumar PN, Ruane PJ, Chetchotisakd P, Ratanasuwan W, Liberty A, et al. Switch to once-weekly, single-tablet islatravir-lenacapavir from daily standard of care for HIV-1 (ISLEND-2): a multicentre, randomised, open-label, active-controlled, phase 3 non-inferiority trial. Lancet. 2026;408(10557):821-32. PubMed PMID: 42586113.   Stone JH, Buttgereit F, Saraux A, Schmidt WA, Dejaco C, Spiera R, et al. Phase 3 Trial of Secukinumab in Polymyalgia Rheumatica. N Engl J Med. 2026;395(7):637-47. PubMed PMID: 42234540.   Akerboom B, Martens ESL, Stals MAM, Brouwer RE, Coppens M, Costantino G, et al. YEARS Algorithm for Diagnosis of Suspected Pulmonary Embolism in Patients With Cancer: A Randomized Clinical Trial. JAMA. 2026;336(8):655-63. PubMed PMID: 42437322.   Guides de pratique :   Prabhakaran S, Gonzalez NR, Zachrison KS, Adeoye O, Alexandrov AW, Ansari SA, et al. 2026 Guideline for the Early Management of Patients With Acute Ischemic Stroke: A Guideline From the American Heart Association/American Stroke Association. Stroke. 2026;57(8):e316-e436. PubMed PMID: 41582814.   Walsh MN, Kober L, Sliwa K, Adamo M, Agarwal A, Banerjee A, et al. AHA/ACC/ESC/WHF Expert Consensus Document: Second Universal Definition of Heart Failure (2026). Circulation. 2026;154(7):e279-e93. PubMed PMID: 42366997.   Référence du quiz clinique :   Vaglio A, Peyronel F, Bajema IM, Pegoraro F. Retroperitoneal fibrosis. Lancet. 2026;408(10555):649-664. PubMed PMID: 41905382.

Dans cette 79e baladodiffusion, les Drs Luc Lanthier et Giulia Pool discutent d’une nouveauté thérapeutique en cancer du pancréas, en plus de réviser la littérature médicale de mai, juin et juillet 2026.   Quiz clinique (2 min 05), présentation principale (2 min 35), critique (22 min 32), retour sur le cas clinique (28 min 04), autres articles (29 min 32), réponse au quiz clinique (36 min 35).   Référence principale :   O’Reilly EM, Wainberg ZA, Hendifar AE, Borad MJ, Pietrantonio F, Pant S, et al. Daraxonrasib or Chemotherapy in Previously Treated Metastatic Pancreatic Cancer. N Engl J Med. 2026;395(4):325-37. PubMed PMID: 42223072.   Articles associés :   Teede HJ, Khomami MB, Morman R, Laven JSE, Joham AE, Costello MF, et al. Polyendocrine metabolic ovarian syndrome, the new name for polycystic ovary syndrome: a multistep global consensus process. Lancet. 2026;407(10545):2329-39. PubMed PMID: 42119588.   Stoop TF, Javed AA, Oba A, Koerkamp BG, Seufferlein T, Wilmink JW, et al. Pancreatic cancer. Lancet. 2025;405(10485):1182-202. PubMed PMID: 40187844.   Der CJ, Yeh JJ. Advances in RAS Therapeutics for Pancreatic Cancer. N Engl J Med. 2026;394(18):1857-1861. PubMed PMID: 42090797.   Wolpin BM, Park W, Garrido-Laguna I, Spira A, Starodub A, Sommerhalder D, et al. Daraxonrasib in Previously Treated Advanced RAS-Mutated Pancreatic Cancer. N Engl J Med. 2026;394(18):1790-802. PubMed PMID: 42090791.   Sivakumar S. Breaking the RAS Barrier in Pancreatic Cancer. N Engl J Med. 2026;395(4):400-1. PubMed PMID: 42485631.   Aronchik I, Kar S, Zhuang Y, Ahler E, Lai LP, Seshadri V, et al. Acquired resistance to the RAS(ON) multi-selective inhibitor daraxonrasib guides rational combination therapy strategies in pancreatic cancer. Nat Med. 2026;32(8):2865-77. PubMed PMID: 42581230.   Autres articles d’intérêt récent :   Rosenfield K, Klok FA, Piazza G, Sharp ASP, Ni Ainle F, Jaff MR, et al. Ultrasound-Facilitated, Catheter-Directed Fibrinolysis for Acute Pulmonary Embolism. N Engl J Med. 2026;394(20):1979-90. PubMed PMID: 41910345.   Cummings JL, Atri A, Sano M, Zetterberg H, Scheltens P, Knop FK, et al. Efficacy and safety of oral semaglutide 14 mg (flexible dose) in early-stage symptomatic Alzheimer’s disease (evoke and evoke+): two phase 3, randomised, placebo-controlled trials. Lancet. 2026;407(10544):2167-79. PubMed PMID: 41865758.   Hayden FG, Shinkai M, Clark TW, Luetkemeyer AF, Sax PE, Hanage WP, et al. Ensitrelvir for Covid-19 Postexposure Prophylaxis in Household Contacts. N Engl J Med. 2026;394(19):1905-15. PubMed PMID: 42127390.   Houston BL, McIsaac DI, Breau RH, Kanji S, Greenstreet P, Andrews M, et al. Hospital Policy of Tranexamic Acid to Reduce Transfusion in Major Noncardiac Surgery. N Engl J Med. 2026;394(24):2419-28. PubMed PMID: 42267805.   Hou J, Lim SG, Buti M, Yuen MF, Gane E, Lampertico P, et al. Phase 3 Results of Bepirovirsen Treatment for Chronic Hepatitis B Virus Infection. N Engl J Med. 2026;394(24):2395-406. PubMed PMID: 42206582.   Wazni OM, Chun KRJ, Nair DG, Anic A, Duytschaever M, Chrispin J, et al; AVANT GUARD Study Investigators. Pulsed Field Ablation as Initial Therapy for Persistent Atrial Fibrillation. N Engl J Med. 2026;394(24):2407-2418. PubMed PMID: 42041224.   Doshi SK, Kar S, Nair DG, Waggoner T, Agarwal H, Moussavian M, et al. Left Atrial Appendage Closure or Anticoagulation for Atrial Fibrillation. N Engl J Med. 2026;394(21):2083-94. PubMed PMID: 41910347.   Staphylococcus aureus Network Adaptive Platform Trial G, Lee TC, Barina LA, Walls G, Goodman AL, Yahav D, et al. Cefazolin for Methicillin-Susceptible Staphylococcus aureus Bacteremia. N Engl J Med. 2026;394(23):2329-39. PubMed PMID: 42308484.   Staphylococcus aureus Network Adaptive Platform (SNAP) Trial Group. Benzylpenicillin versus flucloxacillin or cloxacillin for the treatment of penicillin-susceptible Staphylococcus aureus bacteraemia (SNAP): an international, multicentre, open-label, non-inferiority randomised controlled trial. Lancet. 2026;408(10550):141-152. PubMed PMID: 42309115.   Nathan SD, Smith P, Deng C, King CS, De Salvo M, Weigt SS, et al. Phase 3 Trials of Inhaled Treprostinil for Idiopathic Pulmonary Fibrosis. N Engl J Med. 2026;395(2):115-26. PubMed PMID: 42149993.   Guides de pratique :   Smolen JS, Edwards CJ, Konzett V, Laskou F, Aletaha D, Caporali R, et al. EULAR recommendations for the management of rheumatoid arthritis with synthetic and biologic disease-modifying antirheumatic drugs: 2025 update. Ann Rheum Dis. 2026;85(6):991-1009. PubMed PMID: 41826212.   Peery AF, Strate LL, Stollman N, Mankaney G, Chang JW, Grover S. ACG Clinical Guideline: Colonic Diverticulitis. Am J Gastroenterol. 2026;121(7):1549-61. PubMed PMID: 42390126.   Writing Committee M, Ndumele CE, Rodriguez F, Dixon DL, Khan SS, Mukherjee D, et al. 2026 AHA/ACC/ADA/ASN Guideline for the Prevention, Detection, Evaluation, and Management of Cardiovascular-Kidney-Metabolic Syndrome: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Circulation. 2026;154(4):e50-e158. PubMed PMID: 42263157.   Références du quiz clinique :   Richert Q, Miller N, Cameron S, Barr B, Nkosi J, Sharma A. Updates on Rhabdomyolysis: A Clinically Oriented Narrative Review. Chest. 2026;170(1):128-36. PubMed PMID: 41619932.   Cabral BMI, Edding SN, Portocarrero JP, Lerma EV. Rhabdomyolysis. Dis Mon. 2020;66(8):101015. PubMed PMID: 32532456.

Dans cette 78e baladodiffusion, les Drs Luc Lanthier et Pierre-Nicolas Perron discutent de traitement intensif de la dyslipidémie, en plus de réviser la littérature médicale d’avril 2026.   Quiz clinique (1 min51), présentation principale (2 min 23), critique (16 min 30), retour sur le cas clinique (22 min 25), autres articles (24 min 32), réponse au quiz clinique (27 min 32).   Référence principale :   Lee YJ, Lee SJ, Kim JW, Lee SH, Kim GS, Park JH, et al; Ez-PAVE Investigators. Intensive LDL Cholesterol Targeting in Atherosclerotic Cardiovascular Disease. N Engl J Med. 2026;394(14):1365-1375. PubMed PMID: 41910315.   Articles associés :    Probstfield JL, Branch KRH. Paving the Road toward Targeted Lipid Lowering. N Engl J Med. 2026 Apr 9;394(14):1443-1444. PubMed PMID: 41910324.   Mach F, Koskinas KC, Roeters van Lennep JE, Tokgözoğlu L, Badimon L, Baigent C, et al; ESC/EAS Scientific Document Group. 2025 Focused Update of the 2019 ESC/EAS Guidelines for the management of dyslipidaemias. Eur Heart J. 2025;46(42):4359-4378. PubMed PMID: 40878289.   Marston NA, Bohula EA, Bhatia AK, De Ferrari GM, Leiter LA, Nicolau JC, et al; VESALIUS-CV Investigators. Evolocumab to Reduce First Major Cardiovascular Events in Patients Without Known Significant Atherosclerosis and With Diabetes: Results From the VESALIUS-CV Trial. JAMA. 2026;335(16):1400-1407. PubMed PMID: 41903215.   Cannon CP, Braunwald E, McCabe CH, Rader DJ, Rouleau JL, Belder R, Joyal SV, Hill KA, Pfeffer MA, Skene AM; Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis in Myocardial Infarction 22 Investigators. Intensive versus moderate lipid lowering with statins after acute coronary syndromes. N Engl J Med. 2004;350(15):1495-504. PubMed PMID: 15007110.   LaRosa JC, Grundy SM, Waters DD, Shear C, Barter P, Fruchart JC, et al; Treating to New Targets (TNT) Investigators. Intensive lipid lowering with atorvastatin in patients with stable coronary disease. N Engl J Med. 2005;352(14):1425-35. PubMed PMID: 15755765.   Cannon CP, Blazing MA, Giugliano RP, McCagg A, White JA, Theroux P, et al; IMPROVE-IT Investigators. Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes. N Engl J Med. 2015;372(25):2387-97. PubMed PMID: 26039521.   Sabatine MS, Giugliano RP, Keech AC, Honarpour N, Wiviott SD, Murphy SA, Kuder JF, Wang H, Liu T, Wasserman SM, Sever PS, Pedersen TR; FOURIER Steering Committee and Investigators. Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease. N Engl J Med. 2017;376(18):1713-1722. PubMed PMID: 28304224.   Schwartz GG, Steg PG, Szarek M, Bhatt DL, Bittner VA, Diaz R, et al; ODYSSEY OUTCOMES Committees and Investigators. Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome. N Engl J Med. 2018;379(22):2097-2107. PubMed PMID: 30403574.   Autres articles d’intérêt récent :    Landmesser U, Skurk C, Kirchhof P, Lewalter T, Hartung J, Rroku A, et al; CLOSURE-AF Trial Investigators. Left Atrial Appendage Closure or Medical Therapy in Atrial Fibrillation. N Engl J Med. 2026;394(13):1270-1280. PubMed PMID: 41849741.   Choi KH, Kang D, Kim W, Doh JH, Kim J, Park YH, et al; SMART-DECISION Investigators. Discontinuation of Beta-Blocker Therapy after Myocardial Infarction. N Engl J Med. 2026;394(13):1302-1312. PubMed PMID: 41910427.   Sharma M, Dong Q, Hirano T, Kasner SE, Saver JL, Masjuan J, et al; OCEANIC-STROKE Investigators. Asundexian for Secondary Stroke Prevention. N Engl J Med. 2026;394(15):1467-1479. PubMed PMID: 41985132.   Butler CC, Pinto AD, Harris V, Holmes J, Rahman NM, Cureton L, et al; PANORAMIC Trial and CanTreatCOVID Trial Collaborative Groups. Oral Nirmatrelvir-Ritonavir for Covid-19 in Higher-Risk Outpatients. N Engl J Med. 2026;394(16):1583-1594. PubMed PMID: 42019019.   Guides de pratique :    Prescott HC, Antonelli M, Alhazzani W, et al. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2026. Crit Care Med. 2026;54(4):725-812. PubMed PMID: 41869847.   Blumenthal RS, Morris PB, Gaudino M, et al. 2026 ACC/AHA/AACVPR/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Dyslipidemia: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Circulation. 2026;153(17):e1154-e1276. PubMed PMID: 41824552.   Références du quiz clinique :   Öberg J, Buchwald P, Nilsson A, Nilson B, Inghammar M. Risk and prognosis of colorectal cancer following bacteraemia with Streptococcus bovis–Streptococcus equinus complex: A Swedish nationwide retrospective cohort study. Epidemiol Infect. 2025;154:e2. PubMed PMID: 41449806.   Abdulamir AS, Hafidh RR, Abu Bakar F. The association of Streptococcus bovis/gallolyticus with colorectal tumors: the nature and the underlying mechanisms of its etiological role. J Exp Clin Cancer Res. 2011;30(1):11. PubMed PMID: 21247505.  

Dans cette 77e baladodiffusion, les Drs Alexandre Mutchmore et Geneviève LeTemplier discutent du traitement de l’embolie pulmonaire, en plus de réviser la littérature médicale de mars 2026.   Quiz clinique (2 min 04), présentation principale (2 min 50), critique (21 min 43), retour sur le cas clinique (31 min 08), autres articles (33 min 45), réponse au quiz clinique (38 min 00).   Référence principale :   Castellucci LA, Chen VM, Kovacs MJ, Lazo-Langner A, Greenstreet P, Kahn S, et al; COBRRA Trial Investigators. Bleeding Risk with Apixaban vs. Rivaroxaban in Acute Venous Thromboembolism. N Engl J Med. 2026;394(11):1051-1060. PubMed PMID: 41812192.   Articles associés :    Moores LK. The COBRRA Trial – Ending the Venous Thromboembolism Safety Toss-up. N Engl J Med. 2026;394(11):1123-1124. PubMed PMID: 41812199.   EINSTEIN Investigators; Bauersachs R, Berkowitz SD, Brenner B, Buller HR, Decousus H, Gallus AS, et al. Oral rivaroxaban for symptomatic venous thromboembolism. N Engl J Med. 2010;363(26):2499-510. PubMed PMID: 21128814.   Agnelli G, Buller HR, Cohen A, Curto M, Gallus AS, Johnson M, et al; AMPLIFY Investigators. Oral apixaban for the treatment of acute venous thromboembolism. N Engl J Med. 2013;369(9):799-808. PubMed PMID: 23808982.   Stevens SM, Woller SC, Baumann Kreuziger L, Bounameaux H, Doerschug K, Geersing GJ, et al. Executive Summary: Antithrombotic Therapy for VTE Disease: Second Update of the CHEST Guideline and Expert Panel Report. Chest. 2021;160(6):2247-2259. PubMed PMID: 34352279.   Ortel TL, Neumann I, Ageno W, Beyth R, Clark NP, Cuker A, et al. American Society of Hematology 2020 guidelines for management of venous thromboembolism: treatment of deep vein thrombosis and pulmonary embolism. Blood Adv. 2020 ;4(19):4693-4738. PubMed PMID: 33007077.   Autres articles d’intérêt récent :    Heerspink HJL, Birkenfeld AL, Cherney DZI, Colhoun HM, Groop PH, Ji L, Jongs N, Mathieu C, Pratley RE, Rosas SE, Rossing P, Skyler JS, Tuttle KR, Lawatscheck R, Brinker M, Scheerer MF, Russell J, Schloemer P, McGill JB; FINE-ONE Investigators. Finerenone in Type 1 Diabetes and Chronic Kidney Disease. N Engl J Med. 2026;394(10):947-957. PubMed PMID: 41780000.   Azizi M, Brown JM, Dwyer JP, Flack JM, Jones ESW, Kurlyandskaya R, Li H, Birve F, Lihn AS, Perl S, Schlaich MP, Shibata H, Wang JG, Williams B; Bax24 investigators. Effect of baxdrostat on ambulatory blood pressure in patients with resistant hypertension (Bax24): a phase 3, randomised, double-blind, placebo-controlled trial. Lancet. 2026;407(10532):988-999. PubMed PMID: 41794437.   Zhang Y, Liu Y, Li Y, Li Y, Gu X, Kang JH, Eliassen AH, Wang M, Rimm EB, Willett WC, Hu FB, Stampfer MJ, Wang DD. Coffee and Tea Intake, Dementia Risk, and Cognitive Function. JAMA. 2026;335(11):961-974. PubMed PMID: 41661604.   Rosenstock J, Yabe D, Cox D, Li J, Denning M, Wu WS, Liu R, Zhao Y; ACHIEVE-3 Investigators. Efficacy and safety of once-daily oral orforglipron compared with oral semaglutide in adults with type 2 diabetes (ACHIEVE-3): a multinational, multicentre, non-inferiority, open-label, randomised, phase 3 trial. Lancet. 2026;407(10534):1147-1160. PubMed PMID: 41765029.   Guides de pratique :    Bajaj JS, Jakab SS, Jesudian AB, Rahimi RS, Duarte-Rojo A, Chen PH, Wong RJ, Tapper EB, Tandon P. ACG Clinical Guideline: Hepatic Encephalopathy. Am J Gastroenterol. 2026;121(3):588-618. PubMed PMID: 41773757.   Creager MA, Barnes GD, Giri J, Mukherjee D, Jones WS, Burnett AE, Carman T, Casanegra AI, Castellucci LA, Clark SM, Cushman M, de Wit K, Eaves JM, Fang MC, Goldberg JB, Henkin S, Johnston-Cox H, Kadavath S, Kadian-Dodov D, Keeling WB, Klein AJP, Li J, McDaniel MC, Moores LK, Piazza G, Prenger KS, Pugliese SC, Ranade M, Rosovsky RP, Russo F, Secemsky EA, Sista AK, Tefera L, Weinberg I, Westafer LM, Young MN. 2026 AHA/ACC/ACCP/ACEP/CHEST/SCAI/SHM/SIR/SVM/SVN Guideline for the Evaluation and Management of Acute Pulmonary Embolism in Adults: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Circulation. 2026;153(12):e977-e1051. PubMed PMID: 41712677.   Référence du quiz clinique :   Abramson BL, Al-Omran M, Anand SS, Albalawi Z, Coutinho T, de Mestral C, et al. Canadian Cardiovascular Society 2022 Guidelines for Peripheral Arterial Disease. Can J Cardiol. 2022;38(5):560-587. PubMed PMID: 35537813.

Dans cette 76e baladodiffusion, les Drs Alexandre Mutchmore et Luc Lanthier discutent de diagnostic de la thrombose veineuse profonde, en plus de réviser la littérature médicale de janvier et février 2026.   Quiz clinique (1 min 45), présentation principale (2 min 15), critique (23 min 10), retour sur le cas clinique (30 min 25), autres articles (31 min 48), réponse au quiz clinique (36 min 55).   Référence principale :   Le Gal G, Robert-Ebadi H, Thiruganasambandamoorthy V, Moustafa F, Penaloza A, Catella J, et al. Age-Adjusted D-Dimer Cutoff Levels to Rule Out Deep Vein Thrombosis. JAMA. 2026;335(5):416-24. PubMed PMID: 41490105.   Articles associés :    Righini M, Van Es J, Den Exter PL, Roy PM, Verschuren F, Ghuysen A, et al. Age-adjusted D-dimer cutoff levels to rule out pulmonary embolism: the ADJUST-PE study. JAMA. 2014;311(11):1117-24. PubMed PMID: 24643601.   Ujueta F, Piazza G. Like a Fine Wine-Aging the D-Dimer to Improve Value and Clinical Efficiency. JAMA. 2026;335(5):403-4. PubMed PMID: 41490683.   Lim W, Le Gal G, Bates SM, Righini M, Haramati LB, Lang E, et al. American Society of Hematology 2018 guidelines for management of venous thromboembolism: diagnosis of venous thromboembolism. Blood Adv. 2018;2(22):3226-56. PubMed PMID: 30482764.   https://thrombosiscanada.ca/hcp/practice/clinical_guides?language=en-ca&guideID=DEEPVEINTHROMBOSISDIAGNOSIS   https://acforum.org/web/resource_files/1772710804-36404.pdf   Autres articles d’intérêt récent :    Lok CE, Farkouh M, Hemmelgarn BR, Moist LM, Polkinghorne KR, Tomlinson G, et al. Fish-Oil Supplementation and Cardiovascular Events in Patients Receiving Hemodialysis. N Engl J Med. 2026;394(2):128-37. PubMed PMID: 41201837.   Verma A, Birnie DH, Jiang C, Heidbuchel H, Hindricks G, Kirchhof P, et al. Antithrombotic Therapy after Successful Catheter Ablation for Atrial Fibrillation. N Engl J Med. 2026;394(4):323-32. PubMed PMID: 41211931.   Wong CX, Cheung CC, Montenegro G, Oo HH, Pena IJ, Tang JJ, et al. Caffeinated Coffee Consumption or Abstinence to Reduce Atrial Fibrillation: The DECAF Randomized Clinical Trial. JAMA. 2026;335(4):317-25. PubMed PMID: 41206802.   Marston NA, Bergmark BA, Alexander VJ, Prohaska TA, Kang YM, Moura FA, et al. Olezarsen for Managing Severe Hypertriglyceridemia and Pancreatitis Risk. N Engl J Med. 2026;394(5):429-41. PubMed PMID: 41211918.   Navar AM, Mikhailova E, Catapano AL, Banka P, Blom DJ, Cadena A, et al. A Placebo-Controlled Trial of the Oral PCSK9 Inhibitor Enlicitide. N Engl J Med. 2026;394(6):529-39.    Lee SJ, Yu HT, Lee YJ, Lee SH, Heo JH, Ahn SG, et al. Therapy for Atrial Fibrillation in Patients with Drug-Eluting Stents. N Engl J Med. 2026;394(7):658-68. PubMed PMID: 41211917.   Rana AI, Zheng L, Castillo-Mancilla J, Bao Y, Sieczkarski S, Brooks KM, et al. Cabotegravir plus Rilpivirine for Persons with HIV and Adherence Challenges. N Engl J Med. 2026;394(9):858-71. PubMed PMID: 41707171.   Guides de pratique :    American Diabetes Association Professional Practice Committee for D. Summary of Revisions: Standards of Care in Diabetes-2026. Diabetes Care. 2026;49(1 Suppl 1):S6-S12. PubMed PMID: 41358896.   Andrade JG, Joza J, Chew DS, Ayala-Paredes F, Bennett MT, Essebag V, et al. The Canadian Cardiovascular Society/Canadian Heart Rhythm Society Comprehensive Guidelines for the Selection, Implantation, and Management of Patients With Cardiac Implantable Electronic Devices. Can J Cardiol. 2026;42(1):1-68. PubMed PMID: 41539743.   Babitt JL, Berns JS, Bozkurt B, Cheung Khedairy RS, Cuevas Y, Effa EE, et al. Executive Summary of the KDIGO 2026 Clinical Practice Guideline for the Management of Anemia in Chronic Kidney Disease (CKD). Kidney Int. 2026;109(1):44-56. PubMed PMID: 41485807.   Mahadevan U, Seow CH, Barnes EL, Chaparro M, Flanagan E, Friedman S, et al. Global Consensus Statement on the Management of Pregnancy in Inflammatory Bowel Disease. Am J Gastroenterol. 2026;121(1):31-79. PubMed PMID: 40862489.   Références du quiz clinique :   Sconfienza E, Tetti M, Forestiero V, Veglio F, Mulatero P, Monticone S. Prevalence of Functioning Adrenal Incidentalomas: A Systematic Review and Meta-analysis. J Clin Endocrinol Metab. 2023;108(7):1813-1823. PubMed PMID: 36718682.   Fassnacht M, Tsagarakis S, Terzolo M, Tabarin A, Sahdev A, Newell-Price J, Pelsma I, Marina L, Lorenz K, Bancos I, Arlt W, Dekkers OM. European Society of Endocrinology clinical practice guidelines on the management of adrenal incidentalomas, in collaboration with the European Network for the Study of Adrenal Tumors. Eur J Endocrinol. 2023;189(1):G1-G42. PubMed PMID: 37318239.   Kebebew E. Adrenal Incidentaloma. N Engl J Med. 2021;384(16):1542-1551. PubMed PMID: 33882207.