Chemist Confessions

Why popular over-the-counter ingredients might be falling short, how prescription options like low-dose tretinoin and spironolactone fit into the picture, and what a realistic, long-term management game plan looks like for aging, irritation-prone skin. Tune in to cut through the marketing noise and get the hard science on managing adult acne! 00:00 | HOT TAKE! 02:20 | The Four Biological Culprits of Breakouts 06:50 | Age Brackets & Defining Post-Adolescent Acne 09:16 | Persistent vs. Late-Onset Acne & Lifestyle Factors 11:37 | Spotlight on The Specialist Acid Booster 15:35 | Men vs. Women: Breaking Down the Prevalence Stats 23:23 | Hormones, DHT, and Systemic Factors 31:47 | Clinical Deep Dive: Low-Dose Tretinoin Efficacy 39:04 | Modern Retinoids Beyond Tretinoin 44:42 | Hot Takes on Salicylic Acid and Azelaic Acid   #skincarescience #acnecare

We spent three years developing our own mask tech, and it’s finally here! Meet CryoGoo, our  lattice jelly peel-off mask, built to get around the material limits of traditional masks.   To celebrate, we are going down a mask tech rabbit hole with everyone. In this episode,we break down what a face mask actually needs to do: occlusion, hydration, and active delivery. Then we put fabric sheet masks, bio-cellulose, hydrogel, PVA wrapping masks, and alginate modeling masks to the test, covering the real pros, cons, and performance of each. And of course, last but not least, we go through what makes our CryoGoo different from everyone else.   LINKS & PRODUCTS Chemist Confessions CryoGoo Jelly Peel-Off Mask: https://chemistconfessions.com/products/cryogoo-cooling-jelly-peel-off-mask Biodance Bio-Collagen Real Deep Mask: https://go.shopmy.us/p-95630015 Revision Skincare Biocellulose Mask: https://go.shopmy.us/p-95631114 Medicube Collagen Night Wrapping Mask: https://go.shopmy.us/p-95630093 Mediheal Derma Modeling Mask: https://go.shopmy.us/p-95630988 CC Podcast Products: https://shopmy.us/collections/4698294 Shop Favorites: https://shopmy.us/chemistconfessions #skincarescience #sheetmask #cosmeticchemistry #newskincareproduct  

In this special episode, we're joined by Rita Silva, Acting Director of Scientific Communications at DECIEM, for a deep dive into the science behind The Ordinary's popular peptide serums. From Multi-Peptide and Matrixyl to Argireline and the latest plant-derived growth factors, we're getting into the formulation history, clinical research, and what these products can realistically do for your skin. And of course, we have to tackle some of your biggest peptide questions. Can you mix copper peptides with vitamin C? Are peptide serums worth adding to a retinoid routine? And where should a peptide beginner even start? #skincarescience #sponsored #peptides #cosmeticchemist

PLEASE NOTE: In this episode, the original Skinceuticals CE Ferulic formula with only 15% ascorbic acid, 1% tocopherol, and 0.5% ferulic acid was tested for this episode. We dive into part two of our vitamin C series by putting popular C E Ferulic dupes to the test. Before revealing our side-by-side stability results, we go through a very helpful study from Slovenia examining 41 finished vitamin C products using HPLC testing to compare the quirks of various vitamin C derivatives—including L-ascorbic acid, ascorbyl glucoside, sodium ascorbyl phosphate, and 3-O-ethyl ascorbic acid. Then we go through our 8 week test findings of 7 CE Ferulic dupes and compare them to the mother formula from Skinceuticals. Shop our favorite C E Ferulic Dupes We've Tried Here: https://shopmy.us/collections/40252 Mentioned in Video & Liked! SKINCEUTICALS | C E Ferulic: https://go.shopmy.us/p-362235 TIMELESS SKIN CARE | 20% Vitamin C + E Ferulic Acid Serum: https://go.shopmy.us/p-362237 MAELOVE | The Glow Maker Serum: https://go.shopmy.us/p-362240 DRMTLGY | Vitamin C E + F Serum 30ml: https://go.shopmy.us/p-87127883 EDUCATED MESS | Golden Hour Gold-Stabilized Vitamin C Serum: https://go.shopmy.us/p-87128013 00:00 | Vitamin C Dupes Series Round 3 Overview 01:16 | Slovenian Study: Analyzing 41 Vitamin C Products with HPLC 06:31 | Comparing L-Ascorbic Acid Stability to the Other Vitamin C Derivatives 15:43 | Meet the Contenders: Pricing and Packaging of Popular Dupes 20:15 | Week 0 to Week 8: Accelerated Oven Stability Test Results 24:53 | Pump Disasters, Gas Buildup, and Sedimentation Issues 28:31 | pH Levels and Batch-to-Batch Consistency in Serums 33:23 | Top Affordable C E Ferulic Alternatives We Recommend 35:16 | Final Thoughts on Vitamin C Derivatives and Derivatives Wrap-Up Don't forget to like, subscribe, and drop your favorite mineral SPF in the comments! #30for30 #SunscreenChallenge #SkincarePodcast  

We dive into a science-heavy breakdown of vitamin C formulations, focusing on the recent updates to the gold-standard C E Ferulic serum. We explore the history of L-ascorbic acid efficacy studies dating back to the 1990s by Dr. Pinnell’s lab, highlighting the classic UV-induced erythema protocol used to validate antioxidant skin protection. Then, we analyze emerging clinical data around new CE Ferulic additions: carnosine and dandelion endophytol and discuss the available data to see if the chemists can figure out whether or not this is worth the Skinceuticals price tag.   00:00 | Intro! 03:15 | L-Ascorbic Acid: A Brief Review 12:48 | What is Dandelion Endophytol? 25:00 | Carnosine's Clinical UV MED Study 29:30 | Reviewing Carnosine's Clinical Testing 34:15 | The Challenges of Plant Extracts and Actives 38:30 | Chemists discuss CE Ferulic vs. CE Ferulic 2.0 41:45 | The Chemists' Feelings on Patents