Holistic Investment w Constantin Kogan

Edward Zuckerberg on AI, Dentistry, Oral Health & the Future of HealthcareWhat happens when 50 years of dental experience meets AI, robotics, venture capital, and the future of healthcare?In this episode of Holistic Investments, Constantin Kogan sits down with Dr. Edward Zuckerberg, pioneering dentist, technology adopter, AI advocate, educator, and advisor to entrepreneurs in oral healthcare.Dr. Zuckerberg shares his journey from starting his dental career in Brooklyn to becoming an advocate for transforming dentistry through technology, education, and better integration between oral health and systemic health.𝗜𝗻 𝗧𝗵𝗶𝘀 𝗘𝗽𝗶𝘀𝗼𝗱𝗲00:00 Introduction and Dr. Edward Zuckerberg’s journey01:28 Beyond the Zuckerberg surname03:18 What would surprise his younger self?05:18 Why oral health matters to systemic wellness06:00 What inspired him to become a dentist07:36 The values that shaped his life08:00 Starting his dental career11:00 His first major clinical experience12:30 The lesson that changed his confidence as a dentist14:32 The strangest things found in a patient’s mouth17:03 Dental habits people get wrong17:14 Why daily mouthwash may not be what you think18:58 Why brushing harder can damage your teeth20:07 The one dental tool he would take to a deserted island21:38 A quick lesson on flossing correctly22:16 Should you floss before or after eating?23:11 The technology changing everyday dental care24:06 Why you should wait before brushing after acidic foods25:00 The minimum dental routine everyone should follow25:53 Is chewing gum actually good for your teeth?26:37 The biggest innovations in dentistry27:26 The evolution of dental imaging30:46 The rise of digital X rays32:39 Understanding ROI in dental technology35:27 How AI is transforming dental diagnosis36:53 Can robots replace dentists?37:30 Dental robots already performing procedures40:59 The future of robotic dentistry41:14 Investing in the next generation of dental technology42:25 Replacing X rays with light based imaging43:37 The size of the global dental market44:11 The changing economics of owning a dental practice45:24 Why dental education has become so expensive46:26 What AI can never replace in dentistry46:52 The importance of trust and human connection48:15 Why dental insurance may be hurting the profession52:57 The biggest problems facing dentistry today53:16 Why education is one of dentistry’s biggest challenges54:41 The connection between oral health and systemic health58:33 A patient story that changed his perspective59:35 Oral health during pregnancy1:01:48 The role of P. gingivalis1:04:16 How oral bacteria may affect the body1:05:11 The blood brain barrier and oral health research1:06:49 Oral health and Alzheimer’s research1:08:07 The emerging investment opportunity in oral healthcare1:10:17 Where investors are putting money in dental AI1:11:33 AI powered dental imaging1:12:00 The future of AI in dental practices1:13:45 How entrepreneurs can pitch Dr. Zuckerberg1:14:18 Rapid Fire Wisdom1:15:05 The habit that changed his life1:15:14 What dental schools should teach1:15:42 What is overrated in dentistry?1:15:45 Family, integrity, and legacy1:16:26 The meaning of life1:16:45 Final thoughts𝗗𝗶𝘀𝗰𝗹𝗮𝗶𝗺𝗲𝗿This podcast is for informational and educational purposes only. Nothing discussed in this episode should be construed as legal, tax, investment, financial, medical, or other professional advice. Views expressed by guests are their own and do not necessarily represent the views of Holistic Investments or its affiliates. Always conduct your own research and consult an appropriately qualified professional before making any investment, medical, or other decision.

🎧 BLOND:ISH on Music, Energy, Consciousness, Crypto & Creating a Better World | Holistic Investments PodcastWhat if music is more than entertainment? What if it's a technology for shifting consciousness?In this episode of Holistic Investments, Constantin Kogan sits down with world-renowned DJ, producer, entrepreneur, and founder of Abracadabra and Bye Bye Plastic, BLOND:ISH.From her early days in Montreal to performing on the world's biggest stages, BLOND:ISH shares how music, energy, spirituality, community, and technology intersect. We explore the architecture of energy in DJ sets, the future of conscious communities, crypto's role in building aligned ecosystems, environmental activism, breathwork, and the deeper meaning of life itself.Whether you're a DJ, entrepreneur, investor, creator, or seeker, this conversation offers a unique perspective on how frequency, intention, and purpose can shape both individual lives and global culture.⏱️ Timestamps00:00 - Introduction02:08 - Personal story & origin journey07:24 - First concert in Montreal & first performance08:40 - Advice for aspiring DJs09:31 - Preparation techniques before a set11:30 - Energy architecture and reading a crowd14:00 - What is music?15:30 - Understanding the house music genre18:00 - Energy hygiene tools and practices21:00 - $NRG token as an access layer for community26:15 - Abracadabra Church and conscious gatherings28:50 - First impressions of crypto in 201731:20 - Indigo Fund and conscious investing36:47 - Environment, sustainability & Bye Bye Plastic43:00 - The BLOND:ISH dream47:40 - Rapid-fire questions50:20 - Favorite breathwork practice50:40 - Meaning of life52:44 - Book recommendations📚 Books Mentioned📖 Wisdom of the Mystic Masters by Joseph J. Weedhttps://a.co/d/0abtrj2i📖 The World Is Sound: Nada Brahma - Music and the Landscape of Consciousness by Joachim-Ernst Berendthttps://a.co/d/09wQ1zH9🌍 Support Bye Bye PlasticBye Bye Plastic Foundation💚 Learn more about conscious investing and regenerative projects:Indigo Fund🎙️ About Holistic InvestmentsHosted by Constantin Kogan, Holistic Investments explores the intersection of investing, technology, consciousness, entrepreneurship, health, and human potential through conversations with world-class founders, investors, scientists, artists, and visionaries.#BLONDISH #HouseMusic #MelodicHouse #Consciousness #Crypto #Web3 #Breathwork #MusicIndustry #ElectronicMusic #DJLife #HolisticInvestments #Energy #Spirituality #IndigoFund #ByeByePlastic #Abracadabra #Podcast #ConstantinKogan #FutureOfCulture #MusicAndConsciousness

In this sharp and forward looking conversation, Hyunsu Jung, CEO of Hyperion DeFi, joins host Constantin Kogan to explain why Hyperion is not just another crypto treasury, but one of the first publicly traded DeFi native operating companies.From spotting Hyperliquid early and recognizing the utility behind HYPETo building revenue generating on chain business lines around staking, validator economics, and DeFi monetizationTo positioning Hyperion as a public market vehicle for real DeFi exposureThis is a conversation about what happens when a balance sheet becomes a growth engine.Hyunsu Jung Reveals:🚀 Why Hyperion is a DeFi operating company, not just a treasury🧠 What most people still misunderstand about DeFi monetization⚡ Why Hyperliquid created a real business opportunity on chain📈 How Hyperion built multiple revenue streams around HYPE🏦 Why public markets are a massive advantage for DeFi companies💸 How staking, validator commissions, and DeFi monetization work together🔁 Why the triple dip strategy may just be the beginning🌐 Why Hyperliquid could become the blockchain to house all finance📊 What makes Hyperion different from MicroStrategy and other DATs🛠 How the team thinks about risk, deployment, and scaling🔮 Why Hyunsu believes DeFi is still in the earliest innings🌅 What the meaning of life looks like to a 30 year old public company CEO🎯 Watch if you are:• A public market investor trying to understand DeFi native businesses• A crypto investor looking beyond simple treasury models• A founder building in DeFi, infrastructure, or tokenized finance• A trader watching the rise of Hyperliquid• Or someone curious about where on chain financial markets are heading nextThis episode explores why the next phase of DeFi may not look like a protocol, a token, or a treasury alone, but a real operating company built to compound ecosystem growth.“Hyperion is the true DeFi company for Hyperliquid.” “DeFi is just starting.” - Hyunsu JungFollow Hyunsu Jung and Hyperion DeFi:🌐 Hyperion DeFi: https://hyperiondefi.com💻 LinkedIn: https://www.linkedin.com/company/hyperion-defi/✖️ X: https://x.com/hyperiondefi👤 Hyunsu on X: https://x.com/hyunsujung_✉️ For business inquiries: [email protected]🎧 Listen to the full podcast here:https://anchor.fm/constantinkoganFollow me on socials:🌐 Website: https://ckogan.com📲 Telegram: https://t.me/constantinkogan📸 Instagram: https://www.instagram.com/constkogan/💻 LinkedIn: https://www.linkedin.com/in/constantin-kogan✖️ X: https://x.com/constkogan🎙 Podcast: https://anchor.fm/constantinkoganTimestamps0:00 - Why Hyperion DeFi is not just another crypto treasury1:22 - Why Hyperliquid created a new kind of public company3:03 - Hyunsu Jung’s background before Hyperion5:31 - What most people still miss about DeFi monetization7:30 - Why Hyperliquid is becoming a serious trading venue9:21 - Breaking down the triple dip strategy12:08 - The five revenue streams behind Hyperion15:11 - How off chain capital connects to on chain DeFi16:23 - The profit model and why execution matters19:25 - What makes Hyperion different from MicroStrategy21:04 - Why Hyperliquid’s numbers are hard to ignore24:25 - Why traditional traders are paying attention now28:06 - How investors can access Hyperion DeFi through public markets30:07 - The Inovia pivot and the investors behind Hyperion32:53 - What could break the model and how risk is managed35:20 - Why Hyperion is all in on Hyperliquid37:39 - HIP4, new market structures, and what comes next39:47 - Inside the team building Hyperion41:04 - Will more DATs launch on Hyperliquid43:57 - Lightning round on HYPE, DeFi, and real alpha47:13 - Hyunsu Jung on meaning, leadership, and building at the right time#HyunsuJung #ConstantinKogan #HyperionDeFi #Hyperliquid #DeFi #Crypto #PublicMarkets #DigitalAssetTreasury #HYPE #Blockchain #HolisticInvestments

In this fascinating and practical conversation, Dmitry Tokarev, founder of Copper and co founder of Bron, joins host Constantin Kogan to break down one of the biggest unsolved problems in crypto: security for real users.From growing up in Siberia and discovering trading at a young age, to building Copper into one of the world’s leading institutional custody firms, and now leading Bron with a mission to bring institutional grade wallet security to retail users.This is a conversation about why crypto still feels dangerous for most people and what it will take to finally fix that.Dmitry Tokarev Reveals:🔐 Why most retail crypto wallets are still dangerously outdated🧠 The real difference between institutional custody and retail self custody🧩 What MPC actually means and why institutions rely on it📱 Why seed phrases should never have been the long term answer🚨 How people are really losing crypto today through phishing, SIM swaps, address poisoning, and physical attacks🛡️ Why Bron was built to remove the biggest security mistakes users make👥 How social recovery and successors can protect users without seed phrases⏳ Why time delays and approval policies matter for serious crypto holders🌍 What the future of crypto custody looks like as more real world assets move on chain⚙️ Why user experience, not just security, is the next big unlock for adoption📚 The book that changed Dmitry’s career path🌅 What peace of mind means to him and how he thinks about life🎯 Watch if you are:• A crypto holder worried about wallet security• A founder building in wallets, custody, or on chain infrastructure• An investor trying to understand where crypto UX still fails• Someone curious about the gap between institutional crypto and retail crypto• Or simply trying to protect yourself better in this spaceThis episode explores why the next breakthrough in crypto may not be a new token or protocol, but a safer way for normal people to actually hold their assets.“Retail should not be forced to understand all this crazy stuff just to stay safe.” - Dmitry Tokarev“If you can lose everything with one mistake, the product is broken.” - Dmitry TokarevLearn more about Bron here: https://go.bron.org/constantinkogan05Follow Dmitry Tokarev and Bron:🌐 Bron: https://bron.org/💻 LinkedIn:https://www.linkedin.com/in/tokarevdmitry/✖️ X: https://x.com/tokarev_d✉️ For business inquiries: [email protected]🎧 Listen to the full podcast here:https://anchor.fm/constantinkoganFollow me on socials:🌐 Website: https://ckogan.com📲 Telegram: https://t.me/constantinkogan📸 Instagram: https://www.instagram.com/constkogan/💻 LinkedIn: https://www.linkedin.com/in/constantin-kogan✖️ X: https://x.com/constkogan🎙 Podcast: https://anchor.fm/constantinkoganTimestamps0:00 - From Siberia to crypto custody pioneer3:20 - Why trading led Dmitry into building products4:52 - The three generations of crypto custody6:42 - What MPC means in simple terms8:29 - Why retail security is still broken11:39 - How Bron removes seed phrase risk15:13 - Social recovery, successors, and inheritance17:39 - How Bron handles real world wallet security19:57 - Why crypto users are now physical targets23:21 - How to protect large holdings from coercion28:58 - The hacks, scams, and attack patterns hurting retail33:38 - Three simple steps to protect yourself today39:17 - Dmitry’s view on the future of on chain assets45:52 - The DeFi risk most users still do not understand58:03 - Dmitry Tokarev on the meaning of life1:00:04 - The book that changed his direction1:02:26 - Where to follow Dmitry and Bron#DmitryTokarev #ConstantinKogan #Bron #Copper #CryptoSecurity #SelfCustody #WalletSecurity #Blockchain #Crypto #DigitalAssets #HolisticInvestments

Jebediah “Joby” Weeks, early Bitcoin pioneer, entrepreneur, and co creator of the iconic Bitcoin logo, joins host Constantin Kogan to share one of the wildest stories in crypto history.From becoming a millionaire at 19 and building disruptive businesses across health, currency, and politics…To experimenting with local money systems before Bitcoin went mainstream…To entering the early crypto frontier through Silk Road, Mt. Gox, Ethereum, mining, and BitClub…This is a conversation about freedom, disruption, and the cost of being early.Joby Weeks Reveals:🟠 How he and his partner designed the Bitcoin logo the world now uses💰 How he became a millionaire at 19🏛 Why he lost faith in the government while building alternative systems🪙 How he created local currencies before Bitcoin🌿 His role in helping legalize cannabis in Colorado⚡️ What it was like buying Bitcoin in the Silk Road era📉 How he lost funds through Silk Road, Mt. Gox, and the DAO fork era🏝 How Liberland and other sovereign experiments entered his story⛏️ How he got involved in large scale Bitcoin mining and BitClub🚨 What happened when federal authorities came after him🔒 What life has been like under more than six years of house arrest without trial🧘 How isolation changed his view of power, success, and the meaning of life🎯 Watch if you are:• Interested in the early history of Bitcoin• Curious about the wild west era of crypto mining• Following the intersection of government power and financial freedom• A founder building in crypto, fintech, or alternative systems• Or someone interested in the psychology of surviving extreme pressureThis episode explores what happens when innovation collides with the state and what it costs to stay standing when the system turns against you.“First they don’t believe in you, then they violently oppose you, and then you win.” — Joby Weeks“Hate is poison you drink thinking it’s going to harm the other person.” — Joby WeeksFollow Joby Weeks:💼 LinkedIn:   / jobyweeks  📸 Instagram:   / jobyweeks18  🌐 Website / Support Site: http://www.freejoby.com✉️ For business inquiries: [email protected]🎧 Listen to the full podcast here: https://anchor.fm/constantinkoganFollow me on socials:🌐 Website: https://ckogan.com📲 Telegram: https://t.me/constantinkogan📸 Instagram:   / constkogan  💻 LinkedIn:   / constantin-kogan  ✖️ X: https://x.com/constkogan🎙 Podcast: https://anchor.fm/constantinkoganTimestamps:00:00 The Bitcoin logo story01:32 The family legacy and the Federal Reserve connection04:09 Freedom, sound money, and why he distrusts government07:39 Becoming a millionaire at 19 and building early companies11:05 Minting gold and silver and the Liberty Dollar chapter19:40 Creating a local currency before Bitcoin23:06 First Bitcoin buy and the early Silk Road era25:02 Mt. Gox, early losses, and the wild west years26:19 Meeting Vitalik and getting into Ethereum early34:01 BitClub, large scale mining, and what came next42:54 Detained and pressured for his private keys43:42 Jail transfers and no trial diesel therapy49:04 Six years of house arrest and life restrictions50:47 FreeJoby.com and the push for public awareness54:17 What this experience changed in him55:49 Meaning of life, love, and staying grounded