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SLAS Technology Authors Talk Tech

Author: Dave Pechter, M.S.M.E.

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We invite you to "get behind the science" with SLAS Technology Editorial Board Member and Podcast Editor Dave Pechter, M.S.M.E. (PerkinElmer, Cambridge, MA) and hear from our featured SLAS Technology authors! This podcast series is a chance for readers to meet the people behind the journal science and hear directly from them about their work, their motivations, as well as the context and potential impact of their work. Watch for a new featured author interview with each published issue!
29 Episodes
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In this episode, podcast host David Pechter invites SLAS Technology featured author Dr. Hossam Ibrahim (University College Dublin) to discuss his research on the dissemination of tumor cells to understand the mechanisms behind cancer metastasis. Tune in to hear how the research team developed a migration assay combining 3D models and a physiologically relevant extracellular matrix. Hear about the unique challenges faced by researchers while orchestrating the application of 3D technologies wit...
Behind the Special Issue: Join podcast host David Pechter as he invites Joseph de Rutte (Partillion Bioscience) to discuss the paper: “Sorting single-cell microcarriers using commercial flow cytometers”. This research was featured in the recent SLAS Technology special issue, Single Cell Analysis Technologies. Listen in as they discuss the unique formation of microscopic, bowl-shaped containers they call nanovials, and the applications of these cell carriers in flow cytometry for functional si...
Join SLAS Podcast Host Dave Pechter as he welcomes R. Graham Cooks, Ph.D. (Purdue University) and Nicolás M. Morato (Purdue University) to discuss their research, featured in the latest Issue of SLAS Technology. They are joined by Nathan P. Coussens, Ph.D. (Frederick National Laboratory for Cancer Research), guest editor of this special issue. Together, they discuss the article “Automated High-Throughput System Combining Small-Scale Synthesis with Bioassays and Reaction Screening”. Thi...
Volume 26 Issue 1, February 2021 Dave Pechter discusses the February SLAS Technology Special Collection AI in Process Automation with Guest Editor Cenk Undey (Amgen), which includes the following papers: Artificial Intelligence Effecting a Paradigm Shift in Drug Development by Masturah Bte Mohd Abdul RashidArtificial Intelligence (AI) to the Rescue: Deploying Machine Learning to Bridge the Biorelevance Gap in Antioxidant Assays by Sunday Olakunle Idowu and Amos Akintayo FatokunDeep Lear...
Volume 25 Issue 6, December 2020 Dave Pechter discusses the December SLAS Technology Special Collection Advances in Technology to Address COVID-19 with Associate Editor Pak Kin Wong (The Pennsylvania State University), which includes Professor Wong's review Advances in Viral Diagnostic Technologies for Combating COVID-19 and Future Pandemics.
Volume 25 Issue 5, October 2020 Dave Pechter discusses with Varun Bhaskar Kothamachu, Ph.D. (Head of Product, Digi.Bio) & Sabrina Zaini (Head of Operations, Digi.Bio) their featured research article, "Role of Digital Microfluidics in Enabling Access to Laboratory Automation and Making Biology Programmable."
Volume 25 Issue 3, June 2020 Dave Pechter discusses with Georges Muller & Yann Barrandon their two featured research articles, "Traceable Impedance-Based Dispensing and Cloning of Living Single Cells" and "Impedance-Based Single-Cell Pipetting." Traceable Impedance-Based Dispensing and Cloning of Living Single Cells: Single-cell cloning is essential in stem cell biology, cancer research, and biotechnology. Regulatory agencies now require an indisputable proof of clonality that current t...
Volume 25 Issue 2, April 2020 Dave Pechter discusses with Agata Blasiak & Theodore Kee regarding their article, "CURATE.AI: Optimizing Personalized Medicine with Artificial Intelligence." The clinical team attending to a patient upon a diagnosis is faced with two main questions: what treatment, and at what dose? Clinical trials’ results provide the basis for guidance and support for official protocols that clinicians use to base their decisions upon. However, individuals rarely de...
Volume 25 Issue 1, February 2020 Dave Pechter discusses with Hideaki Tsutsui & Peter Lillehoj regarding February's Special Issue. Over the last decade, flexible analytical devices have received considerable attention in both academia and industry. Compared to conventional analytical devices which are generally made from rigid materials, such as silicon, glass, and plastics, flexible devices offer several unique advantages, such as simplified fabrication, lower costs, enhanced portability...
Volume 24 Issue 6, December 2019 Dave Pechter discusses with Chao Li the article, "Automated System for Small-Population Single-Particle Processing Enabled by Exclusive Liquid Repellency." Lossless processing and culture of rare cells (e.g., circulating tumor cells, drug-persistent microorganisms) at single-cell level is of great significance in understanding the heterogeneity of carcinogenesis or human pathogenesis caused by microbial infection. Current single-cell isolation techniqu...
SLAS Technology 24.5 October 2019 Professors at Johns Hopkins University, Claire Hur and Deok-Ho Kim, discuss their special issue, "Engineering Innovations for Fundamental Biology and Translational Medicine." In this special issue of SLAS Technology, the editors showcase reviews and original research reports addressing the accuracy in diagnostic and prognostic tests performed on the patient-derived specimen, an emerging technology demand for personalized medicine. Soojung Claire Hur, Ph.D....
Volume 24 Issue 4, August 2019 UCLA Professor, Dino Di Carlo, discusses his review paper, "Technologies for the Directed Evolution of Cell Therapies." The next generation of therapies is moving beyond the use of small molecules and proteins to using whole cells. Compared with the interactions of small-molecule drugs with biomolecules, which can largely be understood through chemistry, cell therapies act in a chemical and physical world and can actively adapt to that world, amplifying ...
SLAS Technology 24.1 February 2019 Guest Editor Richard M. Eglen of Corning Life Sciences (Tewksbury, MA, USA) talks about a new collection of reviews and original research reports that illustrate how the combination of human iPS cells and 3D cell culture technology provide powerful new approaches to the development of novel and more effective therapies. Free access to the published collection is sponsored by Corning Life Sciences.
SLAS Technology 23.6 December 2018 University of Kansas researchers Yangjie Wei and Nicholas Larson talk about how they used a steady-state/lifetime fluorescence-based, high-throughput platform to develop a general workflow for direct formulation optimization under analytically challenging but commercially relevant conditions.
SLAS Technology 23.5 October 2018 Guest Editor James M. Gill, II, Ph.D., of BFL Consulting (Madison, CT) talks about how the October 2018 issue of SLAS Technology showcases life sciences researchers who are pioneering the use of powerful yet accessible and low-cost IoT technologies in their laboratories. Ten articles illustrate how IoT is being used to optimize factors such as throughput, cost, uptime and result quality.
SLAS Technology 23.4 August 2018 UCLA’s Coleman Murray, Ph.D., talks about his contribution to the August 2018 special issue of SLAS Technology on Enabling Technology in Cell-Based Therapies by guest editor Chris Puleo and his associates at General Electric Global Research. Murray’s article illustrates an important example of how new technologies are changing automation and processing in cell therapy manufacturing.
Volume 23 Issue 3, June 2018 Guest Editor Anand D. Jeyasekharan, Ph.D., of the Cancer Science Institute of Singapore, National University of Singapore, Centre for Translational Medicine, talks about the SLAS Technology special issue on Quantitative Imaging in Life Sciences and Biomedical Research. His insight and the articles in this special issue offer a meaningful glimpse into the potential and applicability of quantitative imaging as life sciences and biomedical research move into an era ...
Volume 23 Issue 2, April 2018 Christian Pylatiuk, Prof. Dr. med., of the Karlsruhe Institute of Technology, Institute for Automation and Applied Informatics in Eggenstein-Leopoldshafen, Germany, discusses his new article, which describes a zebrafish embryo sortying system with two cameras and image processing based on template-matching algorithms.
Volume 23 Issue 1, February 2018 Meet Elodie Sollier-Christen of Vortex Bioscienes as she talks with SLAS Technology Podcast Editor David Pechter about the groundbreaking technology that earned her the 2017 SLAS Innovation Award.
SLAS Technology 22.6 December 2017 Listen to author Weian Zhao of the University of California, Irvine, as he talks about his new article, which summarizes and analyzes representative emerging micro- and nanotechnologies and automated systems for bacterial ID/AST, including phenotypic and molecular methods; discusses representative point-of-care systems that integrate sample processing, fluid handling, and detection for rapid bacterial ID/AST; and highlights major challenges and potential fu...
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