The Gastro Girl Podcast

Auto-brewery syndrome (ABS), sometimes called gut fermentation syndrome, is one of the most misunderstood conditions in digestive health. Patients can experience real symptoms of alcohol intoxication—even when they haven't consumed alcohol—often leading to years of misdiagnosis, stigma, and confusion. In this episode, we explore groundbreaking research published in Nature Microbiology examining how specific gut microbes may produce ethanol inside the body and contribute to auto-brewery syndrome. Host Jacqueline Gaulin, founder of Gastro Girl, is joined by researcher and co-author Barbara Cordell to break down: • What auto-brewery syndrome is and how it affects patients • Why this condition has historically been difficult to diagnose • What new microbiome research reveals about microbial ethanol production • How this science may help validate patient experiences • What clinicians and patients should know moving forward This evidence-based, patient-focused conversation sheds light on a condition that has long been misunderstood—and offers hope for clearer recognition, research, and support.  

Chronic heartburn and GERD are often brushed off as everyday issues—but for some patients, long-term reflux can quietly progress to Barrett's esophagus, the only known precursor to esophageal cancer. In Part 1 of this 4-part U.S.-focused patient education series, foregut surgeon Dr. Dan Lister, Founder of the Arkansas Heartburn Treatment Center, explains how reflux disease can evolve over time and why early recognition matters. In this episode, you'll learn: How chronic GERD can progress silently Why Barrett's esophagus matters—even when symptoms improve or disappear Key warning signs patients should never ignore How Barrett's is detected and risk is assessed in the U.S. Treatment approaches that may help reduce cancer risk Whether you've lived with reflux for years or are newly diagnosed, this episode provides clear, evidence-based guidance to help you take reflux seriously—and take action. This episode is part of a 4-part patient education series sponsored by Castle Biosciences and produced in collaboration with leading U.S. clinicians dedicated to improving outcomes for patients with Barrett's esophagus.  

MASH—metabolic dysfunction–associated steatohepatitis (formerly known as NASH)—is a progressive form of fatty liver disease that often develops silently, without obvious symptoms. Many people don't realize their liver is being damaged until the disease has already advanced. In this episode of the Gastro Girl Podcast, host Jacqueline Gaulin is joined by Dr. Pooja Singhal, a board-certified gastroenterologist, hepatologist, obesity medicine specialist, and founder of the Oklahoma Gastro Health and Wellness Center. Dr. Singhal explains: The difference between MASLD and MASH Why MASH is frequently missed or diagnosed late Why testing—not symptoms—is the only reliable way to assess liver health Who is at risk for developing MASH How MASH is diagnosed and what liver testing involves Why fibrosis (liver scarring) matters Current treatment, prevention, and long-term management strategies How early identification can help reduce the risk of cirrhosis and liver cancer This episode focuses specifically on MASH, the progressive form of fatty liver disease. MASLD is discussed only to help listeners understand how MASH develops and why timely testing matters. Designed to reduce confusion, raise awareness, and empower patients, this conversation equips listeners with the knowledge they need to have informed discussions with their healthcare providers. Thank you to Madrigal Pharmaceuticals for supporting this episode.

Colonoscopy is one of the most effective tools for preventing colorectal cancer—but it's not the only screening option. So how do you know when to get screened, which test to choose, and what to do next if results come back abnormal? Colorectal cancer is one of the most preventable cancers, yet many people delay screening due to confusion or uncertainty. In this Gastro Girl Podcast episode, developed in collaboration with the American College of Gastroenterology (ACG) Patient Care Committee, we're joined by leading gastroenterologist Dr. Aasma Shaukat (NYU Langone Health) and member of the U.S. Multi-Society Task Force on Colorectal Cancer. Dr. Shaukat breaks down colorectal cancer screening in a clear, practical way so you can make informed decisions and take the right next steps with confidence.   What you'll learn: When to start colorectal cancer screening—and who should start earlier Why colorectal cancer is rising in younger adults How family history affects your screening plan Colonoscopy vs stool-based tests—what's the difference What abnormal or incomplete results actually mean Why follow-up testing is critical to prevention How to advocate for the care you nee Why this matters: Early detection saves lives. Completing colorectal cancer screening—including follow-up after abnormal results—can prevent cancer before it starts. This episode is for educational purposes only and is not a substitute for medical advice. Always consult your healthcare provider about your individual care. Explore more trusted digestive health resources: Visit GastroGirl.com or download the Ask Gastro Girl app for evidence-based digestive health guidance you can trust.  

For years, Samantha adapted quietly. She chewed longer, sipped water with every bite, avoided certain foods, and assumed the discomfort was just reflux. It wasn't. In this patient voice episode, Samantha shares the moment she realized something more serious was happening — and how that journey led to a diagnosis of eosinophilic esophagitis (EoE). She opens up about the subtle symptoms many people overlook, the daily adjustments she made without realizing it, and what finally pushed her to seek answers. If swallowing sometimes feels harder than it should, this story may sound familiar. This podcast is for educational purposes only and is not a substitute for medical advice. Always consult your healthcare provider regarding your symptoms or condition. This educational initiative was developed with support from Takeda.  

Bloating is one of the most common digestive complaints but also one of the most misunderstood. Many people experience frequent bloating without knowing what's causing it, whether it's normal, or when it may signal something more serious. In this episode of the Gastro Girl Podcast, host Jacqueline Gaulin talks with gastroenterologist David J. Cangemi from the Mayo Clinic to unpack the real reasons behind bloating and what your digestive system may be trying to tell you. Together, they discuss: • The difference between occasional bloating and chronic bloating • Common causes including diet, IBS, and gut-brain disorders • How constipation and motility issues contribute to bloating • When bloating may be linked to conditions like IBS, food intolerances, or SIBO • Warning signs that should prompt medical evaluation • Practical, evidence-based strategies to safely reduce bloating If bloating is affecting your daily comfort or quality of life, this episode offers trusted, physician-guided insights to help you better understand your symptoms and know when to seek care. This episode is produced in collaboration with the American College of Gastroenterology Patient Care Committee.

Fecal incontinence (FI) affects nearly 8% of adults worldwide, yet many people suffer in silence due to embarrassment, confusion, or the belief that nothing can be done. This episode is here to change that. We're joined by Dr. John William Blackett, gastroenterologist and lead author of "Fecal Incontinence in Adults: New Therapies," published in The American Journal of Gastroenterology. Dr. Blackett offers a compassionate, patient-centered overview of FI, including common causes, diagnostic testing, and the full range of treatment options available today—highlighting newer and emerging therapies. If you've experienced unexpected leakage, urgency, staining, or difficulty controlling bowel movements—or if you support someone who has—this conversation provides clarity, reassurance, and practical guidance. Effective treatments exist, and help is available. This episode is produced in collaboration with the American College of Gastroenterology Patient Care Committee.

Living with IBS-C isn't just about managing physical symptoms, it's also about navigating the fear, worry, and emotional toll that often come with the condition. In this powerful episode, host Jacqueline Gaulin is joined by Dr. Sarah Ballou, clinical psychologist and Director of the GI Psychology Service at Beth Israel Deaconess Medical Center, to explore how fear shows up along the IBS-C journey and what you can do to face it with confidence and support.   In this episode, you'll learn: The most common fears IBS-C patients experience and how they influence daily life and treatment decisions Why fear can sometimes hold you back from finding relief Practical tools to help you feel more in control, confident, and hopeful How to talk openly with your provider about the fears that affect your care Whether you're newly diagnosed or feeling stuck after years of symptoms, this episode offers real-world guidance, emotional validation, and a reminder that you're not alone on this journey.   This episode is sponsored by Ardelyx.  

In this follow-up to one of our most popular episodes, host Jacqueline Gaulin welcomes back Dr. Mark Pimentel, Executive Director of the Medically Associated Science and Technology (MAST) Program at Cedars-Sinai, to dive deeper into the science behind SIBO (Small Intestinal Bacterial Overgrowth) and IMO (Intestinal Methanogen Overgrowth). Dr. Pimentel answers listener questions and explains how these complex conditions relate to IBS-D and IBS-M, why methane and archaea matter for gut health, and how motility and the Migrating Motor Complex (MMC) play a crucial role in prevention and treatment. You'll also learn about the latest insights and therapeutic approaches that can help patients find lasting relief. Produced in collaboration with the American College of Gastroenterology's Patient Care Committee, this evidence-based discussion helps you better understand the "why" behind SIBO and IMO—and what steps you can take toward better gut health.

In this inspiring episode of the Gastro Girl Podcast, host Jacqueline Gaulin sits down with Mel, an award-winning dog enthusiast from Valrico, Florida, who has earned more than 40 American Kennel Club titles with her beloved Schnauzers. After life-changing surgery that left her with a permanent colostomy, Mel refused to let fear or stigma hold her back. She shares how she reclaimed her confidence, advocated for her own healthcare, and found strength through her passion for dogs. This episode offers hope and insight for anyone learning to live fully after surgery—and a reminder that resilience, love, and purpose can shine through even the toughest challenges.

Starting a new IBS-C treatment can bring a mix of hope and uncertainty. How soon will it work? What if side effects appear? Should you keep going or call your doctor? Host Jacqueline Gaulin sits down with Dr. Brian Lacy, gastroenterologist at Mayo Clinic in Jacksonville, FL, to answer the real questions patients ask when starting treatment. In this episode, we discuss: • What patients can realistically expect in the first days and weeks of treatment • What "feeling better" truly means for each individual • Common challenges and side effects patients may experience • How to stay encouraged and avoid stopping treatment too soon without consulting your doctor Relief takes time—and you're not alone on this journey. This episode is made possible with support from Ardelyx.

Hemorrhoids are one of the most common—and misunderstood—digestive conditions, yet many patients still suffer in silence. In this candid, patient-focused episode, host Jacqueline Gaulin talks with Mitch Guttenplan, MD, FACS, a general surgeon and Medical Director for the CRH O'Regan System, to break the stigma and share clear, evidence-based guidance about hemorrhoids. Dr. Guttenplan explains the difference between internal and external hemorrhoids, how to recognize common symptoms, and which lifestyle changes can help reduce discomfort and prevent recurrence. He also walks through current treatment options—including the CRH O'Regan System—so patients can better understand what's available and when it's time to seek medical care. This episode is sponsored by the CRH O'Regan System.

Gravity keeps us grounded—but it also shapes our bodies, minds, and even our gut health in surprising ways. In this fascinating episode, Dr. Brennan Spiegel, Director of Health Services Research at Cedars-Sinai and author of PULL: The Science of Gravity and How It Shapes Our Health and Happiness, joins Jacqueline Gaulin, host of the Gastro Girl Podcast, to explore how gravity influences digestion, mood, metabolism, and mental resilience. Discover what "gravity resilience" means, why astronauts help us understand life on Earth, and how this invisible force could hold the key to living longer, standing stronger, and finding balance in body and mind. You'll learn: • How gravity affects digestion, circulation, and well-being • The surprising link between gravity, depression, and emotional health • Ways to strengthen your "gravity resilience" through movement, nutrition, and mindfulness Listen to more expert insights at GastroGirl.com. Pull is available by visiting Dr. Spiegel's website or wherever books are sold.  

When a child has trouble eating, gaining weight, or explaining discomfort while swallowing, it can be heartbreaking for parents and confusing for the child. These may be early signs of Eosinophilic Esophagitis (EoE) — a chronic inflammatory condition of the esophagus that affects how food moves through the digestive tract. In this episode, pediatric gastroenterologist Dr. Joshua B. Wechsler from Northwestern Medicine shares what families need to know about recognizing EoE early, getting an accurate diagnosis, and navigating treatment options. He also offers guidance on helping children manage EoE at school, during meals, and in social settings — so they can live healthier, happier lives. See related episode   Growing Up with EoE: A Family's Journey from Childhood to College Resources & Support: Find trusted, evidence-based information and resources on EoE at gastrogirl.com. This episode is sponsored by Sanofi and Regeneron.  

What happens when physicians and advanced practice providers (APPs) truly work as a team in managing inflammatory bowel disease (IBD)? In this episode, we're joined by Dr. Jennifer Seminerio, Director of Inflammatory Bowel Disease and Associate Professor of Medicine, and Megan Pearce, DNP, APRN, FNP-C, from the AdventHealth IBD Clinic in Orlando, FL. Together, they share how collaborative APP/MD relationships enhance patient trust, streamline care, and support shared decision-making for those living with Crohn's disease and ulcerative colitis. We'll explore: How APP/MD teamwork improves patient experiences Practical tips to get the most out of clinic visits Ways to navigate complex treatment decisions together Dr. Seminerio and Megan also highlight the inaugural AdventHealth Crohn's and Colitis Patient Education Conference, presented by the AdventHealth IBD Program, happening Saturday, October 11, 2025, at the Renaissance Orlando at SeaWorld®. This event will bring together patients, caregivers, and experts to share education, support, and community for all impacted by IBD.

What's it really like for a child to live with eosinophilic esophagitis (EoE)? In this inspiring episode, we sit down with Jeni and her son Joshua, who share their family's journey navigating the challenges of pediatric EoE. From the earliest warning signs to Joshua preparing for life at college, their story sheds light on the resilience it takes to manage this condition day-to-day. Together, we explore: Why getting the right diagnosis can take time The pros and cons of today's treatment options How parents can interpret symptoms when children struggle to describe them Tips for transitioning from pediatric to adult care Whether you're a parent, patient, or healthcare provider, you'll walk away with insights, encouragement, and practical takeaways. Resources & Support: Find trusted information and resources on EoE at gastrogirl.com. This episode is sponsored by Sanofi and Regeneron.  

What does preventive care really mean for people living with inflammatory bowel disease (IBD)? In this episode, we break down the latest ACG Clinical Guideline Update: Preventive Care in IBD with two of its lead authors, Dr. Francis Farraye (Mayo Clinic, Jacksonville, FL) and Dr. Freddy Caldera (University of Wisconsin School of Medicine and Public Health). Together, we explore: Why preventive care is critical in IBD management Key vaccination recommendations for IBD patients How to prioritize cancer and bone health screening The role of mental health and lifestyle in long-term outcomes Produced in collaboration with the American College of Gastroenterology's Patient Care Committee, this episode offers clear, evidence-based insights for both patients and providers.  

Living with IBS-C often requires more than just medications. In this episode, host Jacqueline Gaulin is joined by Dr. Kumkum Patel, a board-certified gastroenterologist in Newport Beach, CA, who specializes in treating IBS patients (find her at kumkumpatelmd.com or @dr.gut_motility). Together, they explore how to integrate complementary therapies into your care plan to help you feel and function better. You'll learn: How nutrition can support IBS-C management—and where to start Why stress can make symptoms worse What emerging research says about the gut microbiome and probiotics How to figure out which therapies are right for you Why shared-decision making with your healthcare provider is key This episode is made possible with support from Ardelyx.  

Diverticulosis and diverticulitis sound alike but are very different conditions—and knowing the difference is key to protecting your digestive health. In this episode, host Jacqueline Gaulin welcomes Dr. Lisa Strate, Professor and Chief of Gastroenterology and Hepatology at the University of Wisconsin, and one of the nation's leading experts in diverticular disease. Together, they clear up common questions and misconceptions about diverticulosis and diverticulitis, including: What causes these conditions and who is most at risk The symptoms and warning signs patients should watch for Whether it's possible to have one without the other How diet and lifestyle affect treatment and prevention This episode is produced in collaboration with the American College of Gastroenterology's Patient Care Committee.  

In this episode, we share Wendy's story of living with Eosinophilic Esophagitis (EoE). She takes us through the confusing early symptoms, the long road to getting a diagnosis, and how she manages her condition today. With honesty and hope, Wendy offers a patient's perspective on what it means to live with EoE. Hear Wendy discuss: The first signs that something was wrong with her throat How symptoms disrupted her eating, social life, and mental health The coping strategies she unknowingly developed along the way What it was like to finally receive an accurate diagnosis and treatment plan Resources & Support:Learn more about EoE and find trusted resources at gastrogirl.com. This episode was made possible with support from Sanofi and Regeneron.