Biohacking Beauty: The Anti-Aging Skincare Podcast

In this episode of the Biohacking Beauty podcast, Dr. Amie Hornaman discusses the core function of thyroid and why it is considered as the master gland. She also shares her misdiagnosis experiences and how it affected her treatment. She talks about the importance of talking to a specialist and understanding the overall treatment approach in optimizing the effects of it to the body. Dr. Amie Hornaman, also know as The Thyroid Fixer, the founder of the Institute for Thyroid and Hormone Optimization. She is on a mission to optimize thyroid patients around the world and give them their lives back using her proprietary transformational program: The FIX Method. She is also. She experienced misdiagnoses and improper treatment so she is set to help others out and avoid the same pitfalls that she had to get a correct diagnosis. 5:15 - Thyroid as the body’s master gland 7:53 - How important is our thyroid?12:00 - Why thyroid functions sub optimally?15:45 - Are thyroid issues hard to diagnose correctly? 24:53 - How to optimize the body’s framework to match their treatment?33:24 - What are Dr. Amie’s survival stress recommendations?42:00 - How do we manage Hormetic Stressors?44:54 - Is metformin part of Dr. Amie’s treatment plan for losing weight? 47:10 - Dr. Amie’s general approach in creating new products52:47 - Benefits of taking T254:00 - What should we prioritize when talking about overall body health?57:15 - Is Dr. Amie available for remote consultation?Find more from Young Goose:Website: https://www.younggoose.com/Instagram: @young_goose_skincare What to know more about Dr. Amie?Websites: https://dramiehornaman.com/ | https://thethyroidfixer.com/Linkedin: Dr. Amie HornamanFacebook: Dr. Amie HornamanYouTube: Dr. Amie HornamanGet 20% off your first purchase by using code PODCAST20 at www.younggoose.com

Most people know NAD+ as a supplement trend. But very few understand what's actually happening inside their skin cells when it runs out or what's stealing it in the first place.By the time you're 45, you've lost half of the molecule that powers virtually every function keeping your skin young. Sadly, it only gets worse from there. The enzyme your skin uses for DNA repair can wipe out up to 90% of what's left after a single afternoon in the sun. This isn't a slow, graceful decline. It's a collapse happening beneath the surface long before the wrinkles appear.In this episode, we will nerd out and break down exactly why NAD+ disappears, who the thieves are, and what the science actually says about getting it back. From the sirtuin-PARP-CD38 trifecta to the zombie cell feedback loop that accelerates the drain with age, this is the most complete picture of NAD+ and skin aging we've put together to date.We also cover the real differences between NMN, NR, and niacin, why the precursor you choose actually matters, and what to stack with it to protect your methylation pathways.Ready to nerd out in this with us?Let's dive in!What's Discussed:(4:00) The number that changes how you think about skin aging.(6:03) What NAD+ actually does and why "rechargeable battery" undersells it.(8:18) The three enzyme families consuming your NAD+ as a substrate.(8:23) Sirtuins: the police of your cells and what they cost you.(9:42) PARPs: the fire brigade and why one sunburn nearly wipes you out.(11:16) CD38: the NAD+ Pac-Man that gets worse with age.(15:10) The five-fold decline: what the 2012 tissue study actually found.(16:15) CD38 and the zombie cell feedback loop driving the decline.(19:39) What the depletion actually looks like in the mirror.(28:04) Why NAD+ decline is reversible & supplementation deep dive.(28:41) NMN: how it works and what the studies actually show.(31:50) NR: the most clinically studied precursor and who it's best for.(33:27) Niacin: the $5 option and why most people can't tolerate it.(38:14) Why timing your NAD+ to your circadian rhythm matters.(38:35) TMG and methylation: what to stack and the two-to-one ratio.Learn more about NAD from our previous podcasts and videos:Previous NAD YouTube Videos:NAD+, Skincare Science + The Future of Skincare: https://www.youtube.com/watch?v=ZmwYLywwcsA Biohack Your Way to Better Skin - Benefits of NAD Boosting Supplementation for Skincare & Anti-Aging: https://www.youtube.com/watch?v=KIz5MvW7X1M Why Your NAD+ Supplement Isn't Helping Your Skin | The Truth: https://www.youtube.com/watch?v=euIj0eLt4Aw The Science Behind NAD+, Link Between NAD+ Skin Aging, Importance of Precursors: https://www.youtube.com/watch?v=wmsUeQklYY0 The NAD+ Protocol That Could Reverse Skin Aging (Doctors Won't Tell You) | Dr. Scott Sherr: https://www.youtube.com/watch?v=iYJgVSoj_XM Previous NAD Podcasts:NAD 101: Unlocking The Secrets To Youthful Skin: https://podcasts.apple.com/us/podcast/nad-101-unlocking-the-secrets-to-youthful-skin/id1552026927?i=1000652231123 The Relationship Between NAD+ and Your Skin, NAD+ Depletion, Bioavailability, Precursors, Sirtuins, and More: https://podcasts.apple.com/us/podcast/22-the-relationship-between-nad-and-your-skin/id1552026927?i=1000568088462 The Science Behind NAD+, the Link Between NAD+ and Skin Aging, and the Importance of Precursors: https://podcasts.apple.com/us/podcast/the-science-behind-nad-the-link-between-nad-and/id1552026927?i=1000615122098 Ben Azadi: How NAD+ Helps Reverse Aging + Skin Problems Connected to Deeper Health Issues: https://podcasts.apple.com/us/podcast/ben-azadi-how-nad-helps-reverse-aging-skin-problems/id1552026927?i=1000662495945 Turn Back the Clock: NAD and Skin Biohacking: https://podcasts.apple.com/us/podcast/turn-back-the-clock-nad-and-skin-biohacking/id1552026927?i=1000681105344 Research Studies Mentioned: Age-Associated Changes In Oxidative Stress and NAD+ Metabolism In Human Tissue: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0042357 CD38 Dictates Age-Related NAD Decline and Mitochondrial Dysfunction: https://www.cell.com/cell-metabolism/fulltext/S1550-4131(16)30225-7 Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages: https://www.nature.com/articles/s42255-020-00305-3 Enhanced SIRT1 Activity Mitigates UVB-Induced Senescence in Dermal Fibroblasts: https://pubmed.ncbi.nlm.nih.gov/39401943/ Slc12a8 is a nicotinamide mononucleotide transporter: https://www.nature.com/articles/s42255-018-0009-4 The efficacy and safety of β-nicotinamide mononucleotide (NMN) supplementation in healthy middle-aged adults: https://link.springer.com/article/10.1007/s11357-022-00705-1 Nicotinamide riboside and nicotinamide mononucleotide facilitate NAD+ synthesis via enterohepatic circulation: https://www.science.org/doi/10.1126/sciadv.adl5154 Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults: https://www.nature.com/articles/s41467-018-03421-7 Find more from Young Goose:Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://younggoose.comInstagram: @young_goose_skincareHead to younggoose.com/products/youth-body-cream for 20% offBody Cream: Head to younggoose.com/products/youth-body-cream for 20% off

Most people treat their skin like a surface problem. But almost every persistent skin issue, from rosacea to eczema to accelerated aging, has something deeper driving it.That deeper driver is almost always the gut, the liver, or a backed-up detox pathway. We at Young Goose, always believe that skincare is whole body care and we want our community to identify the deeper causes of skin issues that products alone can’t fix.In this episode, functional nutrition practitioner Dani Conway joins us to break down why the skin is not the origin of the problem but the exit sign. When the body cannot eliminate toxins efficiently, they take the path of least resistance. For a lot of women, that path is the skin on their faces.Dani brings nearly 20 years of clinical practice to this conversation, along with a sharp, evidence-grounded perspective on why fixing hormones first is often the wrong starting point and what to address instead.We go deeper into this in the latest episode of Biohacking Beauty: The Anti-Aging Skincare Podcast. We also cover how to deal with food sensitivities, common misconceptions around hormones and blood sugar testing, and the use of GLP-1 and peptide use. Let’s dive in!What's Discussed:(0:57) How poor detoxification shows up on the skin.(2:09) The foundational actions to support detox.(5:44) The lymphatic system explained.(6:33) Why Dani stopped addressing hormones first.(8:01) Microplastics, endocrine disruptors, and chemicals women apply to their skin. (11:40) The gut-skin axis: How gut symptoms always end up on your face.(13:55) NAD, CD38, and why a bacterial infection in your gut affects cell energy. (16:59) Why peptides and NAD supplements don't work if the foundation isn't dialed in first.(21:26) Can you actually fix hormones or just manage them?(25:12) Real-world food sensitivity examples and how to figure out your personal triggers. (29:41) How to run an elimination diet correctly.(34:39) The big picture nobody talks about: it's not the food, it's the immune system.(36:06) The new science on acne: The bacteria and immune system response.(38:06) Hot take: Why immune optimization is the next mitochondria.(39:49) CGMs and skin aging: Why Dani actually pulls clients back from data obsession. (42:09) Fasting insulin ranges: Why the lab's "normal" range is dangerously wide.(43:35) The role of GLP-1s and how to use them as a therapy instead of a crutch. (45:12) Dani's hot take on berberine and leptin resistance.Find more from Young Goose:Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://younggoose.comInstagram: @young_goose_skincareFind more from Dani Conway:Instagram: @DaniConwayOfficialWebsite: https://nutritionthenaturalway.com/The Wellness Collective: https://nutritionthenaturalway.com/drop-the-weight-shred-the-fat/Weight Loss Accelerator Program: https://go.nutritionthenaturalway.com/wlaFree Complimentary Guide: https://go.nutritionthenaturalway.com/hhh

Most people think that the stinging feeling, redness or tightness are always good signs of skin detoxification. Tricky enough, it can look like ‘glass skin’ or skin renewal. However, almost always the temporary tight and bright skin is a skin barrier issue in disguise.Skin barrier damage is one of the most misread signals in skincare. It looks like purging but it is actually your skin telling you it has been pushed past its limit.It’s easy to think there’s no damage at all because overexfoliation can temporarily give a satisfying baby skin at the cost of long-term skin wellness.One of the best ways to distinguish normal skin stimulation versus barrier damage is to understand your skin biology. As Anastasia always says, "We're not chasing a 10-day glow. We're chasing a 10-year outcome." We go deeper into this in the latest episode of Biohacking Beauty: The Anti-Aging Skincare Podcast. We also cover what real skin barrier repair should feel like, the pillars of skin wellness, and how to listen better to your skin to train it to become more resilient.Resources mentioned:Barrier Protocol: https://www.younggoose.com/pages/barrier-protocolWhat's Discussed:(04:20-05:11) Why a weak skin barrier makes every other skincare step stop working(05:11-06:16) The four signs of barrier damage that looks like progress(06:16-08:29) What is a skin barrier and what happens when the lipid ratio breaks down(08:29-10:10) How barrier disruption can disguise as purging(10:10-13:00) A case study of laser-induced barrier damage and the cycle of over-treatment(13:00-15:11) The three pillars of skin wellness: performance, resilience, and longevity(15:11-16:52) What your skin should be able to do before you add any heavy stimulation(16:52-18:30) The three-step barrier reset protocol(18:30-20:30) Morning versus nighttime barrier: defense vs. repair(20:30-25:09) The truth about exfoliation culture and the glass skin trend(25:09-27:00) How to build an exfoliation schedule that works for your skin typeFind more from Young Goose:VAMPIRE EXOSOMES → Professional Exosome Serum for Regeneration and Post-Treatment RecoveryUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://younggoose.comInstagram: @young_goose_skincare

Did you know that the most powerful anti-aging protocol isn't about how long you sleep? It's about when. Getting eight hours of sleep for skincare feels like a tough feat to achieve especially when life gets in the way.By understanding how your skin begins its optimal repair time, it’s still possible to achieve the best skin results without the guilt of not sleeping enough.In our quest in finding the best skincare ingredient for our products, we discovered that hours of sleep do matter, but best skin results happen by following the skin’s optimal program sequences for deep repair.We go deeper into this in the latest episode of Biohacking Beauty: The Anti-Aging Skincare Podcast. We also cover how melatonin onset, circadian rhythm, growth hormones, and inflammation play a huge role in giving your skin the environment it needs to do its best work.What's Discussed:(1:54-5:09) Why sleep timing matters more than sleep hours for skin repair(07:01-15:19) The three repair windows your skin depends on every night: melatonin onset, growth hormone pulse, and barrier recovery(05:09-5:55) Why dull skin, slow healing, and crepey eyes are often a timing problem — not a product problem(13:28-17:10) How to build a recovery-first nighttime routine before adding any stimulation(37:47-40:47) The silk vs. cotton pillowcase: Which fabric choice is part of your skincare(43:29-47:36) Supplements that support skin repair at night(17:17-17:30) Red light therapy as the only exception to the no-stacking ruleResources mentioned:Sleep protocol: https://www.younggoose.com/pages/sleep-protocolEpisode with Anastasia (BeautyFascia): https://podcasts.apple.com/us/podcast/anastasia-beauty-fascia-facial-fascia-and-massageEpisode on Face Taping with Olga from Natural Face Bible: https://podcasts.apple.com/us/podcast/real-japanese-face-taping-explained-with-olgaFind more from Young Goose:The Elastin Action Protocol → Engineered for Skin Navigating Elasticity ChangeThe Winter Skin Protocol → Build for How Skin Actually Behaves in WinterVAMPIRE EXOSOMES → Professional Exosome Serum for Regeneration and Post-Treatment RecoveryUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://younggoose.comInstagram: @young_goose_skincare

Molecular hydrogen is often described as a selective antioxidant, but that framing is incomplete. In this episode, we explore hydrogen as a mitochondrial hormetic signal that can influence redox balance, inflammatory regulation, and adaptive stress pathways. The key distinction is that delivery route changes mechanism. Oral, inhaled, and topical hydrogen act differently in the body, with different kinetics, tissue distribution, and biological implications.We dive deeper into this in the Biohacking Beauty Podcast with Alex Tarnava. We discuss why topical hydrogen is gaining attention for skin outcomes, how gut-mediated signaling may drive systemic effects, and why interpreting evidence requires understanding study design, delivery method, and real-world product variability.WHAT’S DISCUSSED:(04:52) Why hydrogen is not a traditional antioxidant and what that actually means biologically(06:17) How different delivery routes change tissue targeting and systemic signaling(10:09) Why skin aging and inflammatory conditions behave more like a systems problem than a single pathway(15:10) How mild oxidative stress can activate endogenous antioxidant production(16:05) The hidden risk of reductive stress from excessive antioxidant use(17:59) Why inflammation must be regulated rather than suppressed for long-term tissue repair(28:52) The gut-driven mechanisms that may influence visible skin outcomes(29:42) How corporate-owned research and investigator-led studies shape the hydrogen evidence landscape(37:25) Why exaggerated longevity claims distort innovation and erode trust(50:49) The growing issue of counterfeit hydrogen products and what it signals about market maturityFind more from Young Goose:The Elastin Action Protocol → Engineered for Skin Navigating Elasticity Change Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://younggoose.comInstagram: @young_goose_skincareFind more from Alex Tarnava:Website: https://hydrogenwatertablets.com https://alextarnava.comInstagram: https://www.instagram.com/alextarnava

Chronic stress isn’t just a mental or emotional burden. It creates a biological cascade that disrupts mitochondrial function, accelerates inflammation, and shows up visibly in the skin long before deeper symptoms appear.We dive deeper into this in the Biohacking Beauty Podcast with Dr. Scott Sherr. We also talk about the sympathetic spiral of doom, why skin reflects mitochondrial decline before other symptoms appear, and why sequencing interventions matter more than intensity.Dr. Scott Sherr is a board-certified internal medicine physician certified in Health Optimization Medicine (HOMe) and a specialist in Hyperbaric Oxygen Therapy. He is the COO of Troscriptions and focuses clinically on mitochondrial health, stress physiology, and advanced recovery protocols.What's Discussed:(01:52) Why chronic stress is not just mental and directly impacts cellular energy(05:17) How modern life keeps the nervous system stuck in chronic fight or flight(07:25) Cortisol and stress hormones disrupting mitochondria and accelerating skin aging(11:16) Why skin aging is often the first visible sign of mitochondrial decline(24:16) The sympathetic spiral of doom explained through energy loss and stress signaling(27:14) Why stress reduction and mitochondrial support must happen at the same time(46:22) Why aggressive skincare and biohacking fail without mitochondrial resilience(50:35) Hyperbaric oxygen therapy, sequencing, and why timing matters more than intensityFind more from Young Goose:The Elastin Action Protocol → Engineered for Skin Navigating Elasticity Change The Winter Skin Protocol → Build for How Skin Actually Behaves in Winter VAMPIRE EXOSOMES → Professional Exosome Serum for Regeneration and Post-Treatment RecoveryUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://younggoose.comInstagram: @young_goose_skincareFind more from Dr. Scott Sherr:Website: https://troscriptions.comLinkedIn: @troscriptionsInstagram: @drscottsherr @troscriptionsFacebook: @TroscriptionsYoutube: @troscriptionsTiktok: @troscriptions

Fascia is one of the most overlooked conversations in skin aging. We spend so much time thinking about collagen, serums, injectables, and trending tools, but very few people are talking about the structural system underneath the skin that influences how we actually age.If you are dealing with under-eye puffiness, jaw tension, posture changes, facial asymmetry, or feeling like your face looks more tired than it should, this episode explores a deeper layer of the conversation. We dive into fascia, fluid movement, breathing patterns, and why your neck and jaw may be playing a much bigger role in your appearance than you realize.In this conversation, we break down what fascia really is in simple terms and how it connects to collagen production, lymphatic drainage, nervous system regulation, and facial structure over time.Anastasia is a board-certified Structural Integration Therapist trained in kinesiology, facial muscle neuro rehabilitation, neurovascular release, myofascial release, traditional Chinese medicine, and acupressure. Over the past five years, she has pursued global mentorships and seminars focused on structural and facial regeneration, bringing together multiple disciplines to support facial health, tissue quality, and overall structural balance.To watch this episode on Youtube click here: https://youtu.be/KRs4dlmfj8sWhat's Discussed:(11:41) Why facial massage does not stretch skin and how tissue actually adapts(19:38) Under eye puffiness as a drainage issue, not a skin problem(23:12) Collagen cross linking and why fibroblasts avoid rebuilding on damaged matrix(27:23) Glymphatic dysfunction and how poor brain drainage shows up in the face(51:52) What happens to circulation and lymphatic flow when muscles are paralyzed with Botox(53:52) Why mewing fails without addressing neck tension and structural foundation(01:12:23) Phone posture, forward head position, and structural facial aging(01:14:39) Aging as a structural shift before wrinkles ever appearFind more from Young Goose:The Elastin Action Protocol → Engineered for Skin Navigating Elasticity ChangeThe Winter Skin Protocol → Build for How Skin Actually Behaves in WinterVAMPIRE EXOSOMES → Professional Exosome Serum for Regeneration and Post-Treatment RecoveryUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://younggoose.comInstagram: @young_goose_skincareFind more from Anastasia (Beauty Fascia):Website: https://anastasia.beautyInstagram: @anastasiabeautyfasciaYoutube: @anastasiabeautyfasciaTikTok: @anastasiabeautyfascia

Being told your labs are “normal” and your cycle is still regular does not mean your metabolism and hormones are stable. Early insulin resistance can quietly increase inflammation, drive midsection fat gain, and accelerate skin aging years before menopause is officially diagnosed.In this Biohacking Beauty episode with Dr. Jila Senemar, we break down why regular periods do not rule out perimenopause, why building muscle is one of the most powerful metabolic tools in midlife, and how early testing like DEXA scans can reveal hidden bone loss long before standard guidelines would ever check.Dr. Jila Senemar is a board-certified OB/GYN with more than 20 years of clinical experience. She is a menopause specialist certified by The Menopause Society and a longevity physician. Her clinical work focuses on perimenopause, menopause, hormone therapy, and midlife women’s health.What's Discussed:(02:57) Insulin resistance as an early midlife driver of inflammation and weight gain(03:35) Why more cardio and restriction can worsen midlife metabolic dysfunction(07:27) Regular periods and no hot flashes still align with early perimenopause(09:44) Night waking and unrefreshing sleep as overlooked perimenopause symptoms(15:01) Strength training as a metabolic and hormonal support tool in midlife(24:40) Using DEXA scans at 40 to detect early bone density loss(26:15) Hormone therapy framed around longevity, not just symptom relief(41:14) Progesterone’s role in sleep, mood stability, and early perimenopause supportFind more from Young Goose:The Elastin Action Protocol →  Engineered for Skin Navigating Elasticity Change The Winter Skin Protocol → Build for How Skin Actually Behaves in Winter VAMPIRE EXOSOMES → Professional Exosome Serum for Regeneration and Post-Treatment RecoveryUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://younggoose.comInstagram: @young_goose_skincareFind more from Dr. Jila Senemar MD, FACOG, MSCP:Website: https://www.jilamd.comInstagram: @drjilasenemar

Advanced skincare routines are more popular than ever, yet dryness, laxity, and visible aging still persist. The issue isn’t effort or discipline. It’s that skin aging is being treated as a surface-level problem instead of a cellular and structural one.We dive deeper into this in the latest Biohacking Beauty Podcast with Jess Kane. We also chat about how cell membrane health shapes visible aging, why omega fats are widely misunderstood, and how most “liposomal” supplements never reach the cell.Jessica Kane is the Co-Owner and Chief Marketing Officer of BodyBio, a third-generation wellness company specializing in cellular health. She works alongside healthcare practitioners and researchers to translate complex cell membrane and lipid science into practical, evidence-based solutions. What's Discussed:(06:17) Why advanced skincare and red light therapy still fail without cellular building blocks(07:37) How low-fat nutrition and missing lipids weaken skin structure over time(09:55) Cell membranes explained as the foundation of skin barrier, tone, and elasticity(10:46) How phospholipids act as the “cement” between skin cells and prevent laxity(13:15) Why the omega-6 to omega-3 ratio matters more than taking fish oil alone(15:57) Why most phosphatidylcholine on the market is not truly liposomal(18:28) How “liposomal” labeling works and why most supplements fail cellular delivery(36:01) Why vitamin C and glutathione don’t impact collagen without proper absorptionFind more from Young Goose:Find our Elastin Protocol here: https://younggoose.com/pages/elastin-action-protocol-landingFind our Winter Protocol here: https://younggoose.com/pages/winter-protocolVAMPIRE EXOSOMES → Professional Exosome Serum for Regeneration and Post-Treatment Recovery: https://younggoose.com/products/vampire-exosomesUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://younggoose.com/?utm_source=podcast&utm_medium=appleInstagram: http://instagram.com/young_goose_skincareFind more from Jess Kane: Website: https://bodybio.com/Instagram: https://instagram.com/jesskaneInstagram: https://www.instagram.com/bodybio/Tiktok: https://tiktok.com/@jesskaneb

It’s Valentine’s Day, and while we don’t usually shape our work around holidays, this one felt different because we’re not just co-founders of Young Goose, we’re life partners. For us, care has always shown up in daily choices and consistency, the same philosophy behind how we think about skin longevity.In this special episode, we flip the format and recommend ingredients to each other based on real-time skin needs. We get into methylene blue, NAD support, ectoin, retinol, and repair-focused actives through the lens of cellular energy, inflammation control, repair, and long-term resilience.If you’re listening on Valentine’s Day, we’re honored you’re spending it with us. And if you’re tuning in any other day, we’re just as glad you’re here. Either way, this conversation is about care that lasts and the small, intentional choices that add up over time.What's Discussed:(03:38) Why this Valentine’s episode feels different as co-founders and life partners(06:11) Recommending ingredients based on real-time skin needs, not bias(12:38) Methylene blue, red light synergy, and mitochondrial skin energy(17:04) NAD support as the currency behind repair and long-term resilience(20:49) Ectoin, deep hydration, and protection from blue light and pollution(25:10) Retinol results, limitations, and why peptide alternatives matter(27:36) Sun exposure, oxidative stress, and the missing piece of post-UV DNA repairFind more from Young Goose:The Elastin Action Protocol →  Engineered for Skin Navigating Elasticity Change The Winter Skin Protocol → Build for How Skin Actually Behaves in Winter VAMPIRE EXOSOMES → Professional Exosome Serum for Regeneration and Post-Treatment RecoveryUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://younggoose.comInstagram: @young_goose_skincare

Skin problems are often the body’s earliest warning sign that detoxification, inflammation control, and nutrient absorption are already compromised. When detox demand rises and recovery systems can’t keep up, skin changes and aging-related signs become more pronounced.In this episode of the Biohacking Beauty Podcast, we sit down with Marina Moiseyeva to explore why medications and aggressive topicals increase detox load, how sweating and lymphatic movement support skin longevity, and why “Ozempic face” is driven by muscle, bone, and nutrient loss rather than fat alone.Marina Moiseyeva is a Functional Medicine Practitioner and Board Certified Family Nurse Practitioner with 16 years of clinical experience. She is a Certified Diplomate in Anti-Aging and Regenerative Medicine, a member of the American Academy of Anti-Aging Medicine, and the author of Harmonious Healing Blueprint: Biohacking, Regeneration & Health Resilience.What's Discussed:(00:00) Why skin functions as a detox organ(07:03) How topical treatments and medications quietly increase the body’s detox burden(11:34) Sweating, hydration, and lymphatic movement as primary detox pathways(19:32) GLP-1s, nutrient absorption, and the real mechanism behind “Ozempic face”(26:09) Bone density, muscle loss, and why structural facial aging is hard to reverse(54:48) What ages skin faster than sun exposure and why sugar-driven inflammation mattersFind more from Young Goose:Find our Elastin Protocol here: https://younggoose.com/pages/elastin-action-protocol-landingFind our Winter Protocol here: https://younggoose.com/pages/winter-protocolVAMPIRE EXOSOMES → Professional Exosome Serum for Regeneration and Post-Treatment Recovery: https://younggoose.com/products/vampire-exosomesUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at younggoose.comInstagram: @young_goose_skincareFind more from Marina Moiseyeva:Website: https://liveharmoniouslife.comInstagram: @liveharmoniouslife Books' Amazon page links here: Hardcover: https://a.co/d/asQyFGW Paperback: https://a.co/d/gRQhEWE

Advanced skin treatments often underperform for a reason rarely addressed: regeneration cannot occur in a chronically stressed or under-resourced system. Elevated cortisol, inflammation, and metabolic imbalance weaken collagen signaling and tissue repair before any device, injectable, or modality has a chance to work.In this episode of the Biohacking Beauty Podcast, we sit down with Joe Radich from R3 Health to unpack why physiological preparation determines treatment outcomes. We explore how internal factors like stress, hormones, micronutrients, and metabolic health shape skin regeneration, and why modalities like peptides, hyperbaric oxygen, and exosomes only work as well as the system they’re introduced into.Joe Radich is an NCCPA board-certified Physician Assistant specializing in regenerative medicine and the founder of R3 Health. He trains physicians and mid-level practitioners in stem cells, PRP, exosomes, and biohacking-based clinical protocols, with expertise spanning orthopedic, aesthetic, hair restoration, and regenerative applications.What's Discussed:(06:42) Why chronic stress and cortisol are silent drivers of visible skin aging(10:18) Preparing the body before skin treatments and why physiology determines outcomes(14:07) Why microneedling success depends on internal biology, not just technique(18:55) The most common lab patterns behind poor skin regeneration and chronic inflammation(24:31) Hormonal imbalance vs hormone deficiency and how both affect skin aging(33:41) GHK-Cu and peptides as signaling tools for connective tissue regeneration(38:09) Hyperbaric oxygen as a force multiplier for skin repair, recovery, and longevity(44:06) Exosomes and regenerative biologics and why sourcing and quality determine resultsFind more from Young Goose:VAMPIRE EXOSOMES → Professional Exosome Serum for Regeneration and Post-Treatment Recovery → Vampire ExosomesUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at www.younggoose.com    Instagram: @young_goose_skincareWinter Skincare Protocol: https://www.younggoose.com/pages/winter-protocol Find more from Joe Radich (R3 Health):Website: https://josephradich.com, https://r3health.coInstagram: @joeradich_

Skin sagging, crepiness, and loss of bounce are often blamed on collagen loss, yet the real driver sits elsewhere in the skin’s architecture. Elastin degradation accumulates quietly over time, shaping how skin functions long before changes fully register in the mirror.In this Biohacking Beauty episode, we unpack why rebuilding elastin is largely a myth, how elastin breakdown differs fundamentally from collagen loss, and how even a single period of stress can influence skin integrity for decades.We also examine how collagen is over-credited in conversations about sagging and how lasers and radiofrequency treatments can create temporary tightening while promoting long-term fibrotic remodeling that undermines true elasticity. Tune in.What's Discussed:(05:58) Why Elastin, Not Collagen, Drives Skin Bounce and Elastic Recovery(07:54) Elastin’s 70-Year Half-Life and Why Skin Aging Is Mostly About Preservation(11:39) Why Rebuilding Elastin Is Largely a Myth After Puberty(21:10) Why Collagen Loss Is Over-Credited in Skin Sagging(23:12) Lasers, RF and Fibrotic Remodeling vs True Skin Elasticity(26:50) The Elastin Enemies: UV, Oxidative Stress, Glycation and Inflammation(31:39) Preservation Over Correction: Building a Daily Elastin-Protective Strategy(34:01) Signal-Based Remodeling: Supporting Elastic Function Without Chronic InflammationFind more from Young Goose:VAMPIRE EXOSOMES: Professional Exosome Serum for Regeneration and Post-Treatment RecoveryUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at www.younggoose.com    Instagram: @young_goose_skincareFind our Winter Protocol here: https://www.younggoose.com/pages/winter-protocolFind our Elastin Action Protocol here: https://www.younggoose.com/pages/elastin-action-protocol-landing

Most conversations about advanced skin treatments stay at the surface, particularly around regenerative approaches, overlooking why lasting results are so hard to achieve.We dive deeper into this in the latest Biohacking Beauty episode with Dylan Gemelli. We explore why oral peptides often fall short, and how BPC-157 relates to gut healing, inflammation resolution, and collagen repair. We also unpack the real mechanism behind PRP facials, and how neuromodulating peptides compare to Botox over the long term.Dylan Gemelli is a prominent figure in the fitness and biohacking space and the host of the Dylan Gemelli Podcast. He is currently completing a master’s degree in dietetics and holds certifications as an integrative health professional and cellular health advisor, with his work centered on educating audiences about peptides, longevity, cellular health, nutrition, and neuroscience.What's Discussed:(09:07) The real risks of peptides, lack of regulation, and why quality matters(25:56) BPC-157 beyond athletics: gut healing, inflammation resolution, and collagen repair(29:44) Why injectable peptides outperform oral and one-off aesthetic treatments(32:51) Why consistency and loading phases determine peptide results(37:00) GHK-Cu and why copper peptides matter for skin, hair, and tissue repair(46:32) Neuromodulating peptides vs Botox and long-term wrinkle prevention(51:21) PRP facials work because of exosomes, not needlesFind more from Young Goose:VAMPIRE EXOSOMES → Professional Exosome Serum for Regeneration and Post-Treatment Recovery → Vampire ExosomesUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at www.younggoose.com    Instagram: @young_goose_skincareFind out everything you need to know about our Winter Protocol here: https://www.younggoose.com/pages/winter-protocol Find more from Dylan Gemelli:Website: www.dylangemelli.comInstagram: @dylangemelli

Ever wonder why your skin changes so much in winter? In this episode of Biohacking Beauty, we explain what actually happens when humidity drops, TEWL rises and indoor heating pulls moisture from the skin. We also talk about UVA exposure in cold months, lifestyle shifts that increase oxidative stress and why winter puts more pressure on your skin’s repair systems.We break down the winter ingredients that matter most, like ceramides, barrier lipids, vitamin F, beta glucan, hyaluronic acid, peptides, NAD precursors and exosomes, and how to use them in a routine that supports barrier strength and cellular energy. We also share simple protocol adjustments for different climates and biological skin ages.If you want a clear strategy for keeping your skin healthy and supported through the colder months, this episode gives you everything you need.What's Discussed:(00:36) How Winter Alters Skin Biology and Accelerates Aging(03:01) TEWL and Barrier Breakdown: Why Skin Gets Drier and More Reactive(06:26) The Hidden Winter Risk: UVA, Snow Reflection and Daily SPF Needs(12:47) Glycation, Inflammaging and NAD Decline During Winter(15:18) Essential Winter Ingredients: Ceramides, Lipids, Vitamin F and Smart Hydration(21:43) Longevity Actives: NAD Precursors, Peptides, Exosomes and Mitochondrial Support(28:11) Building the Winter Routine: Climate Adjustments and Repair Protocols(37:41) Tiered Protocols for Every Age: 30s, 40s, 50s and BeyondLinks Mentioned in This Episode: Watch our Instagram Reel on Red Light Therapy here!You can find Young Goose's Winter Protocol here!Find more from Young Goose:VAMPIRE EXOSOMES: Professional Exosome Serum for Regeneration and Post-Treatment RecoveryUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at www.younggoose.com Instagram: @young_goose_skincare

What if fine lines, breakouts, and flare-ups are not just skin issues, but the body replaying old experiences it never got to resolve? In this episode, we explore how nervous system patterns, unresolved emotion, and the way we hold stress in the body can quietly shape how our skin ages over time. We look at the skin as a boundary, a canvas, and a reflection of how safe we feel in the world.We talk with practitioner Eva Hooft about psychosomatics, face mapping, and the cell danger response, and how a chronically dysregulated system keeps inflammation and premature aging on a loop. Eva explains how somatic work can shift bowel function, circulation, and visible radiance, and why she often sees the liver and drainage as the missing link in chronic skin problems. We also dig into mineral balance, heavy metals, community, and why sustainable protocols have to respect both physiology and emotion.Eva Hooft is a somatic and detox practitioner who combines nervous system work, subconscious reprogramming, and mineral-based detox to help clients unwind chronic symptoms from the inside out. Through group programs, one-to-one work, and education, she guides people to build safety in the body, restore drainage, and release stored burdens so their health and skin can reflect a more regulated state.We Also Discuss:(00:54) How Unresolved Emotion Shows Up on the Skin(08:23) The Cell Danger Response and Chronic Inflammation(13:25) Somatic Practices That Shift Physical Health(19:41) Liver Congestion, Bowel Health, and Clear Skin(24:28) Mineral Balance, Heavy Metals, and Nervous System Stress(30:27) Community, Safety, and the Biology of Healing(34:27) Blending Subconscious Work with Detox Protocols(38:19) Botox, Natural Alternatives, and Sustainable BeautyFind more from Young Goose:Vampire Exosomes → Professional Exosome Serum for Regeneration and Post-Treatment Recovery Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://www.younggoose.com/    Instagram: @young_goose_skincareFind more from Eva Hooft:Instagram: @eva.hooftWebsite: evahooft.com

Everyone is chasing the next skincare hack, yet true beauty begins far deeper than a product. It grows through awareness, alignment, and how we move through life.In this episode, we sit down with beauty expert and coach Liz Kennedy to explore how biohacking, mindset, and consciousness work together to create what she calls magnetic beauty. We discuss how affirmations, community, and daily rituals strengthen your energy, as well as how outer practices such as peptides, NAD, and red light therapy enhance results when your inner world is balanced.Liz explains her approach to conscious biohacking and shares why practices like grounding, movement, and SPF are essential for long-term radiance. She also reveals how to integrate micro habits, her “pockets of peace” into modern routines while staying consistent, realistic, and connected.Liz Kennedy is a celebrity beauty expert, coach, and speaker who merges skincare science with consciousness and community. Through her events, workshops, and social media, she helps women cultivate beauty that reflects vitality, confidence, and purpose.We Also Discuss:(00:54) The Real Meaning of Magnetic Beauty and Conscious Biohacking(03:14) How Energy, Mindset, and Confidence Shape Physical Beauty(08:00) Daily Habits That Boost Radiance: Movement, SPF, and Grounding(12:20) Why Community and Female Connection Regulate Stress and Longevity(20:39) Aging with Power: Reframing How We See Time and Self-Love(31:14) Integrating Affirmations and Skincare for Emotional Resilience(34:13) The Truth About Peptides, NAD, and At-Home Biohacking(44:29) Cold Plunge Controversy: Why Some Methods May Disrupt Female BalanceFind more from Young Goose:Blue Peptide Spray: Cellular hydration meets antioxidant power Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://www.younggoose.com/    Instagram: @young_goose_skincareFind more from Liz Kennedy:Instagram: @ Liz Kennedy TikTok: lizkennedy__ Facebook: Liz Kennedy 

Many listeners asked us to go deeper into exosomes, and this episode expands on everything that most brands avoid talking about: count, consistency, purity, and microRNA composition. We explain why exosomes on a label don’t mean much without verified numbers, and how dose shapes whether the skin actually receives a biologically meaningful message.We walk through why platelet-derived exosomes offer the clearest communication to human skin, why microRNAs matter more than growth factors alone, and how publishing full sequencing data creates a new standard for transparency in longevity skincare. We also explore the synergy between exosomes and NAD+, how cellular energy drives repair, and why combining messenger and fuel creates a regenerative loop the skin can sustain.This episode gives listeners a clear, science-driven understanding of how exosome formulas should be evaluated and what truly defines high-performance regenerative skincare.As founders of Young Goose Skincare, we focus on bringing advanced longevity science into daily routines through transparency, validated potency, and clinically guided innovation.We Also Discuss:(00:19) Why “Exosomes on the Label” Tells You Almost Nothing(01:48) The Dose Problem: How Most Exosome Serums Miss Biological Activity(03:11) Why microRNA is the Real Engine Behind Skin Repair(05:16) The Transparency Gap in Skincare, and How We’re Closing It(09:21) Exosomes as Messages, NAD+ as the Battery(12:21) Clearing Senescent Cells and Restoring Youthful FunctionFind more from Young Goose:VAMPIRE EXOSOMES → Professional Exosome Serum for Regeneration and Post-Treatment Recovery → Vampire ExosomesUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://www.younggoose.com/    Instagram: @young_goose_skincare

Many listeners have been curious about exosomes, and this episode offers a simple, science-based foundation for understanding them. We explore what exosomes are, how they act as communication packets between cells, and why they play such an important role in skin rejuvenation.We walk through the three main categories of exosomes found in skincare, plant, stem cell, and platelet-derived,  and discuss how each behaves differently inside the skin. We explain what happens when cellular signals weaken with age, what we’ve learned through PRP and regenerative medicine, and why not every exosome speaks the same biological language. We also touch on dose, purity, and consistency, which shape how effective an exosome formula can be.This episode gives listeners a clear, approachable starting point for navigating this rapidly growing area of skincare and understanding what truly supports long-term repair.As founders of Young Goose Skincare, we focus on bringing advanced regenerative science into everyday skincare through education and clinically guided innovation.We Also Discuss:(00:00) Integrating Dermatology, Health Optimization, and Longevity Medicine(04:38) How Skin Both Reflects and Influences Systemic Health(08:39) The Connection Between Stress, Cortisol, and Skin Function(10:17) Clarifying Sunscreen Science, Hormonal Changes, and Menopause(13:51) Defining True Prejuvenation and the Role of Softwave Technology(19:40) Exploring RLX201 (ReQ) and Innovations in Skin Longevity(32:20) Linking Inflammation, Oxidative Stress, and Visible Aging(37:56) Applying Critical Thinking to the Future of Longevity Medicine(46:18) Rethinking Fillers, Structural Balance, and Subtle Aesthetic Enhancement(58:42) Building Longevity Habits for Lifelong Skin HealthFind more from Young Goose:VAMPIRE EXOSOMES → Professional Exosome Serum for Regeneration and Post-Treatment Recovery → Vampire ExosomesUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://www.younggoose.com/    Instagram: @young_goose_skincare