Up2

Seven years after her first visit to the Up2 studio, our favorite public company CEO,  Sheryl Palmer returns following the announcement that the esteemed Berkshire Hathaway is acquiring Taylor Morrison for nearly $7 billion. In this wide-ranging conversation, she reflects on what drew Berkshire to TM, the power of combining multiple homebuilders under one platform, and her vision for delivering better housing solutions at greater scale.  Sheryl also discusses her personal leadership philosophy, the influence of early mentors like Ray Kroc (McDonald's), and how she stays grounded while leading through major transformation. She shares thoughts on innovation in homebuilding, the importance of community, and balancing a high-impact career with family life.

Ben duPont grew up with one of the most recognizable last names in American business — but he chose to forge his own path beyond the family empire. And while most of us don't know what it's like to have our name as a brand, many of us do know what it's like to consider following our family's expectations or chart our own course. In this wide-ranging conversation, the co-founder of Yet2 and partner at Chartline Capital Partners shares how he left the duPont company to pioneer open innovation, why he’s more optimistic than ever about the future, and what’s really changing in the age of AI. Ben breaks down the key difference between the last tech wave and today.

In perhaps the most personal and emotionally raw episode of Up2 ever released, host Adam Kaufman shares the full, never-before-publicly-heard 2001 AA convention speech given by his late father, Bill Kaufman. Recorded live in Myrtle Beach, SC  in 2001— about one year before Bill passed away —this is more than a recovery story. It is a heartfelt confession, a stand-up comedy routine, a raw apology, and a profound testimony of hope, all wrapped into one unforgettable hour.  Another Up2 guest, Special Ambassador Doug Holladay, likes to remind us that "we're all born into someone else's story." Here we learn about the story our host was born into....  This episode is for anyone who has struggled with addiction, loved someone who has, or simply needs to be reminded that no one is beyond redemption. It is funny, heartbreaking, and deeply inspiring all at once.

In this inspiring episode of the Up2 Podcast, host Adam sits down with Dr. Rene Caissie — a former maxillofacial surgeon, department chief, and repeat entrepreneur — who left a successful medical career in Canada to found Medeloop, an AI-native platform that deploys intelligent agents on massive healthcare datasets to accelerate clinical research, discover new biomarkers, reduce costs, and improve operational efficiency in hospitals and life sciences. Dr. Caissie shares his remarkable journey: building and exiting an EMR company, moving his family to Silicon Valley, studying at Stanford GSB, and now leading a fast-growing AI health tech company valued at over $100 million. He opens up about the emotional side of entrepreneurship, the importance of relationships, managing board pressure, staying grounded through extreme hobbies and family life, and why he believes AI will fundamentally transform how medicine is practiced. A must-listen for physicians, entrepreneurs, healthcare leaders, and anyone fascinated by the intersection of AI and medicine.

What does it feel like to sell your company after toiling and growing your 'baby'for more than 30 years? Fred Koury made the big decision to sell his successful Smart Business company less than a year ago, and we were fortunate to earn his trust and have him sit with us to discuss not only that exit but also what he's Up2 now.    On special location at the comfy VividFront studio, tune in to get inside the impressive mind and big heart of one highly regarded human being.