Thinkers50 Podcast

What if healthcare focused more on health – not simply on delivering care? Physician executive and global health strategist Nasim Afsar argues that today’s healthcare system sees only a fraction of the person it is trying to help. Healthcare delivery accounts for around 20% of what determines our health, she says; the other 80% lies in factors such as what we eat, how we live, our stress, habits, environment, and genetics. Yet these different streams of information rarely come together. The author of Intelligent Health, Nasim explores how unifying that data could enable a shift towards healthcare that is personalized, predictive, preventative, and participatory – focused on people’s life goals rather than simply their clinical measures. AI could help turn an abundance of fragmented data into meaningful insights, while creating opportunities for clinicians to spend more time on the human elements of medicine: connection, judgement, and trust. But AI is no panacea. Nasim argues that applying powerful new technology will likely deliver only incremental gains. She suggests starting by deciding what kind of health system we want to create – and then using AI, with intentionality, as one of the tools to build it. --- This podcast is part of an ongoing series of interviews with executives. The executives’ participation in this podcast are solely for educational purposes based on their knowledge of the subject and the views expressed by them are solely their own. This podcast should not be deemed or construed to be for the purpose of soliciting business for any of the companies mentioned, nor does Deloitte advocate or endorse the services or products provided by these companies.

Hamilton Mann argues that one of the most urgent challenges posed by AI is the concentration of algorithmic power. He identifies three layers: capability, as a small number of companies develop powerful AI systems; distribution, as those systems reach millions of people; and, most consequentially, governance, where some algorithmic systems can increasingly shape decisions, allocate resources, and determine outcomes. Conventional technology regulation is not enough, Hamilton says. AI governance should be a question of constitutional thinking – asking not simply what rules powerful systems should obey, but where their legitimacy comes from. Hamilton is the author of a new book Trias Algorithmica: What Code Rules and Artificial Integrity, which was named a Thinkers50 Top 10 Best Management Book for 2025. He also received the 2025 Thinkers50 Digital Thinking Award, following his induction into the Thinkers50 Radar in 2024. --- This podcast is part of an ongoing series of interviews with executives. The executives’ participation in this podcast are solely for educational purposes based on their knowledge of the subject and the views expressed by them are solely their own. This podcast should not be deemed or construed to be for the purpose of soliciting business for any of the companies mentioned, nor does Deloitte advocate or endorse the services or products provided by these companies.

What happens when the biggest risk to business isn’t in the model? Most financial models have a silent assumption buried at their core: that the climate will stay stable. Spencer Glendon spent nearly two decades in investment research identifying what others missed. His search for hidden assumptions led him to discover that climate stability underpins virtually every business model, yet most leaders still treat climate as a specialist issue rather than a core strategic concern. In conversation with Des Dearlove and Steve Goldbach, Spencer explores: • why climate belongs in the boardroom, not in a box • why markets have been so slow to price climate risk • how to turn abstract climate science into practical decisions As the founder of Probable Futures, Spencer translates complex climate models into accessible tools, helping leaders understand probable future, rather than distant challenges or apocalyptic scenarios. --- This podcast is part of an ongoing series of interviews with executives. The executives’ participation in this podcast are solely for educational purposes based on their knowledge of the subject and the views expressed by them are solely their own. This podcast should not be deemed or construed to be for the purpose of soliciting business for any of the companies mentioned, nor does Deloitte advocate or endorse the services or products provided by these companies.

What if the biggest problem with marketing today is the way we’ve been taught to think about it? Samuel Monnie, once a “reformed marketer” but now “marketing reformer,” argues that traditional marketing frameworks like the 4Ps (product, price, place, promotion) no longer reflect the world we live in. Instead, we should look towards a more human model: purpose, people, progress, and prosperity. Purpose: driving more inclusive, equitable outcomes – and positive impact People: leading with compassion, creativity, and connection Progress: creating better solutions that raise the bar for everyone Prosperity: building systems where business, society, and nature can thrive In this episode he explains why aligning business with values is not just ethical but a commercial imperative. He brings the data to dispel the myth that profit and purpose are in conflict. And explores how organizations can “learn, unlearn, and relearn,” embracing curiosity, listening more deeply to customers and employees, and focusing on progress over perfection. Samuel is co-founder and co-CEO of New York-based Purpose Hive. He has led brand and business growth at companies including Braun, Campbell's, Grainger, Safeway, Proctor & Gamble, and Sustainable Brands. --- This podcast is part of an ongoing series of interviews with executives. The executives’ participation in this podcast are solely for educational purposes based on their knowledge of the subject and the views expressed by them are solely their own. This podcast should not be deemed or construed to be for the purpose of soliciting business for any of the companies mentioned, nor does Deloitte advocate or endorse the services or products provided by these companies.

What if the real purpose of business is not simply to make money, but to serve humanity? André Hoffmann is vice chairman of Roche Holding, co-founder of Intent, board member of the World Economic Forum, and co-author of The New Nature of Business: The Path to Prosperity and Sustainability. In this rich conversation with Thinkers50 CEO Mikko Leskelä and Kulleni Gebreyes, vice chair and US life sciences and healthcare industry leader at Deloitte, André challenges the traditional view that financial capital alone defines success. Instead, leaders must recognise: • Three other forms of capital: natural, social, and human • Why being an environmentalist and a capitalist is not a contradiction • Nature is our life support system; if we destroy it, we destroy ourselves • It's not how you spend the money that matters, it's how you make it • Business should and can be a force for good in solving humanity’s biggest problems Discover how leaders can align profit and purpose, prosperity and sustainability, and ultimately become good ancestors. --- This podcast is part of an ongoing series of interviews with executives. The executives’ participation in this podcast are solely for educational purposes based on their knowledge of the subject and the views expressed by them are solely their own. This podcast should not be deemed or construed to be for the purpose of soliciting business for any of the companies mentioned, nor does Deloitte advocate or endorse the services or products provided by these companies.