Saving Lives In Slow Motion

Parkinson’s Disease (PD) affects more people every year with a global increase in ageing populations. There is no cure for the condition but medication can alleviate symptoms. In this episode I look at the causes of the disease and what we can do to prevent it. Your opinion matters. SURVEY here - please help me by taking this 10 minute survey -thank you!: http://bit.ly/savinglivesinslowmotion-surveyThe Parkinson's pandemic: https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(20)30302-1/fulltextGut-brain link: https://pmc.ncbi.nlm.nih.gov/articles/PMC10358673/REM sleep behaviour disorder: https://my.clevelandclinic.org/health/diseases/24465-rem-sleep-behavior-disorder-rbdPer Borghammer - body-first and brain first model: https://www.youtube.com/watch?v=mVew2OVZTXsGenes in PD: https://www.hopkinsmedicine.org/health/conditions-and-diseases/parkinsons-disease/the-genetic-link-to-parkinsons-diseaseLeaky gut in Parkinsons Disease: https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(25)00240-3/fulltextCoeliac Disease, gluten sensitivity and Parkinson’s Disease link (a literature review): https://pmc.ncbi.nlm.nih.gov/articles/PMC12011982/H pylori and Parkinson’s Disease: https://immunityageing.biomedcentral.com/articles/10.1186/s12979-023-00404-1Diet: https://www.healthline.com/health/parkinsons-and-dietExercise - tai chi: https://www.bbc.co.uk/news/health-67208745Iron overload: https://www.aan.com/PressRoom/home/PressRelease/30Vitamin D: https://www.sciencedirect.com/science/article/pii/S2667268523000499Pesticides: https://www.uclahealth.org/news/release/researchers-identify-10-pesticides-toxic-neurons-involvedRotenone (insecticide) and PD: https://www.nature.com/articles/s41531-023-00561-6Save your life in slow motion and those of others by subscribing now and sharing. Thank you for listening and for your support. It means a lot to me. Hosted on Acast. See acast.com/privacy for more information.

Vaccines are often the subject of heated discussion. In this episode I share some thoughts on the topics as it affects us all and needs handling sensitively.Your opinion matters. SURVEY here - thank you!: http://bit.ly/savinglivesinslowmotion-surveyEdward Jenner and vaccine discovery: https://www.jenner.ac.uk/about/edward-jennerA broad overview: https://www.who.int/news-room/spotlight/history-of-vaccination/a-brief-history-of-vaccinationCommon short term side effects of vaccines: https://assets.publishing.service.gov.uk/media/5dfa14bfed915d54aca2b837/PHE_what_to_expect_after_vaccination_English.pdfOld Friends Hypothesis: https://www.news-medical.net/health/Old-Friends-Hypothesis.aspxHerd Immunity explained: https://vaccineknowledge.ox.ac.uk/herd-immunityVaccine hesitancy: https://www.bbc.co.uk/news/articles/c1jgrlxx37doMeasles in the USA: https://www.health.harvard.edu/blog/measles-is-making-a-comeback-can-we-stop-it-202503063091Vaccine injury cases: https://www.bbc.co.uk/news/articles/c4gzleyydp8o#Neanderthal genes and COVID: https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3673483Decision making and vaccines: https://www.sciencedirect.com/science/article/pii/S0264410X25004311Travel vaccines: https://travelhealthpro.org.uk/Save your life in slow motion and those of others by subscribing now and sharing. Thank you for listening and for your support. It means a lot to me. Hosted on Acast. See acast.com/privacy for more information.

In this episode I look at this big question which I often hear in the consulting room, the reasons that lie behind it and what the point to life might be.Your opinion matters. SURVEY here - thank you!: http://bit.ly/savinglivesinslowmotion-surveyNihilism in philosophy: https://www.learnreligions.com/what-is-nihilism-history-250581Cosmic Insignificance: https://pmc.ncbi.nlm.nih.gov/articles/PMC4340547/Maslow’s Hierarchy of Needs: https://www.bitesizelearning.co.uk/resources/maslows-hierarchy-of-needs-theoryAcceptance and Commitment Therapy: https://therisingsuncounseling.com/acceptance-and-commitment-therapy-a-framework-for-a-meaningful-life-copy/Four Thousand Weeks by Oliver Burkeman: https://www.oliverburkeman.com/fourthousandweeksThe science behind gratitude: https://positivepsychology.com/neuroscience-of-gratitude/The benefits of volunteering: https://www.royalvoluntaryservice.org.uk/volunteering/why-volunteer/benefits-of-volunteering/Ways to ask for help if you struggle to: https://www.wondermind.com/article/asking-for-help/Save your life in slow motion and those of others by subscribing now and sharing. Thank you for listening and for your support. It means a lot to me. Hosted on Acast. See acast.com/privacy for more information.

Continuity of care saves lives. There is evidence that outcomes are improved and itused to be a core part of medicine. In recent years for many reasons continuity has been slightly eroded. In this episode I make the case for it and give examples of why it can beof critical importance.Links:Please help me improve my content for you by taking this audience survey which takes 10 minutes:http://bit.ly/savinglivesinslowmotion-surveyStudy on continuity and outcomes: https://bjgp.org/content/72/715/e84How seeing the same doctor has changed in the UK: https://www.bmj.com/content/389/bmj.r833Patient examples of the benefits: https://www.nuffieldtrust.org.uk/news-item/the-importance-of-continuity-four-personal-viewpointsSave your life in slow motion and those of others by subscribing now and sharing. Thank you for listening and for your support. It means a lot to me. Hosted on Acast. See acast.com/privacy for more information.

PCOS is a growing global issue. Its prevalence has increased in recent years and the reasons behind it are complex.In this episode I look at its roots, causes and impact plus what we can do about it in terms of lifestyle and treatments.Links: Depression and PCOS: https://pmc.ncbi.nlm.nih.gov/articles/PMC10607337/LH (luteinziing hormone): https://my.clevelandclinic.org/health/body/22255-luteinizing-hormoneLH:FSH ratio in PCOS: https://gpnotebook.com/en-GB/pages/gynaecology/polycystic-ovarian-syndrome-hormonal-measurements-inPancreatic function in PCOS: https://pmc.ncbi.nlm.nih.gov/articles/PMC9962893/The gut microbiome and PCOS: https://pmc.ncbi.nlm.nih.gov/articles/PMC9998696/The steroid synthesis pathway starting with cholesterol: https://www.researchgate.net/figure/Biosynthesis-of-steroid-hormones-from-the-cholesterol-pathway_fig1_258055538Angelique Panagos book on hormonal balance: https://www.amazon.co.uk/Balance-Plan-Optimize-Hormonal-Health/dp/1844039447Save your life in slow motion and those of others by subscribing now and sharing. Thank you for listening and for your support. It means a lot to me. Hosted on Acast. See acast.com/privacy for more information.

In this episode I look at metabolic health which is one of the most important aspects of our long term health. I look at the mechanisms and measures of metabolic health and what we can do to improve ours.Continuous Glucose Monitoring: https://my.clevelandclinic.org/health/articles/continuous-glucose-monitoring-cgmHba1c: https://www.diabetes.org.uk/about-diabetes/looking-after-diabetes/hba1c#American metabolic health stats: https://www.liebertpub.com/doi/10.1089/met.2018.0105High fructose corn syrup; https://www.healthline.com/nutrition/why-high-fructose-corn-syrup-is-badFibre in your diet: https://www.healthline.com/nutrition/why-is-fiber-good-for-youExercise and metabolic health: https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2024.1365761/fullMetabolic health and Alzheimer's risk: https://pmc.ncbi.nlm.nih.gov/articles/PMC10001958/Non-communicable diseases: https://www.who.int/news-room/fact-sheets/detail/noncommunicable-diseasesSave your life in slow motion and those of others by subscribing now and sharing. Thank you for listening and for your support. It means a lot to me. Hosted on Acast. See acast.com/privacy for more information.

In this episode I cover my own personal tips from the view point of a GP and lifestyle medicine doctor. Gut symptoms Around 86% of us in the UK have experienced gut symptoms at some point. My tips are simple, for everyone and hopefully make sense.Parasympathetic drive for digestion: https://www.livescience.com/parasympathetic-nervous-system-rest-and-digestDigestive enzymes: https://www.webmd.com/diet/what-are-digestive-enzymesBlue Zones eating habits: https://www.bluezones.com/2020/07/blue-zones-diet-food-secrets-of-the-worlds-longest-lived-people/Mediterranean Diet: https://my.clevelandclinic.org/health/articles/16037-mediterranean-dietLate night eating: https://hms.harvard.edu/news/late-night-eating-impactTime restricted eating: https://www.healthline.com/nutrition/time-restricted-eatingIleo-caecal valve issues: https://www.carygastro.com/blog/what-are-the-symptoms-of-a-faulty-ileocecal-valveHydration and the gut (an academic paper): https://www.sciencedirect.com/science/article/pii/S2589004224011258Buy my book The Health Fix now: https://www.amazon.co.uk/Health-Fix-Dr-Ayan-Panja/dp/1914239326/ref=tmm_pap_swatch_0Save your life in slow motion and those of others by subscribing now and sharing. Thank you for listening and for your support. It means a lot to me. Hosted on Acast. See acast.com/privacy for more information.

Chronic inflammation is a key process which is linked to almost all non-communicable disease. In this episode I look at how it arises and why it is so harmful.Links: Age-related end glycation products: https://www.healthline.com/nutrition/advanced-glycation-end-products#what-they-are'Leaky gut’ syndrome: https://pmc.ncbi.nlm.nih.gov/articles/PMC8305009/Depression as an inflammatory condition: https://www.sciencedirect.com/science/article/pii/S1043661824002676Probitoics after antibiotics?: https://www.bbc.com/future/article/20190124-is-it-worth-taking-probiotics-after-antibioticsDiabetes and inflammation: https://www.webmd.com/diabetes/inflammation-and-diabetesInflammation from toxins (metals and brain inflammation): https://www.sciencedirect.com/science/article/abs/pii/S2468202021000127Anti-inflammatory diet: https://www.hopkinsmedicine.org/health/wellness-and-prevention/anti-inflammatory-dietFibre: https://dremilyleeming.substack.com/p/is-fibre-the-missing-link-to-trueOmega-3 and inflammation: https://pubmed.ncbi.nlm.nih.gov/37606147/Save your life in slow motion and those of others by subscribing now and sharing. Thank you for listening and for your support. It means a lot to me. Hosted on Acast. See acast.com/privacy for more information.

What do surgery and psychiatry have in common? They are both demanding specialties, occasionally of last resort, that save lives acutely and help people back to better health.LinksAntipsychotic drug discovery: https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2022.903156/fullPyrrole Disorder: https://www.healthline.com/health/pyrrole-disorder#diagnosisRationing in the NHS: https://www.kingsfund.org.uk/insight-and-analysis/blogs/nhs-rationing-under-the-radarAn example of risks vs benefit in surgery: https://www.neurosurgeonsofnewjersey.com/blog/spinal-fusion-surgery-risks/Save your life in slow motion and those of others by subscribing now and sharing. Thank you for listening and for your support. It means a lot to me. Hosted on Acast. See acast.com/privacy for more information.

There are so many posts, papers and publications about the vagus nerve.In this episode I look at why it’s so popular and whether it really can be a key to future treatments with advances vagus nerve stimulation.Links: Quick overview: https://www.mayoclinic.org/tests-procedures/vagus-nerve-stimulation/about/pac-20384565Polyvagal Theory: https://www.polyvagalinstitute.org/whatispolyvagaltheoryThe Great Nerve: https://www.amazon.co.uk/Great-Nerve-Science-Harness-Reflexes/dp/059371699XResearch on the vagus and rheumatoid arthritis: https://pubmed.ncbi.nlm.nih.gov/27382171/Ear stimulation: https://medicine.ouhsc.edu/news/article/ear-clip-stimulation-of-vagus-nerve-shows-promise-as-pots-treatment-according-to-ou-college-of-medicine-studyVasovagal attacks: https://my.clevelandclinic.org/health/diseases/23325-vasovagal-syncopeCrohn’s Disease and vagus nerve stimulation: https://pubmed.ncbi.nlm.nih.gov/32515156/Vagus nerver and inflammation: https://bioelecmed.biomedcentral.com/articles/10.1186/s42234-022-00100-3Save your life in slow motion and those of others by subscribing now and sharing. Thank you for listening and for your support. It means a lot to me. Hosted on Acast. See acast.com/privacy for more information.

Medicine is an inexact science. My patients who are engineers find it frustrating that there is so much conjecture and educated guess work in medicine. But this episode highlights why diagnoses can take time. It’s a mix of detective work, bias and listening to the patient story.Links:Chilblains: https://www.mayoclinic.org/diseases-conditions/chilblains/diagnosis-treatment/drc-20351103STI and painful knee: https://www.medicalnewstoday.com/articles/gonococcal-arthritisCarpal tunnel syndrome: https://orthoinfo.aaos.org/en/diseases--conditions/carpal-tunnel-syndrome/Psychodermatology (the mind-skin link): https://www.psychodermatology.co.uk/Liver inflammation and glandular fever: https://www.healthline.com/health/mono-hepatitisSave your life in slow motion and those of others by subscribing now and sharing. Thank you for listening and for your support. It means a lot to me. Hosted on Acast. See acast.com/privacy for more information.

Not a week goes by in practice where I don’t see a patient who hasn’t collapsed or had a dizzy spell.There are so many reasons for this, some preventable, some not. I look at some of the syndromes that lead to these issues.Links:Fainting: https://www.healthline.com/health/fainting#causesPseudoseizures (non-eplieptic seizures): https://my.clevelandclinic.org/health/diseases/24517-psychogenic-nonepileptic-seizure-pnesAbsence seizures: https://www.mayoclinic.org/diseases-conditions/petit-mal-seizure/symptoms-causes/syc-20359683Epilepsy and driving: https://www.gov.uk/epilepsy-and-drivingBPPV (a type of vertigo): https://my.clevelandclinic.org/health/diseases/11858-benign-paroxysmal-positional-vertigo-bppvPatient perspective of Mal de Debarquement syndrome: https://www.rarediseaseday.org/heroes/a-uk-patient-perspective-on-mal-de-debarquement-syndrome/Heartblock: https://www.nhs.uk/conditions/heart-block/Gluten ataxia: https://www.medicalnewstoday.com/articles/320730Proprioception: https://my.clevelandclinic.org/health/articles/proprioceptionSave your life in slow motion and those of others by subscribing now and sharing. Thank you for listening and for your support. It means a lot to me. Hosted on Acast. See acast.com/privacy for more information.

5-15% of GP consultations are linked to tiredness. And the number is growing. In this episode I look at common and rarer reasons for tiredness. Hydration - if you’re feeling thirsty you’re partly dehydrated: https://www.nhsinform.scot/illnesses-and-conditions/nutritional/dehydration/Sleep apnoea: https://www.mayoclinic.org/diseases-conditions/sleep-apnea/symptoms-causes/syc-20377631Breathing to help some root causes of fatigue: https://buteykoclinic.com/blogs/buteyko-breathing-technique/buteyko-breathing-techniqueMycotoxin illness: https://www.parsleyhealth.com/blog/mold-toxicity-symptoms/Co-enzyme Q10: https://bjcardio.co.uk/2015/10/coenzyme-q10-and-cardiovascular-disease-an-overview/Antibiotic tiredness: https://www.medicalnewstoday.com/articles/do-antibiotics-make-you-tiredBurnout: https://mentalhealth-uk.org/burnout/Save your life in slow motion and those of others by subscribing now and sharing. Thank you for listening and for your support. It means a lot to me. Hosted on Acast. See acast.com/privacy for more information.

Teenage and adolescent health offers us a glimpse into the future health of the world. The Lancet Commission wrote a report in 2016 and have recently written a follow up which paints a slightly concerning picture.In this episode I look at health in this group of people, the challenges they face and what, if anything, can be done about it.Links:The Lancet Commission report summary: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00863-3/fulltextBarriers to healthcare for adolescents: https://pmc.ncbi.nlm.nih.gov/articles/PMC8070789/Global numbers: https://www.who.int/news-room/fact-sheets/detail/adolescents-health-risks-and-solutionsOmega-3 and brain health: https://pubmed.ncbi.nlm.nih.gov/35960396/Climate Stress: https://pmc.ncbi.nlm.nih.gov/articles/PMC10154789/Free tips from Annette Du Bois (teenage coach): https://www.champs-academy.co.uk/free-help-and-support/Save your life in slow motion and those of others by subscribing now and sharing. Thank you for listening and for your support. It means a lot to me. Hosted on Acast. See acast.com/privacy for more information.

In this episode I look at our health compared to 100 years ago. I was pleasantly surprised at some similarities having stumbled across something online but then also appreciate that we live in a different world now. Links: Donald Moore’s health habits in 1925: https://archive.org/details/health.habits.moore.1925/page/n1/mode/2upAdventist health: https://www.bluezones.com/explorations/loma-linda-california/Health in the 1920s: https://www.encyclopedia.com/social-sciences/culture-magazines/1920s-medicine-and-health-overviewTech neck: https://sharpphysiotherapy.co.uk/the-hidden-dangers-of-tech-neck/Pesticides and human health: https://pmc.ncbi.nlm.nih.gov/articles/PMC11426366/Mycotoxin illness: https://pmc.ncbi.nlm.nih.gov/articles/PMC8619365/Toxic productivity: https://hbr.org/2024/11/lets-end-toxic-productivitySave your life in slow motion and those of others by subscribing now and sharing. Thank you for listening and for your support. It means a lot to me. Hosted on Acast. See acast.com/privacy for more information.

In the UK, there is much discussion around assisted dying with a bill that is being voted on in government at the moment.In this episode I look at the ethics around it and what it might mean on an individual and societal level.Palliative Care: https://www.nhs.uk/tests-and-treatments/end-of-life-care/what-it-involves-and-when-it-starts/Dr Florian Willett’s death: https://www.independent.co.uk/news/world/europe/suicide-pod-activist-euthanasia-sarco-b2762514.htmlLocked-in syndrome: https://my.clevelandclinic.org/health/diseases/22462-locked-in-syndrome-lisHow assisted dying works in The Netherlands: https://www.theguardian.com/lifeandstyle/2015/sep/11/assisted-dying-dutch-end-of-life-netherlands-unbearable-sufferingTalking about death and dying: https://www.hospiceuk.org/information-and-support/death-and-dying-what-expect/about-death-and-dyingThe Humanists view: https://humanists.uk/2023/10/03/six-reasons-we-need-an-assisted-dying-law/The current state of affairs in the UK regarding the assisted dying bill: https://www.bbc.co.uk/news/articles/c5y5d2g3wgxoMy new website: https://drayan.co.uk/Save your life in slow motion and those of others by subscribing now and sharing. Thank you for listening and for your support. It means a lot to me. Hosted on Acast. See acast.com/privacy for more information.

Fasting is a hot but contentious topic. It has been practised for thousands of years and is now purported to be a way of tackling or preventing certain metabolic diseases. In this episode I look at the pros, cons and mechanisms of fasting. Links: Historical perspectives of fasting: https://pmc.ncbi.nlm.nih.gov/articles/PMC8838777/Time restricted feeding in mice (Sachin Panda): https://pmc.ncbi.nlm.nih.gov/articles/PMC3491655/Further study (see first image for feeding habits): https://www.sciencedirect.com/science/article/pii/S15504131140049875:2 diet summary: https://www.healthline.com/nutrition/the-5-2-diet-guideProlonged fasting: https://pubmed.ncbi.nlm.nih.gov/37377031/Fasting and autophagy: https://my.clevelandclinic.org/health/articles/24058-autophagyThe flip side - analysis of a study that found a increased link to heart disease from fasting: https://www.bhf.org.uk/informationsupport/heart-matters-magazine/news/behind-the-headlines/intermittent-fasting#Save your life in slow motion and those of others by subscribing now and sharing. Thank you for listening and for your support. It means a lot to me. Hosted on Acast. See acast.com/privacy for more information.

Every week or so you will see and article about one or more of these topics.Maybe you have tried them or do them regularly. In the episode I look at the science and thinking behind them all.Links: Cold water exposure - a paper: https://pmc.ncbi.nlm.nih.gov/articles/PMC9518606/Vagus nerve stimulation: https://my.clevelandclinic.org/health/treatments/17598-vagus-nerve-stimulationHyperbaric oxygen: https://www.hopkinsmedicine.org/health/treatment-tests-and-therapies/hyperbaric-oxygen-therapySaunas and potential benefits (academic paper): https://www.sciencedirect.com/science/article/pii/S0531556521002916#s0180High Protein Diet: https://www.healthline.com/nutrition/high-protein-diet-planBuy my book THE HEALTH FIX now: https://www.amazon.co.uk/Health-Fix-Dr-Ayan-Panja/dp/1914239326/ref=tmm_pap_swatch_0My new website: https://drayan.co.uk/Save your life in slow motion and those of others by subscribing now and sharing. Thank you for listening and for your support. It means a lot to me. Hosted on Acast. See acast.com/privacy for more information.

Prescribing Lifestyle Medicine is a course I run with Dr Rangan Chatterjee that has been going for 8 years now.It was the first course of its kind in the UK and in this episode I look at a recap of our recent conference, what has changed in lifestyle medicine over the years and the latest science.Links:Dr Emily Leeming: https://www.emilyleeming.com/Dr Rob Lustig: https://robertlustig.com/Dr Kiran Sodha: https://www.drsodha.co.uk/Dr Nathaniel Roocroft’s work: https://www.royalnavy.mod.uk/news/2023/november/23/20231123-uk-flagship-pioneers-largest-ever-mental-and-physical-health-drive-at-seaDr Madhvi Joshi: https://www.linkedin.com/in/madhvi-joshi-419b71353/Depression as an inflammatory disease: https://pubmed.ncbi.nlm.nih.gov/38826138/Gut-brain axis and the role of the microbiome in neurodegeneration: https://www.nature.com/articles/s41392-024-01743-1Fibre benefits: https://www.healthline.com/nutrition/why-is-fiber-good-for-youWeight loss drugs hold key to longer life?: https://www.thetimes.com/uk/healthcare/article/golden-age-of-medicine-weight-loss-drugs-seen-as-key-to-longer-life-3wblnx3j6#Prescribing Lifestyle Medicine:https://www.practiceunbound.org.uk/product/prescribinglifestylemedicine/homeSave your life in slow motion and those of others by subscribing now and sharing. Thank you for listening and for your support. It means a lot to me. Hosted on Acast. See acast.com/privacy for more information.

Ayurvedic Medicine is thousands of years old. It has a systems based approach which can be personalised and its methods are based on careful observation and the interconnectedness of human beings and our relation to our environment. There has also been caution around some treatments which can cause harm which I cover in this episode.A quick summary of Ayurvedic Medicine: https://www.nccih.nih.gov/health/ayurvedic-medicine-in-depthThe doshas: https://www.healthline.com/nutrition/vata-dosha-pitta-dosha-kapha-doshaPulse diagnosis: https://www.healingholidays.com/blog/pulse-diagnosis-in-ayurvedaLiver Disease in 14 year old: https://timesofindia.indiatimes.com/city/kochi/liver-failure-in-14-year-old-kerala-girl-leads-to-traditional-vs-modern-medicine-debate/articleshow/94822613.cmsAyurvedic herbs: https://www.healthline.com/nutrition/ayurvedic-herbsSave your life in slow motion and those of others by subscribing now and sharing. Thank you for listening and for your support. It means a lot to me. Hosted on Acast. See acast.com/privacy for more information.