The Heart of Healthcare | A Digital Health Podcast

Cancer drugs cost more than ever, yet survival benefits are often modest—and in some cases, patients can’t even access the care that already exists. After losing his father, Steve Jobs, to pancreatic cancer, Reed Jobs committed himself to making this the last generation that loses parents to the disease.Reed now leads Yosemite, a venture fund spun out of Emerson Collective in 2023, alongside Investor Matt Bettonville. Yosemite pairs life sciences and digital health investments with a grantmaking model to accelerate cancer research and ensure breakthroughs actually reach patients.We cover:📉 The tension between drug pricing, patient access, and real-world value🩺 Digital interventions that have outperformed cancer drugs in survival outcomes🧪 Why phase 3 clinical trials are so costly, and how synthetic control arms could change that🧬 The promise and limits of early detection—from liquid biopsies to at-home pap smears🌍 The global race for healthcare innovation and why the U.S. can’t afford to fall behindAbout our guests:Reed Jobs is an Investor at Yosemite and manages Yosemite. Yosemite works exclusively in the oncology space, using flexible capital to advance science with the goal of making cancer non-lethal in our lifetime. Over the years, Reed has supported hundreds of researchers and invested in dozens of therapeutic, diagnostic and digital health companies across the U.S. and Europe. Before the launch of Yosemite, Reed served as the Managing Director of Health at Emerson Collective. He serves on the board of directors at Conservation International, Harvard Medical School, PICI, Stanford Medicine and Waverley Street Foundation. Matt Bettonville is an Investor at Yosemite where he leads the team’s investment efforts in digital health and healthcare delivery. He previously worked on Emerson Collective’s Count Me In non-profit partnership with the Broad Institute. Matt started his career working on user interface software engineering at Apple, where he was on the Mac team and a part of the AirPods product team. He holds a B.S. in Computer Science from Stanford University with a focus in Human-Computer Interaction. Matt serves on the board of directors at Atropos, Maia Oncology, Turquoise Health, Count Me In and Getlabs. He serves as a board observer at Proximie. —🙏Thank you to our show sponsor, LookDeep. LookDeep pioneers AI that can see, hear, and respond with care to help hospitals be Ever Present for Every Patient. Learn more at lookdeep.ai/aimee.—📍 Connect with us:Heart of Healthcare websiteLinkedInInstagramTikTok If you're enjoying the show, would you please leave us a review? See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Some founders win support because of their product, others because of their story. In healthcare, where trust is everything, the ability to tell a compelling and authentic narrative can make or break a company.On this episode, Halle talks with longtime friend and colleague Christina Farr—reporter turned investor and now author of The Storyteller’s Advantage. Chrissy has spent thousands of hours hearing startup pitches, advising founders, and studying what makes certain stories resonate while others fall flat. She shares insights from her years as a journalist and investor, and lessons from her new book on how narrative power shapes companies and industries.We cover:📝 The three types of founder stories and why “personal experience” dominates in healthcare📉 Why failure stories are scarce in healthcare—and how that holds founders back🏆 The psychology of the underdog and how startups can use it to their advantage📰 The double-edged sword of media attention, especially for women leaders🎤 Why founder-led communications matter more than ever in an era of spammy PR pitchesAbout our guest:Christina Farr is an editor-in-chief of the health-tech newsletter Second Opinion, which has 40,000 subscribers. She advises startups as a national advisor with Manatt, and she's a GP with the fund Scrub Capital. Prior to that, she worked as an investor at OMERS Ventures and a journalist with CNBC, Fast Company, and Reuters News. Her debut book "The Storyteller's Advantage" is now available. She was born and raised in London, U.K., and resides in New York with her husband and two children. —If you're enjoying the show, we would so appreciate it if you left us a review!—📍 Connect with us:Heart of Healthcare websiteLinkedInInstagramTikTok See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Thanks to improved accuracy and new form factors, wearables have evolved from novelty step counters to tools that can predict illness, nudge healthier behaviors, and even influence alcohol consumption. But can they really bridge the gap between consumer wellness and enterprise healthcare?In this episode, ŌURA CEO Tom Hale discusses the lessons his team has learned from developing one of the most widely used health-tracking devices. We explore what draws people to wearables, what sustains their engagement, and how these tools may be shaping behavior and healthcare itself. We cover:🕰️ The past, present, and future of wearables🩺 What it takes to build trust with users, clinicians, and payers🍷 The number one thing people do differently after wearing an Oura ring🔑 Unlocking behavior change, and which habits are most malleable🏥 Why payers and health systems are beginning to integrate wearables into care models—About our guest:Tom Hale is the Chief Executive Officer at ŌURA and a member of its board. As the CEO he sets the company’s business strategy and vision to make health a daily practice for members all over the world. He has over 30 years of experience across the technology and consumer product industry.Before joining ŌURA, Hale was president of Momentive where he drove B2B strategy and led product growth. During his time there he was instrumental in taking the company public in 2018, leading the team in key acquisitions, and driving the evolution and rebranding of the company into a multiple SAAS business. Previously, he held leadership roles at HomeAway and Linden Lab as the Chief Operating Officer and Chief Product Officer, respectively, and held executive roles at Macromedia and Adobe.Hale has a Bachelor of Arts from Harvard University and sits on the boards of Cars.com, RocketReach, and NoiseAware.—If you're enjoying the show, we would so appreciate it if you left us a review!—📍 Connect with us:Heart of Healthcare websiteLinkedInInstagramTikTok See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

AI companies are hitting growth milestones in record time—some reaching $100 million in revenue in just two years. But while this pace feels familiar in tech, healthcare has always been slower to adopt new tools. That may finally be changing.Kent Bennett and Sofia Guerra of Bessemer Venture Partners join Steve Kraus to unpack findings from Bessemer’s State of AI 2025 report and what they mean for healthcare. From “supernovas” and “shooting stars” to the rise of systems of action, they explore how AI is reshaping not only software businesses but also the way doctors, health systems, and patients interact with technology.We cover:🚀 Why some AI companies are growing faster than the best SaaS businesses of the past decade🏥 How healthcare AI adoption is starting to catch up with other industries📊 The difference between systems of record and systems of action—and why it matters for doctors and patients🔎 Whether general-purpose models like ChatGPT will dominate healthcare search, or if specialized tools will win out⚖️ Why evals and data lineage may become make-or-break for safe AI deployment in healthcare—About our guests:Sofia Guerra is a vice president at Bessemer Venture Partners, where she invests in seed to growth healthcare and life sciences companies. She is the co-author of State of Health Tech report, Benchmarks for Growing Health Tech Business, and how to scale health tech businesses to $100M and beyond, a study of 100+ best-in-class companies to understand key metrics relevant for scalability in healthcare software and tech-enabled services.Sofia began her career as a consultant at Bain and Company, where she worked on strategy, operations, and due diligence projects across healthcare and technology.Prior to joining Bessemer, she was an investor at BoxGroup Ventures and the co-founder and co-president of Nucleate, a national life sciences entrepreneurship program helping PhDs, Post-docs, and students commercialize scientific projects.Sofia earned her MBA from Harvard Business School and her BA with high honors in Chemistry from Harvard University. While in school, she conducted research alongside Bob Langer, a serial entrepreneur and one of 12 Institute professors at MIT widely recognized for his contributions to drug delivery and tissue engineering fields.She was born and raised in Guatemala, went to boarding school in Singapore for the last few years of high school, and has traveled to over 35 countries. In her free time, she enjoys listening and dancing to reguetón and traveling to new places with her fiancé Alex.Kent Bennett is a partner in Bessemer’s Cambridge office focusing on B2B application software and consumer “earthquakes.”Before his career in venture capital, Kent was a creative executive for an entertainment production company, where he developed and sold original material including a network television pilot and a feature film. He began his career with Bain & Co., where he worked on projects in industries spanning IT, retail, consumer products, healthcare, and biotech.Kent earned an MBA from Harvard Business School, where he was a Baker Scholar, and graduated summa cum laude in systems engineering from the University of Virginia, where he was a Jefferson Scholar.—🙏Thank you to our show sponsor, LookDeep. LookDeep pioneers AI that can see, hear, and respond with care to help hospitals be Ever Present for Every Patient. Learn more at lookdeep.ai/aimee.—If you're enjoying the show, we would so appreciate it if you left us a review!—📍 Connect with us:Heart of Healthcare websiteLinkedInInstagramTikTok See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Healthcare’s “back-to-school” season delivered no shortage of big headlines! From Epic’s big leap into AI to a looming insurance “blood bath,” Steve and Michael break down the stories that shaped digital health this month.We cover:🖥 Epic’s 200 new AI “colleagues” and what it means for the battle between systems of record vs. systems of action💼 Why healthcare CEOs are cashing record paychecks despite shaky stock performance📉 The warning signs of soaring insurance premiums and their political fallout heading into 2026🤖 Hospitals turning to robots to fill critical workforce gaps⚖ The wild policy divide on how AI should (or shouldn’t) be allowed to practice medicine🎧 How an AI-powered stethoscope could change the way GPs catch heart disease—🙏Thank you to our show sponsor, LookDeep. LookDeep pioneers AI that can see, hear, and respond with care to help hospitals be Ever Present for Every Patient. Learn more at lookdeep.ai/aimee. —📍 Connect with us:Heart of Healthcare websiteLinkedInInstagramTikTok SubstackSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Healthcare costs keep climbing, and yet patients and employers often feel powerless to change the system. What if outsiders—those not steeped in the traditions of healthcare—are actually the ones best positioned to fix it?This special episode is a reshare from The Benefits Playbook podcast, where Halle joins Collective Health CEO Ali Diab. Together, they unpack what it takes to make health benefits simpler, more transparent, and more consumer-focused.We cover:🏥 The growing “consumer awakening” in healthcare and what it means for employers🧾 How Ali’s personal fight with insurance denials led to building a new kind of health company💡 Why outsiders can sometimes see solutions insiders overlook🤖 Where AI can actually improve care—and where human advocates are still indispensable💊 The GLP-1 dilemma for employers balancing access, equity, and costAbout our guest:Ali Diab is the CEO and Co-Founder of Collective Health, the World’s leading independent third-party health benefit plan administrator (TPA), integrating AI-powered health plan administration, health benefit plan member navigation and advocacy, and digital benefits hub.Ali has more than 25 years of experience leading high-growth technology organizations, and prior to co-founding Collective Health, was Vice President of Product Management and Business Operations at AdMob by Google. Previously, Ali held executive and management positions at Goldman Sachs, Microsoft, and Yahoo!. Ali is a graduate of Stanford and Oxford Universities and is a Member of the Board of Advisors of the Stanford Institute for Economic Policy Research (SIEPR).—🙏 If you're enjoying the show, we would so appreciate it if you left us a review!—📍 Connect with us:Heart of Healthcare websiteLinkedInInstagramTikTok See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Hospitals are under immense pressure: burned-out clinicians, outdated systems, and rising costs have made delivering care harder than ever. Tanay Tandon, founder and CEO of Commure, shares how his team is rethinking hospital infrastructure by combining AI, forward-deployed engineering, and a provider-first mindset. Backed by over $750M in funding, Commure is using strategic M&A and next-gen tools like ambient AI to reduce administrative burden, improve revenue cycle operations, and protect clinical staff.We cover:📉 How Commure grew claims volume 5x without hiring more staff🧠 Why the “copilot” era of AI may give way to true automation in back-office tasks🏥 Tanay’s prediction for a simpler, decentralized hospital system—powered by software💰 What it means to take capital from General Catalyst’s Health Assurance Fund and build for its customer network📰 How Commure navigated negative press around its business model and acquisitions—About our guest:Tanay Tandon is CEO at Commure, a $6B healthcare software company. The business uses LLMs to help supercharge the productivity of clinicians, healthcare administrators, and finance teams. Commure has raised over $500 million, is backed by Sequoia Capital, General Catalyst, Initialized, YCombinator, and NVIDIA. The company’s technology powers daily workflows for 250,000 providers at over 100 major health systems.—🙏 If you're enjoying the show, we would so appreciate it if you left us a review!—📍 Connect with us:Heart of Healthcare websiteLinkedInInstagramTikTok See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

One in four Americans is enrolled in Medicaid, yet the system designed to support them is constantly at risk—underfunded, politically vulnerable, and often overlooked.Dr. Alastair Bell, President and CEO of Boston Medical Center Health System, shares how his organization is reimagining what it means to care for underserved populations, while managing nearly 40% of Massachusetts’ Medicaid enrollees. In this conversation, we explore the financial realities of running an “essential” hospital system, the opportunities and pitfalls of Medicaid ACOs, and why AI might deepen inequity if essential providers are left behind.We cover: 🏥 What makes an “essential” hospital system (and why the term matters) 📊 How BMC manages risk across one of the largest Medicaid plans in New ⚖️ Why risk adjustment in Medicaid populations is still falling short 💊 What the 340B drug pricing program really means for safety-net hospitals 🧠 The promise (and peril) of AI in essential care settings—About our guest:Dr. Alastair Bell oversees the comprehensive system strategy and operations of BMCHS' entities, including BMC, Boston Accountable Care Organization, Clearway Health, and the WellSense Health Plan.Prior to joining in 2012, Dr. Bell was a leader in the North American payor and provider practice at McKinsey and Company, advising a range of national and international healthcare organizations and leading large-scale transformation programs. He received his Doctor of Medicine from the University of Oxford, his Master of Arts in physiology from the University of Cambridge, and his Master of Business Administration with distinction from Harvard Business School. Dr. Bell currently serves as co-chair of the board for the Boston Children’s Chorus.—🙏 If you're enjoying the show, we would so appreciate it if you left us a review!—📍 Connect with us:Heart of Healthcare websiteLinkedInInstagramTikTok See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Three simple questions plague every American seeking healthcare: Where should I go? When can I be seen? And how much will it cost me? Despite seeming basic, these questions have remained largely unanswerable—until now.In this episode, we explore how Heather Fernandez, co-founder and CEO of Solv, is building the infrastructure behind same-day care for 210 million Americans. We discuss how AI is finally cracking the code on price transparency and why workflow complexity can be a competitive moat in healthcare.We cover: 💰 Why price transparency has been so elusive and how AI tools are positioned to finally solve it 🤖 How AI is eliminating "garbage work" and turning front desk staff into healthcare superheroes ⚡ Why workflow expertise is a durable advantage for healthcare startups🚀 How to build a culture of AI at your startup💡 Why "intractable" problems may now be solvable—About our guest: Heather Fernandez is the CEO and co-founder of Solv Health, a leading platform redefining access to everyday healthcare. Solv connects consumers with a national network of providers, enabling same-day appointment availability and price transparency for patients across the country. For providers, the Solv platform acts as a growth copilot, leveraging AI to eliminate unnecessary administrative work, optimize existing capacity, and modernize the patient experience through our voice agent Maya and ClearPay price transparency. Solv integrates with EHR systems to streamline scheduling, intake, messaging, patient payments, and insights. To date, Solv has powered over 100 million visits nationwide with providers like Yale New Haven Health, GoHealth and ZoomCare.Heather has built her career around intuitive, transparent consumer experiences, previously helping scale Trulia through its acquisition by Zillow. She serves on Atlassian’s Board of Directors and is a graduate of UC Berkeley and Stanford GSB.—🙏 If you're enjoying the show, we would so appreciate it if you left us a review!—📍 Connect with us:Heart of Healthcare websiteLinkedInInstagramTikTok See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

A new federal law is reshaping how healthcare is paid for and delivered in America.In this episode, Steve sits down with health policy expert Joe Mercer to unpack the details of the One Big Beautiful Bill Act. It’s the most significant healthcare legislation since the ACA, with ripple effects across Medicaid, rural hospitals, and the ACA exchange.We cover: 🧾 What Medicaid work requirements could mean for coverage and churn 🏥 Why safety-net and rural hospitals are bracing for impact 💸 How changes to provider taxes and state-directed payments shift funding dynamics 📉 What happens when ACA subsidies start to expire 🧰 Where there may be operational opportunities for coverage tech and patient engagement solutions—About our guest:Joseph Mercer -  Managing Director, Marwood Group is a senior healthcare policy subject matter expert with Marwood and is the firm leader for healthcare services coverage out of Marwood's Washington DC Office. Additionally, Mr. Mercer operates as a firm leader across Marwood's DC-focused research coverage, policy diligence support and retainer practice offerings. Prior to joining Marwood in 2015, Mr. Mercer worked at the Centers for Medicare & Medicaid Services (CMS) serving as a Program Analyst at the Center for Consumer Information and Insurance Oversight (CCIIO). From his tenure at CMS, Mr. Mercer brings with him substantial expertise covering government health insurance programs with a focus on ACA exchange, Medicare Advantage and Medicaid policy issues and catalysts. Mr. Mercer holds a JD from Washington & Lee University School of Law and a BA in Economics from the College of William and Mary.—🙏 If you're enjoying the show, we would so appreciate it if you left us a review!—📍 Connect with us:Heart of Healthcare websiteLinkedInInstagramTikTok See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Fresh off a $243 million fundraise from Oak HC/FT and A16Z, Ambience Healthcare is on a mission to kill medical billing — and build “Iron Man suits for doctors.”Today we sit down with co-founder and CEO Mike Ng to talk about how Ambience is tackling one of healthcare’s most painful problems: the administrative burden that eats up 73% of a clinician’s day. We cover: 🏥 How Ambience tackles both clinical documentation and medical coding simultaneously (and why this dual approach was initially controversial with investors) 📊 The metrics he obsesses over to know if they’re succeeding🎯 Why specialty-specific AI models outperform general-purpose solutions in complex medical subspecialties 📈 Real-world results from Cleveland Clinic's five-way ambient listening comparison study—About our guest: Mike Ng is the co-founder and CEO of Ambience Healthcare, developing AI-powered clinical documentation platforms for healthcare providers. Before starting Ambience, Mike ran a care delivery organization, giving him firsthand insights into the challenges of healthcare operations, physician management, and the gap between software demos and real-world implementation. His experience spans both the operational and technological sides of healthcare, informing Ambience's approach to building AI solutions that work seamlessly within existing clinical workflows.—🙏 If you're enjoying the show, we would so appreciate it if you left us a review!—📍 Connect with us:Heart of Healthcare websiteLinkedInInstagramTikTok See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Dexcom generates more than $4 billion in annual revenue and has a market cap north of $30 billion, making it one of the biggest digital health companies in the world. And it all started with a better way to measure blood sugar.In this episode, Halle is joined by Kevin Sayer, CEO of Dexcom, the company that pioneered continuous glucose monitoring (CGM). Under Kevin’s leadership, Dexcom scaled from $40 million to $4 billion in revenue, became the standard of care for people with diabetes, and is now expanding into consumer wellness with its direct-to-consumer product, Stelo.We cover:📈 How Dexcom scaled 100x without relying on acquisitions📱 Why real-time glucose data is so powerful—and who needs it beyond diabetes🤝 Building trust with both doctors and patients⚖️ What GLP-1s mean for Dexcom’s business📦 The shift from regulated med device to consumer tech📊 The future of metabolic health (and what else their sensors might measure next)—About our guest:Kevin Sayer is the Chairman of the Board of Directors and Chief Executive Officer of Dexcom.Kevin assumed the role of CEO in January 2015 and became Chairman of the Board in July 2018. Kevin has also served as our President since 2011. He held the role of Chief Operating Officer from January 2013 until January 2015. Kevin has served as a member of Dexcom’s Board of Directors beginning in November 2007, prior to his role as Chairman and CEO.Prior to leading Dexcom, Kevin held various management positions in his prior roles. He served as Chief Financial Officer of Biosensors International Group, Ltd., Executive Vice President and Chief Financial Officer of Specialty Laboratories, Inc., Chief Financial Officer of MiniMed, Inc., and Vice President and General Manager of Medtronic MiniMed after the acquisition of MiniMed by Medtronic.Kevin is a Certified Public Accountant (inactive) and received a Bachelor’s degree and a Master's degree in Accounting and Information Systems from Brigham Young University.—🙏 If you're enjoying the show, we would so appreciate it if you left us a review!—📍 Connect with us:Heart of Healthcare websiteLinkedInInstagramTikTok See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

More than a thousand AI medical devices have FDA clearance, yet fewer than two percent of radiologists actually use them.In this episode, Steve sits down with Dr. Brian Anderson—CEO and co‑founder of the Coalition for Health AI—to unpack why trust, transparency, and regulation could make or break the next wave of AI‑powered medicine.We cover:🤖 Why only 2% of radiologists use AI tools despite 1,000+ FDA‑cleared devices🔍 What transparency really means and how model cards act like AI “nutrition labels”🏛️ How federal vs. state regulators could speed up—or stall—AI‑driven care💊 The imminent arrival of autonomous AI doctors that prescribe meds—and who’s liable when things go wrong🚑 Brian’s bullish vs. bearish scenarios for health AI over the next three yearsAbout our guest: Dr. Brian Anderson is President and CEO of the Coalition for Health AI (CHAI), leading the development of technical standards and best practices for MLOps in healthcare, including governance, evaluation, and monitoring in Health AI Assurance Labs. Previously, he was Chief Digital Health Physician at MITRE, where he led initiatives like Advancing Clinical Trials at the Point of Care (ACT@POC) and co-led MITRE’s largest oncology R&D effort supporting the Cancer Moonshot.A recognized expert in digital health and Health AI, Dr. Anderson has led work in clinical decision support, interoperability, and health IT standards. He formerly led the Informatics and Network Medicine Division at Athenahealth and has served on national health IT committees with the ONC. He earned his MD with honors from Harvard Medical School, a BA in Social Anthropology from Harvard College, trained at Massachusetts General Hospital, and practiced at Greater Lawrence Family Health Center. He lives in the Boston area with his wife and three children.—🙏 If you're enjoying the show, we would so appreciate it if you left us a review!—📍 Connect with us:Heart of Healthcare websiteLinkedInInstagramTikTok See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

When Andrew Lacy launched Prenuvo, the medical establishment largely dismissed it as fringe. Now, some of those same skeptics are collaborating with him on research.In this episode, Halle and Michael sit down with Andrew, founder and CEO of Prenuvo, to unpack what it takes to build trust in an unconventional idea. He opens up about how a moment of personal reckoning led him to pivot from tech to healthcare—and why he believes early detection should be a fundamental right.We cover:📊 How they’ve built the world’s largest dataset of whole-body MRI imaging, and what they’re doing with that data✨ What happens when Kim Kardashian shares about your company on social media, unprompted💡 Going from being dismissed by the medical establishment to forming major research partnerships🧠 What Prenuvo’s dataset is revealing about early disease markers, brain perfusion, and aging📈 The economics of prevention vs. treatment—and why large employers are on their minds—About our guest:Andrew Lacy is the CEO and founder of Prenuvo, the leading proactive whole-body MRI. With a mission to redefine healthcare through proactive screening, Prenuvo has become the forefront of preventive medicine. Since its inception, the company has conducted over 100,000 scans, alerting 2.5-5% of patients to life-threatening conditions, from aneurysms to lesions to tumors. This achievement solidifies Prenuvo as the largest private provider of whole-body MRI, pioneering a new standard in proactive healthcare.A seasoned entrepreneur, Lacy has a proven track record of transforming bold ideas into industry-defining ventures. He played a pivotal role in developing the iPhone apps ecosystem as co-founder of Tapulous, a mobile app company later acquired by the Walt Disney Company. Beyond his entrepreneurial pursuits, Lacy’s career spans high-impact roles in strategy, finance, and product development at global institutions, including McKinsey & Company and Disney.In addition to leading Prenuvo, Lacy is an active advisor and investor in a diverse range of startups, applying his entrepreneurial expertise to help the next generation of innovators. With a passion for leveraging technology to improve lives, Lacy is shaping a healthcare future that prioritizes early detection, prevention, and patient empowerment.Show Notes: This is not a sponsored show, but our guest has generously provided a discount code for listeners. Take $300 off your Prenuvo scan with our listener code: Prenuvo.com/HOH —🙏 Thanks to Flexpa for sponsoring this episode. Flexpa is refactoring healthcare. Connect to 300+ health plans through a single, secure integration to access patient-consented, identified claims data instantly.—📍 Connect with us:Heart of Healthcare websiteLinkedInInstagramTikTok See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In their first podcast since going public, Omada Health CEO Sean Duffy joins us to reflect on the journey to bend the curve of chronic disease.From walking away from the traditional PMPM model to staying grounded in clinical outcomes, Sean shares hard-earned lessons from over a decade of building Omada—from a startup in Rock Health’s Chinatown office to IPO. We cover:🔧 Killing PMPM before it killed them (and the business model shift that made Omada viable)🎯 Designing digital experiences around actual outcomes and not just engagement💡 What sets Digital Health 2.0 apart, and why the next wave of companies needs to focus on care delivery, not just navigation or access 📈 What going public taught Sean about readiness, discipline, and running a mission-driven business at scale—About our guest:Sean co-founded Omada in 2011 with the aim of merging medical trends and cutting edge technology to revolutionize health care of chronic disease as we know it. Today, he proudly serves as CEO and has been instrumental in steering Omada toward global recognition, such as being hailed a potential “medical triumph” by The New York Times, and one of Fast Company’s 50 most innovative companies in the world.  A longtime devotee of healthcare and technology, Sean also founded a largely automated lifestyle business around Excel Everest, the interactive Microsoft Excel training tool he created. He formerly covered healthcare innovation as writer and editor for Medgadget, a popular medical technology blog.As CEO of Omada, Sean cares deeply about honing the organization’s exceptional products, values-driven approach to healthcare, and the innovative ways in which primary care can continue to better humanity.More recently, Sean has been spending more and more of his free time learning how to build and fly first-person view drones.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Dare we say digital health is back? The IPOs are IPOing, and startups (at least the AI ones) are back raising mega rounds. In this month’s Digital Health Download, Halle and Steve break down the recent headlines, including a blockbuster funding cycle for AI tools, a dramatic breakup between Novo Nordisk and Hims, and why Oregon’s new law could shake up how startups structure clinical care.We cover:📈 What the return of IPOs signals for the second half of 2025🦄 New ways of building and funding healthcare unicorns💔 The fallout from Novo Nordisk's split with Hims over compounded GLP-1s⚖️ Are we trading faster innovation for a lower standard of evidence in cancer treatment?⚠️ Why Oregon’s new anti-private-equity law could be a warning sign for startups📚 Rethinking med school as AI reshapes the future of the profession—Show Notes:Rock Health Unicorn AnalysisBloomberg’s cancer drug pricing investigationNEJM on changes to medical educationOregon Senate Bill 951 SummaryNovo Nordisk terminates partnership with Hims over compounding concerns—🙏 If you're enjoying the show, please leave us a review!—📍 Connect with us:Heart of Healthcare websiteLinkedInInstagramTikTokSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What does one do after selling their company to Amazon for $1 billion? Start a new one, of course.In this episode, Halle sits down with TJ Parker, pharmacist, entrepreneur, and advocate for consumer-centric digital health. After co-founding PillPack and selling it to Amazon, TJ stayed on for four years helping build Amazon Pharmacy. Now, he’s back at it with General Medicine, a new company focused on making care as seamless as any other online transaction.We cover:🧾 Why pricing opacity and short-term incentives make care so frustrating📦 What TJ learned from building PillPack—and how the Amazon acquisition actually played out🏥 His vision for General Medicine, and why his second time around feels more like sport than survival📉 The wild ride of taking on PBMs (and winning) 🪄 The one change he’d make to fix healthcare’s misaligned incentives—About our guest:TJ Parker is a general partner with Matrix and is the co-founder and former CEO of PillPack. As CEO of PillPack, in just five years, TJ raised over $100M in financing, grew the company to more than a thousand employees, and successfully sold the business to Amazon for $1 billion in 2018. Today, TJ is focused on starting, investing in, and advising other healthcare and consumer focused businesses. Most recently, he founded and is the lead investor in General Medicine.—🙏 If you're enjoying the show, we would so appreciate it if you left us a review!—📍 Connect with us:Heart of Healthcare websiteLinkedInInstagramTikTok See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Most medical care is backed by varying types of evidence, yet we apply higher standards to digital health tools before they’re trusted, adopted, or reimbursed.In this special episode, guest host Lucia Savage is joined by Dr. Vindell Washington of Verily and Dr. Aaron Carroll of AcademyHealth for a candid conversation about the uneven standards we apply to digital versus traditional care. Together, they explore how we define evidence, whose voices shape that definition, and what it takes to build trust in an AI-powered healthcare future.We cover:🧪 Why much of traditional care isn’t based on randomized controlled trials🔍 What types of validation make digital tools trustworthy to patients, payers, and regulators👩‍⚕️ Whether generative AI should be evaluated like other medical devices📣 How to integrate patient perspectives into evaluating health tech📉 The risks of requiring more proof from digital tools than from “standard” care📊 Why transparency—not perfection—is key to building trust in innovation—About our guests:Lucia Savage is a nationally recognized expert in healthcare regulation, digital health, privacy, and AI. She is the Chief Privacy and Regulatory Officer at Omada Health, a virtual-first care provider that has served over one million people with evidence-based cardio-metabolic and physical therapy programs. Lucia also serves on the boards of AcademyHealth and Tidepool, and advises ClaimsHero, which uses AI to simplify healthcare claims appeals. She was previously Chief Privacy Officer at the Office of the National Coordinator for Health IT under the Obama Administration, and has testified before Congress on health data and digital care. Lucia was named one of Rock Health’s Top 50 in Digital Health in 2021 and is a contributing author to two bestselling books on digital medicine and health technology.Vindell Washington, MD, MS, is the Chief Clinical Officer and Head of Health Equity at Verily. Dr. Washington provides clinical leadership across Verily’s research and care solutions and currently leads the company’s Center of Excellence for Health Equity. Dr. Washington previously served as the CEO of Onduo, Verily’s care solution for chronic condition management. Prior to Verily, he was Chief Medical Officer and EVP at Blue Cross Blue Shield of Louisiana where he oversaw network operations and contracting, medical policy and quality, disease management, and pharmacy benefits. Dr. Washington also served as National Coordinator for Health Information Technology (ONC), where he provided high-level executive direction and leadership for ONC programs, operations, and policies. Dr. Washington also served in several capacities at Franciscan Missionaries of Our Lady Health System including, President of the Health System Medical Group, Chief Medical Information Officer, and as the leader of health system quality and information technology. He received his medical degree from the University of Virginia and his MS in healthcare management from the Harvard University School of Public Health.Dr. Aaron E. Carroll is President and CEO of AcademyHealth and a nationally recognized pediatrician, health services researcher, and science communicator. Formerly Chief Health Officer and Distinguished Professor of Pediatrics at Indiana University, his work has focused on pediatric health IT, decision analysis, and healthcare policy. He is the author of The Bad Food Bible, co-author of three books on medical myths, and a former contributor to The New York Times and The Atlantic. He also co-edits the health policy blog The Incidental Economist and hosts the YouTube channel and podcast Healthcare Triage, where he explains health research and policy to broad audiences. —🙏 If you're enjoying the show, we would so appreciate it if you left us a review!—📍 Connect with us:Heart of Healthcare websiteLinkedInInstagramTikTok See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Most AI in healthcare promises superintelligence—but what if that’s the wrong goal entirely?In this episode, Michael and Halle speak with Othman Laraki, co-founder and CEO of Color Health, to talk about why real-world care doesn’t need a perfect model—it needs a better system. Othman breaks down how Color evolved from a consumer genetics startup into a nationwide virtual cancer clinic, why most diagnostics businesses fail, and how AI can actually support clinicians without trying to replace them.We cover:🤖 Why chasing “healthcare superintelligence” misses the point🧠 How Color uses AI to speed up care and not take over decision-making🏥 Their pivot from genetic testing to full-scale clinical delivery📉 How they cut time to treatment in half and boosted screening by 70%🤝 Partnering with OpenAI, Memorial Sloan Kettering, and major employers—About our guest:Othman Laraki is CEO and co-founder of Color Health, a platform for healthcare delivery, providing the technology, infrastructure, and logistics required to distribute large-scale health initiatives to diverse populations. Color is changing the way patients access cancer care through a first-of-its-kind, vertically integrated, and fully owned Virtual Cancer Clinic. Powered by a 50-state oncologist-led team of cancer-focused clinical experts, Color provides proactive, evidence-based care that is accessible to anyone, anytime, and at every step of the cancer journey. Prior to Color, Othman was an early Product leader at Google, where he worked on performance infrastructure and client-side software, including the Google Chrome browser. After leaving Google, he co-founded MixerLabs, which was one of Twitter's first acquisitions. Othman holds degrees in computer science and management from Stanford University and the Massachusetts Institute of Technology. He is a long-time investor and advisor to leading companies such as Pinterest, AngelList, Coinbase, Slack, Instacart, Gitlab, and others.—🙏 Thanks to Flexpa for sponsoring this episode. Flexpa is refactoring healthcare. Connect to 300+ health plans through a single, secure integration to access patient-consented, identified claims data instantly.—🙏 If you're enjoying the show, we would so appreciate it if you left us a review!—📍 Connect with us:Heart of Healthcare websiteLinkedInInstagramTikTok See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Over half of Americans now live with at least one chronic condition, yet our healthcare system still revolves around episodic, reactionary care instead of continuous, coordinated support.We talk with Dr. Jaewon Ryu—former CEO of Geisinger and now CEO of Risant Health—about how integrated delivery systems are reshaping the way care is paid for and delivered. With decades of experience spanning medicine, law, government, and leadership at some of the most respected healthcare institutions, Dr. Ryu offers a rare inside look at what it takes to scale value-based care in a fragmented system.We cover:🏥 What an integrated delivery system actually looks like—from both the patient and provider perspective📉 Why two patients with the same condition often face very different outcomes based on their insurance💡 How value-based care can ease workforce shortages and improve access without cutting corners📈 What Risant Health is doing to help more systems scale value-based care without sacrificing local autonomy—About our guests:Dr. Jaewon Ryu, MD, JD, is the CEO of Risant Health, a nonprofit created by Kaiser Permanente to expand and scale value-based care across diverse, multi-payer, multi-provider health systems. Previously, he served as President and CEO of Geisinger, Risant Health’s inaugural member. With a mission to improve community health outcomes and healthcare affordability, Risant Health aims to bring the benefits of coordinated, value-based care to a broader national landscape.Dr. Ryu brings deep cross-sector experience, having held leadership roles at Humana, University of Illinois Hospital, Kaiser Permanente, and in federal government at CMS and the Department of Veterans Affairs. He began his career as a practicing corporate healthcare attorney. From 2018 to 2024, he served two terms on MedPAC, advising Congress on Medicare policy, and currently sits on the boards of NCQA, The Commonwealth Fund, and the KP Medical Foundation. Dr. Ryu earned his B.A. from Yale, and both his M.D. and J.D. from the University of Chicago, completing his emergency medicine residency at Harbor-UCLA.—🙏 If you're enjoying the show, we would so appreciate it if you left us a review!—📍 Connect with us:Heart of Healthcare websiteLinkedInInstagramTikTok See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.