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Health Longevity Secrets
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Health Longevity Secrets

Author: Robert Lufkin MD

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The health advice you're getting isn't working. Want to know what the experts actually do for themselves? 

Health Longevity Secrets reveals the real science behind longevity, metabolic health, fasting, and disease reversal—the protocols that researchers and physicians use in their own lives, not just what they tell patients. 

Robert Lufkin MD is a medical school professor, practicing physician, and New York Times bestselling author. After reversing his own chronic disease through lifestyle medicine, he's on a mission to share what actually works. 

Each episode features in-depth interviews with world-class scientists, doctors, and biohackers who share their personal health strategies—no sponsored talking points, just real answers. 

Your health transformation starts here.

249 Episodes
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Christine Trimpe was morbidly obese, pre-diabetic, and couldn't walk a half-mile mountain trail. Ten years later, she's lost over 100 pounds, reversed fatty liver disease and sleep apnea, and coaches thousands of women through metabolic healing - all by quitting sugar. In this episode, Christine shares her turning point moment on a Rocky Mountain trail, how discovering Dr. Jason Fung's work changed everything, why "everything in moderation" is the most dangerous dietary advice, and the surpr...
A high calcium score, a stack of prescriptions, and the nagging sense that “healthy eating” wasn’t working—David Etheridge’s story captures what millions feel but rarely decode. When he shifted from chasing calories to controlling insulin, everything changed: he moved from a 12:12 rhythm to a 16:8 fasting window, led meals with protein and natural fats, saved carbs for later on the plate, and watched both cravings and brain fog fade. The scale moved, but the labs told the real story—A1C from ...
What if the real lever for lasting weight loss isn’t calories, but hunger itself? We sit down with Dr. Jason Fung to unpack why willpower-based diets fail and how hormones like insulin, cortisol, GLP-1, and sympathetic tone quietly set your “fat thermostat.” Instead of fighting biology, we explore how to work with it—lowering insulin, raising satiety, and removing the triggers that keep appetite stuck in overdrive. We dig into the three types of hunger that shape daily choices: homeostatic (...
Think your brain has to slow down with age? We push back hard with science, stories, and a step-by-step plan that has helped patients regain clarity in weeks, not years. Our guest, Dr Majid Fotuhi, a Harvard- and Hopkins-trained neurologist who has treated thousands of patients, explains why common forgetfulness isn’t the same as cognitive decline and how simple daily choices can restore sharpness at any age. We break brain health down to four core levers: increase blood flow, reduce inflamm...
A tech founder’s health fell apart, and the fix didn’t come from a supplement stack or another glossy wellness trend. It started with a hard look at seed oils, blood sugar spikes, and the way ultra-processed “healthy” foods quietly inflame the body. That reckoning led Vinny Lingham to the carnivore community, to measurable drops in HS-CRP, and ultimately to making Animal, a documentary that challenges popular diet narratives and asks a simple question: what if controlling insulin and inflamma...
Pain that creeps in, brain fog that lingers, weight that resists every effort—what if the culprit isn’t “just getting older,” but inflammaging? We sit down with Dr. Shivani Gupta, author of The Inflammation Code, to connect ancient Ayurvedic wisdom with modern science and map out a practical plan for cooling chronic inflammation. Instead of chasing symptoms, we focus on the terrain: circadian rhythm, gut health, stress load, and daily rituals that nudge the body back into repair mode. Shivan...
What if the most powerful biohack is simply getting the morning sun in your eyes and letting your wearables prove it works? We explore Medicine 4.0 with Steven Stavrou DCM, a South African physician-biohacker who blends Chinese and functional medicine with hard data, showing how ancestral habits and modern metrics can drive prevention, performance, and genuine wellbeing. We start with incentives and shift them toward staying well, then build a plan from baseline labs, HRV, sleep, and body co...
Feeling “fine” is not a plan. We sit down with Dr Sandeep Palakodeti —an Ivy League–trained internist who left elite institutions—to unpack why so much of healthcare reacts to disease instead of building durable health, and how treating your body like your ultimate asset can change the arc of your life. We dig into the core four foundations (sleep, diet, exercise, relationships), the hidden risks behind “normal for your age” labs, and the personalized strategies that help you extend your prim...
What if the core of fatigue, brain fog, and “getting old” is really an oxygen problem? We sit down with Brad Pitzele to unpack how exercise with oxygen therapy (EWOT) and red and near-infrared light can reboot cellular energy, open microcirculation, and dial down inflammation in a way that’s fast, practical, and measurable. Brad's story moves from autoimmune arthritis and melanoma risk to a sustainable routine that restored clarity and stamina—without spending hours in a chamber or crushing w...
What if the most powerful health checkup you ever had happened at your kitchen table, not a clinic? We sit down with Dr. Natasha Milinkovic, a UK physician who moved from the front lines of vascular surgery and emergency medicine to the leading edge of preventive care, to explore how lab‑grade at‑home blood testing and intelligent coaching can change outcomes before a crisis hits. We start with the problem he saw repeatedly: people arriving late with preventable chronic disease. That urgency...
What if the most powerful “sugars” aren’t fuel at all, but messages your immune system has been waiting to hear? We sit down with Dr John Lewis, a former professor whose lab uncovered striking cognitive improvements in people with moderate to severe Alzheimer’s after 12 months on a formula built from aloe and rice bran polysaccharides. The science takes us beyond calories and cravings into complex carbohydrates as signaling molecules—shaping inflammation, immune balance, and possibly neuropla...
What if the root cause of our most devastating chronic diseases—from Alzheimer's and cardiovascular disease to diabetes and cancer—could be traced back to the same cellular structures? And what if these tiny organelles hold the key to understanding how we age and potentially extending our healthspan? Dr. Hemal Patel, Professor in the Department of Anesthesiology at UC San Diego School of Medicine, takes us on a fascinating journey into the world of mitochondria. Far from being mere "powerhou...
Unlock the secrets to a longer, healthier life with our special guest, Kevin Ellis, the Bone Coach. This episode dives deep into the critical importance of bone health, far beyond just keeping you upright. From blood cell production to immune system support and mineral storage, Kevin explains how your bones play a vital role in your overall well-being. Learn why early bone density scans (DEXA scans) are crucial and how conditions like osteoporosis and osteopenia can silently impact your life ...
What if you could see your inflammation—and your pace of aging—from your kitchen table? We sit down with Bob Messerschmidt, an optical engineer turned Apple platform architect who helped seed Apple Health and the Apple Watch, then left to build a simple at-home device that measures ESR, a century‑old inflammation marker with fresh relevance for longevity. We unpack why chronic inflammation drives heart disease, stroke, neurodegeneration, and metabolic dysfunction, and why a single, trackable...
What if everything you've been taught about nutrition is not just wrong, but actively harming your health? Cary Kelly's story might make you question your most basic assumptions about food and wellness. Cary grew up in a household religiously following conventional dietary guidelines—low-fat everything, margarine instead of butter, minimal red meat, and plenty of "heart-healthy" grains. Yet by his late 40s, his health was deteriorating rapidly. Chronic inflammation ravaged his body, extra we...
Holiday flights don’t have to flatten your energy or your immune system. Dr. Robert Lufkin breaks down what actually happens to your body at altitude—lower oxygen, desert-dry cabins, stalled circulation—and shares a clear plan to stay sharp before, during, and after you fly. Instead of white-knuckling through recycled air and jet lag, you’ll learn how to turn the cabin into a controllable environment and land clear, not crushed. We start with the physiology: why pressurization strains mitoch...
Cravings aren’t just about weak will; they’re biology doing exactly what billions of food dollars engineered them to do. We sit down with Sander Brus to unpack how sweetness hijacks reward circuits, why kids are showing up with adult metabolic diseases, and what happens when you flip the switch on sweet taste itself. Sander takes us from his diagnostics background into the heart of metabolic health, explaining how sweet taste receptors (T1R2/T1R3) live on the tongue and in the gut, where the...
Keto for Cancer?

Keto for Cancer?

2025-11-1148:24

What if the real action in cancer isn’t in the genome, but upstream in the mitochondria and the metabolic “terrain” that shapes every signal your cells send and receive? We sit down with Dr Nasha Winters to rethink cancer as an ecologic disease and explore how shifting the terrain can change outcomes without rejecting standard care. We dig into why ketones are more than fuel. Nasha explains how a therapeutic ketotic state—reached through fasting, carb restriction, or exogenous support—can lo...
Imagine your brain as a world-building engine that never shows you the thing-in-itself, only a model tuned for survival. Now imagine a molecule that doesn’t just bend that model but switches it to a fully formed, hyper-detailed reality populated by entities that seem to think, act, and sometimes deny you entry. That’s the claim at the heart of our conversation with computational neurobiologist and DMT researcher Andrew Gallimore, author of Death by Astonishment. We start by laying the ground...
A facelift without a telltale ear scar sounds like sci‑fi—until you hear how Dr. Mark Mani designed it. We sit down with the Beverly Hills surgeon, artist, and inventor to explore how endoscopic deep‑plane lifting repositions the face where gravity actually acts, delivering natural contour without the stigma of visible incisions. Mark traces the decade it took to refine the approach, publish the first academic description, and train surgeons worldwide, and he explains why subtle, anatomically...
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Comments (3)

Christina Mancini

unlike the Molecular Hydrogen Institute, this guy is so vague I think he's full of it.

Oct 23rd
Reply

محمد💊

معجزه ی نیتریک اکسید بر سلامت و بهبود زندگی ،واقعا ارزش گوش کردن داره .👍💊🩺

May 31st
Reply

محمد💊

هورمون ،دایت و متابولیسم ،و تاثیرشون روی لانجویتی و طول عمر 🩺💊😋

May 30th
Reply