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In Search of Insight
In Search of Insight
Author: Nootropics Depot
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Nootropics Depot leads the supplement industry through expertly formulated products, tested in our world-class lab. Learn about the creativity behind Nootropics Depot's products, and the history behind the botanicals that keep us healthy and well in Nootropics Depot's monthly podcast.
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Now is the perfect time to start a refreshed daily supplement routine, or reinvent your current stack. This podcast episode pairs the most popular new years resolutions with supplements that can help you achieve them! Emiel and Erika discuss the products that they use for staying fit, calm under stress, and thinking creatively throughout the year. In addition, they cover supplement stacks that will support a multitude of health and cognition goals. Tune in for a refreshing podcast episode, and how you can design the blueprint for your fittest year yet. Loose weight - Berbelean, CyathermGain Muscle - Eurycomax, Cistamax, CreatineDrink less - Alcohol Defense before drinkingSubstitutes: Relievex, Supercritical Coriander, Kava, Kanna, Magnolia Bark, Shoden, TauromagEat Healthier - Infinigreens after a meal, Saffron, ALAThe Specialist GoalsImprove Mood - Saffron, Black Ginger, Kanna, Cistamax, CognanceImprove Relaxation - Ecklonia cava, Supercritical coriander, Lemon Balm, Baikal SkullcapImprove Cognitive Function (memory, focus, motivation) - OmegaTAU, Erinamax, Sabroxy, 4 DMA 7,8 DHF, Cognance, Mushroom Magic Matcha BallerEnhance Social Capabilities - Saffron, Kanna, Isoliquiritigenin, Tribugen, Eurycomax, Supercritical corianderImprove Sleep - Tauromag, Sleep support, Supercritical coriander, Lucidimax, LucidisporeImprove Libido - Black ginger, Tribugen, EurycomaxIncrease Stress Resilience - Panamax, ShodenImprove Immune Function - Immune defense, Immuse, LucidimaxFitness/Weight focusedCistamax or Eurycomax: Mood, libido, strength Cyatherm: Mood, libido, weightloss, blood flow, cognitive functionSaffron: Mood, focus, appetite reductionInfinigreens: Appetite reduction, micronutrients and blood flowCognition FocusedOmegaTAU: Memory, focus, moodCognance: Memory, divergent thinking, moodPolygala tenuifolia: Neuroplasticity, focus, motivation and moodErinamax: Memory, focus and moodBecoming Calmer Under StressPanamax: Relaxation, stress, mood, cognitive functionShoden: Relaxation, stress, mood, fitnessRhodiola Rosea 3% salidroside: Energy, stress, cognitive function, fitnessInfini-B: Energy without jitters Building a Social MoodBlack ginger: Mood, libido, blood flow, confidenceSaffron: Enhanced mood and focusCognance: Enhanced mood and focusIsoliquiritigenin: Relaxation, mood
Creating a synergistic supplement stack is harder than you think - in this month’s podcast episode, Emiel and Erika discuss Nootropics Depot’s strategy for creating powerful and effective supplement stacks. Bioassaying is the first step to creating a stack that works for you. In simple terms, this means taking a product on its own for a few days in a row, to observe its effects on your mental and physical state. Once you’ve gotten familiar with a single ingredient, it's time to add the next product into the mix, which forms the basis of your stack. If this process sounds too time consuming for you, don’t sweat it! Nootropics Depot has created a catalogue of excellently formulated stack products (InfiniLyte, Sleep Support, Eurycomax to name a few) which combine botanical ingredients, vitamins and minerals to achieve the ideal balance in a single product. Tune into the podcast episode to learn about Nootropics Depot’s secrets of stacking, earned through years of trial, error, and experience!Shop Nootropics Depot's Top Sellers here: https://nootropicsdepot.com/top-sellers/
Creating a synergistic supplement stack is harder than you think - in this month’s podcast episode, Emiel and Erika discuss Nootropics Depot’s strategy for creating powerful and effective supplement stacks! Watch this sneak peak from the full podcast episode to learn about why stacking supplements is so complex, and the basic knowledge and techniques you need in order to start building your own stack. Curious to learn more about Nootropics Depot's stack formulation process, and how you can create more synergistic stacks for yourself? Tune into the podcast premiere on Tuesday March 3rd at 10:00 AM MST! https://youtu.be/0yK7E4YcIc0Shop Nootropics Depot's Top Sellers Here: https://nootropicsdepot.com/top-sellers/
Standardization | There's No Secret To Supplement QualityWhat makes one supplement truly consistent — delivering the same reliable results every single time?In this episode of In Search of Insight, Emiel and Erika unpack the importance of standardization in supplement formulation. From cultivation and extraction to testing and formulation, standardization is the science that ensures quality, potency, and predictable results — batch after batch, year after year.🌿 What You’ll Learn:- Why standardization is the foundation of Nootropics Depot’s quality process- How standardizing bioactives drives consistent benefits you can actually feel- The story behind one of the first standardized botanicals: Bacopa monnieri- A head-to-head comparison of Nootropics Depot’s Bacopa monnieri 24% Bacosides Extract vs. Cognance (10% Ebelin Lactone) — two very different experiences from the same plantEmiel and Erika reveal how Nootropics Depot’s analytical, evidence-based approach sets our products apart from the industry standard, and why “cold, scientific precision” is the real key to unlocking the full potential of natural ingredients.Join us for the premiere on Wednesday, February 4th at 10:00 AM MST — and bring your questions! Our team will be in the chat for a live Q&A during the first showing.🎧 Watch → Subscribe → Join the conversation#NootropicsDepot #InSearchofInsight #QualityIsEverything #TransparencyYouCanSee #nootropics #naturalsupplementsthatwork
Your Fittest Year Yet | Supplement Blueprint for 2026Now is the perfect time to start a refreshed daily supplement routine, or reinvent your current stack. This podcast episode pairs the most popular new years resolutions with supplements that can help you achieve them! Emiel and Erika discuss the products that they use for staying fit, calm under stress, and thinking creatively throughout the year. In addition, they cover supplement stacks that will support a multitude of health and cognition goals. Tune in for a refreshing podcast episode, and how you can design the blueprint for your fittest year yet. Loose weight - Berbelean, CyathermGain Muscle - Eurycomax, Cistamax, CreatineDrink less - Alcohol Defense before drinkingSubstitutes: Relievex, Supercritical Coriander, Kava, Kanna, Magnolia Bark, Shoden, TauromagEat Healthier - Infinigreens after a meal, Saffron, ALAThe Specialist GoalsImprove Mood - Saffron, Black Ginger, Kanna, Cistamax, CognanceImprove Relaxation - Ecklonia cava, Supercritical coriander, Lemon Balm, Baikal SkullcapImprove Cognitive Function (memory, focus, motivation) - OmegaTAU, Erinamax, Sabroxy, 4 DMA 7,8 DHF, Cognance, Mushroom Magic Matcha BallerEnhance Social Capabilities - Saffron, Kanna, Isoliquiritigenin, Tribugen, Eurycomax, Supercritical corianderImprove Sleep - Tauromag, Sleep support, Supercritical coriander, Lucidimax, LucidisporeImprove Libido - Black ginger, Tribugen, EurycomaxIncrease Stress Resilience - Panamax, ShodenImprove Immune Function - Immune defense, Immuse, LucidimaxFitness/Weight focusedCistamax or Eurycomax: Mood, libido, strength Cyatherm: Mood, libido, weightloss, blood flow, cognitive functionSaffron: Mood, focus, appetite reductionInfinigreens: Appetite reduction, micronutrients and blood flowCognition FocusedOmegaTAU: Memory, focus, moodCognance: Memory, divergent thinking, moodPolygala tenuifolia: Neuroplasticity, focus, motivation and moodErinamax: Memory, focus and moodBecoming Calmer Under StressPanamax: Relaxation, stress, mood, cognitive functionShoden: Relaxation, stress, mood, fitnessRhodiola Rosea 3% salidroside: Energy, stress, cognitive function, fitnessInfini-B: Energy without jitters Building a Social MoodBlack ginger: Mood, libido, blood flow, confidenceSaffron: Enhanced mood and focusCognance: Enhanced mood and focusIsoliquiritigenin: Relaxation, mood
Cyatherm | Fat Thermogenesis | Burn Baby, Burn!Cyatherm is Nootropics Depot’s new thermogenic fat-burning supplement stack! Tune into the new podcast episode to learn about the science behind Cyatherm, and how it can help you reach your weight loss and fitness goals. In this month’s episode, we get into the difference between white and brown fat, how our bodies store and burn fat as energy, and why heat is essential in the fat burning process. We also break down the ingredients in Cyatherm, and how the addition of Black Ginger and Ecklonia Cava balance the stimulating effects of Cyatherm to provide more fat-burning benefits, as well as a subtle mood boost.
50 Best Selling SupplementsThis month, Emiel and Erika round up Nootropics Depot’s 50 Best Selling Supplements from 2025! To celebrate our 50th episode of In Search of Insight, we rounded up the 50 most-loved supplements from the past year, and reminisce on our favorite episodes of In Search of Insight. Tune into the new podcast episode on Tuesday November 4th to celebrate 50 episodes of the podcast, and to learn about Nootropics Depot’s most loved supplements from the last year!
Lucidimax | The Quest for Peak Reishi PotencyLearn how Nootropics Depot maximized the benefits of Red Reishi mushroom in a new podcast episode on our bioactive-packed stack, Lucidimax!Red Reishi is the ultimate mushroom for relaxation, sleep, respiration, and inflammation benefits. However, not all Reishi on the market contains the bioactives it claims, so naturally, we decided to test Red Reishi products from other brands to see how ours stacked up. In this podcast, our science director Ellie joins us to share these test results, discuss our methods for identifying important bioactives in Red Reishi, and what we’ve learned about the mushroom industry through years of research and product development!
Peruvian Black Maca | Capturing the Magic of the Andes With ScienceMaca has been used as a food source and supplement for thousands of years, but has been steadily gaining popularity amongst fitness enthusiasts and biohackers in recent years. Emiel and Erika take a dose of Nootropics Depot’s new Peruvian Black Maca powder and discuss the mechanisms of action responsible for its calming, mood-lifting, and libido-enhancing effects. Because of Maca’s growing popularity, sourcing quality Maca is more important than ever! Nootropics Depot has combined high quality gelatinized Maca with our Maca extract (5% macamides) and horseradish root powder, which work synergistically to strengthen the calming benefits of Maca. Emiel discusses the neuroscience behind maca’s effects, including how it works on cannabinoid and TRPA receptors to produce subtle stimulation, as well as how the fibers and starches in maca aid in healthy digestion and satiation. Erika and Emiel mix the Peruvian Black Maca powder with Infinigreens into a daily drink taken after breakfast, which provides them with energy, focus, and genuine fullness for the first half of the day. Want to learn more about our optimized and improved Peruvian Black Maca powder? Tune into the podcast on Tuesday September 2nd at 10:00 AM MST.
The Ultimate Tongkat Ali StackIn this podcast episode, we discuss the role of testosterone in muscle building, why men and women can both benefit from Eurycomax, and the perceptible confidence boosting effects of a single dose of Eurycomax! Emiel and Erika break down the science behind our optimized Tongkat Ali stack and how the combination of Tongkat Ali extracts, Horny Goat weed, Mucuna Puriens, Boron and Iodine can help you reach your fitness goals. If you are serious about reaching your fitness goals with high quality natural supplements, tune into this podcast and learn about the game changing and laser-focused ingredients in the Eurycomax stack. Podcast Chapters0:00 Introduction6:00 Taking EurycoMAX9:35 What’s Causing the Benefits? Cold water ultrasonic extract17:09 What are the pros and cons of Tongkat Ali?26:00 Why A Single Dose is Enough!27:45 Dopamine, Testosterone30:33 Ingredient Round Up39:52 Checking in On Perceptible Effects45:32 Sex Binding Hormone Globulin - Free Testosterone46:00 Boron Increases Free Testosterone49:40 Iodine Balances the Stack - Thyroid Regulation56:56 Motivation Effects of Eurycomax1:06:29 Balancing Estrogen Synthesis - Tongkat Ali + Icariin1:10:44 Testosterone Benefits of Eurycomax1:14:13 Mucuna Puriens - Testosterone and Dopamine Benefits1:16:00 Icariin Balances Estrogen and Testosterone1:18:00 Dosages of the Eurycomax Stack Ingredients1:19:20 Tongkat Ali of the Highest Quality
The First Real Ecklonia Cava on the Market?
Time for a Big Change...Emiel and Erika take you on a journey through temperate regions in the northern hemisphere, exploring the nootropic, spiritual, culinary, and medicinal uses of Lion’s Mane mushroom through time! Tune into the podcast and learn more about:✔️ Monks in Japan that have been using Lion’s Mane for centuries✔️ Relaxing and neuroprotective benefits of fruiting body and mycelium extracts✔️ Erinamax, the first lab-test verified liquid culture mycelium to contain Erinacine A✔️ New Directions in Erinacine and Lion’s Mane researchPodcast Chapters0:00 Lion’s Mane Use in Japan, China, Northern Hemisphere6:32 Hericium Erinaceus - Comparing Erinaceus to other Species7:30 Hericium Corraloides11:00 Tasting Lion’s Mane Mushroom RAW12:20 Southwest Mushrooms19:00 The Premium Price of Lion’s Mane23:43 Saprophyte - how does a Lion’s Mane mushroom grow?26:55 Forest Farming29:33 Fruiting Body vs. Mycelium Lion’s Mane37:41 I’m Feeling Something! Perceptible benefits of RAW Lion’s Mane46:31 Want to add Lion’s Mane to your Daily life?49:50 Amsterdam’s Noordermarkt51:47 Mushroom Magic Coffee Latte53:07 Ancient Wisdom - Feeling Perceptible BenefitsFollow Us on Social Mediahttps://www.instagram.com/insearchofinsight/https://www.reddit.com/r/NootropicsDepot/
Jungle To The Lab | The Ethnobotanist Life w/ Kerry Hughes
"Ethnobotany is the study of the relationship between humans and plants." - Kerry Hughes
Meet Kerry Hughes, ethnobotanist and author, and an inspiring member of Nootropics Depot's scientific advisory board. Kerry joins the podcast to discuss her background and passions as an ethnobotanist, and to share practical tips for connecting with the healing power of plants in our everyday lives, through supplements, food, incense, and spending time in nature.
Chapters
0:00 Introducing Kerry Hughes, Ethnobotanist
1:17 What is an Ethnobotanist?
3:08 Taking Erinamax, Tiger Milk + Cognance from the ND Catalogue
4:21 Popping Pills - Ethnobotany style
5:55 Effectiveness of Quick-Dissolve Cognance vs. Cognizance capsules
10:14 The Lack of Bitter Compounds in Our Foods
12:18 Bitter Sensors in Our Digestive Tract
18:03 Madronho
20:41 Herbaviore - ??
23:30 Bitter Compounds Regulate Blood Sugar - GLP1 Agonism
25:35 Biodiversity - We Don’t Save What We Don’t Value
27:45 California - LA Fires, Climate Crisis, Land Management
28:13 Cattle Grass
31:38 Gulf of Mexico - Hating on Swamps
35:25 Rewilding
37:05 Effects of Erinamax and Cognance
38:15 Experiential Accounts of Supplements
44:50 Being Mindful of Safety with Extracts - Purity
46:17 The Dose is the Poison
51:25 What’s In Your Garden?
51:45 The Squarest Ethnobotanist You’ll Ever Meet
55:55 Biodiversity
58:40 Regenerative Certification
1:01:55 Natural Wineries
1:02:17 Wild Yeast in Geuze and Lambiek
1:03:42 Plants are Sentient Beings
1:05:15 A World without Opiates
1:07:25 Use of plants, music, nature
1:10:25 Connection - Essential for Human Health
At Nootropics Depot, we're committed to raising the standards of the supplement industry through rigorous lab testing and transparency. This month, we spoke with Greg Doucette, IFBB Pro bodybuilder and founder of HTLT supplements, about the Turkesterone controversy that raised significant concerns within the bodybuilding community in 2022.
Greg is known for his impressive YouTube following and bold personality - not to mention his physique. When Nootropics Depot tested Greg’s product, Turk Builder, and found it didn’t meet its claimed Turkesterone content, Greg chose to address the issue and take corrective action.
In this podcast, we share lab results from Turkesterone products across the market, including those from HTLT's Turk Builder Max. Join us as we discuss the importance of integrity and quality in the supplement industry and explore the science behind these findings.
This is an important step towards greater transparency—tune in to learn more!
Chapters
0:00 Introduction
3:22 Turkesterone - Nootropics Depot Starts Asking Questions
4:30 HTLT - Fails Turkesterone Testing, Scandal Insues
5:45 Nootropics Depot Wants To Help Companies Improve
6:39 Turkbuilder Was a Fraud?!
7:50 FINALLY Greg Feels Vindicated
9:28 HTLT Thought They Were Doing The Right Thing
12:22 HPLC - High Performance Liquid Chromatography
15:34 TurkMax and TurkBuilder are VERIFIED PURE
19:18 Companies are Buying Fake Turkesterone and Profiting
21:55 How Did Greg Discover Turkesterone? Greg Meets Marwan
25:50 Difference Between Chinese and Uzbek Turkesterone
28:00 Turk Allows You To Feel More Aggression and Train Harder
28:39 Reselling Turkbuilder - A Second Chance
30:24 Everyone Wants A Mechanism of Action?!
34:24 Ecdysterone vs. Turkesterone Ratio
38:10 Ensuring Product Quality - For the Meatheads
38:28 Turkesterone is a Product that Can Make You Better
43:00 Researchers Aren’t Always Transparent
44:30 Quoting Bad Studies - How To Prove Identity and Purity?
49:00 TurkBuilder Uses Turkesterone as a Quality Control Point
51:45 Comparing TurkBuilder, TurkMax, and Beta Ecdysterone ND
55:58 Suppliers Lying and Spiking Products
57:30 Do It Right TWICE
59:50 Expedition to Uzbekistan
1:03:27 Terroir within Supplements - Ingredients and The Elements
1:08:30 Tasting Compounds - Can You Eat Ajuca Turkistanica Raw?
1:09:55 - Other Ecdysterone Compounds
1:12:14 Thank You To HTLT Partners in Uzbekistan
1:18:55 Snake Oil - The Real Story
1:20:00 What’s your favorite exercise in the gym?
1:27:25 Mr. Happy Stack
1:33:50 Requiem For A Dream?
1:38:06 I Feel Vindicated
Identity Crisis | Adulteration In The Supplement Industry
In this new episode, Emiel u/Pretty-Chill and Erika welcome Ellie, Nootropics Depot’s new Science Director. Emiel, Ellie, and Erika discuss why it's essential to lab test supplements for identity and purity, and what this means for consumers.
There are way too many products on the market that don’t contain the ingredients they claim to, and this is a serious problem. In this podcast, you’ll learn about how identity testing works, why Nootropics Depot is so passionate about quality, and why Ellie is thrilled to be a part of our lab and marketing team at Nootropics Depot! Happy listening!
Chapters
00:00 Introduction
1:39 Benefits of Stacking Mushroom Magic Matcha & Cognance
12:00 Botanical Origin Story
17:13 Identity Testing - Watercress
27:00 HPLC Plates for Identity Testing
31:40 Testing for Erinacine A
36:00 Science Communication
50:46 Reference Standards for Erinacine A
RELIEVEX | A Vendetta Against Pain
This month’s podcast is all about pain - and our new pain management stack, Relievex!
Buy Relievex from Nootropics Depot
https://nootropicsdepot.com/relievex-capsules/
We at Nootropics Depot have a vendetta against pain, and Relievex is our secret weapon that provides physical and mental relief from pain. In this podcast, product specialist Emiel and podcast host Erika discuss the question “What is pain?” and what we can do to address it. Naturally, we discuss why taking Relievex is a great way to manage pain as needed, or on a daily basis.
Chapters
0:00 Introduction
1:05 Taking a Full Dose of Relievex - what are the benefits?
5:48 Why take Relievex? Inspiration behind the product
10:26 The difference between perception of pain vs. healing the source
16:04 Discussing the source of Pain (injury, inflammation, stress, lack of sleep)
20:08 Breaking Down the Ingredients of Relievex
22:49 Ingredients & Effects - Kava
26:41 Ingredients & Effects - Lemon Balm
27:54 Ingredients & Effects - Maca
33:32 Ingredients & Effects - Tetrahydromagnolol
35:25 Ingredients & Effects - Palmitoylethanolomide
38:05 Ingredients & Effects - Supercritical Boswelia
40:22 Ingredients & Effects - Ginger
NEW PRODUCTS! InfiniLyte & BerbeLean
Learn about Nootropics Depot's new fitness supplements, InfiniLYTE and BerbeLEAN in this video! Our product specialist Emiel and In Search of Insight podcast host Erika break down the benefits, ingredients, and inspiration behind our two newest supplements.
00:00 Introduction
00:27 InfiniLyte - Comprehensive Electrolyte
42:20 BerbeLean - Berberine Stack
Video Episode | BERBERINE | Live Leaner, Happier, Longer
This podcast episode is about Berberine, the most effective supplement for weight loss and body recomposition. In this new episode you’ll learn how Berberine supports glucose metabolism, gut health, and our daily energy levels!
Try Berberine from Nootropics Depot!
https://nootropicsdepot.com/berberine-hcl-silymarin-tablets/
https://nootropicsdepot.com/berberine-phytosome-capsules-550mg/
Chapters
0:00 Introduction - Berberine Helps Manage Glucose Metabolism
3:00 Glucose Metabolism
5:20 Visceral Adipose Tissue & Testosterone
7:20 Berberine + Silymarin versus Berbevis (Berberine Phytosome)
8:45 Dosing Berberine + Silymarin After a Light Lunch
10:30 Sigma 1 - Stimulation and Energy Benefits from Berberine
12:50 Dosing Berberine + Silymarin versus Berberine Phytosome
13:45 GLP1 and Hunger Satiety
18:26 How does GLP1 Work?
19:22 How Berberine Supports Healthy Bacteria - Akkermansia muciniphila
20:25 Bioavailability Concerns - Berberine Silymarin vs. Berberine Phytosome
32:25 Berberine and Curcumin as Biofilm Disruptors
37:49 Berberine & AMPK Activation
45:58 Why Berberine vs. C3G or Black Ginger?
53:11 Mind + Body Connection - Gut Health + Mood
56:02 AMPK Activation + Mood
58:45 Berberine’s Effects on Neurotransmitters
Video Episode | BLACK GINGER | Bigger, Harder, Happier
A new podcast episode from In Search of Insight is here! This podcast episode is about our new Black Ginger extract. Black Ginger is a game-changing supplement for burning fat, achieving your fitness goals, boosting libido and sexual performance, increasing motivation and lifting mood.
In this podcast, Product Specialist Emiel and podcast host Erika discuss the science behind Black Ginger’s fat-burning and libido-boosting qualities. We explain key mechanisms for Black Ginger’s benefits including thermogenesis, body recomposition, and the role of brown fat cells. We also explore the sexual function benefits of Black Ginger, namely its PDE5 inhibition which increases blood flow, which allows for better erections and arousal. Adding to these benefits, Black Ginger has a unique method of lifting our mood and motivation through it’s modulation of neurotransmitter release and processing.
Buy Black Ginger from Nootropics Depot
https://nootropicsdepot.com/black-ginger-extract-capsules/
Podcast Chapters
0:00 Introduction + Double Dose of Black Ginger
4:34 Black Ginger Benefits
5:00 Fitness + Endurance Benefits of Black Ginger
10:47 Fat Burning + Body Recomposition Benefits
19:21 Muscle Protein Synthesis Pathways
23:11 Sitruin 1 Activation
28:45 Summary of Fitness Benefits + Pathways
30:30 Sexual Function + Libido Benefits
31:59 PDE5 Inhibition
39:25 Neurotransmitter Release Process
43:42 Summary of Libido Benefits
49:12 Perceptible Benefits of Black Ginger
53:15 Stacking Black Ginger
Mr. Happy | The Next Generation
1:27 Longecity Forum - Early Nootropics Community
3:20 Foundations of Supplement Experimentation
7:50 Shifting Towards Minerals and Micronutrients
15:30 Origins of Nootropics Depot + Our Purity Standards
18:31 Vendors and Sourcing
26:30 Lion’s Mane, Reishi, Mushroom Research
28:20 Cultivating Lion’s Mane
35:50 Reishi + Immune Response
39:40 Joshua’s Immune System Research - Biofilms
51:05 Future of Accessible Research Studies
55:00 Citizen Scientists






Thanks so much you two, super useful conversation about uric acid and its function in the body and brain?! Also, helped me understand the process from ATP all the way down, I hadn't actually put that process together in my mind - awesome. Keep up the good work, looking forward to more!