Claim OwnershipDigital Health Talks - Changemakers Focused on Fixing Healthcare
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A weekly podcast featuring healthcare providers using technology to improve access to healthcare, patient experience, and clinical outcomes.
Healthcare Technology leaders address big questions like what technologies are worth investing in today and how will technology change the future of healthcare?
Hear how programs in telehealth, healthcare data analytics, cloud, 5G, artificial intelligence, machine learning, and social determinants of health are shaping the future of healthcare.
Hosted by the HealthIMPACT Live Team
Megan Antonelli, CEO, HealthIMPACT Live
Janae Sharp, Founder, The Sharp Index
Shahid Shah, Chair, HealthIMPACT Live, Publisher, Medigy
Healthcare Technology leaders address big questions like what technologies are worth investing in today and how will technology change the future of healthcare?
Hear how programs in telehealth, healthcare data analytics, cloud, 5G, artificial intelligence, machine learning, and social determinants of health are shaping the future of healthcare.
Hosted by the HealthIMPACT Live Team
Megan Antonelli, CEO, HealthIMPACT Live
Janae Sharp, Founder, The Sharp Index
Shahid Shah, Chair, HealthIMPACT Live, Publisher, Medigy
193 Episodes
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One week until ViVE 2026 in Los Angeles. Join Megan Antonelli, John Lynn, Shereese Maynard, and Janae Sharp as they preview what matters for the 9,000 healthcare technology executives heading to the premier digital health event.We're breaking down the sessions positioning real dollars: the $50 billion rural health fund, AI governance becoming board-level priority, cybersecurity shifting to enterprise risk, and interoperability moving from advantage to table stakes. Which technologies are moving from pilot to procurement? Which partnerships signal strategic shifts? What should CIOs, CMIOs, and CDIOs prioritize?Strategic insights that turn conference attendance into a competitive advantage. Your ViVE briefing starts here.John Lynn, Founder, Healthcare IT TodayShereese Maynard, MS, MBA, askshereese.techJanae Sharp, Founder, The Sharp IndexMegan Antonelli, Chief Executive Officer, HealthIMPACT
FHIR-Native by Design: Why Legacy System Conversions Can't Compete with Purpose-Built InteroperabilityAs healthcare systems race to meet 21st Century Cures Act mandates, a critical question emerges: retrofit or rebuild? Mike O'Neill, CEO of MedicaSoft, explains why FHIR-native architecture delivers fundamentally different interoperability outcomes than legacy systems with API layers bolted on. This conversation cuts through vendor marketing to examine the structural, semantic, and operational advantages of building healthcare IT from the ground up on HL7 FHIR standards.O'Neill draws on extensive experience leading P&L, engineering, and operations across healthcare IT startups and public companies to explain what "FHIR-native" actually means in practice—and why it matters for CIOs evaluating vendor claims. Learn how purpose-built FHIR architecture eliminates middleware complexity, reduces integration costs, and enables real-time clinical data exchange that retrofitted systems struggle to deliver.Technical and operational differences between FHIR-native systems and legacy platforms with FHIR APIsCost implications of middleware elimination versus ongoing translation layer maintenanceHow FHIR-native architecture impacts system performance, vendor lock-in, and future scalabilityRegulatory compliance advantages under 21st Century Cures Act requirementsMike O'Neill, CEO, MedicaSoftMegan Antonelli, Founder & CEO, HealthIMPACT Live
As AI systems increasingly influence clinical decisions—from risk stratification to treatment recommendations—healthcare leaders face a critical question: When can we safely rely on AI, and when must human judgment remain in the loop?Professor Vasant Dhar, NYU Stern professor, veteran AI researcher, and author of the newly released Thinking With Machines: The Brave New World of AI, joins Digital Health Talks to deliver what healthcare executives urgently need: a practical framework for evaluating AI reliability, recognizing model blind spots, and designing guardrails that actually work.With decades of experience bringing machine learning to high-stakes environments and over one million downloads of his Brave New World podcast, Professor Dhar offers rare clarity on the mounting tension between rapidly advancing AI capabilities and our ability to evaluate their trustworthiness. Healthcare CIOs, CMIOs, and technology leaders will walk away with actionable insights for governing AI deployment—not just soundbites.Vasant Dhar, Author, Thinking With Machines: The Brave New World of AIMegan Antonelli, Chief Executive Officer, HealthIMPACT
Healthcare administrative costs consume 25-30% of total spending, yet most AI investments focus on clinical applications rather than operational efficiency. Dr. Yan Chow of Automation Anywhere discusses proven AI use cases delivering measurable ROI today, from revenue cycle management and EOB processing to automated clinical documentation while exploring emerging conversational AI capabilities reshaping patient and provider interactions. As health systems face continued margin pressure, Chow examines where automation investments generate immediate returns versus longer-term strategic value. He addresses the “art of the possible” in administrative AI, implementation realities for enterprise deployments, and why the next wave of healthcare AI may be less about diagnosis and more about eliminating the administrative burden strangling clinical workflows.Yan Chow, MD, MBAGlobal Healthcare Leader, Automation AnywhereMegan Antonelli, Chief Executive Officer, HealthIMPACT Live
Nearly half of Americans would accept 24/7 AI monitoring of their facial expressions, voice patterns, and typing behaviors for early mental health intervention—a striking finding that challenges assumptions about privacy in behavioral healthcare. Andy Flanagan, CEO of Iris Telehealth, discusses groundbreaking consumer research revealing the complex relationship between AI acceptance and human oversight in mental health care. With 73% demanding humans make final emergency decisions, the data exposes a critical gap between consumer readiness, regulatory frameworks, and provider capabilities. Flanagan explores what this means for healthcare technology investment strategies as behavioral health AI moves from pilot to production.Andy Flanagan, CEO, Iris TelehealthMegan Antonelli, Chief Executive Officer, HealthIMPACT Live
Five Good Things with Janae Sharp and Megan Antonelli: A rapid-fire segment highlighting positive developments in digital health. Janae and Megan share insights on recent innovations, successful implementations, and emerging trends that are driving progress in healthcare technology.Learn about cutting-edge solutions improving patient outcomesDiscover how technology is enhancing healthcare accessibilityGain insight into successful digital health implementationsStay informed about positive industry trends shaping the future of careJanae Sharp, Founder, The Sharp IndexMegan Antonelli, Chief Executive Officer, HealthIMPACT Live
Join us for an exclusive evening of networking and insights at the HLTH 2025 Provider Think Tank, hosted by HFMA SoCal on October 6th in Las Vegas. This intimate gathering brings together healthcare executives and industry leaders to explore the latest innovations in revenue cycle management, digital health transformation, and clinical operations. Connect with peers, share best practices, and gain actionable strategies to navigate the evolving healthcare landscape—all while enjoying cocktails and conversation in a relaxed, executive setting. Space is limited to ensure meaningful dialogue and relationship building.Monica Cepak, CEO, WispMegan Antonelli, Chief Executive Officer, HealthIMPACT Live
As Delaware implements the nation's first insurance mandate for early allergen introduction on January 1st, 2026, Meenal Lele, Founder & CEO of Lil Mixins and author of The Baby and the Biome, shares her journey from food allergy parent to medical entrepreneur. With multiple patents, published clinical studies, and an engineering background, Meenal built Hanimune Therapeutics to address a crisis affecting 33 million Americans. She discusses the clinical evidence behind early allergen introduction, navigating insurance coverage, and why state-level policy changes matter for reducing childhood allergies while saving healthcare systems millions. Discover how maternal insight combined with scientific rigor is transforming prevention.Meenal Lele, Founder & CEO, Lil MixinsMegan Antonelli, Chief Executive Officer, HealthIMPACT Live
Join us as Dr. Andrew M. Davis and Amy Wainwright from University of Chicago Medicine reveals how AI-powered analysis of 37,000+ patients exposed a crisis hiding in plain sight: nearly 30% of hypertensive patients have dangerously uncontrolled blood pressure despite regular primary care visits.Using cloud-based machine learning across 112 providers, Dr. Davis's team identified critical gaps traditional metrics miss—underutilized medications, missed referrals, and troubling disparities in care. More importantly, they developed interventions that work.Discover how to leverage advanced analytics for measurable ROI, implement real-time clinical intelligence at scale, and empower providers with data-driven feedback that reduces cardiovascular risk at the point of care.Andrew M. Davis, MD, MPH, Professor and Associate Vice-Chair for Quality, University of ChicagoAmy Wainwright, PharmD, Clinical Pharmacist, UChicago MedicineMegan Antonelli, Chief Executive Officer, HealthIMPACT Live
Join us as we explore a critical question: What if the solution to America's number one killer isn't in the pharmacy, but in the kitchen? Today's guest is Dr. Elizabeth Klodas, a Mayo Clinic and Johns Hopkins-trained cardiologist who founded Step One Foods after realizing that doctors, including herself, weren't addressing the most powerful intervention for heart disease diet.Elizabeth Klodas, MD, Founder & Chief Medical Officer, Step One FoodsMegan Antonelli, Chief Executive Officer, HealthIMPACT Live
Join us as we meet Margo Jordan, founder and CEO of Enrichly, who's flipping the script on childhood mental health. Instead of treating symptoms, she's building self-esteem from the inside out—reaching over 200,000 students through a gamified platform that kids actually want to use. From brick-and-mortar learning centers to a digital therapeutic that's now partnering with major health systems, Margo shares why self-esteem is the missing piece in mental health care, how she's hiding vegetables in the candy, and what it takes to bridge the pediatric behavioral health gap when 70% of US counties don't have a single child therapist. This is healthcare innovation that's both clinically sound and genuinely fun.Margo Jordan, Founder & CEO, EnrichlyMegan Antonelli, Chief Executive Officer, HealthIMPACT Live
Joining us is Kristen Miller, Co-Director of MedStar Health's Center for Diagnostic Systems Safety and Scientific Director of their National Center for Human Factors in Healthcare. As healthcare organizations invest billions in AI technologies, Kristen's research reveals that human factors engineering - the science of how humans interact with complex systems - determines whether AI becomes a safety enhancer or safety hazard, whether patients embrace or resist these tools, and whether healthcare teams achieve promised efficiencies or face new workflow disruptions.Kristen Miller, Scientific Director, MedStar Health National Center for Human Factors in HealthcareMegan Antonelli, Chief Executive Officer, HealthIMPACT Live
Join us for Five Good Things with Janae Sharp and Megan Antonelli: A rapid-fire segment highlighting positive developments in digital health. Janae and Megan share insights on recent innovations, successful implementations, and emerging trends that are driving progress in healthcare technology.Janae Sharp, Founder & CEO, The Sharp IndexMegan Antonelli, Founder & CEO, HealthIMPACT Live
Join us for a critical discussion on healthcare's most pressing cybersecurity challenge with Nikki Bennett, Healthcare Advisory Identity Strategist at SailPoint. Drawing from five years of frontline IAM experience at ECU Health, Nikki reveals how to transform identity vulnerabilities into strategic advantages, tackling everything from non-human identities and AI agents to cloud migration strategies. She shares breakthrough announcements from SailPoint's Navigate event and delivers actionable insights on why intelligent identity frameworks are becoming the cornerstone of healthcare's cybersecurity future.Nicki Bennett, Advisory Strategist, Healthcare, SailPointMegan Antonelli, Chief Executive Officer, HealthIMPACT Live
Join us for an in-depth conversation with Dr. Ryan Sadeghian, System CMIO at University of Toledo Health, as he shares his unique journey from healthcare consultant to practicing pediatrician to AI implementation leader. In this episode, we explore how academic health systems are uniquely positioned to drive healthcare AI innovation, balancing the dual mission of education and patient care while building practical AI solutions that solve real workflow challenges. Dr. Sadeghian discusses his organization's approach to developing internal AI capabilities, managing vendor relationships, and creating sustainable change management strategies that ensure successful AI adoption across clinical and administrative teams.Ryan Sadeghian, MD, MBA, MSc, System CMIO, University of Toledo HealthJanae Sharp, Founder, The Sharp Index
Join Megan Antonelli and Dr. Tom Kelly, co-founder of Heidi Health, as he brings a unique perspective to healthcare AI. He's a vascular surgery trainee turned founder who experienced firsthand the crushing administrative burden that keeps clinicians from truly connecting with their patients. With Heidi Health now serving over 500,000 clinicians and processing more than 2 million patient visits per week, Tom shares the fascinating journey from frustrated doctor to AI innovator. We dive deep into the reality versus the hype of ambient AI adoption, why clinician-first design trumps seamless integration, and the critical difference between tools that doctors tolerate and tools they actually love. From the nuances of personalization at the sentence level to envisioning an AI care partner that handles follow-ups and coordinates care, this conversation reveals what it truly takes to build healthcare technology that makes medicine more human—not less.Dr. Thomas Kelly, Co-founder & CEO, Heidi HealthMegan Antonelli, Chief Executive Officer, HealthIMPACT Live
Join Megan Antonelli as she speaks with Jenice Larmond, RN, BSN, MBA, Clinical Innovation & Excellence Officer at Neteera, about how radar-based ambient monitoring is rewiring clinical culture toward prevention. Discover how FDA-cleared contactless technology continuously monitors heart rate, respiration, and occupancy & motion insights through clothing and bedding—detecting subtle changes before they become crises. Learn why health systems report dramatic reductions in alert fatigue, increased early interventions, and prevention-focused care delivery. If you're building RPM, post-acute care, or aging-in-place programs centered on early detection, this conversation reveals the cultural shift happening now.Jenice Larmond, Clinical Innovation & Excellence Officer, NeteeraMegan Antonelli, Chief Executive Officer, HealthIMPACT Live
Join us for a conversation with Dr. Ashley Beecy, Chief AI Officer at Sutter Health, as she shares their journey from targeted AI pilots to enterprise-wide transformation across one of California's largest integrated health systems. We'll explore Sutter's innovative diabetic retinopathy screening program, where AI-enabled cameras deployed across 28 primary care sites detect sight-threatening conditions in under a minute, and their strategic partnership with Aidoc as the premier West Coast hub for clinical AI innovation. Dr. Beecy brings unique insights from her journey as a cardiologist and former AI leader at NewYork-Presbyterian. Clinical Leadership Drives AI Success: Dr. Beecy's background as a practicing cardiologist provides essential clinical credibility for enterprise AI transformation. Pilot to Platform Strategy: Focused pilots with clear clinical value can scale enterprise-wide when supported by proper governance and infrastructure. Real-World Impact at Scale: 24 cases of retinopathy detected from 216 screenings demonstrates measurable clinical outcomes from AI deployment. Strategic Partnerships Accelerate Innovation: Sutter's role as Aidoc's West Coast hub shows how health systems can co-develop AI solutions. Infrastructure Investment is Critical: Scaling AI across 24 hospitals and 200+ care sites requires robust governance frameworks and organizational commitment. Ashley Beecy, MD, FACC, Chief AI Officer, Sutter HealthMegan Antonelli, Chief Executive Officer, HealthIMPACT Live
Join us for an insightful conversation about the intersection of technology and healthcare with Pallavi Ranade from Intermountain Health and Janae Sharp. In this episode, we explore how healthcare organizations can effectively measure return on investment while keeping patient-centered outcomes at the forefront. From the hidden costs of technology implementation to the promise of AI and genomics, our guests share practical wisdom on navigating innovation challenges, allocating resources strategically, and ensuring that technological advances truly benefit both patients and clinicians. Whether you're a healthcare leader weighing your next tech investment or simply curious about the future of healthcare delivery, this discussion offers valuable perspectives on making technology work for everyone in the healthcare ecosystem.Pallavi Ranade-Kharkar, PhD, MS, FAMIA, Director of Research Informatics Genomics, Intermountain HealthJanae Sharp, Founder, The Sharp Index
Healthcare cybersecurity stands at an inflection point. Traditional compliance frameworks are proving inadequate in the face of sophisticated threats targeting patient data, clinical operations, and connected medical devices. Robert Eikel, CISO at P-n-T Data Corp., brings unique expertise from government service, financial services, and pediatric healthcare to discuss how leading organizations are evolving beyond checklist security. We'll explore the new frontlines of healthcare cyber defense—identity, integrity, and interoperability—while examining how emerging technologies like AI and quantum computing are reshaping the threat landscape.Moving from periodic compliance to continuous confidence through identity-centric, integrity-focused defense strategiesProtecting clinical workflows and patient safety while maintaining secure interoperability across healthcare ecosystemsPreparing cybersecurity programs for AI-powered threats, quantum risks, and next-generation healthcare technologiesTransforming cybersecurity governance from IT overhead to strategic business enablerRobert Eikel, Chief Information Security Officer, P-n-T Data Corp.Megan Antonelli, Founder & CEO, HealthIMPACT Live
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