Pri-Med Podcasts

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-452 Overview: The healthcare landscape is undergoing a sea change, significantly impacting established, evidence-based recommendations. Media coverage suggests that the HHS Secretary plans to release a report linking acetaminophen use during pregnancy with an increased risk of autism spectrum disorder (ASD) in offspring as well as linking maternal folate deficiency with ASD—associations that have not been supported by evidence. If promoted by public health agencies, such discrepancies pose a dilemma for clinicians who have relied on and trusted that guidance reflects evidence and is grounded in scientific methods. Join us to review the evidence on acetaminophen and ASD risk and learn strategies to ensure your practice is based on valid findings. Episode resource links: Ahlqvist VH, Sjöqvist H, Dalman C, et al. Acetaminophen Use During Pregnancy and Children’s Risk of Autism, ADHD, and Intellectual Disability. JAMA. 2024;331(14):1205–1214. doi:10.1001/jama.2024.3172   Damkier, P., Gram, E. B., Ceulemans, M., Panchaud, A., Cleary, B., Chambers, C., Weber-Schoendorfer, C., Kennedy, D., Hodson, K., Grant, K. S., Diav-Citrin, O., Običan, S. G., Shechtman, S., & Alwan, S. (2025). Acetaminophen in Pregnancy and Attention-Deficit and Hyperactivity Disorder and Autism Spectrum Disorder. Obstetrics and gynecology, 145(2), 168–176. https://doi.org/10.1097/AOG.0000000000005802   Ji Y, Azuine RE, Zhang Y, et al. Association of Cord Plasma Biomarkers of In Utero Acetaminophen Exposure With Risk of Attention-Deficit/Hyperactivity Disorder and Autism Spectrum Disorder in Childhood. JAMA Psychiatry. 2020;77(2):180–189. doi:10.1001/jamapsychiatry.2019.3259   Hirota T, King BH.  Autism Spectrum Disorder: A Review. JAMA. 2023;329(2):157–168. doi:10.1001/jama.2022.23661   Liu, X., Zou, M., Sun, C., Wu, L., & Chen, W. X. (2022). Prenatal Folic Acid Supplements and Offspring's Autism Spectrum Disorder: A Meta-analysis and Meta-regression. Journal of autism and developmental disorders, 52(2), 522–539. https://doi.org/10.1007/s10803-021-04951-8   DSM-5-TR: Neurocognitive Disorders Supplement; October 2022. https://psychiatryonline.org/pb-assets/dsm/update/DSM-5-TR_Neurocognitive-Disorders-Supplement_2022_APA_Publishing.pdf https://www.npr.org/sections/shots-health-news/2025/09/06/nx-s1-5532143/hhs-responds-to-report-about-autism-and-acetaminophen Guest: Susan Feeney, DNP, FNP-BC, NP-C   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com   

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-451 Overview: The obesity epidemic has fueled a demand for weight loss medications. Trials have directly compared medications—specifically glucagon-like peptide-1 receptor agonists (GLP-1 RAs)—with a recent study doing just that. Tune in as we explore the evidence comparing semaglutide and tirzepatide for weight loss outcomes up to 1 year. Episode resource links: Rodriguez PJ, Goodwin Cartwright BM, Gratzl S, et al. Semaglutide vs Tirzepatide for Weight Loss in Adults With Overweight or Obesity. JAMA Intern Med. 2024;184(9):1056-1064.  Moiz A, Filion KB, Toutounchi H, et al. Efficacy and Safety of Glucagon-Like Peptide-1 Receptor Agonists for Weight Loss Among Adults Without Diabetes : A Systematic Review of Randomized Controlled Trials. Ann Intern Med. 2025;178(2):199-217.  Wen J, Syed B, Nadora D, et al. Tirzepatide Versus Semaglutide on Weight Loss in Type 2 Diabetes Patients: A Systematic Review and Meta-Analysis of Direct Comparative Studies. Endocrinol Diabetes Metab. 2025;8(3):e70045.  Guest: Alan M. Ehrlich, MD, FAAFP Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-450 Overview: Use of e-cigarettes has increased significantly over the last several years and their popularity continues to grow, notably among adolescents and young adults. Recent evidence indicates that the majority of teens and young adults who vape consider quitting; however, nicotine addiction has historically been difficult to treat in this population. Join us as we discuss the prevalence of vaping, associated harms, and new evidence on the effectiveness of varenicline on cessation.  Episode resource links: CDC https://www.cdc.gov/tobacco/e-cigarettes/youth.html Evins, A. E., Cather, C., Reeder, H. T., Evohr, B., Potter, K., Pachas, G. N., Gray, K. M., Levy, S., Rigotti, N. A., Iroegbulem, V., Dufour, J., Casottana, K., Costello, M. A., Gilman, J. M., & Schuster, R. M. (2025). Varenicline for Youth Nicotine Vaping Cessation: A Randomized Clinical Trial. JAMA, e253810. Advance online publication. https://doi.org/10.1001/jama.2025.3810 Lindson N, Butler AR, McRobbie H, et al. Electronic cigarettes for smoking cessation. Cochrane Database Syst Rev. 2024;1(1):CD010216. Published 2024 Jan 8. doi:10.1002/14651858.CD010216.pub8 Park-Lee E, Ren C, Sawdey MD, et al. Notes from the Field: E-Cigarette Use Among Middle and High School Students — National Youth Tobacco Survey, United States, 2021. MMWR Morb Mortal Wkly Rep 2021;70:1387–1389. DOI: http://dx.doi.org/10.15585/mmwr.mm7039a4external icon;  Tuisku A, Rahkola M, Nieminen P, Toljamo T. Electronic Cigarettes vs Varenicline for Smoking Cessation in Adults: A Randomized Clinical Trial. JAMA Intern Med. 2024;184(8):915–921. doi:10.1001/jamainternmed.2024.1822 Zhang, L., Gentzke, A., Trivers, K. F., & VanFrank, B. (2022). Tobacco Cessation Behaviors Among U.S. Middle and High School Students, 2020. The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 70(1), 147–154. https://doi.org/10.1016/j.jadohealth.2021.07.011 Guest: Susan Feeney, DNP, FNP-BC, NP-C Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-449 Overview: In this episode, we discuss new evidence linking high compliance with the Dietary Approaches to Stop Hypertension (DASH) diet to lower risks of colorectal cancer, reinforcing the DASH diet’s well-established role in managing hypertension while also highlighting its potential to reduce cancer risk. Gain practical insights into translating these findings into actionable nutrition guidance to support your patients’ overall health. Episode resource links: Explain the risk factors for development of colorectal cancers Review the Dietary Approaches to Stop Hypertension (DASH) and discuss the proposed mechanisms for colorectal cancer reduction by following this approach Apply evidence from a meta-analysis to support dietary counseling strategies aimed at cancer prevention in clinical settings Guest: Jillian Joseph, MPAS, PA-C   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-448 Overview: Join us to discover how flavan-3-ols, found in tea, cocoa, and select fruits, can support cardiovascular prevention. Learn how to translate emerging evidence on blood pressure and vascular health into practical dietary guidance that empowers your patients and complements standard hypertension care. Episode resource links: European Journal of Preventive Cardiology (2025) 00, 1–13. https://doi.org/10.1093/eurjpc/zwaf173 Guest: Robert A. Baldor MD, FAAFP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-447 Overview: New data show that quitting smoking—even at age 65 or 75—can still add years to life. In this episode, we review the latest evidence on life expectancy gains and equip you with effective, evidence-based tools to support tobacco cessation and motivate patients at any age. Episode resource links: Le,Thuy TT., Mendez, D. , & Warner, K. (2024). The Benefits of Quitting Smoking at Different Ages. American Journal of Preventive Medicine, 67 (5), 684-688. https://doi.org/10.1016/j.amepre.2024.06.020.    What are the treatments for tobacco dependence? National Institute on Drug Abuse https://nida.nih.gov/publications/research-reports/tobacco-nicotine-e-cigarettes/what-are-treatments-tobacco-dependence Smokefree.gov offers Apps, counseling, texting support, tools and tips for your patient to build your quit plan Selby, P., & Zawertailo, L. (2022). Tobacco Addiction. The New England journal of medicine, 387(4), 345–354. https://doi.org/10.1056/NEJMcp2032393 Guest: Jill M. Terrien PhD, ANP-BC  Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-446 Overview: Overwhelmed by in-basket tasks? Discover a practical scheduling intervention that gives you time during the clinic day to manage portal messages. Learn how “portal practice slots” can reduce burnout, improve workflow, and empower you to advocate for changes that support sustainable, high-quality primary care. Episode resource links: J Gen Intern Med. DOI: 10.1007/s11606-025-09582-8 Guest: Robert A. Baldor MD, FAAFP Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-445 Overview: Managing knee osteoarthritis (OA) in patients with obesity can be challenging, especially when standard treatments fall short. In this episode, we discuss emerging evidence on the use of metformin to reduce knee pain in patients without diabetes and explore how this option could expand your approach to OA management. Episode resource links: Pan F, Wang Y, Lim YZ, et al. Metformin for Knee Osteoarthritis in Patients With Overweight or Obesity: A Randomized Clinical Trial. JAMA. 2025;333(20):1804-1812.  Guest: Alan M. Ehrlich, MD, FAAFP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com   

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-444 Overview: An estimated 30% of women worldwide are affected by bacterial vaginosis (BV), and although treatment is typically successful, recurrence rates remain high. Traditional strategies, such as treating male partners, have not significantly reduced recurrence. In this episode, we discuss a recent study that used a new approach to partner treatment and review its potential to reduce BV recurrence. Episode resource links: Vodstrcil LA, Plummer EL, Fairley CK, et al. Male-partner treatment to prevent bacterial vaginosis.  The New England Journal of Medicine. 2025; 392 (10): 947-957. doi: 10.1056/NEJMoa2405404. DynaMed: https://www-dynamed-com.umassmed.idm.oclc.org/condition/bacterial-vaginosis-bv#GUID-E1A22CF7-D0AC-4247-B1F8-54D1CD26FC1A Guest: Susan Feeney, DNP, FNP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com   

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-443 Overview: In this episode, we evaluate the correlation between an increase in physical activity and step count and a reduction in cancer risk. We break down new evidence, equipping you with practical guidance for counseling patients on simple, impactful behavior changes to support long-term health. Episode resource links: Shreves AH, Small SR, Walmsley R, et al. Amount and intensity of daily total physical activity, step count and risk of incident cancer in the UK Biobank. Br J Sports Med. Published online 2025. doi:10.1136/bjsports-2024-109360 Islami, F., Goding Sauer, A., Miller, K.D., Siegel, R.L., Fedewa, S.A., Jacobs, E.J., McCullough, M.L., Patel, A.V., Ma, J., Soerjomataram, I., Flanders, W.D., Brawley, O.W., Gapstur, S.M. and Jemal, A. (2018), Proportion and number of cancer cases and deaths attributable to potentially modifiable risk factors in the United States. CA: A Cancer Journal for Clinicians, 68: 31-54. https://doi.org/10.3322/caac.21440 Guest: Jillian Joseph, PA-C   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com   

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-442 Overview: Listen in as we review the USPSTF’s recently proposed recommendations for screening women who are at risk for developing osteoporosis. Gain confidence to navigate these changes and engage patients in shared decision-making to ensure timely, evidence-based preventive care. Episode resource links: JAMA. 2025;333(6):498–508. doi:10.1001/jama.2024.27154 Guest: Robert A. Baldor MD, FAAFP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com  

Credits: 0.50 AMA PRA Category 1 Credits™, 0.50 ABIM MOC or 0.42 AANP including 0.21 AANP Pharm CME/CE Information and Claim Credit: https://www.pri-med.com/online-cme-ce/podcast/patients-experiences-living-with-mash-role-pcps-can-play Overview: Hear directly from a patient living with MASH as he shares his compelling journey from diagnosis to treatment, shedding light on the real-world challenges and frustrations patients face. His story reveals how this often-missed condition can be better recognized and managed in primary care. Learn how to close care gaps, strengthen patient communication, and apply current guidelines to reduce cardiometabolic risk and improve outcomes in MASLD and MASH. A must-listen for primary care clinicians who care for at-risk patients on a daily basis

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-441 Overview: Explore the evidence behind inspiratory and expiratory strength training to improve sleep quality, reduce daytime fatigue, ease COPD symptoms, and lower blood pressure. This episode offers practical guidance on how you can integrate this simple, affordable intervention to support better breathing and overall health in your patients. Episode resource links: OSA: Journal of Sleep Research. 2024;33(3):e13941. doi:10.1111/jsr.13941. Sleep & Breathing = Schlaf & Atmung. 2022;26(4):1527-1537. doi:10.1007/s11325-021-02536-4. HTN: Journal of Applied Physiology (Bethesda, Md. : 1985). 2020;129(3):449-458. doi:10.1152/japplphysiol.00024.2020. COPD: Chest. 2003;124(4):1357-64. doi:10.1378/chest.124.4.1357. Sleep: Sleep. 2016;39(6):1179-85. doi:10.5665/sleep.5826. Guest: Robert A. Baldor MD, FAAFP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-440 Overview: Explore current and emerging treatments for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), a debilitating condition with no known cause or cure. Learn how oxaloacetate may offer new hope for patients struggling with ME/CFS, and gain practical guidance to support informed, evidence-based conversations with your patients. Episode resource links: Cash A, Vernon SD, Rond C, Bateman L, et al. RESTORE ME: a RCT of oxaloacetate for improving fatigue in patients with myalgic encephalomyelitis/chronic fatigue syndrome. Front Neurol. 2024 Nov 27;15:1483876.  Cash A, Kaufman DL. Oxaloacetate Treatment For Mental And Physical Fatigue In Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Long-COVID fatigue patients: a non-randomized controlled clinical trial. J Transl Med. 2022 Jun 28;20(1):295.  CDC ME/CFS Basics Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Guest: Alan M. Ehrlich, MD, FAAFP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-439 Overview: Nocturnal leg cramps (NLCs) are common in older adults, but current treatments often fall short or carry risks. Listen in as we explore new evidence on the safety and efficacy of vitamin K2 as a potential treatment for NLCs. Come away with practical insights to help you improve the sleep and quality of life of your patients. Episode resource links: JAMA Intern Med. 2024;184(12):1443-1447. doi:10.1001/jamainternmed.2024.5726 Guest: Robert A. Baldor MD, FAAFP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-438 Overview: In this episode, we review a major umbrella study linking physical activity to improvements in memory, executive function, and general cognition—offering you practical insights to guide patient counseling and provide evidence-based, nonpharmacologic strategies for dementia prevention and cognitive enhancement. Episode resource links: Singh B, Bennett H, Miatke A, et al. Br J Sports Med. doi:10.1136/ Guest: Robert A. Baldor MD, FAAFP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com  

We are living longer and healthier lives. Learn what to expect for your patients and yourself with age. We will review how to differentiate normal aging from disease processes that need further investigation and identify conditions more common with age using the 5Ms of Geriatrics framework.

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-437 Overview: This episode reviews the remarkable impact of the human papillomavirus (HPV) vaccine from 2008–2022, including significant declines in cervical precancer rates. Tune in for key data insights and updated HPV vaccination guidelines to help you close care gaps and strengthen cancer prevention efforts in your practice. Episode resource links: Gargano JW, Stefanos R, Dahl RM, et al. Trends in Cervical Precancers Identified Through Population-Based Surveillance — Human Papillomavirus Vaccine Impact Monitoring Project, Five Sites, United States, 2008–2022. MMWR Morb Mortal Wkly Rep 2025;74:96–101. DOI: http://dx.doi.org/10.15585/mmwr.mm7406a4 • HPV Vaccination Recommendations: Dosing and Schedule • Talking to parents about HPV vaccine Guest: Jill M. Terrien PhD, ANP-BC    Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com   

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-436 Overview: Many patients with chronic obstructive pulmonary disease (COPD) are improperly treated with inhaled corticosteroids (ICS), increasing their risk of harm. This episode explores the latest evidence on long-term ICS risks and provides practical guidance to help you align COPD care with current guidelines—improving outcomes while minimizing adverse effects like pneumonia, cataracts, type 2 diabetes mellitus, and osteoporosis. Episode resource links: Pace WD, Callen E, Gaona-Villarreal G, Shaikh A, Yawn BP. Adverse outcomes associated with inhaled corticosteroid use in individuals with chronic obstructive pulmonary disease. Ann Fam Med. 2025;23(2):127-135. doi:10.1370/afm.240030 Pocket Guide to COPD Diagnosis, Management, and Prevention: A Guide for Healthcare Professionals. 2025 Edition. Global Initiative for Chronic Obstructive Lung Disease. https://goldcopd.org/2025-gold-report/ Guest: Jillian Joseph, PA-C   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com   

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-435 Overview: In this episode, we discuss how screen time—from adolescence through adulthood—can disrupt sleep more than we might realize. Hear what the latest research says about topics like blue light and sleep duration, discover practical strategies to sleep smarter in this digital world, and learn how sleep deprivation can impact the health of your patients. Episode resource links: Zhong, C., Masters, M., Donzella, S. M., Diver, W. R., & Patel, A. V. (2025). Electronic Screen Use and Sleep Duration and Timing in Adults. JAMA Network Open, 8(3), e252493-e252493. Liu, Y. (2016). Prevalence of healthy sleep duration among adults—United States, 2014. MMWR. Morbidity and mortality weekly report, 65. Centers for Disease Control and Prevention (CDC). (2017). Announcement: sleep awareness week, April 23–29, 2017. Morb Mortal Wkly Rep (MMWR), 66(15), 411. Chaput, J. P., Dutil, C., Featherstone, R., Ross, R., Giangregorio, L., Saunders, T. J., ... & Carrier, J. (2020). Sleep duration and health in adults: an overview of systematic reviews. Applied Physiology, Nutrition, and Metabolism, 45(10), S218-S231. Hartley, S., Royant-Parola, S., Zayoud, A., Gremy, I., & Matulonga, B. (2022). Do both timing and duration of screen use affect sleep patterns in adolescents?. Plos one, 17(10), e0276226. Salfi, F., Amicucci, G., Corigliano, D., D’Atri, A., Viselli, L., Tempesta, D., & Ferrara, M. (2021). Changes of evening exposure to electronic devices during the COVID-19 lockdown affect the time course of sleep disturbances. Sleep, 44(9), zsab080. He, J. W., Tu, Z. H., Xiao, L., Su, T., & Tang, Y. X. (2020). Effect of restricting bedtime mobile phone use on sleep, arousal, mood, and working memory: a randomized pilot trial. PloS one, 15(2), e0228756. Guest: Mariyan L. Montaque, DNP, FNP-BC   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com