Glioblastoma aka GBM

In this episode, we visit KU Leuven in Belgium to explore GLIOMATCH, a groundbreaking European research initiative working to improve outcomes for adults and children with glioblastoma through collaboration across neurosurgery, oncology, immunology, and spatial omics. We speak with the experts leading this innovative work. Frederik De Smet, Professor and GLIOMATCH Project Coordinator at KU Leuven, outlines the vision for the project and how it brings together multiple disciplines to tackle one of the most challenging forms of cancer. Steven De Vleeschouwer, MD, PhD, Neurosurgeon and expert in immunotherapy trials, shares how surgical intervention plays a key role not only in treatment but also in advancing research. Paul M. Clement, MD, Medical Oncologist specializing in adult neuro-oncology, discusses the complexities of post-surgical care and how GLIOMATCH is helping improve decision-making. Sandra Jacobs, MD, Pediatric Neuro-Oncologist, highlights the unique challenges in treating children and the need for tailored research approaches. Thierry Voet, PhD, Chair of the Leuven Institute for Single-Cell Omics, explains how cutting-edge spatial omics is transforming our understanding of glioblastoma biology. Abhishek D. Garg, PhD, Tumor Immunology Specialist, shares how data science and deep immune profiling are driving new insights into overcoming immunotherapy resistance. GLIOMATCH is a testament to the power of collaboration in pushing the boundaries of glioblastoma research and offering hope for patients and families worldwide. This work is funded by the European Union. Views and opinions expressed are those of the author(s) only and do not necessarily reflect those of the European Union or the European Health and Digital Executive Agency (HaDEA). Neither the European Union nor the granting authority can be held responsible for them. This work is also supported by Innovate UK [grant number 10113516] and the Swiss State Secretariat for Education, Research and Innovation (SERI) under the contract number 23.00607. Learn more at www.gliomatch.eu This episode is intended for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider for guidance specific to your health or treatment plan.

In this episode, we visit Bambino Gesù Children’s Hospital in Rome to explore the pioneering pediatric brain tumor research being led by Maria Vinci, MD. Her team focuses on high-grade pediatric brain tumors including diffuse midline gliomas, with the goal of advancing more personalized and effective therapies for children around the world. We tour three key research labs that play a central role in their work: the patient-derived model lab, the high-content imaging lab, and the Hyperion lab, which uses advanced single-cell spatial proteomics to better understand the tumor microenvironment. Together, these technologies allow Dr. Vinci’s team to investigate how these aggressive tumors develop and respond to potential treatments. This episode provides a rare behind-the-scenes look at how leading scientists and clinicians in Rome are pushing the boundaries of pediatric neuro-oncology and working to bring new hope to families facing devastating diagnoses. This episode is intended for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider for guidance specific to your health or treatment plan.

In this episode, we’re in Zurich at the University Children’s Hospital to explore the pediatric brain tumor research being led by Dr. Javad Nazarian, whose lab focuses on diffuse midline gliomas (DMGs) and other rare, aggressive pediatric brain tumors. Dr. Nazarian’s work, supported in part by the Glioblastoma Research Organization through Project DeLaRoSa, is aimed at uncovering the biological underpinnings of these tumors to open doors for more targeted and effective treatments. We speak with several members of his research team — including Kamil Wojnicki, PhD, Matteo Bimbati, MSc, and Bettina Kritzer, MSc — about current challenges in the field, the value of interdisciplinary collaboration, and the future of pediatric neuro-oncology. We also hear perspectives from Sandra Fernandes Dias, MD, and Prof. Dr. Michael Grotzer, both of whom work at the University Children’s Hospital, on the clinical realities of treating these diseases and how research and patient care intersect in a hospital setting. This episode offers a behind-the-scenes look at a globally collaborative effort to improve outcomes for children and families facing devastating diagnoses. This episode is intended for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider for guidance specific to your health or treatment plan.

In the Season 3 finale of the Glioblastoma AKA GBM Podcast, social media influencer Ellie Thumann shares her heartfelt experiences following the loss of her grandfather, known affectionately as "Pop Pop," to glioblastoma. Ellie discusses the profound impact her grandfather's illness had on her and her family, reflecting on the cherished moments and the challenging journey through grief. Through her narrative, Ellie touches on themes of memory, loss, and legacy, providing a deeply personal insight into the emotional landscape that accompanies the loss of a loved one.

In this episode of The Glioblastoma AKA GBM Podcast, we welcome Doug Malchow, who transformed his personal tragedy into a source of support and solidarity for others. After losing his father to glioblastoma, Doug took to Instagram and TikTok to share his journey through grief and caregiving. In candid posts, he expresses the emotional challenges and the profound impact of his father's illness and passing. Through his social media platform, Doug provides a space for others to connect, share their stories, and find comfort in communal grieving. This episode delves into the realities of caregiving, the grieving process, and the power of sharing one’s personal story on social media to help others feel less alone. Episode Sponsor: Novocure. Visit https://www.novocure.com/ to learn more. Trigger Warning: This episode includes discussions on terminal illness, loss, and grief. Visit to Learn More: For more information and support resources, visit GBMResearch.org. Disclaimer: The content discussed on The Glioblastoma AKA GBM Podcast is based on personal stories and experiences. It is not intended as medical advice. Always consult with healthcare professionals for medical guidance and treatment options.

In this episode of The Glioblastoma AKA GBM Podcast, Dr. Ashish Shah, Assistant Professor of Neurological Surgery at the University of Miami Miller School of Medicine and Director of Clinical Trials and Translational Research within the University of Miami Brain Tumor Initiative, dives deep into his groundbreaking research on glioblastoma. Dr. Shah discusses a fascinating study revealing how fragments of a retrovirus, integrated into the human genome millions of years ago, are implicated in the proliferation and progression of glioblastoma, the most aggressive primary brain tumor. This episode explores how these findings from Dr. Shah's research at the Sylvester Comprehensive Cancer Center could revolutionize our understanding of glioblastoma and lead to novel treatment strategies. We also delve into the potential of antiretroviral agents and gene therapy as innovative approaches to target these viral fragments, opening new avenues for combatting this challenging cancer. Episode Sponsor: Novocure. Visit https://www.novocure.com/ to learn more. Trigger Warning: This episode includes discussions on medical conditions, cancer treatments, and genetic research. Visit to Learn More: For more information and support resources, visit GBMResearch.org. Disclaimer: The content discussed on The Glioblastoma AKA GBM Podcast is based on personal stories and experiences. It is not intended as medical advice. Always consult with healthcare professionals for medical guidance and treatment options.

In this episode of The Glioblastoma AKA GBM Podcast, we are joined by Dr. Betsy Grunch, renowned neurosurgeon and social media educator, known online as @LadySpineDoc. Born and raised in Gainesville, Georgia, Dr. Grunch has built a distinguished career in neurosurgery, specializing in minimally invasive spine techniques and neurotrauma. Recently named among America's Best Spine Surgeons by Newsweek in 2024, she has taken her expertise to social media to demystify complex medical concepts and educate a broader audience. During our discussion, Dr. Grunch shares insights into the dynamic field of neurosurgery, her approach to patient care, and how she utilizes platforms like Instagram and Twitter to bridge the gap between advanced medical science and public understanding. Join us as Dr. Grunch sheds light on the challenges and advancements in neurosurgery while promoting educational outreach through her social media presence. Episode Sponsor: Novocure - Learn more about their innovative cancer treatments Follow Dr. Betsy Grunch on Instagram: @LadySpineDoc Trigger Warning: This episode includes discussions on medical conditions and surgical treatments. Visit to Learn More: For more information and support resources, visit GBMResearch.org. Disclaimer: The content discussed on The Glioblastoma AKA GBM Podcast is based on personal stories and experiences. It is not intended as medical advice. Always consult with healthcare professionals for medical guidance and treatment options.

In this timely episode of The Glioblastoma AKA GBM Podcast, released just after Glioblastoma Awareness Day, we welcome John Furey, the CEO of Imvax, Inc. John discusses the groundbreaking work of Imvax, particularly their lead product candidate, IGV-001, currently in a phase 2b randomized trial for newly diagnosed glioblastoma multiforme (GBM). He shares insights into the unique challenges and opportunities of developing patient-specific vaccines and immunotherapy strategies in the fight against GBM. The conversation also delves into the broader landscape of clinical trials, highlighting how these innovative approaches are transforming patient care and outcomes in oncology. Join us to understand more about the cutting-edge science that could potentially revolutionize treatment for glioblastoma and beyond. Episode Sponsor: IMVAX. Visit https://www.imvax.com/ to learn more. Trigger Warning: This episode includes discussions on medical conditions and cancer treatments. Visit to Learn More: For more information and support resources, visit GBMResearch.org. Disclaimer: The content discussed on The Glioblastoma AKA GBM Podcast is based on personal stories and experiences. It is not intended as medical advice. Always consult with healthcare professionals for medical guidance and treatment options.

In this compelling episode of The Glioblastoma AKA GBM Podcast, we sit down with Rod Nordland, a distinguished foreign correspondent whose work has taken him across more than 150 countries. Rod shares his personal journey with glioblastoma, discussing not only the challenges he's faced but also his advocacy for disability awareness. He introduces his new book, "Waiting for the Monsoon," reflecting his rich experiences and the profound insights he's gained. Special guest Leila, Rod’s partner, joins the conversation, adding depth to the discussion of Rod's diagnosis and their shared path forward. This episode offers a unique look at the intersection of a life spent in journalism and a personal battle with a daunting diagnosis. Episode Sponsors: Plus Therapeutics and Imvax Trigger Warning: This episode includes discussions on medical conditions, cancer treatments, death, grief, therapy, and personal loss. Visit to Learn More: For more information and support resources, visit GBMResearch.org. Disclaimer: The content discussed on The Glioblastoma AKA GBM Podcast is based on personal stories and experiences. It is not intended as medical advice. Always consult with healthcare professionals for medical guidance and treatment options.

In this heartfelt episode of The Glioblastoma AKA GBM Podcast, we are joined by Holly Gainsboro, a grief specialist and founder of Golden Heart Grief Support and Education. Holly shares her profound journey of loss and transformation following her late husband's diagnosis with glioblastoma. Through her personal experiences and extensive training, Holly has developed unique insights into navigating grief, particularly in the context of glioblastoma-related loss. She discusses the emotional whirlwind from diagnosis to her husband’s passing and how these experiences propelled her into supporting others as they navigate their own paths of grief. Listen as Holly offers wisdom on coping with the complex emotions of grief and finding hope amidst despair. Episode Sponsor: Plus Therapeutics. Visit https://plustherapeutics.com/ to learn more. Trigger Warning: This episode includes discussions on grief, terminal illness, and bereavement. Visit to Learn More: For more support and resources, visit GBMResearch.org and explore Holly's services at goldenheartgrief.com. Disclaimer: The content discussed on The Glioblastoma AKA GBM Podcast is based on personal stories and experiences. It is not intended as medical advice. Always consult with healthcare professionals for medical guidance and treatment options.

Dive into the latest developments in glioblastoma treatment with Tamika Wong, MPH, Director of Clinical Research in Neurosurgery, and Dr. Morana Vojnic, Medical Oncologist and Director of Oncologic Services at the Brain and Spine Metastases Program, both from Lenox Hill Hospital. This episode offers a deep dive into groundbreaking clinical trials and treatments, clarifying complex brain tumor and glioblastoma terminology for a broader understanding. Listen as Tamika and Dr. Vojnic highlight the critical role of hope and advanced care strategies in improving patient outcomes. Episode Sponsor: Imvax. To learn more visit https://www.imvax.com/. Trigger Warning: This episode includes discussions on medical conditions, cancer treatments, and clinical trials. Visit to Learn More: For more information and support resources, visit GBMResearch.org. Disclaimer: The content discussed on The Glioblastoma AKA GBM Podcast is based on personal stories and experiences. It is not intended as medical advice. Always consult with healthcare professionals for medical guidance and treatment options.

In this deeply moving episode of The Glioblastoma AKA GBM Podcast, we revisit the extraordinary life of David Fitting, known as the longest surviving glioblastoma patient in the USA. David first joined us to share his initial battle with brain cancer as a child and his miraculous journey to remission. Now, he returns to discuss his life post-recovery, the challenges of facing cancer multiple times, and his subsequent diagnosis and fight against osteosarcoma. Beyond his personal battles, David dives into his impactful advocacy work, providing hope and guidance to others navigating similar paths. This episode is a testament to resilience and the power of a positive outlook in the face of life's toughest challenges. Trigger Warning: This episode includes discussions on medical conditions, cancer treatments, and emotional challenges. Visit to Learn More: For more information and support resources, visit GBMResearch.org. Episode Sponsor: Novocure. Visit https://www.novocure.com/ to learn more. Disclaimer: The content discussed on The Glioblastoma AKA GBM Podcast is based on personal stories and experiences. It is not intended as medical advice. Always consult with healthcare professionals for medical guidance and treatment options.

In this insightful episode of The Glioblastoma AKA GBM Podcast, we're joined by Dr. Marc Hedrick, President and CEO of Plus Therapeutics. Dr. Hedrick brings his extensive background in surgery and regenerative medicine to discuss the forefront of cancer treatment—targeted radiotherapeutics. He delves into the exciting developments of the ReSPECT GBM clinical trial, addressing the challenges and innovative approaches to treating recurrent glioblastoma, a notoriously difficult condition to manage. Listen in as Dr. Hedrick shares his unique insights on the potential of new therapies and the future of glioblastoma treatment. Trigger Warning: This episode includes discussions on medical conditions, cancer treatments, and clinical trials. For more information and support resources, visit GBMResearch.org. Episode Sponsor: Plus Therapeutics. Visit https://plustherapeutics.com/for-patients/ to learn more. Disclaimer: The content discussed on The Glioblastoma AKA GBM Podcast is based on personal stories and experiences. It is not intended as medical advice. Always consult with healthcare professionals for medical guidance and treatment options.

In this inspiring episode of The Glioblastoma AKA GBM Podcast, we're joined by Dr. Sheri Dewan, a trailblazer among the elite group of female neurosurgeons. With a career that spans across continents and cultures, Dr. Dewan brings her unique perspective to some of the most complex neurosurgical challenges. She discusses her groundbreaking new book, "Cutting a Path," her dedication to global healthcare, and her experiences with charity surgery in Southern India. Additionally, Dr. Dewan delves into medical intricacies and advanced surgical techniques that have never before been discussed on our show. Join us as we explore the intersection of gender, innovation, and compassion in the field of neurosurgery with one of its most dynamic practitioners. Trigger Warning: This episode includes discussions on surgical procedures and medical conditions. For more information and support resources, visit GBMResearch.org. To purchase Cutting a Path: The Power of Purpose, Discipline, and Determination, visit: https://www.amazon.com/Cutting-Path-Purpose-Discipline-Determination/dp/161254620X. Episode Sponsor: Novocure. Visit https://www.novocure.com/ to learn more. Disclaimer: The content discussed on The Glioblastoma AKA GBM Podcast is based on personal stories and experiences. It is not intended as medical advice. Always consult with healthcare professionals for medical guidance and treatment options.

Join us for an enlightening episode of The Glioblastoma AKA GBM Podcast with Dr. Netanel (Nati) Ben-Shalom, a trailblazer in neuroplastic and reconstructive surgery. Dr. Ben-Shalom, the world’s first neurosurgeon to complete the prestigious Johns Hopkins Neuroplastic and Reconstructive Surgery fellowship, discusses his innovative approaches in neurosurgery that not only enhance surgical outcomes but also significantly improve the quality of life for patients with brain tumors. In this episode, learn about the revolutionary techniques and implantable biomaterials that are transforming patient care, how 3D printing and third-generation cranial implants are used to minimize physical deformities and enhance recovery, and why a holistic approach is crucial for successful treatment outcomes. Trigger Warning: This episode includes discussions on medical conditions, surgical procedures, and cancer treatments. For more information and support resources, visit GBMResearch.org. Episode Sponsor: Plus Therapeutics. Visit https://plustherapeutics.com/for-patients/ to learn more. Disclaimer: The content discussed on The Glioblastoma AKA GBM Podcast is based on personal stories and experiences. It is not intended as medical advice. Always consult with healthcare professionals for medical guidance and treatment options.

In this compelling episode of The Glioblastoma AKA GBM Podcast, we welcome Jordy Glassner, a dedicated therapist who brings a unique dual perspective as both a caregiver and a current patient battling glioblastoma. Jordy opens up about her diagnosis, and how her professional background in therapy has shaped her approach to treatment and self-care. Join us as we explore the emotional and psychological impacts of glioblastoma through Jordy's eyes, offering insights into resilience, therapy, and maintaining hope in the face of adversity. Trigger Warning: This episode includes discussions on medical conditions, cancer treatments, and emotional health challenges. For more information and support resources, visit GBMResearch.org. Episode sponsor: Imvax *Disclaimer: The content discussed on The Glioblastoma AKA GBM Podcast is based on personal stories and experiences. It is not intended as medical advice. Always consult with healthcare professionals for medical guidance and treatment options.

Join us for the Season 3 premiere of The Glioblastoma AKA GBM Podcast, where we delve into the heart and mind of multi-platinum singer-songwriter Mike Posner. In this deeply personal episode, Mike shares his journey through the harrowing landscape of glioblastoma as he witnessed his father’s battle with this aggressive form of brain cancer. As we explore the layers of grief and healing, Mike opens up about how this experience has reshaped his creative process and his outlook on life. In this conversation, we cover: The profound impact of his father’s glioblastoma diagnosis and the family’s journey through treatment and loss. How grief has influenced Mike’s music and artistic expression. Cherished advice from his dad that continues to guide him. Mike's vision for living a meaningful life in the wake of personal tragedy. Mike Posner, known for his hit songs and remarkable resilience, brings a unique perspective on dealing with loss, channeling creativity, and finding purpose amidst pain. This episode is a touching reflection on love, loss, and legacy. Trigger Warnings: This episode contains discussions on medical conditions, cancer diagnosis, and end-of-life themes. For more insights and to support the Glioblastoma Research Organization, please visit GBMResearch.org. Disclaimer: The content shared on The Glioblastoma AKA GBM Podcast represents personal stories and is intended for informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your healthcare provider with any questions regarding a medical condition.

The finale of Season 2 of Glioblastoma aka GBM is here, and to wrap up the season we'd like to welcome Elissa Barbach to the show. Elissa was a caregiver and lost her husband to glioblastoma in 2018, and has learned to rebuild her life after losing her best friend - while still being incredibly gracious, kind, loving, caring, positive - and overall, a great mom. On this episode, you'll hear us chat about: The early stages of finding out her husband had a brain tumor Being a caregiver on her own The end of life progression Her grief and how she's worked through it Her emotional support puppy -& so much more TO LEARN MORE ABOUT THE ORGANIZATION VISIT GBMRESEARCH.ORG. Trigger warnings may include: cancer, end of life, end of life progression, death, terminal illness, grief, loss of spouse, and being so unbelievably proud of your mom for sharing her story. SEASON SPONSORS: BIODEXA PHARMACEUTICALS, GAMMA TILE, NOVOCURE, AND ROON. As always, the information that is discussed in Glioblastoma AKA GBM is not meant to treat, diagnose, or prevent any disease. What we and our guests share are personal stories of what has worked for the individuals in question, and should not be taken as medical advice or opinion, and is not a substitute for medical advice. If you have any questions about your own situation, always consult with your medical provider and healthcare team.

David M. Ashley, PhD, FRACP, MBBS (Hons), Director of the Preston Robert Tisch Brain Tumor Center at Duke joins us on this episode to discuss his history in neuro-oncology, innovations happening at the Brain Tumor Center, clinical trial advancements, and his past-life as a surfer. On this episode, you'll hear us chat about: - What led him to Duke - The world-renown Duke Polio clinical trial & it's comeback - His work in discovering how scientists can learn to prevent brain tumors - The brain & it's own lymphatic system - How research is translated from in-vitro to in-vivo -& so much more TO LEARN MORE ABOUT THE ORGANIZATION VISIT GBMRESEARCH.ORG. Trigger warnings may include: cancer, cancer treatment, clinical trials, scientific terminology, and realizing that this episode may have taught you more in 39 minutes than any of your high school science classes did. SEASON SPONSORS: BIODEXA PHARMACEUTICALS, GAMMA TILE, NOVOCURE, AND ROON. As always, the information that is discussed in Glioblastoma AKA GBM is not meant to treat, diagnose, or prevent any disease. What we and our guests share are personal stories of what has worked for the individuals in question, and should not be taken as medical advice or opinion, and is not a substitute for medical advice. If you have any questions about your own situation, always consult with your medical provider and healthcare team.

Vidya Gopalakrishnan, Ph.D is a researcher at MD Anderson Cancer Center, an esteemed member of the Glioblastoma Research Organization Medical Advisory Board, and has a laboratory focused on research for DIPG (Diffuse Intrinsic Pontine Glioma). On this episode, you'll hear us chat about: - What sparked Vidya's interest in working on brain tumor research - Immunotherapy at MD Anderson Cancer Center - The science behind brain tumors - The difference between tumor types and tumor locations - Her hopes for advances in the field -& so much more TO LEARN MORE ABOUT THE ORGANIZATION VISIT GBMRESEARCH.ORG. Trigger warnings may include: cancer, cancer treatment, and significant medical terminology. SEASON SPONSORS: BIODEXA PHARMACEUTICALS, GAMMA TILE, NOVOCURE, AND ROON. As always, the information that is discussed in Glioblastoma AKA GBM is not meant to treat, diagnose, or prevent any disease. What we and our guests share are personal stories of what has worked for the individuals in question, and should not be taken as medical advice or opinion, and is not a substitute for medical advice. If you have any questions about your own situation, always consult with your medical provider and healthcare team.