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Symptomatic: A Medical Mystery Podcast
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Symptomatic: A Medical Mystery Podcast

Author: iHeartPodcasts

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How terrifying would it be to fight an unknown enemy? One you don’t recognize and didn’t see coming? What if that enemy was coming from within; a disease that even doctors couldn’t identify? Nearly half of all Americans suffer from some chronic illness and many struggle for an accurate diagnosis.


Every other week on Symptomatic, host Lauren Bright Pacheco unravels the medical mystery of a patient’s baffling symptoms and explores how their lives were turned upside down in search of answers. 


From the first signs of trouble, through a swirl of misdirection and failed treatment attempts, to the final relief at a confirmed diagnosis - these are their stories. This is Symptomatic.


We want to hear from you! Tell us what you think of the show or share your own medical mystery by emailing us at [email protected].

52 Episodes
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Case #37: Grace

Case #37: Grace

2026-10-2751:03

Grace Sullivan was only 17 when she was hit by unexplained bouts of uncontrollable vomiting that would last for days, even weeks. Countless trips to the ER, tests with no conclusive results, and no clear indicator for the root cause. After 19 hospitalizations in the span of two years - Grace believed she may never get better…especially when it became clear that the thing causing these episodes was something she had become completely reliant on.   We want to hear from you! Share your own medical mystery or tell us about the episode you connected with the most at [email protected].   *  *  *  *  *  * ****** SPOILER ALERT BELOW ******   You can learn more about Dr. Andrew Meltzer's work on CHS here: https://pubmed.ncbi.nlm.nih.gov/39985554/. If you or a loved one are struggling with addiction, you can find resources at usa.gov/substance-abuse.See omnystudio.com/listener for privacy information.
Case #36: Travis

Case #36: Travis

2026-10-2052:20

Travis Bolt was a charismatic kid with an old soul…and a natural talent for music. When Travis turns eight years old, he begins to experience uncontrollable muscle movements that continue to escalate in intensity. He starts getting in trouble in school, injuring himself inadvertently, and faces years of medical trial treatments that create new health problems. All the while, Travis endures relentless bullying at school—not only from fellow students, but from teachers as well, the result of ignorance and a lack of understanding about his condition—until he stumbles upon an unconventional treatment that changes everything.   We want to hear from you! Share your own medical mystery or tell us about the episode you connected with the most at [email protected].   Travis's music was provided by Gravel Road Records and can be found on your favorite streaming platforms by searching Travis Bolt. His new album is called Burning Bridges.   *  *  *  *  *  * ****** SPOILER ALERT BELOW ******   If you'd like to learn more about the Tourette's Association of America, you can find them at tourette.org. See omnystudio.com/listener for privacy information.
Let's revisit one of our favorite episodes from Season 1. Zach was your average 11-year-old who loved pizza, sports, and going fishing with his Dad until an incident at a baseball game changed his life forever. As an illness quickly takes hold and wreaks havoc on his body, it’s a race against the clock to figure out what’s happening and save Zach’s life. All new medical mysteries are back next week! *  *  *  *  *  * ****** SPOILER ALERT BELOW ****** To find out more information on Sepsis, visit Sepsis.org.See omnystudio.com/listener for privacy information.
Case #35: Len (Pt. 2)

Case #35: Len (Pt. 2)

2026-10-0640:45

This is part two of Len Geiger’s story. The last we heard from Len, he was flying over the handlebars of his mountain bike only three months after receiving a miraculous lung transplant that had saved his life.    We want to hear from you! Share your own medical mystery or tell us about the episode you connected with the most at [email protected]. *  *  *  *  *  * ****** SPOILER ALERT BELOW ******   You can learn more about Alpha-1 Antitrypsin Deficiency through the Alpha-1 Foundation at https://alpha1.org/ or alphaid.com where you can request a free Alpha-1 test kit.   If you want to learn more about life saving organ donations you can go to Donate Life America at https://donatelife.net/ or OrganDonor.gov. See omnystudio.com/listener for privacy information.
Case #35: Len

Case #35: Len

2026-09-2949:052

Len Geiger was a perfectly healthy, athletic young man with no signs of illness…but when Len enters his late twenties he starts falling ill with chronic chest infections. By age thirty - Len begins to experience breathlessness so debilitating he can barely walk across a parking lot. 10 years after the onset of symptoms, Len is dying from lungs that can no longer function due to a disease often overlooked in testing.    We want to hear from you! Share your own medical mystery or tell us about the episode you connected with the most at [email protected].   *  *  *  *  *  * ****** SPOILER ALERT BELOW ******   You can learn more about Alpha-1 Antitrypsin Deficiency through the Alpha-1 Foundation at https://alpha1.org/ or alphaid.com where you can request a free Alpha-1 test kit. If you want to learn more about life saving organ donations you can go to Donate Life America at https://donatelife.net/ or OrganDonor.gov.See omnystudio.com/listener for privacy information.
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