Breast Cancer Trials

Could Patients with Breast Cancer Safely Skip Radiation & the Potential Side Effects? Inside the ROSALIE Clinical TrialCould skipping radiation after breast-conserving surgery be safe for some patients? The ROSALIE trial is exploring this possibility. In this episode, we sit down with Professor Boon Chua, Radiation Oncologist and Professor of Medicine at the University of New South Wales, who leads the Breast Cancer Trials ROSALIE clinical trial.  Professor Chua discusses how the study aims to de-escalate treatment for women with early-stage breast cancer who achieve a complete response to chemotherapy, potentially reducing side effects without compromising outcomes.  (2:06) What is the ROSALIE clinical trial hoping to find out?(2:51) How could this research change the way we treat breast cancer in the future, especially for patients with early-stage disease?(3:30) What would you like patients and the public to understand about the importance of participating in trials like this?Tune in for a deep dive into this important research.⁠⁠⁠⁠Donate to Support Life-Saving Research⁠⁠⁠⁠Like this episode? ⁠⁠⁠⁠Find more Breast Cancer Trials Podcast Episodes here⁠⁠⁠⁠Follow Breast Cancer Trials on Social Media: Instagram:⁠ ⁠⁠⁠@breastcancertrials⁠⁠⁠⁠  Facebook:⁠ ⁠⁠⁠Breast Cancer Trials⁠⁠⁠⁠ LinkedIn: ⁠⁠⁠⁠Breast Cancer Trials⁠⁠⁠⁠ X: ⁠⁠⁠⁠@BCTrialsANZ⁠⁠⁠⁠Guest: Medical Oncologist, Dr Boon Chua.Thank you for listening! If you found this episode valuable, please share it with your loved ones and help spread awareness about the importance of clinical trials research.

Neoadjuvant Now: What's Next in Pre-Surgical Breast Cancer Treatment?More and more breast cancer patients are now receiving treatment before surgery - but what’s next for this approach? In this episode, we look at how neoadjuvant therapy is changing, the new treatments being tested, and what it could mean for patients in the future.Hear from the Head of the International Breast Cancer Centre (IBCC), Dr Javier Cortes as he discusses:(0:30) What neoadjuvant therapy is, and why it's used throughout breast cancer treatment. (1:52) The new drugs and treatment combinations that are currently being explored in the neoadjuvant setting.(3:01) How neoadjuvant therapy has evolved in the last decade. (3:50) The biggest benefits of giving therapy before surgery rather than after. Tune in for a deep dive into this important research.⁠⁠⁠Donate to Support Life-Saving Research⁠⁠⁠Like this episode? ⁠⁠⁠Find more Breast Cancer Trials Podcast Episodes here⁠⁠⁠Follow Breast Cancer Trials on Social Media: Instagram:⁠ ⁠⁠@breastcancertrials⁠⁠⁠  Facebook:⁠ ⁠⁠Breast Cancer Trials⁠⁠⁠ LinkedIn: ⁠⁠⁠Breast Cancer Trials⁠⁠⁠ X: ⁠⁠⁠@BCTrialsANZ⁠⁠⁠Guest: Medical Oncologist, Dr Javier Cortes, from Barcelona.Thank you for listening! If you found this episode valuable, please share it with your loved ones and help spread awareness about neoadjuvant therapy.

Next Gen Oncology: Insights for Trainees and Early-Career CliniciansAre you a trainee or early career professional in oncology looking to connect, learn, and grow? In this episode, we highlight the Trainee and Early Career Day at the Breast Cancer Trials Annual Scientific Meeting. A unique opportunity to network with peers, gain insights from leading researchers, and kickstart your professional development in the field of breast cancer research.Hear from Breast Cancer Trials Clinical Fellow, Dr Michelle Li, and former Fellow Dr Adam Ofri as they discuss:(0:26) What the Trainee and Early-Career Day is, and who it is aimed at.(2:38) What you can expect from attending the Trainee and Early-Career Day.(4:04) How this session will help those who are starting out in breast cancer research or clinical practice. (6:04) Why it's so important that the next generation of researchers and clinicians become involved with Breast Cancer Trials. Tune in for a deep dive into this important topic.Donate to Support Life-Saving Research⁠⁠⁠Like this episode? ⁠⁠⁠Find more Breast Cancer Trials Podcast Episodes here⁠⁠⁠Follow Breast Cancer Trials on Social Media: Instagram:⁠ ⁠⁠@breastcancertrials⁠⁠⁠  Facebook:⁠ ⁠⁠Breast Cancer Trials⁠⁠⁠ LinkedIn: ⁠⁠⁠Breast Cancer Trials⁠⁠⁠ X: ⁠⁠⁠@BCTrialsANZ⁠⁠⁠Guests: Medical Oncologist, Dr Michelle Li, and Breast Surgeon, Dr Adam Ofri.Thank you for listening! If you found this episode valuable, please share it with your colleagues. The Trainee and Early-Career Day is a free event designed for those in the early stages of their careers in medical, radiation, or surgical oncology. This multi-disciplinary event features expert presentations, MDT panel discussions, and valuable networking opportunities with leading researchers and international speakers.

Caring for the Caregivers: Preventing Burnout in OncologyWhat happens when the people caring for everyone else are running on empty? In this episode, we sit down with London-based Professor of psycho-oncology, Dame Lesley Fallowfield, to explore burnout, practical self-care strategies, and ways we can better support healthcare workers before exhaustion takes its toll.(5:22) Some of the key warning signs that a healthcare worker might be approaching burnout. (9:06) How leaders and managers can better recognise and respond to the needs of their teams.(10:39) Programs and initiatives that are making a difference in supporting staff.(12:40): The stigma that surrounds healthcare workers prioritising self-care, and what needs to happen in order for this culture to shift.Tune in for a deep dive into this important topic. ⁠⁠⁠Donate to Support Life-Saving Research⁠⁠⁠Like this episode? ⁠⁠⁠Find more Breast Cancer Trials Podcast Episodes here⁠⁠⁠Follow Breast Cancer Trials on Social Media: Instagram:⁠ ⁠⁠@breastcancertrials⁠⁠⁠  Facebook:⁠ ⁠⁠Breast Cancer Trials⁠⁠⁠ LinkedIn: ⁠⁠⁠Breast Cancer Trials⁠⁠⁠ X: ⁠⁠⁠@BCTrialsANZ⁠⁠⁠Guest: Professor Dame Lesley Fallowfield.Thank you for listening! If you found this episode valuable, please share it with your loved ones and help spread awareness about burnout in clinicians.

Intimacy and Insight: Sexual Health After Breast CancerSexual health after breast cancer is a topic too often left in the shadows - yet it profoundly affects quality of life both during and post-diagnosis. In this episode, Dr Belinda Yeo and Dr Virginia Baird open the conversation, sharing insights into how we can better support patients navigating intimacy, identity, and well-being after breast cancer treatment.In this episode, we sit down with Belinda and Virginia to discuss:(0:50) Why sexual health is such an important, but often overlooked, component of breast cancer care.(1:23) The most commonly identified sexual health issues that patients face.(07:20) The changes that need to happen within clinical practice to better support breast cancer patients.Tune in for a deep dive into this important research. ⁠⁠⁠Donate to Support Life-Saving Research⁠⁠⁠.Like this episode? ⁠⁠⁠Find more Breast Cancer Trials Podcast Episodes here⁠⁠⁠Follow Breast Cancer Trials on Social Media: Instagram:⁠ ⁠⁠@breastcancertrials⁠⁠⁠  Facebook:⁠ ⁠⁠Breast Cancer Trials⁠⁠⁠  LinkedIn: ⁠⁠⁠Breast Cancer Trials⁠⁠⁠ X: ⁠⁠⁠@BCTrialsANZ⁠⁠⁠Guests: Medical Oncologist Belinda Yeo, and Breast Clinician Virginia Baird.Thank you for listening! If you found this episode valuable, please share it with your loved ones and help spread awareness about breast cancer and sexual health. If you were interested in learning more listen to our online Q&A event, moderated by Author and Journalist Annabel Crabb, on Breast Cancer and Sex.

Choosing Your Path & Navigating Difficult Treatment DecisionsWhat happens when patients say ‘no’ to recommended treatments? The search for alternatives can be confronting for both patients and clinicians. Associate Professor Lesley Stafford explores why some patients take this path, what it means for their outcomes, and how the medical community can better navigate these difficult conversations.In this episode, we sit down with Lesley to discuss:(03:38) Some of the challenges that clinicians face when trying to support a patient who refuses a recommended treatment.(06:09) How to approach difficult conversations between patients and clinicians.(09:42) How to identify and select appropriate alternative therapies.Tune in for a deep dive into this important topic. ⁠⁠⁠Donate to Support Life-Saving Research⁠⁠⁠Like this episode? ⁠⁠⁠Find more Breast Cancer Trials Podcast Episodes here⁠⁠⁠Follow Breast Cancer Trials on Social Media: Instagram:⁠ ⁠⁠@breastcancertrials⁠⁠⁠  Facebook:⁠ ⁠⁠Breast Cancer Trials⁠⁠⁠ LinkedIn: ⁠⁠⁠Breast Cancer Trials⁠⁠⁠ X: ⁠⁠⁠@BCTrialsANZ⁠⁠⁠Guest: Clinical Psychologist, Associate Professor Lesley Stafford. Thank you for listening! If you found this episode valuable, please share it with your loved ones and help spread awareness about breast cancer.#breastcancer #cancertreatment #clinicalpsychology #breastcancertrials #clinicaltrials #research

Lotjpa Yapaneyepuk (Talk Together): Bridging Communities and Cancer Research Access to clinical trials isn't equal, and for Aboriginal and Torres Strait Islander peoples in Regional Victoria, barriers in accessing treatment for breast cancer remain. Dr Monica Green and Ms Leah Lindrea-Morrison share an initiative that's breaking down those barriers by talking together, listening deeply, and creating culturally safe pathways to clinical trials.In this episode, we sit down with Monica and Leah to discuss:(05:46) The historical, cultural, and systemic factors that influence trust in medical research and clinical trials, among indigenous communities. (08:25) Strategies or initiatives that have been effective in improving access or building those stronger relationships with communities in regional Victoria.(10:58) The role of community engagement and co-design in creating a more inclusive and culturally safe research opportunity for patients.(13:15) How clinicians and researchers can better support Aboriginal and Torres Strait Islander patients to consider and navigate trial participation. (16:00) What an equitable and accessible trial landscape looks like, and how we can get there.Tune in for a deep dive into this important research.⁠⁠⁠Donate to Support Life-Saving Research⁠⁠⁠Like this episode? ⁠⁠⁠Find more Breast Cancer Trials Podcast Episodes here⁠⁠⁠Follow Breast Cancer Trials on Social Media: Instagram:⁠ ⁠⁠@breastcancertrials⁠⁠⁠  Facebook:⁠ ⁠⁠Breast Cancer Trials⁠⁠⁠ LinkedIn: ⁠⁠⁠Breast Cancer Trials⁠⁠⁠ X: ⁠⁠⁠@BCTrialsANZ⁠⁠⁠Guests: Dr Monica Green and Ms Leah Lindrea-Morrison from Victoria.Music: Noa Zulu - MeditensionThank you for listening! If you found this episode valuable, please share it with your loved ones and help spread awareness about creating culturally safe pathways to clinical trials.

4CASTING the Future: Innovations in Triple Negative Breast Cancer Triple negative breast cancer remains one of the most challenging types to treat because it lacks the common treatment targets, grows and spreads aggressively, is highly diverse and currently has limited effective therapies - but new research is changing the story.  Associate Professor Rachel Dear takes us inside the 4CAST trial, showing how science moves from bench to bedside and what this could mean for the future of triple-negative breast cancer treatment. In this episode, we sit down with Rachel to discuss:(01:32) What makes triple-negative breast cancer so difficult to treat?(02:26) What pre-clinical findings led to the development of the 4CAST clinical trial?(08:37) The future of treatment for triple-negative breast cancer.Tune in for a deep dive into this important research.⁠⁠⁠Donate to Support Life-Saving Research⁠⁠⁠Like this episode? ⁠⁠⁠Find more Breast Cancer Trials Podcast Episodes here⁠⁠⁠Follow Breast Cancer Trials on Social Media: Instagram:⁠ ⁠⁠@breastcancertrials⁠⁠⁠  Facebook:⁠ ⁠⁠Breast Cancer Trials⁠⁠⁠ LinkedIn: ⁠⁠⁠Breast Cancer Trials⁠⁠⁠ X: ⁠⁠⁠@BCTrialsANZ⁠⁠⁠Guest: Medical Oncologist Rachel Dear, from Sydney.Thank you for listening! If you found this episode valuable, please share it with your loved ones and help spread awareness about triple-negative breast cancer.

Listen to Your Heart: Cardiac Care After Breast CancerBreast cancer treatments save lives, but sometimes it can leave the heart at risk. Professor Thomas Marwick sheds light on cardiac care for breast cancer survivors, exploring how monitoring and management strategies can protect heart health long after treatment ends. In this episode, we sit down with Thomas to discuss:(01:09) The common cardiac risks associated with breast cancer therapies.(02:24) Patient monitoring during and post-treatment.(04:07) Balancing effective treatment while protecting cardiac function.(05:19) Emerging technologies to improve detection and prevent cardiac events from occurring. Tune in for a deep dive into this important research.⁠⁠⁠Donate to Support Life-Saving Research⁠⁠⁠Like this episode? ⁠⁠⁠Find more Breast Cancer Trials Podcast Episodes here⁠⁠⁠Follow Breast Cancer Trials on Social Media:Instagram:⁠ ⁠⁠@breastcancertrials⁠⁠⁠  Facebook:⁠ ⁠⁠Breast Cancer Trials⁠⁠⁠ LinkedIn: ⁠⁠⁠Breast Cancer Trials⁠⁠⁠ X: ⁠⁠⁠@BCTrialsANZ⁠⁠⁠Guest: Cardiologist, Professor Thomas MarwickThank you for listening! If you found this episode valuable, please share it with your loved ones and help spread awareness about breast cancer and heart health.

Facing the Fear: Life After Breast CancerFor many breast cancer survivors, finishing treatment isn't the end of the journey - it's the beginning of new fears. Fear of recurrence is one of the most common and distressing challenges patients face. In this episode, Associate Professor Ben Smith unpacks why these fears occur, how they affect daily life, and what strategies can help patients move forward with confidence.In this episode, we sit down with Ben to discuss:(00:50) How we currently define fear of recurrence.(01:59) The factors that can contribute to a person's risk of having a fear of recurrence.(03:14) The impact that these fears can have on overall well-being.Tune in for a deep dive into this important research!⁠⁠⁠Donate to Support Life-Saving Research⁠⁠⁠Like this episode? ⁠⁠⁠Find more Breast Cancer Trials Podcast Episodes here⁠⁠⁠Follow Breast Cancer Trials on Social Media: Instagram:⁠ ⁠⁠@breastcancertrials⁠⁠⁠  Facebook:⁠ ⁠⁠Breast Cancer Trials⁠⁠⁠ LinkedIn: ⁠⁠⁠Breast Cancer Trials⁠⁠⁠ X: ⁠⁠⁠@BCTrialsANZ⁠⁠⁠Guest: Senior Implementation Scientist, Ben Smith, from SydneyThank you for listening! If you found this episode valuable, please share it with your loved ones and help spread awareness about the fear of breast cancer recurrence.

Screening Smarter: Personalised Approaches in Breast CareIs it time to rethink a ‘one size fits all’ approach to breast screening? Associate Professor Sanjay Warrier joins us to discuss the future of tailored breast screening, a personalised approach that could revolutionise how we detect breast cancer earlier and more effectively.In this episode, we sit down with Professor Warrier to discuss:(01:32) The main factors that might influence a more personalised screening strategy.(03:19) The current evidence about tailored screening.(04:27) How researchers are working to determine who might benefit from more/less intensive screening.(05:20) How close we are to seeing tailored breast screening become part of routine care.Tune in for a deep dive into this important research.⁠⁠⁠Donate to Support Life-Saving Research⁠⁠⁠Like this episode? ⁠⁠⁠Find more Breast Cancer Trials Podcast Episodes here⁠⁠⁠Follow Breast Cancer Trials on Social Media: Instagram:⁠ ⁠⁠@breastcancertrials⁠⁠⁠  Facebook:⁠ ⁠⁠Breast Cancer Trials⁠⁠⁠ LinkedIn: ⁠⁠⁠Breast Cancer Trials⁠⁠⁠ X: ⁠⁠⁠@BCTrialsANZ⁠⁠⁠Guest: Breast Surgeon, Associate Professor Sanjay Warrier, from SydneyThank you for listening! If you found this episode valuable, please share it with your loved ones and help spread awareness about the importance of tailored breast screening.

Advancing Care for Young Women with Breast CancerYoung women with breast cancer often face unique challenges beyond their diagnosis, including long-term survivorship issues, fertility and family planning concerns, and a higher likelihood of aggressive cancers. But are their treatment pathways keeping up? Dr Belinda Kiely explains the ground-breaking OPTIMA-Young trial, part of the larger PATH-for-Young initiative, exploring how global collaboration could change the future of treatment for younger patients.In this episode, we sit down with Belinda to discuss:(04:14) How does OPTIMA-Young differ from existing treatment approaches?(05:25) Why is it important to have an international collaborative approach?(06:21) How will findings from OPTIMA-Young potentially change the way that we treat young breast cancer patients in the future?Tune in for a deep dive into this important research.⁠⁠Donate to Support Life-Saving Research⁠⁠Like this episode? ⁠⁠Find more Breast Cancer Trials Podcast Episodes here⁠⁠Follow Breast Cancer Trials on Social Media:  Instagram:⁠ ⁠@breastcancertrials⁠⁠  Facebook:⁠ ⁠Breast Cancer Trials⁠⁠ LinkedIn: ⁠⁠Breast Cancer Trials⁠⁠ X: ⁠⁠@BCTrialsANZ⁠⁠Guest: Medical Oncologist Belinda Kiely, from SydneyThank you for listening! If you found this episode valuable, please share it with your loved ones and help spread awareness about the importance of clinical trials research.

Holding It Together: Breast Cancer and the Busy Mum LifeWhen you’re a mum of two young boys, life is full of chaos, and for Belinda, it also became a time of deep uncertainty when, in 2019, she was diagnosed with triple-negative breast cancer. In this episode, we sit down with Belinda to discuss:Navigating a breast cancer diagnosis while raising a young family.The importance of having a community around you to offer support during this time. Why Breast Cancer Trials' research is so important.Tune in for a deep dive into this important research.⁠Donate to Support Life-Saving Research⁠Like this episode? ⁠Find more Breast Cancer Trials Podcast Episodes here⁠Follow Breast Cancer Trials on Social Media:  Instagram:⁠ @breastcancertrials⁠  Facebook:⁠ Breast Cancer Trials⁠ LinkedIn: ⁠Breast Cancer Trials⁠ X: ⁠@BCTrialsANZ⁠Guest: Belinda WardThank you for listening! If you found this episode valuable, please share it with your loved ones and help spread awareness about the importance of breast cancer clinical trials research.

Routine, Resilience, and Research: One Mum's Cancer StoryWhat happens when your life plans are suddenly redrawn by a breast cancer diagnosis? Emily, her husband, and their two children had moved to Australia in 2012 from the UK and was busy building a future for her family when she found herself on a very different path. In this episode, we sit down with Emily to discuss:Navigating breast cancer with a young family. The role that routine and swimming played in helping her cope.The role that Herceptin, a treatment drug brought about by the Breast Cancer Trials HERA trial, played in her treatment.Why breast cancer clinical trials research is so vital.Tune in for a deep dive into this important research.⁠Donate to Support Life-Saving Research⁠Like this episode? ⁠Find more Breast Cancer Trials Podcast Episodes here⁠Follow Breast Cancer Trials on Social Media: Instagram:⁠ @breastcancertrials⁠  Facebook:⁠ Breast Cancer Trials⁠ LinkedIn: ⁠Breast Cancer Trials⁠ X: ⁠@BCTrialsANZ⁠Guest: Emily Allard Thank you for listening! If you found this episode valuable, please share it with your loved ones and help spread awareness about breast cancer clinical trials research.

The Village Effect: Why Community Matters During Cancer TreatmentFor Sarah, motherhood was already a full-time job — between nippers, football, and everything in between. When she was diagnosed with breast cancer, she found herself navigating treatment while parenting young children and holding her family together through the uncertainty.In this episode, we sit down with Sarah to discuss:The lead-up to her shock diagnosis.Balancing breast cancer treatment and motherhood.The importance of having a strong support system in place during treatment. Why Breast Cancer Trials' research is so important. Tune in for a deep dive into this important research.⁠Donate to Support Life-Saving Research⁠Like this episode? ⁠Find more Breast Cancer Trials Podcast Episodes here⁠Follow Breast Cancer Trials on Social Media:  Instagram:⁠ @breastcancertrials⁠  Facebook:⁠ Breast Cancer Trials⁠ LinkedIn: ⁠Breast Cancer Trials⁠ X: ⁠@BCTrialsANZ⁠Guest: Sarah Withyman Thank you for listening! If you found this episode valuable, please share it with your loved ones and help spread awareness about breast cancer clinical trials research.

Virtual Reality Meets Radiation: A New Era in Patient CoachingKathleene Dower is a Radiation Therapist and 2025 Clinical Fellow with Breast Cancer Trials. Her project is about piloting virtual reality (VR) coaching and education for deep inspiration breath hold, a breathing technique used during radiation therapy to move the heart away from radiation and protect it from damage. This study will explore whether VR coaching and education can help patients learn this technique more effectively. In this episode, we sit down with Kathleene to discuss:An overview of Deep Inspiration Breath Hold (DIBH), and how to effectively do this.How the VR coaching program works. The benefits of using BR compared to traditional coaching methods for DIBH.Next steps after this pilot study.Tune in for a deep dive into this important research.⁠Donate to Support Life-Saving Research⁠Like this episode? ⁠Find more Breast Cancer Trials Podcast Episodes here⁠Follow Breast Cancer Trials on Social Media:  Instagram:⁠ @breastcancertrials⁠  Facebook:⁠ Breast Cancer Trials⁠ LinkedIn: ⁠Breast Cancer Trials⁠ X: ⁠@BCTrialsANZ⁠Guest: Kathleene Dower from Lismore Base HospitalThank you for listening! If you found this episode valuable, please share it with your loved ones and help spread awareness about breast cancer clinical trials research.

From IVF to Breast Cancer: Navigating a Diagnosis in Early MotherhoodRebecca Pickering is a devoted mum to Daphne and Dorothy and wife to Matt. She loves spending quality time with her family and exploring the beauty of her hometown, Mildura. Rebecca’s journey to motherhood included a series of IVF treatments before welcoming her two daughters. Not long after their birth, she began noticing changes in her breasts, and after visiting her doctor for a check-up, she was unfortunately diagnosed with breast cancer. In this episode, we sit down with Rebecca to discuss:Her breast cancer diagnosis.Navigating breast cancer with a young family.Participating in the OLIO clinical trialRemote monitoring during treatment. Tune in for a deep dive into this important conversation.⁠Donate to Support Life-Saving Research⁠Like this episode? ⁠Find more Breast Cancer Trials Podcast Episodes here⁠Follow Breast Cancer Trials on Social Media:  Instagram:⁠ @breastcancertrials⁠  Facebook:⁠ Breast Cancer Trials⁠ LinkedIn: ⁠Breast Cancer Trials⁠ X: ⁠@BCTrialsANZ⁠Guest: Mrs Rebecca PickeringThank you for listening! If you found this episode valuable, please share it with your loved ones and help spread awareness about breast cancer clinical trials research.

Beyond the Plate: Rebuilding Healthy Habits After Breast Cancer Lifestyle interventions such as diet and exercise have been shown to have positive impacts on clinical outcomes, including tolerance to chemotherapy, fatigue, weight maintenance, and reduced risk of cancer recurrence. However, no one intervention fits all. Maintaining healthy lifestyle activities can be challenging for some, and the reasons for non-adherence vary.In this episode, we sit down with Cindy Tan from the Concord Hospital in Sydney to discuss:The role of diet and exercise in breast cancer treatment. Barriers and enablers of breast cancer survivors to join a lifestyle intervention.The future steps in this area of research.Tune in for a deep dive into this important research.⁠Donate to Support Life-Saving Research⁠Like this episode? ⁠Find more Breast Cancer Trials Podcast Episodes here⁠Follow Breast Cancer Trials on Social Media:  Instagram:⁠ @breastcancertrials⁠  Facebook:⁠ Breast Cancer Trials⁠ LinkedIn: ⁠Breast Cancer Trials⁠ X: ⁠@BCTrialsANZ⁠Guest: Dr Cindy Tan, Concord Hospital in SydneyThank you for listening! If you found this episode valuable, please share it with your loved ones and help spread awareness about breast cancer clinical trials research.

Revolutionising Radiotherapy: The ORNATE Study and the Future of Breast Cancer Treatment Dr Metz is a radiation oncologist and 2025 clinical fellow with Breast Cancer Trials. Her project, optimising radiotherapy in the neoadjuvant therapy era, also known as ORNATE, aims to refine radiotherapy for breast cancer patients receiving chemotherapy before surgery.In this episode, we sit down with Dr Gabrielle Metz from the Royal North Shore Hospital to discuss: What the database is, and its role in breast cancer treatment. How researchers will explore whether radiation doses can be safely reduced in certain patients.Options for less invasive lymph node treatments.The future of patient outcomes in this space. Tune in for a deep dive into this important research.⁠⁠Donate to Support Life-Saving Research⁠⁠ Like this episode? ⁠⁠Find more Breast Cancer Trials Podcast Episodes here⁠⁠Follow Breast Cancer Trials on Social Media:  Instagram:⁠ ⁠@breastcancertrials⁠⁠  Facebook:⁠ ⁠Breast Cancer Trials⁠⁠ LinkedIn: ⁠⁠Breast Cancer Trials⁠⁠ X: ⁠⁠@BCTrialsANZ⁠⁠Guest: Dr Gabrielle Metz, Radiation Oncologist Thank you for listening! If you found this episode valuable, please share it with your loved ones and help spread awareness about the importance of breast cancer clinical trials research.

Understanding Antibody-Drug Conjugates (ADCs) in Metastatic Breast Cancer: Breakthroughs, Challenges, and the Future of Targeted TherapyADCs are a breakthrough in targeted chemotherapy for metastatic breast cancer. While ADCs like trastuzumab deruxtecan (T-DXd) offer new hope, challenges like resistance and various side effects still remain, and can therefore limit their clinical use. In this episode, we sit down with Dr Michelle Li from the Peter MacCallum Cancer Centre to discuss: The current landscape of metastatic breast cancer.The role of ADCs in the treatment of metastatic breast cancer.What makes certain treatment options more effective than others in the context of metastatic disease?Future steps in this area of research, and the role of international collaboration.Tune in for a deep dive into this important research.⁠Donate to Support Life-Saving Research⁠ Like this episode? ⁠Find more Breast Cancer Trials Podcast Episodes here⁠Follow Breast Cancer Trials on Social Media:  Instagram:⁠ @breastcancertrials⁠  Facebook:⁠ Breast Cancer Trials⁠ LinkedIn: ⁠Breast Cancer Trials⁠ X: ⁠@BCTrialsANZ⁠Guest: Dr Michelle Li, Medical OncologistThank you for listening! If you found this episode valuable, please share it with your loved ones and help spread awareness about the importance of breast cancer clinical trials research.