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Study shows intermittent fasting helps Type 2 diabetics manage weight and blood sugar levels. Participants who ate within an 8-hour window lost more weight in 6 months than those who reduced calorie intake by 25%. No adverse events or blood sugar issues reported. #TRE #timerestrictedeating #diabetes Pavlou V, Cienfuegos S, Lin S, et al. Effect of Time-Restricted Eating on Weight Loss in Adults With Type 2 Diabetes: A Randomized Clinical Trial. JAMA Netw Open. 2023;6(10):e2339337. doi:10.1001/jamanetworkopen.2023.39337   Alchepharma,Ralph Turchiano,citation,research,study,time-restricted eating,type 2 diabetes,intermittent fasting,type 2 diabetes diet breakthrough,reverse diabetes with time-restricted eating,time-restricted eating weight loss results,time-restricted eating blood sugar control,time-restricted eating safety,intermittent fasting for beginners,time-restricted eating tips and tricks,intermittent fasting for weight loss,8-hour time-restricted eating for type 2 diabetes --- Support this podcast: https://podcasters.spotify.com/pod/show/ralph-turchiano/support

Study shows intermittent fasting helps Type 2 diabetics manage weight and blood sugar levels. Participants who ate within an 8-hour window lost more weight in 6 months than those who reduced calorie intake by 25%. No adverse events or blood sugar issues reported. #TRE #timerestrictedeating #diabetes Pavlou V, Cienfuegos S, Lin S, et al. Effect of Time-Restricted Eating on Weight Loss in Adults With Type 2 Diabetes: A Randomized Clinical Trial. JAMA Netw Open. 2023;6(10):e2339337. doi:10.1001/jamanetworkopen.2023.39337 Alchepharma,Ralph Turchiano,citation,research,study,time-restricted eating,type 2 diabetes,intermittent fasting,type 2 diabetes diet breakthrough,reverse diabetes with time-restricted eating,time-restricted eating weight loss results,time-restricted eating blood sugar control,time-restricted eating safety,intermittent fasting for beginners,time-restricted eating tips and tricks,intermittent fasting for weight loss,8-hour time-restricted eating for type 2 diabetes --- Support this podcast: https://podcasters.spotify.com/pod/show/ralph-turchiano/support

New research has revealed a potentially important role ginger supplements can play in controlling inflammation for people living with autoimmune diseases. The research focused on studying the impact of ginger supplementation on a type of white blood cell called the neutrophil. The study was especially interested in neutrophil extracellular trap (NET) formation, also known as NETosis, and what it may mean for controlling inflammation. #ginger #autoimmune #gingerol Ramadan A. Ali, Valerie C. Minarchick, Miela Zahavi, Christine E. Rysenga, Kristin A. Sturm, Claire K. Hoy, Cyrus Sarosh, Jason S. Knight, M. Kristen Demoruelle. Ginger intake suppresses neutrophil extracellular trap formation in autoimmune mice and healthy humans. JCI Insight, 2023; 8 (18) DOI: 10.1172/jci.insight.172011 --- Support this podcast: https://podcasters.spotify.com/pod/show/ralph-turchiano/support

Ginger consumption and possible autoimmune benefits Ep. 1162 NOV 2023 New research has revealed a potentially important role ginger supplements can play in controlling inflammation for people living with autoimmune diseases. The research focused on studying the impact of ginger supplementation on a type of white blood cell called the neutrophil. The study was especially interested in neutrophil extracellular trap (NET) formation, also known as NETosis, and what it may mean for controlling inflammation. #ginger #autoimmune #gingerol Ramadan A. Ali, Valerie C. Minarchick, Miela Zahavi, Christine E. Rysenga, Kristin A. Sturm, Claire K. Hoy, Cyrus Sarosh, Jason S. Knight, M. Kristen Demoruelle. Ginger intake suppresses neutrophil extracellular trap formation in autoimmune mice and healthy humans. JCI Insight, 2023; 8 (18) DOI: 10.1172/jci.insight.172011 --- Support this podcast: https://podcasters.spotify.com/pod/show/ralph-turchiano/support

Establishing the relationship between inflammatory markers like IL-6 and CRP [and vitamin B12 levels] could have direct clinical relevance and open doors to novel therapeutic strategies. #B12 #Inflammation #Homocysteine Domínguez-López, I., Kovatcheva, M., Casas, R., Toledo, E., Fitó, M., Ros, E., Estruch, R., Serrano, M., & Lamuela-Raventós, R. M. Higher circulating vitamin B12 is associated with lower levels of inflammatory markers in individuals at high cardiovascular risk and in naturally aged mice. Journal of the Science of Food and Agriculture. https://doi.org/10.1002/jsfa.12976 B12, Homocysteine, Inflammation, interlukin-6, CRP, IL-6 C reactive protein, diabetes, cancer, atherosclerosis, B12 deficiency --- Support this podcast: https://podcasters.spotify.com/pod/show/ralph-turchiano/support

Establishing the relationship between inflammatory markers like IL-6 and CRP [and vitamin B12 levels] could have direct clinical relevance and open doors to novel therapeutic strategies.’ #B12 #Inflammation #Homocysteine Domínguez-López, I., Kovatcheva, M., Casas, R., Toledo, E., Fitó, M., Ros, E., Estruch, R., Serrano, M., & Lamuela-Raventós, R. M. Higher circulating vitamin B12 is associated with lower levels of inflammatory markers in individuals at high cardiovascular risk and in naturally aged mice. Journal of the Science of Food and Agriculture. https://doi.org/10.1002/jsfa.12976 B12, Homocysteine, Inflammation, interlukin-6, CRP, IL-6 C reactive protein, diabetes, cancer, atherosclerosis, B12 deficiency --- Support this podcast: https://podcasters.spotify.com/pod/show/ralph-turchiano/support

It can increase the rate of protein synthesis within muscle cells and inhibit protein degradation processes [53]. This allows muscle cells to more effectively synthesize new proteins and maintain muscle mass. Additionally, Urolithin A can improve muscle endurance and exercise performance by promoting mitochondrial function and muscle energy metabolism [66]. This may lead to longer and more intense training sessions, further promoting muscle hypertrophy and the maintenance of muscle mass. #urolitinA #strength #endurance Zhao, H., Song, G., Zhu, H., Qian, H., Pan, X., Song, X., Xie, Y., & Liu, C. (2023). Pharmacological Effects of Urolithin A and Its Role in Muscle Health and Performance: Current Knowledge and Prospects. Nutrients, 15(20), 4441. https://doi.org/10.3390/nu15204441 Urolithin a, Ellagitannins, muscle mass, strength, speed, endurance, energy, contraction speed, atp, Enhanced Muscle Function, Delaying Muscle Fatigue, Muscle Atrophy, Antioxidant Defense, Mitochondrial Dysfunction, Inflammatory Conditions, Oxidative Stress, --- Support this podcast: https://podcasters.spotify.com/pod/show/ralph-turchiano/support

It can increase the rate of protein synthesis within muscle cells and inhibit protein degradation processes [53]. This allows muscle cells to more effectively synthesize new proteins and maintain muscle mass. Additionally, Urolithin A can improve muscle endurance and exercise performance by promoting mitochondrial function and muscle energy metabolism [66]. This may lead to longer and more intense training sessions, further promoting muscle hypertrophy and the maintenance of muscle mass. #urolitinA #strength #endurance Zhao, H., Song, G., Zhu, H., Qian, H., Pan, X., Song, X., Xie, Y., & Liu, C. (2023). Pharmacological Effects of Urolithin A and Its Role in Muscle Health and Performance: Current Knowledge and Prospects. Nutrients, 15(20), 4441. https://doi.org/10.3390/nu15204441 Urolithin a, Ellagitannins, muscle mass, strength, speed, endurance, energy, contraction speed, atp, Enhanced Muscle Function, Delaying Muscle Fatigue, Muscle Atrophy, Antioxidant Defense, Mitochondrial Dysfunction, Inflammatory Conditions, Oxidative Stress, --- Support this podcast: https://podcasters.spotify.com/pod/show/ralph-turchiano/support

Dark tea may Dramatically HELP control blood sugar to reduce diabetes risk Episode 1158 OCT 2023 The study, by researchers from the University of Adelaide in Australia and Southeast University in China, found that compared with never tea drinkers, daily consumers (never, occasionally, often and every day) ) of dark tea had 53% lower risk for prediabetes and 47% reduced risk for type 2 diabetes, even after taking into account established risk factors known to drive the risk for diabetes, including age, gender, ethnicity, body mass index (BMI), average arterial blood pressure, fasting plasma glucose, cholesterol, alcohol intake, smoking status, family history of diabetes and regular exercise. #darktea #bloodsugar #diabetes Poster presentation 329 at the annual meeting of the European Association for the Study of Diabetes (EASD), Tea consumption is associated with increased urinary glucose excretion, improved insulin resistance and reduced risk of dysglycaemia, in Chinese community-dwelling adults T. Li, M. Sang, J. Wang, Z. Sun, C. Xie, C. Rayner, M. Horowitz, S. Qiu, T. Wu, Australia, China --- Support this podcast: https://podcasters.spotify.com/pod/show/ralph-turchiano/support

The study, by researchers from the University of Adelaide in Australia and Southeast University in China, found that compared with never tea drinkers, daily consumers (never, occasionally, often and every day) ) of dark tea had 53% lower risk for prediabetes and 47% reduced risk for type 2 diabetes, even after taking into account established risk factors known to drive the risk for diabetes, including age, gender, ethnicity, body mass index (BMI), average arterial blood pressure, fasting plasma glucose, cholesterol, alcohol intake, smoking status, family history of diabetes and regular exercise. #darktea #bloodsugar #diabetes Poster presentation 329 at the annual meeting of the European Association for the Study of Diabetes (EASD), Tea consumption is associated with increased urinary glucose excretion, improved insulin resistance and reduced risk of dysglycaemia, in Chinese community-dwelling adults T. Li, M. Sang, J. Wang, Z. Sun, C. Xie, C. Rayner, M. Horowitz, S. Qiu, T. Wu, Australia, China --- Support this podcast: https://podcasters.spotify.com/pod/show/ralph-turchiano/support

Recent studies have reported the beneficial effects of KRG extract— a traditional herbal medicine— in treating neuroinflammation. Although, it has been traditionally used to treat a number of ailments, KRG is now finding use in diseases of the modern day, such as cardiovascular diseases, cancer, and Alzheimer’s disease. Previous research on rodents has demonstrated that KRG can relieve addiction against psychoactive agents. However, not much is known about the its effects on alcohol-induced addictive responses and cognitive impariment. #koreanredginseng #addiction #neuroinflammation Kim, H. J., Lee, M. Y., Kim, G. R., Lee, H. J., Sayson, L. V., Ortiz, D. M. D., Cheong, J. H., & Kim, M. (2023). Korean Red Ginseng extract attenuates alcohol-induced addictive responses and cognitive impairments by alleviating neuroinflammation. Journal of Ginseng Research, 47(4), 583-592. https://doi.org/10.1016/j.jgr.2023.02.003 --- Support this podcast: https://podcasters.spotify.com/pod/show/ralph-turchiano/support

Recent studies have reported the beneficial effects of KRG extract— a traditional herbal medicine— in treating neuroinflammation. Although, it has been traditionally used to treat a number of ailments, KRG is now finding use in diseases of the modern day, such as cardiovascular diseases, cancer, and Alzheimer’s disease. Previous research on rodents has demonstrated that KRG can relieve addiction against psychoactive agents. However, not much is known about the its effects on alcohol-induced addictive responses and cognitive impariment. #koreanredginseng #addiction #neuroinflammation Kim, H. J., Lee, M. Y., Kim, G. R., Lee, H. J., Sayson, L. V., Ortiz, D. M. D., Cheong, J. H., & Kim, M. (2023). Korean Red Ginseng extract attenuates alcohol-induced addictive responses and cognitive impairments by alleviating neuroinflammation. Journal of Ginseng Research, 47(4), 583-592. https://doi.org/10.1016/j.jgr.2023.02.003 --- Support this podcast: https://podcasters.spotify.com/pod/show/ralph-turchiano/support

Implications for the Future- In essence, this groundbreaking research indicates that by encouraging the recycling of mitochondria using Urolithin A, it is possible to reverse the aging process within the hematopoietic and immune systems. These findings hold immense promise for the development of interventions targeted at addressing age-related health conditions in older individuals and pave the way for envisioning clinical trials. #urolithinA #ellagic #ellagitannins Girotra, M., Chiang, Y., Charmoy, M., Ginefra, P., Hope, H. C., Bataclan, C., Yu, Y., Schyrr, F., Franco, F., Geiger, H., Cherix, S., Ho, P., Naveiras, O., Auwerx, J., Held, W., & Vannini, N. (2023). Induction of mitochondrial recycling reverts age-associated decline of the hematopoietic and immune systems. Nature Aging, 1-10. https://doi.org/10.1038/s43587-023-00473-3 An, L., Lu, Q., Wang, K., & Wang, Y. (2023). Urolithins: A Prospective Alternative against Brain Aging. Nutrients, 15(18), 3884. https://doi.org/10.3390/nu15183884 --- Support this podcast: https://podcasters.spotify.com/pod/show/ralph-turchiano/support

Implications for the Future- In essence, this groundbreaking research indicates that by encouraging the recycling of mitochondria using Urolithin A, it is possible to reverse the aging process within the hematopoietic and immune systems. These findings hold immense promise for the development of interventions targeted at addressing age-related health conditions in older individuals and pave the way for envisioning clinical trials. #urolithinA #ellagic #ellagitannins Girotra, M., Chiang, Y., Charmoy, M., Ginefra, P., Hope, H. C., Bataclan, C., Yu, Y., Schyrr, F., Franco, F., Geiger, H., Cherix, S., Ho, P., Naveiras, O., Auwerx, J., Held, W., & Vannini, N. (2023). Induction of mitochondrial recycling reverts age-associated decline of the hematopoietic and immune systems. Nature Aging, 1-10. https://doi.org/10.1038/s43587-023-00473-3   An, L., Lu, Q., Wang, K., & Wang, Y. (2023). Urolithins: A Prospective Alternative against Brain Aging. Nutrients, 15(18), 3884. https://doi.org/10.3390/nu15183884 --- Support this podcast: https://podcasters.spotify.com/pod/show/ralph-turchiano/support

Peppermint Oil Endurance Booster Peppermint essential oil, with its active ingredients, is believed to reduce oxidative stress and inflammation induced by exercise and thus relieve exercise-induced fatigue and improve exercise performance #peppermint #endurance #exercise Zhang, W., Shi, R., Gao, T., Hu, Y., Zhou, J., Li, C., Wang, P., Yang, H., Xing, W., Dong, L., & Gao, F. (2023). Repeated Inhalation of Peppermint Essential Oil Improves Exercise Performance in Endurance-Trained Rats. Nutrients, 15(11), 2480. https://doi.org/10.3390/nu15112480 --- Support this podcast: https://podcasters.spotify.com/pod/show/ralph-turchiano/support

Peppermint essential oil, with its active ingredients, is believed to reduce oxidative stress and inflammation induced by exercise and thus relieve exercise-induced fatigue and improve exercise performance #peppermint #endurance #exercise Zhang, W., Shi, R., Gao, T., Hu, Y., Zhou, J., Li, C., Wang, P., Yang, H., Xing, W., Dong, L., & Gao, F. (2023). Repeated Inhalation of Peppermint Essential Oil Improves Exercise Performance in Endurance-Trained Rats. Nutrients, 15(11), 2480. https://doi.org/10.3390/nu15112480 --- Support this podcast: https://podcasters.spotify.com/pod/show/ralph-turchiano/support

The active ingredients of ginseng mainly contribute to aging delay through the following mechanisms: (1) the increase in the expression of antioxidant enzymes to achieve a balance between intracellular oxidation and antioxidation, the mitigation of excessive production of ROS, and the reduction in endogenous DNA damage, which prevent cell cycle arrest and delay aging; and (2) the regulation of the activities of DNA glycosylase and sirtuins in the process of DNA damage repair to ensure that the DNA repair pathway can accurately repair DNA damage caused by various factors associated with aging. #ginseng #aging #microbiota Su, J., Su, Q., Hu, S., Ruan, X., & Ouyang, S. (2023). Research Progress on the Anti-Aging Potential of the Active Components of Ginseng. Nutrients, 15(15), 3286. https://doi.org/10.3390/nu15153286 --- Support this podcast: https://podcasters.spotify.com/pod/show/ralph-turchiano/support

The active ingredients of ginseng mainly contribute to aging delay through the following mechanisms: (1) the increase in the expression of antioxidant enzymes to achieve a balance between intracellular oxidation and antioxidation, the mitigation of excessive production of ROS, and the reduction in endogenous DNA damage, which prevent cell cycle arrest and delay aging; and (2) the regulation of the activities of DNA glycosylase and sirtuins in the process of DNA damage repair to ensure that the DNA repair pathway can accurately repair DNA damage caused by various factors associated with aging. #ginseng #aging #microbiota Su, J., Su, Q., Hu, S., Ruan, X., & Ouyang, S. (2023). Research Progress on the Anti-Aging Potential of the Active Components of Ginseng. Nutrients, 15(15), 3286. https://doi.org/10.3390/nu15153286 --- Support this podcast: https://podcasters.spotify.com/pod/show/ralph-turchiano/support

226% increase in Cognition with Essential Oils Show 1150 AUG 2023 When a fragrance wafted through the bedrooms of older adults for two hours every night for six months, memories skyrocketed. Participants in this study by University of California, Irvine neuroscientists reaped a 226% increase in cognitive capacity compared to the control group. The researchers say the finding transforms the long-known tie between smell and memory into an easy, non-invasive technique for strengthening memory and potentially deterring dementia. #cognition #aromatherapy #olfactory Woo, C. C., Miranda, B., Sathishkumar, M., Yassa, M. A., & Leon, M. (2023). Overnight olfactory enrichment using an odorant diffuser improves memory and modifies the uncinate fasciculus in older adults. Frontiers in Neuroscience, 17, 1200448. https://doi.org/10.3389/fnins.2023.1200448 Cognition, memory, scent, essential oils, verbal learning, dementia, aromatherapy , uncinate fasciculus, rose, orange, eucalyptus, lemon, peppermint, rosemary, lavender, gray matter, white matter, olfactory enrichment, olfactory stimulation, olfactory ability, Alzheimer’s --- Support this podcast: https://podcasters.spotify.com/pod/show/ralph-turchiano/support

226% increase in Cognition with Essential Oils Show 1150 AUG 2023 When a fragrance wafted through the bedrooms of older adults for two hours every night for six months, memories skyrocketed. Participants in this study by University of California, Irvine neuroscientists reaped a 226% increase in cognitive capacity compared to the control group. The researchers say the finding transforms the long-known tie between smell and memory into an easy, non-invasive technique for strengthening memory and potentially deterring dementia. #cognition #aromatherapy #olfactory Woo, C. C., Miranda, B., Sathishkumar, M., Yassa, M. A., & Leon, M. (2023). Overnight olfactory enrichment using an odorant diffuser improves memory and modifies the uncinate fasciculus in older adults. Frontiers in Neuroscience, 17, 1200448. https://doi.org/10.3389/fnins.2023.1200448 Cognition, memory, scent, essential oils, verbal learning, dementia, aromatherapy , uncinate fasciculus, rose, orange, eucalyptus, lemon, peppermint, rosemary, lavender, gray matter, white matter, olfactory enrichment, olfactory stimulation, olfactory ability, Alzheimer’s --- Support this podcast: https://podcasters.spotify.com/pod/show/ralph-turchiano/support