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Grow Everything Biotech Podcast
Grow Everything Biotech Podcast
Author: Messaginglab
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Grow Everything explores the world of biology as technology. Hosts Erum Khan and Karl Schmieder interview leaders and influencers biologizing industries with tools like synthetic biology, precision fermentation, bioprospecting, and more. These companies make biomaterials from waste, cosmetics that restore healthy hair and skin, and delicious cultivated foods in a bioreactor and so much more. Join us as we discuss the latest and greatest across biotech, engineered biology, entrepreneurship, and culture and how this transition is solving healthcare and climate change challenges.
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Damien Perriman, Chief Commercial Officer of eXoZymes and the commercial lead behind the NCTx spinout, breaks down why cell-free biomanufacturing changes the rules for scaling nature’s rare molecules. Damien explains why the team spun NCTX out as a separate commercial vehicle, what it means to successfully transfer a process to a partner manufacturer (including a milestone Cayman validation), and why NCT (n-trans-caffeoyl tyramine), a trace compound found in peppercorns and hemp seed husks, has drawn so much attention as the only known agonist of HNF4A, a metabolic “switch” tied to mitochondrial function. The conversation also covers the logic behind launching first in supplements, how to build credibility in a crowded category through safety and product consistency, how regulatory timelines shape strategy, and why industrial biotech needs to move from platform-first stories to molecule-led business cases that match real market demand.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?Learn more at www.messaginglab.com/groweverythingChapters:(00:00:00) Welcome, introductions, and why tech transfer matters(00:02:10) Why eXoZymes spun out NCTX to commercialize faster(00:03:30) Cayman scale-up milestone: 99% conversion and 99.6% purity(00:05:20) What the Cayman validation proves for product delivery and partners(00:08:10) Why launch NCT in supplements first, and what GRAS enables(00:10:00) Building credibility in supplements: safety, purity, and consistency(00:12:05) What HNF4A is, and why NCT is the only known agonist(00:14:30) What’s next: more human use studies, dose regimens, and GLP-1 adjacencies(00:16:00) NCT vs GLP-1s: “metabolic restoration” and where it might fit(00:18:10) “Natural” vs safe and effective: what really matters(00:21:00) Examples of trace natural molecules scaled for human use(00:22:30) GRAS + FDA timelines: how they’re navigating regulatory reality(00:26:00) The Molecule Manifesto: why industrial biotech needs molecule-led business cases(00:31:00) How eXoZymes chooses what to work on (idea management system)(00:33:00) Vision: what success looks like in 5–10 years(00:35:00) Quickfire: NCT in ice cream, NCT as “WALL-E,” and other rapid takes(00:38:10) What people misunderstand about cell-free biomanufacturing(00:40:00) Wrap-up + post-episode reflectionLinks and Resources:eXoZymesInterview: Cayman Chemical validates eXoZymes' technology and scalabilityeXoZymes’ Cell-Free Biomanufacturing Platform Gets Positive Feedback from Cayman ChemicaleXoZymes on LinkedInDamien Perriman - new CCO129. No Cells? No Problem! eXoZymes' Michael Heltzen on the Future of Microbe-Free Biotech29. Gut Check with Stephanie Culler: Persephone’s Quest for Microbiome Breakthroughs170. There's a Bug for That: Sophia Xu on CarbonBridge's Notebook Bioreactors166. The Great Reformulation: Joshua Lachter Rethinks How We Make Everything at ScaleTopics Covered:cell-free biomanufacturing, industrial biotech, NCTx, HNF4A, metabolic switch, tech transfer, CDMO, supplements vs pharma, GRAS, purity and consistencyHave a question or comment? Message us here:Text or Call (804) 505-5553Instagram / Twitter / LinkedIn / Youtube / Grow EverythingMusic by: Nihilore Production by: Amplafy Media
Mari Granstrom, founder and “chief executive activist” of Origin By Ocean, joins the Grow Everything podcast to explain how massive seaweed blooms, driven by nutrient pollution and eutrophication, can become a regenerative feedstock for bio-based and biodegradable chemicals. Mari shares how a career in industrial biochemistry, plus years of scuba diving and growing up near the polluted Baltic Sea, shaped their mission to transform invasive sargassum into high-performance ingredients that can replace many oil-derived inputs in everyday products. The conversation covers the scale of the sargassum problem across the Caribbean and Gulf of Mexico, how Origin By Ocean processes seaweed into “white powders” customers can use in cosmetics and nutraceuticals, and why the future of climate entrepreneurship needs diversity, integrity, and business models that restore ecosystems instead of extracting from them.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?Learn more at www.messaginglab.com/groweverythingChapters:(00:00:00) Seaweed is the oil we never used(00:01:00) Karl’s Hidden Brain live show story + talking to strangers(00:03:00) Spring break travel + staying plugged into biotech(00:04:05) Pfizer Oscars ad: what “breakthrough” messaging gets right(00:08:15) Echo Biotech + NYC’s biotech network, from biomaterials to investing(00:11:10) Meet Mari Granstrom and Origin By Ocean (how they met at Climate Week)(00:14:00) Mari’s path: biochemical expertise inside big chemical companies(00:16:25) Eutrophication 101 + spotting seaweed blooms as future biomass(00:19:20) The sargassum crisis: 40–60M tons/year in the Caribbean + Gulf(00:21:00) Is this just a Gulf issue? Baltic Sea vs “real oceans”(00:23:00) Turning research into a real biorefinery business(00:25:00) “Chief executive activist”: science, entrepreneurship, advocacy as one role(00:28:05) How seaweed can replace oil-derived functionality in everyday products(00:30:10) Regenerative value chains vs ESG (doing less harm vs net-positive)(00:33:00) Why diversity (backgrounds, not just demographics) drives better solutions(00:34:00) Future-casting: where marine biomass will (and won’t) make sense(00:37:00) Quickfire: ocean’s passive-aggressive text, algae blooms, nudibranchs(00:40:00) Demo products: cosmetics, hair growth, makeup + showing customers potential(00:41:00) Wrap-up reflections (seaweed as feedstock, alternate history)Links and Resources:Mari Granstorm episode linksSynBioBeta Pass - Discount code: Grow Everything Topics Covered:fermentation, biomanufacturing, yeast, Lallemand, enzymes, biofuels, xylose, Saccharomyces cerevisiae, genomics, synthetic biologyHave a question or comment? Message us here:Text or Call (804) 505-5553Instagram / Twitter / LinkedIn / Youtube / Grow EverythingMusic by: Nihilore Production by: Amplafy Media
Kevin Wegner, VP of R&D at Lallemand, joins Karl and Erum to share three decades of wisdom from the frontlines of industrial fermentation. From his gateway into the industry through homebrewing beer to leading global teams that deliver high-value microbial products at billion-gallon scale, Kevin reveals why a 1% improvement in ethanol yield translates to massive economic value, how his team engineered yeast strains that produce both enzymes and ethanol simultaneously, and why scaling from large to even larger bioreactors requires solving genetic and environmental puzzles simultaneously. The conversation explores Lallemand's century-long evolution from baker's yeast to cutting-edge synthetic biology, the untapped potential of xylose and complex sugars for expanding biomanufacturing feedstocks, and Kevin's vision for anaerobic fermentation, digital twins of cells, and biodegradable materials with perfectly tuned lifecycles. Whether you're fascinated by the microbial diversity hiding in America's public lands, curious about why sour beer yeast is a game-changer for Brooklyn craft brewers, or wondering how fermentation could revolutionize water treatment and replace single-use plastics, this episode unpacks the science, strategy, and scale needed to grow everything.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?Learn more at www.messaginglab.com/groweverythingChapters:(00:00:00) - Flux capacitor, compost heat, and New York City garbage as fuel(00:03:10) - AI regulation and “synthetic beings”(00:06:00) - Shoutouts and recent hangs (Paul Shapiro, Superorganism, The Wooly)(00:09:40) - Longevity + a sauna networking event(00:13:30) - Advanced Biotech for Sustainability report + introducing Kevin Wegner(00:15:50) - Kevin’s origin story: chemistry, microbiology, and homebrewing beer(00:17:00) - Early lessons in large-scale fermentation and scale-up realities(00:22:00) - What Lallemand does today and who they serve(00:33:40) - How legacy fermentation drives innovation (including sour beer yeast)(00:37:30) - America’s Living Library Act, Molecule Manifesto, digital twins, and “anaerobic everything”(00:46:40) - Quickfire round + plastics moonshot(00:49:30) - Wrap-up and upcoming events (DC Climate Week, SynBioBeta)Links and Resources:LallemandLallemand Patent ApprovalNovel Yeast- Mascoma, Lallemand Jointly Marketing the New ProductSynBioBeta Pass - Discount code: Grow Everything Topics Covered:fermentation, biomanufacturing, yeast, Lallemand, enzymes, biofuels, xylose, Saccharomyces cerevisiae, genomics, synthetic biologyHave a question or comment? Message us here:Text or Call (804) 505-5553Instagram / Twitter / LinkedIn / Youtube / Grow EverythingMusic by: Nihilore Production by: Amplafy Media
What if the oldest miners on Earth weren't humans at all—but microbes that have been extracting metals for billions of years? In this episode, Karl and Erum sit down with Liz Dennett, founder and CEO of Endolith, who's deploying extremophile microbial communities to unlock up to 1.9x more copper from existing mine heaps at industrial mining sites across the US. Liz shares her journey from growing up in resource-rich Alaska to pioneering bio-leaching technology that's tackling a critical challenge: we need more copper between now and 2050 than humanity has produced in its entire history—and every data center, EV, and AI query depends on it. But here's what makes this conversation different: Liz isn't trying to disrupt mining, she's working with it, bringing "purple-haired PhD energy" to one of the world's most conservative industries through safety-first culture, collaboration over competition, and under-promising, over-delivering results. This episode reveals why biology might be our best tool for responsible resource stewardship and what it really takes to bring breakthrough biotechnology into legacy industrial systems—plus, the copper oxidation series on Liz's nails.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?Learn more at www.messaginglab.com/groweverythingChapters:(00:00:00) - Welcome to the Show: Microbes, Mining, and the Copper Crisis(00:01:53) - The PowerPoint-Google Slides Software Saga(00:03:47) - Meeting Clients In Person: Building Deeper Connections(00:05:05) - Erum's Panel Experience and the HairDAO Moment(00:06:56) - Mining, Microbes, and Copper in the Human Body(00:08:59) - Why Copper Matters for AI and Electrification(00:11:00) - Introducing Liz Dennett: From Alaska to Endolith(00:12:43) - Growing Up in Alaska: Natural Resources as Lived Reality(00:14:00) - The Moment Biology Met Mining(00:15:00) - What is Heap Leaching? Visualizing the Process(00:17:00) - Recovery Rates and Why 10% More Copper is Monumental(00:18:00) - Biology's Surprises: Communities Over Single Organisms(00:19:43) - Extremophiles: Microbes That Love Sulfuric Acid(00:21:00) - Dirty Biology: Engineering Control vs. Biological Adaptability(00:23:00) - Building Trust in a Conservative Industry(00:25:00) - Culture at Endolith: Safety, Feedback, and Snacks(00:27:00) - Validation Work and Customer-Specific Testing(00:28:00) - How Data, Biology, and Infrastructure Shape Resource Thinking(00:30:00) - The Copper Crisis: More Needed by 2050 Than Ever Before(00:33:00) - When Does Biology Work? Redox Reactions and Metal Recovery(00:34:00) - GMOs vs. Wild Type: The Labradoodle Analogy(00:36:00) - Bio-Leaching Evolved: Not Just One Microbe, A Full System(00:38:00) - Collaborating with Rio Tinto Nuton and Gunnison Copper(00:40:00) - Force Multipliers, Not Mine Operators(00:41:00) - The Copper Oxidation Series on Liz's Nails(00:42:00) - The 10-Year Vision: Biology as a Standard Mining Layer(00:44:00) - Quick Fire Questions: Wilderness vs. Mine Site, Copper vs. Lithium(00:45:00) - The Unwavering Playlist and Fundraising Energy(00:47:00) - Wrap-Up and Final Thoughts on Collaboration and the Energy TransitionLinks and Resources:Links and resources DocSynBioBeta Pass - Discount code: Grow Everything Topics Covered:biomining, Copper, mining, microbes, bioleaching, heap leach, extremophiles, energy transition, electrification, critical minerals, industrial biotechnologyHave a question or comment? Message us here:Text or Call (804) 505-5553Instagram / Twitter / LinkedIn / Youtube / Grow EverythingMusic by: Nihilore Production by: Amplafy Media
Protein engineering has traditionally been slow, expensive, and stuck in trial-and-error mode—but AI is changing everything. In this episode, we sit down with Elise De Reus, co-founder of Cradle Bio, to explore how generative AI is revolutionizing the way scientists design proteins for medicines, enzymes, and sustainable materials. Elise shares her journey from studying fungi and building high-throughput strain engineering systems at companies like Zymergen and Perfect Day, to creating an AI-powered platform that helps R&D teams generate better protein variants in less time and at lower cost. We discuss the massive design space of proteins, the role of machine learning in navigating that complexity, how Cradle balances computational predictions with biological reality, and what it will take for the bioeconomy to reach its trillion-dollar potential. Whether you're in pharma, industrial biotech, or just curious about the future of biology as a design problem, this conversation offers a fascinating look at how AI is becoming an essential tool for engineering the building blocks of life.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?Learn more at www.messaginglab.com/groweverythingChapters:(00:00:00) - The AI Revolution Meets Biology(00:01:00) - Why Erum Switched from ChatGPT to Claude (And What It Means for AI)(00:03:00) - Lab-Grown Meat Just Got Real: The Breakthrough That Changes Everything(00:06:00) - The Roadmap to a Trillion-Dollar Bioeconomy: Inside the AB4S Report(00:08:00) - Proteins 101: The Molecular Machines Running Your Life(00:10:00) - From Studying Fungi to Building AI Tools: Elise De Reus's Origin Story(00:12:00) - Inside Cradle Bio: The AI Studio Transforming How Scientists Design Proteins(00:15:00) - The "Short, Fat Data" Problem: Why Protein Engineering Needs Different AI(00:18:00) - Finding Needles in Infinite Haystacks: How Generative AI Navigates Protein Space(00:23:00) - When AI Is Confident But Wrong: Balancing Predictions with Biological Reality(00:27:00) - Speed vs. Caution: Why Pharma and Industrial Biotech Innovate Differently(00:30:00) - The $500 Billion Question: What's Really Blocking the Bioeconomy?(00:35:00) - Success Stories: How AI Unstuck Projects That Were Going Nowhere(00:38:00) - Sequence vs. Structure: Which AI Models Win at Protein Design?(00:41:00) - The Future Is Here: Better Data, Faster DNA Assembly, and Smarter Tools(00:43:00) - Quick Fire: Elise's Hot Takes on Biotech's Biggest Questions(00:47:00) - Biology as a Design Problem: Why This Changes EverythingLinks and Resources:CradleTurning lab-grown yeast into edible scaffoldingSynBioBeta Pass - Discount code: Grow Everything 166. The Great Reformulation: Joshua Lachter Rethinks How We Make Everything at ScaleTopics Covered:protein design, protein engineering, biotech, lab automation, biomanufacturing. synthetic biology, AI drug discovery, directed evolution, biologics, computational biology, enzyme optimizationHave a question or comment? Message us here:Text or Call (804) 505-5553Instagram / Twitter / LinkedIn / Youtube / Grow EverythingMusic by: Nihilore Production by: Amplafy Media
Kevin Webb, Managing Director of Superorganism, joins Erum and Karl to discuss why biodiversity is the next frontier for venture capital. After 15 years backing SaaS unicorns and marketplaces, Kevin made a radical pivot to launch a $25M fund focused exclusively on biodiversity-driven startups. In this conversation, Kevin breaks down why nature has been catastrophically undervalued in our economic systems, how his fund identifies venture-scale opportunities in everything from invasive species leather to AI-powered ecosystem monitoring, and why measuring biodiversity is infinitely harder than tracking carbon emissions. He shares portfolio highlights including companies turning Burmese pythons into luxury goods, explains why sea otters would make ideal board members, and reveals the cultural, technological, and regulatory shifts that could transform biodiversity from a conservation concern into a mainstream asset class within the next decade. This episode is essential listening for founders, investors, and anyone interested in the intersection of nature, technology, and capital.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?Learn more at www.messaginglab.com/groweverythingChapters:(00:00:00) - Nature as Undervalued Infrastructure(00:01:00) - AI, Intelligence Premium, and Economic Disruption(00:05:00) - Animation, Uploaded Intelligence, and Biotech Narratives(00:09:00) - Color, Bio-Dyes, and Experiencing the World(00:12:00) - Kevin Webb's Journey from SaaS to Biodiversity VC(00:17:00) - Why Biodiversity Is Harder to Quantify Than Carbon(00:21:00) - Superorganism's Investment Thesis and Portfolio(00:26:00) - Invasive Species as Business Opportunity: Python Leather(00:32:00) - Biodiversity, Human Health, and Disease Spillover(00:36:00) - Misconceptions About Building in Biodiversity(00:40:00) - Fund Raising, LPs, and Long-Term Capital(00:45:00) - Quick Fire Round: Sea Otters, Octopi, and Redwoods(00:50:00) - eDNA, Measurement, and the Future of Nature TechLinks and Resources:Superorganism131. Leaf It to Science: How Foray Bioscience's Ashley Beckwith is Reforesting the Future64. Swaying Away from Plastics: Julia Marsh's Seaweed Solutions159. The Future Is Fungi Awards: From Mushroom Dreams to Real-World ThingsThe Color FactoryThe 2028 Global Intelligence Crisis - Citrini Research Atoms vs.Bits - Citrini ResearchTopics Covered:biodiversity investing, biodiversity venture capital, Superorganism VC, Kevin Webb Superorganism, nature based solutions startups, invasive species business model, climate and biodiversity tech, impact investing in nature, biodiversity as an asset classHave a question or comment? Message us here:Text or Call (804) 505-5553Instagram / Twitter / LinkedIn / Youtube / Grow EverythingMusic by: Nihilore Production by: Amplafy Media
Sophia Xu, cofounder of Carbon Bridge, joins us to discuss how her company is revolutionizing gas fermentation with notebook-sized modular bioreactors that convert waste gases into valuable fuels and chemicals. From rejecting medical school to focus on climate biotech, to developing reactors 80% more energy efficient than traditional methods, Sophia shares how Carbon Bridge's platform enables wild-type methanotrophs to perform 500% better than genetically modified microbes. The conversation explores distributed manufacturing, the company's vision for an "app store" of microbial pathways, partnerships with Norwegian Cruise Lines, and why Sophia believes biology—not electrification—is key to decarbonizing heavy industry. We discuss deployment scenarios from dairy farms to breweries, the misconceptions about gas fermentation, and how Carbon Bridge is creating a new business model by selling bioreactors rather than end products.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?Learn more at www.messaginglab.com/groweverythingChapters:(00:00:00) - Sophia's Journey from Cancer Research to Climate Biotech(00:03:18) - AI in Biomanufacturing(00:06:00) - From Nanotechnology to Waste Gas Conversion(00:09:00) - Sophia's Path: Why Climate Over Medical School(00:11:00) - Biology as an Industrial Platform(00:11:48) - Visualizing Carbon Bridge: MacBook-Sized Bioreactors(00:14:00) - Navigating Unpredictability in Biological Systems(00:16:43) - Methanotrophs: The Wild-Type Microbes Behind the Tech(00:17:00) - Scaling by Stacking: From Lab to 80X Scale(00:18:00) - Sustainability Meets Economics: No Green Premium Required(00:21:00) - Performance Numbers: 80% More Efficient, 500% Better Than GMOs(00:23:00) - Distributed Manufacturing and the Server Farm Analogy(00:25:00) - Deployment Scenarios: Dairy Farms, Breweries, and Beyond(00:27:00) - Funding Insights: What ARPA-E, IndieBio, and SOSV Taught Them(00:28:53) - Business Model: Selling Bioreactors, Not End Products(00:30:00) - The App Store Vision for Microbial Pathways(00:32:00) - Carbon Conversion Over Carbon Removal(00:34:00) - Visioneering the Future: Reproducibility and the Biotech Revolution(00:36:00) - Quick Fire: Climate Myths, Hydrogen Skepticism, and More(00:39:00) - Post-Interview Reflections and Business Model SpinLinks and Resources:Links for Sophia's XuTopics Covered:CarbonBridge, climate biotech, gas fermentation, methane to methanol, modular bioreactor, distributed biomanufacturing, waste gas conversion, renewable methanol, industrial biotechnology, biomanufacturing infrastructureHave a question or comment? Message us here:Text or Call (804) 505-5553Instagram / Twitter / LinkedIn / Youtube / Grow EverythingMusic by: Nihilore Production by: Amplafy Media
John Cumbers returns to the Grow Everything podcast for his fourth appearance to discuss the cutting edge of synthetic biology and the upcoming SynBioBeta 2026 conference. From a man who's been bitten by snakes over 200 times to create universal anti-venom, to the race between the US and China in bio-manufacturing, John reveals why the bioeconomy is reaching an inflection point. We explore how AI is transforming organism design, the $50 million deals being struck for AI models in pharma, and why Chinese bio-manufacturing firms are achieving profitability while Western companies struggle. John also shares his vision for cellular reprogramming and longevity, discusses the controversial rollback of US environmental policy, and explains why the "ChatGPT moment" for biology is closer than we think. Plus, learn about stem cell tissue banks that could revolutionize replacement therapy and why SynBioBeta 2030 will actually happen on the moon.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?Learn more at www.messaginglab.com/groweverythingChapters:(00:00:00) - Welcome Back: John Cumbers' Fourth Appearance on Grow Everything(00:01:00) - Death Becomes Her: Longevity on Broadway(00:03:00) - Listening Bars and Ambient Music Experience(00:04:00) - The Peptide Revolution: From Gray Market to Mainstream(00:07:00) - Trump Administration Revokes Clean Air Act: Impact on Biotech(00:12:00) - Biomanufacturing as Economic Development and Climate Solution(00:13:00) - AI, Space, and Solar Energy: Elon Musk at World Economic Forum(00:16:00) - Data Centers in Space: The Future of Energy(00:18:00) - Introducing John Cumbers and SynBioBeta 2026(00:19:00) - The Man Bitten by 200+ Snakes: Universal Anti-Venom Story(00:22:00) - The Schmidt Pain Index and Extreme Science(00:23:00) - History and Evolution of SynBioBeta Over 14 Years(00:25:00) - Bio 500: Big Companies Transforming with Biotech(00:27:00) - Plant-Based Sales Slowdown and Consumer Bio Trends(00:30:00) - Discovery vs. Commercialization: Why 80% of Startups Fail on Execution(00:34:00) - Default Alive Companies: Bootstrapping the Bioeconomy00:36:00) - AI Meets Biology: When's the ChatGPT Moment?(00:39:00) - Sidewinder DNA Assembly: Revolutionary Build Technology(00:42:00) - Design-Build-Test-Learn: Closing the Loop with Self-Driving Labs(00:43:00) - China's Biomanufacturing Dominance: What the West Can Learn(00:49:00) - Free Market Capitalism vs. Centralized Planning(00:52:00) - Should SynBioBeta Take Political Stands?(00:55:00) - Longevity Revolution: Cellular Programming and Stem Cell Banks(00:59:00) - Death Becomes Her and the Market for Living Forever(01:01:00) - AI and Bio: The Singularity is Here(01:03:00) - Human Genome Engineering and the Meta Simulation(01:05:00) - Quick Fire Round: Lantern Bioworks, Moon Conference, and Awards(01:07:00) - Closing: SynBioBeta Discount Code and Final ThoughtsLinks and Resources:Synbiobeta website. Join us! Use code: "Grow Everything" for a discountOneSkinReplacement theory of aging - Jean HebertTopics Covered:synbio, synthetic biology, bioengineering, conferences, networks, biotech, biology, bioliteracy, Bio500, AI and BioHave a question or comment? Message us here:Text or Call (804) 505-5553Instagram / Twitter / LinkedIn / Youtube / Grow EverythingMusic by: Nihilore Production by: Amplafy Media
Karl and Erum break down how biology is transforming the production of everything from cosmetics to construction materials. They explore why the petrochemical era is giving way to biological manufacturing, examining both the spectacular failures of early biofuels and the emerging success stories of companies like K18 and Mango Materials. Karl and Erum explain the fundamentals of fermentation, precision fermentation, and cell-free manufacturing, while introducing concepts like distributed biomanufacturing and "dirty biology." Drawing on insights from previous guests including Doug Friedman, Michelle Stansfield, Veronica Breckenridge, and Phil Morle, they reveal why 95% of executives are now pursuing bio-solutions and how three converging forces—falling technology costs, rising consumer expectations, and new infrastructure—are making this the moment for biomanufacturing to finally deliver on its promise.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?Learn more at www.messaginglab.com/groweverything Chapters:(00:00:00) - Why AI might just become our CEO (plus haircuts, Pilates, and gene therapy for hearing loss)(00:02:05) - Eli Lilly's $1B gene therapy deal for hearing loss(00:05:00) - Long Now podcast recommendation and NASA astrobiologist Lynn Rothschild(00:07:00) - Discussion of Apple TV's Scion and Drops of God(00:11:00) - What is biomanufacturing and why does it matter?(00:13:00) - The history of petrochemicals as "green technology"(00:16:00) - The opportunity: removing gigatons of carbon and unlocking trillion-dollar markets(00:19:00) - Types of biomanufacturing: fermentation, precision fermentation, and continuous fermentation(00:22:00) - Cell-free manufacturing and plant cell bioreactors(00:26:00) - Growing products with mycelium and dirty biology approaches(00:29:00) - Why biomanufacturing has been hard: the valley of death(00:30:00) - The biofuels bust and lessons from 60 failed companies(00:34:00) - Infrastructure challenges and the capacity gap(00:36:00) - New solutions: performance over sustainability and the K18 example(00:40:00) - Orchestration beats invention: connecting the entire value chain(00:43:00) - Distributed biomanufacturing and making products from waste(00:48:00) - The bio-better reality: what consumers and CPG companies need(00:51:00) - Three forces converging to make biomanufacturing work now(00:53:00) - Quickfire questions: luxury vs. commodities, funding, and AI's roleLinks and Resources:Links and Resources DOCTopics Covered: biomanufacturing 101, industrial biotechnology, precision fermentation, continuous fermentation, cell-free biomanufacturing, distributed biomanufacturing, dirty biology, bio-based materials, performance vs sustainability, CPG reformulationHave a question or comment? Message us here:Text or Call (804) 505-5553Instagram / Twitter / LinkedIn / Youtube / Grow EverythingMusic by: Nihilore Production by: Amplafy Media
Daniel Scharff, founder of Startup CPG, joins the Grow Everything podcast to share how he built the world's largest community for emerging consumer brands. With 35,000 members in their Slack channel and over 75 in-person events annually, Startup CPG is democratizing access to retail buyers, investors, and industry resources that would typically cost founders thousands in consulting fees. Daniel discusses the harsh realities of CPG entrepreneurship—including why only 20-25% of brands survive beyond a few years—and shares his playbook for success: prioritize great branding and taste over health claims, build scrappy and resourceful, and delay fundraising until you can command a meaningful valuation. He reveals patterns he's observed across thousands of brands, from the danger of copycat products in oversaturated categories (looking at you, chili crisps and prebiotic sodas) to the power of in-person connections for discovering innovation. Daniel also explains why Startup CPG operates on a "do good, do well" model, offering free resources to brands while building a sustainable business through sponsorships and events—and why he believes this approach could transform other industries beyond CPG.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?Learn more at www.messaginglab.com/groweverything Chapters:(00:00:00) - Fancy Weekends, Le Bernardin, and the Met(00:03:00) - Drops of God Season 2 and Art at the Met(00:06:00) - Automatic Noodle Book Discussion(00:09:00) - Claude Bot and AI Tools for Content Creation(00:13:00) - Introducing Daniel Scharff and Startup CPG(00:16:00) - Daniel's Journey from Mars to Just Egg to Startup CPG(00:21:00) - Building the World's Largest CPG Community(00:27:00) - Patterns of Success and Failure in CPG Brands(00:33:00) - What Makes Products Stand Out: Innovation vs. Copycats(00:38:00) - The Role of Biology and Health Claims in CPG(00:42:00) - Why In-Person Events Still Matter in a Digital World(00:50:00) - The Startup CPG Podcast and Media Platform(00:54:00) - Fundraising Strategies: When to Raise and How Much(01:00:00) - Quick Fire Questions with Daniel(01:03:00) - Final Thoughts and Wrap-UpLinks and Resources:Startup CPGStartup CPG Formulator DirectoryStartup CPG ResourcesNoguchi’s Waterstone at the METAutomatic Noodle by Annalee Newitz166. The Great Reformulation: Joshua Lachter Rethinks How We Make Everything at Scale165. Biology Behind the Brands: Inside P&G’s Two-Century Story164. From Plasmids to Pallets: How Erin Marasco Scales Biology at CargillTopics Covered: CPG, consumer packaged goods, startups, community, Startup CPG, innovationHave a question or comment? Message us here:Text or Call (804) 505-5553Instagram / Twitter / LinkedIn / Youtube / Grow EverythingMusic by: Nihilore Production by: Amplafy Media
Joshua Lachter, co-founder of Synonym, joins us for an in-depth conversation about the future of biomanufacturing and what he calls "the great reformulation." We explore how biology is poised to replace petrochemicals across industries, the infrastructure challenges holding back commercial scale production, and why standardization is critical for mass adoption. Joshua shares insights from Synonym's work building commercial biomanufacturing facilities, including their groundbreaking project in Decatur, Illinois. From GLP-1s to microplastics, we discuss how bio-based products can deliver superior performance while addressing health and environmental concerns. This episode is essential listening for anyone interested in the commercialization of industrial biotech, the economics of biomanufacturing, and the path toward a reformulated supply chain built on biology.(00:00:00) - Snowstorm updates from NYC(00:03:00) - Tech Meets Pharma: The Data Revolution(00:09:00) - Mr. Beast, Upside Foods, and Colossal Biosciences(00:14:00) - Joshua's Background and Why He Founded Synonym(00:18:00) - Financialization and Standardization of Biomanufacturing(00:25:00) - Early Assumptions That Turned Out Wrong(00:38:00) - The Great Reformulation: Biology vs. Petrochemicals(00:48:00) - GLP-1s and Nature-Inspired Innovation(00:54:00) - Better with Bio: Synonym's Partnership with Brentag(00:59:00) - Quickfire Questions(01:03:00) - Wrap-Up & Final ThoughtsEpisode Links:SynonymBetterWith.BioThe Great Reformulation Primient and Synonym Forge Strategic Partnership to Propel U.S. Bioproduct InnovationNYC Mayor Zohran Mamdani Snowstorm Prep VideoMr. Beast video: $1 vs $1,000,000,000 Futuristic Tech!Edward Shenderovich epAmy Trejo and JC Garcia Garcia epSuveen K18 ep Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?Learn more at www.messaginglab.com/groweverythingTopics Covered: biotech, industry, biomanufacturing, bioprocessing, industrial biotech, Great Reformulation, consumer packaged goods, CPG, biotech R&D, chemical engineering, bioengineering, AI in biomanufacturingHave a question or comment? Message us here:Text or Call (804) 505-5553Instagram / Twitter / LinkedIn / Youtube / Grow Everything
Karl and Erum sit down with Amy Trejo and Jose Carlos Garcia Garcia from Procter & Gamble to uncover how one of the world's largest consumer goods companies is leveraging biotechnology to innovate at unprecedented scale. Founded 189 years ago as a bio-waste upcycling partnership between a candle maker and a soap maker, P&G has always been rooted in biomaterials innovation—from pioneering laundry enzymes in the 1960s to developing cold water enzyme technologies that have saved billions in energy costs. Amy and JC reveal what makes biotech innovations stick in the marketplace (hint: it's all about performance), share candid advice for startups hoping to partner with P&G, and explain why the company views biotech as a critical enabler of both sustainability and superior consumer experiences. They discuss common misconceptions about working with large CPG companies, the importance of reducing ideas to practice, and how P&G's connect-and-develop model creates win-win partnerships that can impact billions of consumers worldwide. Whether you're a biotech founder, investor, or enthusiast curious about how innovative materials make it from lab to everyday products, this conversation offers rare insights into the intersection of consumer goods, biotechnology, and global scale manufacturing.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?Learn more at www.messaginglab.com/groweverything Chapters:(00:00:00) - Introduction and Opening Remarks(00:01:00) - Erum's Article on Industrial Biomanufacturing for Lichen Ventures(00:04:00) - The Vision of Boom Towns and Interplanetary Innovation(00:07:00) - Introduction to Amy Trejo and JC Garcia Garcia from P&G(00:11:00) - Amy and JC's Backgrounds and Roles at P&G(00:13:00) - Biotech Innovations Throughout P&G's 189-Year History(00:19:00) - What Makes Biotech Innovations Stick: Performance Over Everything(00:22:00) - Biggest Misconceptions About Partnering with Large CPG Companies(00:29:00) - How to Approach P&G: Show Product, Generate Data, Demonstrate Performance(00:31:00) - The Power of Reapplication Across Product Categories(00:35:00) - Successful Biotech Partnerships: SK-II, Align, New Chapter, Base Camp Research(00:39:00) - What Catches P&G's Attention at Conferences and Trade Shows(00:42:00) - The Role of Storytelling in Biotech Innovation and Consumer Engagement(00:47:00) - Five-Year Vision: The Future of CPG and Biotech Partnerships(00:49:00) - One Piece of Advice for Biotech Innovators: Reduce Ideas to Practice(00:52:00) - Quickfire Questions with Amy and JC(00:53:00) - Closing Thoughts: Impacting Billions of Lives Through Partnership(00:54:00) - Karl and Erum's Recap and Key TakeawaysLinks and Resources:Procter & Gamble (P&G)P&G Connect + DevelopP&G PartnershipsStellar: A World Beyond Limits and How To Get ThereIndustrial Biomanufacturing Needs Its Manhattan Project Moment by Erum Azeez Khan107. Glow Big or Go Home: Andy Bass's Journey with Glowing Oceans17. Beauty and the Biome with Jasmina Aganovic of ArcaeaTopics Covered: biotech, industry, biomanufacturing, bioprocessing, agriculture, agritech, strain engineering, biotech R&D, feedstocks, chemical engineering, bioengineeringHave a question or comment? Message us here:Text or Call (804) 505-5553 Music by: Nihilore Production by: Amplafy Media
We kick off our CPG series with Dr. Erin Marasco, Senior Director of Global Biology at Cargill, who leads innovation in ingredient discovery, strain development, and biotech applications. Erin takes us on a fascinating journey from the fundamentals of fermentation to the complexities of scaling biotech products from lab bench to global supply chains. We explore Cargill's 30-year history in biomanufacturing, discuss why terms like "precision fermentation" might be doing more harm than good, and learn what it really takes for startups to partner with multinational companies. Erin shares insights on feedstock diversity across continents, the future of nutritional bioactives in everyday foods, and why success in biotech means moving from "novel" to "preferred." This conversation is essential listening for anyone interested in how biology is quietly transforming every aisle of the grocery store.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?Learn more at www.messaginglab.com/groweverything Chapters:(00:00:00) - Introduction & New Year Kickoff — Welcome to 2026 and the start of our CPG series!(00:01:00) - JP Morgan Conference & South Africa Travel(00:05:00) - New Food Pyramid Controversy(00:10:00) - Introducing Erin Marasco & Cargill's Role in Biotech(00:17:00) - Where Biotech Creates Real Leverage at Cargill(00:21:00) - Demystifying Fermentation: Why Now?(00:26:00) - How Cargill Partners with Startups(00:30:00) - Biggest Misconceptions About Working with Big Companies(00:33:00) - What Product Readiness Means to Cargill(00:38:00) - Plasmids to Pallets: Successful Partnership Examples(00:47:00) - Feedstock Diversity Across Continents(00:53:00) - The Future: Nutrition as Everyday Food(00:58:00) - Quick Fire Questions & Retiring "Precision Fermentation"(01:03:00) - Wrap-Up & What's Next in the CPG SeriesLinks and Resources:CargillCargill Fermentation BlogFermentation: nature's original biotech by CargillCantabria Labs (sunscreen from plant extracts)Viro - Sugarcane StrawsSawubona Mycelium Heliocare Cantabria Labs Andreesen Horowitz, VC fund, raised a $15 billion Topics Covered: biotech, industry, biomanufacturing, bioprocessing, agriculture, agritech, strain engineering, biotech R&D, feedstocks, chemical engineering, bioengineeringHave a question or comment? Message us here:Text or Call (804) 505-5553 Music by: Nihilore Production by: Amplafy Media
Karl and Erum kick off 2026 by reviewing their 2025 forecasts—celebrating the wins (DeSci's rise, waste as a resource, AI-biology convergence) and acknowledging the misses (no biotech M&A boom, no quantum biology breakthrough yet). Then they unveil their boldest predictions for the year ahead: the first functional AI-composed genome entering production, a major non-sterile biomanufacturing facility breaking ground, biological arbitrage creating competitive advantages against tariffs, consumer-held health records surpassing traditional medical data in clinical significance, space-manufactured drug crystals entering human trials, definitive proof of alien life, and AI-enabled communication with whales and other animals. They also welcome Lizette Couto, who joins the podcast to provide science definitions and explanations throughout episodes going forward. From dirty biology manifestos to peptide proliferation to interspecies communication, this episode maps the frontiers where synthetic biology, AI, space technology, and consumer adoption collide. Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?Learn more at www.messaginglab.com/groweverything Chapters:(00:00:00) - 🎙️ Welcome to 2026: The Year Biology Gets Real(00:01:00) - Introducing Lizette Couto: Science Definitions and Podcast Updates(00:03:00) - 2025 Predictions Review: Using AI to Analyze Episodes(00:04:00) - What We Got Wrong: H5N1, Quantum Biology, and M&A Activity(00:10:00) - What We Got Right: DeSci's Rise and the BIO Token(00:12:00) - Waste as a High Value Resource: Agricultural to Urban Applications(00:14:00) - Onshoring and Government Funding: A Crushing Year for Science(00:18:00) - AI and Biology Convergence: From Reading to Composing Genomes(00:20:00) - Microbiome and Longevity in Mainstream Culture(00:23:00) - 2026 Prediction #1: The First AI-Composed Genome Goes Into Production(00:26:00) - 2026 Prediction #2: Major Non-Sterile "Dirty Biology" Manufacturing Facility(00:30:00) - 2026 Prediction #3: Biological Arbitrage Creates 15-20% Margin Advantage(00:34:00) - 2026 Prediction #4: Consumer Health Records Become More Significant Than Medical Records(00:36:00) - 2026 Prediction #5: Consumer Biotech Gains on Industrial Biotech (The Bathroom Shelf Wins)(00:41:00) - 2026 Prediction #6: Space-Manufactured Drug Crystals Enter Human Clinical Trials(00:44:00) - 2026 Prediction #7: We'll See Proof of Alien Life(00:48:00) - 2026 Prediction #8: AI Enables Clear Communication with Whales and Other Animals(00:51:00) - Closing Thoughts and Upcoming CPG Series PreviewLinks and Resources:H5N1 bird fluNovo Nordisk Quantum Computing Program145. Decentralized Science 101: Defining DeSci with the Experts146. Pump It Up: Benji Leibowitz on DAO-ing Science Differentlybio.xyzHairDAOMango Materials123. From Gas to Glam: Molly Morse Discusses Mango Materials' Biodegradable InnovationsIndustrial Microbes113. Microbe Mission Possible: Noah Helman Discusses iMicrobes' Quest to Turn Waste into WealthSymmetry Wood154. No Trees Were Harmed: Symmetry Wood's Gabe Tavas on Growing Wood from WasteNIH and NSF alarming funding cutsOneSkinEVO 2122. Ecohacking the Planet: Daniel Goodwin of Homeworld Collective Brews Up Planetary-Scale SolutionsThe Future of Science: Modernizing the U.S. Scientific Enterprise152. Crystals in the Cosmos: Varda Rewrites Drug Formulation in MicrogravityTopics Covered: biotech, industry, predictions, biomanufacturing, consumer biotechHave a question or comment? Message us here:Text or Call (804) 505-5553 Music by: Nihilore Production by: Amplafy Media
Karl and Erum kick off 2026 with deep reflections on prosperity, consciousness, and the idea that we might be living in a simulation. But the real focus is on a concept that could make or break biotech companies: orchestration. They dive into why most biotech innovations outside of pharma struggle to commercialize and introduce the idea of value chain syndication—bringing together innovators, manufacturers, investors, and big incumbents to create entire ecosystems rather than just individual deals. Using examples like K18 Hair's marketing orchestration and the urgent need to replace Red Dye 40, they break down how founders can architect strategic "seed deals" that build toward transformative industry shifts. This isn't about traditional sales or business development—it's about becoming the center of an ecosystem that includes everyone from ingredient suppliers to end customers. With tailwinds from geopolitical changes, supply chain concerns, and increasing demand for bio-based solutions, the time for orchestration is now. Whether you're a founder trying to scale or a big company looking to innovate, this episode shows you how to think bigger than your own company and build the infrastructure for a bio-based future.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?Learn more at www.messaginglab.com/groweverything Chapters:(00:00:00) - Welcome and New Year reflections from California and Cape Town(00:01:00) - Prosperity, money circulation, and building a better society(00:04:23) - Consciousness, simulation theory, and the philosophy of everything(00:09:00) - Why we're replaying the orchestration episode(00:10:00) - What is orchestration and why it's not just sales or business development(00:15:00) - Why biotech companies struggle to commercialize outside pharma(00:18:00) - Value chain syndication and manufacturing orchestration explained(00:20:00) - Seed deals: How to start small and build toward the big picture(00:22:00) - The Red Dye 40 case study: Architecting an ecosystem for change(00:27:00) - Why founders need to think differently and become deal architects(00:31:00) - Why now? Geopolitical and economic tailwinds for biomanufacturing(00:34:00) - Risks, rewards, and the 5-10 year arc of ecosystem building(00:37:00) - Final reflections and how to get started with orchestrationLinks and Resources:MessaginglabNational Security Commission on Emerging Biotechnology's Report: Charting the Future of BiotechnologyRed Dye ban153. Ghosts of Biotech Past: Veronica Breckenridge’s Playbook for Smarter Scaling149. Beyond Capital: Phil Morle of Main Sequence Ventures on Collaboration as the New Competitive Edge120. Busting Biotech's Bottlenecks: Veronica Breckenridge on the Path to Industrial Scale26. Breaking Bad Hair Habits with Biology: Suveen Sahib's K18 Rescues Your StrandsStar Talk Neil deGrasse TysonTopics Covered: biotech, CPG, business models, industry, bacterial cellulose, fermentationHave a question or comment? Message us here:Text or Call (804) 505-5553 Instagram / Twitter / LinkedIn / Youtube / Grow EverythingEmail: groweverything@messaginglab.comMusic by: NihiloreProduction by: Amplafy Media
In this special holiday replay episode, we revisit our conversation with Ashley Beckwith, founder of Foray Biosciences, who shares her groundbreaking work in plant cell culture and tissue engineering. Growing up in Colorado, Ashley watched forests disappear to housing development and wildfire—experiences that sparked her lifelong mission to reimagine how we produce plant materials. After training as an engineer and working in medical device development, she pivoted to apply tissue engineering concepts to plants, initially exploring lab-grown wood before discovering a more fundamental problem: the lack of accessible, efficient plant cell culture processes. Today, Foray develops fabricated seeds for forest restoration, creates harvest-free plant products, and builds AI-powered tools to accelerate plant science R&D. Ashley explains why plant cells are the fundamental building blocks for everything from molecules to materials to entire ecosystems, and how her company is working to solve the seed shortage crisis that prevents us from restoring 94% of post-wildfire sites. She also discusses the potential for de-extinction of recently lost plant species in California and the importance of creating regenerative rather than extractive relationships with plant systems. This conversation explores the intersection of synthetic biology, forestry, and biomanufacturing while reminding us that we are all, whether we know it or not, plant people.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?Learn more at www.messaginglab.com/groweverything Chapters:(00:00:00) - Holiday Greetings and Stranger Things on Broadway(00:04:41) - Introducing Ashley Beckwith and Foray Biosciences(00:07:17) - Growing Up in Colorado: Watching Forests Disappear(00:10:48) - From Medical Engineering to Plant Biology(00:15:00) - The Lab-Grown Wood Experiment(00:18:58) - Understanding Plant Cells as Versatile Production Agents(00:25:00) - Fabricated Seeds for California Biodiversity Restoration(00:33:00) - Addressing the Wildfire Restoration Seed Shortage(00:42:00) - Building the Plant Operating System with AI(00:50:00) - Why We're All Plant PeopleLinks and Resources:Foray BiosciencesSF500 (Argentinian Global Venture Fund)Syensqo Corporate Venture FundH.C. WainwrightUniversity of Vermont - Dr. Steve KellerUniversity of Maryland - Dr. Matt FitzpatrickForay Biosciences154. No Trees Were Harmed: Symmetry Wood's Gabe Tavas on Growing Wood from WasteTopics Covered: developmental biology, morphology, morphospace, planarians, electroceuticals, bioelectricity, tissue regeneration, biomedical applications, holidays, ChristmasHave a question or comment? Message us here:Text or Call (804) 505-5553 Instagram / Twitter / LinkedIn / Youtube / Grow EverythingEmail: groweverything@messaginglab.comMusic by: NihiloreProduction by: Amplafy Media
In this episode, Karl and Erum speak with Aradhita Parasrampuria, founder of CellSense, about revolutionizing the fashion embellishment industry through biology. Aradhita shares her journey from witnessing toxic dye masters in Gujarat textile factories to creating biodegradable sequins, beads, and buttons using algae and bacterial cellulose. She explains how her materials can be produced at room temperature, glow in the dark through bioluminescence, and are manufactured through an automated system that eliminates exploitative manual labor. With one in five garments containing embellishments, CellSense addresses a massive market while tackling microplastic pollution, worker health issues, and the 2027 EU ban on microbeads and lead. Aradhita discusses successful pilots with fashion brands and skincare companies, the challenges of achieving vivid colors and iridescence with biomaterials, and her vision for a circular system where anyone can upload a design and receive custom bioplastic solutions. The conversation explores the intersection of design, biotechnology, and sustainability, demonstrating how biology can create materials that don't just replace plastics—they surpass them.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?Learn more at www.messaginglab.com/groweverything Chapters:(00:00:00) - Introduction: Fungi as environmental game-changers(00:26:18) - Podcast updates and Michael Levin episode highlights(02:10:35) - Ashley Beckwith and Foray Biosciences: mining fungal biodiversity(04:57:22) - The untapped power of mycelium in biotechnology(08:04:15) - Launching the Future is Fungi Award(08:58:40) - Susanne Gløersen: Why fungi deserve to be core technology(00:12:09) - Fungi's role in solving climate, pollution, and soil degradation(00:27:06) - Quickfire questions with Susanne Gløersen(00:29:14) - Ricky Casini of Michroma: replacing synthetic food dyes with fungi(00:38:10) - Scaling fermentation capacity in South Korea(00:38:45) - Pitching fungal colorants to food manufacturers(00:40:22) - Regulatory wins and transparency in natural colors(00:41:19) - The future of fungal bio-factories in food production(00:43:05) - Scaling up production and strategic partnerships(00:44:09) - Why color matters in consumer packaged goods(00:45:46) - Winning the Future is Fungi Startup Award(00:46:59) - Quickfire questions with Ricky Cassini(00:49:02) - Dr. Britta Winterberg introduces Mycolever's clean beauty mission(00:50:00) - Fungal bio-compounds replacing petrochemicals in cosmetics(00:52:10) - Technical challenges and breakthroughs in fungal biotech(00:59:52) - Quickfire questions with Dr. Britta Winterberg(01:02:54) - Final reflections on the fungal innovation revolutionLinks and Resources:CellsenseCellsense Partnership with the United NationsBioculture Event hosted by Biofabricate x Juniper VCArahita - LinkedinMountain and The Sea - Ray Nayler 138. Living Textures, Wild Pigments: Suzanne Lee on Nature’s New Aesthetic Toolbox154. No Trees Were Harmed: Symmetry Wood's Gabe Tavas on Growing Wood from WasteGrow Everything SubstackGrow Everything PatreonTopics Covered: biomaterials, fashion, embellishments, sequins, bacterial cellulose, fermentationHave a question or comment? Message us here:Text or Call (804) 505-5553
Karl and Erum explore the untapped potential of fungi through three groundbreaking interviews. First, they speak with Susanne Gloersen, founder of the Future is Fungi Award, about why fungi represent the next frontier in biotech and how her global platform is accelerating fungal innovation across industries—from soil remediation to firefighting foam. Next, they sit down with Ricky Cassini of Michroma, winner of the Future is Fungi Award, who explains how his team engineers fungi to produce natural food colorants that outperform synthetic dyes and plant-based alternatives, offering 50x more potency than traditional options while being heat and pH stable. Finally, they interview Dr. Britta Winterberg of Mycolever, runner-up of the award, who discusses how her company uses fungal biodiversity to create sustainable bio-compounds for cosmetics, including emulsifiers and enhanced beauty oils that replace petrochemicals without compromising performance. Throughout the episode, the hosts highlight recent developments like MIT researchers using fungal compounds to treat brain cancer, FDA's phase-out of synthetic dyes, and the growing shift toward bio-based ingredients in food, cosmetics, and beyond.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?Learn more at www.messaginglab.com/groweverything Chapters:(00:00:00) - Introduction: Fungi as environmental game-changers(00:26:18) - Podcast updates and Michael Levin episode highlights(02:10:35) - Ashley Beckwith and Foray Biosciences: mining fungal biodiversity(04:57:22) - The untapped power of mycelium in biotechnology(08:04:15) - Launching the Future is Fungi Award(08:58:40) - Susanne Gløersen: Why fungi deserve to be core technology(00:12:09) - Fungi's role in solving climate, pollution, and soil degradation(00:27:06) - Quickfire questions with Susanne Gløersen(00:29:14) - Ricky Casini of Michroma: replacing synthetic food dyes with fungi(00:38:10) - Scaling fermentation capacity in South Korea(00:38:45) - Pitching fungal colorants to food manufacturers(00:40:22) - Regulatory wins and transparency in natural colors(00:41:19) - The future of fungal bio-factories in food production(00:43:05) - Scaling up production and strategic partnerships(00:44:09) - Why color matters in consumer packaged goods(00:45:46) - Winning the Future is Fungi Startup Award(00:46:59) - Quickfire questions with Ricky Cassini(00:49:02) - Dr. Britta Winterberg introduces Mycolever's clean beauty mission(00:50:00) - Fungal bio-compounds replacing petrochemicals in cosmetics(00:52:10) - Technical challenges and breakthroughs in fungal biotech(00:59:52) - Quickfire questions with Dr. Britta Winterberg(01:02:54) - Final reflections on the fungal innovation revolutionLinks and Resources:Future is Fungi AwardsFuture is Fungi Award WinnersThe Future is Fungi Award on LinkedInmichroma - 1st place winner Michroma partners with CJ CheilJedang to advance precision fermented colorsMycolever - 2nd place winnerXPRIZEThe language of fungi - Andrew AdamatzkyCosmetic 360 Event156. When Matter Makes Decisions: Michael Levin on the Intelligence of Form158. Mycelium On, Sound Off: How GOB's Lauryn Menard Makes Biomaterials Feel Like Culture126. Sizzling Success: Eben Bayer of MyForest Foods on Scaling Mycelium Magic46. Meat the Future: How Paul Shapiro is Brewing Superfoods at Better Meat Co.131. Leaf It to Science: How Foray Bioscience's Ashley Beckwith is Reforesting the FutureTopics Covered: mycelium, fungi, mushrooms, Future is Fungi, bioinnovation, biotech, mycoremediation, food dyes, personal care and beautyHave a question or comment? Message us here:Text or Call (804) 505-5553
Lauryn Menard, co-founder of Gob, joins us to discuss how she's tackling the 40 billion petroleum-based earplugs produced annually by creating the first biodegradable, mycelium-based alternative. Named one of Fast Company's Most Innovative Companies of 2025 and featured in Time Magazine's Best Inventions, Lauryn shares her journey from industrial designer to biotech entrepreneur. She explains why she chose mycelium over other biomaterials, how she scaled production without building a factory from scratch, and her strategy for bringing sustainable products to mainstream consumers through cultural relevance—partnering with artists like Billie Eilish and Chappell Roan at major music venues. Lauryn also reveals her vision for Gob's future: replacing an entire category of single-use products, from cotton pads to condoms, with materials that return to the earth. This conversation explores the intersection of design, biomaterials, entrepreneurship, and the urgent need for better infrastructure to support a regenerative economy.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?Learn more at www.messaginglab.com/groweverything Chapters:(00:00:00) - Introduction: Lauryn's favorite subject - nature's zero waste system(00:06:00) - Lauryn's journey from luxury design to founding Gob(00:09:00) - The 40 billion earplug problem and material innovation(00:11:00) - Beginning with the end in mind: designing for product end-of-life(00:13:00) - Why mycelium? Finding the perfect material match(00:17:00) - Scale and volume: why small products have massive impact(00:22:00) - From concept to cylinder: the design process and user testing(00:24:00) - Cultural relevance over sustainability marketing(00:30:00) - Teaching the next generation of bio-designers at CCA(00:42:00) - Gob's future: replacing entire categories of single-use productsLinks and Resources:GOBEcovative138. Living Textures, Wild Pigments: Suzanne Lee on Nature’s New Aesthetic Toolbox126. Sizzling Success: Eben Bayer of MyForest Foods on Scaling Mycelium MagicFacts Machine - Science, comedy & trivia showTopics Covered: biomaterials, single use goods, FCMG, mycelium, ear plugs, entrepreneurship, branding, storytelling, biofabricationHave a question or comment? Message us here:Text or Call (804) 505-5553 Instagram / Twitter / LinkedIn / Youtube / Grow EverythingEmail: groweverything@messaginglab.com
In this Thanksgiving replay, we revisit our conversation with Paul Shapiro, co-founder and CEO of Better Meat Co, who's pioneering the use of mycelium-based proteins as a sustainable alternative to animal meat. Paul shares his remarkable journey from starting an animal welfare organization in high school to becoming a biotech entrepreneur. He explains how fungi fermentation creates protein-rich, meat-like textures in less than 24 hours without the environmental toll of traditional agriculture. The episode explores the science behind mycoprotein, the challenges facing the alternative protein industry, the need for government investment in biomanufacturing, and why fungi may be the key to feeding both Earth and future space travelers. Paul also discusses Better Meat Co's recent $31 million Series A funding and their mission to make sustainable protein accessible at scale.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?Learn more at www.messaginglab.com/groweverything Chapters:(00:00:00) - Could Fungi Replace Factory Farms Forever?(00:01:00) - Welcome: TEDx MIT, Planetary Action & What's Growing(00:03:00) - Intelligence Beyond Brains: Reflecting on Michael Levin(00:06:00) - Thanksgiving Special: Gratitude for the Biotech Community(00:10:00) - Meet Paul Shapiro: From Activist to Mycoprotein Pioneer(00:13:00) - Origin Story: Fighting for Animals Led to Building Better Meat(00:19:00) - Alt Protein 2.0: What's Changed Since the 2018 Hype Cycle(00:24:00) - The Subsidy Problem: Why Meat Gets Billions & Clean Protein Gets Nothing(00:31:00) - Mycoprotein 101: Why Fungi Beat Plants for Meat Texture(00:38:00) - Engineering Neurospora: 24-Hour Fermentation at Scale(00:43:00) - Designing Super Strains: Breeding Microbes for Performance(00:48:00) - Creating Craveable Protein: Flavor Science & B2B Strategy(00:51:00) - Space Food Systems: Why Astronauts Will Farm Fungi, Not Cows(00:56:00) - Biomanufacturing Infrastructure: The $31M Series A Story(01:00:00) - Industry Reality Check: Cultivated Meat's Path Forward(01:03:00) - Beyond Food: Mycoremediation & Paul's Business for Good Podcast(01:05:00) - Closing Thoughts: Solving the Flavor Challenge & Scaling ImpactLinks and Resources:Better Meat Co.Time's Best Inventions of 2025Paul ShapiroClean Meat Novel by Paul ShapiroHomeworld Collective Cascade Bio33. Purple Reign, A Purple Tomato with a Genetic Twist, Nathan Pumplin of Norfolk Healthy Produce83. Bottoms Up: Microbe Mixology with Zbiotics' Zack Abbott156. When Matter Makes Decisions: Michael Levin on the Intelligence of FormJohn Werner - TEDxThe Mountain in the Sea by Ray NaylerTopics Covered: developmental biology, morphology, morphospace, planarians, electroceuticals, bioelectricity, tissue regeneration, biomedical applications, Have a question or comment? Message us here:Text or Call (804) 505-5553 Instagram / Twitter / LinkedIn / Youtube / Grow EverythingEmail: groweverything@messaginglab.com







