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Listen to veterinary professionals from the Beef Cattle Institute at Kansas State University talk about a variety of topics within cattle health, nutrition, reproduction, and science. New episodes of Bovine Science with BCI are posted each Monday.
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In this episode of Tox Talk on Bovine Science, Dr. Brad White and Dr. Scott Fritz discuss a case where multiple two-month-old calves in a dry lot died with minimal clinical signs. Initial differentials included infectious disease, nutritional issues, and ryegrass staggers, but necropsy and testing were largely unrewarding. Ultimately, elevated tissue lead levels confirmed lead poisoning, even though no clear source was identified. The case highlights the importance of considering lead toxicity in young calves with neurologic signs, especially when they have access to areas outside their normal environment.
In this episode of Herd Health on Bovine Science, the experts discuss a recent study on factors associated with bull breeding soundness exam (BSE) failure. The veterinarians explain that both intrinsic factors, such as age and prior failure, and extrinsic factors, such as season and environmental conditions, influence whether a bull passes or fails. They highlight that sperm morphology is one of the most important indicators of fertility, often more predictive than other measures. Overall, the episode emphasizes interpreting BSE results in context to make better management and culling decisions.
Article Discussed
In this episode of BCI After the Abstract, the veterinarians explore a pharmacokinetic study on the use of methylene blue in cattle to determine safe withdrawal periods after treatment. The experts walk through how researchers tracked drug levels in blood, milk, and tissues to estimate when residues fall below safe thresholds. They emphasize that previous guidance lacked data, forcing veterinarians to rely on highly conservative withdrawal times. With this new evidence, practitioners can better balance effective treatment of nitrate toxicity with responsible residue avoidance in food animals.
Article Discussed
In this episode of Diving Into Diets on Bovine Science with BCI, the experts discuss a 2025 meta-analysis comparing organic and inorganic trace mineral supplementation in beef cattle during preconditioning and feedlot receiving. They explain the biological differences between mineral sources and review results from about 20 studies included in the analysis. Overall, organic minerals showed a small improvement in average daily gain, but no effect on cattle morbidity. The discussion highlights that while organic minerals may provide slight performance benefits in certain situations, the overall effects are relatively small and context-dependent.
Article Discussed: HERE
This episode of After the Abstract reviews a 2025 study on managing Johne’s disease in beef cattle using different testing and culling strategies in a modeled 300-cow herd. The results showed that testing cows every six months reduced disease prevalence the most, but was the least profitable strategy, even compared with doing nothing. Testing every 24 months provided the best economic balance, lowering prevalence moderately while maintaining the highest net return. The discussion also emphasizes that the prevalence of Johne’s disease in purchased replacement cattle and strong biosecurity practices may influence herd outcomes more than frequent testing.
Article Discused: https://pubmed.ncbi.nlm.nih.gov/41472190/
In this episode of Herd Health, the experts review a 2025 study evaluating whether modified live virus (MLV) vaccines can be given at the time of CIDR placement for timed AI in beef cows. In previously vaccinated, multiparous cows about 80 days postpartum, administering an MLV vaccine at synchronization did not negatively affect estrus response, AI pregnancy rates, overall pregnancy rates, pregnancy loss, calving timing, or calf weaning weights. Total pregnancy rates were around 95%, with no significant differences between vaccinated and control groups. The findings suggest that giving an MLV vaccine at synchronization is safe in well-vaccinated adult cows, though results may not apply to naïve heifers.
Article Discussed
On this episode of Tox Talk, Dr. Brad White and Dr. Scott Fritz discuss a case where eight bred cows were moved into a barn ahead of a winter storm and were found dead the next morning. While initial concerns focused on the barn environment, testing revealed the cause was acute nitrate poisoning from newly introduced millet hay containing high nitrate levels. Nitrate toxicity can cause rapid death, often within hours, and may leave few obvious signs. This case is a reminder to consider what has changed when sudden losses occur, especially feed sources. Certain forages, including millet and other stress-grown crops, can accumulate nitrates, and toxicity persists after baling. Testing unfamiliar or newly purchased hay can help prevent devastating losses.
In this episode of Diving into Diets, the discussion examines how different phosphorus and calcium diets affect phosphorus retention, milk composition, calf growth, and bone status in beef cattle. While cows on lower-phosphorus diets maintained milk production and calf growth in the short term, they mobilized phosphorus from bone, unlike cows on high-phosphorus, high-calcium diets. The takeaway is that cows are resilient and can tolerate short-term deficiencies, but inadequate long-term mineral intake may eventually impair performance, underscoring the need for appropriate supplementation.
Article Discussed: https://era.dpi.qld.gov.au/id/eprint/14721/1/AN24216.pdf
This episode of Herd Health explores how cattle producers and veterinarians can choose the most effective estrus synchronization and fixed-time AI protocols for heifers and cows. Dr. Bob Larson explains that there is no single “best” protocol. Instead, the right choice depends on factors such as whether you are dealing with heifers or cows, time available, group size, handling logistics, and cost. The discussion highlights the roles of progesterone, GnRH, and prostaglandin, compares common protocols, and emphasizes using trusted resources such as the Beef Reproduction Task Force and working closely with veterinarians to ensure proper execution and consistent results.
Beef Reproduction Task Force
In this episode of About the Abstract, Dr. Brad White and Dr. Todd Gunderson discussed a study that tested whether water intake can predict bovine respiratory disease (BRD). The study’s main finding was that water intake decreased 1–2 days before BRD treatment or diagnosis. The study also found that the amount of water consumed mattered more than the number of visits or the time spent at the waterer. The cattle treated multiple times for BRD consistently drank less water than healthy cattle. The main takeaway from the study was that monitoring water intake per visit to the waterer is more important than monitoring cattle behavior.
Article Discussed: https://www.sciencedirect.com/journal/preventive-veterinary-medicine
On Dividing into Diets, Dr. Brad White and Dr. Philip Lancaster explore how a ruminant’s diet influences the production of volatile fatty acids (VFAs), such as acetate, propionate, and butyrate, created through the fermentation of carbohydrates and proteins in the rumen. They explain that different types of feed support different bacterial populations, shifting the balance of VFAs. For example, grain-heavy diets boost propionate levels, while high-forage diets favor acetate. Despite these shifts, overall animal efficiency depends more on the total amount of volatile fatty acids produced than on the specific proportions. The experts note that attempts to manipulate VFA ratios can be expensive and often yield only minor improvements in productivity.
On today’s episode of Herd Health, Dr. Brad White and Dr. Bob Larson discuss how to choose the best synchronization protocol for artificial insemination in cattle. They explain the differences between protocols for heifers and cows, including timing, hormone use, and management considerations. The discussion highlights the importance of resources like the Beef Reproduction Task Force website and factors such as chute time, cost, and herd size.
Episode Resource: https://beefrepro.org/
On Herd Health, Dr. Brad White and Dr. Bob Larson discuss a 2025 study in the Canadian Journal of Animal Science on factors influencing heifer replacement and cow-calf profitability. The study focused on cow feed efficiency, longevity, heterosis, and lifetime productivity. Key findings include the importance of longevity, with heifers staying longer in the herd being more profitable. Crossbreeding, particularly those with more heterosis, reduced costs. Residual feed intake (RFI) was crucial, with lower RFI cows being more efficient and cost-effective. The study used data from 2011 to 2018, accounting for economic fluctuations, and found no significant differences between breeds.
Article Discussed: https://www.researchgate.net/publication/385812533_Effects_of_cow_feed_efficiency_longevity_heterosis_and_lifetime_productivity_on_profitability_of_heifer_selection_and_cow-calf_operations
Dr. Brad White and Dr. Todd Gunderson discuss a study on bovine coronavirus and its role in respiratory disease in cattle. The study, published in Frontiers in Veterinary Science, used a challenge model with 15 challenge calves and six control calves. Results showed higher viral shedding in challenge calves. PCR detected bovine coronavirus in multiple tissues but not in the lungs or tracheobronchial lymph nodes. Histopathology scores indicated more pathology in challenge calves, but clinical signs were mild. The study suggests bovine coronavirus may play a role in mild respiratory disease but not in severe pneumonia, possibly acting as a co-factor for secondary infections.
Article Discussed: https://www.frontiersin.org/journals/veterinary-science/articles/10.3389/fvets.2022.878240/full
On this week’s episode of Diving into Diets Dr. Brad White and Dr. Philip Lancaster discuss a 2025 study on grazing behavior in cattle, focusing on factors like age, size, hide color, and forage quality. The study tracked 40 cows using GPS collars over three years, finding that older cows traveled further distances, possibly due to learning topography. Red cows traveled more in cold temperatures due to better heat retention from black hides. The study also noted that cows traveled further to high-quality forage areas, as measured by NDVI and IRG, and up slopes and to water sources. The study’s individual hypothesis testing approach limited the interpretation of confounding variables like production stage and weather.
Article Discussed: https://www.sciencedirect.com/science/article/abs/pii/S1871141325001258?via%3Dihub
Dr. Brad White and Dr. Bob Larson discuss the failure of passive transfer in beef herds, highlighting differences from dairy cattle. Risk factors included calves born to heifers, twins, and assisted births. Higher body condition scores in cows also correlated with lower IgG levels. The study emphasized the importance of colostrum intake, especially in high-risk situations. The discussion emphasizes the need for targeted management strategies in beef cattle.
Article Discussed: https://pmc.ncbi.nlm.nih.gov/articles/PMC2643452/
In About the Abstract, the experts discuss a study by Cordial and Carrie (2024) in the Journal of Animal Science, which compared the impact of metaphylaxis with Tulathromycin versus saline on high-risk beef stocker calves over 42 days. The study found that calves treated with Tulathromycin had higher average daily gain, especially in the first 14 days, and fewer treatments for respiratory disease. Culture results showed more bacteria in saline-treated calves at follow-up. Antimicrobial use was higher in the Tulathromycin group, but the number of regimens was similar. The study suggests that metaphylaxis may improve health and performance while managing antimicrobial resistance.
Featured Article: https://pubmed.ncbi.nlm.nih.gov/38126883
In this episode of BCI Cattle Chat, guest Dr. Cassandra Olds continues the discussion of Theileria, a tick- and fly-borne parasite affecting U.S. cattle herds. The team explains how it spreads from the East Coast westward, causes anemia-like symptoms, and persists for life in infected animals. They stress prevention through stress reduction, parasite control, and good nutrition, noting that no approved treatment exists. The conversation shifts to preparing heifers for breeding season, emphasizing pre-breeding exams, tracking weight and reproductive readiness, and managing nutrition to ensure early conception and lifelong productivity.
Dr Cassandra Olds Contact Information:
34A Waters HallManhattan KS 66506Phone: (785) 706-8599Fax: (785) 532-6232
colds@ksu.edu
In this Tox Talk episode, Dr. Brad White and Dr. Scott Fritz review a case involving six dead calves out of 38 fall-calving cow–calf pairs on pasture. The producer had not been checking the herd frequently, making the exact timeline of deaths unclear. With at least one calf estimated to have been dead for 4–5 days. They emphasize how decomposition, weather, and time since death affect necropsy value. Initial differential diagnoses focus on infectious causes and potential toxicities, given that only calves were affected.
Brad White and Dr. Bob Larson discuss a case where a client found an aborted fetus in their herd. Dr. Larson suggests identifying the aborting animal, collecting samples from the fetus, including the placenta, lung, liver, and brain, and holding them for further analysis. He emphasizes the importance of understanding the herd’s history, including the age and origin of the cows, and potential causes like Neospora, IVR, BVD, and feed contamination.
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