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The Science of Skin

Author: A Science of Skincare Podcast

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The Science of Skin is a podcast for those who want to be in-the-know about what’s trending, and what’s next in topical skincare.  Hosts  Dr. Patti Farris and Dr. Ted Lain are board certified dermatologist, recognized experts in topical skincare and co-founders of the Science of Skin Summit. In each episode, The Science of Skin will give you an insider’s view of the skincare industry.  You will hear from research scientists, formulators, and leading physician experts on how products are developed, tested, and used to treat medical and cosmetic patients.  


So, if you’re interested in a behind the scenes look at what makes the skincare industry tick, subscribe to The Science of Skin today. Thanks for listening!


 


You can slo find us on YouTube: https://www.youtube.com/@scienceofskinpodcast


Disclaimer: This podcast is not intended to provide diagnosis, treatment, or medical advice. Content provided in this podcast is for educational purposes only. Please consult with a physician regarding any health-related diagnosis or treatment.

104 Episodes
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In this episode of the Science of Skin podcast, Dr. Patti Farris and Dr. Ted Lain explore the history and significance of Cetaphil, a legendary brand in dermatology. They discuss the origins of its key ingredient, cetal alcohol, and its role in skincare formulations, particularly for sensitive skin. The conversation highlights the brand's evolution, including recent reformulations that enhance its effectiveness while addressing modern skincare needs. The hosts emphasize the importance of barrier function and the impact of inflammation on skin health, particularly for patients with sensitive skin. They also preview future discussions on the science behind Cetaphil products. Disclaimer: This podcast is not intended to provide diagnosis, treatment, or medical advice. Content provided in this podcast is for educational purposes only. Please consult with a physician regarding any health-related diagnosis or treatment.See omnystudio.com/listener for privacy information.
In this episode of The Science of Skin, Dr. Elke Grönniger  from Beiersdorf discusses her research on epigenetics and cellular rejuvenation, focusing on dehydromyricetin's role in demethylating the epigenome. The conversation highlights the shift towards preventative skincare, targeting the root causes of aging, and the importance of understanding the hallmarks of aging for future product development.   Disclaimer: This podcast is not intended to provide diagnosis, treatment, or medical advice. Content provided in this podcast is for educational purposes only. Please consult with a physician regarding any health-related diagnosis or treatment.See omnystudio.com/listener for privacy information.
In this episode of the Science of Skin podcast, Dr. Ted Lain interviews Dr. Hassan Galadari, a renowned dermatologist from Dubai. They discuss the journey of hosting the World Congress of Dermatology, the evolution of injectables in aesthetic medicine, and the significance of polynucleotides and PDRN in skin rejuvenation. The conversation also touches on the role of epigenetics in longevity and the unique experience of practicing dermatology in Dubai, a city known for its diverse population and rapid development. Takeaways Dr. Galadari is a leader in injectables and aesthetic dermatology.Hosting the World Congress requires international support and persistence.Injectables are shifting towards biostimulatory fillers for natural results.Polynucleotides and PDRN have unique mechanisms in skin rejuvenation.Inflammation plays a significant role in the aging process.GLP-1s may enhance skin quality while reducing inflammation.Dubai's diverse population enriches the practice of dermatology.International conferences foster valuable connections and knowledge exchange.Longevity in dermatology involves optimizing cellular function.The aging process requires a multifaceted approach to treatment. Disclaimer: This podcast is not intended to provide diagnosis, treatment, or medical advice. Content provided in this podcast is for educational purposes only. Please consult with a physician regarding any health-related diagnosis or treatment.See omnystudio.com/listener for privacy information.
In this milestone 100th episode of the Science of Skin podcast, Dr. Ted Lain and Dr. Patti Farris reflect on their journey, discussing impactful studies in dermatology, the importance of skincare for menopause, the definition of skin quality, and the integration of Eastern and Western medicine. They also explore the gut-skin connection, the issue of human trafficking in dermatology, and highlight pioneers in the field. The episode concludes with insights into the business of skincare and a heartfelt thank you to their loyal listeners. Takeaways This is episode number 100 for the science of skin podcast.We have a very loyal following.The antioxidant study debunked previous misconceptions.C.E. Ferulic remains foundational in skincare.The sandwich technique affects retinoid efficacy.HRT is crucial for managing menopause symptoms.Skin quality metrics are essential for patient satisfaction.Integrating Eastern medicine can enhance treatment outcomes.The gut-skin connection is scientifically supported.Human trafficking awareness is vital for dermatologists. DISCLAIMER: This podcast is not intended to provide diagnosis, treatment, or medical advice. Content provided in this podcast is for educational purposes only. Please consult with a physician regarding any health-related diagnosis or treatment.See omnystudio.com/listener for privacy information.
Dr. Ted Lain sits down with Tom Allison to uncover the origin story of CeraVe—from its pharmaceutical roots to becoming one of the most dermatologist-recommended skincare brands in the world. They explore the science behind ceramides and MVE technology, the role of dermatologists in product development, and key lessons in building a brand that truly serves patients. A must-listen for clinicians, skincare professionals, and anyone curious about the intersection of science, skin health, and smart business. To watch this and other episodes, be sure to check out our YouTube page  Disclaimer: This podcast is not intended to provide diagnosis, treatment, or medical advice. Content provided in this podcast is for educational purposes only. Please consult with a physician regarding any health-related diagnosis or treatment.See omnystudio.com/listener for privacy information.
In honor of the start of Black History Month, Dr. Patti Farris and Dr. Heather Woolery-Lloyd delve into the complexities of hair care for textured hair. They discuss the historical significance of Madam C.J. Walker, the physiological differences in hair types, and the unique hair care routines required for textured hair. The conversation also covers the risks of over-processing, the importance of finding the right stylist, and the challenges of conditions like traction alopecia and CCCA. Additionally, they address recent studies linking hair treatments to cancer, emphasizing the need for careful interpretation of research findings. Takeaways Madam C.J. Walker was a pioneer in hair care marketing.Textured hair has unique physiological characteristics.Washing textured hair should be done every one to two weeks.Heat can cause significant damage to textured hair.Finding a knowledgeable stylist is crucial for hair health.Traction alopecia is a common issue in textured hair.CCCA can be treated effectively if caught early.Shampoo choices should be personalized for textured hair.Recent studies on hair treatments and cancer need careful interpretation.Education on textured hair care is essential for dermatologists. DISCLAIMER: This podcast is not intended to provide diagnosis, treatment, or medical advice. Content provided in this podcast is for educational purposes only. Please consult with a physician regarding any health-related diagnosis or treatment.  See omnystudio.com/listener for privacy information.
In this episode of the Science of Skin podcast, Dr. Ted Lain interviews Dr. Matt Zirwas, a leading expert in dermatology, focusing on the latest advancements in treatments for atopic dermatitis and psoriasis. They discuss the potential of new drugs targeting the OX40 pathway, innovative drug delivery methods, and the emergence of highly effective oral therapies for psoriasis. The conversation highlights the evolving landscape of dermatological treatments and the exciting prospects for long-term patient outcomes. In this conversation, Dr. Zirwas and Dr. Lain discuss various dermatological treatments, focusing on drug administration, bioavailability, and the efficacy of new medications for conditions like hidradenitis suppurativa and chronic spontaneous urticaria. They explore the implications of PDE4 inhibitors, the challenges of assessing treatment outcomes, and the importance of pain management in patient care. The discussion highlights the evolving landscape of dermatology and the significance of clinical trials in advancing treatment options. To watch this and other episodes, be sure to check out our YouTube page  Takeaways: New drugs targeting the OX40 pathway may revolutionize treatment for atopic dermatitis.Innovative drug delivery methods could lead to less frequent dosing for patients.The potential for long-term remission in atopic dermatitis is an exciting prospect.Adverse events in new drugs may correlate with better efficacy.Oral therapies for psoriasis are emerging as a new class of effective treatments.The efficacy of new oral drugs may surpass traditional biologics.The importance of understanding pharmacokinetics in drug efficacy is highlighted.The development of advanced systemic therapies is changing the landscape of dermatology.The future of psoriasis treatment may include drugs that effectively target both skin and joint disease. Drug bioavailability is significantly affected by food intake.PDE4 inhibitors show promise in improving various conditions.Cognitive benefits have been observed with PDE4 inhibitors.Pain management is a critical endpoint in HS treatment.Assessing HS severity is challenging for investigators.New treatments are emerging for chronic spontaneous urticaria.Patient satisfaction is essential in evaluating treatment success.Innovative drugs are changing the landscape of dermatology.Clinical trials are crucial for advancing treatment options.Understanding patient needs is key to effective care. Disclaimer: This podcast is not intended to provide diagnosis, treatment, or medical advice. Content provided in this podcast is for educational purposes only. Please consult with a physician regarding any health-related diagnosis or treatment.  See omnystudio.com/listener for privacy information.
In this episode of the Science of Skin podcast, Dr. Ted Lain and Dr. Patti Farris discuss emerging skincare trends for 2026, while also reflecting on practices from 2025 that they hope will fade away. They express their disdain for certain ingredients like beef tallow and complicated skincare regimens, advocating instead for simplicity and effectiveness in skincare routines. The conversation shifts to the rise of regenerative ingredients and the importance of personalized skincare, emphasizing the need for dermatologists to remain integral in skincare consultations despite the growing influence of AI in the field. The hosts delve into the advancements in sunscreen technology, particularly a new UVA filter expected to be approved soon, and the potential for DNA repair innovations in skincare. They also touch on the increasing importance of supplements in skincare, the impact of hormonal changes on skin health, and the need for education around teenage skincare. The episode concludes with a call for dermatologists to embrace their role as skincare experts, ensuring patients receive the best advice amidst the overwhelming information available online. To watch this and other episodes, be sure to check out our YouTube page  Takeaways Out with the complicated, in with the curated.Don't underestimate the value of a dermatologist consultation.Regenerative ingredients can reverse skin damage.2026 will see a rise in personalized skincare.The microbiome plays a crucial role in skin health. Disclaimer: This podcast is not intended to provide diagnosis, treatment, or medical advice. Content provided in this podcast is for educational purposes only. Please consult with a physician regarding any health-related diagnosis or treatment.  See omnystudio.com/listener for privacy information.
Dr. Patti Farris sits down with Brit Fallon from NewBeauty Magazine. They discuss the influence of social media on skincare, the distinction between skincare and dermfluencers, the ethical role of board-certified dermatologists, and emerging trends like regenerative skincare and AI in personalized beauty. To watch this an other episodes, be sure to check out our YouTube page  Disclaimer: This podcast is not intended to provide diagnosis, treatment, or medical advice. Content provided in this podcast is for educational purposes only. Please consult with a physician regarding any health-related diagnosis or treatment.See omnystudio.com/listener for privacy information.
Dr. Patti Farris hosts Sarika Diaz and Renee Rouleau to discuss their roles at the Science of Skin Summit 2025. They highlight the importance of community, relationships, and education in skincare, particularly regarding acne management and the collaborative efforts between estheticians and physicians for effective treatment and advanced services. To watch this an other episodes, be sure to check out our YouTube page  Disclaimer: This podcast is not intended to provide diagnosis, treatment, or medical advice. Content provided in this podcast is for educational purposes only. Please consult with a physician regarding any health-related diagnosis or treatment.See omnystudio.com/listener for privacy information.
In this episode of the Science of Skin podcast, Dr. Ted Lain and Dr. Andrew Alexis discuss trifarotene Cream, a novel fourth-generation retinoid. They explore its mechanism of action, clinical efficacy, and the importance of addressing not only acne lesions but also the psychosocial impacts of acne on patients. The conversation delves into the results of phase three and phase four clinical trials, highlighting ttrifarotene's effectiveness in treating both acne and post-inflammatory hyperpigmentation. The episode emphasizes the need for dermatologists to consider the entire acne journey and the long-term benefits of retinoid therapy for their patients. To watch this an other episodes, be sure to check out our YouTube page  Takeaways: Trifarotene is a novel fourth-generation retinoid. It binds preferentially to the RAR gamma receptor, enhancing its efficacy. Trifarotene not only treats acne but also improves scarring and pigmentation. Clinical trials show significant efficacy in both facial and truncal acne. The psychosocial impact of acne is profound and long-lasting. Retinoids are foundational in acne treatment regimens. Patients benefit from continued use of retinoids beyond acne clearance. Phase four studies demonstrate trifarotene's effectiveness in reducing atrophic scars. Acne-induced hyperpigmentation is a significant concern that needs addressing. Education about retinoids can improve patient compliance.See omnystudio.com/listener for privacy information.
In this episode of the Science of Skin podcast, Dr. Ted Lain interviews Dr. Scott Drew, a dermatologist and philanthropist, about his work with the Power of a Nickel, a nonprofit organization dedicated to providing healthcare to underserved populations around the world. They discuss the mission of the organization, the cultural challenges faced during medical missions, the importance of continuity of care, and the logistics of organizing these trips. Dr. Drew shares personal anecdotes and insights from his experiences, emphasizing the need for open-mindedness and cultural sensitivity in global health initiatives. To learn more about Power of a Nickel, please click the link: https://powerofanickel.org/ To watch this an other episodes, be sure to check out our YouTube page  Takeaways The Power of a Nickel focuses on providing healthcare to underserved populations.Cultural understanding is crucial when practicing medicine in different countries.Medical students gain invaluable experience through international missions.Dermatology often addresses common health issues exacerbated by lack of resources.Volunteers do not need specialized training but should be open-minded.Continuity of care is essential for effective healthcare delivery.Living conditions during medical missions can vary significantly.Volunteers are provided with necessary supplies and support.Community engagement is key to successful healthcare initiatives.The organization fosters a multidisciplinary approach to healthcare. Disclaimer: This podcast is not intended to provide diagnosis, treatment, or medical advice. Content provided in this podcast is for educational purposes only. Please consult with a physician regarding any health-related diagnosis or treatment.See omnystudio.com/listener for privacy information.
In this episode, Dr. Patti Farris and Dr. Ted Lain discuss their experiences at the A4M Longevity Fest in Las Vegas, highlighting the growing interest in anti-aging medicine and longevity. They delve into various topics including female health, hormonal balance, the importance of exercise and muscle mass, innovations in personalized medicine, the microbiome's role in aging, the rise of peptides, and nutritional insights for longevity. The conversation also covers emerging technologies and products seen at the exhibit hall, concluding with a look at the future of longevity medicine. To watch this an other episodes, be sure to check out our YouTube page  Takeaways The A4M Longevity Fest showcased a significant interest in anti-aging medicine.Female longevity and hormonal health are critical areas of focus.Exercise and maintaining muscle mass are essential for longevity.Personalized medicine is evolving with advancements in epigenetics.The microbiome plays a crucial role in aging and health.Peptides are gaining traction in longevity treatments.Nutrition, particularly protein intake, is vital for long-term health.The exhibit hall featured numerous innovative products and technologies.Liquid biopsies are becoming a mainstream tool for early detection.Longevity medicine is increasingly becoming a part of mainstream healthcare. Disclaimer: This podcast is not intended to provide diagnosis, treatment, or medical advice. Content provided in this podcast is for educational purposes only. Please consult with a physician regarding any health-related diagnosis or treatment.See omnystudio.com/listener for privacy information.
Dr. Patti Farris and Dr. Saranya Wyles discuss advancements in dermatology, focusing on regenerative medicine's role in wound healing and skin aging. They explore exosomes' potential for repair, the distinction between regenerative medicine and longevity science, and the importance of maintaining skin health alongside lifespan through innovative skincare approaches. To watch this an other episodes, be sure to check out our YouTube page  Disclaimer: This podcast is not intended to provide diagnosis, treatment, or medical advice. Content provided in this podcast is for educational purposes only. Please consult with a physician regarding any health-related diagnosis or treatment.See omnystudio.com/listener for privacy information.
In this episode of the Science of Skin podcast, Dr. Ted Lain interviews Tara Loftis, the Global President for Dermatological Skincare at Galderma. They discuss Tara's impressive career journey in the skincare industry, her insights on consumer needs, and the importance of sensitive skin research. The conversation also explores future trends in skincare, emphasizing the shift towards genuine skin health and the democratization of skincare products. Tara shares her passion for innovation and the role of dermatologists in shaping the future of skincare. To watch this an other episodes, be sure to check out our YouTube page  Takeaways Tara Loftis oversees four significant skincare brands at Galderma.Benzac has a strong presence in international markets, especially among Gen Z.Elastin Skincare has seen incredible advances under Dr. Widgerow's leadership.Consumer insights drive product development at Galderma.Sensitive skin is a growing concern, with 70% of people self-identifying as having it.Galderma's Sensitive Skin Faculty focuses on research and education.The skincare industry is seeing a shift towards genuine skin health.Gen Z is becoming increasingly skincare fluent and aware.The democratization of skincare allows access to high-quality products for everyone.Tara emphasizes the importance of being consumer-obsessed in product development. Disclaimer: This podcast is not intended to provide diagnosis, treatment, or medical advice. Content provided in this podcast is for educational purposes only. Please consult with a physician regarding any health-related diagnosis or treatment.See omnystudio.com/listener for privacy information.
Join Dr. Patti Farris as she welcomes Zubin Meskenpush, President and COO of Sente, to the 2025 Science of Skin Summit. Discover Sente’s revolutionary HERO technology featuring their proprietary Heparan Sulfate Analog (HSA), reshaping skincare with enhanced hydration, inflammation control, and cellular health. Dive into the science behind their new antioxidant serum, Defense C, which blends HSA with a powerful form of Vitamin C. Learn how this innovation protects against environmental stress and aging, validated by clinical and ex vivo studies. Tune in for insights on how Sente’s cutting-edge solutions are shaping the future of skincare. Disclaimer: This podcast is not intended to provide diagnosis, treatment, or medical advice. Content provided in this podcast is for educational purposes only. Please consult with a physician regarding any health-related diagnosis or treatment. Follow and listen to The Science of Skin Podcast:  YouTube: https://www.youtube.com/@scienceofskinpodcast Apple: https://podcasts.apple.com/us/podcast/skincare-confidential/id1664286292 Spotify: https://open.spotify.com/show/49NtbRxb32CJu2XtSV6tso Amazon Music: https://music.amazon.com/podcasts/7de48e5e-f450-466b-a0f4-f2275b67757f/skincare-confidential iHeart: https://www.iheart.com/podcast/269-skincare-confidential-269540115/ Audacy: https://www.audacy.com/podcast/skincare-confidential-4398fSee omnystudio.com/listener for privacy information.
Dr Lain interviews the founder of AO2 Skin, Rob Solomon, along with the Chief Medical Officer Dr Vivian Bucay. AO2 employs nanobubble technology to deliver pure oxygen into the skin. We discuss the origins of the technology and brand with Rob, then turn to Dr Bucay to understand how this technology reduces redness, fights acne, and supports a healthy microbiome. To watch this an other episodes, be sure to check out our YouTube page  Disclaimer: This podcast is not intended to provide diagnosis, treatment, or medical advice. Content provided in this podcast is for educational purposes only. Please consult with a physician regarding any health-related diagnosis or treatment.See omnystudio.com/listener for privacy information.
We interview Dr Rishabh Kala, Director of Advanced Technologies for Skin Biology at the Estee Lauder Companies.  With a PhD in Epigenetics, Dr Kala shares his expertise on the dual functions of the Sirtuin family, focusing primarily on their performance within mitochondria to extend cellular longevity.  Dr Kala was interviewed live at the 2025 Science of Skin Summit. To watch this an other episodes, be sure to check out our YouTube page  Disclaimer: This podcast is not intended to provide diagnosis, treatment, or medical advice. Content provided in this podcast is for educational purposes only. Please consult with a physician regarding any health-related diagnosis or treatment.See omnystudio.com/listener for privacy information.
In this episode, Dr. Ted Lain and Dr. Patti Farris discuss the highlights from their recent series, 'Skincare Through the Ages.' They explore foundational skincare regimens, the importance of diversity in skincare research, unique skincare needs for men, and effective solutions for menopause-related skin changes. The conversation emphasizes practical advice, the significance of retinol, and the democratization of skincare products for all skin types. To watch this an other episodes, be sure to check out our YouTube page  A big thank you to our sponsor Neutrogena® To learn more about the products discussed in this episode, please visit: Dedicated to Dermatology Professionals | NeutrogenaMD® Takeaways Foundations of a good skincare regimen include cleanse, moisturize, and protect.The best sunscreen is the one the patient will use consistently.Diversity in skincare research is crucial for effective product development.Aging occurs in steps, not gradually, highlighting the need for early intervention.Retinol remains the gold standard in anti-aging skincare.Men's skincare requires a different approach due to unique skin characteristics.Moisturization and exfoliation must be balanced, especially in post-menopausal patients.The water cream is highly effective for hydration in older patients.Acne patches can help prevent picking and improve healing.Skincare education should meet patients where they are, fostering ownership of their routines. Disclaimer: This podcast is not intended to provide diagnosis, treatment, or medical advice. Content provided in this podcast is for educational purposes only. Please consult with a physician regarding any health-related diagnosis or treatment.See omnystudio.com/listener for privacy information.
In this episode, Dr. Patti Farris is joined by dermatologists Dr. Mona Gohara and Dr. Kavita Mariwalla to discuss the impact of menopause on skin health. They explore common skin concerns during menopause, effective skincare recommendations, the importance of retinol and sunscreen, and the controversial topic of topical estrogens. The conversation emphasizes the need for accessible skincare solutions and the importance of understanding the changes that occur in the skin during this life stage. To watch this an other episodes, be sure to check out our YouTube page  A big thank you to our sponsor Neutrogena® To learn more about the products discussed in this episode, please visit: Dedicated to Dermatology Professionals | NeutrogenaMD® Takeaways Menopause is a significant topic in medicine and skincare.Common skin concerns during menopause include dryness, dullness, and sensitivity.Retinol remains the gold standard in skincare for aging skin.Daily sunscreen use is crucial for skin protection, regardless of the weather.Neutrogena's Hydro Boost line is effective for post-procedure care.Topical estrogens are still under research and not widely recommended for facial use.Retinol provides multiple benefits, including collagen production and skin tone improvement.Patients should be educated on the importance of skincare routines during menopause.Accessibility to effective skincare products is essential for all women.Simplicity in skincare routines can help manage the complexities of menopause. Disclaimer: This podcast is not intended to provide diagnosis, treatment, or medical advice. Content provided in this podcast is for educational purposes only. Please consult with a physician regarding any health-related diagnosis or treatment.See omnystudio.com/listener for privacy information.
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