In Search of Insight

Peruvian Black Maca | Capturing the Magic of the Andes With ScienceMaca has been used as a food source and supplement for thousands of years, but has been steadily gaining popularity amongst fitness enthusiasts and biohackers in recent years. Emiel and Erika take a dose of Nootropics Depot’s new Peruvian Black Maca powder and discuss the mechanisms of action responsible for its calming, mood-lifting, and libido-enhancing effects. Because of Maca’s growing popularity, sourcing quality Maca is more important than ever! Nootropics Depot has combined high quality gelatinized Maca with our Maca extract (5% macamides) and horseradish root powder, which work synergistically to strengthen the calming benefits of Maca. Emiel discusses the neuroscience behind maca’s effects, including how it works on cannabinoid and TRPA receptors to produce subtle stimulation, as well as how the fibers and starches in maca aid in healthy digestion and satiation. Erika and Emiel mix the Peruvian Black Maca powder with Infinigreens into a daily drink taken after breakfast, which provides them with energy, focus, and genuine fullness for the first half of the day. Want to learn more about our optimized and improved Peruvian Black Maca powder? Tune into the podcast on Tuesday September 2nd at 10:00 AM MST.

The Ultimate Tongkat Ali StackIn this podcast episode, we discuss the role of testosterone in muscle building, why men and women can both benefit from Eurycomax, and the perceptible confidence boosting effects of a single dose of Eurycomax! Emiel and Erika break down the science behind our optimized Tongkat Ali stack and how the combination of Tongkat Ali extracts, Horny Goat weed, Mucuna Puriens, Boron and Iodine can help you reach your fitness goals. If you are serious about reaching your fitness goals with high quality natural supplements, tune into this podcast and learn about the game changing and laser-focused ingredients in the Eurycomax stack. Podcast Chapters0:00 Introduction6:00 Taking EurycoMAX9:35 What’s Causing the Benefits? Cold water ultrasonic extract17:09 What are the pros and cons of Tongkat Ali?26:00 Why A Single Dose is Enough!27:45 Dopamine, Testosterone30:33 Ingredient Round Up39:52 Checking in On Perceptible Effects45:32 Sex Binding Hormone Globulin - Free Testosterone46:00 Boron Increases Free Testosterone49:40 Iodine Balances the Stack - Thyroid Regulation56:56 Motivation Effects of Eurycomax1:06:29 Balancing Estrogen Synthesis - Tongkat Ali + Icariin1:10:44 Testosterone Benefits of Eurycomax1:14:13 Mucuna Puriens - Testosterone and Dopamine Benefits1:16:00 Icariin Balances Estrogen and Testosterone1:18:00 Dosages of the Eurycomax Stack Ingredients1:19:20 Tongkat Ali of the Highest Quality

The First Real Ecklonia Cava on the Market?

Time for a Big Change...Emiel and Erika take you on a journey through temperate regions in the northern hemisphere, exploring the nootropic, spiritual, culinary, and medicinal uses of Lion’s Mane mushroom through time! Tune into the podcast and learn more about:✔️ Monks in Japan that have been using Lion’s Mane for centuries✔️ Relaxing and neuroprotective benefits of fruiting body and mycelium extracts✔️ Erinamax, the first lab-test verified liquid culture mycelium to contain Erinacine A✔️ New Directions in Erinacine and Lion’s Mane researchPodcast Chapters0:00 Lion’s Mane Use in Japan, China, Northern Hemisphere6:32 Hericium Erinaceus - Comparing Erinaceus to other Species7:30 Hericium Corraloides11:00 Tasting Lion’s Mane Mushroom RAW12:20 Southwest Mushrooms19:00 The Premium Price of Lion’s Mane23:43 Saprophyte - how does a Lion’s Mane mushroom grow?26:55 Forest Farming29:33 Fruiting Body vs. Mycelium Lion’s Mane37:41 I’m Feeling Something! Perceptible benefits of RAW Lion’s Mane46:31 Want to add Lion’s Mane to your Daily life?49:50 Amsterdam’s Noordermarkt51:47 Mushroom Magic Coffee Latte53:07 Ancient Wisdom - Feeling Perceptible BenefitsFollow Us on Social Mediahttps://www.instagram.com/insearchofinsight/https://www.reddit.com/r/NootropicsDepot/

Jungle To The Lab | The Ethnobotanist Life w/ Kerry Hughes "Ethnobotany is the study of the relationship between humans and plants." - Kerry Hughes Meet Kerry Hughes, ethnobotanist and author, and an inspiring member of Nootropics Depot's scientific advisory board. Kerry joins the podcast to discuss her background and passions as an ethnobotanist, and to share practical tips for connecting with the healing power of plants in our everyday lives, through supplements, food, incense, and spending time in nature. Chapters 0:00 Introducing Kerry Hughes, Ethnobotanist 1:17 What is an Ethnobotanist? 3:08 Taking Erinamax, Tiger Milk + Cognance from the ND Catalogue 4:21 Popping Pills - Ethnobotany style 5:55 Effectiveness of Quick-Dissolve Cognance vs. Cognizance capsules 10:14 The Lack of Bitter Compounds in Our Foods 12:18 Bitter Sensors in Our Digestive Tract 18:03 Madronho 20:41 Herbaviore - ?? 23:30 Bitter Compounds Regulate Blood Sugar - GLP1 Agonism 25:35 Biodiversity - We Don’t Save What We Don’t Value 27:45 California - LA Fires, Climate Crisis, Land Management 28:13 Cattle Grass 31:38 Gulf of Mexico - Hating on Swamps 35:25 Rewilding 37:05 Effects of Erinamax and Cognance 38:15 Experiential Accounts of Supplements 44:50 Being Mindful of Safety with Extracts - Purity 46:17 The Dose is the Poison 51:25 What’s In Your Garden? 51:45 The Squarest Ethnobotanist You’ll Ever Meet 55:55 Biodiversity 58:40 Regenerative Certification 1:01:55 Natural Wineries 1:02:17 Wild Yeast in Geuze and Lambiek 1:03:42 Plants are Sentient Beings 1:05:15 A World without Opiates 1:07:25 Use of plants, music, nature 1:10:25 Connection - Essential for Human Health

At Nootropics Depot, we're committed to raising the standards of the supplement industry through rigorous lab testing and transparency. This month, we spoke with Greg Doucette, IFBB Pro bodybuilder and founder of HTLT supplements, about the Turkesterone controversy that raised significant concerns within the bodybuilding community in 2022. Greg is known for his impressive YouTube following and bold personality - not to mention his physique. When Nootropics Depot tested Greg’s product, Turk Builder, and found it didn’t meet its claimed Turkesterone content, Greg chose to address the issue and take corrective action. In this podcast, we share lab results from Turkesterone products across the market, including those from HTLT's Turk Builder Max. Join us as we discuss the importance of integrity and quality in the supplement industry and explore the science behind these findings. This is an important step towards greater transparency—tune in to learn more! Chapters 0:00 Introduction 3:22 Turkesterone - Nootropics Depot Starts Asking Questions 4:30 HTLT - Fails Turkesterone Testing, Scandal Insues 5:45 Nootropics Depot Wants To Help Companies Improve 6:39 Turkbuilder Was a Fraud?! 7:50 FINALLY Greg Feels Vindicated 9:28 HTLT Thought They Were Doing The Right Thing 12:22 HPLC - High Performance Liquid Chromatography 15:34 TurkMax and TurkBuilder are VERIFIED PURE 19:18 Companies are Buying Fake Turkesterone and Profiting 21:55 How Did Greg Discover Turkesterone? Greg Meets Marwan 25:50 Difference Between Chinese and Uzbek Turkesterone 28:00 Turk Allows You To Feel More Aggression and Train Harder 28:39 Reselling Turkbuilder - A Second Chance 30:24 Everyone Wants A Mechanism of Action?! 34:24 Ecdysterone vs. Turkesterone Ratio 38:10 Ensuring Product Quality - For the Meatheads 38:28 Turkesterone is a Product that Can Make You Better 43:00 Researchers Aren’t Always Transparent 44:30 Quoting Bad Studies - How To Prove Identity and Purity? 49:00 TurkBuilder Uses Turkesterone as a Quality Control Point 51:45 Comparing TurkBuilder, TurkMax, and Beta Ecdysterone ND 55:58 Suppliers Lying and Spiking Products 57:30 Do It Right TWICE 59:50 Expedition to Uzbekistan 1:03:27 Terroir within Supplements - Ingredients and The Elements 1:08:30 Tasting Compounds - Can You Eat Ajuca Turkistanica Raw? 1:09:55 - Other Ecdysterone Compounds 1:12:14 Thank You To HTLT Partners in Uzbekistan 1:18:55 Snake Oil - The Real Story 1:20:00 What’s your favorite exercise in the gym? 1:27:25 Mr. Happy Stack 1:33:50 Requiem For A Dream? 1:38:06 I Feel Vindicated

Identity Crisis | Adulteration In The Supplement Industry In this new episode, Emiel u/Pretty-Chill and Erika welcome Ellie, Nootropics Depot’s new Science Director. Emiel, Ellie, and Erika discuss why it's essential to lab test supplements for identity and purity, and what this means for consumers. There are way too many products on the market that don’t contain the ingredients they claim to, and this is a serious problem. In this podcast, you’ll learn about how identity testing works, why Nootropics Depot is so passionate about quality, and why Ellie is thrilled to be a part of our lab and marketing team at Nootropics Depot! Happy listening! Chapters 00:00 Introduction 1:39 Benefits of Stacking Mushroom Magic Matcha & Cognance 12:00 Botanical Origin Story 17:13 Identity Testing - Watercress 27:00 HPLC Plates for Identity Testing 31:40 Testing for Erinacine A 36:00 Science Communication 50:46 Reference Standards for Erinacine A

RELIEVEX | A Vendetta Against Pain This month’s podcast is all about pain - and our new pain management stack, Relievex! Buy Relievex from Nootropics Depot https://nootropicsdepot.com/relievex-capsules/ We at Nootropics Depot have a vendetta against pain, and Relievex is our secret weapon that provides physical and mental relief from pain. In this podcast, product specialist Emiel and podcast host Erika discuss the question “What is pain?” and what we can do to address it. Naturally, we discuss why taking Relievex is a great way to manage pain as needed, or on a daily basis. Chapters 0:00 Introduction 1:05 Taking a Full Dose of Relievex - what are the benefits? 5:48 Why take Relievex? Inspiration behind the product 10:26 The difference between perception of pain vs. healing the source 16:04 Discussing the source of Pain (injury, inflammation, stress, lack of sleep) 20:08 Breaking Down the Ingredients of Relievex 22:49 Ingredients & Effects - Kava 26:41 Ingredients & Effects - Lemon Balm 27:54 Ingredients & Effects - Maca 33:32 Ingredients & Effects - Tetrahydromagnolol 35:25 Ingredients & Effects - Palmitoylethanolomide 38:05 Ingredients & Effects - Supercritical Boswelia 40:22 Ingredients & Effects - Ginger

NEW PRODUCTS! InfiniLyte & BerbeLean Learn about Nootropics Depot's new fitness supplements, InfiniLYTE and BerbeLEAN in this video! Our product specialist Emiel and In Search of Insight podcast host Erika break down the benefits, ingredients, and inspiration behind our two newest supplements. 00:00 Introduction 00:27 InfiniLyte - Comprehensive Electrolyte 42:20 BerbeLean - Berberine Stack

Video Episode | BERBERINE | Live Leaner, Happier, Longer This podcast episode is about Berberine, the most effective supplement for weight loss and body recomposition. In this new episode you’ll learn how Berberine supports glucose metabolism, gut health, and our daily energy levels! Try Berberine from Nootropics Depot! https://nootropicsdepot.com/berberine-hcl-silymarin-tablets/ https://nootropicsdepot.com/berberine-phytosome-capsules-550mg/ Chapters 0:00 Introduction - Berberine Helps Manage Glucose Metabolism 3:00 Glucose Metabolism 5:20 Visceral Adipose Tissue & Testosterone 7:20 Berberine + Silymarin versus Berbevis (Berberine Phytosome) 8:45 Dosing Berberine + Silymarin After a Light Lunch 10:30 Sigma 1 - Stimulation and Energy Benefits from Berberine 12:50 Dosing Berberine + Silymarin versus Berberine Phytosome 13:45 GLP1 and Hunger Satiety 18:26 How does GLP1 Work? 19:22 How Berberine Supports Healthy Bacteria - Akkermansia muciniphila 20:25 Bioavailability Concerns - Berberine Silymarin vs. Berberine Phytosome 32:25 Berberine and Curcumin as Biofilm Disruptors 37:49 Berberine & AMPK Activation 45:58 Why Berberine vs. C3G or Black Ginger? 53:11 Mind + Body Connection - Gut Health + Mood 56:02 AMPK Activation + Mood 58:45 Berberine’s Effects on Neurotransmitters

Video Episode | BLACK GINGER | Bigger, Harder, Happier A new podcast episode from In Search of Insight is here! This podcast episode is about our new Black Ginger extract. Black Ginger is a game-changing supplement for burning fat, achieving your fitness goals, boosting libido and sexual performance, increasing motivation and lifting mood. In this podcast, Product Specialist Emiel and podcast host Erika discuss the science behind Black Ginger’s fat-burning and libido-boosting qualities. We explain key mechanisms for Black Ginger’s benefits including thermogenesis, body recomposition, and the role of brown fat cells. We also explore the sexual function benefits of Black Ginger, namely its PDE5 inhibition which increases blood flow, which allows for better erections and arousal. Adding to these benefits, Black Ginger has a unique method of lifting our mood and motivation through it’s modulation of neurotransmitter release and processing. Buy Black Ginger from Nootropics Depot https://nootropicsdepot.com/black-ginger-extract-capsules/ Podcast Chapters 0:00 Introduction + Double Dose of Black Ginger 4:34 Black Ginger Benefits 5:00 Fitness + Endurance Benefits of Black Ginger 10:47 Fat Burning + Body Recomposition Benefits 19:21 Muscle Protein Synthesis Pathways 23:11 Sitruin 1 Activation  28:45 Summary of Fitness Benefits + Pathways 30:30 Sexual Function + Libido Benefits 31:59  PDE5 Inhibition 39:25 Neurotransmitter Release Process 43:42 Summary of Libido Benefits 49:12 Perceptible Benefits of Black Ginger 53:15 Stacking Black Ginger

Mr. Happy | The Next Generation 1:27 Longecity Forum - Early Nootropics Community 3:20 Foundations of Supplement Experimentation 7:50 Shifting Towards Minerals and Micronutrients 15:30 Origins of Nootropics Depot + Our Purity Standards 18:31 Vendors and Sourcing 26:30 Lion’s Mane, Reishi, Mushroom Research 28:20 Cultivating Lion’s Mane 35:50 Reishi + Immune Response 39:40 Joshua’s Immune System Research - Biofilms  51:05 Future of Accessible Research Studies 55:00 Citizen Scientists

CistaMAX | The Road To The Perfect Cistanche This month on the In Search of Insight podcast, Emiel and Erika share the inspiration behind Nootropics Depot’s new CistaMAX stack! We combined non-extracted Cistanche, a high-potency Cistanche extract, and a Supercritical Cistanche extract with Shilajit, Pregnenolone and DHEA to create CistaMAX. This combination produces a noticeable stimulating and motivating effect, and boosts the muscle-building properties of Cistanche. In this podcast, you’ll learn why we chose each ingredient in CistaMAX and what purpose it serves in the stack as a whole. You’ll also learn about the neuroscience behind the focus and mood enhancing effect of Cistanche. There’s lots of reasons why we include CistaMAX in our daily stack - it can increase feelings of hunger, which is essential when bulking and building muscle. It also gives us a noticeable energy boost that makes us want to move more. CistaMAX is a great choice for supporting fitness, motivation, and hormonal balance. Listen to our new episode to learn more! Buy CistaMAX from Nootropics Depot https://nootropicsdepot.com/cistamax-capsules/ Follow Us on Social Mediahttps://www.reddit.com/r/NootropicsDepot/https://www.instagram.com/nootropicsdepot/https://www.facebook.com/NootropicsDepot/https://www.instagram.com/insearchofinsight?igsh=MTVtdDB1d2ZpZm9sbA%3D%3D&utm_source=qr Podcast Chapters 00:00 Introduction 00:32 Exploring the elements of CistaMAX 3:46 What is the best dose for CistaMAX? 7:53 Hunger-boosting effects of CistaMAX 15:52 Steroidogenesis - androgenic benefits of CistaMAX 20:24 Gut-health benefits of Cistanche 26:51 Echinacoside and Acetoside - active compounds 32:14 Perceptible benefits of CistaMAX 32:40 CistaMAX and glucose absorption 40:22 Developing the CistaMAX stack 51:03 Pregnenolone, DHEA, and Shilajit in CistaMAX 55:29 Motivation, energy, and mood boost 1:01:51 How to determine what is and isn’t working in your stack 1:04:55 Does CistaMAX benefit workout recovery? 1:11:05 Conclusion

Tribugen | How We Took Tribulus To The Next Level This month, Emiel and Erika discuss the benefits of Tribulus Terrestris for energy, motivation, focus, and hormonal health. Making an effective stack takes more than just scientific research - this podcast episode focuses on the human element of stack creation, and why we spent so much time refining Tribugen until we got the effects profile just right. On this month’s podcast, learn more about: Tribulus Terrestris, Fenugreek, Dioscorea nipponica, and Cordyceps Monoamine oxidase A and B inhibitors Megadosing Tribugen How Nootropics Depot creates synergistic stacks Each ingredient in Tribugen was selected to compliment the stimulating and motivating effects of Tribulus, and in this episode Emiel discusses the mechanisms of action that are responsible for these effects. Before Tribugen made it’s debut, the team at Nootropics Depot tried a variety of Tribulus Terrestris extracts to find the most motivating but smooth extract that would shine as a stand-alone product. When making Tribugen, we wanted to increase the motivation benefits of Tribulus, but to smooth out the stimulation and edginess of Tribulus when taken on its own. After a year of bioassaying Tribugen, adjusting the dosages of the synergistic ingredients, and sharing the pre-released stack with friends, family and colleagues, we arrived at the finished product. If you are interested in learning more about this process, and the ingredients that make up the Tribugen stack, tune into this podcast episode! Podcast Chapters 0:00 Introduction 3:06 Mega-Dosing Tribugen 6:07 Making A Next-Level Tribulus Terrestris Extract 8:45 Why Do People Reach for Tribulus? 17:00 Where Do We Source Our Tribulus Terrestris? 18:40 β-carbolines - Monoamine Oxidase Inhibitors 21:00 Connecting Pharmacodynamics with Perceptible Benefits 24:00 Creating the Tribugen Stack 32:00 Taking Tribulus with Vignatex 34:00 How Cordyceps Interacts Within the Tribugen Stack 35:29 Cordyceps + Caffeine Connection 40:30 Choosing Synergistic Compounds + Dosages 58:30 Protodioscin + Diosgenin 1:05:19 DHEA 1:08:00 Focus Enhancing Effects of Tribugen 1:09:00 Stimulation Effects of Tribugen 1:21:00 Conclusion

March Mushroom Magic | Energy, Focus and Motivation From Your Daily Dose of Adaptogenic Mushrooms  Have you experienced the mood lifting, physically relaxing, cognition enhancing benefits of adaptogenic mushrooms? Listen to our new podcast episode as we review Nootropics Depot's new Mushroom Magic drink mixes! Emiel and Erika disucss how Nootropics Depot sources coffee, matcha and cocoa for the most delicious drinking experience, and why Mushroom Magic drinks are great to share with friends and family! Learn more about why we chose Lions Mane, Cordyceps, Tiger Milk and Poria mushroom for our blend of gut health boosting, energizing, and immune supporting drink mixes.  Are you interested in making adaptogenic mushrooms a part of your everyday supplement stack? Mushroom Magic drink mixes are the easiest and tastiest way to get full servings of four highly-effective, non-extracted mushrooms, proven for their cognition and immune health benefits. Tune into the podcast to learn more about each mushroom, and why we chose to include Lions Mane, Cordyceps, Poria and Tiger Milk in our first ever drink mix.  On this month’s podcast, learn more about: How we make mushroom magic matcha, coffee, cocoa, and lattes at home Why we chose Poria, Tiger Milk, Cordyceps and Lions Mane mushroom in our mixes How mushrooms benefit our gut health, cognition, focus, and energy Which Mushroom Magic drink mix is right for you Buy Mushroom Magic Drinks Here https://nootropicsdepot.com/mushroom-magic-coffee/ https://nootropicsdepot.com/mushroom-magic-matcha-latte/ https://nootropicsdepot.com/mushroom-magic-coffee-latte/ https://nootropicsdepot.com/mushroom-magic-matcha-powder-blend/ https://nootropicsdepot.com/mushroom-magic-cocoa/ Learn More About Lions Mane and Tiger Milk Mushrooms Follow Us on Instagram Podcast Chapters 00:00 Introduction 00:40 Introducing Mushroom Magic Drink Mixes 1:02 Gut Function and Microbiome 1:45 Beta Glucans and Polysaccharides Benefit Our Gut 3:45 Follow Us On Instagram @insearchofinsight  5:20 Poria Mushroom Sclerotium 6:25 Check Out Emiel’s Updated Stack on Reddit 8:15 Unextracted Mushrooms Contain More Beta Glucans 9:00 500 Milligrams of Poria, Lion’s Mane, Cordyceps, and 150 mg Tiger Milk 11:20 Why Mushroom Magic Drinks Contain SCOOPS 19:35 Drinking Mushroom Magic Matcha - iced latte with milk 25:20 Stevia - Why We Sourced a Higher Quality Stevia 28:00 Perceptible Effects of Mushroom Magic Matcha 31:50 Our Matcha vs. Traditional Matcha Teas 34:50 Ceremonial Grade Matcha 38:05 Effects of Poria and Tiger Milk sclerotium 49:25 Checking in On the Perceptible Benefits 56:39 The Difference Between Caffeine and Mushrooms in Isolation vs. Mushroom Magic mixes 58:05 Beta Testing Mushroom Magic drinks with friends, family and coworkers 1:07:30 Drinking Mushroom Magic Coffee 1:20:43 Non-Perceptible Benefits of Adaptogenic Mushrooms 1:26:29 Drinking Mushroom Magic Cocoa 1:39:38 Cordyceps Mushroom Health Benefits 2:08:30 Drinking Mushroom Magic Coffee Latte 2:12:40 Mushroom Magic with your Daily Supplement Stack 2:14:20 Be Moderate When Taking Multiple Doses of PreBiotics - Digestion 2:19:00 Coffee Approved By Coffee Nerds (Emiel and Erika) 2:20:30 Closing Remarks on Perceptible Benefits of Mushroom Magic DrinksLion’s Mane Mushroom | The Journey To Connect Modern Science With Traditional Chinese MedicineTiger Milk | Could It Be The New Lion's Mane? | This Rare Malaysian Mushroom Is Finally On The Prowl

Your Body’s Amazing Immune System | Is It Better To Take A Natural Approach When You Get Sick? Our immune system is our body’s defense against sickness and infection. In this month’s podcast episode, Emiel and Erika discuss inflammation, oxidation, immune supporting supplements, fermented foods, and gut health, and explore ways to stay healthy all year round. Tune into the new podcast episode to learn more about: How inflammation and oxidation are tools that the immune system uses to attack pathogens and help us recover from illness Why fermented foods and carbohydrates are essential for a healthy immune system Vitamins, minerals, and supplements that support a healthy immune system The connection between the gut and the immune system Why symptom management during illness can work against us, and what to do instead This episode is focused on why inflammation and oxidation are essential for helping us fight off pathogens, and therefore, why taking a natural approach when getting sick may help us recover faster. Sometimes, it can be advantageous to lean into the inflammation and oxidation caused by our immune system, though this can be uncomfortable. Dampening inflammation and oxidation can prolong illness, and work against our immune system’s natural response to pathogens. Follow In Search of Insight on Instagram https://www.instagram.com/insearchofinsight?igsh=ZGNjOWZkYTE3MQ%3D%3D&utm_source=qr Buy Immune Supporting Supplements from Nootropics Depot Infini C https://nootropicsdepot.com/infini-c-capsules/ Vitamin D https://nootropicsdepot.com/vitamin-d3-k2-with-vitamin-c-tablets/ https://nootropicsdepot.com/vitamin-d3-k2-c-supplement/ Vitamin B https://nootropicsdepot.com/infini-b-capsules/ Zinc https://nootropicsdepot.com/microzinc-capsules-zinc-supplement/ N-Acetyl Cysteine https://nootropicsdepot.com/n-acetyl-l-cysteine-500mg-capsules/ Micromag https://nootropicsdepot.com/micromag-capsules-optimized-magnesium/ Andrographis paniculata https://nootropicsdepot.com/andrographis-paniculata-capsules-50-andrographolides/ Reduced Glutathione https://nootropicsdepot.com/reduced-glutathione-tablets/ Recommended Podcasts on the Immune System Using Your Nervous System to Enhance Your Immune System - Huberman Labs Podcast https://www.youtube.com/watch?v=poOf8b2WE2g&t=3604s The Ultimate Cold Prevention Protocol: Strengthening The Immune System with Chris Masterjohn https://www.youtube.com/watch?v=ygeJSE2Xz4w&t=3510s Podcast Chapters 00:00 Introduction - Immune System 01:15 How Does Our Environment Affect Our Immune System? 05:30 Inflammation and Oxidation are Tools of the Immune System 06:45 Taking GABA for Immune Function 17:20 The Impact of Gut Health on the Immune System - Why Kombucha? 18:50 How Lindsay Lohan Ruined The Kombucha Industry 23:40 Stomach Acid is the First Line of Defence Against Viruses and Bacteria 26:44 How Fermentation and Food Preservation Supports Our Immune Function 30:44 Sauerkraut - Low PH Means Bad Bacteria Die, Good Bacteria Live 36:25 Short Chain Fatty Acids - Fibers, prebiotics, and biotics 42:45 How the Immune System Functions Beyond Our Gut 46:05 We Have Microbiomes Everywhere 47:55 Innate vs. Adaptive Immune System 57:30 How Genetics Factor Into Our Immune System Response 1:00:00 Leaning Into the Immune Response 1:09:43 Why Do We Get Fevers When We Get Sick? 1:30:16 Sickness Behavior 1:34:34 How To Boost Immune System When You’re Not Sick 1:54:00 Behavior, Micronutrients, and Mushrooms 2:14:00 How to Take Supplements When Getting Sick 2:18:47 Supplements to Support Your Immune System 2:33:39 GABA for the Gut, Mood, and Immune System 2:36:14 Conclusion

Video Episode | Kanna | Can This South African Succulent Make You a Better Dancer? Kanna is a unique succulent plant, originating from South Africa. It has been used as a mood and energy boosting botanical for thousands of years by the KhoiSan people of South Africa, for dancing ceremonies and as a hunting aid. In this month's podcast episode, Emiel (Nootropics Depot Product Specialist) and Erika discuss the history of Kanna, its pharmacokinetics and mechanisms of action, and how Kanna provides a distinctly uplifting effect from its serotonergic activity. Tune in to learn about dosing Kanna, taking Kanna at night clubs in Amsterdam, mesembrine, mesembrenone, and Delta 7 mesembrenone, and why you should try Kanna for its pro-social benefits. Follow In Search of Insight on Instagram https://www.instagram.com/insearchofinsight?igsh=ZGNjOWZkYTE3MQ%3D%3D&utm_source=qr Buy Full Spectrum Kanna Tablets from Nootropics Depot https://nootropicsdepot.com/full-spectrum-kanna-extract-quick-dissolve-tablets/ Read Nootropics Depot's Blog on Kanna https://nootropicsdepot.com/kanna-lift-mood-and-lower-stress Podcast Chapters 00:00 Introduction 04:10 Dosing Kanna 09:40 Stimulating Effects of Kanna 11:50 Fat or Water Soluble? Bioavailbility of Kanna 17:30 Oral & Sublingual Administration 18:53 Pharmacokinetics - T Max and C Max 34:00 Caffeine Usage and Concentration 36:00 Dynamax Pharmicokinetics 38:45 Mood, Focus, Energizing, Pro-Social Effects of Kanna 43:00 Traditional Uses of Kanna, Amanita Muscaria, Kava 50:00 Neuroscience of Kanna - Neurotransmitter Releaser 53:07 Mesembrine acts as a VMAT2 Upregulator 1:03:40 Testing Mesembrine Content of Kanna Extracts 1:14:10 Cultivars of Kanna - Sceletium tortuosum 1:14:54 What Sets Nootropics Depot’s Kanna Extract Apart 1:18:22 Beta Testing and Initial Bio-assaying 1:25:31 Kanna as a Subtle Appetite Suppresant 1:33:11 Emiel & Erika’s Current Occasional Supplements 1:47:07 Emiel & Erika’s Daily Supplement Stack 1:57:24 Conclusion

Isoliquiritigenin | Candy For Your Brain This month, learn all about neurotransmitters and the powerful mechanisms of action behind Nootropics Depot’s mood-boosting licorice root extract, Isoliquiritigenin. Erika and Emiel take you on a journey through the traditional uses of licorice, what makes it such a soothing remedy for inflammation, and where licorice candy originates from. Buy Isoliquiritigenin from Nootropics Depot https://nootropicsdepot.com/isoliquiritigenin-controlled-dissolve-tablets/ Follow In Search of Insight on Instagram https://instagram.com/insearchofinsight?igshid=MzMyNGUyNmU2YQ%3D%3D&utm_source=qr Podcast Chapters 00:00 Introduction 00:18 Licorice Root 03:53 Isoliquiritigenin 06:07 Mega-Dosing Isoliquiritigenin 10:27 Traditional Uses of Licorice Root 14:23 Why Is Licorice Candy Black? 15:28 Where The Classic Licorice Flavor Came From 24:32 Slight Detour - The Use of Quinine in Tonic Water 28:58 The Medicinal Background of Vermouth, Absinthe, Coca Cola 32:00 Tasting Dutch Licorice 35:12 Ammonium Chloride as a Cough and Mucus Remedy 43:00 Laws Against Licorice 44:54 Tasting Mild Salt Licorice 48:02 Benefits of Licorice Root and Isoliquiritigenin 54:12 The Pharmacology of Isoliquiritigenin 57:36 Neurotransmitter Basics 1:00:38 What Effects are Produced When Norepinephrine, Serotonin, and Dopamine Build Up? 1:02:34 GABA-A and GABA-B Activation 1:06:20 GABA, Amino Acid Neurotransmitter vs. Norepinephrine, Serotonin, and Dopamine Monoamine Neurotransmitter 1:08:19 Why We Typically Try to Dampen Glutamatergic Activity 1:09:40 Glycine, a Neurotransmitter 1:16:17 Dopamine D3 Agonist Effects of Isoliquiritigenin 1:18:38 Isoliquiritigenin For Pain Management 1:20:21 Isoliquiritigenin For Long Term Potentiation 1:22:47 Tonic Water - Traditional and Modern Uses 1:26:32 New Products From Nootropics Depot - Mushroom Magic Matcha 1:31:57 Why Not Ceremonial Grade Matcha? 1:36:55 The Mushroom Blend of Mushroom Magic Matcha 1:46:08 The First Scoop for Nootropics Depot 1:48:48 Full Spectrum Kanna Tablets 1:55:21 Taking Kanna at the Club 1:57:27 Conclusion

An Unexpected Journey Through The Past & Future Of Supplements With Lucas Of Boost Your Biology This month on In Search of Insight, we welcome Lucas Aoun from Boost Your Biology and embark on an unexpected, stimulating journey through the past and future of supplements. Learn More About Lucas Aoun of Boost Your Biology https://www.youtube.com/@UC4O8s5Eir3A0ULQ-0HOJr8Q https://www.youtube.com/@UCG-Da6bw7vNJ4oEkhs-D_KQ Meet Lucas and learn about his background as a biohacker, Naturopath, and supplement enthusiast. In this episode, Emiel, Lucas, and Erika share the beginnings of their journeys with supplements. They discuss what products they’ve loved and hated, new frontiers in the supplement world, and why quality and safety are the most essential elements in supplementation. Podcast Chapters 0:00 Introduction 1:15 Beta Testing Unreleased Cistanche Stack + Tribugen 5:00 Meet Lucas Aoun 6:45 Extraction Technique for Cognance - Producing a Non-Drowsy Bacopa Extract 14:00 Glycosides in Botanicals 17:21 Extraction Techniques of Cognance, Erinamax 21:47 Lucas’ Journey in Nootropics Begins 23:28 Acetyl L-Carnitine, an Early Adopted Nootropic 26:33 Emiel’s Journey in Nootropics Begins 28:41 Bioassaying Tribugen 31:59 Pre-Workout Formulations 34:15 Ginkgo Biloba 38:31 Clinical Trials vs. Empirical Evidence 39:49 Approaches to Research 42:18 Asking Questions, Asking the Right Questions 46:18 How Reddit Inspired Nootropics Depot 49:08 Benefits of Community Bioassaying 51:41 Staying Close to the Source When Researching 56:19 When Research Studies Can’t be Verified 59:02 The Origins of Acetylcholinesterase inhibitors 1:01:25 Plant Defence Systems 1:04:38 Beta Ecdysterone 1:06:39 Being Critical of Research 1:09:34 Erika’s Journey with Nootropics Begins 1:14:34 Safety Concerns of Fadogia Agrestis 1:17:21 Fadogia Agrestis Toxicology 1:20:45 The Future of Nootropic Supplements from Africa 1:21:20 Kanna and its Traditional Uses 1:38:00 Naturopathy and Nootropics 1:40:00 Criteria for Nootropics - Gurgia 1:47:40 How Traditional Chinese Medicine Informs Modern Nootropics 1:51:00 Shizandra Chinensis 1:52:20 Eria Jarensis 1:54:40 Dynamine 2:02:16 The Benefits of Progesterone 2:08:25 Enhancing Insulin Sensitivity 2:09:20 Conclusion

Megadosing And DNA Testing w/ Joe Cohen | Why The Founder Of SelfDecode Takes 150 Supplements A Day This month we welcome our featured guest, Joe Cohen of SelfDecode to the In Search of Insight Podcast. Joe’s passion for quality supplements, enthusiasm for sharing his knowledge, and commitment to lab testing is unmatched in the industry. Learn about SelfDecode, the ways that genetic testing and supplement testing work together, and how Joe Cohen tests new supplements with mega dosing. Tune into this month’s podcast episode to learn about: Why Joe Cohen takes 150+ supplements every day What sets SelfDecode apart from other supplement recommendation tools Megadosing Nootropics Depot supplements How Joe boosts his testosterone, supports thyroid function, and monitors health risks through supplementation and frequent blood tests Joe’s favorite Nootropics Depot supplements Joe's 150+ Supplement Regimen My Regimen of 150 Supplements https://selfhack.com/blog/joes-personal-health-regimen/ My Regimen of 150 Supplements (Detailed) https://selfhack.com/blog/my-regimen-of-150-supplements-why-i-take-them/ Podcast Chapters 0:00 Introduction 2:22 Why Joe Cohen Mega Doses Supplements 10:00 Megadosing Cognance 18:37 Supplements with Anti-Thyroid function 22:56 Introducing SelfDecode 31:17 Biggest Mistakes in Genetic Testing 39:52 Optimizing Your Biology 43:36 Joe Cohen’s 150+ Supplement Stack 45:49 Mood, Cardiovascular Health, Kidney Health, Thyroid Function 54:44 The Benefits of Frequent Lab Testing 58:46 Why Supplement Lab Tests and Blood Lab Tests Are Important 1:03:48 Breaking Down Joe’s Supplement Stack 1:08:14 Supplements to Support Food Tolerance 1:12:26 The Difference Between SelfDecode and Other Supplement Advice Tools 1:20:49 Checking In on the Cognance Megadose 1:21:19 How Bacosides Effect Thyroid Hormone 1:26:22 Necessity for Data in Supplementation 1:29:24 Joe’s Testosterone Benefits from Tongkat Ali 1:35:29 Clinical Trials for Supplements 1:38:20 Joe’s Favorite Nootropics Depot Supplements 1:38:20 Megadosing Sabroxy 1:50:19 The Human Element of Supplementation 1:56:45 Lab Testing and Safety of Supplements 2:02:31 Joe’s Favorite ND Supplements, Continued 2:23:51 Conclusion