Claim OwnershipThe Longevity & Lifestyle Podcast
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Claudia von Boeselager is here to empower you to live at your best and reach your highest potential by sharing groundbreaking strategies, tools, and practices for your longevity and lifestyle from the world’s pioneering experts. For more, visit: LLinsider.com Welcome to The Longevity & Lifestyle Podcast! Claudia is on a mission to help 1 billion people optimize their lives and reach their fullest potential so that they can make a positive impact in the world! Tune in to learn how to increase your healthspan, improve the quality of your life and lifestyle also around entrepreneurship, managing personal finances and investing, and much more. Topics include how to optimize your health in areas such as sleep, nutrition, cognition, metabolic health, reversing diabetes, intermittent fasting, biomarkers, gut health, hormones, the female biorhythm, skin, hair, biohacking tips, supplements, mastering your mindset, improve your relationships and overall happiness, meditation, how to perform better in business, optimize your daily routines, achieve peak performance, biohacking your age, and more. Claudia is a Peak Performance Coach and Serial Entrepreneur passionate about helping you thrive in all areas of your life & business! She knows what it’s like to feel close to burnout and not be at your best. Thanks to 10+ years of research, countless interviews with global pioneers, and hundreds of thousands spent, she continues to uncover how you, too, can achieve peak performance to live your life at its best - all while having lots of fun! So make sure to TUNE IN and start living the best version of yourself!
244 Episodes
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In this personal solo episode, Claudia shares a powerful and unexpected experience - losing her voice completely for three days.
What initially felt frustrating became a profound reminder of how the body communicates when we’re moving too fast.
In this reflective conversation, Claudia explores the deeper meaning behind forced silence and what it taught her about listening, slowing down, and reconnecting with our inner signals.
In this episode we explore:
• What losing her voice revealed about stress and overextension
• Why the body often speaks before burnout appears
• The hidden intelligence of the body and how it communicates with us
• The power of silence and stillness in a hyper-stimulated world
• How to start listening more carefully to your body’s signals
This episode is an invitation to slow down, reflect, and reconnect with the wisdom already within you.
What if your vision was telling you far more about your health than you realized?
In this fascinating episode, Dr. Meenal Agarwal, board-certified optometrist, spatial awareness expert, and authority on the eye–brain connection, reveals how vision is not just about eyesight - it’s a direct reflection of brain function, nervous system state, and emotional health.
Blending clinical science, neuroscience, mindfulness, and compassion, Dr. Agarwal explains how stress, trauma, and chronic overload subtly alter how we see the world - and how retraining vision can support healing, resilience, and longevity. From spatial awareness to visual processing, this conversation reframes vision as an active brain skill and a powerful portal into whole-body wellbeing.
We explore:
- The eye–brain connection and nervous system regulation
- How stress and trauma show up in vision
- Spatial awareness and its role in balance, safety & longevity
- Why vision is a brain function, not just an eye issue
- How mindful vision practices can support healing and clarity
This episode invites you to see differently - both literally and metaphorically.
What if desire isn’t indulgence — but your life force?
In this deeply embodied conversation, intimacy and sacred sexuality coach Olga Kaplan returns to explore how trauma lives in the body, why intimacy is about presence, and how conscious kink and BDSM can be used therapeutically for healing.
We explore:
• What intimacy truly means (deep presence with yourself and another)
• Tantra as weaving life experiences into embodied aliveness
• The difference between kink, BDSM and trauma-informed practice
• Why trauma is not the event — but what happened without consent
• How impact play, consent and role dynamics can help rewire the nervous system
• Why libido is a powerful biomarker of health and vitality
• The “sex recession” and why younger generations are disconnecting
• Practical tools: breath, sound, movement & energetic hygiene
• How long-term couples can revive polarity, play and desire
This episode is about reclaiming your body, your pleasure, your vitality - and remembering that your desire is not shameful, it’s sacred.
What if “heart health” isn’t about managing numbers… but fixing what’s driving vascular aging in the first place?
In this episode, triple board-certified cardiologist Dr. Chris Davis joins Claudia (with Lumara co-founders Ashley Madsen and Alexandra Cochrane) to unpack a modern, prevention-first approach to cardiovascular longevity.
We explore:
- Why conventional cardiology often becomes a “revolving door” of repeat events and procedures
- The “getting rusty inside” explanation of oxidative + nitrosative stress (and what it does to your arteries)
- How nitric oxide signaling influences vascular function, performance, and aging
- Why Lp(a) is trending, what matters now, and how to think about outcomes vs numbers
- Why coronary imaging (calcium and plaque assessment) can remove the guesswork
- How toxins, membranes, and mitochondria connect to cardiometabolic decline
- The emerging frontier: membrane medicine + mitochondrial support (including peptide discussion)
- Practical levers you can start with: Zone 2, environment upgrades, and reducing daily toxin load
This is a high-signal conversation for anyone who wants to measure what matters, reduce risk upstream, and build a stronger, longer healthspan.
What if psilocybin wasn’t just a mental health breakthrough — but a longevity intervention?
In this powerful, science-driven conversation, Dr. Louise Hecker shares groundbreaking research exploring how psilocybin’s active metabolite, psilocin, may influence the fundamental biology of aging.
We explore:
• How psilocybin impacts cellular senescence, one of the key drivers of aging
• The surprising effects on oxidative stress and antioxidant pathways
• What happened to telomere length in aging cell models
• Why serotonin (5-HT) receptors exist throughout the body — not just the brain
• The dramatic survival results in aged mice given monthly high-dose psilocybin
• Why psychedelic research was stalled for decades — and what’s changing now
• The potential role of psilocybin as a future geroprotective agent
This episode moves beyond hype and into mechanism — exploring how psychedelics may influence healthspan at the cellular and systemic level.
A fascinating look at how a once-misunderstood compound could reshape preventative medicine and aging science.
What if aging, fatigue, and chronic disease all shared the same root cause?
In this episode, Dr. Ash Kapoor, physician and expert in precision and longevity medicine, reveals why mitochondrial dysfunction sits at the center of metabolic breakdown, cardiovascular disease, inflammation, and accelerated aging. Rather than focusing on symptoms, Dr. Kapoor explains how cellular energy production determines how well we heal, perform, and age.
We explore why calorie counting misses the mark, how modern lifestyles damage mitochondrial function, and why restoring metabolic flexibility is one of the most powerful levers for longevity. This conversation reframes health from surface-level metrics to what’s happening deep inside the cell.
We explore:
- Why mitochondria drive energy, inflammation & aging
- The link between metabolic dysfunction and chronic disease
- How precision diagnostics reveal early dysfunction
- Why weight is a poor proxy for metabolic health
- What actually restores cellular energy & resilience
This episode offers a clear, science-based roadmap for rebuilding energy and extending healthspan—starting at the cellular level.
What if disease wasn’t inevitable — but preventable?
In this thought-provoking episode, visionary entrepreneur and philanthropist Naveen Jain challenges the foundations of modern medicine and makes the case for a bold new approach to longevity. Known for his moonshot mindset, Naveen explains why healthcare is broken, why we wait until we’re sick to act, and how proactive diagnostics and gut health could radically extend healthspan.
Drawing on his work in microbiome research, data-driven diagnostics, and preventive health, Naveen shares why curiosity, accountability, and big thinking are essential if we want to end chronic disease — not just manage it.
We explore:
- Why reactive medicine fails long-term health
- The role of gut health in disease prevention
- How diagnostics can predict illness years earlier
- Moonshot thinking applied to longevity
- What it really takes to live disease-free longer
This conversation is a wake-up call — and an invitation to rethink what’s possible for human health.
This epidsode was brought to you by:
- Kineon
Inflammation may feel like a modern problem — but Ayurveda understood it over 5,000 years ago.
In this deeply grounding episode, Dr. Shivani Gupta, Ayurvedic practitioner, researcher, and author of The Inflammation Code, reveals how ancient Ayurvedic wisdom is finally being validated by modern science. From circadian rhythm and gut health to nervous system regulation and women’s hormones, Dr. Shivani explains why so many of us are chronically inflamed — and how simple daily rituals can restore balance, energy, and longevity.
We explore why inflammation, not aging, is driving fatigue, brain fog, hormonal chaos, and perimenopause symptoms, how “mental inflammation” manifests in the body, and why turmeric and other adaptogenic herbs remain some of the most powerful anti-inflammatory tools available.
We explore:
- Why inflammation is the real root of chronic disease
- Vata, Pitta & Kapha — and how personalization really works
- Gut-brain connection through an Ayurvedic lens
- Mental inflammation, stress & nervous system overload
- How rhythm, sleep, food & ritual restore vitality
This is a powerful reminder that healing doesn’t require more force — it requires alignment.
What if stress wasn’t your enemy—but your greatest teacher?
In this episode, nervous system and HRV expert Salim Najjar reveals how heart rate variability acts as the language of the nervous system, guiding us toward emotional resilience, clarity, and longevity. Drawing from his own journey—from entrepreneurial burnout to nervous system sovereignty—Salim explains why learning to regulate stress is no longer optional in modern life.
We explore
- How childhood patterns shape adult reactions
- Why you can’t think your way out of overwhelm
- How practices like breathwork, sleep, reframing, and community can transform both health and performance.
This conversation reframes stress as a training ground—and HRV as the compass back to balance, purpose, and embodied leadership.
What if pain isn’t a sign of damage — but a signal for change?
In this powerful conversation, Dr. Kelly Starrett, world-renowned coach, physical therapist, and co-founder of The Ready State, breaks down what actually keeps the human body healthy, mobile, and resilient across a lifetime. From movement and sleep to nervous system safety and social connection, Kelly explains why most people are chasing optimization while ignoring the fundamentals that truly matter.
We explore why sitting is quietly destroying mobility, how the brain interprets pain as threat, why movement signals safety to the nervous system, and how small daily habits — like walking, sitting on the floor, breathing, and sleeping consistently — compound into extraordinary long-term health.
We explore:
- Why pain is information, not damage
- How mobility restores nervous system safety
- The overlooked role of sleep, walking & play
- Why adherence matters more than intensity
- How to build a body that supports adventure, not fear
This episode is a return to basics — and a reminder that longevity isn’t about doing more, but doing what matters, consistently.
This Episode was brought to you by:
- CAROL Bike
What if your stress responses, emotional patterns, and even motivation weren’t flaws to fix but signals to understand?
In this powerful episode, Dr. Rewire (Dr. Alok Trivedi) reveals how emotional biohacking and brain DNA insights can transform the way we relate to stress, performance, and ourselves. Drawing on nearly three decades of clinical experience, Dr. Rewire explains why emotions are data, not directives and how rewiring the nervous system can unlock peace of mind, resilience, and longevity.
We explore how personalised brain DNA patterns influence motivation, stress tolerance, recovery, and relationships and why one-size-fits-all biohacking often backfires. This conversation reframes mental health from “fixing what’s broken” to understanding how the brain is designed to protect us and how to work with it instead of against it.
We explore:
- Emotional biohacking and nervous system regulation
- Brain DNA, neurotransmitters & neuroflexibility
- Why stress, anxiety & burnout are adaptive signals
- Personalised approaches to mindset, health & longevity
- How to rewire emotions for clarity, balance & peace of mind
This is a grounded, empowering conversation that invites you to know yourself — scientifically and live in alignment with your unique design.
Tune in!
Why does hunger feel so loud — and why does willpower so often fail?
In this illuminating episode, Sarah Kennedy, founder and CEO of Calocurb, unpacks the biology of hunger, the gut-brain axis, and the powerful role of GLP-1 in appetite regulation. Drawing on over 15 years and $30 million of New Zealand government-backed science, Sarah explains why hunger is driven by our most primitive brain systems — and how understanding this biology can finally bring peace with food.
We explore how bitter taste receptors in the gut stimulate appetite-suppressing hormones, why dieting can actually increase hunger over time, and how natural GLP-1 activation differs fundamentally from pharmaceutical injections like Ozempic.
We explore:
- The evolutionary biology of hunger and food noise
- How GLP-1, CCK and PYY regulate appetite
- Why calorie restriction backfires long-term
- Natural vs synthetic GLP-1 pathways
- How appetite regulation supports metabolic health, insulin sensitivity & longevity
This is a science-grounded, compassionate conversation that reframes hunger — not as a personal failure, but as biology you can finally work with.
This episode was brought to you by:
- Calocurb
What happens when life gives you a second chance?
In this powerful episode, world-record mountaineer, author, and resilience expert Jenn Drummond shares how surviving a near-fatal car crash became the defining line between the life she was living — and the life she chose to claim.
From promising she’d “do something significant” if she lived, to summiting Everest and completing the second-highest peaks on every continent, Jenn reveals why courage isn’t something you’re born with — it’s something you build, one brave step at a time.
We explore:
- How trauma can become a catalyst for purpose
- Why courage is trained, not innate
- The mindset that turns fear into forward motion
- What it means to shift from success to significance
- How to model resilience for your children — and yourself
This is a deeply human conversation about choosing life, rewriting identity, and climbing the inner mountains that matter most.
This episode was brought to you by:
- Carolbike
- Kineon
- Calocurb
What if your cravings, emotional eating, and daily food choices weren’t driven by lack of willpower — but by biology, psychology, and an environment designed to hijack your instincts?
In this eye-opening episode, visionary entrepreneur and creator of WildFit, Eric Edmeades, breaks down the evolutionary roots of hunger, the truth about sugar and stress, and why most modern diets fail. Eric reveals how our ancient programming collides with today’s food landscape — and how to reclaim our natural vitality by understanding what the body is truly asking for.
With warmth, clarity, and powerful storytelling, Eric guides us through the deeper emotional patterns behind eating, the role of seasonal nutrition, and how to finally achieve food freedom without discipline, restriction, or shame.
We explore:
- The evolutionary roots of hunger, cravings & emotional eating
- Why diets fail — and how to reset your body’s real nutritional needs
- The WildFit method for sustainable health & metabolic healing
- Sugar, stress & the biology of modern overeating
- How to eat in alignment with your natural rhythms and instincts
This conversation will transform the way you think about food — and the way you nourish your life.
Tune in and learn how to return to your most vibrant, instinctive, healthy self.
What if health optimization wasn’t just for the elite — but something every teacher, firefighter, and family could access?
In this inspiring episode, Jim Donnelly, founder and CEO of Humanaut Health (and former founder of Restore Hyper Wellness), shares how he’s building the most comprehensive, prevention-driven longevity model to date. From advanced diagnostics and regenerative medicine to behavior change and coaching, Jim reveals what it truly takes to add 10–20 healthy, vibrant years to life.
He opens up about the loss of his father, surviving a near-fatal car accident, and how stem cell therapy transformed his recovery — all of which shaped his mission to scale health optimization with integrity, accessibility, and world-class medical excellence.
We explore:
- Why foundational habits (sleep, movement, nutrition, stress) drive 90% of results
- How Humanaut uses 150+ diagnostics to find root causes
- Why regenerative medicine works best on a healthy foundation
- How to democratize longevity without sacrificing quality
- What it takes to reverse metabolic dysfunction — 86% success in under 6 months
This conversation is a powerful reminder that the future of medicine is preventive, personalized, and incredibly hopeful.
Tune in and discover what’s possible when we invest in health — not after we’re sick, but while we’re thriving.
Pain might feel like an inevitable part of aging but what if it’s actually fixable?
In this episode, Forrest Smith, CEO and co-founder of Kineon, unpacks the cutting-edge science behind red light and laser therapy, why inflammation is the real driver of pain and accelerated aging, and how daily, targeted phototherapy can transform mobility, energy, and long-term health.
We explore the link between inflammation and chronic disease, the surprising gut–brain–thyroid connection, and why repairing internal tissue with the right light wavelengths can dramatically shift your health trajectory.
We cover:
- The four pillars of red light therapy at the cellular level
- Why treating inflammation is key to longevity and mobility
- How gut health, thyroid function & brain health connect through light
- Red light protocols for pain relief, energy, mood & recovery
- How Kineon’s Move+ Pro is disrupting traditional pain management
If you want to stay active, mobile, and pain-free for life, this conversation is a must-listen.
Tune in and learn how to use light to heal your body from the inside out.
When it comes to longevity, your gut might hold the master key. In this fascinating episode, Colleen Cutcliffe, PhD, CEO and co-founder of Pendulum Therapeutics, reveals how a single gut bacterium—Akkermansia muciniphila—is transforming the future of metabolic and hormonal health.
From her daughter’s early health challenges to pioneering live Akkermansia in supplement form, Colleen shares her journey from biotech to natural therapeutics. Discover how the microbiome impacts metabolism, energy, brain function, menopause, and even GLP-1 hormone production—the same pathway drugs like Ozempic mimic.
We explore:
- Why 88% of Americans are metabolically unhealthy
- The gut’s role as the root system of longevity
- How Akkermansia acts as “the glue” for gut lining integrity
- The connection between gut bacteria and women’s hormones
- Breakthroughs in microbiome-based therapies and “bugs as drugs”
Whether you’re curious about reversing metabolic dysfunction or optimizing your healthspan naturally, this episode is your deep dive into the science and soul of gut health.
Sponsors:
- Carol Bike: Get $300 off from Oct 17 – Dec 26, 2025, with code CLAUDIA, and enjoy an ongoing $100 off afterward. Visit carolbike.com/claudia and use code CLAUDIA at checkout.
- Pendulum: Get 20% off your first membership order at pendulumlife.com/CLAUDIA20, your discount applies automatically.
- Juvent: Get $300 off the Juvent Micro-Impact Platform at juvent.com/CLAUDIA and check out with code CLAUDIA.
- Kineon: Get 10% off your MOVE+ Pro at kineon.io/claudia
- Calocurb: Get 10% off at calocurb.com/longevityandlifestyle with code CLAUDIA10 at checkout.
When it comes to longevity, your gut might hold the master key. In this fascinating episode, Colleen Cutcliffe, PhD, CEO and co-founder of Pendulum Therapeutics, reveals how a single gut bacteriu, Akkermansia muciniphila - is transforming the future of metabolic and hormonal health.
From her daughter’s early health challenges to pioneering live Akkermansia in supplement form, Colleen shares her journey from biotech to natural therapeutics. Discover how the microbiome impacts metabolism, energy, brain function, menopause, and even GLP-1 hormone production—the same pathway drugs like Ozempic mimic.
We explore:
- Why 88% of Americans are metabolically unhealthy
- The gut’s role as the root system of longevity
- How Akkermansia acts as “the glue” for gut lining integrity
- The connection between gut bacteria and women’s hormones
- Breakthroughs in microbiome-based therapies and “bugs as drugs”
Whether you’re curious about reversing metabolic dysfunction or optimizing your healthspan naturally, this episode is your deep dive into the science and soul of gut health.
This episode is brought to you by Pendulum - get 20% off your first membership order at pendulumlife.com/CLAUDIA20, your discount applies automatically.
What’s the true return on investment when it comes to your health?
In this special episode, Claudia joins Liz Bradford on the Health ROI Show to share how she reversed her biological age by 17 years, all while running multiple businesses and raising a family. Together, they unpack the data-driven strategies that deliver the biggest health ROI: from optimizing sleep and managing stress to rebalancing hormones and designing sustainable daily systems that work for high performers.
You’ll learn:
- Why your “why” is the foundation of lasting transformation
- The non-negotiables that drive real energy and focus
- How to use data to personalize your health optimization
- Simple, high-impact longevity habits anyone can start today
If you’ve ever felt too busy to prioritize your health, this episode will shift your mindset — and your biology. Tune in to discover how to maximize your energy, longevity, and vitality, one smart investment at a time.
Sponsors:
Carol Bike: Get $300 off from Oct 17 – Dec 26, 2025, with code CLAUDIA, and enjoy an ongoing $100 off afterward. Visit carolbike.com/claudia and use code CLAUDIA at checkout.
Pendulum: Get 20% off your first membership order at pendulumlife.com/CLAUDIA20, your discount applies automatically.
Juvent: Get $300 off the Juvent Micro-Impact Platform at juvent.com/CLAUDIA and check out with code CLAUDIA.
Kineon: Get 10% off your MOVE+ Pro at kineon.io/claudia
Calocurb: Get 10% off at calocurb.com/longevityandlifestyle with code CLAUDIA10 at checkout.
What if the secret to longevity wasn’t more movement but the right kind of movement?
In this episode, Peter Simonson, President, Co-Founder, and Board Member of Juvent, reveals how NASA-backed micro-impact technology is transforming bone density, balance, and vitality from the ground up.
We unpack the science of mechanotherapy, how gentle vibrations can stimulate bones and circulation, and why this “passive exercise” could be a game-changer for aging well — especially for those recovering from injury or struggling with mobility.
We explore:
- The link between bone health and longevity
- How NASA research inspired Juvent’s micro-impact platform
- The surprising benefits for balance, circulation, and energy
- Why strong bones equal longer, healthier lives
Sponsors:
This episode is brought to you by Juvent, creators of the Micro-Impact Platform. A breakthrough technology that helps improve circulation, bone health, and reduce pain naturally. Just stand on it for 20 minutes a day and let gentle micro-impacts work at the cellular level to support healing and mobility. Get $300 off the Juvent Micro-Impact Platform at juvent.com/CLAUDIA with code CLAUDIA
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