Believe in Progress: an AACR Foundation Podcast

What does it take to revive a beloved Philadelphia tradition after a decade-long hiatus? In this episode of Believe in Progress, a podcast of the AACR Foundation, we sit down with two men who are bringing professional cycling back to the streets of Philadelphia. Part One introduces the grassroots origins of the revival. We meet Carlos Rogers, a local hairstylist and cycling enthusiast who spent three years pitching a vision to bring the race back, and Eric M. Robbins, the business leader who joined forces to turn that vision into reality—the Philadelphia Cycling Classic. They discuss the pivotal moment former Philadelphia Mayor Michael Nutter joined the team and the emotional weight of earning community trust. Part Two dives into the details of the race itself, scheduled for August 30, 2026. Carlos and Eric walk us through the iconic 14-mile circuit, including the grueling "Manayunk Wall" with its steep grade. They discuss the projected economic impact of more than 100,000 spectators and the race’s identity as "The People’s Race." And then the conversation turns to the heart of the mission: the collaboration with the American Association for Cancer Research (AACR) as the charity partner for the race to raise critical funds for lifesaving cancer science and medicine. The AACR Riders for Research participants will cycle the 14-mile course before the professional race begins. Eric also shares the personal story of losing his mother to ovarian cancer in 2004, highlighting how resilience is the driving force behind this Philadelphia comeback story. Featured Guests: Carlos Rogers - Co-Founder, Philadelphia Cycling Classic A Philadelphia native, professional hairstylist, and lifelong cyclist, Carlos is the visionary "spark" behind the initiative. His three-year grassroots campaign and refusal to let the tradition die led to the revival of one of the city's cherished sporting events. Eric M. Robbins - Co-Founder, Philadelphia Cycling Classic Bringing decades of financial and operational leadership, Eric is the strategist ensuring the race's success. Deeply connected to the Philadelphia community, he is driven by a desire to give back to the city and a personal commitment to cancer awareness following the loss of his mother. Key Topics: · The Origin Story: How a hairstylist’s passion project evolved into a major international sporting event · Building the Team: The critical involvement of former Mayor Michael Nutter and the emotional moment he told Carlos, "I believe in you" · The Course: A breakdown of the 14-mile loop, including the Ben Franklin Parkway, Kelly Drive, and the infamous Manayunk Wall · Economic and Community Impact: Projecting more than 100,000 spectators and millions of dollars in economic impact for Philadelphia · Strategic Partnerships: The role of the AACR as the event’s official charity partner · Resilience and Loss: Eric’s personal reflection on his mother’s battle with ovarian cancer and how it shapes his work ethic · The 2026 Vision: Why the race was moved to August 30 and the plans for a multi-day fan festival Take Action to Propel Progress in Cancer Research: If this episode moved you, here’s how you can take action to advance cancer research: · Donate to the AACR: Fuel lifesaving cancer research at https://AACR.org/Give · Share This Episode: Help amplify the message that bold ideas and global collaboration can change the future of cancer care · Team Up with AACR Riders for Research at the 2026 Philadelphia Cycling Classic – AACR Charity Ride: https://AACR.org/PCC · Subscribe to Believe in Progress: Listen on Apple Podcasts, Spotify, YouTube, or wherever you get your podcasts · Learn More About the Philadelphia Cycling Classic at https://www.philadelphiacyclingclassic.com/ Production Credits: Host: Mitch Stoller Guests: Eric M. Robbins; Carlos Rogers Executive Producer: Anthony Lopes Executive Producer: Michael Leary Director: Anthony Lopes Creative Director / Director of Photography: Michael Leary Writer: Anthony Lopes Editor: Michael Leary Associate Producer: Heather Holland Check out more episodes: https://AACR.org/BelieveInProgress Believe in Progress is produced by CollegeCast LLC.

What happens when a healthy 8-year-old boy begins tripping, falling, and experiencing double vision? For Katie and Nick Macri, and grandparents Tim and Maggie McNiff, these early warning signs led to every family’s worst nightmare: a diagnosis of diffuse intrinsic pontine glioma (DIPG), a rare and aggressive tumor located in the brainstem. In this emotional episode of Believe in Progress, brought to you by the AACR Foundation, we sit down with the family of John Paul (JP) to discuss their journey through diagnosis and treatment. Part One introduces us to JP and his family. Katie and Nick recount the heartbreaking timeline from subtle symptoms to the harrowing moments of receiving the diagnosis. They discuss the devastating nature of a tumor located in the pons region of the brainstem and the "state of unknowing" that follows such news. We also hear from JP’s grandparents, Tim and Maggie, on dropping everything to support their grandchildren, and how the family navigated difficult conversations with JP’s older brother, Luke. Part Two focuses on the incredible resilience that defines JP’s journey. The family discusses their decision to pursue a clinical trial involving CAR T-cell therapy at Seattle Children’s Hospital to preserve JP's quality of life. The conversation shifts to the power of community—from a neighborhood Nerf war to the James Madison University football team adopting JP as an honorary captain. Finally, Nick and Tim discuss their initiative to accelerate research through the "M3 database," an AI-driven project designed to speed up data sharing for pediatric brain cancer. This is a story about cancer science and a little boy who refuses to let a dire diagnosis define his spirit. Featured Guests Katie and Nick Macri – John Paul’s parents Katie and Nick share their raw and honest experience navigating pediatric cancer, balancing full-time work with cross-country travel for treatment, and relying on their deep faith to carry the burden of the unknown. Tim and Maggie McNiff – John Paul’s grandparents Tim and Maggie offer the perspective of the extended family "village." They discuss the role of grandparents in a crisis and their work to support logistical and scientific initiatives to help their grandson. Key Topics: Part One – The Diagnosis and The Family Unit • Early Warning Signs: Identifying subtle symptoms like redness in eyes, head tilting, and loss of balance • The Diagnosis: Understanding DIPG and the initial prognosis • Sibling Impact: How JP’s older brother Luke is processing the illness and the attention surrounding it • The Power of Vulnerability: Why Nick and Katie chose to be open on CaringBridge rather than keeping the diagnosis private Part Two – Innovation, Community and The "Green Bracelet" Army • CAR T-Cell Therapy: Choosing an innovative clinical trial over traditional chemotherapy to maintain quality of life • The JMU Connection: How the James Madison University football team embraced JP, from the weight room to the coin toss • The M3 Database: Nick and Tim’s effort to use AI and data centralization to help researchers share MRI and genomic data faster • Community Support: How neighbors, colleagues, and strangers lift the family up daily Take Action to Advance Cancer Science and Medicine: If this episode moved you, here’s how you can take action to support families like the Macris: • Donate to the AACR: Fuel lifesaving innovation at https://AACR.org/Give • Check out the inaugural AACR Pediatric Cancer Progress Report, which highlights the advances and challenges in the field, at https://PediatricCancerProgressReport.org • Support additional organizations that advocate for pediatric cancer research, including Tough2gether Foundation • Follow along with JP’s story at CaringBridge • Share this Episode: Help amplify the message that bold ideas and global collaboration can change the future of cancer care • Subscribe to Believe in Progress: Listen on Apple Podcasts, Spotify, YouTube, or wherever you get your podcasts Production Credits: Host: Mitch Stoller Guests: Katie Macri, Nick Macri, Tim McNiff, and Maggie McNiff Executive Producer: Anthony Lopes Executive Producer: Michael Leary Director: Anthony Lopes Creative Director / Director of Photography: Michael Leary Writer: Anthony Lopes Editor: Michael Leary Associate Producer: Heather Holland Check out more episodes: https://AACR.org/BelieveInProgress Believe in Progress is produced by CollegeCast LLC.

What happens when an elite athlete, known for his focus and discipline, faces a life-changing diagnosis? In this episode of Believe in Progress, a podcast of the AACR Foundation, we sit down with Steve Dawson, a titan in the world of pickleball, to discuss his experiences with prostate cancer. Part One: We explore Steve’s initial diagnosis, which came as a shock following a routine physical with no prior symptoms. Steve discusses his decision-making process regarding surgery versus radiation and the "state of unknowing" that accompanies a cancer journey. He discusses how his athletic background prepared him to tackle treatment head-on and the importance of men overcoming the stigma of discussing their health. Part Two: We dive into the intersection of passion and recovery. Steve shares how a cancer recurrence became the catalyst for launching his own paddle company, Aura, and reflects on the unique, supportive nature of the pickleball community. He shares candid, humorous, and vulnerable stories, including winning a bronze medal at the US Open while recovering from surgery, and discusses his "expiration date" philosophy that makes every sunset better and every glass of wine taste a little sweeter. This conversation highlights the importance of early detection, the power of an active lifestyle, and the refusal to let a diagnosis define one’s limits. Featured Guest Steve Dawson - Professional Pickleball Player, Coach, and Entrepreneur A legend in the sport with 18 majors to his name, Steve Dawson is the owner of the Bobby Riggs Racket and Paddle Club and the founder of Aura. He uses his platform to advocate for prostate cancer awareness and emphasizes the critical need for PSA screenings. Key Topics: Part One – The Diagnosis & Mindset - The silent nature of prostate cancer: How a routine physical that found a spike in PSA levels led to Steve’s diagnosis. - Navigating treatment options: The choice between surgery and radiation. - The "state of unknowing": Managing the anxiety of diagnosis and recurrence. - Breaking the silence: Why Steve feels men should talk more openly about cancer and "Man Up to Cancer." - How physical fitness and an athlete’s mentality aided Steve’s recovery from surgery. Part Two – Community, Innovation & Resilience - The pickleball melting pot: How the sport builds a diverse, supportive network for patients. - Turning adversity into action: How a cancer recurrence motivated the founding of his company, Aura. - The bronze medal story: A humorous and gritty look at competing in the US Open immediately post-surgery. - Integrative approaches: Combining Western medicine with Eastern holistic practices (diet, herbs, and stretching). - Reframing the narrative: Viewing cancer survivorship as a tool to appreciate the vibrancy of life. Take Action in the Fight Against Cancer: If this episode moved you, here’s how you can take action to advance cancer research: - Get screened: If you are eligible, talk to your doctor about a PSA test. It could save your life. - Donate to the AACR: Fuel lifesaving innovation at https://AACR.org/Give - Share this episode: Help amplify the message that early detection and community support can change outcomes. - Subscribe to Believe in Progress: Listen on Apple Podcasts, Spotify, YouTube, or wherever you get your podcasts. Production Credits: Host: Mitch Stoller Guest: Steve Dawson Executive Producer: Anthony Lopes Executive Producer: Michael Leary Director: Anthony Lopes Creative Director / Director of Photography: Michael Leary Writer: Anthony Lopes Editor: Michael Leary Associate Producer: Heather Holland Believe in Progress is produced by CollegeCast LLC. Check out more episodes: https://AACR.org/BelieveInProgress

What happens when a life in media, advocacy, and leadership converges on a mission to transform the way we support people with cancer? On this episode of Believe in Progress, the AACR Foundation’s podcast, we hear from Suzanne Stone, an Emmy-winning storyteller, nonprofit champion, and the President and CEO of Livestrong. From television studios to basketball courts to cancer care nonprofits, Suzanne’s career has always centered on lifting others up. In a special full-circle moment, host Mitch Stoller, who served as Livestrong’s President and CEO from 2003 to 2007, talks with Suzanne to discuss the organization's legacy and its future. Suzanne shares the career path that brought her to Livestrong, including how coaching women’s basketball taught her vital lessons about empathy and listening that now inform her leadership style. She explores the organization's evolution, from the decision to bring back the iconic yellow and black branding to the launch of Ellis, a groundbreaking AI companion designed to help cancer survivors navigate their journey. This conversation dives deep into the philosophy of "saving all the starfish," moving beyond individual aid to creating systemic impact at scale. Suzanne outlines how Livestrong is building self-sustaining micro-businesses to ensure that no one faces cancer alone, today or years from now. Featured Guest Suzanne Stone - President and CEO, Livestrong: Leading one of the most recognized names in cancer advocacy, Suzanne is focused on patient-centered solutions, equity, and enduring hope. She discusses how her background in media and coaching prepared her to lead Livestrong into its next chapter, emphasizing the power of community, physical movement, and innovative technology in cancer recovery. Key Topics: • A Legacy of Bravery: How Livestrong has evolved over 28 years while maintaining its core mission to ensure no one faces cancer alone. • From Storytelling to Service: Suzanne’s non-linear career path from TV production to coaching basketball and leading nonprofits like Court Appointed Special Advocates (CASA) and Susan G. Komen. • Impact at Scale: Reinterpreting the "Starfish Parable" to focus on solving root causes rather than just individual cases. • Innovation in Care: The development of Ellis, an AI-powered guidebook that acts as a closed-loop conversation partner for survivors seeking resources. • The Power of Yellow: The strategic decision to bring back the iconic yellow and black brand identity as a symbol of hope and resilience. • Exercise Oncology: The evolution of Livestrong at the Y into Cancer Fit, an accessible, on-demand digital training platform for survivors and trainers. • Leadership Lessons: How coaching a community college basketball team taught Suzanne the difference between hearing and truly listening with empathy. • Future Sustainability: Building self-sustaining micro-businesses to fuel Livestrong’s mission independent of external economic factors. Take Action in the Fight Against Cancer: If this episode moved you, here’s how you can take action to advance cancer research: • Donate to the AACR: Fuel lifesaving cancer research at https://AACR.org/Give • Support Survivorship: Learn more about Livestrong’s resources at https://Livestrong.org • Share this episode: Help amplify the message that bold ideas and global collaboration can change the future of cancer care • Subscribe to Believe in Progress: Listen on Apple Podcasts, Spotify, YouTube, or wherever you get your podcasts Production Credits: Host: Mitch Stoller Guest: Suzanne Stone Executive Producer: Anthony Lopes Executive Producer: Michael Leary Director: Anthony Lopes Creative Director / Director of Photography: Michael Leary Writer: Anthony Lopes Editor: Michael Leary Associate Producer: Heather Holland Believe in Progress is produced by CollegeCast LLC. Check out more episodes: https://AACR.org/BelieveInProgress

What does it take to lead one of the world’s largest gatherings of cancer researchers and to deliver cancer care on the front lines of a war zone? In this powerful episode of Believe in Progress, brought to you by the AACR Foundation, we sit down with two extraordinary individuals shaping efforts to drive progress in cancer science and medicine. Part One features Dr. Matthew G. Vander Heiden, Cochair of the AACR Annual Meeting, Director of the Koch Institute for Integrative Cancer Research at MIT, and practicing oncologist at Dana-Farber Cancer Institute. Dr. Vander Heiden offers a behind-the-scenes look at what goes into building a scientific meeting of this scale, why interdisciplinarity matters, and how today’s trainees will become tomorrow’s leaders. He also reflects on his work in cancer metabolism and how caring for patients shapes his scientific mission. Part Two features Dr. Inesa Huivaniuk, surgical oncologist at the Kyiv Regional Oncological Center and Executive Director of the Global Medical Knowledge Alliance (GMKA) in Ukraine. Dr. Huivaniuk shares what it’s like to perform surgery during missile attacks, support displaced patients, and maintain cancer care amid war. Her work highlights resilience, innovation, and the global collaboration required to ensure every patient receives care, even in wartime crisis. Together, these conversations capture the spirit of the AACR Annual Meeting: uniting every discipline, every discovery, and every person behind progress against cancer. This special episode of Believe in Progress was recorded live at the AACR Annual Meeting in Chicago. It’s part of a series that features dynamic conversations with researchers, clinicians, entrepreneurs, and student scholars contributing to the effort to defeat cancer. From breakthrough diagnostics to trailblazing health services research, our guests in this series share their stories of science, innovation, and hope. Featured Guests Dr. Matthew G. Vander Heiden - Cochair, AACR Annual Meeting; Director, Koch Institute for Integrative Cancer Research at MIT A global leader in cancer metabolism and scientific strategy, Dr. Vander Heiden discusses how the Annual Meeting is built, why collaboration across disciplines matters, and how supporting future scientists remains central to the AACR’s mission. Dr. Inesa Huivaniuk - Surgical Oncologist, Kyiv Regional Oncological Center; Executive Director, GMKA Ukraine From operating during missile strikes to restoring cancer services in a war zone, Dr. Huivaniuk speaks to the courage and innovation required to care for patients under extraordinary circumstances. Key Topics: Part One – Dr. Vander Heiden - How the AACR Annual Meeting, with its more than 22,000 attendees, is planned - How the conference ensures representation across basic science, clinical trials, population science, and policy - How it spotlights emerging researchers and first-time presenters - Insights into cancer metabolism and nutrient pathways in tumor growth - Balancing leadership, research, and clinical practice - How the AACR supported his early career and why he’s committed to mentoring the next generation Part Two – Dr. Huivaniuk - Delivering cancer care in a war zone: disruption, courage, and adaptation - Providing care to both cancer patients and injured soldiers - Barriers to medication access, radiation supplies, and medical infrastructure - Supporting physicians who cannot travel to meetings for education and collaboration opportunities - Using technology and international partnerships to maintain continuity of care - Personal experiences operating under missile fire and her refusal to abandon patients - How her mother’s medical journey inspired her to pursue medicine Take Action in the Fight Against Cancer: If this episode moved you, here’s how you can take action to advance cancer research: - Donate to the AACR: Fuel lifesaving innovation at https://AACR.org/Give - Share this episode: Help amplify the message that bold ideas and global collaboration can change the future of cancer care - Subscribe to Believe in Progress: Listen on Apple Podcasts, Spotify, YouTube, or wherever you get your podcasts Production Credits: Host: Mitch Stoller Guests: Matthew G. Vander Heiden, MD, PhD; Inesa Huivaniuk, MD, MPA Executive Producer: Anthony Lopes Executive Producer: Michael Leary Director: Anthony Lopes Creative Director / Director of Photography: Michael Leary Writer: Anthony Lopes Editor: Michael Leary Associate Producer: Heather Holland Believe in Progress is produced by CollegeCast LLC.

What does it take to face cancer head-on, twice, and still find the strength to run toward progress? In this powerful episode of Believe in Progress, brought to you by the AACR Foundation, Rhett Austell shares his deeply personal journey through stage 4 appendix cancer, fatherhood, advocacy, and the fight for his life. Rhett’s story is one of resilience. From the sudden onset of cancer in his late 30s to undergoing major surgery, chemotherapy, and still lacing up to run the Broad Street Run in Philadelphia, he embodies what it means to keep going, no matter the odds. His passion for funding cancer research is fueled by both the personal loss of his father and by hope: through his father-in-law’s survival, thanks to a clinical trial. This special extended episode includes a heartfelt epilogue recorded after Rhett’s recent cancer recurrence, where he speaks openly about the realities of a second diagnosis, his continued treatment, and what drives him to keep fighting—not just for himself, his wife, and his four daughters, but for all cancer patients and their families. Key Topics: - The shocking discovery of stage 4 appendix cancer at age 38 - The emotional rollercoaster of becoming a father again amid diagnosis - Lessons learned from his father’s and father-in-law’s cancer journeys - Running the Broad Street Run after major surgery and raising more than $9,000 - Facing a cancer recurrence and embracing advocacy with renewed urgency - The importance of time, clinical trials, and fully funding cancer research - What it means to believe in progress, even in the face of setbacks Episode Chapter Markers (Timestamps): 00:00 – Introduction to Believe in Progress 00:53 – Rhett's Story Begins 03:09 – A Surprise Diagnosis and a New Baby on the Way 08:12 – Treatment, Surgery, and Finding Strength Through Family 09:28 – Cancer in the Family: Stories of Loss and Survival 14:48 – Why Cancer Research Matters Now More Than Ever 16:55 – Running Again: From the Hospital to the Finish Line 20:23 – Fundraising, Broad Street Run, and Victory 21:49 – Epilogue: Facing Recurrence with Purpose 27:34 – Rhett’s Second Round of Treatment 32:29 – Continued Advocacy in the Face of Uncertainty 36:04 – Looking Ahead: Hope, Family, and Next Goals If this episode moves you, here’s how you can take action to advance cancer research: - Donate to the AACR: Fuel lifesaving innovation at https://AACR.org/Give - Share this episode: Send it to inspire others in your network - Subscribe to Believe in Progress: Listen on Apple Podcasts, Spotify, YouTube, or wherever you get your podcasts Production Credits: Host: Mitch Stoller Guest: Rhett Austell Executive Producer: Anthony Lopes Executive Producer: Michael Leary Director: Anthony Lopes Creative Director / Director of Photography: Michael Leary Writer: Anthony Lopes Editor: Michael Leary Associate Producer: Heather Holland Believe in Progress is produced by CollegeCast LLC.

Your support matters. Help accelerate progress against cancer: - Donate to the AACR: Fuel lifesaving cancer research at https://AACR.org/Give. - Share this episode: Amplify Patty’s and Vicki’s messages of early detection, advocacy, and hope. - Subscribe to Believe in Progress: Follow us on Apple Podcasts, Spotify, YouTube, or wherever you listen. What does it look like to face breast cancer with courage, clarity, and community? In this episode, we talk with Patty Guthrie and Vicki Courlang about the moments that changed everything in their lives and the choices that carried them forward. Patty describes retiring after 25 years of teaching, staying on top of her annual mammograms, and catching her cancer early—at Stage 1 in 2020—as well as navigating treatment during COVID-19. She credits her care team at Memorial Sloan Kettering, daily gratitude, and walking five to six days per week as pillars of her recovery. Vicki brings a clinician’s insight to a patient’s journey. A former oncology nurse, she recognized something was “off” long before her diagnosis with Paget’s disease of the breast. Paget’s is a rare condition that, for Vicki, didn’t appear on standard mammograms. She emphasizes listening to your body, seeking prompt evaluation for changes, and advocating for screening access at younger ages. Both guests underscore the lifesaving importance of early detection, the reality of vulnerable moments, and the power of family, friends, and compassionate care. Their message is clear: education, advocacy, and cancer research save lives, and hope grows from science and facing our challenges of cancer together. Episode Highlights: - Early Detection Saves Lives: Patty’s annual screening caught a small, hard-to-feel tumor, and Vicki’s Paget's symptoms appeared externally and did not show on standard mammograms. This is where self-awareness and follow-up mattered. - Treatment in a Pandemic: Chemotherapy and radiation during COVID-19 meant isolation at appointments. However, nurses, techs, and loved ones created a safety net. - Caregiver and Patient Dual Lens: Vicki’s oncology background helped her understand next steps; Patty learned fast and stayed positive through her cancer journey. - Support Systems: Spouses, children, and close friends (shoutouts included) made a big difference. They helped with rides to appointments, meals, calls, and presence. - Survivorship Milestones: From frequent follow-ups to annual imaging and bone-density checks, survivorship is a structured path, which includes daily movement and gratitude. - Mindset Shifts: Cancer doesn’t define who you are; it’s part of what you are. Boundaries, positivity, and purpose take center stage. - Practical Advice: Stay informed. Get your screenings. Seek second opinions. Choose a team and a care plan you feel confident in and move forward. How You Can Help - Donate to the AACR: Support world-class cancer research at AACR.org/Give - Subscribe & Share: Help this episode reach patients, caregivers, and clinicians who need it - Leave a Review: Ratings and reviews help others discover the show Production Credits: Host: Mitch Stoller Guests: Patty Guthrie and Vicki Courlang Executive Producer: Anthony Lopes Executive Producer: Michael Leary Director: Anthony Lopes Creative Director / Director of Photography: Michael Leary Writer: Anthony Lopes Editor: Michael Leary Associate Producer: Heather Holland Believe in Progress is produced by CollegeCast LLC.

Your support matters! Take action to propel progress in cancer science and medicine: - Donate to the AACR: Fuel lifesaving innovation by supporting cutting-edge cancer research at https://AACR.org/Give - Share this episode: Help amplify Justin’s story and advance research for the benefit of caregivers, survivors, and all those impacted by cancer - Subscribe to Believe in Progress: Find us on Apple Podcasts, Spotify, YouTube, or wherever you listen Episode Summary: How far would you go to protect the person you love most in the world? In this emotional and inspiring episode, Justin Wineburgh, President and CEO of Alkemy X, sits down with host Mitch Stoller to share the extraordinary story of his mother Iris: a single mom of three, a “force of nature,” and a woman whose love defined his world. Justin reflects on the moment everything changed: Iris’s ovarian cancer diagnosis on December 30, 1999. From that day forward, he became not just her son, but her advocate, her caregiver, and her anchor. Together, they navigated hospital rooms, treatment plans, and the emotional landmines of uncertainty, while holding tightly to moments of laughter, love, and connection. Faced with heartbreak after hearing about his mother's diagnosis, Justin found purpose: immersing himself in cancer research, standing fiercely by his mother’s side, and eventually becoming a father himself just weeks after her death in 2024. Today, he carries her legacy forward through storytelling, empathy, and relentless hope. Episode Highlights: - Meeting Iris: A single mom of three boys and a fierce, vibrant woman remembered as “a force of nature” - The Diagnosis: How a flip phone call from a young resident changed their lives forever - The Cancer Journey: Chemotherapy, second opinions, and choosing to get care close to home in Philadelphia - Caregiver Realities: Rage, love, exhaustion, and learning that “no one knows nothing” - Life After Loss: Navigating grief, becoming a father, and wearing Iris’s belt as a daily reminder of love - Why Research Matters: The drug that helped in her final year didn’t exist when she was first diagnosed - A Son’s Message: “If you can get one extra day with your loved one because of research, it’s worth everything” Production Credits: Host: Mitch Stoller Guest: Justin Wineburgh Executive Producer: Anthony Lopes Executive Producer: Michael Leary Director: Anthony Lopes Creative Director / Director of Photography: Michael Leary Writer: Anthony Lopes Editor: Michael Leary Associate Producer: Heather Holland Believe in Progress is produced by CollegeCast LLC

Your support matters. Help us take action in the fight against cancer: - Donate to the AACR: Fuel innovation by supporting cutting-edge cancer research at https://AACR.org/Give - Share this episode: Help amplify Larry’s story and inspire action to advance cancer research - Listen and subscribe: Find Believe in Progress on Apple Podcasts, YouTube, Spotify, or wherever you get your podcasts How can strategic thinking transform not only companies but also cancer research? In this episode, Larry Kanarek, a retired senior partner from McKinsey & Company, joins Mitch Stoller to reflect on his high-stakes corporate work—most notably the transformation of Tyco—and the lessons he now brings to supporting lifesaving cancer research and advocacy. Larry talks with Mitch about his personal journey with chronic lymphocytic leukemia (CLL), including how pioneering cancer research and clinical trials gave him hope, time, and perspective. With insights from both the boardroom and the hospital room, Larry reminds us that progress happens when compassion and strategy work hand in hand. Episode Highlights: - Introduction to Strategic Thinking in Cancer Research - Larry Kanarek’s Journey to Consulting - The Tyco Transformation Story - Larry’s Personal Cancer Journey - Choosing Ibrutinib and a New Oncologist - Starting Ibrutinib and Clinical Trials - Achieving MRD Undetectable Status - Family Reactions and Support - Reflections on Cancer Research - Personal Stories and Family Influence - Impact of AI on Cancer Research - Closing Remarks and Gratitude Take Action: Support Cancer Research & Survivors - Donate to the AACR: Help advance the research that saves lives at https://AACR.org/Give - Share this episode: Someone in your network needs to hear Karlie’s story, so help us tell it by sharing it with them - Subscribe to Believe in Progress: Never miss a story that could inspire hope and action, you can find us on Apple Podcasts, Spotify, YouTube, or wherever you listen Production Credits: Host: Mitch Stoller Guest: Larry Kanarek Executive Producer: Anthony Lopes Executive Producer: Michael Leary Director: Anthony Lopes Creative Director/Director of Photography: Michael Leary Writer: Anthony Lopes Editor: Michael Leary Associate Producer: Heather Holland Believe in Progress is produced by CollegeCast LLC

Take Action: Help Accelerate Progress in Cancer Science and Medicine - Donate to the AACR: Fuel lifesaving innovation by supporting cutting-edge cancer research at https://AACR.org/Give - Share this episode: Inspire others by amplifying Karlie’s story of resilience and recovery in the face of cancer - Listen and subscribe: Find Believe in Progress on Apple Podcasts, YouTube, Spotify, or wherever you get your podcasts, and follow so you never miss an episode What does it take to survive cancer and still make it to the Olympics in a single year? In this inspiring episode of Believe in Progress, we sit down with Karlie Kisha: Olympian, papillary thyroid cancer survivor, and an assistant coach for the Villanova University field hockey team. Karlie takes us inside her incredible journey, from her cancer diagnosis just months before the Paris Olympic Games to representing the U.S. on the world stage. Her story is a masterclass in the power of determination, mindset, and belief in cancer research. Whether you're an athlete, a survivor, or someone in the midst of your own personal challenge, Karlie’s voice will remind you of what’s possible when you face adversity with courage and grace. Episode Highlights: Segment 1: Falling in Love with the Game Karlie shares her early passion for field hockey, her collegiate journey at the University of Connecticut, and how she set her sights on the Olympics. Segment 2: Diagnosis, Disruption, and Determination Just months before the Olympics, Karlie was diagnosed with papillary thyroid cancer. She discusses the whirlwind of emotions and the grit it took to keep her Olympic dreams alive. Segment 3: Recovery and Resilience From surgery to healing to elite-level competition, Karlie reflects on the physical and mental strength required to bounce back and perform on the sport’s biggest stage. Segment 4: Coaching, Mentorship, and the Next Chapter Now an assistant coach at Villanova, Karlie speaks about finding purpose beyond competition and why giving back means everything. Segment 5: Purpose, Gratitude, and Mental Toughness Karlie closes with reflections on gratitude, mental health, and how surviving cancer reframed her entire view on life and purpose. Take Action: Support Cancer Research & Survivors - Donate to the AACR: Help advance the research that saves lives at https://AACR.org/Give - Share this episode: Someone in your network needs to hear Karlie’s story, so help us tell it by sharing it with them - Subscribe to Believe in Progress: Never miss a story that could inspire hope and action, you can find us on Apple Podcasts, Spotify, YouTube, or wherever you listen Production Credits: Host: Mitch Stoller Guest: Karlie Kisha Executive Producer: Anthony Lopes Executive Producer: Michael Leary Director: Anthony Lopes Creative Director/Director of Photography: Michael Leary Writer: Anthony Lopes Editor: Michael Leary Associate Producer: Heather Holland Believe in Progress is produced by CollegeCast LLC.

Want to know how you can take action in the fight against cancer? Help the AACR accelerate progress: - Donate to the AACR: Fuel lifesaving innovation by supporting cutting-edge cancer research at www.AACR.org/Give. - Share this episode: Help amplify the message that strategic investments and scientific breakthroughs can change the future of cancer care. - Listen and subscribe: Find Believe in Progress on Apple Podcasts, YouTube, Spotify, or wherever you get your podcasts, and follow so you never miss an episode! In this episode of Believe in Progress, recorded live at the 2025 AACR Annual Meeting, we spotlight powerful stories of purpose, partnership, and personal experiences that propel action against cancer. Rodney and Erika McLeod, co-founders of Change Our Future, reflect on their personal cancer journeys and why they’re championing education, youth leadership, and cancer research through their growing partnership with the American Association for Cancer Research (AACR). NFL veteran and former Philadelphia Eagles safety Rodney McLeod shares how the loss of his grandmother to pancreatic cancer shaped his mission, while Erika opens up about her mother’s survivorship and their deep dedication to uplifting the next generation. We’re also joined by Stephen Ryan, President and Chairman of the AACR Foundation and longtime supporter of cancer research. Stephen discusses how personal loss became a catalyst for his advocacy and shares key insights about strategic giving, leadership, and the importance of funding early-stage research. Episode Highlights: Segment 1: Turning Loss into Purpose Rodney and Erika McLeod share how their personal connections to cancer inspired the founding of Change Our Future and their commitment to investing in the next generation. Segment 2: Partnering with the AACR to Inspire Young Scientists The McLeods speak about their involvement with the AACR’s high school program, empowering students to explore STEM and medical research as pathways to impact. Segment 3: Building Confidence Beyond the Classroom Through mentorship, leadership summits, and real-world skills, Change Our Future is equipping underserved youth with tools to succeed in life and career, including in cancer advocacy. Segment 4: Legacy, Strategy, and the Power of Philanthropy Stephen Ryan, President and Chairman of the AACR Foundation, discusses how cancer shaped his family’s legacy and how financial stewardship plays a key role in advancing cancer research. Segment 5: Broadening the Reach of Research Stephen reflects on the AACR’s reputation, the critical need to fund early-career scientists, and why the cancer research ecosystem must expand to reach more communities and have more potential. Production Credits: Host: Mitch Stoller Guests: Rodney McLeod, Erika McLeod, Stephen Ryan Executive Producer: Anthony Lopes Executive Producer: Michael Leary Director: Anthony Lopes Creative Director/Director of Photography: Michael Leary Writer: Anthony Lopes Editor: Michael Leary Associate Producer: Heather Holland Believe in Progress is produced by CollegeCast LLC.

In this powerful episode of Believe in Progress, John Matthews, founder of Ride Hard Breathe Easy, and Jack Owens, a University of Notre Dame student, share their deeply personal journeys to fight lung cancer through action, advocacy, and cycling. Segment 1: A Promise Becomes a Mission John shares how a promise to his mother led to Ride Hard Breathe Easy and its first cross-country fundraising ride. Segment 2: A New Generation Joins the Ride Jack Owens talks about his current 3,600-mile solo ride across the U.S., honoring his grandmother and expanding the organization’s impact. Segment 3: Meeting Patients Where They Are They discuss how funding helps lung cancer patients with transportation and essential needs, making treatment possible. Segment 4: Breaking the Stigma John addresses the stigma around lung cancer and the importance of educating the public about its realities. Segment 5: The Power of Family and Community Reflections on the role of family, community, and support networks in sustaining the mission. Segment 6: Training, Dedication, and Lessons Learned Jack shares his physical and emotional preparation for the ride, and what keeps him going on the toughest days. Segment 7: What’s Next for Ride Hard Breathe Easy If you enjoyed this episode, here is how you can take action to advance cancer research: • Donate to the AACR: Fuel lifesaving innovation by supporting cutting-edge cancer research at https://AACR.org/Give • Visit https://www.rhbe.org to learn more about Ride Hard Breathe Easy or to make a donation • Share this episode to raise awareness for cancer patients or with someone you know who might benefit from hearing it • Subscribe to Believe in Progress on Apple Podcasts, Spotify, YouTube, or wherever you listen to podcasts Production Credits Host: Mitch Stoller Guests: John Matthews and Jack Owens Executive Producer: Anthony Lopes Executive Producer: Michael Leary Director: Anthony Lopes Creative Director/Director of Photography: Michael Leary Writer: Anthony Lopes Editor: Michael Leary Associate Producer: Heather Holland Believe in Progress is produced by CollegeCast LLC.

In this emotional episode of Believe in Progress, host Mitch Stoller, Chief Philanthropic Officer at the AACR, is joined by Joe Krajewski, a father, runner, and advocate who transformed personal tragedy into a powerful mission. After losing his only child, Will, to osteosarcoma in 2016, Joe began running in Will’s memory as part of “Team Will Power,” raising vital funds and awareness in the fight against cancer. You will hear a deeply moving conversation, Joe reflects on love, grief, and legacy, and how a father’s promise has fueled ongoing advocacy, research support, and endurance racing. Whether you’ve experienced loss or simply want to be reminded of the strength of the human spirit, this episode will stay with you. Segment 1: A Father and Son Bonded by Running Joe shares heartfelt stories about his son Will—their special bond through running, Will’s contagious energy, and their memorable experience running the iconic Hood to Coast relay together. Segment 2: A Life-Altering Diagnosis Just weeks after Hood to Coast, Will was diagnosed with osteosarcoma. Joe recounts the moment of diagnosis, navigating treatments, and the endurance lessons that carried them through. Segment 3: Team Will Power and the Legacy of Advocacy The founding of Team Will Power marked a turning point. Joe explains how the team became a tribute to Will and a platform for cancer awareness, resilience, and generosity. Segment 4: Grief, Reflection, and the Endurance to Keep Going Joe opens up about living with grief, finding healing through running and writing, and how Will’s legacy continues to inspire his advocacy and outlook. Segment 5: The Meaning of Progress Joe reflects on the power of community, memory, and the AACR’s mission to advance lifesaving science—and what it means to ‘Believe in Progress.’ Take Action: Support Childhood Cancer Research Donate to the AACR: Fuel lifesaving innovation by supporting cutting-edge cancer research at https://AACR.org/Give Share this episode: Help spread Will’s story and honor the strength of families impacted by childhood cancer. Subscribe to Believe in Progress on Apple Podcasts, YouTube, Spotify, or wherever you enjoy podcasts. Production Credits Host: Mitch Stoller Guest: Joe Krajewski Executive Producer: Anthony Lopes Executive Producer: Michael Leary Director: Anthony Lopes Creative Director/Director of Photography: Michael Leary Writer: Anthony Lopes Editor: Michael Leary Associate Producer: Heather Holland Believe in Progress is produced by CollegeCast LLC.

In this special 50th episode of Believe in Progress, Mitch Stoller, the host of Believe in Progress and Chief Philanthropic Officer of the AACR, sits in the guest chair. Special guest host, Anthony Lopes, Esq., the executive producer of Believe in Progress, leads a reflective and inspiring retrospective conversation with Mitch. They discuss the early days of Believe in Progress, at the AACR, as well as moments that moved and transformed. This episode looks back at the voices, lessons, and stories that have shaped the show’s journey, as well as helped the AACR in the fight against cancer. We also hear about why there is still a lot more work to do in the battle against cancer, and why cancer research is so critical to that mission. Segment 1: Why Believe in Progress Matters - Mitch shares the origins of Believe in Progress, inspired by a desire to connect science with humanity and foster wider engagement. Segment 2: Episode One of Believe in Progress to Today - From Lauren Hart to marathon runners to trailblazing scientists, Mitch reflects on the evolution of the show and its mission. Segment 3: Behind the Mic - The guests and moments that left a lasting emotional imprint, including the late Howard Brown and Mitch’s own brother. Segment 4: Science + Philanthropy - Connecting real-world impact with groundbreaking research—and how storytelling builds bridges between them. Segment 5: The Guest Effect - What surprised Mitch most about guests’ honesty, vulnerability, and the unexpected ripple effects of each conversation. Segment 6: Looking Forward - From celebrity voices to younger scientists, Mitch shares his hopes and goals for the next 50 episodes and beyond. Segment 7: Why Progress Needs All of Us - A call to action to subscribe, share, and amplify the message: cancer research saves lives, and everyone has a role to play. Take Action: Support the Fight Against Cancer - Donate to the AACR: Fuel lifesaving innovation by supporting cutting-edge cancer research at https://AACR.org/Give - Share this episode: Help amplify the message that strategic investments and scientific breakthroughs can change the future of cancer care - You can show your support by following or subscribing to our show so that you never miss an episode! You can listen and subscribe to Believe in Progress on Apple Podcasts, YouTube, Spotify, or wherever you get your podcasts. Production Credits: Host: Anthony Lopes Guest: Mitch Stoller Executive Producer: Anthony Lopes Executive Producer: Michael Leary Director: Anthony Lopes Creative Director/Director of Photography: Michael Leary Writer: Anthony Lopes Editor: Michael Leary Associate Producer: Heather Holland Believe in Progress is produced by CollegeCast LLC.

This episode of Believe in Progress brings together two individuals leading global investments in cancer research: Dr. Christiana Bardon of MPM BioImpact and Mark Haefele of UBS Global Wealth Management. Dr. Bardon and Mr. Haefele are uniting science, finance, and philanthropy to accelerate breakthroughs in cancer treatment. Their collaboration has led to the Oncology Impact Fund, a revolutionary approach to investing in biotech innovation and expanding philanthropic support for cancer research. Featured Guests: Dr. Christiana Bardon – Managing Partner, MPM BioImpact Dr. Bardon shares how MPM BioImpact has helped launch more than 59 FDA-approved drugs and is driving cutting-edge therapies in oncology. She discusses the philanthropic vision behind the Oncology Impact Fund and the critical role the AACR research grant-giving program plays in supporting young scientists. Mark Haefele – Chief Investment Officer, UBS Global Wealth Management Mark discusses UBS’s commitment to purposeful investing, the genesis of the Oncology Impact Fund, and how clients responded to the idea of aligning financial returns with social good through impact investing. Key Topics: - The intersection of financial investment and cancer innovation - How impact investing can fund lifesaving research - The origins and structure of the Oncology Impact Fund - Why philanthropy and venture capital must work together - The role of AACR grants in nurturing the next generation of researchers Take Action: How You Can Support the Fight Against Cancer - Donate to the AACR: Fuel lifesaving innovation by supporting cutting-edge cancer research at https://AACR.org/Give - Share this episode: Help amplify the message that strategic investments and scientific breakthroughs can change the future of cancer care - Listen and subscribe: Find Believe in Progress on Apple Podcasts, YouTube, Spotify, or wherever you get your podcasts and make sure to follow/subscribe to our show so that you never miss an episode! Cancer Research Saves Lives® Production Credits: Host: Mitch Stoller Executive Producer: Anthony Lopes Executive Producer: Michael Leary Director: Anthony Lopes Creative Director/Director of Photography: Michael Leary Writer: Anthony Lopes Editor: Michael Leary Associate Producer: Heather Holland Believe in Progress is produced by CollegeCast LLC.

This special episode of Believe in Progress, recorded live at the AACR Annual Meeting 2025 in Chicago, features two compelling conversations that spotlight the human side of cancer research. From confronting rare diagnoses to reshaping clinical trials, our guests reveal how personal experience and advocacy are essential to scientific progress. Featured Guests Bill Day – Marketing Executive, Rare Cancer Survivor, AACR Foundation Board Member Bill shares his journey living with a rare and currently untreatable form of cancer, offering a deeply personal look at the stakes of research funding. As a communications expert and AACR board member, Bill reflects on what’s needed to better engage the public, drive bipartisan support, and sustain the momentum behind cancer science. Glenn Sykes – Metastatic Kidney Cancer Patient and Research Advocate Glenn discusses nearly a decade of living with metastatic kidney cancer and his role in reshaping how clinical trials include patient perspectives. He explores the vital role of the patient-oncologist relationship, how education empowers patients, and why researchers must listen more than ever. Key Themes · The power of patient advocacy in shaping cancer research and trial design · Personal resilience in the face of rare and advanced cancer diagnoses · Why storytelling matters in science communication and policy · The AACR Annual Meeting through the eyes of patients and advocates · A call for collective, nonpartisan action to protect cancer research funding Take Action: How You Can Support the Fight Against Cancer · Share your story: Your voice matters. Help advance research by sharing your cancer experience with others—and with your elected representatives. · Support the AACR: Visit https://AACR.org/Give to donate and fuel the next breakthrough in lifesaving science. · Subscribe and share: Find Believe in Progress on Apple Podcasts, Spotify, YouTube, or wherever you listen—and help spread hope. Cancer Research Saves Lives® Production Credits: Host: Mitch Stoller Executive Producer: Anthony Lopes Executive Producer: Michael Leary Director: Anthony Lopes Creative Director/Director of Photography: Michael Leary Writer: Anthony Lopes Editor: Michael Leary Associate Producer: Heather Holland Believe in Progress is produced by CollegeCast LLC.

This special episode of Believe in Progress, recorded live at the 2025 AACR Annual Meeting in Chicago, features dynamic conversations with researchers, clinicians, entrepreneurs, and student scholars, each contributing uniquely to the fight against cancer. From breakthrough diagnostics to trailblazing health services research, our guests share their stories of science, innovation, and hope. Featured Guests Dr. Marija Plodinec – CEO and Co-Founder of ARTIDIS Dr. Plodinec discusses how her background in physics led to a revolutionary approach in cancer diagnostics through nano-mechanical phenotyping. Learn how ARTIDIS is using atomic force microscopy to analyze tissue stiffness and improve treatment precision for solid tumors. Dr. Andrew Chapman – Director, Sidney Kimmel Cancer Center, Jefferson Health A leader in geriatric oncology and care delivery, Dr. Chapman emphasizes the importance of safe, high-quality care for all patients, especially older adults. He also reflects on the AACR’s impact as a convening force for breakthrough science. Izzy Wiener & Isaac Silverman – Student Researchers, Yeshiva University These future cancer researchers discuss their work in bioinformatics and molecular biology, presenting posters at the AACR Annual Meeting and sharing how their experiences shape their aspirations in medicine and research. Aaron Shaykevich – Scholar-in-Training Awardee & Incoming Medical Student, SUNY Upstate Aaron shares how his research into novel cancer markers is informed by his passion for public health and economics. He emphasizes the role of community insights and AI in future research directions. Take Action: How You Can Support the Fight Against Cancer - Donate to the AACR: Fuel lifesaving innovation by supporting cutting-edge cancer research at https://AACR.org/Give - Share this episode: Help amplify the message that bold ideas and cross-disciplinary thinking can change the future of cancer care - Listen and Subscribe: Find Believe in Progress on Apple Podcasts, YouTube, Spotify, or wherever you get your podcasts Cancer Research Saves Lives® Production Credits: Host: Mitch Stoller Executive Producer: Anthony Lopes Executive Producer: Michael Leary Director: Anthony Lopes Creative Director/Director of Photography: Michael Leary Writer: Anthony Lopes Editor: Michael Leary Associate Producer: Heather Holland Believe in Progress is produced by CollegeCast LLC. Check out more episodes: https://AACR.org/BelieveInProgress

What happens when deep science meets bold cancer-fighting innovation? In this episode of Believe in Progress, we sit down with Dr. Ajit Singh—Managing Director at Artiman Ventures and a Trustee of the AACR Foundation—for a compelling conversation about the technologies and ideas shaping the future of cancer care. With decades of experience leading both Fortune 500 healthcare companies and high-impact startups, Dr. Singh brings a unique perspective to the intersection of oncology, diagnostics, data science, and global health. From early detection and precision diagnostics to equitable access in underserved communities, his insights offer a powerful look at what’s next in the fight against cancer. In this episode, you’ll learn: - Why diagnostics and imaging are essential to improving patient outcomes - How venture capital is accelerating lifesaving cancer innovations - What it takes to bring bold ideas to market—and make them accessible globally - Why Dr. Singh believes in continuous learning, curiosity, and collaboration - What drives his commitment to the AACR Foundation’s mission Whether you're a scientist, entrepreneur, clinician, or advocate, this episode will inspire you to think bigger about what's possible in cancer care. Take Action: How You Can Support Cancer Research - Learn more about Dr. Ajit Singh’s work: Explore the ventures and companies he supports that are reshaping cancer diagnostics and care - Donate to the AACR: Fuel lifesaving innovation by supporting cutting-edge cancer research at https://AACR.org/Give - Share this episode: Help amplify the message that bold ideas and cross-disciplinary thinking can change the future of cancer care - Subscribe and listen: Find Believe in Progress on Apple Podcasts, YouTube, Spotify, or wherever you get your podcasts Cancer Research Saves Lives® Production Credits: Host: Mitch Stoller Guest: Dr. Ajit Singh Executive Producer: Anthony Lopes Executive Producer: Michael Leary Director: Anthony Lopes Creative Director/Director of Photography: Michael Leary Writer: Anthony Lopes Editor: Michael Leary Associate Producer: Heather Holland Believe in Progress is produced by CollegeCast LLC. Check out more episodes: https://AACR.org/BelieveInProgress

In this powerful and deeply personal episode of Believe in Progress, the podcast presented by the American Association for Cancer Research Foundation, host Mitch Stoller sits down with Chef AJ—renowned plant-based chef, bestselling author, and host of the popular YouTube channel "Healthy Living with Chef AJ." With over 47 years of experience in whole-food, plant-based nutrition, Chef AJ has long championed the power of healthy eating. But in early 2023, her journey took an unexpected turn with a stage 3 lung cancer diagnosis—an experience she publicly shared for the first time in November 2024. Now, Chef AJ is using her platform to speak candidly about cancer, nutrition, and what it means to live with purpose through adversity. This conversation explores: • Chef AJ’s transformation from “junk-food vegan” to whole-food advocate • Her surprising cancer diagnosis and the emotional aftermath • The evolving role of nutrition in cancer prevention and healing • How community, mindset, and hope fuel her journey today • What she’s learned from survivors, support groups, and sharing her platform Whether you’re navigating cancer, exploring a plant-based lifestyle, or searching for stories of resilience and hope—this is an episode you won’t want to miss. Don't forget to visit Chef AJ’s website and YouTube channel, to explore her books, including "Unprocessed" and "The Secrets to Ultimate Weight Loss," and access her “Thriving in the Face of Cancer” video series. If this episode moved you, here’s how you can make a difference: • Support cancer research by donating at AACR.org • Subscribe and leave a review on Apple Podcasts, YouTube, or wherever you listen • Share this episode with someone who might benefit from hearing Chef AJ’s story Also see: Chef AJ's Bestselling book: https://www.amazon.com/dp/B07JC8LHLZ?... Chef AJ's Amazon store: https://amazon.com/shop/chefaj Chef AJ's Social Media: Instagram: / therealchefaj Facebook: / chef.aj1 X: https://x.com/therealchefaj Production Credits: • Host: Mitch Stoller • Guest: Chef AJ • Executive Producer: Anthony Lopes • Executive Producer: Michael Leary • Associate Producer: Heather Holland • Director: Anthony Lopes • Creative Director/Director of Photography: Michael Leary • Editor: Michael Leary This episode is produced by CollegeCast LLC.

How can new approaches to early detection make a difference for children at risk of rare cancers? In this episode of Believe in Progress, brought to you by the American Association for Cancer Research (AACR) Foundation, host Mitch Stoller speaks with Dr. Kris Ann P. Schultz, a leading pediatric oncologist and Scientific Director of Cancer and Blood Disorders at Children's Minnesota. Dr. Schultz shares her groundbreaking work on DICER1-related cancers and how early diagnosis, surveillance, and collaboration with patients and families are transforming the field of pediatric oncology. From research-driven strategies to personal stories of survival, this episode explores how science and compassion intersect to save lives. Whether you're a healthcare professional, a caregiver, or an advocate for pediatric cancer research, this episode offers vital insights into how research is reshaping the future of childhood cancer care. In this episode, you’ll hear: - How Dr. Schultz’s personal drive led her into pediatric oncology - Why DICER1 research is critical for rare childhood cancers - How early detection and surveillance guidelines are changing lives - The vital role patients and families play in advancing research - Why survivorship care is essential for long-term wellness - How you can help drive progress in pediatric cancer research Timestamps: 00:00 Introduction and Mission Statement 00:15 Welcome to Believe in Progress 00:56 Meet Dr. Kris Ann Schultz 01:26 Dr. Schultz’s Career and Contributions 07:41 The Importance of Survivorship Care 12:49 Understanding ER One and DICER1 16:18 Early Detection and Surveillance Guidelines 22:32 Challenges and Future Directions 29:10 Conclusion and Wrap-up Additional information and contact information: - In 2024, the PPB/DICER1 Registry published updated DICER1 testing and surveillance guidelines in the journal of Clinical Cancer Research. This analysis demonstrated the impact of surveillance in PPB and Sertoli Leydig cell tumor and led to a recommendation for earlier initiation of ovarian surveillance in girls and young women with germline DICER1 variants. - READ MORE: https://aacrjournals.org/clincancerres/article/30/24/5681/750430/DICER1-Related-Tumor-Predisposition-Identification - Early detection efforts for individuals with DICER1-related tumor predisposition include patient and family education and age-specific imaging recommendations. - In rare cancers, every journey matters! Individuals impacted by these rare conditions are encouraged to learn more about DICER1 and to consider participation in efforts to advance our understanding of optimal treatments. - To contact the PPB/DICER1 and OTST Registries, please email dicer1@childrensmn.org. - To learn more about the PPB/DICER1 Registry please visit www.ppbregistry.org - To learn more about the OTST Registry please visit www.otstregistry.org Learn more and take action: - Visit aacr.org to donate and support pediatric cancer research - Subscribe and share this episode to spread awareness - For more episodes, visit aacr.org/BelieveInProgress Production Credits: Host: Mitch Stoller Guest: Dr. Kris Ann P. Schultz Executive Producer: Anthony Lopes Executive Producer: Michael Leary Associate Producer: Heather Holland Director: Anthony Lopes Creative Director/Director of Photography: Michael Leary Editor: Michael Leary This episode is produced by CollegeCast LLC. Cancer Research Saves Lives® Listen and subscribe on Apple Podcasts, YouTube, or wherever you get your podcasts.