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Tiny Matters

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Science shapes every facet of our lives, but so much of its influence is overlooked or buried in the past. Tiny Matters is an award-winning science podcast from the American Chemical Society about tiny things — from molecules to microbes — that have a big and often surprising impact on society, past and present. From deadly diseases to forensic toxicology to the search for extraterrestrial life, hosts and former scientists Sam Jones and Deboki Chakravarti embrace the awe and messiness of science and its significance, asking questions like, "how was IVF invented?," "what do glaciers tell us about Earth’s ancient past?," and "why is smallpox the only human infectious disease we’ve eradicated?" New episodes every Wednesday wherever you listen to podcasts.


161 Episodes
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Chain Reaction is a new podcast from the American Chemical Society that links chemistry’s past to its future, revealing how this ever‑evolving science shapes the world around us, from the materials we use every day to the environment that we depend on. Each episode brings fresh perspectives and personal stories from chemists, engineers, and other scientists, as well as historians who guide us through pivotal moments in chemistry’s history. Together, we’ll uncover chemistry’s surprising connections, explore its interdisciplinary impact, and see how past discoveries set off the breakthroughs of today and the future. Whether you’re a student, an experienced scientist, or simply curious, Chain Reaction will show you how chemistry fits into the bigger picture — and why it matters now more than ever. Subscribe wherever you listen to podcasts! acs.org/chainreactionExec producer: Sam JonesProducer: Margot WohlResearcher: Bec RoldanProduction support: Michael David and Matthew RadcliffCover art: Joe ButeraSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
We want to recommend a new podcast called The Interface. It's the BBC's fiercly informed, fast and funny take on how tech is impacting all of us. We have become regular listeners and hope you enjoy it too!
In this episode of Tiny Show and Tell Us, we go from nerdy house-party physics to the brutal realities of morning sickness (can you say range!). First, we unpack what 5D data storage is and debate what we’d personally toss into the “Memory of Mankind” salt mine in Austria. Then we tackle a listener’s question about whether science has any updates on what causes severe morning sickness. We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org *or fill out this form* with your favorite science fact or science news story for a chance to be featured.A transcript and references for this episode can be found at acs.org/tinymatters.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
In 2019, Nathan Hudson-Peacock was serving as an expedition doctor to a group hiking in the Indian Himalayas. At around 17,000 feet, a climber suddenly went from having a mild headache to a life‑threatening cerebral edema. On top of that, a storm was closing in. So, what did he do? How do expedition doctors keep people alive in the harshest places on Earth? Tune in to this week’s episode to find out. In it, we chat with Nathan as well as high altitude physician Monica Piris, who has spent much of her time on Everest. We dig into the world of expedition medicine: the preparation, the danger, the breathtaking environments, and the moments that can reshape your understanding of the planet and the impact of climate change. Listen to American Medieval: https://americanmedieval.com/Send us your science facts, news, or other stories for a chance to be featured on an upcoming Tiny Show and Tell Us bonus episode. And, while you're at it, subscribe to our newsletter!All Tiny Matters transcripts and references are available here.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
In this episode of Tiny Show and Tell Us, we talk about the crafty corvids that steal anti‑bird spikes to build chaotic, spiky nests and “Mitochondrial Eve” — the most recent common maternal ancestor of modern humans. Get ready for stories of sandwich‑stealing gulls, Deboki being held hostage by a peacock, and the Mitochondrial Eve/Y Chromosomal Adam romcom no one asked for.We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org *or fill out this form* with your favorite science fact or science news story for a chance to be featured.A transcript and references for this episode can be found at acs.org/tinymatters.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
For over a thousand years, humans have been harnessing wind energy. It may have begun with small, grain‑grinding windmills in ancient Persia, but today you might spot Hoover‑Dam‑sized offshore turbines as you drive along the east coast. How did we get here? In this episode of Tiny Matters, we explore the first electric wind turbines built in the late 1800s, how government policies in the 1970s and ’80s shaped the modern wind industry, and why giant offshore wind farms are suddenly in the news. We also clear up misinformation stemming from a Hollywood blockbuster as well as what we know about the impact of wind farms on whales, birds and bats.Send us your science facts, news, or other stories for a chance to be featured on an upcoming Tiny Show and Tell Us bonus episode. And, while you're at it, subscribe to our newsletter!All Tiny Matters transcripts and references are available here.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
In this episode of Tiny Show and Tell Us, we explore a listener’s tip about a new source of tire rubber — the Russian dandelion — and the science behind what makes it such an incredible and sustainable source of natural latex rubber. Then we answer a listener’s question about a vaccine for fentanyl that will stop the drug from reaching the brain, preventing overdose.We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org *or fill out this form* with your favorite science fact or science news story for a chance to be featured.A transcript and references for this episode can be found at acs.org/tinymatters.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
In 1599, a family in a small French town claimed that their daughter was possessed by a demon called Beelzebub and, despite daily exorcisms, the demon possessing this woman was staying put. So France’s Henri IV set up a royal commission that would try something a little different. The woman would still receive exorcisms, complete with the normal exorcism accoutrements, but with a catch. The priest wouldn’t actually be Catholic, the water in the vessel would be ordinary water, and the Latin used wouldn’t be religious — it would be from Virgil’s famous poem Aeneid. That's because this wasn't actually an exorcism. It was an experiment built on a deceptively simple tool that scientists and doctors still use today to study new medical treatments: a placebo.In this episode, we explore the surprising origins and evolution of one of modern medicine’s most important tools: the clinical trial. We follow the development of experimental design across centuries to modern day randomized controlled trials and the debates about their limitations, trying to answer the question, “How do we know whether a treatment truly works?”Send us your science facts, news, or other stories for a chance to be featured on an upcoming Tiny Show and Tell Us bonus episode. And, while you're at it, subscribe to our newsletter!All Tiny Matters transcripts and references are available here.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
In this episode of Tiny Show and Tell Us, we learn that humans aren’t the only mammals who menstruate. We explore the fulvous fruit bat’s 33‑day cycle, how reproductive biology differs across species, and why scientists still don’t fully understand why menstruation evolved in the first place. Then we take a deep dive into the world of mycotoxins: dangerous compounds produced by fungi. We cover how these toxins form, why they’re so hard to eliminate, and risks they pose to agriculture, livestock, and human health.We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org *or fill out this form* with your favorite science fact or science news story for a chance to be featured.A transcript and references for this episode can be found at acs.org/tinymatters.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
It’s no exaggeration to say that polio shaped modern medicine. Before a vaccine was available, polio outbreaks left thousands of people paralyzed, with some unable to breathe. But, in 1928, the development of the iron lung meant that, for the first time, humans could rely on a machine to stay alive. In this episode, we trace the rise of polio in the early 20th century, the science behind the virus, and the race to save lives. From early resuscitation experiments to the unexpected inspiration behind the iron lung, we uncover the innovation, ethical dilemmas, and human stories that defined this era, hearing from two people whose early childhoods and families were dramatically shaped by the disease. Send us your science facts, news, or other stories for a chance to be featured on an upcoming Tiny Show and Tell Us bonus episode. And, while you're at it, subscribe to our newsletter!All Tiny Matters transcripts and references are available here.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
In this episode of Tiny Show and Tell Us, we kick things off with a quick shout-out to a listener who started flossing thanks to a previous episode. Then we dive into the hidden history of the women “computers” at Harvard Observatory, including Henrietta Leavitt, who laid the foundation for modern astronomy with her groundbreaking discoveries including calculating the size of the Milky Way. Then we discuss the co-evolutionary arms race between passion vines and Heliconius butterflies, which includes fake eggs, toxic fruit, and impaled caterpillars.We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org *or fill out this form* with your favorite science fact or science news story for a chance to be featured.A transcript and references for this episode can be found at acs.org/tinymatters.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
In this milestone 100th episode of Tiny Matters we take you on a personal journey into what first inspired our passion for science. Sam shares the story of her childhood struggle with germophobia and the brain-altering bacteria that kicked it off, likely causing a condition called PANDAS: Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections. PANDAS may have led to her OCD, but it also fueled Sam’s fascination with the microscopic world, germ theory, and the ways infections can shape our brains. Then Deboki dives into her early fascination with vaccines, inspired by the interests of her scientist parents. She shares the history of the polio vaccine — a story of victory but also tragedy that led to significant progress, both in terms of science and safety.Send us your science facts, news, or other stories for a chance to be featured on an upcoming Tiny Show and Tell Us bonus episode. And, while you're at it, subscribe to our newsletter!All Tiny Matters transcripts and references are available here.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
In this episode of Tiny Show and Tell Us, we read an email from “baby sis” aka Binky aka Sam’s younger sister Caroline who writes in about an alarming pregnancy test that predates today’s at-home tests. Then we talk about a fascinating study that found a dead salmon showed brain activity in an MRI machine. Spoiler: It wasn’t actually alive, scientists just really needed to rethink MRI analysis. We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org *or fill out this form* with your favorite science fact or science news story for a chance to be featured.A transcript and references for this episode can be found at acs.org/tinymatters.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Not a fan of daylight saving? Beyond the depressingly early sunsets, that may be because it’s messing with your circadian clock. In this episode of Tiny Matters, we ask, “How do organisms — from bacteria to sea anemones to humans — keep track of time?” We talk about circadian clocks and how both internal molecular changes and environmental cues called “zeitgebers,” which include things like light and food, synchronize biological rhythms and help all of us survive.Send us your science facts, news, or other stories for a chance to be featured on an upcoming Tiny Show and Tell Us bonus episode. And, while you're at it, subscribe to our newsletter!All Tiny Matters transcripts and references are available here.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
In this episode of Tiny Show and Tell Us, we read an email from a listener who, as a kid, shared a fun fact with her classroom: polar bears have black skin. Her teacher not only told her she was wrong but embarrassed her in front of the other students. Well, it’s time to set the record straight. Polar bears do, in fact, have black skin and we do, in fact, love a grudge and are so glad to provide vindication. Then we talk about the hidden world of insect vibrational communication.We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org *or fill out this form* with your favorite science fact or science news story for a chance to be featured.A transcript and references for this episode can be found at acs.org/tinymatters.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
In today’s episode, we chat with author Sam Kean about his new book Dinner with King Tut and learn how researchers and citizen scientists are recreating ancient recipes, tools, and technologies — from wound remedies with pennies to inventive pottery glazed in blood — and how experimental archaeology is changing our understanding of the past. Send us your science facts, news, or other stories for a chance to be featured on an upcoming Tiny Show and Tell Us bonus episode. And, while you're at it, subscribe to our newsletter!All Tiny Matters transcripts and references are available here.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
In this episode of Tiny Show and Tell Us, we talk about different ways of turning pennies all of the colors of the rainbow. Then we discuss an ongoing NASA mission to touch the sun.We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org *or fill out this form* with your favorite science fact or science news story for a chance to be featured.A transcript and references for this episode can be found at acs.org/tinymatters.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Most of us know the story of the Titanic. In 1912, the massive — supposedly indestructible — steamship sank after hitting an iceberg on its first and only journey across the Atlantic Ocean. Titanic remained undiscovered on the seafloor, somewhere in the North Atlantic Ocean, for 73 years, until it was found nearly two miles beneath the surface. But now the ship might be disappearing again, this time for good. And the culprit is not another iceberg — it’s something much, much smaller.Send us your science facts, news, or other stories for a chance to be featured on an upcoming Tiny Show and Tell Us bonus episode. And, while you're at it, subscribe to our newsletter!All Tiny Matters transcripts and references are available here.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
As we approach episode 100 of Tiny Matters, we wanted to talk about how it all got started nearly 4 years ago and where we are headed! How did Sam and Deboki become co-hosts? What have they learned about the types of stories and episodes they are drawn to? What happens if an interview goes poorly? What is the American Chemical Society (ACS)? How about Multitude? Will we get 100 MORE episodes of the show? And more... See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
If you’re a female and you want to use a contraceptive pill, patch, injection, or device, you have over 250 options. But if you’re a male and you want a contraceptive, you have three options. You can get a vasectomy, you can use condoms, which can have up to a 18% failure rate, or you can use what sex researchers politely call “the withdrawal method,” which is highly unreliable. But there could be another male contraceptive very soon. So what took so long?Send us your science facts, news, or other stories for a chance to be featured on an upcoming Tiny Show and Tell Us bonus episode. And, while you're at it, subscribe to our newsletter!Links to the Tiny Show and Tell stories are here and here. All Tiny Matters transcripts and references are available here.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
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Comments (3)

A.J

🤯👍

Nov 24th
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A.J

great podcast with very informative episodes👍👍👍

Nov 23rd
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Sahand Bahari

clear explanations, amazing facts, very inspiring for anyone interested in a scientific career.

Feb 12th
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