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Brains & Guts: The GI Innovation Podcast
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Brains & Guts: The GI Innovation Podcast

Author: American College of Gastroenterology

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In each episode of Brains & Guts, we interview gastroenterology innovators and inventors to unpack their successes, pitfalls, and learnings. The goal? Empower individual gastroenterologists with the skills to explore ideas and apply the innovator’s mindset to everyday practice.
13 Episodes
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In this episode, Dr. Austin Chiang walks us through the industry's perspective on AI innovation and patient care in gastroenterology. The conversation covers lessons learned from deploying AI tools in the endoscopy suite, barriers to widespread adoption, what role physicians should play in the design and testing of new AI applications, and how to conduct research in the AI age, given how fast leaps in innovation are happening. (20:36)
In this episode, Dr. Brennan Spiegel explains his vision for ethically sound, patient centered AI. As he describes, the future of AI in GI could bring us unparalleled cancer prevention and personalized treatments – but to achieve that vision, we need to tackle the ethical considerations now. Our conversation also covers thorny AI questions, like informed consent, accountability and malpractice, monitoring bias, data ownership, and more. (35:29)
In this episode, Dr. Keswani walks us through how to approach implementing computer-aided polyp detection (CAD-E), including measuring the specific impact of AI on quality, obtaining buy-in from peers and leadership, adopting CAD-e as the standard of care, even without a specific billing code and addressing challenges, like the long lead-time between implementation and results. (28:16)
In season 2 of Brains & Guts, we're focusing on the AI landscape in GI. For this first episode, we are joined by Dr. Aasma Shaukat, professor of medicine at NYU Grossman School of Medicine, a member of ACG's Board of Trustees, and a thought leader on effective and ethical use of AI tools. In the conversation, she offers her insights on how AI might accelerate precision medicine initiatives for colorectal cancer prevention, the impact of automated 'back-office' operations on provider well-being and burnout, and ACG's approach to managing ethical considerations, health equity, and industry collaboration. (38:20)
In this final episode of season 1, Dr. Vladimir Kushnir takes a look back at all the great advice from our guests. We cover the beginning of the innovation journey, fundraising, patenting, prototyping, building a team, and more. New episodes coming in 2025! (13:45)
In this episode, we are joined by Steven Fallon, JD, a shareholder at Greer, Burns & Crain in Chicago and an intellectual property expert. Steven explains why freedom to operate analyses are crucial before manufacturing and sales. The conversation also covers: how FTO differs from patentability, how to conduct an analysis and mitigate risks, and why intellectual property law can actually help you compete against big businesses. (30:57)
In this episode, we are joined by Christen Springs, the Managing Partner of EndoRx and a 20 year veteran of the medical device industry. Christen walks us through the importance of prototyping, including how to identify builders, key benchmarks for budget and timelines. We also explore how prototypes can be more important than patents in securing investments.(27:36)
In part two of this episode, the entrepreneurs behind Monarc Partners - Jason Ylizarde, Jeremy Starkweather, and John Wynne - share more secrets about fundraising and market analyses. The conversation includes whether physicians should invest their own money, how to build a team, and the top mistakes innovators make during the fundraising and licensing process. (27:28)
In this two-part episode, the entrepreneurs behind Monarc Partners - Jason Ylizarde, Jeremy Starkweather, and John Wynne - share the secrets behind the conducting a market analysis, fundraising, and the commercialization process. The conversation includes how to assess your innovation's market size, the factors to consider in your risk evaluation, and what an inventor should do before pitching a product for outside capital. (30:46)
In this episode, Robert Takara, JD from City of Hope answers all of the questions that aspiring GI innovators are afraid to ask but need to know. The conversation covers the different types of patents and how they apply to gastroenterology, why provisional patents are important, when to engage a patent attorney or an institution's technology transfer program, and the top legal mistakes that innovators make. (26:57)
In this episode, Steven Edmundowicz, MD helps aspiring GI innovators gut check their potential financial questions. Dr. Edmundowicz walks through the risk-benefit calculation for a product development journey, evaluating market size, the 'code / no-code' question, starting a company versus prototyping & licensing, and more. (23:34)
In this episode, we are joined by Virender Sharma, MD, FACG, a entrepreneur and founder of several med-tech companies. Dr. Sharma walks us through the key steps that come at the beginning of the innovation journey: identifying a need, evaluating novelty, establishing legal protection, and most importantly, understanding your why as an innovator.(31:07)
Why Innovate In GI?

Why Innovate In GI?

2023-10-1717:08

In this first episode of Brains & Guts, our hosts – Drs. Vivek Kaul, Toufic Kachaamy, and Vladimir Kushnir – explain why the practicing gastroenterologist should care about innovation. The conversation also defines the innovator’s mindset, the role of industry companies, and what topics the show will cover in Season 1.(17:08)
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