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PT Cubed
PT Cubed
Author: Dr. Nate Karam, PT, DPT, CSCS
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© Dr. Nate Karam, PT, DPT, CSCS
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Hosted by Dr. Nate Karam, PT, DPT, CSCS, the PT³ Podcast brings real talk from the front lines of rehab, strength, and sports performance.
From injury recovery to chasing PRs, each episode delivers sharp, evidence-based insight with guest experts including physical therapists, athletic trainers, professors, athletes and other professionals in sports medicine.
Whether you're a lifter, clinician, or just a human being with a moving body - I can guarantee that there's something here for you!
📸 IG: @ptcubed
🌐 ptcubed.com
📬 natekaram@ptcubed.com
Strength. Rehab. Performance.
From injury recovery to chasing PRs, each episode delivers sharp, evidence-based insight with guest experts including physical therapists, athletic trainers, professors, athletes and other professionals in sports medicine.
Whether you're a lifter, clinician, or just a human being with a moving body - I can guarantee that there's something here for you!
📸 IG: @ptcubed
🌐 ptcubed.com
📬 natekaram@ptcubed.com
Strength. Rehab. Performance.
23 Episodes
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The claim that your body can only “use” 20–30 grams of protein per meal is one of the most repeated rules in fitness.It sounds scientific. It sounds precise. And it’s often misunderstood.In this episode of the PT³ Podcast, I break down what that claim actually refers to, what muscle protein synthesis really measures, what happens to protein above the so-called limit, and what actually matters if your goal is hypertrophy and performance.You’ll learn the difference between acute MPS and whole-body protein utilization, why oxidation does not mean wasted, how total daily intake compares to per-meal precision, and how to apply protein guidelines without turning nutrition into anxiety.This episode is designed to be evidence-based, practical, and immediately actionable whether you’re tracking macros, coaching clients, cutting, bulking, or just trying to build muscle intelligently.In this episode, we cover:• What muscle protein synthesis (MPS) actually measures• Why the “30 gram limit” is an oversimplification• The difference between MPS, whole-body protein turnover, and nitrogen balance• The evidence behind 0.3–0.5 g/kg per meal• What happens to protein above the MPS plateau• Why total daily protein intake drives hypertrophy• The evidence supporting 1.6–2.2 g/kg/day• How to distribute protein across 3–5 meals• Practical protein guidelines you can apply immediatelySponsors:This episode is sponsored by Pocket Prep.If you’re studying for the NPTE, CSCS, TSAC-F, or another board or certification exam, Pocket Prep’s question-based format helps reinforce mechanisms, not just memorization. Their platform is built around consistent exposure and active recall so you can build true retention over time.You can get started using my unique link here:👉 https://pocketprep.sjv.io/xLAPzkUse code PTCUBED10 where applicable for discounts or premium upgrades.This episode is also sponsored by Bucked Up.Whole food protein should be your foundation, but high-quality supplements can help support consistency when daily intake is difficult to hit through food alone. I regularly use Bucked Up’s protein, creatine, and performance supplements because they align with evidence-based dosing and quality standards.You can get 20% off your entire order with code ptcubed3 at checkout.Connect with me:Website: https://ptcubed.comInstagram: @ptcubedEmail: natekaram@ptcubed.comIf this episode helped simplify protein and cut through the noise, share it with someone who’s overthinking macros and underthinking fundamentals, and make sure you’re subscribed so you don’t miss what’s coming next.Strength. Rehab. Performance.
Most training plateaus, injury flare-ups, and frustrating setbacks aren’t just a load problem. They’re often a capacity problem.In this episode of the PT³ Podcast, I break down what capacity actually is, far beyond just strength or fitness, and how it applies across training, rehab, and coaching. You’ll learn how your tissues, recovery, stress, and lifestyle all influence what your body can tolerate, why the same program works for one person and not another, and how to build capacity so progress becomes more sustainable.This episode is designed to be dense, practical, and immediately useful, whether you’re lifting, running, returning from injury, or just trying to feel stronger and more capable in your body.In this episode, we cover:What “capacity” really means in human performanceThe difference between tissue, work, physiological, and psychological capacityWhy injuries often happen when capacity lags behind loadHow sleep, nutrition, and stress directly impact your training capacityWhy avoiding movement can lower capacityHow graded exposure builds resiliencePractical rules for progressing volume and intensityActionable ways to build capacity starting this weekSponsors:This episode is sponsored by Pocket Prep, and they’re currently running a free 30-Day Study Challenge designed around one small, realistic action per day to build focus, consistency, and study capacity that actually lasts. The challenge runs February 16 - March 18.You can sign up for the free challenge using my unique link here:👉 https://pocketprep.sjv.io/xLAPzkIf you want extra support, you can upgrade to the VIP experience, which includes a free month of Pocket Prep Premium, study groups, and a session with a subject-matter expert.Use code PTCUBED10 for $10 off the VIP experience.This episode is also sponsored by Bucked Up.I regularly use Bucked Up’s pre-workout, creatine, protein, protein sodas, and other supplements, and I recommend them to my entire audience because they support training and recovery without relying on hype or gimmicks.You can get 20% off your entire order with code ptcubed3 at checkout.Connect with me:Website: https://ptcubed.comInstagram: @ptcubedEmail: natekaram@ptcubed.comIf this episode helped you think differently about training or rehab, share it with someone who feels like they’re working hard but not progressing, and make sure you’re subscribed so you don’t miss what’s coming next.
Most training plateaus, injury flare-ups, and frustrating setbacks aren’t random, and they’re not because you’re unmotivated or broken.They’re often a load problem.In this Season 3 opener of the PT³ Podcast, I break down what load actually is, far beyond just weight on a bar, and how it applies across training, rehab, and coaching. You’ll learn how stress, recovery, and capacity interact, why progress stalls even when effort is high, and how to make smarter adjustments instead of guessing.This episode is designed to be dense, practical, and immediately useful, whether you’re lifting, running, returning from injury, or just trying to feel better and more capable in your body.In this episode, we cover:What “load” really means in the context of human performanceThe most common ways people mismanage loadWhy motivation often outpaces tissue capacityHow load applies the same way in training, rehab, and coachingPractical frameworks to adjust load without overcorrectingHow to use symptoms as information instead of instructionsSponsorsThis episode is sponsored by Pocket Prep, and they’re currently running a free 30-Day Study Challenge designed around one small, realistic action per day to build focus, consistency, and study habits that actually last. The challenge runs February 16 - March 18.You can sign up for the free challenge using my unique link here:👉 https://pocketprep.sjv.io/xLAPzkIf you want extra support, you can upgrade to the VIP experience, which includes a free month of Pocket Prep Premium, study groups, and a session with a subject-matter expert.Use code PTCUBED10 for $10 off the VIP experience.This episode is also sponsored by Bucked Up.I regularly use Bucked Up’s pre-workout, creatine, protein, protein sodas, and other supplements, and I recommend them to my entire audience because they support training and recovery without relying on hype or gimmicks.You can get 20% off your entire order with code ptcubed3 at checkout.Connect with meWebsite: https://ptcubed.comInstagram: @ptcubedEmail: natekaram@ptcubed.comIf this episode helped you think differently about training or rehab, share it with someone who feels stuck, and make sure you’re subscribed so you don’t miss what’s coming next.
As the year comes to a close, this episode is a pause.No highlight reel. No hot takes. Just an honest reflection on the work that happened behind the scenes. The long days, the quiet discipline, and the pressure that shaped growth when nothing felt fast or flashy.In this solo episode, I reflect on what this year demanded mentally, physically, and professionally. We talk about patience, alignment, and what it really costs to build something meaningful when the progress isn’t always visible.I also share an important announcement about the future of the PT³ Podcast, including new sponsor partnerships heading into 2026.If you’re ending the year feeling tired, proud, uncertain, or somewhere in between, this episode is for you.Thanks for being here.Let’s close the year strong!
In this episode, I sit down with my longtime friend and the man who unknowingly set PT³ in motion - John Thomas, better known online as The Bodybuilding Vegan. We dive deep into how he built serious muscle on a plant-based diet, the science behind optimizing performance without animal products, and the mindset it takes to stay disciplined in a world full of shortcuts. From undergrad memories to modern-day fitness philosophies, this one’s packed with stories, strategy, and straight-up inspiration.Listen in if you’ve ever wondered:Can you actually build muscle on a vegan diet?What supplements matter most for plant-based lifters?How can you train with purpose and still enjoy life outside the gym?Join the PT³ movement:Website: www.ptcubed.comInstagram: @ptcubedEmail: natekaram@ptcubed.comCheck out my coaching programs, grab your PT³ guidebooks, and tune into more episodes that bridge the gap between rehab and performance.Join the PT³ Padawans and unlock your true potential.
When life gets loud, most people lose their focus. Not because they don’t care, but because they’ve never learned how to truly lock in.In this episode, Dr. Nate breaks down the mindset and strategy behind what he calls The Great Lock-In. You’ll learn how to filter distractions, build tunnel vision for your goals, and create a routine that keeps you moving forward even when everything around you feels chaotic.This episode is about more than fitness. It’s about clarity, consistency, and becoming the kind of person who follows through no matter what.Connect with Nate:🌐 Website: www.ptcubed.com📧 Email: natekaram@ptcubed.com📲 Instagram: @ptcubed
In this incredibly special guest episode of the PT³ Podcast, I sit down with Ryan Gardner, CEO and founder of Bucked Up, to unpack what it really takes to build a fitness brand from scratch and scale it into one of the most recognized supplement companies today. Ryan opens up about the entrepreneurial journey, the challenges of growth, and the vision that continues to drive Bucked Up forward.We also dive deep into the clinically proven benefits of supplementation - from performance to recovery, and discuss why Bucked Up stands out as the best choice for all your gym supplement needs. Whether you’re an athlete, coach, or entrepreneur, you’ll walk away with valuable insights on business, training, and fueling your body for success.👉 Follow along for more strength, rehab, and performance content on Instagram: @ptcubed👉 Explore my coaching and resources at ptcubed.com👉 Questions or collabs? Reach me at natekaram@ptcubed.comJoin the PT³ Padawans and unlock your true potential.Check out Ryan's socials: @buckedupceo on IG and TikTok - use code CEO20 at checkout for 20% all Bucked Up products!
Something massive is on the way. In just two weeks, I’ll be dropping one of the biggest PT³ Podcast episodes yet - my interview with Ryan Gardner, founder of Bucked Up.In this short teaser, I’ll share why this conversation matters, what you can expect, and how Ryan’s story connects to your own journey as a student, athlete, or professional. From building one of the fastest-growing supplement brands to lessons on mindset, resilience, and vision... this is an episode you won’t want to miss.👉 Don’t miss future episodes - hit follow and leave a review on the PT³ Podcast.👉 Prep smarter for any exam in any profession with Pocket Prep - use my link https://pocketprep.sjv.io/4GDDzo to sign up and begin studying!👉 Fuel your training with Bucked Up - use code NBK32 for 20% off at checkout at buckedup.com.👉 Join the PT³ Padawans and unlock your true potential at ptcubed.com.👉 Follow me on Instagram @ptcubed for daily content on strength, rehab, and performance.
Protein isn’t just for bodybuilders - it’s the foundation of recovery, strength, hormones, immunity, and even healthy aging. In this episode, Dr. Nate Karam breaks down protein in simple, science-backed terms. You’ll learn:What protein actually does in your body (beyond muscle).How much protein you really need (and why nutrition labels mislead you).The role of branched-chain amino acids and why leucine is the MVP.How to choose a quality protein supplement and why Bucked Up Buck Feed Whey checks all the boxes.The truth about plant-based protein and how vegans can build muscle just as effectively.Common myths debunked (protein and kidneys, “too much protein,” and more).Practical food examples and takeaways for every lifestyle.Stay tuned until the end for a preview of two huge upcoming episodes: Ryan Gardner, CEO of Bucked Up, and John the Bodybuilding Vegan.Whether your goal is strength, performance, or longevity - this is your ultimate protein guide.Connect with me:Instagram: @ptcubedWebsite: ptcubed.comEmail: natekaram@ptcubed.comSave 20% at Bucked Up with my code NBK32
From tingles to pump claims, pre-workout powders promise a lot - but do they actually deliver? In this episode, Dr. Nate breaks down the science behind five of the most common ingredients: caffeine, beta-alanine, citrulline malate, tyrosine, and arginine.We’ll cover:Which ingredients actually improve strength or enduranceWhich ones only work with long-term useWhich are mostly hypeHow to dose them for real resultsNo gimmicks, no fluff — just evidence-based answers so you know exactly what’s in your scoop.Connect with me:Instagram: @ptcubedWebsite: ptcubed.comEmail: natekaram@ptcubed.com
Is 8–12 reps really the “hypertrophy zone”? Does strength only come from heavy weights? In this episode, Dr. Nate breaks down the clinical science behind rep ranges - and why effort, not just load, is the real driver of gains.We dig into the evidence from Schoenfeld’s 2021 narrative review and 2017 meta-analysis to dissect the classic repetition continuum. Whether you’re training for strength, hypertrophy, or endurance, this episode gives you the why behind the how - no fluff, all muscle.📚 Research ReferencedSchoenfeld et al. (2021): Loading Recommendations for Strength, Hypertrophy, and EnduranceSchoenfeld et al. (2017): Effects of Resistance Training with Different Loads on Muscle Hypertrophy and Strength🔥 Ready to train smarter and harder?Join the PT³ Padawans:🔗 Website: ptcubed.com📩 Email: natekaram@ptcubed.com📱 Instagram: @ptcubed
In this quick but powerful episode, Dr. Nate Karam breaks down why creatine isn’t just a “gym bro” supplement - it’s one of the most well-researched tools for building strength, boosting cognitive performance, and aging like a beast.Backed by three major systematic reviews, this episode covers:How creatine increases strength and muscle massThe underrated brain benefits for memory and focusIts role in protecting muscle and function as we agePractical tips on dosing, timing, and what type to buyWhether you're lifting heavy, juggling a hectic schedule, or just trying to stay sharp and strong through the years - this episode gives you the full picture on creatine and how to use it right.
In this episode, we continue our Maximizing Your Gains series by diving into Chapters 4 through 6 of the PT³ Strength Training Guidebook. We’ll break down some of the most misunderstood — but absolutely essential — pillars of building muscle and strength:✔ The difference between training volume and intensity, and why getting this wrong can stall your progress✔ How to make smart, effective exercise selections based on your goals and experience level✔ The real science behind training frequency and recovery, and how to avoid the trap of overtraining or under-recoveringWhether you're chasing your first real strength gains or trying to bust through a plateau, this episode will help you train smarter, stay consistent, and actually see results.Grab the full PT³ Strength Training Guidebook at ptcubed.com to follow along, and don’t forget to hit follow so you never miss an episode.
Welcome to the first official episode of the PT³ Podcast — where physical therapy, personal training, and podcast talks collide. We’re kicking things off by diving into the first three chapters of Maximizing Your Gains, my premium guide for anyone serious about training smarter and building lasting strength - available to purchase on ptcubed.com/shop.This episode covers:Chapter 1: What is Strength?We define strength in practical, scientific terms — not just what it looks like, but what it does for you in training, rehab, and everyday life.Chapter 2: The SAID PrincipleYour body adapts to exactly what you do — nothing more, nothing less. We explore how to harness the “Specific Adaptation to Imposed Demands” to make training efficient and effective.Chapter 3: Progressive OverloadThis is the bedrock of muscle and strength development. We break down how to increase demand over time without burning out or plateauing.Joining me on the mic is Drew Zitomer, CSCS — a fellow strength and conditioning specialist, soon-to-be Occupational Therapist, passionate coach, and lifelong lifter who knows his way around a barbell and a brain. Drew brings a hybrid approach to coaching that blends rehab science with high-performance training, and in this episode, he shares his personal take on what it really means to train with purpose.PT³ coaching clients get free access to the full Maximizing Your Gains guide. Want in? Head to ptcubed.com or shoot a DM to @ptcubed on Instagram.
This is the start of something bigger than a podcast — it’s the official launch of PT³’s next chapter.In this first episode, Dr. Nate Karam, DPT, CSCS shares the raw backstory behind PT³: from life as a baseball player sidelined by injury… to battling depression, autoimmune struggles, and losing his hair… to rebuilding everything through strength training, rehab, nutrition, and mindset.Now a licensed physical therapist, certified strength coach, and founder of PT³ — a real-deal LLC based in Florida — Nate breaks down what this show is all about:✅ Evidence-based strength training✅ Pain-free performance strategies✅ Real rehab conversations✅ Interviews with coaches, athletes, and professionals in the trenches✅ Practical, no-fluff education for lifters, athletes, and anyone ready to level upWhether you’re here to move better, train smarter, or just make sense of the chaos in the fitness world — welcome to the PT³ Podcast.🔗 Resources & Coaching → ptcubed.com📲 Follow Nate on IG → @ptcubed📧 Contact → natekaram@ptcubed.com
If you don't know where you are, how could you ever hope to know where you're going? Let's talk about the art of perpetual self-awareness and how we implement it in our lives to keep our ship sailing on course.
On this episode we will introduce the topic of passions and emotions and how we can can rule the kingdom that is our mind. How do we prevent chaos and disorder? How to we ensure that we respond appropriately to externals and not allow our emotions to get the best of us? How do we utilize our passions to the greatest extent possible and draw the connections needed to derive passion in the places where it is missing in our lives? Come along with me as I attempt to answer some of these questions for myself with the help of one of my favorite reading materials (The Daily Stoic by Ryan Holiday).
On this episode we will further discuss topics of clarity with one of my best friends, Sia Aleem! We met during the beginning of our undergrad experience at the University of Florida and created an organization together revolving around mindset and offering help to our peers with collaborative life coaching and motivational therapy, so I am very excited to have her on this new project with me. Sia is a very valuable and inspiring person in my life who I feel embodies these values of clarity and peace of mind that we have been discussing on previous episodes, so I hope that our discussion provides lots of insight and tools to finding your own clarity and peace of mind!
Welcome to Season 1 of my mainline content for the year! The theme over the next 16 weeks will be Perception, and this episode will specifically focus on the pursuit of clarity. How do we find peace of mind and live happily even under what we perceive to be negative circumstances? Let's explore strategies together to ensure that we have the tools to patch up any potential leak in our mindset!
Pain brings on a great deal of suffering, but suffering is necessary for growth. If you want your mind to be strong and adaptable to any situation, you must know pain and learn to use it to your advantage. Let's talk about how to extract positive lessons out of negative experiences, and use these lessons to clear your lens and see your future self more clearly.









