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Dhru Purohit Show

Author: Dhru Purohit

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Hi, I'm Dhru (like Drew), and every week, I interview the top experts in health, medicine, and mindset to provide you with in-depth, step-by-step protocols to take your health to the next level.

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This episode is brought to you by Our Place, Bon Charge, Cozy Earth, and Maui Nui. We tend to think of vision as an eye issue. But it’s really a brain issue. Nearly half the brain is involved in processing visual information, which means the way we use our eyes can shape our focus, energy, and cognitive performance more than most people realize. Today on The Dhru Purohit Show, Dhru sits down with neuro-optometrist Dr. Bryce Appelbaum to explore why our vision is about far more than eyesight, and how the way we use our eyes every day can profoundly shape brain function, focus, and overall well-being. Dr. Appelbaum explains how modern habits, especially constant screen exposure, are quietly straining our visual system and nervous system. He shares practical strategies to reduce daily eye stress, exercises that can strengthen your visual system and improve attention, and the role of peripheral awareness, movement, and sports in training the eye-brain connection. Dr. Appelbaum also debunks common myths about dyslexia and reading challenges, discusses blue light and screen overload, and breaks down his approach to building visual resilience in a digital world.  Dr. Bryce Appelbaum is a neuro-optometrist and the founder and CEO of MyVisionFirst, a leading practice specializing in functional vision care for all ages. He is known for his work optimizing the eye-brain connection through Vision Performance Training, helping patients recover from concussion-related vision issues, improve visual performance, and build resilience in today’s screen-heavy world. In this episode, Dhru and Dr. Appelbaum dive into: (0:00) Intro (00:47) The powerful neurological link between your eyes and brain (03:38) The modern habits quietly damaging our vision (05:03) Simple ways to reduce daily eye strain (09:26) The long-term consequences of neglecting vision health (14:13) How visual overload leads to brain fog and burnout (19:24) Vision exercises you can do anywhere and why peripheral vision matters (29:43) Dr. Appelbaum’s journey overcoming his own vision challenges (34:14) The truth about dyslexia and reading struggles (45:02) Protecting your eyes in a screen-dominated world (57:08) The surprising power of “eye push-ups” (1:03:06) The best sports for training your eyes and brain (1:07:14) Do reading glasses actually help? (1:10:22) Supplements that support eye health (1:21:56) Why reading makes some people sleepy (1:33:36) Light sensitivity and night driving issues explained (1:36:05) What parents should know about kids’ eye development (1:38:03) Where to find Dr. Appelbaum’s work Also mentioned in this episode: Take the free online vision assessment  Try ScreenFit for Free Free Guide: 5 Steps to Better Vision  Learn more about ScreenFit $200 off ScreenFit™ using code DHRU at screenfit.com/enroll 10% off Digital Performance Lenses using code DHRU The Cancer & Dementia Link Nobody Warned You About with Dr. Satchin Panda LED lighting Undermines Human Visual Performance  The Brain Training That Actually Lowered Dementia Risk Over 20 Years For more on Dr. Appelbaum, follow him on Facebook, Instagram, TikTok, LinkedIn, YouTube, or visit his Website. This episode is brought to you by Our Place, Bon Charge, Cozy Earth, and Maui Nui. Reduce your toxic load by upgrading your cookware! Go to fromourplace.com today and use promo code DHRU to save 40% off from March 23rd through April 12th. Right now, Bon Charge is offering my community 15% off their Red Light Cap. Just go to boncharge.com/dhru and use code DHRU to save 15%. Right now, get 20% off your Cozy Earth sheets and sleepwear. Just head over to cozyearth.com/dhru and use code DHRUP. Right now, Maui Nui Venison is offering my listeners a FREE 12-pack of venison jerky sticks with your first order of $79 or more! Just go to mauinuivenison.com/dhru to secure your access now, but hurry, supply is limited! Sign up for Dhru’s Try This Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices
This episode is brought to you by Puori, One Skin, Rho, and Momentous. Most people trying to lose belly fat are focused on the wrong things. They’re chasing trends, stacking tactics, and putting energy into strategies that barely move the needle, while the biggest drivers of visceral fat often go overlooked. Today on The Dhru Purohit Show, Dhru sits down with fitness expert and Mind Pump co-founder, Sal Di Stefano, to break down what actually matters when it comes to visceral fat. Using a tier-ranking framework, Sal categorizes the biggest contributors to fat gain and the most effective strategies for reducing it. He shares why visceral fat is more dangerous than most people realize, unpacks the real role of hormones like cortisol, testosterone, and estrogen, and clears up the confusion around menopause, hormone replacement therapy, and fat loss. Sal also ranks the impact of sleep, alcohol, ultra-processed foods, and stress, while breaking down the highest-leverage habits for fat loss.  Sal Di Stefano began his fitness journey at just 18, quickly rising to prominence as a trainer and opening some of the largest big-box gyms in the California Bay Area. By 24, he launched a wellness-focused fitness studio that combined expertise in hormones, nutrition, gut health, and fitness training. It was during this time that Sal developed his unique, behavior-focused approach to achieving lasting health and fitness success. Today, Sal is a highly sought-after expert known for his practical, easy-to-apply insights. As co-host of the Mind Pump Podcast, the world’s top fitness and health podcast, he’s appeared on hundreds of leading shows and frequently speaks at events for trainers and health practitioners. In this episode, Dhru and Sal dive into: (0:00) Introduction (1:27) The Hidden Fat You Can’t See and Why It’s Dangerous (4:36) Why Menopause Weight Gain Isn’t What You Think (8:57) Can Hormone Therapy Actually Help You Lose Weight? (17:24) The Truth About Testosterone and Belly Fat (21:42) The Stress Hormone Quietly Driving Belly Fat (27:57) The Impact of HRT in Women (32:36) The Sleep Mistakes Wrecking Your Health (39:32) The Fat-Burning Power of Heavy Lifting (41:40) The Most Underrated Exercise for Weight Loss (48:17) Do You Have to Cut Alcohol? (55:52) GLP-1s Explained: Who Should Use Them and Who Shouldn’t (1:07:36) The Real Problem With Ultra-Processed Foods (1:14:45) Fiber and the Gut Connection You’re Missing (1:22:31) Creatine Myths That Need to Die (1:26:46) Sprinting: Game-Changer or Overhyped? (1:29:41) The Mindset Shift That Changes Your Health and Your Life (1:39:26) How Modern Life Is Quietly Making Us Unhealthy (1:43:00) How to Find Truth in a World Full of Health Noise Also mentioned in this episode: Study on Changes in body composition and weight during the menopause transition  Try This Newsletter on Stress and Cortisol  The 4 Big Causes Of Visceral Belly Fat & How To Burn It ASAP Dr. Vinay Prasad: What is the truth about alcohol consumption For more on Sal and Mind Pump, follow them on Facebook, X/Twitter, Instagram, Apple Podcasts, TikTok, YouTube, and their Website. This episode is brought to you by Puori, One Skin, Rho, and Momentous. Quality protein matters. Get 32% off Puori Grass-Fed Whey Protein and a free shaker when you start a subscription at puori.com/DHRU and use code DHRU at checkout.  Right now, One Skin is offering my community 15% off; just go to oneskin.co and use the coupon code DHRU to save 15% and give your skin the scientifically proven, gentle care it deserves. Try Rho Nutrition today and experience the difference of Liposomal Technology. Use code DHRU for 20% OFF everything at rhonutrition.com/discount/dhru. Right now, Momentous is offering our listeners up to 35% off their first order with promo code DHRU. Head to ⁠livemomentous.com⁠ and use code DHRU for 35% off your first subscription. Sign up for Dhru’s Try This Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices
This episode is brought to you by Cozy Earth, BiOptimizers,  Maui Nui, and One Skin.  We’ve been told that cognitive decline is just a normal part of aging. But what if the real story has less to do with age and more to do with how we’re living? Your brain is constantly adapting to the signals you give it, and those signals may matter far more than you think. Today on The Dhru Purohit Show, Dhru sits down with neuroscientist and performance expert Dr. Tommy Wood to challenge the idea that cognitive decline is inevitable and reveal how our modern lifestyle may be quietly reshaping our brain health. Dr. Wood explains why dementia risk is often a mismatch problem, breaks down the Movement Funnel and the three types of exercise that stimulate different brain networks, and shares his “3 S’s” framework for building long-term resilience. He also unpacks the science behind high-intensity training, purpose and social connection, brain training, stress, creatine, and what truly separates superagers from everyone else. Dr. Tommy Wood is an Associate Professor of Pediatrics and Neuroscience at the University of Washington, where his research focuses on brain health across the lifespan, from newborn brain injury to adult traumatic brain injury and long-term cognitive decline. He earned an undergraduate degree in biochemistry from the University of Cambridge, a medical degree from the University of Oxford, and a PhD in Physiology and Neuroscience from the University of Oslo. He has consulted with elite athletes, including multiple Formula 1 drivers, and serves as Director and Treasurer of the British Society of Lifestyle Medicine and as Head of Research for the dementia-prevention charity Food for the Brain. In this episode, Dhru and Dr. Wood dive into: (0:00) Intro (2:03) Cognitive decline isn’t a brain issue; it’s a lifestyle mismatch (10:18) The overlooked force that could matter more than any supplement. (15:00) How modern life quietly reshaped our thinking about aging and mortality (18:37) The evolutionary truth your body and brain still expect from you (30:29) The landmark study that changed how scientists view dementia risk (41:06) Why pushing your limits might sharpen your mind faster (44:00) The framework that explains why your workouts may not be enough (50:57) What early childhood movement reveals about lifelong brain resilience (57:30) The three simple levers that could shift your brain’s trajectory (1:18:06) Why brain games are not the full answer to cognitive longevity (1:28:22) How purpose-driven communities seem to outperform biology (1:35:57) The counterintuitive way to think about stress and long-term health (1:41:28) The surprising compound that fuels both muscle and mind (1:46:50) What truly separates superagers from everyone else (1:53:03) The mindset shift that ties everything together Also mentioned in this episode: The Stimulated Mind Brain HQ Creative Experiences and Brain Clocks Study For more on Dr. Wood, follow him on X/Twitter, Instagram, LinkedIn, Apple Podcasts, or visit his Website. This episode is brought to you by Cozy Earth, BiOptimizers, Maui Nui, and One Skin.  Right now, get 20% off your Cozy Earth sheets and sleepwear. Just head over to cozyearth.com/dhru and use code DHRUP. Upgrade your digestion with enzymes! Go to bioptimizers.com/dhru now and enter promo code DHRU to get 15% off any MassZymes order and all BiOptimizers products. Right now, Maui Nui Venison is offering my listeners a limited collection of my favorite cuts and products and a FREE 12-pack of venison jerky sticks with your first order of $79 or more! Just go to mauinuivenison.com/dhru to secure your access now, but hurry, supply is limited! Right now, One Skin is offering my community 15% off; just go to oneskin.co and use the coupon code DHRU to save 15% and give your skin the scientifically proven, gentle care it deserves. Sign up for Dhru’s Try This Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices
This episode is brought to you by Puori, Fatty15, Our Place, and Branch Basics. When it comes to pregnancy, most advice focuses on what to avoid. But what if the real conversation should be about what actively builds your baby’s brain and long-term health? Today on The Dhru Purohit Show, Dhru sits down with Jessie Inchauspé to discuss the four building blocks of pregnancy nutrition. Dhru and Jessie dive into the hidden impact of glucose on your baby’s developing brain, the pregnancy nutrition myths that need to go, and the overlooked nutrient that helps wire memory before birth. They unpack nausea and food aversions, share simple glucose hacks every pregnant mom should know. Jessie also highlights the protein mistake most moms don’t realize they’re making, explains the connection between glucose, inflammation, and the brain cells few people talk about, and breaks down the truth about “eating for two.”   Jessie Inchauspé is on a mission to translate cutting-edge science into simple, practical tools for better physical and mental health. As the founder of the popular @GlucoseGoddess account, she shares life-changing food habits with hundreds of thousands of people. In her bestselling book Glucose Revolution, she uncovers how blood sugar shapes everything from cravings to fertility and offers easy, science-backed hacks to optimize it, without giving up the foods you love. In this episode, Dhru and Jessie dive into:  (0:00) Intro (2:13) The hidden impact of glucose on your baby’s brain (10:00) Pregnancy nutrition myths that need to go (12:10) The overlooked nutrient that helps wire memory (18:18) Nausea and food aversions (19:46) Simple glucose hacks every pregnant mom should know (31:24) The fish debate: what actually matters for baby’s brain (34:43) The protein mistake most moms don’t realize they’re making (39:41) Glucose, inflammation & the brain cells no one talks about (44:30) Dhru opens up about his wife’s pregnancy journey (47:31) Are you really “eating for two”? The calorie truth (53:30) How Jessie feeds her son (and why it matters) (55:20) What Jessie would do differently before getting pregnant (1:00:20) The protein powder Jessie personally uses Also mentioned in this episode: 9 Months That Count Forever  Autism Prevention 5 Days a Week For more on Jessie, follow her on Facebook,  X/Twitter, Instagram, TikTok, YouTube, or visit her Website. This episode is brought to you by Puori, Fatty15, Our Place, and Branch Basics. Quality protein matters. Get 32% off Puori Grass-Fed Whey Protein and a free shaker when you start a subscription at puori.com/DHRU and use code DHRU at checkout.  Fatty15 is offering an additional 15% off its 90-day subscription Starter Kit. Go to fatty15.com/dhru and use code DHRU to replenish your C15 levels for long-term health. Reduce your toxic load by upgrading your cookware! Go to fromourplace.com today and use promo code DHRU at checkout to receive 10% off any order. Right now, Branch Basics is offering 15% off the Premium Starter Kit; just go to branchbasics.com and use the coupon code DHRU. Make 2026 your cleanest, healthiest year yet with Branch Basics! Sign up for Dhru’s Try This Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices
This episode is brought to you by Cozy Earth, LMNT, Maui Nui, and One Skin. When we think about weight loss, it’s usually framed as a matter of willpower. Eat less. Move more. Try harder. But this episode explores an alternative perspective. Dr. Jason Fung argues that obesity isn’t simply about calories, but about hunger, hormones, and what he describes as a biological “fat thermostat” that may be working against you. Today on The Dhru Purohit Show, Dhru sits down with Dr. Jason Fung to unpack his framework for understanding weight gain and fat loss. Dr. Fung explains why he believes calorie restriction often fails, the three types of hunger he describes, and how what he calls “over-hunger” may drive weight gain more than overeating alone. He also breaks down his concept of the “fat thermostat,” metabolic compensation, and what he believes we can learn from other cultures about food environments. He shares his views on GLP-1 drugs, protein needs, and the three “golden rules” he recommends for resetting hunger naturally. Dr. Jason Fung is a Nephrologist, researcher, and bestselling author known for reshaping the conversation around obesity, diabetes, and fasting. His books, The Obesity Code, The Diabetes Code, and The Complete Guide to Fasting, have sold over 1 million copies worldwide and have challenged conventional treatment approaches for type 2 diabetes. He is also the author of The Cancer Code and cofounder of The Fasting Method, a program that helps people lose weight and reverse type 2 diabetes through evidence-based fasting. His work has been featured in CNN, Time, The Atlantic, and Forbes. In this episode, Dhru and Dr. Fung dive into: (0:00) Intro (00:37) The Real Problem Isn’t Overeating. It’s Over-Hunger (5:26) The 3 Types of Hunger (And Which One Is Controlling You) (13:08) Are Some Calories Actually More Fattening Than Others? (17:07) The “Fat Thermostat” That’s Secretly Defending Your Weight (33:51) How Ultra-Processed Foods Hijack Your Hormones (41:46) The “Healthy” Ultra-Processed Foods Hiding in Plain Sight (45:10) What Other Countries Get Right About Food (That We Don’t) (52:00) Who Told Us We Needed to Snack Every 3 Hours? (55:50) Are You Eating Enough Protein?  (1:03:23) GLP-1s: Breakthrough Tool or Temporary Fix? (1:12:34) The 3 Golden Rules That Actually Reset Hunger (1:19:45) Can You Overeat “Healthy” Food?  (1:21:45) Why Mindless Eating Is More Powerful Than You Think (1:29:35) The Hidden Habits That Keep You Hungry (1:37:12) Health Markers That Reveal Your Metabolism Is Struggling (1:45:10) Where to Go Deeper with Dr. Jason Fung Also mentioned in this episode: The Hunger Code: Resetting Your Body's Fat Thermostat in the Age of Ultra-Processed Food Dr. Jason Fung Masterclass  The Biggest Ozempic Mistakes: What to Do After GLP-1 Drugs to Keep the Weight Off for Good with Dr. Holly Wyatt and Dr. James Hill For more on Dr. Fung, follow him on Facebook, X/Twitter, Instagram, YouTube, or visit his Website. This episode is brought to you by Cozy Earth, LMNT, Maui Nui, and One Skin. Right now, get 20% off your Cozy Earth sheets and sleepwear. Just head over to cozyearth.com/dhru and use code DHRUP. Check out LMNT’s new refreshing slim sparkling cans in Pineapple Salt, Lemonade Salt, Black Cherry Salt, and Orange Salt! Right now, LMNT is offering my listeners a free electrolyte sample pack with any purchase. Head over to drinkLMNT.com/dhru today. Right now, Maui Nui Venison is offering my listeners a limited collection of my favorite cuts and products and a FREE 12-pack of venison jerky sticks with your first order of $79 or more! Just go to mauinuivenison.com/dhru to secure your access now, but hurry, supply is limited! Right now, One Skin is offering my community 15% off; just go to oneskin.co and use the coupon code DHRU to save 15% and give your skin the scientifically proven, gentle care it deserves. Sign up for Dhru’s Try This Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices
This episode is brought to you by Bon Charge, BiOptimizers, Momentous, and Branch Basics.   When we think about cognitive decline, it’s often framed as something inevitable, something that just happens with age. But this episode challenges that narrative, revealing that brain health is far more dynamic, responsive, and within our control than we’ve been led to believe. Today on The Dhru Purohit Show, Dhru sits down with Dr. Majid Fotuhi to unpack what it really takes to protect, strengthen, and even improve your brain as you age. Dr. Fotuhi explains why cognitive decline exists on a spectrum, how lifestyle choices can slow or prevent it, and what the latest research says about reversing early Alzheimer’s. He shares powerful patient stories, breaks down the surprising link between hearing loss and memory issues, and outlines his Five Pillars of Brain Health. Dr. Fotuhi also dives into Tau PET scans, cutting-edge brain training strategies, and why taking action now may be the single most important decision you make for your future cognitive health. Dr. Majid Fotuhi is a neurologist specializing in memory, concussion, and successful aging. With over 30 years of teaching, clinical practice, and neuroscience research at Harvard Medical School and Johns Hopkins, he has developed a multidisciplinary program to help people of all ages improve memory and attention. The results of his program have been published in numerous scientific journals and in his three books. Passionate about public education on brain health, Dr. Fotuhi also teaches in the Department of Psychological and Brain Sciences at George Washington University and at Harvard Medical School. In this episode, Dhru and Dr. Fotuhi dive into: (0:00) Intro (00:39) Can you slow cognitive decline (2:30) The overlooked daily habits that make or break your brain (6:56) Surprising patient results (17:50) Understanding the spectrum of cognitive decline (22:36) The surprising link between hearing loss and memory loss (30:54) How research on reversing Alzheimer’s has evolved (37:27) Why waiting for symptoms could be your biggest mistake (40:25) The Five Pillars of Brain Health (53:12) The most powerful brain reset you’re probably undervaluing (56:29) Brain-friendly nutrition: what to embrace and what to avoid (1:07:00) Purpose, mindset, and cortisol: the hidden brain chemistry connection (1:17:23) Tau PET scans explained: what they reveal about your brain (1:29:24) Can you train your brain like a muscle? (1:35:27) Inside the 12-week brain training protocol (1:42:42) Dr. Fotuhi’s most important brain health advice Also mentioned in this episode: The Invincible Brain: The Clinically Proven Plan to Age-Proof Your Brain and Stay Sharp for Life Is Eating Fish Safe? A Lot Safer Than Not Eating Fish! Seatopia Fish For more on Dr. Fotuhi, follow him on Facebook, X/Twitter, Instagram, TikTok, LinkedIn, YouTube, or visit his Website. This episode is brought to you by Bon Charge, BiOptimizers, Momentous, and Branch Basics. Right now, Bon Charge is offering my community 15% off their Red Light Cap. Just go to boncharge.com/dhru and use code DHRU to save 15%. Upgrade your digestion with enzymes! Go to bioptimizers.com/dhru now and enter promo code DHRU to get 15% off any MassZymes order and all BiOptimizers products. Right now, Momentous is offering our listeners up to 35% off their first order with promo code DHRU. Head to livemomentous.com and use code DHRU for 35% off your first subscription. Right now, Branch Basics is offering 15% off the Premium Starter Kit; just go to branchbasics.com and use the coupon code DHRU. Make 2026 your cleanest, healthiest year.  Sign up for Dhru’s Try This Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices
This episode is brought to you by Puori, Cozy Earth, Fatty15, and Birch Living. Circadian rhythm is one of the most overlooked drivers of long-term health. It influences when we sleep, how we metabolize food, how our brain repairs itself, and even how our immune system functions. When this internal clock falls out of sync, the effects ripple through every system in the body. Today on The Dhru Purohit Show, Dhru sits down with circadian biology expert Dr. Satchin Panda to explore the four pillars of circadian health and how losing alignment can contribute to cognitive decline and Alzheimer’s disease. Dr. Panda shares key strategies to reduce your risk and breaks down the science behind why protecting your master clock is critical for preventing chronic disease. He also explains the importance of time-restricted eating, how timing influences the effectiveness of medications and cancer immunotherapy, and the role exercise plays in detoxification.  Dr. Satchin Panda is a world-renowned pioneer in circadian biology and a Professor at the Salk Institute for Biological Studies, where he holds the Rita and Richard Atkinson Chair. Recently named a semifinalist in the XPRIZE Healthspan competition, Dr. Panda leads "Team Circadian" in groundbreaking research to reverse biological aging through rhythmic optimization. His discovery of the blue-light sensitive protein melanopsin and his extensive research on time-restricted eating have reshaped global health guidelines, leading to featured presentations at premier international forums including the American Diabetes Association and the professional diabetes societies of Europe and Australia. In this episode, Dhru and Dr. Panda dive into: (0:00) Intro (00:59) The Circadian–Alzheimer’s Connection (3:00) Why Light Controls Your Health (26:36) Sleep as Brain Defense  (34:01) Inside Your Master Clock  (38:17) Why Meal Timing Matters  (49:33) Time-Restricted Eating Explained  (57:12) Timing Your Medications  (1:01:27) Circadian Biology & Cancer Treatment  (1:09:25) Exercise as Cancer Insurance  (1:16:01) What Exercise Does at the Cellular Level  (1:26:23) Minimum Effective Dose of Movement  (1:57:47) The Circadian Challenge  (2:06:21) Circadian Rhythm as Your Operating System  (2:11:20) Final Takeaways  Also mentioned in this episode: OnTime Health App  Human Performance Alliance  For more on Dr. Satchin Panda, follow him on X/Twitter, Instagram, Ontime Health’s Instagram, YouTube, LinkedIn, or visit his Website. This episode is brought to you by Puori, Cozy Earth, Fatty15, and Birch Living. Quality protein matters. Get 32% off Puori Grass-Fed Whey Protein and a free shaker when you start a subscription at puori.com/DHRU and use code DHRU at checkout.  Right now, get 20% off your Cozy Earth sheets and sleepwear. Just head over to cozyearth.com/dhru and use code DHRUP. Fatty15 is offering an additional 15% off its 90-day subscription Starter Kit. Go to fatty15.com/dhru and use code DHRU to replenish your C15 levels for long-term health. Birch is exclusively offering my community 27% off their Birch Living mattress—just head to birchliving.com/dhru today. Sign up for Dhru’s Try This Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices
This episode is brought to you by BiOptimizers, LMNT, Maui Nui, and Branch Basics.  When we think about fitness and health, walking is often seen as “too easy” to matter. But this episode challenges that assumption, revealing how walking with weight taps into a deeply human ability that builds strength, resilience, and long-term health in ways most modern workouts miss. Today on The Dhru Purohit Show, Dhru sits down with Michael Easter to explore walking with weight, a forgotten human practice that quietly shaped our bodies, minds, and resilience, and what happens when modern life removes it. Michael traces the evolutionary roots of carrying and movement, explains why many popular fitness approaches fall short, and reveals how this deceptively simple practice can transform strength, endurance, metabolic health, and mental clarity. Michael challenges our obsession with comfort, unpacks the science behind walking with weight, and shares practical insights on how small, intentional discomfort can help us live stronger, more capable, and more resilient lives in a hyper-convenient world. Michael Easter is a New York Times bestselling author who travels the world uncovering practical, science-backed ideas for living healthier, happier, and more remarkable lives. His reporting has taken him from war zones to the Arctic to the Bolivian jungle, where he’s interviewed thousands of experts, from Nobel laureates to elite athletes, and analyzed cutting-edge research. He shares these insights through his bestselling books The Comfort Crisis and Scarcity Brain, as well as his newsletter Two Percent. His work is used by professional sports teams, Fortune 500 companies, and elite military units, and has helped millions rethink health, performance, and modern life. In this episode, Dhru and Michael dive into:  (0:00) Intro (00:37) Why humans were designed to walk and what we’ve forgotten(04:28) What happens when you add weight to your walks(12:37) Running, carrying, and the hidden blueprint of human movement(20:00) The Tarahumara tribe and what modern fitness gets wrong(26:11) The real idea behind “Walk With Weight”(31:29) Why choosing comfort may be costing you health and resilience(34:24) Simple, real-world ways to start walking with weight(38:24) How weighted walking quietly increases calorie burn(40:04) What the research actually says about walking with weight(47:27) The easiest way to begin walking with weight(56:12) The overlooked science behind weighted walking benefits(1:02:00) The surprising mental and emotional gains from walking with weight(1:09:39) How Michael suggests introducing this practice to others(1:12:07) Where to explore more of Michael’s work Also mentioned in this episode: Walk with Weight: The Definitive Guide to Rucking Walkfully Site For more on Michael, follow him on Facebook, X/Twitter, Instagram, Threads, Substack, or visit his Website. This episode is brought to you by BiOptimizers, LMNT, Maui Nui, and Branch Basics.  Upgrade your digestion with enzymes! Go to bioptimizers.com/dhru now and enter promo code DHRU to get 15% off any MassZymes order and all BiOptimizers products during their Valentine's Day deal. Right now, LMNT is offering my listeners a free sample pack with any purchase. Head over to drinkLMNT.com/dhru today. Right now, Maui Nui Venison is offering my listeners exclusive access to their brand-new Always Summer Sausage, the cleanest, most nutrient-dense lunch meat you’ll find. Just go to mauinuivenison.com/DHRU to get yours today.  Right now, Branch Basics is offering 15% off the Premium Starter Kit; just go to branchbasics.com and use the coupon code DHRU. Make 2026 your cleanest, healthiest year yet with Branch Basics! Sign up for Dhru’s Try This Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices
This episode is brought to you by Bon Charge, Momentous, Cozy Earth, and Our Place. When we think about aging, menopause is often framed as something to endure or “get through.” But this episode challenges that narrative, revealing menopause as a powerful biological and neurological transition that can unlock greater clarity, resilience, and purpose.  Today on The Dhru Purohit Show, Dhru sits down with Dr. Mindy Pelz to reframe menopause as a powerful biological, psychological, and cultural initiation, not a decline. Dr. Pelz traces the mythology and history that shaped how we view menopause, explains what modern science gets right (and wrong), and unpacks why intense emotions, brain changes, and identity shifts are not signs of dysfunction but signals of transformation. She also dives into practical guidance around nutrition, glucose balance, hormones, genetics, and daily habits that support women in this stage of life, while offering insight into how men can better support the women they love.    Dr. Mindy Pelz is a New York Times bestselling author, visionary educator, and trailblazer in women’s health and hormone science with over two decades of experience building a global movement that helps women understand and harness the power of their bodies at every stage of life. Her new book Age Like a Girl blends cutting-edge science with personal insight to show how fasting, nutrition, and lifestyle shifts can balance hormones, boost energy, and turn midlife’s neurochemical changes into a launchpad for purpose and reinvention. With a Doctorate of Chiropractic and a background in functional nutrition, she brings both rigor and heart to her work championing a bold message: aging isn’t a decline; it’s an evolution, and now is the time for women to get stronger, clearer, and more connected to who they truly are. In this episode, Dhru and Dr. Mindy dive into: (0:00) Intro (1:04) The ancient meaning of menopause and how we lost it (3:08) The forgotten roadmap of a woman’s life (6:42) How menopause became medicalized and what we lost along the way (12:28) What today’s menopause conversation gets wrong (19:19) Why emotional intensity is a message, not a malfunction (31:17) The nervous-system breaking point that changed everything for Dr. Mindy (40:07) Why the world needs elder women more than ever (45:57) The truths women must know about this stage of life (51:02) Why menopause requires a totally different way of eating (55:39) The simple daily rituals guiding Dr. Mindy’s current season (59:51) The genetic signals most women never hear about (1:10:01) Why doing less might be the ultimate health upgrade (1:23:08) How men can better understand and support the women they love (1:39:29) Rewriting menopause for the next generation Also mentioned in this episode: Age Like a Girl, Dr. Mindy Pelz’s new book  Chris Kresser Article on HbA1C Dr. Ben Bikman’s Concerns About HbA1C For more on Dr. Mindy, follow her on Instagram, Facebook, TikTok, YouTube, Apple Podcasts, Spotify, Amazon Music, LinkedIn, or her Website. This episode is brought to you by Bon Charge, Momentous, Cozy Earth, and Our Place. Right now, Bon Charge is offering my community 15% off their Red Light Cap. Just go to boncharge.com/dhru and use code DHRU to save 15%. Right now, Momentous is offering our listeners up to 35% off their first order with promo code DHRU. Head to livemomentous.com and use code DHRU for 35% off your first subscription. Right now, get 20% off your Cozy Earth sheets and sleepwear. Just head over to cozyearth.com/dhru and use code DHRUP. Reduce your toxic load by upgrading your cookware! Go to fromourplace.com today and use promo code DHRU at checkout to receive 10% off any order. Sign up for Dhru’s Try This Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices
This episode is brought to you by Maui Nui, One Skin, Branch Basics, and BetterWild. When we think about longevity, immune health, or aging well, sex is rarely part of the conversation. But this episode challenges that blind spot, revealing why sexual connection and pleasure are fundamental to health, resilience, and how fully we experience life. Today on The Dhru Purohit Show, Dhru sits down with sex and relationships expert Dr. Nicole McNichols to unpack why sexual pleasure is far more than a “nice-to-have”; it’s a foundational pillar of health, connection, and long-term fulfillment. Dr. McNichols explores how sexual satisfaction influences healthy aging, sleep quality, immune function, and relationship resilience, while dismantling some of the most common myths around desire, mystery, and attraction. This conversation reframes sex as a skill you can cultivate, not a spark you either have or lose, and offers practical insights for couples who want deeper connection, better communication, and intimacy that evolves. Dr. Nicole McNichols is a renowned professor of human sexuality, author, and speaker with over 20 years of experience bridging science and real-world application to help people better understand sexuality, relationships, and pleasure. Her course, The Diversity of Human Sexuality, is the most popular in the University of Washington's history, enrolling more than 4,000 students annually. She is the author of the upcoming book You Could Be Having Better Sex. Her work has been featured in Psychology Today, The Seattle Times, and Harvard Business Review, and she is the coauthor of Human Sexuality in a Diverse Society and a TEDx speaker.  In this episode, Dhru and Dr. McNichols dive into:  (0:00) Intro (00:39) Why pleasure is essential for health (02:07) The link between sexual satisfaction and longevity (14:09) How sexual connection drives life satisfaction (22:19) How male and female brains experience desire differently (28:23) The sex, sleep, immunity connection (38:40) Why planned intimacy works better than spontaneity (41:38) Why desire loss doesn’t mean love loss (54:17) Creating intimacy space by reducing friction (1:08:00) Dr. McNichols’ path to becoming a sex educator (1:21:10) Self-actualization in marriage (1:25:50) Navigating mismatched desire without resentment (1:34:05) Why sex matters in long-term relationships (1:40:27) What happens when sexual wellness is deprioritized (1:42:34) Final takeaways Also mentioned in this episode: You Could Be Having Better Sex: The Definitive Guide to a Happier, Healthier, and Hotter Sex Life  For more on Dr. McNichols, follow her on X/Twitter, Instagram, TikTok, LinkedIn, or visit her Website. This episode is brought to you by Maui Nui, One Skin, Branch Basics, and Betterwild. Right now, Maui Nui Venison is offering my listeners exclusive access to their brand-new Always Summer Sausage, the cleanest, most nutrient-dense lunch meat you’ll find. Just go to mauinuivenison.com/DHRU to get yours today.  Right now, One Skin is offering my community 15% off; just go to oneskin.co and use the coupon code DHRU to save 15% and give your skin the scientifically proven, gentle care it deserves. Right now, Branch Basics is offering 15% off the Premium Starter Kit; just go to branchbasics.com and use the coupon code DHRU. Make 2026 your cleanest, healthiest year yet with Branch Basics! Right now, BetterWild is offering my listeners up to 40% off at BetterWild.com/DHRU. Support your dog’s digestion and allergy defense system today.  Sign up for Dhru’s Try This Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices
This episode is brought to you by Bon Charge, BiOptimizers, Our Place, and Cozy Earth. True progress often isn’t blocked by a lack of effort, but by hidden traps in how we think, strive, and apply our energy. Many of us push harder, stay busier, and demand more from ourselves, only to feel burned out, stuck, or misaligned. Working harder isn’t always the answer, and today’s guest shows us why. Today on The Dhru Purohit Show, Dhru sits down with psychologist Dr. Diana Hill to explore how the way we use our energy, not just how hard we try, shapes our health, relationships, and sense of purpose. Dr. Hill unpacks why so many high-achievers feel burned out, stuck, or quietly dissatisfied despite doing “all the right things,” and reveals the hidden traps that keep us spinning our wheels, from misusing our strengths to chasing goals that don’t align with our values. She also introduces the idea of wise effort versus forcing change through pressure and self-criticism. This conversation offers a powerful reframe for anyone who feels overextended or misdirected, showing how psychological flexibility and values-based choices can restore vitality, clarity, and a deeper sense of alignment in everyday life. Dr. Diana Hill is a psychologist and international trainer specializing in Acceptance and Commitment Therapy (ACT). She helps individuals and organizations build psychological flexibility using science-backed, compassion-driven tools. Diana is the author of four books, including Wise Effort, hosts the Wise Effort podcast, and has been featured in NPR, The Wall Street Journal, Psychology Today, and more—known for making complex psychology practical, clear, and deeply usable. In this episode, Dhru and Dr. Hill dive into:  (0:00) Intro (1:37) When effort turns against you and pushing harder makes things worse (3:47) The quiet reason resolutions fail and what your intuition already knows (10:55) The hidden story we were taught about growth and why it’s misleading (19:02) How your energy gets drained without you ever noticing (25:46) The perspective shift that changes how you meet challenges and yourself (30:52) Dr. Hill’s wake-up moment and the unseen cost of trying too hard (43:30) Why reaching the goal still leaves something missing (48:07) What avoiding discomfort is actually costing you (58:46) Discovering your “genius energy” and what it’s meant for (1:17:16) The self-limiting stories that feel true but quietly hold you back (1:25:40) The subtle trap of chasing goals instead of living your values (1:28:17) Dr. Hill’s closing insight on trusting your inner compass Also mentioned in this episode: Wise Effort: How to Focus Your Genius Energy on What Matters Most For more on Dr. Hill, follow her on Instagram, Facebook, LinkedIn, YouTube, Apple Podcasts, Insight Timer, or visit her Website. This episode is brought to you by Bon Charge, BiOptimizers, Our Place, and Cozy Earth. Right now, Bon Charge is offering my community 15% off. Just go to boncharge.com/dhru and use code DHRU to save 15%. Go to bioptimizers.com/dhru now and enter promo code DHRU to get 26% off select products and bundles during their New Year New You sale. Reduce your toxic load by upgrading your cookware! Go to fromourplace.com today and use promo code DHRU at checkout to receive 10% off any order. Right now, get 20% off your Cozy Earth sheets and sleepwear. Just head over to cozyearth.com/dhru and use code DHRUP. Sign up for Dhru’s Try This Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices
This episode is brought to you by LMNT, Maui Nui, Momentous, and One Skin. Muscle health shapes far more than our appearance, impacting metabolism, energy, resilience, and aging, yet most of us were never taught how to build it or adopt the mindset to protect it for life. Today’s episode explores why shifting toward a muscle-centric approach isn’t intuitive in modern culture, and how learning to train both the body and the mind may be one of the most important upgrades for long-term health. Today on The Dhru Purohit Show, Dhru sits down with Dr. Gabrielle Lyon to explore why muscle is far more than a fitness goal; it’s a central driver of longevity, metabolic health, and resilience. Together, they unpack the muscle-centric paradigm and how building strength shapes not only the body but also the mindset, emotional regulation, and identity. Dr. Lyon explains the power of neutrality and discernment in unhijacking reactive thought patterns, shares practical tools for moving from complaint to action, and breaks down how clarity of purpose fuels lasting change. This episode reframes health as a responsibility, not a luxury, and offers a roadmap for building strength that carries through every aspect of life. Dr. Gabrielle Lyon is a Washington University fellowship-trained physician in nutritional science and geriatrics, board-certified in family medicine, and the founder of the Institute for Muscle-Centric Medicine. She runs a private practice serving leaders, innovators, mavericks, and executives across multiple fields, while also working closely with special operations military personnel, all to shift medicine from an obesity-focused model to a muscle-centric paradigm grounded in high scientific integrity.  She is the bestselling author of Forever Strong and the upcoming Forever Strong Playbook.  In this episode, Dhru and Dr. Lyon dive into:  (0:00) Intro (1:00) The muscle mandate: why strength is no longer optional for long-term health (2:15) A mindset shift: how culture quietly reshapes our relationship with strength (15:08) The missing skill in a reactive, overstimulated world (18:57) Practicing neutrality: how to observe thoughts without being hijacked by them (32:20) Simple tools to break autopilot in real time (38:49) Your “why”: the hidden driver behind consistency and real change (52:44) How to interrupt the complaining loop before it drains your energy (57:14) Capacity versus challenge and determining where growth happens (1:02:38) Moving past stagnation and identifying areas for growth Also mentioned in this episode: The Forever Strong PLAYBOOK: Rewrite Your Future in Six Weeks Forever Strong For more on Dr. Lyon, follow her on Instagram, Facebook, X/Twitter, TikTok, YouTube, Apple Podcasts, or visit her Website. This episode is brought to you by LMNT, Maui Nui, Momentous, and One Skin.   Right now, LMNT is offering my listeners a free sample pack with any purchase. Head over to drinkLMNT.com/dhru today. Right now, Maui Nui Venison is offering my listeners exclusive access to their brand-new Always Summer Sausage, the cleanest, most nutrient-dense lunch meat you’ll find. Just go to mauinuivenison.com/DHRU to get yours today.  Optimize your energy and mental clarity with the purest form of creatine, made by and used by the best. Head to livemomentous.com and use code DHRU for 35% off your first subscription. Right now, One Skin is offering my community 15% off; just go to oneskin.co and use the coupon code DHRU to save 15% and give your skin the scientifically proven, gentle care it deserves. Sign up for Dhru’s Try This Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices
This episode is brought to you by Puori, Hollow Socks, Fatty15, and Branch Basics. Light shapes far more than our sleep; it influences our metabolism, hormones, energy, and long-term health. Yet modern life has quietly flipped our light environment upside down: too little sunlight during the day and too much artificial light at night. Today’s episode explores why that mismatch may be costing us far more than we realize. Today on The Dhru Purohit Show, Dhru sits down with Jonathan Jarecki to explore the critical role of sunlight, especially infrared light, in health and longevity. They break down key studies on sun exposure, including its impact on melatonin production, metabolic health, and overall well-being. Jonathan also shares his 2026 Light Challenge (with beginner and advanced levels) and practical strategies for getting more natural light during the day, reducing artificial light at night, and understanding the health risks of inadequate sun exposure. This episode is a powerful reminder that light isn’t just a backdrop to our lives, it’s a biological signal that shapes long-term health. Jonathan Jarecki is a pre-medical student, studying Biology and Neuroscience. He’s passionate about preventive medicine, evidence-based wellness, and translating cutting-edge research into practical tools for everyday life, exploring how light, water, and bioelectromagnetism shape health, performance, and longevity. In this episode, Dhru and Jonathan dive into:  (0:00) Intro (1:05) The importance of light and sun exposure on lifespan (11:20) ICU infrared LED light study (24:06) The connection between the sun, mitochondria, and melatonin (34:40) The 2026 Beginner Light Challenge (38:56) The role of sunlight exposure in metabolic health (56:12) A lunch-break habit that can reprogram your biology (1:00:23) Why evening sunlight matters more than you think (1:06:33) The phone settings that protect your brain after dark (1:09:27) How much light do you actually need each day? (1:11:20) The Advanced Light Challenge for next-level health (1:14:46) Sunbathing: misunderstood, demonized, and powerful (1:23:32) Why overhead lights at night are a hidden stressor (1:30:46) Jonathan’s story and journey into studying light (1:35:27) Final thoughts and key takeaways Also mentioned in this episode: 2026 Light Challenge Research links Strainless Lighting Amber Vintage Incandescent Light Bulbs Healthlighting How to turn on night shift mode on your phone Try This: Fred Kummerow Want to Maintain Youthful Skin At Any Age? Top Dermatologist and Skin Cancer Expert Shares His Favorite Skin Tips and Tools For more on Jonathan, follow him on Instagram, Whole Health’s Instagram, LinkedIn, Threads, YouTube, Apple Podcasts, Spotify, or visit his Website. This episode is brought to you by Puori, Hollow Socks, Fatty15, and Branch Basics. Quality protein matters. Get 32% off Puori Grass-Fed Whey Protein and a free shaker when you start a subscription at puori.com/DHRU and use code DHRU at checkout.  For a limited time, Hollow Socks is offering my community a Buy 3, Get 3 Free Sale. Head to HollowSocks.com for up to 50% off your order. Fatty15 is offering an additional 15% off its 90-day subscription Starter Kit. Go to fatty15.com/dhru and use code DHRU to replenish your C15 levels for long-term health. Right now, Branch Basics is offering 15% off the Premium Starter Kit; just go to branchbasics.com and use the coupon code DHRU. Make 2025 your cleanest, healthiest year yet with Branch Basics! Sign up for Dhru’s Try This Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices
This episode is brought to you by Bon Charge, One Skin, Maui Nui, and Cozy Earth. When we think about chronic disease, we don’t always consider the role of emotions. Yet emotional patterns can quietly drive chronic inflammation, which underlies many of today’s most common conditions. Today’s guest shares powerful stories from patients with unexpected diagnoses, revealing how core life habits and major life events often precede, and contribute to, the development of disease. Today on The Dhru Purohit Show, Dhru sits down with Dr. Ronesh Sinha to explore the often-overlooked emotional factors behind chronic illness, even in people who appear to be doing everything “right” for their health. Dr. Sinha introduces the concept of surprise diseases, explains how emotional patterns shape physical outcomes, and unpacks ideas like “shamily” and emotional immunity. He also shares practical ways to build emotional awareness, why introspection matters, and how open, honest conversations within families can be a powerful tool for long-term health. Dr. Ronesh Sinha is an internal medicine physician and author of The South Asian Health Solution, who runs a Silicon Valley lifestyle clinic focused on reversing insulin resistance. He serves as Chief Medical Officer for the Silicon Valley Employer Forum, advising major tech companies on health benefits. His work has been featured in Fortune Magazine and the Los Angeles Times, and he hosts the Meta Health Podcast. In this episode, Dhru and Dr. Sinha dive into:  (0:00) Intro (1:05) The invisible risk shaping our metabolic health (5:47) How emotional suppression fuels “surprise” diseases (11:55) Shamily: emotional stability, patterns, and family dynamics (19:16) What stress really does to the immune system (33:17) Emotional immunity: the missing layer of health (39:32) The hidden meaning behind head flicks and body signals (47:17) Why emotional suppression is like an Instant Pot (54:56) How subvocalization quietly impacts your health (1:00:23) Recognizing emotional patterns tied to your personality (1:10:05) How our thoughts shape connection and belonging (1:12:23) Simple introspection and relaxation tools that work (1:16:42) What happens when vulnerability enters family dynamics (1:22:57) How emotional authenticity improves well-being Also mentioned in this episode: Try This: 7 Things I’m Doing To Keep My Parents Healthy As They Get Older 7 Ways I’m Helping My Parents Stay Healthy As They Get Older For more on Dr. Sinha, follow him on Instagram, Facebook, YouTube, LinkedIn, Apple Podcasts, Spotify, or visit his Website. This episode is brought to you by Bon Charge, Cozy Earth, One Skin, and Maui Nui. Right now, Bon Charge is offering my community 15% off. Just go to boncharge.com/DHRU and use code DHRU to save 15%. Right now, One Skin is offering my community up to 30% off your first three subscription orders; just go to oneskin.co and use the coupon code DHRU and give your skin the scientifically proven, gentle care it deserves. Right now, Maui Nui Venison is offering my listeners exclusive access to their brand-new Always Summer Sausage, the cleanest, most nutrient-dense lunch meat you’ll find. Just go to mauinuivenison.com/DHRU to get yours today.  Right now, get 20% off your Cozy Earth sheets and sleepwear. Just head over to cozyearth.com/dhru and use code DHRU. Sign up for Dhru’s Try This Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices
This episode is brought to you by BiOptimizers and Hollow Socks. As the new year begins, what if you could set small, intentional habits that quietly compound to support your longevity, productivity, and creativity all year long? By reflecting on the past year, choosing focused micro-habits, and taking sustainable, practical steps forward, you can start shaping the life you want to live in the year ahead. Today on The Dhru Purohit Podcast, we’re revisiting one of our most popular conversations with neuroscientist Dr. Tara Swart. Dhru and Dr. Tara explore the science behind manifestation and the laws of attraction, how to set meaningful goals, and ways to build neuroplasticity through challenge. They also discuss breaking free from limiting habits and addictions, setting healthy boundaries, and share practical tools for navigating self-doubt and building confidence—making this episode a powerful listen for anyone looking to strengthen themselves, start something new, or create healthier relationships. Dr. Tara Swart is a neuroscientist, former psychiatric doctor, and senior lecturer at MIT Sloan. She is a visiting senior lecturer at King's College, London, and an executive advisor to some of the world's most respected leaders in media and business. She is the lead author of the award-winning book Neuroscience for Leadership and was named the world's first Neuroscientist in Residence at Corinthia Hotel, London. Dr. Swart is passionate about teaching others how to apply lessons from cognitive science to enhance everyday lives. In this episode, Dhru and Dr. Swart dive into: (0:00) Intro (1:02) Digital detox and why stepping away can reset your mind(2:08) Boosting boundaries, creativity, and connection to nature(14:39) Why two to three micro-habits per quarter work better than New Year’s resolutions(24:25) The power of reflecting on past wins(32:51) How challenging your brain builds neuroplasticity and growth(40:04) The science behind getting 1% better each day through small changes(49:53) Rewiring deep neural patterns and using affirmations to reinforce self-worth(58:13) Dr. Tara’s six principles for knowing you’re on the right path(1:04:53) Why manifestation can feel uncomfortable and how resilience and intuition help(1:07:36) A powerful question to face fear and uncertainty(1:11:45) Manifesting longevity by clearly defining what your life needs(1:18:21) Three warning signs a relationship may fail(1:26:34) Building a healthy relationship through connection and clear communication(1:33:47) Attracting the partner you want(1:39:12) How eye contact and laughter strengthen relationships(1:41:30) Why scheduling intimacy can help during stressful seasons(1:49:18) Why loneliness is rising and how to create real connection(1:51:55) Simple reminders to reconnect with your potential and purpose Also mentioned in this episode: The Source: The Secrets of the Universe, the Science of the Brain For more on Dr. Tara Swart, follow her on Instagram, X/Twitter, Facebook, LinkedIn, or visit her Website. This episode is brought to you by BiOptimizers and Hollow Socks. Go to bioptimizers.com/dhru now and enter promo code DHRU to get 26% off select products and bundles during their New Year New You sale. For a limited time, Hollow Socks is offering my community a Buy 3, Get 3 Free Sale. Head to HollowSocks.com for up to 50% off your order. Sign up for Dhru’s Try This Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices
This episode is brought to you by Cozy Earth, Bon Charge, and Momentous. Most people who lose weight end up regaining it, and that cycle can be even more pronounced after stopping GLP-1 medications if there isn’t a clear plan in place. Weight loss gets most of the attention, but maintenance is where people tend to struggle. Today’s guests share a practical framework for navigating that challenge and achieving long-term success. Today on The Dhru Purohit Show, Dhru sits down with Dr. Holly Wyatt and Dr. James Hill to break down what really drives long-term success with weight loss, especially in the era of GLP-1 medications. We explore why losing weight and keeping it off require different skills, why a clear maintenance plan matters as much as the initial weight loss, and how mindset and social environment can quietly make or break progress over time. Dr. Wyatt and Dr. Hill also share practical strategies for physical activity, navigating food choices, and recognizing early warning signs of weight regain before it snowballs, making this a must-listen for anyone focused on sustainable, lasting results. Dr. Holly Wyatt is a physician and endocrinologist with over 25 years of experience in weight loss and long-term weight management, known to millions from Extreme Weight Loss. She’s a coauthor of State of Slim, creator of the SOS programs, and a Professor of Nutrition Sciences at the University of Alabama at Birmingham, where she researches what it truly takes to maintain weight loss. She also co-hosts the podcast Weight Loss and…, translating science into practical strategies for everyday life. Dr. James O. Hill is one of the world’s leading obesity researchers, with over 40 years of experience studying weight regulation and metabolic health. He has published 700+ scientific papers, co-founded the National Weight Control Registry, and recently helped launch the International Weight Control Registry. Dr. Hill is a Professor of Nutrition Sciences at the University of Alabama at Birmingham, directs the Nutrition Obesity Research Center, and is the coauthor of State of Slim and The Step Diet Book. In this episode, Dhru, Dr. Wyatt, and Dr. Hill dive into:  The importance of planning for weight maintenance (1:30) Insights from the National Weight Control Registry (4:01) Understanding how GLP-1 medications work (6:30) Side effects and quality-of-life considerations (8:33) The return of hunger after stopping medications (11:35) The debate between medication and traditional methods (16:18) Chasing the perfect diet: a common mistake (24:00) Advocating for health, confidence, and self-management (29:02) Key practical recommendations for weight maintenance (39:25) Strategies for increasing protein and fiber intake (45:26) Managing liquid calories and their impact (48:44) Early warning signals for weight regain (54:48) The influence of social networks on weight (59:31) Mindset and identity in weight management (1:05:28) Physical activity that supports weight maintenance (1:10:28) Also mentioned in this episode: Losing the Weight Loss Meds: A 10-Week Playbook for Stopping GLP-1 Medications Without Regaining the Weight For more on Dr. Wyatt and Dr. Hill, follow them on Dr. Wyatt’s Instagram, Apple Podcasts, Spotify, Amazon Music, or visit their Website. This episode is brought to you by Cozy Earth, Bon Charge, and Momentous. Right now, get 20% off your Cozy Earth sheets and sleepwear. Just head over to cozyearth.com/dhru and use code DHRUP. Right now, Bon Charge is having their holiday sale and offering my community 25% off. Just go to boncharge.com/DHRU and use code DHRU to save 25% today. Optimize your energy and mental clarity with the purest form of creatine, made by and used by the best, now available in convenient and tasty lemon lime chews. Head to livemomentous.com and use code DHRU for 35% off your first subscription. Sign up for Dhru’s Try This Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices
This episode is brought to you by BetterWild. Feeling good isn’t just about avoiding illness; it’s about steady energy, clear focus, better sleep, and lower daily stress. In this episode, the conversation explores simple, practical tools, like adaptogens and smarter caffeine use, that can meaningfully improve how we feel day to day. Today on The Dhru Purohit Show, we’re revisiting one of our most talked-about moments with Tero Isokauppila. He breaks down the power of adaptogens, how they can meaningfully support health, and simple ways to start integrating them into your routine. Tero also shares his top two sleep supplements, explains how to stack adaptogens for maximum benefit, and discusses why rethinking your beliefs about sleep and cycling coffee can make a big difference. Tero Isokauppila is an expert in nutrition, health, and wellness, and the founder of Four Sigmatic, a functional foods company. He is the author of two bestselling books: Healing Mushrooms, an educational cookbook, and Santa Sold Shrooms, a children’s book for adults about the magical origins of Santa Claus, as well as Healing Adaptogens: The Definitive Guide to Using Super Herbs and Mushrooms for Your Body’s Restoration, Defense, and Performance. In this episode, Dhru and Tero dive into: The two supplements that can dramatically improve deep sleep quality (3:59) Why stacking supplements may work better than taking them alone (7:43) Simple sleep tweaks that make a bigger difference than you think (9:48) How to use adaptogens and caffeine without wrecking your energy (14:21) The key takeaways that tie it all together (24:52) Also mentioned: Full episode with Tero Isokauppila Try This: My Top Three Functional Mushrooms  Try This: Step-By-Step Sleep Protocol Try This: Why You Need a Coffee Break and How to Do It This episode is brought to you by BetterWild. Right now, BetterWild is offering my listeners up to 40% off at BetterWild.com/DHRU. Support your dog’s digestion and allergy defense system today.  Sign up for Dhru’s Try This Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices
This episode is brought to you by BiOptimizers, Ollie, and Maui Nui. As we gear up for the new year, there’s no better time to revisit tried-and-true advice from one of our favorite guests. Most people don’t struggle because they lack discipline, they struggle because they’re following guidance that was never designed to stick. In this conversation, you’ll get a practical, science-backed roadmap for building habits that actually last, so you can step into the coming year with clarity, momentum, and a plan that truly works. Today on The Dhru Purohit Show, we’re revisiting one of our most powerful conversations with personal trainer and Mind Pump Media co-founder Sal Di Stefano. We dig into the biggest pitfalls that sabotage fitness goals and prevent people from having their fittest year yet. Sal shares his top tips for incorporating underrated forms of movement, building activity into your entire day, and staying consistent for sustainable results. He also breaks down the unrealistic goals that hold people back, from a lack of specificity to an overreliance on trendy supplements. If you’re looking for inspiration to make 2026 the year of consistent, long-term progress, this episode is for you. Sal Di Stefano began his fitness journey at just 18, quickly rising to prominence as a trainer and opening some of the largest big-box gyms in the California Bay Area. By 24, he launched a wellness-focused fitness studio that combined expertise in hormones, nutrition, gut health, and fitness training. It was during this time that Sal developed his unique, behavior-focused approach to achieving lasting health and fitness success. Today, Sal is a highly sought-after expert known for his practical, easy-to-apply insights. As co-host of the Mind Pump Podcast, the world’s top fitness and health podcast, he’s appeared on hundreds of leading shows and frequently speaks at events for trainers and health practitioners. In this episode, Dhru and Sal dive into: The most underrated form of activity (00:42) Why movement results in better choices throughout the day (4:38) Getting results versus keeping results (9:36) Unrealistic approach to calorie cutting and how to build a proper foundation (14:06) Nutritional advice or myths we can leave behind (18:53) Insights into the fitness and wellness industry (30:42) The one supplement Sal recommends and the research behind its effectiveness (33:53) How to use caffeine appropriately (39:42) Being specific with your goals and focusing on one at a time (44:51) Prioritizing simple whole foods and fiber (50:47) The risks of sitting too much and how to counteract them (56:11) How to get started with a sustainable routine (1:02:04) Over-exercising and finding balance (1:05:17) Final thoughts and key takeaways (1:09:32) Also mentioned in this episode: MAPS 15 Fitness Programs Why You Need A Coffee Break and How to Do It For more on Sal and Mind Pump, follow them on Facebook, X/Twitter, Instagram, Apple Podcasts, TikTok, YouTube, and their Website. This episode is brought to you by BiOptimizers, Ollie, and Maui Nui. Upgrade your digestion with enzymes! Go to bioptimizers.com/dhru now and enter promo code DHRU to get 15% off any order of MassZymes today.  Want to give your dog the best in clean eating? Take the online quiz and introduce Ollie to your pet. Right now, Ollie is offering 60% off your first box of meals when you subscribe today! Just head to Ollie.com, use the code DHRU, and you’ll get 60% off your first box of meals in your subscription. Right now, Maui Nui is giving my listeners early access to their Holiday Gift Sets—and when you buy four, you get a fifth free. Just go to mauinuivenison.com/DHRU to claim yours. Quantities are limited, so don’t wait! Sign up for Dhru’s Try This Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices
This episode is brought to you by Branch Basics and BetterWild. As we get older, protecting brain health becomes more important than ever, and it’s becoming increasingly clear how powerfully everyday inputs shape the brain, often long before any cognitive symptoms appear. The good news is that simple, daily choices can have a massive impact on brain resilience and long-term cognitive strength.  Today on The Dhru Purohit Show, we’re revisiting one of our most talked-about moments with Dr. Datis Kharrazian. He breaks down the top foods that may accelerate early brain aging, including why seed oils are a growing concern. Dr. Kharrazian and Dhru also explore the connection between leaky gut and brain health, as well as the conditions linked to both. Plus, he shares his top supplement recommendations to support brain health and help prevent cognitive decline. Dr. Datis Kharrazian is a clinical research scientist, an academic professor, and a Functional Medicine healthcare provider. He is an associate clinical professor at Loma Linda University School of Medicine, a research fellow at Harvard Medical School, and a researcher at the Department of Neurology at Massachusetts General Hospital. In this episode, Dhru and Dr. Kharrazian dive into: The everyday foods quietly accelerating brain aging (2:02) Why seed oil consumption deserves a second look (4:50) Leaky gut, leaky brain: the connection most people miss (10:52) Why glutathione matters for calming brain inflammation (14:22) Dr. Kharrazian’s top supplement picks for brain health (22:47) Final takeaways you’ll want to remember (29:49) Also mentioned: Full episode with Dr. Datis Kharrazian Try This: The Power of Glutathione Glutathione: Your Most Important Defense  This episode is brought to you by Branch Basics and BetterWild. Right now, Branch Basics is offering 15% off the Premium Starter Kit; just go to branchbasics.com and use the coupon code DHRU. Transform your space, transform your health, start with Branch Basics today. Right now, BetterWild is offering my listeners up to 40% off at BetterWild.com/DHRU. Support your dog’s digestion and allergy defense system today.  Sign up for Dhru’s Try This Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices
This episode is brought to you by LMNT, Cozy Earth, Fatty15, and Maui Nui. We all know muscle is important, but today’s guest takes it a step further, showing why it can truly be a life-changing, even life-saving, part of our health. He shares what his deep-dive research uncovered about the history of muscle and strength training, how our relationship with it has evolved, and what those shifts can teach us about building a stronger, more resilient population today. Today on The Dhru Purohit Show, Dhru sits down with Michael Gross to explore the profound impact of muscle and strength training on health, longevity, and identity. They discuss the importance of muscle mass in preventing chronic diseases, the role of strength in shaping personal identity, and share inspiring stories of transformation. Michael emphasizes that it's never too late to start strength training and highlights the need for a shift in the medical community to recognize exercise as a vital component of health care. Michael Joseph Gross began his career as a political speechwriter before moving into journalism, writing for major newspapers and magazines. As a longtime contributing editor at Vanity Fair, he covered culture, politics, religion, crime, business, technology, and national security, and appeared on programs such as CBS Mornings, Morning Joe, and NPR. He is the author of Starstruck: When A Fan Gets Close to Fame and Stronger: The Untold Story of Muscle in Our Lives, which explores the central role of muscle in human health and history. In this episode, Dhru and Michael dive into:  How muscle impacts cancer and diabetes risk (5:46) Muscle mass as the body’s glucose-disposal engine (9:49) The link between muscle strength and cognitive health (14:36) Why the medical system overlooks muscle  and why it matters (19:42) Jan Todd’s story and what it teaches us about self-efficacy (30:04) Why it’s never too late to start strength training (47:34) Ancient Greek wisdom on strength and vitality (52:41) How strength and community shape each other (57:26) The future: prescribing strength training as medicine (1:01:54) Strength training as a deeper life practice (1:11:10) Breakthrough research on strength training for seniors (1:15:06) Michael’s personal stories on strength and quality of life (1:23:45) Final thoughts and key takeaways (1:28:15) Also mentioned in this episode: STRONGER: The Untold Story of Muscle in Our Lives Oldest Female Ninja Warrior: A Longevity Protocol To Stop Decline, Stay Young & Build Muscle! 7 Ways I'm Helping My Parents Stay Healthy As They Get Older For more on Michael, follow him on Instagram or visit his Website. This episode is brought to you by LMNT, Cozy Earth, Fatty15, and Maui Nui. Right now, LMNT is offering my listeners a free sample pack with any purchase. Head over to drinkLMNT.com/dhru today. Right now, get 20% off your Cozy Earth sheets and sleepwear. Just head over to cozyearth.com/dhru and use code DHRUP. Fatty15 is offering an additional 15% off its 90-day subscription Starter Kit. Go to fatty15.com/dhru and use code DHRU to replenish your C15 levels for long-term health. Right now, Maui Nui is giving my listeners early access to their Holiday Gift Sets—and when you buy four, you get a fifth free. Just go to mauinuivenison.com/DHRU to claim yours. Quantities are limited, so don’t wait! Sign up for Dhru’s Try This Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices
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Comments (35)

narmin HN

could you please put the name of the person you talk with at the title of episode? Or her/his picture on the episodes picture? It would be a great help to finde the desierd episode.

Feb 5th
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Alexandra Victoria

This episode must have been the best one I've heard on Narcissism. Thank you!

Oct 16th
Reply

Alexandra Victoria

Have to love Gabor!

Sep 28th
Reply

Sue Knox

great episode. thank you

May 21st
Reply

Andrea Madsen

I just ordered this book. Stuart makes sense!

May 19th
Reply

Yulia Volyanskaya

This is a great podcast, it provides practical, actionable advice based on scientific research. I appreciate the guest selection: Dhru hosts a variety of esteemed guests, including leading researchers and practitioners. This variety adds depth and multiple perspectives to the discussions!

May 3rd
Reply

Ann Marie

I heard found Dhru through a random search on health, and he made a lot of sense- I have been a regular listener for several years- he has great guests asks probing questions and I have found several others to learn from in this category- Thank you Dhru!

May 3rd
Reply

selena

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Mar 16th
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A J

this was interesting, although he stigmatizes drug users with comments like "ew, drug user brain". the free will comments were helpful as well.

Mar 25th
Reply

Stephanie Banks

Best podcast on cold water therapy yet!

Mar 16th
Reply

Pooneh

I listen to your podcast while I’m preparing meals for my work week and just wanted to let you know how inspiring this podcast and how good it makes me feel about the food I’m making. It makes being questioned by my fast food eating coworkers about what I’m eating worth it.

Feb 4th
Reply

Annika Ringaby Woehr

Such an excellent episode. Many important tools that anyone can learn.

Jan 4th
Reply

Maximus Meridius

How in the world can you say that sugar and insulin spike and that's not a problem?

Dec 28th
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Martin Chan

Loved it. I listen to all you podcast, look forward to them and pass themon to close friendsat work.. Cheers.

Feb 6th
Reply

Thomas Lambrecht

A much needed peptalk to scare away the winterblues

Jan 5th
Reply

David Nicolas

Love the breath knowledge from James Nestor

Dec 30th
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Alexandra Victoria

love this, thank you!

Dec 16th
Reply

Jabina Chowdhury

I love that it gets straight to the point

Jul 24th
Reply

Lyle Lehman

Miu m

Jun 16th
Reply (1)

Annika Ringaby Woehr

soooooo good! thank you for introducing me to this artist! I will buy his book. Such deep and important conversations!!

Apr 5th
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