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Simply Oncology

Author: John McGrane & Michael Rowe

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Welcome to Simply Oncology. 
Cancer is daunting for both patients and for clinical teams.
Dr John McGrane and Dr Michael Rowe are oncologists who want to break down the complex parts of cancer care into clear and simple sessions.
We will dive deep into the world of cancer research, patient stories and the latest cancer breakthroughs. 
Simply Oncology will have patient focused episodes along with episodes that allow anyone with an interest in oncology to stay up to date.

We hope you join us as we unpick all parts of cancer. 

John & Mike

92 Episodes
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Send a text Join us as return to our excellent conversation on biomarkers in kidney cancer with the wonderful Professor Laurence Albiges from Paris. 🎙️We finish our overview of Biomarkers in metastatic Kidney Cancer with the superb Professor Laurence Albiges from the Gustave Roussy Hospital in Paris 🇫🇷 Which biomarker will help us to decide which treatment to select in metastatic #KidneyCancer - IOIO vs IOTKi - when to start therapy - monitoring on treatment An exciting space an...
Send a text Join us for a special Kidney Cancer treat!!! A Must Listen episode!! We discuss the role of biomarkers in advanced kidney cancer with the wonderful Professor Laurence Albiges from the Gustave Roussy Institute of Oncology in Paris. No Kidney Cancer talk is complete without the question -" Where are we with biomarkers?" This is part 1 of a 2 part walkthrough of the biomarker story so far in kidney cancer. Laurence is unequalled in her clear delivery on this subject. As lead for the ...
Send a text Join us as we return to complete our run through the landscape of metastatic renal cancer with the effervescent Professor Ricky Frazer. We look at the Dolly Mixture of subtypes that makes up non clear cell renal carcinoma. We discuss the new HIF2a inhibitors such as belzutifan. We look at future directions in kidney cancer. A treat for anyone who treats kidney cancer. Enjoy!
Send a text Join us is as we celebrate Kidney Cancer week with a Masterclass walk through metastatic Renal Cancer with Professor Ricky Frazer from Velindre Cancer Centre. Ricky is a co-host of the hugely successful Immunobuddies podcast and has a vast experience in immunotherapy management. We look at the indications for immunotherapy versus anti-VEGF TKI therapy. Should we just accept anti-VEGF TKI monotherapy in Favourable Risk patients? When should we try IO/IO combination versus IO/TKI co...
Send a text Join us for Part 2 of our Metastatic Endometrial Cancer special with the amazing Dr Gemma Eminowicz from University College London Hospital. In episode 1 we looked at molecular profiling and immunotherapy. In this episode we explore the role of; - hormone therapy - Antibody drug conjugates - PARP inhibitors Endometrial cancer is taking off in terms of new and exciting treatment options. Gemma does an amazing job talking us through them. Enjoy.
Send a text Dr Gemma Eminowicz returns for 2026!! Join us as we discuss the metastatic endometrial cancer landscape with Simply Oncology 'friend of the show' Dr Gemma Eminowicz from University College Hospital London. Advanced endometrial cancer is so much more than carboplatin and paclitaxel. It now has the complete range of oncological treatments; - Chemotherapy - Immunotherapy - Antibody Drug Conjugates - Hormone therapy - Targeted therapy - Radiotherapy We look at how the molecular testin...
Send a text We return for part 2 of our overview on metastatic oesphago-gastric cancer. Join us as we welcome back Dr Lizzy Smyth from Oxford University Hospitals. We look at the importance of nutritional support. We discuss future directions such as CAR-T therapy Lizzy mocks John (again!!) A brilliant finish to our OG masterclass from Lizzy. Enjoy!
Send a text Dr Lizzie Smith from Oxford University Hospitals gives us a an amazing 2 part overview of management of metastatic Oesophago-Gastric cancer. We discuss molecular testing and therapy options in metastatic OG cancer🧬 HER2 PDL 1 Claudin 18.2 Lizzy is a hugely respected figure in OG cancer and key clinical trialist! John gets put in his place by Lizzy on several occasions!! Lizzy has a way of describing things that even John could understand!! Part 1 of 2 in this metastatic OG mas...
Send a text Happy New Year!!! WE return in 2026 to complete our overview of PARPi in prostate cancer with the peerless Professor Rob Jones.
Send a text Join us as we unwind in the Christmas Holiday period with a masterful overview of PARP inhibitors in metastatic prostate cancer with Professor Rob Jones. Rob is an old friend of the show and is amazing at setting the scene for who & when PARP inhibitors can be useful in metastatic prostate cancer.
Send a text Welcome back! In part 1 we discussed the major effects of menopause and how these can be worsened by hormonal medications given to treat breast cancer and the impact these can have on patients completing treatment as planned. In this episode we welcome back Dr Rebecca Bowen and discuss practical advice on managing these symptoms including a link to what will be a vital resource for all clinicians in Oncology and Primary Care: the Meno.Pause app. Link below, download today! Meno....
Send a text When is it safe to giving HRT in women who are being treated or have previously been diagnosed with breast cancer? Will the use of vaginal oestrogens affect breast cancer outcomes? What is the trade off on quality of life when symptoms of the menopause aren't managed? Did you know that roughly 1 in 4 women stop their hormone therapy for breast cancer due to menopausal side effects!! Who better to answer these questions and more than Dr Rebecca Bowen, Consultant Oncologist in Royal...
Send a text Sexual health in cancer is a topic we need to talk more about. So many patients feel unable to discuss their sexual health and also clinical teams don’t also mange to bring the topic up. A cancer diagnosis can affect self image and confidence. We talk to Lorraine Grover who is a sexual health specialist nurse about how we can break down some of these barriers. Erectile dysfunction and much more discussed. You may never look at a Calypo ice lolly the same again !! This episod...
Send a text We return to Part 2 of our walk through metastatic bowel cancer with the excellent Professor Naureen Starling. We look at RAS, BRAF and future directions for treatment of metastatic bowel cancer. Can ctDNA have a role in metastatic bowel cancer? What role may HER2 have to play going forward? What is exciting on the horizon in mCRC? Enjoy!!
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Send a text Join us as we return for Part 2 with the superb Dr Alison Berner. It’s Transgender Awareness Week and we discuss resources to support patients and clinicians. We discuss OUTpatients and UCATS - UK cancer and transition service.
Send a text As we approach transgender awareness week we discuss cancer care in the transgender community with the exceptional Dr Alison Berner. 1 in 40 people aged under 30 identify as transgender in recent census. How we give support needed and signpost patients can have a huge influence on their experience of care. Alison has done so much work in this area. We learned a lot in this episode and we hope you enjoy! https://outpatients.org.uk/ https://www.wearetransplus.co.uk/uk-cancer-and-t...
Send a text We return to discuss stereotactic radiotherapy (SABR) in prostate cancer with the superb Dr Alison Tree from The Royal Marsden Hospital. We discuss the findings of the TRAP study which extended time to next treatment by 6 months when SABR was used for sites of growing disease. Do we always need to change systemic therapy when only one or two sites of metastatic disease is growing??
Send a text We are back for part 2 to finish our journey through the Gut Microbiome with the excellent Professor Monty Pal !! Few areas of cancer treatment have generated as much interest as the Gut Microbiome in recent years. We discuss work done by Monty's team on CBM588 on immunotherapy in kidney cancer. CBM 588 is a live bacterial product that is available in health shops in Japan where it is used to promote a healthy gut. Monty's team found incredible results where it improved resp...
Send a text Did you know that we have more bacterial DNA than human DNA in our bodies. This is because our guts contain trillions of bacteria and are now being thought of as another organ of the body. Join us this week as we discuss the Gut Microbiome (part 1 of 2) and its importance on drugs like immunotherapy response in cancer. We talk to none other than the excellent Professor Monty Pal from The City of Hope Hospital in California. Monty is an internationally respected kidney cancer exper...
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