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ZOE Science & Nutrition

ZOE Science & Nutrition

Author: ZOE

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The world’s top scientists explain the latest health, nutrition, and gut health research and translate it into practical advice to improve your health & weight. Join ZOE Science & Nutrition, on a journey of scientific discovery. Hosted by Jonathan Wolf.

350 Episodes
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Picture the sound of a bone snapping - the kind of sound that makes you wince - and ask yourself how often you’ve thought about your bone health. Most of us only think about bone density when something breaks. Until then, your bones stay almost invisible, carrying you through every day. In today’s episode, Professor Elaine Dennison, a world-leading expert in bone health, explains why that needs to change, why stronger bones are key to living more healthy years, and why declining bone health isn’t inevitable. Elaine explains why it’s not just about avoiding broken bones, but about learning to understand one of the most important living tissues in your body. By the end of the episode, you’ll know exactly how to protect your bones so they can look after you now and for many years to come. Could your bones be the missing anti-aging link you’ve been missing? 🌱 Try our science-backed and tasty wholefood supplement Daily30 🌿Let your gut microbes snack on the ZOE Gut Health Bar Build healthy habits. Download the ZOE app today and start your trial for just £2.30 for your first week. 👉 Join ZOE Follow ZOE on Instagram. Timecodes 00:00 Intro 03:05 Are your bones dead tissue? The truth about bone biology 08:08 Peak bone mass: the age your bones stop getting stronger 11:06 What is osteoporosis? The condition you won't feel coming 14:01 Spinal fractures and death risk: what the research shows 15:53 What does osteoporosis do to your bones? The honeycomb explanation 17:46 Fragility fractures: why older adults break bones from a simple fall 20:02 Bone marrow function: what your bones do for your immune system 22:48 The gut-bone axis: how gut health affects bone health 27:01 Does stress affect bone health? The cortisol connection 29:45 Is alcohol good or bad for bone health? The surprising answer 30:16 Does extra weight protect your bones? What the science says 32:13 GLP-1 drugs and bone health: the risk no one's talking about 33:21 Muscle loss and bone density: why they're linked 35:37 DEXA scan: the only way to know your bone density 39:06 Osteoporosis medication: how doctors treat bone loss 40:51 Best exercise for bone density: why walking isn't enough 42:54 How much calcium do you need a day for strong bones? 44:04 Vitamin D and bone health: why you need it to absorb calcium 45:41 Why vitamin D deficiency is common in sunny Australia 47:22 Does HRT protect your bones? The benefits and risks explained 48:31 Do weighted vests improve bone density? What the evidence shows 49:44 How to improve bone health: the first steps to take 📚Books by our ZOE Scientists The Food For Life Cookbook Every Body Should Know This by Dr Federica Amati The Appetite Reset by Dr Federica Amati Food For Life by Prof. Tim Spector Ferment by Prof. Tim Spector Good Mood Food (preorder) by Prof. Tim Spector Free resources from ZOE The Smart Snacking Guide: How to feed your gut, fuel your day, and snack without guilt The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra   Eating for Better Brain Health: Your brain-gut blueprint How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health Live Healthier: Top 10 Tips From ZOE Science & Nutrition Gut Guide - For a Healthier Microbiome in Weeks  Better Breakfast Guide Mentioned in today's episode The effect of Daily30 on Gut Health, Energy Levels, and Hunger in Healthy Adults, Cambridge University Press (2026) Mortality Rate in Patients with Vertebral Compression Fractures, Geriatric orthopaedic surgery & rehabilitation (2023) The Influence of the Mediterranean Diet on Bone Health, Nutrients (2023)  Have feedback or a topic you'd like us to cover? Let us know here. Episode transcripts are available here.
We’ve all heard the saying: Breakfast is the most important meal of the day. And while it may sound like a cliché, there’s some truth to it. Because for many of us, breakfast is the one meal we keep the same - day after day, morning after morning.  This consistency means our breakfast choices have a powerful influence on our long-term health. So, today I’m joined by Tim Spector and behaviour expert Professor Ben Gardner to share practical ways to break out of unhealthy routines and build a breakfast habit that will support you every single morning. 🌱 Try our science-backed and tasty wholefood supplement Daily30 🌿Let your gut microbes snack on the ZOE Gut Health Bar Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE Follow ZOE on Instagram. 📚Books by our ZOE Scientists The Food For Life Cookbook Every Body Should Know This by Dr Federica Amati The Appetite Reset by Dr Federica Amati Food For Life by Prof. Tim Spector Ferment by Prof. Tim Spector Good Mood Food (preorder) by Prof. Tim Spector Free resources from ZOE The Smart Snacking Guide: How to feed your gut, fuel your day, and snack without guilt The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra   Eating for Better Brain Health: Your brain-gut blueprint How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health Live Healthier: Top 10 Tips From ZOE Science & Nutrition Gut Guide - For a Healthier Microbiome in Weeks  Better Breakfast Guide Have feedback or a topic you'd like us to cover? Let us know here. Episode transcripts are available here.
Are some of your "healthy" foods actually high-risk ultra-processed foods?  For decades, nutrition advice seemed relatively straightforward. Eat less sugar. Less salt. Less saturated fat. Then it all fell apart. In today’s episode, we examine the research that has forced us to rethink what makes food harmful in the first place. Two of the world’s leading nutrition scientists, Professor Tim Spector and Professor Sarah Berry, tell their own story of why they’ve changed their minds about it. We explore why sugar, salt and fat aren’t the whole story, explain why ultra-processed foods are making us sick, and share groundbreaking insight that only a small portion of them are really harmful. By the end of the episode, you’ll know what to watch out for and what to worry less about when you’re food shopping. Next time you reach for a "healthy" yogurt or a quick pasta sauce, would you still choose it if you knew exactly how it was made? 🌱 Try our science-backed and tasty wholefood supplement Daily30 🌿Let your gut microbes snack on the ZOE Gut Health Bar Build healthy habits. Download the ZOE app today and start your trial for just £2.30 for your first week. 👉 Join ZOE Follow ZOE on Instagram. Timecodes 00:00 Intro 02:24 The biggest myth about spotting ultra-processed food 07:52 How much of your diet is actually ultra-processed 12:09 Why people ate 500 more calories on ultra-processed food 13:47 The study that changed how scientists see ultra-processed food 17:52 The hidden artificial sweeteners nobody noticed they were eating 20:29 What sweeteners did to mice in this gut bacteria experiment 23:57 What emulsifiers might be doing to your gut lining 28:27 Why food additive combinations are impossible to track 31:30 Can food texture alone change how much you eat? 33:08 Two ultra-processed diets, 369 calories apart 37:10 How the tobacco industry invented food's "bliss point" 39:33 Why hyperpalatable food makes you eat the whole bag 42:17 Does skipping cakes and soda avoid ultra-processed food? 46:38 The "ultra-processed" foods that are actually protective 48:32 How ZOE built its own ultra-processed food risk score 51:01 Why 72 calories a minute is one sign of a risky food 53:48 The 25% of ultra-processed food causing most of the harm 56:11 The one-question test for spotting ultra-processed food 59:32 ZOE says 25% of food is high risk, not NOVA's 60% 01:01:54 Why some "healthy" yogurts are full of hidden sweeteners 01:03:16 Why children's food is designed to make kids overeat 01:05:41 Two pestos, one full of hidden sweeteners 01:10:20 Ultra-processed food uses the same trick as cigarettes 01:11:41 Why you shouldn't fear all processed food 📚Books by our ZOE Scientists The Food For Life Cookbook Every Body Should Know This by Dr Federica Amati The Appetite Reset by Dr Federica Amati Food For Life by Prof. Tim Spector Ferment by Prof. Tim Spector Good Mood Food (preorder) by Prof. Tim Spector Free resources from ZOE The Smart Snacking Guide: How to feed your gut, fuel your day, and snack without guilt The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra   Eating for Better Brain Health: Your brain-gut blueprint How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health Live Healthier: Top 10 Tips From ZOE Science & Nutrition Gut Guide - For a Healthier Microbiome in Weeks  Better Breakfast Guide Mentioned in today's episode Ultra-Processed Diets Cause Excess Calorie Intake and Weight Gain, Cell (2019) Personalized microbiome-driven effects of sweeteners, Cell (2022) Food Emulsifiers and Metabolic Syndrome: The Role of the Gut Microbiota, Foods (2022) NutriNet-Santé Study Eating rate has sustained effects on energy intake from ultraprocessed diets, The American Journal of Clinical Nutrition (2026) The role of hyper-palatable foods in energy intake, Eating Behaviours (2025) ZOE’s PREDICT studies: What we’ve learned Episode transcripts are available here.
Floating through all of our bodies is a complex network of hormones. You can think of it as an internal postal service, delivering vital messages and instructions to different organs and systems. But what happens if these messages get intercepted, mixed up, or worse, not delivered at all? In this episode, Dr Andrew Jenkinson tells us about a hormone that plays a crucial role in weight regulation and the undesirable consequences when it isn’t functioning properly. He also shares three simple tips you can do tomorrow to make sure your hormones support your health. 🌱 Try our science-backed and tasty wholefood supplement Daily30 🌿Let your gut microbes snack on the ZOE Gut Health Bar Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE Follow ZOE on Instagram. 📚Books by our ZOE Scientists The Food For Life Cookbook Every Body Should Know This by Dr Federica Amati The Appetite Reset by Dr Federica Amati Food For Life by Prof. Tim Spector Ferment by Prof. Tim Spector Good Mood Food (preorder) by Prof. Tim Spector Free resources from ZOE The Smart Snacking Guide: How to feed your gut, fuel your day, and snack without guilt The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra   Eating for Better Brain Health: Your brain-gut blueprint How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health Live Healthier: Top 10 Tips From ZOE Science & Nutrition Gut Guide - For a Healthier Microbiome in Weeks  Better Breakfast Guide Have feedback or a topic you'd like us to cover? Let us know here Listen to the full episode here
Growing up, many of us were taught to just stay calm and carry on - as if stress was all in the mind, with no real effect on the body. But chronic stress can change your brain, raise your risk of heart disease, and even shorten your life.  In this episode, we ask: what happens when a stress response built to last minutes never switches off? Today, Professor Carmine Pariante, one of the world's leading researchers on stress, helps us understand what’s happening in your body during a stressful moment and why chronic stress disrupts sleep, appetite, and energy levels. Carmine also explains how worried you should be about cortisol, and whether "cortisol face" and "cortisol belly" are backed by evidence. By the end, you’ll understand why stress can be so powerful, when it becomes harmful, and have some evidence-based ways to manage it. Next time you reach for wine, your phone, or something sweet after a hard day, ask yourself: is this helping you cope, or helping you avoid how you feel? 🌱 Try our science-backed and tasty wholefood supplement Daily30 🌿Let your gut microbes snack on the ZOE Gut Health Bar Build healthy habits. Download the ZOE app today and start your trial for just £2.30 for your first week. 👉 Join ZOE Follow ZOE on Instagram. Timecodes 00:00 Intro 01:10 Should you be aiming for zero stress? 06:13 Inside your fight-or-flight response 11:19 Can stress actually cause a heart attack? 13:15 Why your stress response won't switch off 15:33 Why stress eating isn't a willpower problem 17:15 Why emotional stress feels physical 21:00 The earliest sign of chronic stress 22:05 There's no such thing as "it's all in your head" 25:15 Stress causes the same inflammation as a cold 29:54 The blunt truth about chronic stress 31:07 How stress clogs your arteries 32:55 Why chronic stress can steal your joy 35:10 What a brain scan reveals about chronic stress 37:07 Is "cortisol face" actually real? 38:49 Does the viral cortisol cocktail actually work? 41:20 Why control is the key to coping with stress 42:46 How singing for one hour lowered cortisol 45:15 Why exercise is such powerful stress relief 47:57 Foods with the strongest evidence against stress 49:45 Why alcohol doesn't actually relieve stress 50:58 Is your phone making your stress worse? 54:04 The first thing to do when stress overwhelms you 56:06 Why modern life never switches your stress off 📚Books by our ZOE Scientists The Food For Life Cookbook Every Body Should Know This by Dr Federica Amati The Appetite Reset by Dr Federica Amati Food For Life by Prof. Tim Spector Ferment by Prof. Tim Spector Good Mood Food (preorder) by Prof. Tim Spector Free resources from ZOE The Smart Snacking Guide: How to feed your gut, fuel your day, and snack without guilt The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra   Eating for Better Brain Health: Your brain-gut blueprint How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health Live Healthier: Top 10 Tips From ZOE Science & Nutrition Gut Guide - For a Healthier Microbiome in Weeks  Better Breakfast Guide Mentioned in today's episode Effect of anti-inflammatory treatment on depressive symptom severity, The American Journal of Psychiatry (2025) Implementing a group singing intervention for depression, Frontiers in Medicine (2024) The Relationship between Diet and the Occurrence of Depressive Symptoms, Nutrients (2023) Have feedback or a topic you'd like us to cover? Let us know here. Episode transcripts are available here.
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