49ers Talk: A San Francisco 49ers Podcast

The 49ers enter Week 6 of the 2026 NFL season undefeated, but not unscathed as Deebo Samuel is the latest to join their list of injured players. Could San Francisco again look to a former wideout to help them bolster their air attack? On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan discuss the availability of fan-favorite Jauan Jennings and detail the impact of Dre Greenlaw's looming suspension. Later, Matt sits down with legendary NFL reporter Peter King, who provides insight into two of the most successful eras in 49ers football under Bill Walsh and Kyle Shanahan.--(0:00) 49ers go into Week 6 undefeated, but not unscathed(3:30) How Deebo Samuel’s injury impacts an already injured WR room(10:30) Dre Greenlaw’s one-game suspension upheld by league office(16:30) Reacting to reports that Jauan Jennings could be available(26:00) 49ers have been active at trade deadline in Shanahan-Lynch era(29:30) The latest on 49ers players' ability to return in Week 6(32:00) Kudos to Special Teams - P Corliss Waitman(35:00) Former NFL reporter Peter King Interview Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

For the third time in the Kyle Shanahan era, the 49ers are 5-0 after a Week 5 brawl against the Seahawks. San Francisco dug deep to overcome miscues and injuries in a 32-29 win that made a statement around the league. On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan discuss how the 49ers escaped a hostile Lumen Field environment with their most impressive victory of the young 2026 NFL season, and break down standout performances by Mike Evans and a defense led by young talent.--(0:00) 49ers stay undefeated in instant classic vs. Seahawks(5:00) Mike Evans proves his worth in another herculean effort(13:00) Defense shows up in big way for win(17:00) Renardo Green finds redemption in Seattle(20:00) 49ers see rare production from young players(30:00) How special teams made impact in Week 5(32:00) 49ers get thinner at WR with Deebo Samuel injury(39:00) 49ers have set themselves up nicely with 5-0 start Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

One of the biggest matchups in the NFL in Week 5 sees two rivals suit up in a tug-of-war for divisional dominance. San Francisco embarks on the short trip to Seattle this weekend with more than bragging rights on their minds. "49ers Talk" host Matt Maiocco previews this epic matchup with Kyle Shanahan in his weekly sit-down with the coach. Shanahan breaks down how the 49ers prepared this offseason to counter a Seahawks team that seemed to have San Francisco's number late last season on their way to a Super Bowl win. Also, Matt reviews which 49ers players will be available in this crucial early-season barometer of strength and provides a much-anticipated update on Nick Bosa's return.--(0:00) Another early-season test for the 49ers(3:00) Update on Nick Bosa's return from injured calf(6:00) The 49ers pass rush is still an area of concern(8:00) The 49ers injury report(15:00) Kyle Shanahan Game Plan interview ahead of Week 5 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

San Francisco hasn't forgotten how last season ended in an NFC Divisional Playoff loss to the Seahawks at Lumen Field. On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan preview the 49ers' first crack at redemption against their NFC West rival in Week 5, and who will be available for the game as second-year defensive end Mykel Williams looks ready to make his season debut. Later, Matt talks with former NFL executive and agent Andrew Brandt about the business side of sports as they delve into the nitty-gritty of balancing professional contracts and salary caps.--(0:00) NFC West matchup brings extra juice in Week 5(5:00) 49ers playing numbers game with roster decisions(8:00) When is Bosa coming back?(10:00) Mykel Williams itching to return(19:00) Purdy having an elite start to season(40:00) Brandt breaks down how 49ers deal with Bosa’s massive contract next season Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

San Francisco survived inhospitable heat and a bruising Broncos defense in its 24-14 win on Sunday at Levi's Stadium, improving to 4-0. The victory did come with collateral damage, with injuries to fullback Kyle Juszczyk, corner Upton Stout and safety Marques Sigle. The Broncos suffered significant injuries of their own in DBs Pat Surtain II and Riley Moss, while WR Pat Bryant was carted off the field with an ankle injury. On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan discuss how the 49ers battled through one of their toughest opponents yet while relying on the star-studded veteran core they've invested in for years. As their division arch-rival showdown with the Seattle Seahawks looms in Week 5, San Francisco has passed one of their biggest tests in Week 4.--0:00) Early takeaways from Week 4 win vs. Broncos(9:00) 49ers superstars showed up, showed out for win(10:00) Why Deebo Samuel’s signing has been a revelation(15:00) Brock Purdy ultimately had Purdy-type game(20:00) Dre Greenlaw had point to prove vs. Broncos(33:00) 49ers head to Seattle in Week 5 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.