GasGasGas - The FRCA Primary Exam Podcast

Clonidine is a drug found in many a cupboard, acting as a useful adjunct for pain, sedation and having utility in smoothing out post op emergence, it has off license use as a adjunct in regional and neuraxial blockade (at least in the literature!) GasGasGas - putting knowledge in your brain! Show notes at: https://gasgasgas.uk/clonidine/ A podcast for the Primary FRCA Exams ———————— Donations to keep the lights on willingly accepted! Dr Gas Lurks on:  BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X FaceBook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk   Disclaimer / Sage Advice All content is educational in nature, but is never intended to be acted upon independent of organised educational and training structures, and under appropriate supervision for your stage of training.  This information is not a suitable substitute for medical advice and requests for medical advice will not be acted upon. Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present.   Music Credit: Streets of Sant Ivo - Mid-Air Machine - Free music archive Sassy Jazzy - La Faena - Free music archive #FOAMed #frcaprimary #frca #Anaesthetics #Anaesthesia  #Pharmacology #primaryFRCA #GasGasGas

Dexemedetomidine is a drug that it seems we are really only just getting our hands on in the UK, it is an Alpha 2 AGOnist causing sedation, anxiolysis and some analgesia.  This episode of GasGasGas explores its use, mechanisms side effect profile and kinetics GasGasGas - putting knowledge in your brain! Show notes at: https://gasgasgas.uk/dexmedetomidine/ A podcast for the Primary FRCA Exams ———————— Donations to keep the lights on willingly accepted! Dr Gas Lurks on:  BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X FaceBook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk   Disclaimer / Sage Advice All content is educational in nature, but is never intended to be acted upon independent of organised educational and training structures, and under appropriate supervision for your stage of training.  This information is not a suitable substitute for medical advice and requests for medical advice will not be acted upon. Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present.   Music Credit: Streets of Sant Ivo - Mid-Air Machine - Free music archive Sassy Jazzy - La Faena - Free music archive #FOAMed #frcaprimary #frca #Anaesthetics #Anaesthesia  #Pharmacology #primaryFRCA #GasGasGas

Midazolam represents the cornerstone benzodiazepine in perioperative medicine, offering rapid onset sedation, anxiolysis, and amnesia with predictable pharmacokinetics. Understanding its mechanism, dosing strategies, and clinical applications is fundamental for safe anaesthetic practice and optimal patient care. GasGasGas - putting knowledge in your brain! Show notes at: https://gasgasgas.uk/midazolam/ A podcast for the Primary FRCA Exams ———————— Donations to keep the lights on willingly accepted! Dr Gas Lurks on:  BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X FaceBook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk   Disclaimer / Sage Advice All content is educational in nature, but is never intended to be acted upon independent of organised educational and training structures, and under appropriate supervision for your stage of training.  This information is not a suitable substitute for medical advice and requests for medical advice will not be acted upon. Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present.   Music Credit: Streets of Sant Ivo - Mid-Air Machine - Free music archive Sassy Jazzy - La Faena - Free music archive #FOAMed #frcaprimary #frca #Anaesthetics #Anaesthesia  #Pharmacology #primaryFRCA #GasGasGas

Having an Iota of a Scooby-Doo about Etomidate is perhaps what is required for the FRCA primary exams. We've gone into naturally more detail when we're talking Etomidate for gasgasgas, because we love a bit of detail. This episode covers the pharmacodynamics and pharmacokinetics of Entomidate, but also explores briefly steroidogenesis and what the implications of this is clinically  GasGasGas - putting knowledge in your brain! Show notes at: https://gasgasgas.uk/etomidate-for-the-frca/ A podcast for the Primary FRCA Exams ———————— Donations to keep the lights on willingly accepted! Dr Gas Lurks on:  BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X FaceBook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk   Disclaimer / Sage Advice All content is educational in nature, but is never intended to be acted upon independent of organised educational and training structures, and under appropriate supervision for your stage of training.  This information is not a suitable substitute for medical advice and requests for medical advice will not be acted upon. Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present.   Music Credit: Streets of Sant Ivo - Mid-Air Machine - Free music archive Sassy Jazzy - La Faena - Free music archive #FOAMed #frcaprimary #frca #Anaesthetics #Anaesthesia  #Pharmacology #primaryFRCA #GasGasGas

Understanding molecular stereochemistry is fundamental to modern anaesthetic practice. The three-dimensional arrangement of atoms within drug molecules directly impacts their pharmacological properties, with some arrangements being therapeutically beneficial while others may be inactive or even harmful. This episode explores the critical concept of isomerism in anaesthetic drugs, with particular focus on how molecular handedness affects drug choice. GasGasGas - putting knowledge in your brain! Show notes at: https://gasgasgas.uk/classifying-isomers/  A podcast for the Primary FRCA Exams ———————— Donations to keep the lights on willingly accepted! Dr Gas Lurks on:  BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X FaceBook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk   Disclaimer / Sage Advice All content is educational in nature, but is never intended to be acted upon independent of organised educational and training structures, and under appropriate supervision for your stage of training.  This information is not a suitable substitute for medical advice and requests for medical advice will not be acted upon. Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present.   Music Credit: Streets of Sant Ivo - Mid-Air Machine - Free music archive Sassy Jazzy - La Faena - Free music archive #FOAMed #frcaprimary #frca #Anaesthetics #Anaesthesia  #Pharmacology #primaryFRCA #GasGasGas

Welcome to the final local anaesthetic episode - Peri-neural adjuncts- because we should not forget the medley of mixing options that you could stir into your NRfit cauldron.... although most folks don't. GasGasGas - putting knowledge in your brain! Show notes at: Link incoming  A podcast for the Primary FRCA Exams ———————— Donations to keep the lights on willingly accepted! Dr Gas Lurks on:  BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X FaceBook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk   Disclaimer / Sage Advice All content is educational in nature, but is never intended to be acted upon independent of organised educational and training structures, and under appropriate supervision for your stage of training.  This information is not a suitable substitute for medical advice and requests for medical advice will not be acted upon. Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present.   Music Credit: Streets of Sant Ivo - Mid-Air Machine - Free music archive Sassy Jazzy - La Faena - Free music archive #FOAMed #frcaprimary #frca #Anaesthetics #Anaesthesia  #Pharmacology #primaryFRCA #GasGasGas

Welcome to an experimental episode of GasGasGas - where you get the joys of a quiz after listening to all these episodes on local anaesthetics agents. Let me know if you think it's dry as hell. GasGasGas - putting knowledge in your brain! Show notes at: https://gasgasgas.uk/local-anaesthetic-quiz/ A podcast for the Primary FRCA Exams ———————— Donations to keep the lights on willingly accepted! Dr Gas Lurks on:  BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X FaceBook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk   Disclaimer / Sage Advice All content is educational in nature, but is never intended to be acted upon independent of organised educational and training structures, and under appropriate supervision for your stage of training.  This information is not a suitable substitute for medical advice and requests for medical advice will not be acted upon. Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present.   Music Credit: Streets of Sant Ivo - Mid-Air Machine - Free music archive Sassy Jazzy - La Faena - Free music archive #FOAMed #frcaprimary #frca #Anaesthetics #Anaesthesia  #Pharmacology #primaryFRCA #GasGasGas

Welcome to another essential episode of Gas Gas Gas, where we summarise all the local anaesthetic content we have covered - In order to get you fired up for the most exciting quiz on local anaesthetics you've ever had the pleasure of listening to.   GasGasGas - putting knowledge in your brain! Show notes at: https://gasgasgas.uk/comparing-local-anaesthetics/ A podcast for the Primary FRCA Exams ———————— Donations to keep the lights on willingly accepted! Dr Gas Lurks on:  BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X FaceBook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk   Disclaimer / Sage Advice All content is educational in nature, but is never intended to be acted upon independent of organised educational and training structures, and under appropriate supervision for your stage of training.  This information is not a suitable substitute for medical advice and requests for medical advice will not be acted upon. Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present. #FOAMed #frcaprimary #frca #Anaesthetics #Anaesthesia  #Pharmacology #primaryFRCA #GasGasGas

Welcome to Local Anaesthetic Systemic Toxicity!! (LAST) represents one of the most clinically significant complications in regional anaesthesia practice. This episode explores the pathophysiology, recognition, and management of LAST with particular emphasis on emergency management protocols and risk mitigation strategies. Understanding LAST is crucial for safe regional anaesthesia practice, as it can occur with any local anaesthetic administration and requires immediate, systematic intervention. Show notes at: https://gasgasgas.uk/local-anaesthetic-systemic-toxicity/ A podcast for the Primary FRCA Exams ———————— Donations to keep the lights on willingly accepted! Dr Gas Lurks on:  BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X FaceBook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk   Disclaimer / Sage Advice All content is educational in nature, but is never intended to be acted upon independent of organised educational and training structures, and under appropriate supervision for your stage of training.  This information is not a suitable substitute for medical advice and requests for medical advice will not be acted upon. Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present. #FOAMed #frcaprimary #frca #Anaesthetics #Anaesthesia  #Pharmacology #primaryFRCA #GasGasGas

Welcome to another essential episode of Gas Gas Gas, where we dive deep into the pharmacology that could make or break your FRCA primary exam. Today we're exploring ropivacaine - the local anaesthetic you might not see every day, but absolutely need to understand when bupivacaine is in short supply or when examiners want to test your knowledge of enantiomeric purity and differential motor blockade. Show notes at: https://gasgasgas.uk/ropivacaine/ A podcast for the Primary FRCA Exams ———————— Donations to keep the lights on willingly accepted! Dr Gas Lurks on:  BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X FaceBook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk   Disclaimer / Sage Advice All content is educational in nature, but is never intended to be acted upon independent of organised educational and training structures, and under appropriate supervision for your stage of training.  This information is not a suitable substitute for medical advice and requests for medical advice will not be acted upon. Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present. #FOAMed #frcaprimary #frca #Anaesthetics #Anaesthesia  #Pharmacology #primaryFRCA #GasGasGas

Welcome to lidocaine - the ubiquitous local anaesthetic that's everywhere in clinical practice but comes with some important caveats. Whether you're preparing for your primary FRCA exams or just starting your anaesthesia rotations, understanding lidocaine's extensive clinical applications, antiarrhythmic properties, and the growing role of IV infusions for pain management is essential. Show notes at: https://gasgasgas.uk/lidocaine/ A podcast for the Primary FRCA Exams ———————— Donations to keep the lights on willingly accepted! Dr Gas Lurks on:  BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X FaceBook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk   Disclaimer / Sage Advice All content is educational in nature, but is never intended to be acted upon independent of organised educational and training structures, and under appropriate supervision for your stage of training.  This information is not a suitable substitute for medical advice and requests for medical advice will not be acted upon. Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present. #FOAMed #frcaprimary #frca #Anaesthetics #Anaesthesia  #Pharmacology #primaryFRCA #GasGasGas

Welcome to the Prilocaine episode - the local anaesthetic that's often overshadowed by Bupivacaine but deserves a place in your clinical toolkit. Whether you're preparing for your primary FRCA exams or just starting your anaesthesia rotations, understanding Prilocaine's unique properties will help you tailor anaesthesia to patient and surgery bupivacaine isn't always the answer Show notes at: https://gasgasgas.uk/prilocaine-for-the-frca-primary/  A podcast for the Primary FRCA Exams ———————— Donations to keep the lights on willingly accepted! Dr Gas Lurks on:  BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X FaceBook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk   Disclaimer / Sage Advice All content is educational in nature, but is never intended to be acted upon independent of organised educational and training structures, and under appropriate supervision for your stage of training.  This information is not a suitable substitute for medical advice and requests for medical advice will not be acted upon. Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present. #FOAMed #frcaprimary #frca #Anaesthetics #Anaesthesia  #Pharmacology #primaryFRCA #GasGasGas

If you like a story about extensive testicular traction and hammering shins then this is the episode for you.  This FRCA Primary Podcast episode explores cocaine and the exposure patients have to it in the clinical environment, chiefly courtesy of the ENT surgeons. The episode explores mechanism, side effects, onset, implications, but also the history of spinal anaesthesia and treatment of cocaine toxicity in the A&E department.  Show notes at: https://gasgasgas.uk/episode-32-cocaine-local-anaesthetics-series/ A podcast for the Primary FRCA Exams ———————— Donations to keep the lights on willingly accepted! Dr Gas Lurks on:  BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X FaceBook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk   Disclaimer / Sage Advice All content is educational in nature, but is never intended to be acted upon independent of organised educational and training structures, and under appropriate supervision for your stage of training.  This information is not a suitable substitute for medical advice and requests for medical advice will not be acted upon. Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present. #FOAMed #frcaprimary #frca #Anaesthetics #Anaesthesia  #Pharmacology #primaryFRCA #GasGasGas

This FRCA Primary Podcast episode dives deep into bupivacaine, exploring its friends (additives), mechanism of action, and clinical applications. We'll also cover the key differences between neuronal and cardiac action potentials, and discuss why levobupivacaine has become the preferred choice in many clinical scenarios. Show notes at: https://gasgasgas.uk/primary-frca-podcast-episode-31-bupivacaine-and-friends/ A podcast for the Primary FRCA Exams ———————— Donations to keep the lights on willingly accepted! Dr Gas Lurks on:  BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X FaceBook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk   Disclaimer / Sage Advice All content is educational in nature, but is never intended to be acted upon independent of organised educational and training structures, and under appropriate supervision for your stage of training.  This information is not a suitable substitute for medical advice and requests for medical advice will not be acted upon. Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present. #FOAMed #frcaprimary #frca #Anaesthetics #Anaesthesia  #Pharmacology #primaryFRCA #GasGasGas

This FRCA Primary Podcast episode establishes the scientific foundation you need to understand how Local Anaesthetic drugs work, why they behave differently, and how to use them safely. By the end, you'll understand nerve physiology, sodium channel blockade, drug classification, and the basics of local anaesthetic toxicity. Show notes at: https://gasgasgas.uk/local-anaesthetic-fundamentals-for-the-frca/ A podcast for the Primary FRCA Exams ———————— Donations to keep the lights on willingly accepted! Dr Gas Lurks on:  BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X FaceBook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk   Disclaimer / Sage Advice All content is educational in nature, but is never intended to be acted upon independent of organised educational and training structures, and under appropriate supervision for your stage of training.  This information is not a suitable substitute for medical advice and requests for medical advice will not be acted upon. Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present. #FOAMed #frcaprimary #frca #Anaesthetics #Anaesthesia  #Pharmacology #primaryFRCA #GasGasGas

This FRCA Primary Podcast covers: Opioids are a significant cornerstone of anaesthetic practice, forming part of the triad of anaesthesia with their analgesic properties. We utilize these analgesic properties not just because "surgery hurts," but also because our interventions cause discomfort - laryngoscopy being a prime example. Each opiate has distinct pharmacokinetic and pharmacodynamic properties that make it a better (or worse) choice for individual scenarios. This episode focuses on making sensible comparisons between morphine, fentanyl, alfentanil, and remifentanil - when and where to choose each one. Show notes at: https://gasgasgas.uk/comparing-opioids-for-the-frca-primary/  A  podcast for the Primary FRCA Exams ———————— Donations to keep the lights on willingly accepted! Dr Gas Lurks on:  BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X FaceBook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk   Disclaimer / Sage Advice All content is educational in nature, but is never intended to be acted upon independent of organised educational and training structures, and under appropriate supervision for your stage of training.  This information is not a suitable substitute for medical advice and requests for medical advice will not be acted upon. Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present. #FOAMed #frcaprimary #frca #Anaesthetics #Anaesthesia  #Pharmacology #primaryFRCA #GasGasGas

Remifentanil is an anaesthetist’s dream: ultra-short acting, reliably titratable, and deeply potent. This episode takes a dual-pronged approach—covering both the FRCA-relevant pharmacology of remifentanil and introducing the Minto target-controlled infusion (TCI) model.  Show notes at: https://gasgasgas.uk/remifentanil-and-minto-tci-model/ A  podcast for the Primary FRCA Exams ———————— Donations to keep the lights on willingly accepted! Dr Gas Lurks on:  BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X FaceBook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk   Disclaimer / Sage Advice All content is educational in nature, but is never intended to be acted upon independent of organised educational and training structures, and under appropriate supervision for your stage of training.  This information is not a suitable substitute for medical advice and requests for medical advice will not be acted upon. Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present. #FOAMed #frcaprimary #frca #Anaesthetics #Anaesthesia  #Pharmacology #primaryFRCA #GasGasGas

In this explainer episode of GasGasGas, James delves into the joyful complexities of neuraxial opiate pharmacology. Why do we bother putting opiates into this space at all? What governs their journey, how do they behave once administered, and what clinical pearls can be drawn from their behaviour? This episode follows the journey of a single opioid molecule through the fatty labyrinth of the epidural space, across barriers, and into its final destination: the dorsal horn of the spinal cord. Show notes at: https://gasgasgas.uk/neuraxial-opiate-kinetics-for-the-frca-primary/ A  podcast for the Primary FRCA Exams ———————— Donations to keep the lights on willingly accepted! Dr Gas Lurks on:  BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X FaceBook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk   Disclaimer / Sage Advice All content is educational in nature, but is never intended to be acted upon independent of organised educational and training structures, and under appropriate supervision for your stage of training.  This information is not a suitable substitute for medical advice and requests for medical advice will not be acted upon. Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present. #FOAMed #frcaprimary #frca #Anaesthetics #Anaesthesia  #Pharmacology #primaryFRCA #GasGasGas

In this episode of Gas, Gas, Gas, we dive deep into the pharmacology of diamorphine — also known by its more notorious street name, heroin. Diamorphine is a synthetic diacetylated derivative of morphine, and this episode details its mechanism of action, clinical applications, pharmacokinetics, pharmacodynamics, and side effect profile. The episode is structured to support FRCA Primary revision with an irrelevant clinical anecdote (but sound advice I would argue) and exam-focused clarity.   Show notes at: https://gasgasgas.uk/diamorphine-for-the-frca-primary/  ———————— Donations to keep the lights on willingly accepted! Dr Gas Lurks on:  BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X FaceBook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk ———————— We have a catalogs of Podcast and Vivacast episodes here!  Primary FRCA Podcast Catalog Primary FRCA VivaCast Catalog ———————— #FOAMed #frcaprimary #frca #Anaesthetics #Anaesthesia  #Pharmacology #Physiology A Primary FRCA podcast ———————— Want to have a chat? james@gasgasgas.uk  ———————— Disclaimer / Sage Advice All content is educational in nature, but is never intended to be acted upon independent of organised educational and training structures, and under appropriate supervision for your stage of training.  This information is not a suitable substitute for medical advice and requests for medical advice will not be acted upon. Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present.  

In this episode of GasGasGas, we a plunge into the pharmacology of oxycodone, a potent semi-synthetic opioid analgesic widely used in perioperative and chronic pain settings. Aimed at FRCA Primary candidates and anaesthetic trainees, this episode explores oxycodone's mechanism of action, pharmacokinetics, and pharmacodynamics, as well as its clinical indications, side effect profile, and relevance in anaesthesia and acute pain management. We dissect its action on mu-opioid receptors, compare it to morphine and other opioids, and review evidence regarding oral vs intravenous formulations, metabolism via CYP450 enzymes (notably CYP3A4 and CYP2D6), and implications for renal and hepatic impairment. Key FRCA-focused discussions include its use in multimodal analgesia, potential for respiratory depression, and issues of dependence and controlled drug legislation. Show notes at: https://gasgasgas.uk/oxycodone-frca-primary/ A  podcast for the Primary FRCA Exams ———————— Donations to keep the lights on willingly accepted! Dr Gas Lurks on:  BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X FaceBook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk   Disclaimer / Sage Advice All content is educational in nature, but is never intended to be acted upon independent of organised educational and training structures, and under appropriate supervision for your stage of training.  This information is not a suitable substitute for medical advice and requests for medical advice will not be acted upon. Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present. #FOAMed #frcaprimary #frca #Anaesthetics #Anaesthesia  #Pharmacology #primaryFRCA #GasGasGas