hol+ with Dr. Taz MD | The Future of Medicine is Holistic

Breast cancer screening is often treated as a given. Mammograms are framed as routine, early detection as unquestionably life-saving, and following guidelines as the responsible choice. But what if the full picture is more complicated?In this episode of hol+, Dr. Taz sits down with integrative oncologist and breast surgeon Dr. Jenn Simmons, author of The Smart Woman's Guide to Breast Cancer, to explore what breast cancer screening data actually shows, where common narratives may oversimplify reality, and how statistics can sometimes be misunderstood by both patients and providers.Together, they discuss the difference between screening and diagnostic imaging, why detecting more cancers does not always mean fewer deaths, and how concepts like overdiagnosis and lead-time bias shape our interpretation of outcomes. Dr. Jenn also explains how breast cancer behaves differently from many other cancers, why progression is not always linear, and what tumor markers like ER, PR, HER2, and triple-negative really indicate.The conversation expands beyond imaging into a whole-body view of breast health, touching on inflammation, immune function, metabolic health, toxic burden, stress, and lifestyle as factors that shape cancer risk and recovery. Rather than promoting fear or urgency, this episode focuses on helping listeners understand their bodies, ask better questions, and make informed decisions with clarity.This episode is for anyone who wants a deeper understanding of breast cancer screening, feels overwhelmed by conflicting guidance, or wants to approach breast health with more nuance and less panic.About Dr. Jenn SimmonsDr. Jenn Simmons is an integrative oncologist, breast surgeon, and founder of Real Health MD. She was Philadelphia’s first fellowship-trained breast surgeon and spent nearly two decades leading one of the region’s top breast programs before transitioning into integrative oncology.Drawing from her experience in conventional cancer care and her own health journey, Dr. Simmons now focuses on whole-body approaches to breast health, cancer prevention, and recovery, including metabolic health, inflammation, immune function, lifestyle medicine, and root-cause healing. She is the author of The Smart Woman's Guide to Breast Cancer, a patient-centered resource designed to help women better understand their diagnosis, ask informed questions, and navigate treatment decisions with clarity rather than fear.Order the BookThe Smart Woman's Guide to Breast Cancer Stay Connected:Connect further to Hol+ at https://holplus.co/- Don’t forget to like, subscribe, and hit the notification bell to stay updated on future episodes of hol+.Follow Dr. Jenn SimmonsInstagram: https://www.instagram.com/drjennsimmonsYouTube: https://www.youtube.com/@dr.jennsimmonsWebsite: https://www.jennsimmonsmd.com/Follow Dr. Taz on Instagram: https://www.instagram.com/drtazmd/https://www.instagram.com/liveholplus/Subscribe to the audio podcast: https://holplus.transistor.fm/subscribeSubscribe to the video podcast: https://www.youtube.com/@DrTazMD/podcastsGet your copy of The Hormone Shift: Balance Your Body and Thrive Through Midlife and MenopauseHost & Production TeamHost: Dr. Taz; Produced by ClipGrowth.com (Producer: Pat Gostek)00:00 Swedish trial claim and overdiagnosis framing 00:52 Why this became a part two conversation 03:25 Reframing screening narratives and medical training gaps 04:39 Why Dr. Simmons questions mammograms as a screening tool 06:06 Origins of screening programs and “invitation to screen” bias 07:12 Relative risk vs absolute numbers example (4 vs 5 per 1,000) 08:49 Overdiagnosis explained with a vivid analogy 09:50 Autopsy-study claim and the “microscopic cancer” idea 12:11 Swedish trial claim revisited: more diagnoses, same deaths 13:38 Downstream harms: callbacks, biopsies, overtreatment 15:04 Lead-time bias and survival statistics explained 16:44 Dr. Simmons’ view on the founder’s regret narrative 18:16 Switzerland headline clarified and what actually changed 20:10 Cautionary stories and aggressive cancers discussion 22:07 Why breast cancer does not always progress linearly 24:21 Buckets: DCIS, invasive, inflammatory, receptor types 26:15 Clinical vs subclinical disease approach 28:25 Long-term tradeoffs and “forgotten woman” after treatment 32:15 What ER PR HER2 mean biologically and system incentives 35:33 Testosterone discussion and prevention claim presented 42:15 Hormones after breast cancer and the 4-year “reintroduction” idea 44:29 Triple negative: environment, toxicity, immune system focus 49:19 What to do next: pause, exceptions, whole-body workup 52:32 Prevention and breast health approach begins 53:24 At-home tears test explanation (as discussed) 56:24 Detox basics and why sweating is emphasized 59:34 Imaging preferences for screening and what to do if limited access

OCD is often misunderstood as being about cleanliness, checking, or perfectionism. In this episode, Dr. Taz sits down with therapist and author Melissa Mose, LMFT, to unpack why OCD is frequently misdiagnosed for over a decade and what’s really happening beneath the surface of obsessions and compulsions. Melissa’s book Internal Family Systems Therapy for OCD bridges compassionate parts-based work with proven science to offer a richer path to lasting change.Using clear science and compassionate explanations, this conversation explores how OCD hijacks the brain through a cycle of alarm and relief, why reassurance and family accommodation can quietly reinforce symptoms, and what actually works in treatment. Melissa breaks down why talk therapy alone often fails OCD, how Exposure and Response Prevention (ERP) retrains the nervous system, and how Internal Family Systems (IFS) adds depth, self-compassion, and relational healing to recovery.In this hol+ conversation, Dr. Taz sits down with therapist, educator, and author Melissa Mose, LMFT, to unpack what OCD really is and why it often goes undiagnosed for over a decade. Melissa shares why OCD disguises itself as “just anxiety,” how well-meaning reassurance can quietly reinforce the disorder, and why many people spend years in talk therapy without real relief.Using clear science and compassionate language, this episode explores how OCD operates through a cycle of alarm and relief, why the brain learns to depend on compulsions, and how Exposure and Response Prevention (ERP) helps retrain the nervous system. Melissa also explains how Internal Family Systems (IFS) adds a relational, self-compassionate layer to treatment, helping people work with their inner world instead of battling it.This conversation also looks at the bigger picture. OCD does not exist in isolation. Dr. Taz and Melissa explore how neuroinflammation, PANS and PANDAS, hormonal shifts, trauma, ADHD, eating disorders, and chronic stress can overlap with or intensify OCD symptoms. They discuss why intrusive thoughts can be disturbing and taboo, why intolerance of uncertainty sits at the core of OCD, and how relationships and intimacy are often quietly impacted.From shame and self-blame to clarity and support, this episode offers a grounded reframe of OCD as a treatable condition rooted in brain-body patterns, not personal failure. Whether you are seeking help for yourself, supporting someone you love, or trying to understand OCD beyond the stereotypes, this conversation replaces fear with understanding and helplessness with practical pathways forward.Dr. Taz and Melissa Mose, LMFT discuss: Why OCD often goes undiagnosed for 11 to 17 years How reassurance and family accommodation make OCD worse The obsession-compulsion cycle and why it gets reinforced Why talk therapy alone often fails OCD What ERP actually does to retrain the brain How Internal Family Systems supports compassion and healing The role of uncertainty intolerance in OCD How OCD affects families, partners, and intimacy Neuroinflammation, PANS, PANDAS, hormones, and symptom flares Why intrusive thoughts do not define who you areAbout Melissa Mose, LMFT Melissa Mose is a licensed marriage and family therapist, educator, and specialist in the treatment of obsessive-compulsive disorder. With over 30 years of clinical experience, she works with individuals and families navigating OCD and anxiety, and trains clinicians in evidence-based treatment approaches. Melissa integrates Exposure and Response Prevention with Internal Family Systems to support deep, sustainable change that goes beyond symptom management. Melissa is the author of Internal Family Systems Therapy for OCD: A Clinician’s Guide, a resource designed to help therapists bring compassion, parts-based awareness, and relational healing into gold-standard OCD treatment.Stay Connected:Connect further to Hol+ at https://holplus.co/- Don’t forget to like, subscribe, and hit the notification bell to stay updated on future episodes of hol+.Follow Melissa Mose, LMFT Learn more about Melissa’s work: https://melissamosemft.comInstagram: https://www.instagram.com/melissamosemftFollow Dr. Taz on Instagram: https://www.instagram.com/drtazmd/https://www.instagram.com/liveholplus/Subscribe to the audio podcast: https://holplus.transistor.fm/subscribeSubscribe to the video podcast: https://www.youtube.com/@DrTazMD/podcastsGet your copy of The Hormone Shift: Balance Your Body and Thrive Through Midlife and MenopauseHost & Production TeamHost: Dr. Taz; Produced by ClipGrowth.com (Producer: Pat Gostek)

Many women reach their 30s and suddenly feel an invisible pressure set in. The clock gets louder. The messaging gets scarier. And fertility, something that once felt distant or optional, becomes charged with fear, urgency, and self-blame.This episode is for anyone who has ever wondered if they waited too long, if their body is betraying them, or if turning 35 means everything has suddenly changed.This is not a failure of timing.This is not a lack of effort.And it is not a fertility cliff.In this hol+ conversation, Dr. Taz sits down with double board-certified reproductive endocrinologist and infertility specialist Dr. Lucky Sekhon to dismantle one of the most anxiety-producing myths in women’s health: that fertility suddenly collapses at 35.Dr. Lucky explains why fertility is a continuum, not a deadline, and why the panic surrounding age often does more harm than the biology itself. Using clear science and compassionate language, she breaks down the difference between egg quantity and egg quality, why egg quality cannot be directly tested, and what actually changes as women age.This episode explores why fertility struggles are increasing worldwide, even among young women, and how factors like insulin resistance, PCOS, endometriosis, inflammation, environmental toxins, and chronic stress quietly shape reproductive health long before pregnancy becomes a goal.Dr. Taz and Dr. Lucky also reframe painful and irregular periods as vital signs that should never be ignored, explain why many fertility diagnoses remain unclear, and clarify how treatments like IUI and IVF work not because the body is broken, but because human reproduction is naturally inefficient.From fear-based fertility messaging to evidence-based clarity, this conversation offers a grounding reset. If you are trying to get pregnant, thinking about egg freezing, navigating fertility anxiety, or simply want to understand your body better, this episode replaces panic with perspective and urgency with informed choice.Dr. Taz and Dr. Lucky Sekhon discuss:• Why fertility does not suddenly end at 35• The difference between egg count and egg quality• Why egg quality cannot be directly tested• The real drivers behind declining fertility rates• PCOS, endometriosis, and insulin resistance as fertility blockers• Why painful or irregular periods are red flags• What fertility treatments actually improve and what they cannot• How to approach pregnancy with clarity instead of fearAbout Dr. Lucky SekhonDr. Lucky Sekhon is a double board-certified reproductive endocrinologist, infertility specialist, and OB/GYN based in New York City. She is widely recognized for her compassionate, evidence-based approach to fertility care and her ability to translate complex reproductive science into language women can actually understand.Dr. Lucky is the author of The Lucky Egg: Understanding Your Fertility and How to Get Pregnant Now, a practical and empowering guide designed to help individuals and couples navigate fertility decisions with confidence, clarity, and realism. Her work focuses on demystifying fertility testing, treatment options, and the emotional toll of trying to conceive.In addition to her clinical work, Dr. Lucky is a trusted educator across social media and digital platforms, where she helps women move beyond fear-based fertility narratives and make informed choices aligned with their life goals.Order the BookThe Lucky Egg: Understanding Your Fertility and How to Get Pregnant NowStay Connected:Connect further to Hol+ at https://holplus.co/- Don’t forget to like, subscribe, and hit the notification bell to stay updated on future episodes of hol+.Follow Dr. Lucky SekhonInstagram: https://www.instagram.com/lucky.sekhonWebsite: https://theluckyegg.com/Follow Dr. Taz on Instagram: https://www.instagram.com/drtazmd/https://www.instagram.com/liveholplus/Subscribe to the audio podcast: https://holplus.transistor.fm/subscribeSubscribe to the video podcast: https://www.youtube.com/@DrTazMD/podcastsGet your copy of The Hormone Shift: Balance Your Body and Thrive Through Midlife and MenopauseHost & Production TeamHost: Dr. Taz; Produced by ClipGrowth.com (Producer: Pat Gostek)

Many women hit midlife and feel something they cannot name. They are still doing the right things, eating well, exercising consistently, showing up for everyone, yet life suddenly feels harder and less familiar. Age Like a Girl gives language to this experience and explains why it is not a failure, but a shift happening beneath the surface.This is not a motivation problem.This is not a discipline issue.And it is not “all in your head."In this hol+ conversation, Dr. Taz sits down with New York Times bestselling author and leading voice in women’s health Dr. Mindy Pelz, host of the hit podcast The Resetter Podcast, to explore the core message behind Age Like a Girl: menopause is not a decline, it is a biologically wired reinvention.Instead of treating perimenopause and menopause as a crisis to manage, Dr. Mindy reframes the transition as a neurochemical and cognitive remodel designed to make women more focused, emotionally resilient, and aligned with who they truly are. She breaks down why modern life often clashes with this primal design, and why brain fog, mood shifts, and emotional intensity are not random symptoms, but signals that the brain is asking for a new way of living.This episode explores why women can feel anxious, disconnected, or unlike themselves even when they are “doing everything right,” and how metabolism, stress chemistry, and neurotransmitters shape mood, clarity, and identity. Dr. Taz and Dr. Mindy discuss why many women initiate big life and relationship changes after 40, why community and connection become essential, and why reinvention is not a midlife crisis, but biology.From perimenopause into postmenopause, this conversation reframes aging as an awakening. Not the end of youth, but the return of clarity, boundaries, and self-trust. If you have ever felt dismissed, confused, or afraid that something is wrong with you, this episode offers a validating and hopeful roadmap forward.Dr. Taz and Dr. Mindy Pelz discuss: • The core message of Age Like a Girl and why it reframes menopause • Why the female brain is biologically wired for reinvention after 40 • Brain fog and mood shifts as signals of a cognitive remodel • How modern life clashes with primal biology • Why women often make major life decisions in midlife • The role of neurotransmitters in clarity, calm, and confidence • Why community and deep connection matter more than ever • How to reclaim vitality without another exhausting checklistAbout Dr. Mindy PelzDr. Mindy Pelz is a New York Times bestselling author, visionary educator, and trailblazer in the field of women’s health and hormone science. With over two decades of experience, she’s built a global movement to help women understand the power of their bodies at every stage of life. Her bestselling books, including Fast Like a Girl, The Menopause Reset, and Eat Like a Girl, have helped millions of women use fasting, nutrition, and lifestyle shifts to balance hormones, boost energy, and take back control of their health. Her newest release book, Age Like a Girl, redefines what it means to grow older as a woman.Rooted in the latest science and rich in personal story, the book challenges outdated narratives about menopause and aging offering instead a roadmap for awakening. Dr. Mindy shows women how to use the neurochemical shifts of midlife as a launchpad for purpose, leadership, and bold reinvention. Dr. Mindy’s Resetter Podcast consistently ranks among Apple’s top U.S. science shows, with guests ranging from LeAnn Rimes and Rachel Hollis to Dr. Rangan Chatterjee. Her YouTube channel has surpassed 110 million views, and her teachings have reached hundreds of thousands through workshops, online programs, and live events.Order the book: Age Like a Girl Stay Connected:Connect further to Hol+ at https://holplus.co/- Don’t forget to like, subscribe, and hit the notification bell to stay updated on future episodes of hol+.Follow Dr. Mindy PelzInstagram: https://www.instagram.com/dr.mindypelz/Website: https://drmindypelz.com/ Podcast: The Resetter PodcastFollow Dr. Taz on Instagram: https://www.instagram.com/drtazmd/https://www.instagram.com/liveholplus/Subscribe to the audio podcast: https://holplus.transistor.fm/subscribeSubscribe to the video podcast: https://www.youtube.com/@DrTazMD/podcastsGet your copy of The Hormone Shift: Balance Your Body and Thrive Through Midlife and MenopauseHost & Production TeamHost: Dr. Taz; Produced by ClipGrowth.com (Producer: Pat Gostek)

What if the real question isn’t just how to live longer, but why so many people are living longer and healthier lives on paper, yet feel depleted, inflamed, disconnected, or cognitively foggy in daily life?In this solo episode, Dr. Taz reframes what longevity really means and why healthy aging has far less to do with chasing more years and far more to do with protecting cellular health, vitality, and resilience across decades. She explains why humans are living longer than ever before, yet not necessarily living better, and how focusing only on disease management or biohacking trends misses the real drivers of aging.You’ll learn why longevity is not defined by a number, but by biological age, health span, and cellular aging, and how inflammation, metabolic dysfunction, gut imbalance, nervous system stress, emotional disconnection, and loss of community quietly accelerate aging long before symptoms become diagnoses.This episode reframes longevity as a full body system, not a supplement stack or a protocol. One that integrates physical health, brain function, emotional regulation, spirituality, and community. When these systems fall out of sync, aging speeds up. When they are supported together, living longer becomes living with clarity, strength, and purpose.Dr. Taz shares: • What longevity actually means and why lifespan and health span are not the same • Why humans are living longer but not necessarily healthier • How cellular aging, inflammation, and metabolic stress drive chronic disease • Why diet quality, gut health, liver function, movement, sleep, and nervous system balance matter more than biohacking • How cognitive reserve, dopamine regulation, and emotional health protect the aging brain • Why community and spirituality are overlooked but essential pillars of healthy aging • Where peptides, hormones, and modern longevity tools fit and where they don’t • How to build a longevity plan that is realistic, accessible, and sustainableWhether you’re thinking about how to live longer, worried about aging faster than you should, or simply want to protect your health span as you move through midlife and beyond, this episode offers a grounded, integrative roadmap.Longevity is not about optimizing harder. It’s about supporting the systems that keep you well, year after year.Stay Connected:Connect further to Hol+ at https://holplus.co/- Don’t forget to like, subscribe, and hit the notification bell to stay updated on future episodes of hol+.Follow Dr. Taz on Instagram: https://www.instagram.com/drtazmd/https://www.instagram.com/liveholplus/Subscribe to the audio podcast: https://holplus.transistor.fm/subscribeSubscribe to the video podcast: https://www.youtube.com/@DrTazMD/podcastsGet your copy of The Hormone Shift: Balance Your Body and Thrive Through Midlife and MenopauseHost & Production TeamHost: Dr. Taz; Produced by ClipGrowth.com (Producer: Pat Gostek)Chapters00:00 Longevity is not about more years00:50 Are humans really living longer01:49 The global aging reality03:31 Why aging became something to fear05:17 Aging on a spectrum, not a number06:07 The hidden disease burden of aging08:31 Cellular aging explained09:45 Why biohacking misses the foundation11:10 The five-body approach to longevity13:10 Community, emotion, and aging14:05 Diet, inflammation, and cellular health16:19 Medications, gut health, and aging16:49 Fasting, calories, and longevity18:52 What eating for longevity actually means19:39 Movement and aging well21:35 Sleep, repair, and brain health22:50 Dementia, cognitive reserve, and prevention24:20 Dopamine, emotion, and brain aging26:49 Spirituality, community, and vitality30:05 Peptides, hormones, and future medicine31:58 A new vision for positive aging32:48 Longevity is built day by day (00:00) - Longevity is not about more years (00:50) - Are humans really living longer (01:49) - The global aging reality (03:31) - Why aging became something to fear (05:17) - Aging on a spectrum, not a number (06:07) - The hidden disease burden of aging (08:31) - Cellular aging explained (09:45) - Why biohacking misses the foundation (11:10) - The five-body approach to longevity (13:10) - Community, emotion, and aging (14:05) - Diet, inflammation, and cellular health (16:19) - Medications, gut health, and aging (16:49) - Fasting, calories, and longevity (18:52) - What eating for longevity actually means (19:39) - Movement and aging well (21:35) - Sleep, repair, and brain health (22:50) - Dementia, cognitive reserve, and prevention (24:20) - Dopamine, emotion, and brain aging (26:49) - Spirituality, community, and vitality (30:05) - Peptides, hormones, and future medicine (31:58) - A new vision for positive aging (32:48) - Longevity is built day by day

Fertility, motherhood, and grief are rarely experienced in isolation. They overlap, compound, and quietly reshape how a woman sees herself, her body, and her future.Many women move through loss while still being expected to function. They carry grief while building families. They navigate pregnancy, postpartum, and fertility decisions while holding careers, relationships, and public identities together. From the outside, it can look composed. Inside, it often feels fragile, confusing, and deeply human.This is not failure.This is not weakness.And it is not something that needs to be fixed.In this hol+ conversation, Dr. Taz sits down with Whitney Port for an honest, grounding conversation about motherhood without the myth, and finding peace after profound loss. Whitney shares what unfolded after The Hills, including the loss of her father, who was also her business partner, and how grief reshaped her identity, marriage, and mental health during a pivotal season of life.Together, they explore the realities that are often softened or skipped entirely. Pregnancy that does not feel joyful. Postpartum that feels disorienting. Breastfeeding struggles that take a real toll on mental health. And the invisible pressure women carry to do motherhood and fertility “the right way.”Whitney also opens up about her fertility journey, including recurrent miscarriage, IVF, surrogacy, and failed transfers. She speaks candidly about the emotional spiral that can happen when you are someone used to achieving goals, but suddenly face something you cannot control. Rather than centering the story on struggle alone, this conversation focuses on what helped her find steadier ground: learning to stop future-spiraling, returning to the present, and holding gratitude alongside grief.This episode is a reminder that healing does not mean bypassing pain. It means allowing space for it, while slowly reconnecting to meaning, relationships, and self-trust. It reframes fertility and motherhood not as tests of worth or discipline, but as deeply relational, emotional, and embodied experiences.Dr. Taz and Whitney Port discuss: • Life after The Hills and the identity shift that followed • Losing a parent and navigating grief while building a family • Motherhood without the myth of constant joy • Pregnancy, postpartum, and mental health honesty • Breastfeeding pressure, pumping, and maternal burnout • Fertility, IVF, surrogacy, and the emotional weight of uncertainty • Why high-achieving women struggle most with loss of control • How to stop future-spiraling and return to the present • Sharing your story publicly while protecting what is sacredAbout Whitney PortWhitney Port is a television personality, entrepreneur, podcast host, and creative consultant. Known for starring on The Hills and The City, she now uses her platform to speak openly about grief, anxiety, fertility, body image, and modern motherhood, helping women feel less alone in experiences that are often hidden.Stay Connected:Connect further to Hol+ at https://holplus.co/- Don’t forget to like, subscribe, and hit the notification bell to stay updated on future episodes of hol+.Follow Whitney Port:Instagram: https://www.instagram.com/whitneyeveportTikTok: https://www.tiktok.com/@whitneyportWebsite: https://whitneyport.com/Podcast: With WhitFollow Dr. Taz on Instagram: https://www.instagram.com/drtazmd/https://www.instagram.com/liveholplus/Subscribe to the audio podcast: https://holplus.transistor.fm/subscribeSubscribe to the video podcast: https://www.youtube.com/@DrTazMD/podcastsGet your copy of The Hormone Shift: Balance Your Body and Thrive Through Midlife and MenopauseHost & Production TeamHost: Dr. Taz; Produced by ClipGrowth.com (Producer: Pat Gostek) (00:00) - Grief after dad’s diagnosis and loss (00:30) - Dr. Taz introduces Whitney Port (01:30) - Pregnancy was not “the best time” (02:00) - Fertility pressure, self-blame, finding the right team (02:30) - Dr. Taz fan-girl moment and why Whitney’s story matters (04:30) - Reality TV then vs now (06:30) - Who Whitney is beyond the show (08:00) - Losing control of your narrative (editing + portrayal) (10:15) - The gifts of the show and creative platform (11:30) - Dad’s illness, grief, identity shift (13:30) - “I Love My Baby, But…” and being vulnerable on YouTube (16:00) - Marriage, grief fog, and coping (18:00) - Breastfeeding, pumping, mastitis, mental health (21:00) - What we’re not telling new moms (trust + noise) (23:00) - Body image, female bodies, and acceptance (27:30) - Fertility journey begins: miscarriage cycle (29:30) - Surrogacy conversation and failed transfers (32:00) - Age, hope, and continuing the journey (33:30) - Shame, grief, staying sane, gratitude shift (37:30) - Finding the right doctor and the lab factor (42:30) - Preparing physically and emotionally this time (44:00) - Privacy boundaries in public life (46:00) - Advice: purpose, staying in your lane (50:30) - Businesses, creative consulting, entrepreneurship (56:30) - What makes you hol + where to follow

What if the fatigue, stubborn weight changes, brain fog, inflammation, or burnout you’re experiencing isn’t a failure of willpower, but a signal that your metabolism is under strain? In this solo episode, Dr. Taz unpacks what metabolic health actually means in the age of GLP-1 medications. She explains why weight loss alone is not the same as healing, and how focusing only on the scale can quietly erode muscle, gut function, hormonal balance, cellular energy, and nervous system resilience.You’ll learn why so many people lose weight but still feel exhausted, inflamed, anxious, or disconnected from their bodies. Dr. Taz breaks down the six core metabolic engines that regulate energy, fat storage, blood sugar, hormones, stress response, and longevity, and why ignoring even one of them can stall long-term health.This episode reframes metabolism as a full body system. One that includes the gut microbiome, hormone signaling, mitochondrial function, liver detoxification, muscle health, and the nervous system. When these systems fall out of sync, weight becomes a symptom, not the root issue.Dr. Taz shares: • Why GLP-1 medications support weight loss but do not repair metabolic dysfunction • How up to 25% of weight lost on GLP-1s can come from muscle, impacting long-term health and longevity • Why the gut is the foundation of metabolic health and how digestion, bile flow, and microbiome balance shape hormones and inflammation • How hormone shifts, especially in midlife, can rapidly disrupt blood sugar, cholesterol, energy, and weight • The role of cellular and mitochondrial health in fatigue, brain fog, and metabolic slowdown • Why liver function is central to detoxification, fat metabolism, and insulin regulation • How stress and nervous system dysregulation can drive cravings, poor sleep, and metabolic instability • How to identify which metabolic engine needs attention first so your plan stays targeted and sustainableWhether you’re currently on a GLP-1, considering one, struggling after coming off, or simply want to build metabolic health that lasts for decades, this episode offers a grounded, integrative roadmap. You don’t need to chase trends or stack solutions. You need to understand the system you’re living in.You may not control every variable that shaped your metabolism, but you can change how it functions moving forward.Stay Connected:Connect further to Hol+ at https://holplus.co/- Don’t forget to like, subscribe, and hit the notification bell to stay updated on future episodes of hol+.Follow Dr. Taz on Instagram: https://www.instagram.com/drtazmd/https://www.instagram.com/liveholplus/Subscribe to the audio podcast: https://holplus.transistor.fm/subscribeSubscribe to the video podcast: https://www.youtube.com/@DrTazMD/podcastsGet your copy of The Hormone Shift: Balance Your Body and Thrive Through Midlife and MenopauseHost & Production TeamHost: Dr. Taz; Produced by ClipGrowth.com (Producer: Pat Gostek)

Many women describe a pattern they are never able to explain. They eat well, exercise consistently, and follow every recommendation they are given. Yet their weight fluctuates, their mood shifts unpredictably, and their focus disappears for weeks at a time. Anxiety creeps in. Depression settles quietly. Brain fog becomes normal. And eventually, shame takes over.This is not a motivation problem.This is not a discipline issue.And it is not “all in your head.”In this hol+ conversation, Dr. Taz sits down with reproductive psychiatrist Dr. Sarah Oreck to reveal why PCOS is not just a hormonal or reproductive condition, but a whole-body mental health story that has been overlooked for decades.Instead of viewing PCOS through isolated symptoms like irregular cycles, acne, or fertility struggles, Dr. Oreck explains how insulin resistance, inflammation, cortisol dysregulation, and androgen shifts directly affect brain chemistry, cognition, emotional regulation, and stress tolerance. She breaks down why women with PCOS experience significantly higher rates of anxiety, depression, brain fog, and eating disorders, even when routine labs appear normal.This episode explores how blood sugar instability alters neurotransmitter production, why inflammation may be a core driver of mood disorders, and how chronic stress and cortisol overload reshape the nervous system over time. Dr. Taz and Dr. Oreck also examine the role of medical gaslighting, delayed diagnosis, and the psychological toll of being told symptoms are imagined, exaggerated, or self-inflicted.From adolescence through fertility journeys, pregnancy, postpartum, and perimenopause, this conversation reframes PCOS as a condition that affects the brain, gut, metabolism, and nervous system together, not in isolation. It highlights why symptom masking often fails, why talk therapy alone is not enough during hormonal dysregulation, and why true healing requires integrated, compassionate care.You will learn why weight swings are not about willpower, why mood changes often track with insulin and cortisol rather than character, how gut health and microbiome shifts influence cognition, and what it means to become hormone-literate early, for yourself and for your children.Together, Dr. Taz and Dr. Oreck offer a clear, validating roadmap for anyone who has felt dismissed, confused, or trapped in a body that will not respond the way it is supposed to.Dr. Taz and Dr. Sarah Oreck discuss: • Why PCOS has a major mental health component that is rarely addressed • How insulin resistance and blood sugar swings impact mood and cognition • The link between inflammation and anxiety, depression, and brain fog • Why cortisol and chronic stress intensify PCOS symptoms • How medical gaslighting delays diagnosis and fuels shame • Why fertility journeys often uncover long-missed PCOS patterns • The connection between PCOS and eating disorders like bulimia • How gut health and microbiome shifts affect brain function • Why birth control can help some women and worsen symptoms for others • The importance of hormone literacy across the lifespan • How to advocate for yourself when symptoms are dismissed • Why healing requires integrated care, not isolated fixesAbout Dr. Sarah Oreck Dr. Sarah Oreck is a reproductive psychiatrist and the founder of Mavida Health. She specializes in the intersection of female reproductive hormones and mental health, with a focus on conditions like PCOS, fertility-related mood disorders, pregnancy, and postpartum mental health. Through clinical care, education, and community building, she works to close the gap between psychiatry, endocrinology, and whole-person medicine.Stay Connected:Connect further to Hol+ at https://holplus.co/- Don’t forget to like, subscribe, and hit the notification bell to stay updated on future episodes of hol+.Follow Dr. Sarah OreckInstagram: https://www.instagram.com/sarahoreckmdWebsite: https://www.sarahoreckmd.com/ & https://mavidahealth.com/ Follow Dr. Taz on Instagram: https://www.instagram.com/drtazmd/https://www.instagram.com/liveholplus/Subscribe to the audio podcast: https://holplus.transistor.fm/subscribeSubscribe to the video podcast: https://www.youtube.com/@DrTazMD/podcastsGet your copy of The Hormone Shift: Balance Your Body and Thrive Through Midlife and MenopauseHost & Production TeamHost: Dr. Taz; Produced by ClipGrowth.com (Producer: Pat Gostek) (00:00) - Doing everything right but nothing changes (00:18) - Shame and medical gaslighting (00:37) - PCOS as a mental health story (01:16) - Inflammation and brain chemistry (02:00) - Focus, memory, emotions, and PCOS (04:21) - Origin story: hormones and gaslighting (06:11) - Why PCOS is missed (07:52) - PCOS and depression/anxiety rates (09:22) - Why fertility journeys reveal PCOS (11:30) - Labs and patterns clinicians ignore (12:59) - Diagnosis criteria explained (14:57) - Blood sugar swings and mood (15:56) - Insulin resistance and cognition (18:18) - Cortisol, stress, and PCOS (20:51) - Pregnancy exposure and cortisol (27:11) - Why we need screening tools (30:49) - Supplements that may help (32:15) - Microbiome and brain fog (44:31) - Rehearsing your story with doctors (46:10) - PCOS and bulimia connection (49:42) - Become hormone literate early

What if the anxiety, burnout, inflammation, or exhaustion you carry didn’t begin with you?In this solo episode, Dr. Taz explores the emerging science behind generational trauma and how stress, fear, and survival patterns can be passed down biologically through mitochondrial DNA, the nervous system, and hormonal pathways. She explains why some people struggle with symptoms that don’t resolve despite doing everything right, and how ancestral trauma may be quietly shaping inflammation, cortisol levels, emotional regulation, and energy production across generations.You will learn how trauma can alter mitochondrial function, disrupt the HPA axis, and create inherited patterns of hypervigilance, anxiety, burnout, and chronic disease. Dr. Taz introduces her five body map framework, physical, mental, emotional, spiritual, and community, to help you understand where inherited trauma may be showing up and how healing becomes possible when all layers are addressed.Dr. Taz shares: • How trauma can be transmitted biologically through mitochondrial DNA passed down the maternal line • Why chronic inflammation, insulin resistance, and cortisol dysregulation often appear in families with histories of displacement, silence, or survival stress • The signs of inherited nervous system patterns, including hypervigilance, fear based thinking, emotional suppression, and burnout that starts early • How ancestral trauma affects hormones, energy production, mental health, and emotional regulation • Why family secrets, shame, and silence can destabilize the entire family ecosystem and show up as disease • The five body map approach to screening generational trauma across physical, mental, emotional, spiritual, and community layers • Practical ways to begin healing, including nervous system regulation, storytelling, somatic release, mitochondrial support, and restoring safe connection within familiesWhether you are dealing with unexplained symptoms, chronic stress, emotional patterns that seem bigger than your life experience, or simply want to understand your family’s health history more deeply, this episode offers a new lens on healing. You may inherit biology, but you can change how it is expressed and what gets passed forward.Stay Connected:Connect further to Hol+ at https://holplus.co/- Don’t forget to like, subscribe, and hit the notification bell to stay updated on future episodes of hol+.Follow Dr. Taz on Instagram: https://www.instagram.com/drtazmd/https://www.instagram.com/liveholplus/Subscribe to the audio podcast: https://holplus.transistor.fm/subscribeSubscribe to the video podcast: https://www.youtube.com/@DrTazMD/podcastsGet your copy of The Hormone Shift: Balance Your Body and Thrive Through Midlife and MenopauseHost & Production TeamHost: Dr. Taz; Produced by ClipGrowth.com (Producer: Pat Gostek) (00:00) - Hi everyone, it's Dr. Taz. Before we get into today's episode, I just wanna pause and say thank you. Your messages, your shares, your stories are, the reason we make Whole Plus every conversation here is about connecting the science, the intuition, and everyday life together so you can feel more like yourself. (00:00) - if you haven't already hit that subscribe or follow button, it helps us reach more people who need this. All right, let's begin. What if the pain you [00:00:30] carry didn't start with you? Science now shows that trauma can be passed through generations, not just through stories or behaviors, but through biological changes in the body itself. (00:00) - this episode, we're exploring the connection between ancestral trauma and mitochondrial DNA and how your body might still be echoing the stress, the fear, or the survival patterns of your lineage. The gift of being in practice for over 16 years and seeing, I don't know how [00:01:00] many patients, I think collectively as, uh, a series of whole plus clinics were at 60, 70,000. (00:00) - the gift of seeing a patient day in and day out and following them through their journey. Allows us as providers a lot of time to think, observe, learn, and listen. And one of the things that has always confused me until recently is why some people have symptoms or have issues without any explanation.[00:01:30] (00:00) - done all the right things. They're following the diet, they're exercising, they are doing all the things they're supposed to do. They've got those wellness routines down, red, light, blue, light, you name it, they're doing it, but they're still not well. And while I could have a conversation with all of you about chemistry and biology and physiology, here's what maturity and time has taught me. (00:00) - healing and being well doesn't exist on [00:02:00] one plane. It's not just about the numbers and the data. It's actually a whole lot more, so much more that it may even be linked to your generational trauma. Now, bear with me for a second. Please don't roll your eyes and change the channel or flip the screen. (00:00) - is important information and we are just beginning to understand what all of this means and how it's all connected. I've had many opportunities to observe [00:02:30] this. Some of them begin right in our home. I have watched as the women in our family have a very similar look in their eye demeanor way of talking tone. (00:00) - name it. Some of it we could explain away. My mom was an immigrant, came here at a very young age, 17, 18, 19 years old, had an arranged marriage. She had, I thought, the insecurity of being an immigrant, of being somebody in a new [00:03:00] country without a community. And I always explained away her inability or fear. (00:00) - of in terms of taking action or taking next steps as a part of that story, the immigrant story, right? I, I can't imagine what so many immigrants go through to get here and then to build a life in a family of their own, leaving behind mothers and fathers, brothers and sisters, huge families. So I explained her story away that way. (00:00) - then there [00:03:30] was me and I grew up, as I've shared sometimes in a slightly chaotic, dysfunctional childhood home, and I don't wanna get into all of those details, but I had that same glimmer of fear and insecurity that I saw in my mom. But let's fast forward to my daughter all these years later, growing up in a pampered home with a father that dotes on her. (00:00) - we doted on her even a bit too much, but regardless, had all the comforts and the [00:04:00] security that anybody externally could provide. But guess what? The same glimmer, that same sparkle, that same sort of tone. Something, I can't describe it, where there's fear...

Postpartum is not just a recovery phase, it is one of the biggest full body transitions a woman will ever go through. In this episode, Dr. Taz breaks down what actually happens in the fourth trimester, from the steep drop in estrogen and progesterone to fluid shifts, tissue dryness, gut slowdown, metabolic changes, and the mental and emotional load that can follow. You will learn why so many women feel unprepared after birth, why the six week bounce back expectation is unrealistic, and how older systems like Chinese medicine and Ayurveda approached postpartum as a sacred 40 to 100 day window of restoration.Dr. Taz shares: • Why postpartum can feel so destabilizing: the hormone crash, nervous system strain, and energy depletion most women are never taught about • The hidden physical shifts after delivery, including swelling and fluid volume changes that can take months to fully regulate • Why skin, hair, and vaginal dryness are common postpartum, and how this can affect libido, confidence, and self perception • How breastfeeding changes hormones, including oxytocin’s calming effect and its relationship with cortisol and mood • Why weight loss varies dramatically postpartum, and how insulin sensitivity, blood sugar history, PCOS, and metabolic factors change the timeline • The gut changes no one talks about: slower motility, constipation, reflux, and why progesterone shifts play a role • The fourth trimester frameworks from Chinese medicine and Ayurveda: rest, warming foods, nourishment, massage, acupuncture, herbs, and community care • A modern 100 day postpartum plan that starts in the third trimester with nutrient optimization, thyroid and blood sugar support, gut health, and a real support circleWhether you are newly postpartum, preparing for birth, or supporting someone in those early months, this episode gives you a clear, practical roadmap to protect energy, reduce depletion, and recover in a way that helps you feel like yourself again.Stay Connected:Connect further to Hol+ at https://holplus.co/- Don’t forget to like, subscribe, and hit the notification bell to stay updated on future episodes of hol+.Follow Dr. Taz on Instagram: https://www.instagram.com/drtazmd/https://www.instagram.com/liveholplus/Subscribe to the audio podcast: https://holplus.transistor.fm/subscribeSubscribe to the video podcast: https://www.youtube.com/@DrTazMD/podcastsGet your copy of The Hormone Shift: Balance Your Body and Thrive Through Midlife and MenopauseHost & Production TeamHost: Dr. Taz; Produced by ClipGrowth.com (Producer: Pat Gostek)

Many people today describe a pattern they cannot explain. Life feels manageable until something unexpected happens at work or home, then the body suddenly shuts down. The mind spins, energy collapses, irritability rises, and the only thing that feels safe is withdrawing into the couch, the phone, or Netflix. This is not laziness or burnout. This is functional freeze. In this hol+ conversation, Dr. Taz sits down with environmental and root cause medicine expert Dr. Jessica Peatross (Dr. Jess) to reveal why so many people experience chronic fatigue, anxiety, weight gain, histamine reactions, food sensitivities and unexplained inflammation even when routine labs look normal.Instead of chasing symptoms or isolated toxins, Dr. Jess explains how a dysregulated nervous system alters detox, hormones, digestion, immunity and gene expression. She breaks down how trauma, mold exposure, hidden infections, parasites and environmental chemicals overload the body when the vagus nerve is stuck in fight, flight or freeze. And she shows why healing is impossible when the body does not feel safe.From childhood trauma and dorsal vagal shutdown to blocked drainage pathways, cytokine storms, reactivated viruses and misdiagnosed environmental illness, this episode reframes chronic symptoms through a lens of nervous system physiology, not personal weakness or aging.You will learn what functional freeze looks like, why detox often makes people worse, how to identify nervous system dysregulation, and the steps Dr. Jess uses to help patients regulate, open pathways and finally begin to heal. Together, Dr. Taz and Dr. Jess outline a clear, compassionate roadmap for anyone who has ever felt dismissed, overwhelmed or stuck in a body that will not calm down.Dr. Taz and Dr. Jess discuss: • What functional freeze is and why it shows up in daily life • How nervous system dysregulation drives fatigue, anxiety and chronic symptoms • The role of mold, parasites, toxins and environmental chemicals in chronic illness • Why detox fails when the body does not feel safe • Vagus nerve physiology and dorsal vs ventral vagal states • How trauma, stress and grief reshape hormones, immune function and methylation • Medical dismissal and the reality of normal labs with real symptoms • The drainage pathways that must open before detox • Histamine issues, MCAS, POTS and their connection to the nervous system • Tools that help regulate the system and support healing • How to track progress through sleep, HRV, emotional stability and digestion • Why healing is not linear and why support and community matterAbout Dr. Jessica Peatross Dr. Jessica Peatross  is a functional and environmental medicine expert known for her work on nervous system dysregulation, toxin-driven illness and trauma informed detox. She is the founder of WellnessPlus, an educational platform teaching step-by-step protocols for mold, parasites, drainage and nervous system healing. Her approach blends clinical training with nervous system science to uncover root causes often missed in conventional care.Stay Connected:Connect further to Hol+ at https://holplus.co/- Don’t forget to like, subscribe, and hit the notification bell to stay updated on future episodes of hol+.Follow Dr. JessInstagram: https://instagram.com/dr.jess.md/YouTube: https://youtube.com/@DoctorJessMDWebsite: https://drjessmd.com/  Follow Dr. Taz on Instagram: https://www.instagram.com/drtazmd/https://www.instagram.com/liveholplus/Subscribe to the audio podcast: https://holplus.transistor.fm/subscribeSubscribe to the video podcast: https://www.youtube.com/@DrTazMD/podcastsGet your copy of The Hormone Shift: Balance Your Body and Thrive Through Midlife and MenopauseHost & Production TeamHost: Dr. Taz; Produced by ClipGrowth.com (Producer: Pat Gostek)

Millions of women say the same thing in their late 30s and 40s “I don’t feel like myself anymore.” Fatigue grows, stress tolerance collapses, brain fog hits, and everyday tasks suddenly require more effort. Yet most are told it’s “normal aging,” “just stress,” or “anxiety.”In this hol+ episode, Dr. Taz sits down with functional medicine expert and bestselling author Dr. Mariza Snyder to ask the hard questions about perimenopause, what it is, when does perimenopause start, and why rage, irritability, and cognitive changes are often the earliest symptoms women experience.Together, they unpack why perimenopause is widely misdiagnosed, why progesterone decline shows up long before hot flashes or missed periods, how estrogen fluctuations affect brain function, and why so many women feel like their identity, mood, and capacity are suddenly slipping away.From mood swings, brain fog, and sleep crashes to metabolic slowdowns and rising visceral fat, this conversation reframes perimenopause symptoms as hormone-driven neurological and physiological shifts — not personal weakness, aging, or lack of willpower.You will learn what perimenopause is, what age perimenopause starts, why rage and irritability show up first, and how to track early hormone changes through menstrual patterns, symptoms, biometrics, and stress physiology. Dr. Taz and Dr. Mariza also share lifestyle tools, boundaries, morning and evening routines, and targeted support that help stabilize brain energy, mood, and metabolic health during this transition.Dr. Taz and Dr. Mariza discuss: • What is perimenopause and why it hits earlier than women expect • When does perimenopause start and what age perimenopause typically begins • Why perimenopause rage is real and often the first warning sign • Perimenopause brain fog, cognitive shifts, and declining stress tolerance • Progesterone decline, estrogen fluctuations, and why hormones become unpredictable • Perimenopause vs aging: why symptoms are dismissed or misdiagnosed • Mood swings, irritability, fatigue, and the identity shift many women feel • Early metabolic changes in perimenopause and why belly fat increases • How to track symptoms, cycles, HRV, sleep, and biomarkers for early clues • Tools women can use: routines, nervous system regulation, boundaries, lifestyle resets • When progesterone or estrogen support can make a meaningful difference • Why community and sisterhood become critical for emotional resilienceAbout Dr. Mariza Snyder Dr. Mariza Snyder is a functional practitioner, women's health expert, hormone educator, and bestselling author of The Perimenopause Revolution. With over 15 years of clinical experience, she helps women navigate perimenopause and midlife with clarity, confidence, and science-based tools that support hormone balance, brain health, emotional resilience, and metabolic vitality. Her work empowers women to understand what perimenopause is, recognize early symptoms, and take back control of their health with practical strategies and integrative support.Stay Connected:Connect further to Hol+ at https://holplus.co/- Don’t forget to like, subscribe, and hit the notification bell to stay updated on future episodes of hol+.Follow Dr. Mariza Snyder:Instagram: https://www.instagram.com/drmariza/Podcast: Energized with Dr. Mariza Book: The Perimenopause Revolution Follow Dr. Taz on Instagram: https://www.instagram.com/drtazmd/https://www.instagram.com/liveholplus/Subscribe to the audio podcast: https://holplus.transistor.fm/subscribeSubscribe to the video podcast: https://www.youtube.com/@DrTazMD/podcastsGet your copy of The Hormone Shift: Balance Your Body and Thrive Through Midlife and MenopauseHost & Production TeamHost: Dr. Taz; Produced by ClipGrowth.com (Producer: Pat Gostek)

Subscribe to the video podcast: https://www.youtube.com/@LiveHolPlus/ Your gut is not just a digestion system, it is one of the most powerful control centers in your body. In this episode, Dr. Taz explains how the gut lining, bile, digestive enzymes, and microbiome all work together to shape your hormones, mood, weight, and inflammation. You will learn why gut health is still not standard of care in conventional medicine, how stress, toxins, sleep, and even popular GLP 1 drugs change the microbiome, and what that means for conditions like anxiety, depression, perimenopause, menopause, and stubborn belly fat.Dr. Taz shares: • Why ancient systems called the gut "ground zero" and modern research is finally catching up • The four pillars of gut health: gut lining, digestive enzymes and stomach acid, bile flow, and a diverse microbiome • How leaky gut, SIBO, candida, and low diversity bacteria drive inflammation, brain fog, rashes, and chronic symptoms • The gut brain axis and why up to 90 percent of serotonin and other neurotransmitters are made in the gut • How butyrate and beta glucuronidase affect estrogen recycling, perimenopause, and andropause, leading to estrogen dominance and hormone shifts • The links between microbiome balance, circadian rhythm, GLP 1 medications, and metabolic syndrome and weight gain • A practical step by step protocol using diet changes, collagen, glutamine, enzymes, probiotics, fermented foods, sleep, and stress tools to rebuild gut healthWhether you are dealing with mood changes, hormone chaos, weight that will not budge, or unexplained symptoms that never fully resolve, this episode gives you a clear roadmap to understand your gut and start rebuilding your microbiome from the inside out.Stay Connected:Connect further to Hol+ at https://holplus.co/- Don’t forget to like, subscribe, and hit the notification bell to stay updated on future episodes of hol+.Follow Dr. Taz on Instagram: https://www.instagram.com/drtazmd/https://www.instagram.com/liveholplus/Subscribe to the audio podcast: https://holplus.transistor.fm/subscribeSubscribe to the video podcast: https://www.youtube.com/@DrTazMD/podcastsGet your copy of The Hormone Shift: Balance Your Body and Thrive Through Midlife and MenopauseHost & Production TeamHost: Dr. Taz; Produced by ClipGrowth.com (Producer: Pat Gostek)

Subscribe to the video podcast: https://www.youtube.com/@LiveHolPlus/Cardiovascular disease is still the number one killer, yet guidelines keep pushing cholesterol lower and more people are put on statins for life. In this hol+ episode, Dr. Taz sits down with worlds leading nitric oxide researcher Dr. Nathan S. Bryan to ask hard questions about statin risk versus benefit, why cholesterol alone does not explain heart disease, and what is nitric oxide actually doing inside the body long before a heart attack or stroke. Together, they explore why low or no nitric oxide may be the missing piece behind rising blood pressure, plaque, and dementia, even in people who “follow the rules.”From the benefits of nitric oxide for blood flow, blood pressure, diabetes, and brain health to the surprising impact of antiseptic mouthwash and antacid medications, this conversation reframes cardiovascular and metabolic disease as problems of cell signaling, not just lab numbers. You will learn what nitric oxide is, what does nitric oxide do for the body, why nitric oxide importance is often ignored in standard care, and how to raise nitric oxide through lifestyle, targeted support, and emerging restorative therapies based on decades of nitric oxide research.Dr. Taz and Dr. Bryan discuss:New cholesterol guidelines, statins, and rethinking risk vs benefitWhat is nitric oxide and what does nitric oxide do for the bodyWhy low or no nitric oxide shows up decades before heart attacks and strokeThe benefits of nitric oxide for blood flow, blood pressure, and sexual functionNitric oxide diabetes link and why insulin resistance is often a nitric oxide problemMouthwash and nitric oxide, antacids, fluoride, and the oral microbiomeHow lifestyle, diet, movement, and nasal breathing raise nitric oxide naturallyWhy standard biomarkers are late and vascular function should be tested soonerNitric oxide importance in Alzheimer’s, dementia, and brain blood flowHow to raise nitric oxide safely and what to know about supplements vs “dead beets”About Dr. Nathan S. Bryan Dr. Nathan S. Bryan is a pioneering nitric oxide researcher, molecular medicine scientist, and biotech entrepreneur whose discoveries helped create a billion dollar nitric oxide market. His work has reshaped how we understand cardiovascular disease, metabolic health, nitric oxide diabetes links, and how lifestyle, mouthwash and nitric oxide, and common drugs impact long term health. He is the author of The Secret of Nitric Oxide, where he breaks down what nitric oxide is, what nitric oxide does for the body, and how to raise nitric oxide safely at home using science based tools and lifestyle shifts. Stay Connected:Connect further to Hol+ at https://holplus.co/- Don’t forget to like, subscribe, and hit the notification bell to stay updated on future episodes of hol+.Follow Dr. Nathan S. Bryan:  YouTube: https://www.youtube.com/@DrNathanSBryanNitricOxideInstagram: https://www.instagram.com/drnathansbryan/ Website: https://www.bryantherapeutics.com/ Product: https://n1o1.com/Get The Secret of Nitric Oxide Book here.Follow Dr. Taz on Instagram: https://www.instagram.com/drtazmd/https://www.instagram.com/liveholplus/Subscribe to the audio podcast: https://holplus.transistor.fm/subscribeSubscribe to the video podcast: https://www.youtube.com/@DrTazMD/podcastsGet your copy of The Hormone Shift: Balance Your Body and Thrive Through Midlife and MenopauseHost & Production TeamHost: Dr. Taz; Produced by ClipGrowth.com (Producer: Pat Gostek)00:00 New cholesterol rules, statins, and nitric oxide importance01:00 Mouthwash and nitric oxide, blood pressure, and the oral microbiome01:46 What is nitric oxide and what does nitric oxide do for the body03:06 Why nitric oxide matters for longevity, inflammation, and aging cells04:32 Nobel Prize history and early nitric oxide research06:06 Fingerprint of nitric oxide biology and early disease markers08:13 No nitric oxide before you see plaque, blood pressure, or ED09:26 The American lifestyle and nitric oxide diabetes link10:45 Mouthwash and nitric oxide, fluoride, PPIs, and hidden blockers12:26 Statins, cholesterol guidelines, and questioning “everyone needs a statin”16:11 Cholesterol numbers, Framingham data, and what actually predicts risk19:27 Better heart screening, vascular function, and nitric oxide benefits22:28 First symptoms of low nitric oxide: ED, libido, and rising blood pressure25:04 Mouthwash and nitric oxide causation study, exercise benefits lost27:23 Antacids, reflux meds, and how they shut down nitric oxide27:58 How to raise nitric oxide naturally with food, movement, and sunlight30:19 Nasal breathing, mouth breathing, and nitric oxide delivery to the lungs31:02 Nitric oxide as a hormone and whole body signaling molecule33:18 How to measure, how to replace, and what nitric oxide testing really shows36:45 Inflammation, triglycerides, and tracking nitric oxide benefits in labs38:38 Restorative physiology vs applied pharmacology42:01 Can nitric oxide help heart failure, liver disease, and ascites44:13 Nitric oxide diabetes connection and insulin resistance46:52 Nitric oxide and Alzheimer’s, brain blood flow, and “type 3 diabetes”47:57 Kids, ADHD, diet, and low nitric oxide as a blood flow problem49:08 5G, toxins, and electron flow in biochemistry51:00 Glutathione, nitric oxide transport, and why most supplements miss the mark52:18 Why arginine, citrulline, and most beet products do not fix nitric oxide55:40 Nitruticals, rebuilding nitric oxide and the oral microbiome57:32 Nitric oxide for wounds, skin, and regenerative healing59:19 Reversing disease vs managing decline, and what nitric oxide might change1:00:07 Optimizing human performance with nitric oxide as a foundation1:01:18 Where to learn more from Dr. Nathan Bryan1:01:55 Closing thoughts from Dr. Taz and hol+

Subscribe to the video podcast: https://www.youtube.com/@DrTazMD/podcastsWhat Is PCOS in Women, How It’s Diagnosed? PCOS is not just a gynecology label, it is a whole-body syndrome that is widely missed in the exam room. In this episode, Dr. Taz explains why nearly seventy percent of women go undiagnosed, how PCOS often begins in the prenatal environment, and why it behaves like a metabolic and autoimmune condition. You will learn the signs most people overlook, the labs that actually matter, and a step-by-step plan that starts with the gut, supports the liver, balances blood sugar, and calms cortisol so real healing can begin.Dr. Taz shares: • Why the old Rotterdam criteria miss metabolic, inflammatory, and immune drivers • How prenatal hormones, medications, and toxins can program PCOS risk • The role of hyperandrogenism in insulin resistance, inflammation, acne, and hair loss • Why PCOS looks different by life stage and race, and what that means for care • The exact labs to request: DHT, AMH, free and total testosterone, DHEAS, 17-OHP, fasting insulin, lipids, CRP and more • A holistic protocol that begins with gut repair and liver support, then adds androgen and metabolic tools • How daily stress and the cortisol hum keep PCOS active, and practical ways to turn it downWhether you feel off but cannot explain why, are chasing a diagnosis, or want a long term plan for energy, fertility, and hormone balance, this episode gives you a clear roadmap to understand PCOS and take action.Connect further to Hol+ at https://holplus.co/- Don’t forget to like, subscribe, and hit the notification bell to stay updated on future episodes of hol+.Get your copy of The Hormone Shift: Balance Your Body and Thrive Through Midlife and MenopauseStay ConnectedSubscribe to the audio podcast: https://holplus.transistor.fm/subscribeSubscribe to the video podcast: https://www.youtube.com/@DrTazMD/podcastsFollow Dr. Taz on Instagram:https://www.instagram.com/drtazmd/https://www.instagram.com/liveholplus/Join the conversation on X: https://x.com/@drtazmdTikTok: https://www.tiktok.com/@drtazmdFacebook: https://www.facebook.com/drtazmd/Don’t forget to like, subscribe, and hit the notification bell to stay updated on future episodes of hol+Chapters 00:00 The PCOS epidemic and misdiagnosis 00:27 Dr. Taz’s PCOS story 03:06 Why old criteria fall short 05:09 PCOS as metabolic and autoimmune 08:20 Why PCOS rates are rising 09:14 Prenatal and medication influences 11:05 Childhood and teen clues 15:44 Symptom checklist you can spot 18:42 Eastern medicine patterns to notice 20:32 What to test for PCOS 23:56 How presentation varies by race 30:03 Building a holistic plan 33:37 Gut and liver first 35:16 Androgen, metabolic, and inflammation tools 37:30 Managing cortisol and stress 39:13 Long term roadmap and next steps

Subscribe to the video podcast: https://www.youtube.com/@LiveHolPlus/podcastsMental health is not a simple checklist, it is a whole body story. In this hol+ episode, Dr. Taz sits down with Dr. James Greenblatt, a pioneer of integrative and nutritional psychiatry, to rethink how we approach depression, anxiety, ADHD, and eating disorders through labs, nutrients, hormones, and personalized care.Together, they unpack why so much suffering persists despite more medications, how root cause testing changes outcomes, and why simple shifts like correcting vitamin D, B12, iron, thyroid, zinc, and omega 3 can transform mood and resilience. They also explore nutrigenomics for precision dosing, the real limits of 10 minute telehealth med checks, and where tools like ketamine, psychedelics, and lithium orotate fit only after foundations are in place.From practical lab targets and cost effective protocols to the crossroads of food, sleep, screens, and ADHD, this conversation invites us to see mental health not as a diagnosis to medicate, but as a system to understand and support.Dr. Taz and Dr. Greenblatt discuss:The gap between symptom focused care and root cause testingKey labs for mood, vitamin D, B12, iron, thyroid, hormonesWhy micronutrients come first for eating disordersMTHFR, methylfolate, glutathione, and antidepressant responseNutrigenomics for personalized vitamin and mineral dosingThe risks of quick med stacking and 10 minute checksWhere ketamine, psychedelics, and lithium orotate may help, and when they do notADHD, ultra processed foods, sugary drinks, sleep, and screen timeAbout Dr. James Greenblatt, MDDr. James Greenblatt, MD is a board certified psychiatrist and a pioneer of integrative and nutritional psychiatry. For more than three decades he has treated patients with ADHD, depression, anxiety, and eating disorders using personalized protocols that combine conventional care with targeted nutrients and lab guided precision. He is the author of multiple books including Finally Focused and the upcoming Finally Hopeful.Connect further to Hol+ at https://holplus.co/- Don’t forget to like, subscribe, and hit the notification bell to stay updated on future episodes of hol+.Get your copy of The Hormone Shift: Balance Your Body and Thrive Through Midlife and MenopauseStay ConnectedSubscribe to the audio podcast: https://holplus.transistor.fm/subscribeSubscribe to the video podcast: https://www.youtube.com/@DrTazMD/podcastsFollow Dr. Taz on Instagram:https://www.instagram.com/drtazmd/https://www.instagram.com/liveholplus/Join the conversation on X: https://x.com/@drtazmdTikTok: https://www.tiktok.com/@drtazmdFacebook: https://www.facebook.com/drtazmd/Follow Dr. James Greenblatt MD: Website: https://jamesgreenblattmd.com Platform: https://PsychiatryRedefined.org Instagram: https://instagram.com/psychiatry_redefinedDon’t forget to like, subscribe, and hit the notification bell to stay updated on future episodes of hol+00:00 Introduction, testing gap and the B12 tragedy01:31 Pharma model and 10 minute med checks02:37 Framing the crisis and why patients feel stuck05:49 How psychiatry arrived at symptom based meds07:29 What to test, hormones and core nutrients10:49 The Whole Body Map explained12:39 Vitamin D, B12, iron, thyroid, practical targets17:52 Why meds fail without nutrition18:23 Eating disorders, zinc, omega 3, methylfolate24:33 MTHFR, folate, and glutathione26:34 Nutrigenomics and personalized dosing29:51 Ketamine and psychedelics, proceed with caution32:26 Lithium orotate, irritability and dementia research38:57 Polypharmacy, slowing down, doing the work43:21 ADHD, diet, sleep, screens, lifestyle links46:28 Where to learn more, resources, closing (00:00) - Chapter 1 (00:00) - Introduction, testing gap and the B12 tragedy (01:31) - Pharma model and 10 minute med checks (02:37) - Framing the crisis and why patients feel stuck (05:49) - How psychiatry arrived at symptom based meds (07:29) - What to test, hormones and core nutrients (10:49) - The Whole Body Map explained (12:39) - Vitamin D, B12, iron, thyroid, practical targets (17:52) - Why meds fail without nutrition (18:23) - Eating disorders, zinc, omega 3, methylfolate (24:33) - MTHFR, folate, and glutathione (26:34) - Nutrigenomics and personalized dosing (29:51) - Ketamine and psychedelics, proceed with caution (32:26) - Lithium orotate, irritability and dementia research (38:57) - Polypharmacy, slowing down, doing the work (43:21) - ADHD, diet, sleep, screens, lifestyle links (46:28) - Where to learn more, resources, closing

Subscribe to the video podcast: https://www.youtube.com/@DrTazMD/podcastsSilent inflammation is not a buzzword, it is the quiet engine behind fatigue, brain fog, stubborn weight, anxiety, gut issues, and hormone chaos. In this episode, Dr. Taz explains what silent inflammation really is, how the cortisol hum keeps your body on alert, and why modern life, from blue light to isolation, adds fuel to the fire. You will learn how the hypothalamus, pituitary, and pineal act as a control hub, why normal labs can miss the gray zone, and the practical steps that calm your system so real healing can begin.Dr. Taz shares: • Why silent inflammation can start in the prenatal environment and echo through generations • How chronic cortisol activation keeps you inflamed even when labs look normal • The role of the hypothalamus pituitary axis in hormones, mood, and energy • How blue light, toxins, poor sleep, and isolation raise your inflammatory load • Simple daily practices that lower cortisol and reset your nervous system • Why community, nature, and deep sleep are non negotiable for healing • Tools like meditation, sound therapy, and scalp work that help flip the stress switchWhether you feel off but cannot explain why, are chasing a diagnosis, or want a long term plan for energy, focus, and hormone balance, this episode gives you a clear roadmap to reduce inflammation and reclaim your vitality.Connect further to Hol+ at https://holplus.co/- Don’t forget to like, subscribe, and hit the notification bell to stay updated on future episodes of hol+.Get your copy of The Hormone Shift: Balance Your Body and Thrive Through Midlife and MenopauseStay ConnectedSubscribe to the audio podcast: https://holplus.transistor.fm/subscribe Subscribe to the video podcast: https://www.youtube.com/@DrTazMD/podcastsFollow Dr. Taz on Instagram:https://www.instagram.com/drtazmd/ https://www.instagram.com/liveholplus/Join the conversation on X: https://x.com/@drtazmdTikTok: https://www.tiktok.com/@drtazmdFacebook: https://www.facebook.com/drtazmd/Don’t forget to like, subscribe, and hit the notification bell to stay updated on future episodes of hol+Chapters00:00 What is Silent Inflammation02:00 The Cortisol Hum and Chronic Stress04:00 Intergenerational and Environmental Inflammation07:00 The Brain’s Role: Hypothalamus and Hormones10:00 Hidden Symptoms Most Labs Miss13:00 Daily Habits That Calm Inflammation17:00 Meditation, Sound, and Nervous System Reset20:00 Rewriting Your Inflammatory Story for Future Generations

Menopause isn’t just a biological transition - it’s an awakening. In this Hol+ episode, Dr. Taz sits down with Kelly McGinty and Dr. Patricia Singh, co-founders of Trip Home and co-authors of “My Solo P: Uncovering the Magic of Menopause through Psilocybin,” to explore how psychedelic-assisted therapy and holistic healing are reshaping the way we talk about women’s health, mental well-being, and midlife transformation.Together, they dive into the science and spirituality of psilocybin, how microdosing and medicinal mushrooms can support emotional balance, and why this powerful approach is giving women permission to reclaim joy, presence, and purpose.From the challenges of legal access and stigma to deeply personal stories of healing from burnout, trauma, and self-judgment, this conversation invites us to see menopause not as an ending - but as an initiation into freedom, wisdom, and wholeness.Dr. Taz, Kelly, and Dr. Singh discuss:The intersection of science, spirit, and women’s healthHow psychedelics and psilocybin therapy can ease menopause symptoms and emotional transitionsHealing from trauma, burnout, and identity lossSafe and ethical practices for microdosing and harm reductionThe power of self-awareness, community, and holistic self-careWhether you’re curious about psychedelics, navigating menopause, or seeking new paths to mental health and balance, this episode is a roadmap to rediscovery and transformation.Get the book: Mycelopuase: Uncovering the Magic of Menopause through Psilocybin: https://store.bookbaby.com/book/mycelopause Connect with Trip HōM, SPC. You can find them at www.triphom.comChapters00:00 Introduction & Welcome00:31 Meet the Guests: Dr. Patricia Singh & Kelly McGinty01:52 Why Psilocybin and Menopause?03:07 History of Medicinal Mushrooms & Psychedelics07:13 Burnout, Trauma, and the Path to Psychedelic Therapy10:49 How Psychedelic-Assisted Therapy Works14:41 The Science Behind Psilocybin16:41 Access, Safety, and Legalization19:07 Who Should (and Shouldn’t) Consider Psychedelic Therapy?21:18 Women, Hormones, and the Menopausal Journey25:59 Self-Care, Self-Awareness, and Transformation29:47 Trauma, Menopause, and Healing the Body36:47 Client Stories & Real-Life Transformations39:01 The Book: Myceliopa & Trip Home’s Mission42:01 Changing the Conversation Around Menopause44:37 Where to Learn More & Final Thoughts46:06 What Makes You Hol?Stay ConnectedSubscribe to the audio podcast: https://holplus.transistor.fm/subscribeSubscribe to the video podcast: https://www.youtube.com/@DrTazMD/podcastsFollow Dr. Taz on Instagram: https://www.instagram.com/drtazmd/https://www.instagram.com/liveholplus/Join the conversation on X: https://x.com/@drtazmdTikTok: https://www.tiktok.com/@drtazmdFacebook: https://www.facebook.com/drtazmd/Host & Production TeamHost: Dr. Taz; Produced by Rainbow Creative (Executive Producer: Matthew Jones; Lead Producer: Lauren Feighan; Editors: Jeremiah Schultz and Patrick Edwards)Don’t forget to like, subscribe, and hit the notification bell to stay updated on future episodes of hol+

Subscribe to the video podcast: https://www.youtube.com/@DrTazMD/podcastsFreedom isn’t just about walking outside prison walls, it’s about breaking free from the invisible prisons of shame, anger, and limiting beliefs. In this Hol+ episode, Dr. Taz sits down with Shaka Senghor, bestselling author and inspirational speaker, to uncover how solitary confinement, journaling, and vulnerability became the keys to his transformation.Together they explore how trauma shows up in daily life, why shame keeps us disconnected, and how to rewrite the narratives that hold us back. From books that sparked healing to the hidden prisons we all carry, this is a masterclass in resilience, authenticity, and the power of owning your story.Dr. Taz and Shaka discuss:Growing up in Detroit and the path to incarcerationHow books and journaling transformed solitary confinementAnger, shame, and the healing power of reflectionInvisible prisons of doubt, shame, and limiting beliefsThe shock of reentry into a changed worldWhy vulnerability attracts vulnerabilityBreaking cycles for family and communityChoosing joy, love, and higher narrativesHow to build authentic connections as men and womenPractical tools for rewriting your life storyTopics Covered:Trauma, anger, and their hidden impactJournaling, mindfulness, and self-study as survivalThe importance of vulnerability in healingInternal narratives vs external ceilingsInvisible prisons in everyday lifeJoy, love, and higher purpose after hardshipRedefining strength and resilienceConnect further to Hol+ at https://holplus.co/- Don’t forget to like, subscribe, and hit the notification bell to stay updated on future episodes of hol+.About Shaka Senghor:Shaka Senghor is an inspirational speaker, entrepreneur, and author of the New York Times bestselling books Writing My Wrongs and Letters to the Sons of Society. A sought-after resilience expert and recognized "Soul Igniter" in Oprah's inaugural SuperSoul 100, Senghor has captivated and transformed global audiences with his extraordinary journey from incarceration to influence. Through raw authenticity and profound insight, he doesn't just share his story—he equips others with the exact resilience practices that fueled his own remarkable transformation, proving that reinvention isn't just possible—it's within everyone's reach.Stay ConnectedSubscribe to the audio podcast: https://holplus.transistor.fm/subscribeSubscribe to the video podcast: https://www.youtube.com/@DrTazMD/podcastsFollow Dr. Taz on Instagram: https://www.instagram.com/drtazmd/https://www.instagram.com/liveholplus/Join the conversation on X: https://x.com/@drtazmdTikTok: https://www.tiktok.com/@drtazmdFacebook: https://www.facebook.com/drtazmd/Connect with Shaka Senghorhttps://www.shakasenghor.com/https://www.instagram.com/shakasenghorHost & Production TeamHost: Dr. Taz; Produced by Rainbow Creative (Executive Producer: Matthew Jones; Lead Producer: Lauren Feighan; Editors: Jeremiah Schultz and Patrick Edwards)Don’t forget to like, subscribe, and hit the notification bell to stay updated on future episodes of hol+Chapters00:00 Introduction03:44 Shaka's Early Life and Descent into Crime06:15 The Turning Point: Solitary Confinement and Self-Reflection07:09 The Power of Mentorship and Literacy in Prison09:33 Journaling: A Path to Healing and Self-Discovery19:51 Reintegration: Challenges and Triumphs27:28 The Power of Vulnerability29:37 Understanding Anger and Shame31:13 Navigating Masculinity and Vulnerability34:11 Overcoming Hidden Prisons40:45 Breaking Free from Life's Prisons51:15 Final Thoughts and Reflections

Subscribe to the video podcast: https://www.youtube.com/@DrTazMD/podcastsWhat happens when the “healthy one” gets cancer? Samantha Harris shares the diagnosis that changed everything.In this deeply moving episode of Hol+, Dr. Taz MD sits down with Emmy-nominated TV host, author, and breast cancer survivor Samantha Harris to unpack her harrowing and empowering health journey—from being blindsided by a breast cancer diagnosis at 40, to navigating a recurrence a decade later, despite living what she thought was the healthiest lifestyle.Best known as the radiant host of Dancing with the Stars and Entertainment Tonight, Samantha takes us behind the scenes of her transformation from fitness icon to fierce advocate, author, and functional health warrior. She opens up about her fight to be taken seriously by doctors, why mammograms failed to detect her cancer, and the powerful philosophy she developed in the aftermath: “10% Toxic.”This conversation is packed with raw honesty, actionable insights, and the kind of wisdom that only comes from walking through fire—twice.Samantha opens up about:How a “normal” mammogram nearly cost her everythingThe misdiagnosis that delayed her treatment for monthsHer decision to skip chemo and radiation—and why she still doesn’t regret itThe power of intuition in healing and early detectionHow to build your “doctor squad” and advocate for yourselfHer 10% toxic philosophy to reduce overwhelm and reclaim wellnessHow she now supports women around the world through her book, podcast, and retreatsWhether you’ve faced cancer, know someone who has, or simply want to prevent disease in a world full of overwhelm, this episode offers real talk, real tools, and real hope.Connect further to hol+ at https://holplus.co/- Don’t forget to like, subscribe, and hit the notification bell to stay updated on future episodes of hol+.About Samantha HarrisA 4-time Emmy Award nominee, she’s best known for lighting up our screens for 8 unforgettable seasons as the host of Dancing with the Stars—and she also won the Emmy for her years on Entertainment Tonight! She’s the only host to have ever anchored every major national entertainment news program from Access Hollywood and EXTRA to E! News and more.But behind the bright lights, life took an unexpected turn. At just 40 years old, this devoted wife and mom of two young daughters faced a shocking breast cancer diagnosis. A decade later, at 50, she was blindsided yet again by a recurrence. But Samantha Harris didn’t just survive—she redefined what it means to thrive. She turned her journey into a mission—becoming a Certified Health Coach, and the bestselling author and dynamic host of the top-rated podcast, Your Healthiest Healthy. You’ve seen her as a trusted health expert on Good Morning America, FOX & Friends, The Doctors, HLN’s Morning Express, and more—sharing practical, life-changing wellness strategies. As a National Ambassador for the world’s largest breast cancer foundation, Susan G. Komen, she’s on a mission to uplift, empower, and equip others to take control of their health like never before—one manageable step at a time.Stay ConnectedSubscribe to the audio podcast: https://holplus.transistor.fm/subscribeSubscribe to the video podcast: https://www.youtube.com/@DrTazMD/podcastsFollow Dr. Taz on Instagram: https://www.instagram.com/drtazmd/https://www.instagram.com/liveholplus/Join the conversation on X: https://x.com/@drtazmdTikTok: https://www.tiktok.com/@drtazmdFacebook: https://www.facebook.com/drtazmd/Connect with Samantha Harris​https://samantha-harris.com/https://www.instagram.com/samanthaharristv/Host & Production TeamHost: Dr. Taz; Produced by Rainbow Creative (Executive Producer: Matthew Jones; Lead Producer: Lauren Feighan; Editors: Jeremiah Schultz and Patrick Edwards)Don’t forget to like, subscribe, and hit the notification bell to stay updated on future episodes of hol+Chapters00:00 Introduction02:43 Samantha's Health Journey Begins05:28 Navigating the Medical System07:21 Making Treatment Decisions15:38 Treatment Options and Outcomes31:32 Recovery and Genetic Testing32:54 The Journalist's Deep Dive into Breast Cancer34:15 Exercise and Lifestyle Changes36:03 Diet and Nutrition Misconceptions37:54 Balancing Career and Health40:27 The Recurrence and New Insights47:03 The 10% Toxic Philosophy50:06 Practical Tips for a Healthier Life01:02:48 Final Thoughts and Conclusion