Alzheimer’s Breakthrough with Dr. Josh Helman, MD

👉 Get Dr. Josh's Top 10 Supplements for Alzheimer's at http://drjosh.com/gift.👉 Get Dr. Josh's GreenBrainsMD™ Supplements - custom-crafted to support brain health at every stage — from daily prevention to deeper cellular support.🧠 BrainEase™ — Magnesium - Daily Brain Support for Cognitive Clarity & Healthy Aging🛡️ BrainGuard™ — Curcumin - Advanced Neuro Support & Cellular Protection✨ BrainRevive™ — Liposomal Glutathione for Brain & Antioxidant SupportWant to learn more? Head to http://drjosh.com/buyFor personalized guidance and support with reversing & preventing Alzheimer's, you can reach out to Dr. Josh Helman directly. Visit his website at http://drjosh.com or contact his office at (407) 221-8841 to learn more about how he can help your journey to a healthier brain.=====================================================Can old brain cells be made biologically younger again? In Episode #87 of Alzheimer's Breakthrough, host Dr. Josh Helman, MD is joined by Dr. Sam Perli, PhD, a former MIT presidential fellow, early CRISPR pioneer, and postdoctoral fellow with Nobel laureate Shinya Yamanaka.In this deep dive, Dr. Perli shares his personal journey from AI and computer science into biological engineering, the revolutionary power of CRISPR, and how cellular reprogramming factors can turn back the biological clock on aging neurons. Together, they explore why treating Alzheimer's requires moving beyond single-target amyloid plaque therapies toward a holistic, multi-pronged approach that includes neurogenesis, anti-inflammation, therapeutic peptides, and gut-brain microbiome health.=====================================================Connect with Dr. Sam Perli, PhD:-LinkedIn- linkedin.com/in/samperli-Personal website- samperli.com-Thinkhat AI (Chief Scientific Officer)- thinkhat.ai/team=====================================================Connect with Dr. Josh Helman, MD:- Substack - https://drjoshmd.substack.com/- Instagram - https://www.instagram.com/greenbrainsMD - Facebook - https://www.facebook.com/greenbrainsmd/- LinkedIn - https://www.linkedin.com/in/doctorjosh- TikTok - https://www.tiktok.com/@greenbrainsmd - Website - https://DrJosh.com=====================================================Chillout by AudioCoffee | https://www.audiocoffee.net/Music promoted by https://www.chosic.com/free-music/all/Creative Commons CC BY-SA 3.0https://creativecommons.org/licenses/by-sa/3.0/=====================================================Disclaimer: Please remember that this podcast is for informational purposes only and is not intended as medical advice. Always consult your doctor or healthcare professional before making any changes to your treatment plan.#Alzheimers #BrainHealth #CRISPR #YamanakaFactors #Neurogenesis #Longevity #ReversingAging #ArtificialIntelligence #DrJoshHelman #DrSamPerli #AlzheimersBreakthrough

👉 Get Dr. Josh's Top 10 Supplements for Alzheimer's at http://drjosh.com/gift.👉 Get Dr. Josh's GreenBrainsMD™ Supplements - custom-crafted to support brain health at every stage — from daily prevention to deeper cellular support.🧠 BrainEase™ — Magnesium - Daily Brain Support for Cognitive Clarity & Healthy Aging🛡️ BrainGuard™ — Curcumin - Advanced Neuro Support & Cellular Protection✨ BrainRevive™ — Liposomal Glutathione for Brain & Antioxidant SupportWant to learn more? Head to http://drjosh.com/buyFor personalized guidance and support with reversing & preventing Alzheimer's, you can reach out to Dr. Josh Helman directly. Visit his website at http://drjosh.com or contact his office at (407) 221-8841 to learn more about how he can help your journey to a healthier brain.=====================================================What happens to the brain when it gets hit with multiple environmental and biological toxins at the same time? In Episode #86 of Alzheimer's Breakthrough, host Dr. Josh Helman, MD welcomes back Dr. Mobeen Syed, MD (Dr. Been) to discuss how mold toxins, bacterial endotoxins (LPS), and viral spike proteins interact to accelerate memory loss and cognitive decline.Dr. Mobeen and Dr. Josh examine the multi-hit model of neurodegeneration, detailing how initial exposures to mycotoxins (such as Ochratoxin A) or bacterial LPS prime the brain's innate immune cells—microglia. This priming alters cellular metabolism and programs microglia for hyper-reactive inflammation. When a subsequent trigger like the SARS-CoV-2 spike protein occurs, it can spark severe dysregulated inflammation, synaptic pruning, myelin sheath breakdown, and hippocampal dysfunction leading to brain fog and cognitive decline.In this Episode:00:00 – How Mold, Bacterial Toxins & Spike Protein May Affect the Brain03:00 – The Four Key Concepts: Priming, Multi-Hit & Brain Inflammation08:00 – How Mold Toxins and Spike Protein Activate Microglia14:00 – How Activated Microglia Damage Synapses, Myelin & Memory20:00 – The Blood-Brain Barrier: 5 Ways Inflammation Reaches the Brain27:00 – NLRP3 Inflammasomes: From Cellular Damage to Brain Fog34:00 – How Multiple Inflammatory Hits May Affect Memory & Alzheimer's40:00 – Key Takeaways: Mold Exposure, Immune Dysregulation & Brain Health44:00 – Dr. Josh & Dr. Mobeen Discuss Mold, Gut Health and Kidney Damage48:00 – Final Lessons, Where to Find Dr. Mobeen & Closing Remarks=====================================================Connect with Dr. Mobeen Syed, MD:-Website- https://www.drbeen.com-YouTube (Dr. Been Medical Lectures)- https://www.youtube.com/user/USMLEOnline-Facebook- https://www.facebook.com/drbeenmedical/-X (Twitter)- https://twitter.com/drbeen_medical=====================================================Connect with Dr. Josh Helman, MD:- Substack - https://drjoshmd.substack.com/- Instagram - https://www.instagram.com/greenbrainsMD- Facebook - https://www.facebook.com/greenbrainsmd/- LinkedIn - https://www.linkedin.com/in/doctorjosh- TikTok - https://www.tiktok.com/@greenbrainsmd- Website - https://DrJosh.com=====================================================Chillout by AudioCoffee | https://www.audiocoffee.net/Music promoted by https://www.chosic.com/free-music/all/Creative Commons CC BY-SA 3.0https://creativecommons.org/licenses/by-sa/3.0/=====================================================Disclaimer: Please remember that this podcast is for informational purposes only and is not intended as medical advice. Always consult your doctor or healthcare professional before making any changes to your treatment plan.#Alzheimers #BrainHealth #Microglia #ImmuneSystem #MoldToxicity #SpikeProtein #AlzheimersBreakthrough #DrJoshHelman #DrBeen #BrainFog #Neuroinflammation #DementiaResearch #BloodBrainBarrier #Mycotoxins #MultiHitModel #Ochratoxin #CognitiveDecline #FunctionalMedicine #Neurology

👉 Get Dr. Josh's Top 10 Supplements for Alzheimer's at http://drjosh.com/gift.👉 Get Dr. Josh's GreenBrainsMD™ Supplements - custom-crafted to support brain health at every stage — from daily prevention to deeper cellular support.🧠 BrainEase™ — Magnesium - Daily Brain Support for Cognitive Clarity & Healthy Aging🛡️ BrainGuard™ — Curcumin - Advanced Neuro Support & Cellular Protection✨ BrainRevive™ — Liposomal Glutathione for Brain & Antioxidant SupportWant to learn more? Head to http://drjosh.com/buyFor personalized guidance and support with reversing & preventing Alzheimer's, you can reach out to Dr. Josh Helman directly. Visit his website at http://drjosh.com or contact his office at (407) 221-8841 to learn more about how he can help your journey to a healthier brain.=====================================================Could our understanding of the brain’s immune system be completely rewritten? In this episode of Alzheimer's Breakthrough, host Dr. Josh Helman, MD speaks with Dr. Julia Belk, PhD from Stanford University about her ground-breaking research published in Nature.Dr. Belk and her team discovered that in adult humans, microglia the resident immune cells responsible for maintaining brain health are not permanently isolated in the brain throughout life as previously believed. Instead, they are actively replaced by circulating immune cells originating from the blood and bone marrow. This paradigm-shifting discovery opens extraordinary new possibilities for treating Alzheimer’s disease, leveraging engineered cell therapies, and crossing the blood-brain barrier!In this episode:00:00 Introduction: Can Blood Help the Aging Brain?03:00 What Are Microglia and Why Do They Matter?07:00 The Surprising Link Between Blood Mutations and Alzheimer’s12:00 How Blood Cells Replace the Brain’s Immune Cells19:00 Why Human Brain Aging Differs from Animal Models27:00 Can Microglia Lead to New Alzheimer’s Treatments?36:00 Future Therapies, Gene Editing, and the Brain’s Immune System=====================================================Connect with Dr. Julia Belk, PhD:-X (Twitter)- https://x.com/juliabelk-Email- [email protected]=====================================================Connect with Dr. Josh Helman, MD:- Substack - https://drjoshmd.substack.com/- Instagram - https://www.instagram.com/greenbrainsMD- Facebook - https://www.facebook.com/greenbrainsmd/- LinkedIn - https://www.linkedin.com/in/doctorjosh- TikTok - https://www.tiktok.com/@greenbrainsmd- Website - https://DrJosh.com=====================================================Chillout by AudioCoffee | https://www.audiocoffee.net/Music promoted by https://www.chosic.com/free-music/all/Creative Commons CC BY-SA 3.0https://creativecommons.org/licenses/by-sa/3.0/=====================================================Disclaimer: Please remember that this podcast is for informational purposes only and is not intended as medical advice. Always consult your doctor or healthcare professional before making any changes to your treatment plan.#Alzheimers #Neuroscience #Stanford #BrainHealth #Microglia #ImmuneSystem #MedicalResearch #NatureJournal #AlzheimersBreakthrough #DrJoshHelman #JuliaBelk #DementiaResearch #BrainAging #CRISPR #GeneEditing #Immunology #BloodBrainBarrier #AmyloidPlaques #TauTangles #CellTherapy

👉 Get Dr. Josh's Top 10 Supplements for Alzheimer's at http://drjosh.com/gift.👉 Get Dr. Josh's GreenBrainsMD™ Supplements - custom-crafted to support brain health at every stage — from daily prevention to deeper cellular support.🧠 BrainEase™ — Magnesium - Daily Brain Support for Cognitive Clarity & Healthy Aging🛡️ BrainGuard™ — Curcumin - Advanced Neuro Support & Cellular Protection✨ BrainRevive™ — Liposomal Glutathione for Brain & Antioxidant SupportWant to learn more? Head to http://drjosh.com/buyFor personalized guidance and support with reversing & preventing Alzheimer's, you can reach out to Dr. Josh Helman directly. Visit his website at http://drjosh.com or contact his office at (407) 221-8841 to learn more about how he can help your journey to a healthier brain.=====================================================In this video, Gina interviews double board-certified doctor Dr. Josh about his new Green Brains MD supplement line and why glutathione is the foundational "master detoxifier" for your body and brain.Discover why traditional glutathione capsules often fail to absorb in the gut, how the liquid Brain Revive formula works by absorbing directly in the mouth, and how removing toxins like heavy metals, pesticides, plastics, and mold can help lift brain fog and support conditions like Alzheimer's and dementia. Dr. Josh also breaks down his Get Your Brain Back bundle featuring Brain Ease (magnesium) and Brain Guard (curcumin) and shares a critical warning about counterfeit supplements sold on Amazon.In this Episode:00:00 – Why Dr. Josh Is Excited About Glutathione02:30 – How to Take Liquid Glutathione05:30 – Glutathione, Magnesium & Curcumin09:30 – Why “Glutathione First” Matters14:30 – Choosing Quality Supplements & Getting Started=====================================================Connect with Gina Carr, MBA:-Website: https://ginacarr.com-LinkedIn: https://www.linkedin.com/in/ginacarr/=====================================================Connect with Dr. Josh Helman, MD:- Substack - https://drjoshmd.substack.com/- Instagram - https://www.instagram.com/greenbrainsMD- Facebook - https://www.facebook.com/greenbrainsmd/- LinkedIn - https://www.linkedin.com/in/doctorjosh- TikTok - https://www.tiktok.com/@greenbrainsmd- Website - https://DrJosh.com=====================================================Chillout by AudioCoffee | https://www.audiocoffee.net/Music promoted by https://www.chosic.com/free-music/all/Creative Commons CC BY-SA 3.0https://creativecommons.org/licenses/by-sa/3.0/=====================================================Disclaimer: Please remember that this podcast is for informational purposes only and is not intended as medical advice. Always consult your doctor or healthcare professional before making any changes to your treatment plan.#Glutathione #BrainHealth #BrainFog #DrJosh #GreenBrainsMD #BrainRevive #MasterDetoxifier #Detoxification #GetYourBrainBack #BrainEase #BrainGuard #Supplements #LiquidGlutathione #HeavyMetalDetox

👉 Get Dr. Josh's Top 10 Supplements for Alzheimer's at http://drjosh.com/gift.👉 Get Dr. Josh's GreenBrainsMD™ Supplements - custom-crafted to support brain health at every stage — from daily prevention to deeper cellular support.🧠 BrainEase™ — Magnesium - Daily Brain Support for Cognitive Clarity & Healthy Aging🛡️ BrainGuard™ — Curcumin - Advanced Neuro Support & Cellular Protection✨ BrainRevive™ — Liposomal Glutathione for Brain & Antioxidant SupportWant to learn more? Head to http://drjosh.com/buyFor personalized guidance and support with reversing & preventing Alzheimer's, you can reach out to Dr. Josh Helman directly. Visit his website at http://drjosh.com or contact his office at (407) 221-8841 to learn more about how he can help your journey to a healthier brain.=====================================================Why do current Alzheimer's treatments fall short, and what actually keeps your brain sharp as you age? Dr. Bob Bilder breaks down how memory and attention work across distributed brain networks, why forgetting non-essential information is actually a vital brain function, and how wisdom and high-level executive thinking can improve over time. They also discussed the surprising connection between hearing loss and cognitive decline, emotional changes in dementia.In this episode, Dr. Josh speaks with Dr. Bob Bilder, PhD, a professor of neuroscience and psychology at UCLA with decades of research experience. Together, they explore the real science behind aging, memory loss, Alzheimer's disease, and actionable lifestyle habits that protect brain function over time.In this Episode:00:00 – Introduction & What Causes Alzheimer’s?05:30 – Lifestyle Factors That May Protect Brain Health14:00 – PET Scans, Alzheimer’s Diagnosis & Brain Imaging22:00 – Working Memory, Memory Loss & Brain Function30:00 – Multitasking, Attention & Hearing Loss38:00 – Emotions, Happiness & Purpose in Aging45:00 – The Best Habits for a Healthier Brain & Longevity=====================================================Connect with Dr. Bilder, PhD:-X (Twitter): https://x.com/rmbilder (@rmbilder)=====================================================Connect with Dr. Josh Helman, MD:- Substack - https://drjoshmd.substack.com/- Instagram - https://www.instagram.com/greenbrainsMD - Facebook - https://www.facebook.com/greenbrainsmd/- LinkedIn - https://www.linkedin.com/in/doctorjosh- TikTok - https://www.tiktok.com/@greenbrainsmd - Website - https://DrJosh.com=====================================================Chillout by AudioCoffee | https://www.audiocoffee.net/Music promoted by https://www.chosic.com/free-music/all/Creative Commons CC BY-SA 3.0https://creativecommons.org/licenses/by-sa/3.0/=====================================================Disclaimer: Please remember that this podcast is for informational purposes only and is not intended as medical advice. Always consult your doctor or healthcare professional before making any changes to your treatment plan.#BrainHealth #Neuroscience #AlzheimersDisease #Memory #HealthyAging #DrBobBilder #DrJosh #UCLA #Longevity #Neuroplasticity