Hormones, Metabolism & You!

This episode is as raw as it gets as I open up about my personal journey with endometriosis and everything it has taken from me and taught me along the way. I share what it really feels like to live with pain that gets dismissed, the long road to diagnosis, and the emotional and physical toll this condition can have on your body, your relationships, and your future. Through my own story, I break down what endometriosis actually is, why it is so often misunderstood, and the critical signs and symptoms so many women are told to ignore. We also dive into the real, often confusing world of treatment options, from surgery to medications and everything in between, and where both conventional and functional medicine can support you or fall short. I walk you through the questions I wish I would have asked sooner, what I learned the hard way about recurrence and fertility, and what my healing process has looked like after surgery. Whether you are currently struggling, searching for answers, or supporting someone who is, this episode is here to validate your experience and give you clarity, direction, and hope. Topics We Cover in This Episode:  The signs your body may be giving you that are easy to overlook but deeply important Why so many women are told everything is “normal” when it isn’t The hidden reasons diagnosis can take years and what to do about it The truth about treatment options and what most providers don’t fully explain What recurrence actually looks like and how to think about long term healing The connection between endometriosis, fertility, and miscarriage that isn’t talked about enough The questions that can completely change your care and outcomes What I wish I had known before making major medical decisions You deserve answers, support, and a care plan that actually sees you. Tune in, take what speaks to you, and let this be the beginning of advocating for your health in a whole new way. Resources & Links >>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ << 📲 Follow Dr. Cassie Smith & Modern Endocrine 💻 Website:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modern-endocrine.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠  📸 Instagram:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.instagram.com/modernendocrine_/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠  🌟 Facebook:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.facebook.com/ModernEndocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠  📽️ YouTube:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.youtube.com/@modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠  🕹️ TikTok:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.tiktok.com/@modernendocrine?lang=en⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠  📰 Newsletter:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://linktr.ee/modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠  ➡️ Disclaimer:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modernendocrineokc.com/disclaimer-6353⁠

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠<< What if doing everything “right” still leaves you feeling off because your health is not actually optimal? In this episode of Hormones, Metabolism, and You, Dr. Cassie Smith sits down with Joe Miller, founder of 1st Optimal, to talk about what happens when you are doing all the “right” things but still do not feel like yourself. They unpack why normal labs do not always mean optimal health, why women are often dismissed when symptoms do not fit neatly into a standard workup, and how coaching can help turn information into actual progress. Joe also shares how his wife’s complex hormone journey pushed him deeper into functional medicine and why advanced testing, personalized support, and gut-focused care can be the difference between staying stuck and finally moving forward. Episode Highlights Joe’s path from the fitness and health industry into functional medicine and hormone optimization How his wife’s complicated estrogen symptoms and poor hormone metabolism changed everything Why women’s hormone cases are often more complex than men’s and require a broader lens The connection between gut health and symptoms like brain fog, bloating, fatigue, and weight struggles How GI map testing can identify dysbiosis, permeability issues, and digestive dysfunction Why fiber, hydration, protein, sleep, and walking still matter, even when advanced testing is involved The role of health coaches in helping women stop chasing perfection and start making real progress Why progress should be realistic and personalized instead of built around shame or all-or-nothing thinking The importance of removing inflammatory foods while supporting digestion and rebuilding the gut Joe’s reminder that when people feel dismissed by “normal,” they still deserve deeper answers About Joe Miller Joe Miller is the founder of 1st Optimal, a functional medicine and health optimization company focused on hormones, gut health, energy, and body composition. He has helped more than 10,000 women and men improve hormones, metabolism, digestion, and weight loss through advanced lab testing, MD-led HRT, and personalized coaching. His work is rooted in a practical, supportive approach that helps people uncover why they feel off and build a plan that actually works. Connect with Joe Miller 📧 Email: joe.miller@1stoptimal.com 📞 Phone: (586) 491-3369 📸 Instagram: @joemiller1o | @1stoptimal | @1stoptimalpodcast 🎵 TikTok: @joemiller1o 🐦 Twitter/X: @jmiller4252 ▶️ YouTube: 1st Optimal 🌐 Facebook: Joe Miller 📲 Follow Dr. Cassie Smith & Modern Endocrine 💻 Website:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modern-endocrine.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📸 Instagram:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.instagram.com/modernendocrine_/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🌟 Facebook:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.facebook.com/ModernEndocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📽️ YouTube:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.youtube.com/@modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🕹️ TikTok:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.tiktok.com/@modernendocrine?lang=en⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📰 Newsletter:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://linktr.ee/modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ➡️ Disclaimer:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modernendocrineokc.com/disclaimer-6353⁠

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠<< What if one of the most overlooked drivers of inflammation, fatigue, brain fog, and hormone imbalance is something most people rarely think about… their mouth? In this episode of Hormones, Metabolism, and You, Dr. Cassie Smith sits down with Dr. Michelle Jorgensen, DDS, a biologic dentist and founder of Living Well with Dr. Michelle, to explore the powerful connection between oral health and whole-body wellness. After experiencing severe mercury toxicity from years of drilling out silver fillings as a traditional dentist, Dr. Jorgensen was forced to rethink everything she had been taught about dentistry and health. That journey led her to study functional medicine, nutrition, and biologic dentistry to understand how dental issues can influence the entire body. Together, Dr. Cassie and Dr. Michelle unpack some of the biggest questions patients have about dental health, including mercury fillings, root canals, fluoride, bad breath, and the surprising ways dental infections may contribute to systemic disease. If you have ever wondered whether hidden dental issues could be affecting your energy, hormones, or metabolism, this episode may help you connect some important dots. Key Takeaways • Your mouth is part of your overall health system, and dental issues can influence inflammation, metabolism, and immune function. • Traditional silver fillings contain about 50% mercury, which can release small amounts of mercury vapor over time. • If mercury fillings are removed, it is important that dentists follow safe removal protocols to avoid increased exposure during the process. • Root canals remove the nerve and blood supply from a tooth, leaving dead tissue behind that may harbor bacteria and create ongoing immune stress. • Some biologic dentists recommend removing infected root canal teeth and replacing them with ceramic implants rather than leaving the tooth in place. • Ceramic (zirconia) dental implants are often preferred in biologic dentistry because they are inert and do not conduct electricity like titanium. • Fluoride strengthens enamel but may interfere with thyroid function because it competes with iodine in the body. • Many cavities are not caused by poor brushing but by mineral deficiencies and poor nutrient absorption, often linked to gut health. • Low stomach acid or chronic use of acid-blocking medications may reduce mineral absorption and increase the risk of tooth decay. • Hydroxyapatite toothpaste can help remineralize teeth by replacing lost minerals without fluoride. • Gum disease and oral microbiome imbalances are common causes of bad breath. • Simple practices like tongue scraping, oil pulling, and supporting mineral intake can improve oral and overall health. Resources & Links 🌐 Dr. Michelle Jorgensen, DDS Website: https://livingwellwithdrmichelle.com📸 Instagram: https://www.instagram.com/livingwellwithdrmichelle/ 📲 Follow Dr. Cassie Smith & Modern Endocrine 💻 Website:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modern-endocrine.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📸 Instagram:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.instagram.com/modernendocrine_/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🌟 Facebook:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.facebook.com/ModernEndocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📽️ YouTube:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.youtube.com/@modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🕹️ TikTok:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.tiktok.com/@modernendocrine?lang=en⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📰 Newsletter:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://linktr.ee/modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ➡️ Disclaimer:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modernendocrineokc.com/disclaimer-6353⁠

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠<< What if the reason you still feel tired after optimizing hormones is not your hormones at all? In this episode of Hormones, Metabolism, and You, Dr. Cassie Smith sits down with Dr. Terri DeNeui in Destin, Florida during an advanced hormone provider refresher to talk about the most common issue clinicians see after “optimizing hormones”: patients still feel tired, foggy, inflamed, or stuck. They break down why “normal” labs are not the same as optimal, why Free T3 matters, and how deficiencies in vitamin D, B12, and ferritin can block thyroid hormone function and keep symptoms alive. You will also hear how gut inflammation, H. pylori, and chronic acid blockers can sabotage hormone metabolism, why many “side effects” blamed on hormones are actually root-cause problems, and how to spot misinformation about estrogen and testosterone, especially for women. About Dr. Terri DeNeui Dr. Terri DeNeui, DNP, APRN, ACNP-BC, is a board-certified nurse practitioner, nationally recognized speaker, author, and the founder of EvexiPEL® and Evexia Medical. She holds advanced training in hormone replacement, preventive wellness, and functional medicine, and is known for her root-cause approach to optimizing hormones and whole-body health. Through her clinical work and provider education, Dr. DeNeui has helped transform the lives of thousands of patients and trained clinicians across the country. She is also the author of Hormone Havoc, a practical guide that clears up myths and misconceptions about hormones in women and men. Key Topics Covered Why patients can still feel “off” even when hormones look optimized The thyroid lab most clinicians miss: Free T3 Why “normal” lab ranges often reflect a sick population, not optimal health Vitamin D, B12, and ferritin: the hidden drivers behind fatigue, brain fog, and poor thyroid response Ferritin and thyroid hormone: why low ferritin can block hormone function at the cellular level Gut root causes behind low iron: heavy bleeding, hormone metabolism issues, H. pylori, and inflammation Why chronic PPI use can worsen nutrient absorption and hormone conversion Misconceptions about estrogen and cancer, and why metabolism and inflammation matter Misconceptions about testosterone in women, plus why dosing and proper oversight change outcomes Why hormone care works best when you treat the body as a system of systems Resources & Links 🌐 Dr. Terri DeNeui LinkedIn: https://www.linkedin.com/in/terri-deneui/📚 Book: Hormone Havoc: Dispelling the Myths and Misconceptions about Hormones in Women and Men – https://a.co/d/02qh7exW 📲 Follow Dr. Cassie Smith & Modern Endocrine 💻 Website:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modern-endocrine.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📸 Instagram:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.instagram.com/modernendocrine_/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🌟 Facebook:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.facebook.com/ModernEndocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📽️ YouTube:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.youtube.com/@modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🕹️ TikTok:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.tiktok.com/@modernendocrine?lang=en⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📰 Newsletter:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://linktr.ee/modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ➡️ Disclaimer:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modernendocrineokc.com/disclaimer-6353⁠

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠<< In this special 100th episode of Hormones, Metabolism, and You, Dr. Cassie Smith celebrates the milestone with a best-of compilation featuring some of the most downloaded and impactful conversations from the show. Each segment reflects a powerful truth listeners continue to come back to: when you feel off, there is usually a biological reason, and real answers start with understanding the root cause. You will hear highlights from key conversations, including: Tamar Samuels: Debunking common nutrition myths and social media trends, including restrictive “one-food” weight loss approaches and the confusion around anti-diet culture. This segment emphasizes personalized nutrition, metabolic health, and the importance of sustainable habits that support both body composition and long-term health.  Terri DeNeui: A powerful discussion on hormone therapy in your 30s, 40s, and 50s, including the truth about estrogen and cancer risk. This segment breaks down the long-term misunderstanding from the Women’s Health Initiative and explains why timing, personalization, and proper hormone support are critical for brain, heart, bone, and overall longevity. Dr. Bruce Hoffman: A deep dive into chronic fatigue, mitochondrial dysfunction, and the concept of the cell danger response. You will learn why energy production is central to healing and how factors like toxic load, circadian rhythm, sunlight exposure, hydration, and lifestyle habits directly influence mitochondrial health and recovery. Dr. Cassie Smith (Solo): A practical breakdown of thyroid optimization, including ideal functional ranges for TSH, Free T4, Free T3, Reverse T3, and thyroid antibodies. This segment explains why symptoms matter more than standard lab ranges and how inflammation, gut health, stress, and cellular function affect thyroid hormone activity. Dr. Tyna Moore: An insightful conversation on GLP-1 microdosing and peptide therapy beyond weight loss. This segment explores how low-dose GLP-1s can support brain health, inflammation, metabolic function, and longevity, while also highlighting the importance of gut health, hormone balance, and foundational lifestyle habits before using advanced therapies. Together, these listener-favorite moments reinforce the core message of the show: you are not broken, your symptoms are not random, and lasting change happens when you address the biology behind the symptoms. Key Takeaways This special 100th episode highlights a core theme across listener favorites: when symptoms don’t match normal labs, the issue is often deeper biology, not willpower. Sustainable health requires personalized nutrition, strong lifestyle foundations, and attention to real markers, not trends or extremes. Hormone therapy fears are often based on outdated information, thyroid care goes beyond TSH alone, and tools like GLP-1s work best as supportive therapies, not shortcuts. The consistent message throughout is safety-first, root-cause care with the right intervention at the right time. 📲 Follow Dr. Cassie Smith & Modern Endocrine 💻 Website:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modern-endocrine.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📸 Instagram:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.instagram.com/modernendocrine_/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🌟 Facebook:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.facebook.com/ModernEndocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📽️ YouTube:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.youtube.com/@modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🕹️ TikTok:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.tiktok.com/@modernendocrine?lang=en⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📰 Newsletter:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://linktr.ee/modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ➡️ Disclaimer:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modernendocrineokc.com/disclaimer-6353⁠

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠<< What if peptides and GLP-1s are not the problem, but the internet hype is making it impossible to know what is actually safe, effective, and worth your money? In this episode of Hormones, Metabolism, and You, Dr. Cassie Smith sits down with Greg Jones, NMD to cut through the confusion around peptides, GLP-1s, microdosing, stacking, and the next wave of weight loss medications. Dr. Jones explains why lifestyle is the foundation (there is no magic shot), outlines red flags for online prescribing and questionable sourcing, and compares newer multi-agonists like retatrutide with semaglutide and tirzepatide. You will also learn how to manage common issues like nausea, reflux, constipation, fatigue, and plateaus, and why safety-first, individualized care with proper monitoring matters most. Key Takeaways Healing and body composition start with the foundation: nutrition, hydration, sleep, and resistance training Peptides fall into different categories: some affect feedback loops and require more monitoring, others are used more directly by the body GLP-1 dosing should be individualized; aggressive titration increases side effects and long-term risks Retatrutide is a triple agonist (GLP-1, GIP, glucagon) and may increase energy expenditure, but appetite and food noise can vary by person Side effects often improve when diet, alcohol intake, and hydration are addressed Weight loss should be gradual to help preserve lean mass and reduce skin laxity issues Exit strategies should be personalized: taper dose, extend dosing intervals, and keep the habits in place When the shots go away, the habits need to stay Episode Highlights Why the foundation matters: “trash in, trash out” and why sleep plus strength training drive long-term results Red flag checklist for online prescribing: no labs, no check-ins, “not for human use” labeling, and three-month scripts with no monitoring What to monitor with GLP-1s and related therapies, including why baseline labs matter Retatrutide vs tirzepatide vs semaglutide: what is different, what is promising, and what is still evolving Real-world GLP-1 troubleshooting: reflux, constipation, fatigue, nausea, and why microdosing can change tolerance Why plateaus happen and how to adjust safely without overcorrecting Who is at highest risk for muscle loss during fat loss and how to protect lean mass in midlife Growth-hormone-related peptides explained: CJC-1295, ipamorelin, tesamorelin, and what realistic goals look like Why “stacks” can be risky, when combinations may be acceptable, and why dosing flexibility matters Lightning round: the biggest plateau driver, perimenopause myths, and the single best habit for preserving muscle Connect with Greg Jones, NMD🌐 Website: https://enovativewellness.com/dr-greg-jones/💼 LinkedIn: https://www.linkedin.com/in/drgregjones/ 📲 Follow Dr. Cassie Smith & Modern Endocrine 💻 Website:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modern-endocrine.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📸 Instagram:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.instagram.com/modernendocrine_/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🌟 Facebook:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.facebook.com/ModernEndocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📽️ YouTube:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.youtube.com/@modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🕹️ TikTok:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.tiktok.com/@modernendocrine?lang=en⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📰 Newsletter:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://linktr.ee/modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ➡️ Disclaimer:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modernendocrineokc.com/disclaimer-6353⁠

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠<< What if perimenopause is not your body breaking down, but your body revealing exactly what it needs to function better? In this episode of Hormones, Metabolism, and You, Dr. Cassie Smith sits down with Bria Gadd, known as The Period Whisperer, to reframe perimenopause as a powerful turning point rather than a decline. They discuss why symptoms like fatigue, sleep disruption, anxiety, stubborn weight gain, cravings, and loss of motivation often reflect an energy deficit and accumulated “health debt,” not a lack of discipline. You will learn how years of stress, overtraining, underfueling, and pushing through exhaustion can create survival mode physiology, why traditional diet and fitness strategies often stop working in midlife, and how small shifts in recovery, nourishment, gut health, and thyroid support can help restore your baseline so your body can feel safe enough to regulate again. Key Takeaways Perimenopause symptoms often reflect accumulated stress and energy depletion rather than sudden hormonal failure The “Perimenopause Gift” is your body signaling that current habits are no longer sustainable Health debt builds over time when stress, under-recovery, and under-fueling exceed your body’s capacity When the body is in survival mode, it may hold weight, increase cravings, and slow metabolism More intensity in workouts or stricter dieting often increases stress hormones and worsens symptoms Recovery, mobility, walking, and nervous system support often need to come before high-intensity training Gut health plays an important role in hormone metabolism, nutrient absorption, and inflammation balance Thyroid symptoms are often overlooked, and a full thyroid panel may be necessary when symptoms persist Food noise and sugar cravings can signal energy deficiency, not lack of willpower Sustainable progress comes from rebuilding energy and resilience rather than pushing harder Episode Highlights Why many women feel like their body “changed the rules overnight” during perimenopause The energy supply vs. energy demand model and how it affects hormones, metabolism, and mood How years of high stress, perfectionism, and overperformance contribute to midlife hormone struggles Why strength training should be supported with adequate fuel, recovery, and nervous system balance The connection between gut health and proper estrogen clearance Early signs of thyroid dysfunction that are often dismissed as “normal aging” Simple daily habits that help rebuild baseline energy, including hydration, walking after meals, and intentional rest Why joy, presence, and reducing pressure can improve physiology, not just mindset Bria’s practical framework for getting out of health debt and restoring long-term metabolic resilience   Connect with Bria Gadd 🌐 Website: https://www.briatheperiodwhisperer.com/🔗 LinkedIn: https://www.linkedin.com/in/bria-gadd/📸 Instagram: https://www.instagram.com/bria_period_whisperer/🎧 Podcast: The Period Whisperer 📲 Follow Dr. Cassie Smith & Modern Endocrine 💻 Website:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modern-endocrine.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📸 Instagram:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.instagram.com/modernendocrine_/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🌟 Facebook:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.facebook.com/ModernEndocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📽️ YouTube:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.youtube.com/@modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🕹️ TikTok:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.tiktok.com/@modernendocrine?lang=en⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📰 Newsletter:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://linktr.ee/modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ➡️ Disclaimer:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modernendocrineokc.com/disclaimer-6353⁠

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠<< What if chronic illness protocols stall not because you are doing something wrong, but because your body does not feel safe enough to heal? In this episode of Hormones, Metabolism, and You, Dr. Cassie Smith sits down with Dr. Jabin Moore to unpack why so many chronic illness protocols stall even when you are doing “everything right.” They explain how the brain prioritizes survival over repair when the body does not feel safe, and how stress, trauma, mold, Lyme, infections, and gut dysfunction can run the same threat pathways in the body. You will hear the unforgettable “$100 energy bill” metaphor, learn why detox can backfire when the nervous system is dysregulated, and get practical ways to create real safety in your environment and your biology so healing can finally stick. Key Takeaways Healing does not happen when your nervous system is stuck in fight or flight Safety is biological, not just emotional, and it shapes detox, digestion, hormones, and immune function The “$100 energy bill” explains why chronic illness creates daily energy debt and no healing margin Toxins, infections, and trauma can activate overlapping inflammatory and survival pathways You often need a two-pronged approach: calm the brain while clearing the body More protocols are not always better; too much “good” can overload an already depleted system Start with the basics: safe air, safe water, safe food, then regulate the nervous system Simple nervous system resets can work, even five minutes of stillness and nature exposure Protein matters because low protein can worsen stress physiology and recovery capacity A sustainable plan protects your energy instead of burning it all on performance or perfection Episode Highlights Why the brain can block detox, immune regulation, digestion, and cellular repair when it senses threat Mold, Lyme, PTSD, chronic stress, and gut issues: why they can “speak the same language” in the body The detox myth: you cannot force clearing without first shifting out of threat mode How perfectionism and people-pleasing can drain energy and slow recovery The difference between living in a safe environment and actually feeling safe in it What nervous system work can look like in real life, including limbic retraining tools Dr. Moore’s practical framework: safe environment, safe feeling, then advanced protocols Connect with Dr. Jabin Moore 🌐 Facebook: https://www.facebook.com/redefiningwellnesskc 📸 Instagram: https://www.instagram.com/drjabanmoore/ 🎵 TikTok: https://www.tiktok.com/@drjabanmoore_ ▶️ YouTube: http://www.youtube.com/@DrJabanMoore 📲 Follow Dr. Cassie Smith & Modern Endocrine 💻 Website:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modern-endocrine.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📸 Instagram:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.instagram.com/modernendocrine_/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🌟 Facebook:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.facebook.com/ModernEndocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📽️ YouTube:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.youtube.com/@modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🕹️ TikTok:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.tiktok.com/@modernendocrine?lang=en⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📰 Newsletter:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://linktr.ee/modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ➡️ Disclaimer:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modernendocrineokc.com/disclaimer-6353⁠

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠<< What if brain fog, bloating, exhaustion, and hormonal chaos are not separate problems, but signals of one shared root issue? In this episode of Hormones, Metabolism, and You, Dr. Cassie Smith is joined by returning guest Dr. Shivani Gupta, Ayurvedic practitioner, turmeric researcher, and author of The Inflammation Code. Together, they explore how chronic inflammation quietly disrupts gut health, hormone metabolism, sleep, mood, and energy, especially during perimenopause and menopause. Dr. Gupta explains how ancient Ayurvedic principles align with modern functional medicine, offering practical, non-diet strategies to support digestion, estrogen metabolism, circadian rhythms, and nervous system balance. This conversation focuses on working with the body rather than against it, using daily rhythms, simple rituals, and gut-forward practices to support long-term resilience at every stage of life. Key Topics Covered How chronic inflammation can drive brain fog, bloating, fatigue, and hormonal symptoms The gut–hormone axis and why digestion is central to estrogen metabolism and mood Ayurvedic “digestive fire” (agni) and how modern habits weaken it Why perimenopause and menopause represent a Vata (air and ether) phase of life Early signs of hormonal transition beyond hot flashes, including anxiety, dryness, and sleep disruption How circadian rhythms influence inflammation, hormone balance, and metabolic health Food-first strategies to support estrogen metabolism and reduce bloating Why how and when you eat may matter as much as what you eat The role of gut testing and microbiome balance in long-term healing Super spices as medicine: turmeric, ginger, cumin, coriander, and fennel Why healing does not require extreme diets or rigid routines Building personalized, sustainable self-care rituals that actually stick Key Takeaways Chronic inflammation often connects gut symptoms, hormone imbalance, fatigue, and brain fog Perimenopause and menopause represent a natural shift that requires more grounding and rhythm, not more pushing Gut health plays a central role in estrogen metabolism, mood, and overall resilience Circadian alignment supports inflammation reduction and nervous system balance Small, consistent rituals are often more powerful than complex protocols Spices like turmeric and ginger can support digestion and inflammation when used consistently Healing is individualized and works best when aligned with your body’s natural rhythms Resources & Links 🌐 Website: https://www.shivanigupta.com 📘 Book: The Inflammation Code (Hay House, February 2026)https://www.theinflammationcode.com 🎙️ Fusionary Health Podcast 📲 Instagram: https://instagram.com/dr.shivanigupta 📘 Facebook: https://www.facebook.com/theshivanigupta ▶️ YouTube: https://www.youtube.com/@dr.shivanigupta 📲 Follow Dr. Cassie Smith & Modern Endocrine 💻 Website:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modern-endocrine.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📸 Instagram:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.instagram.com/modernendocrine_/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🌟 Facebook:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.facebook.com/ModernEndocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📽️ YouTube:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.youtube.com/@modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🕹️ TikTok:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.tiktok.com/@modernendocrine?lang=en⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📰 Newsletter:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://linktr.ee/modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ➡️ Disclaimer:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modernendocrineokc.com/disclaimer-6353⁠

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠<< Doing Everything Right but Still Not Losing Weight? - The Shocking Truth About Midlife Metabolism - Learn How Hormones and Peptides Can Finally Unlock Fat Loss Without More Willpower If you feel like you are eating clean, working out, staying consistent, and your body still will not respond, you are not alone. In this episode, Dr. Cassie Smith sits down with Dr. Aleksandra Gajer, M.D., to explore why weight loss resistance often shows up in midlife and why it is rarely about willpower. They unpack how hormones, sleep, stress, inflammation, and insulin resistance can combine to slow progress, and how peptides can be used as strategic tools when they are properly prescribed, sourced, and monitored. You will also hear a practical breakdown of peptide categories, plus an important safety conversation about avoiding online sourcing and quick clinic prescribing. Key Topics Covered Why traditional dieting often fails for high achieving women in midlife How shifting hormones can influence insulin resistance, metabolism, and body composition The role inflammation can play in fatigue, weight gain, and brain fog Why real food fundamentals still matter even with advanced therapies What peptides are and how they differ from typical medications in the body A simple framework: five peptide categories used in clinical practice Metabolic peptides: GLP 1 therapies, MOTS c, and growth hormone promoting peptides Recovery and inflammation peptides: BPC 157 and the use of KPV for gut and immune balance Cognitive peptides discussed: Selank and Semax, plus sleep support with DSIP Longevity focused peptides: Epitalon, plus discussion of NAD and SS 31 Aesthetic peptide overview: GHK Cu and why formulation and tolerability matter Why peptide stacks can be less effective and harder to troubleshoot The importance of medical oversight, safe sourcing, and individualized dosing Free lever for better health: sleep and boundaries around screens Connect with Dr. Aleksandra Gajer, M.D Website: https://thegajerpractice.com/ LinkedIn: https://www.linkedin.com/in/aleksandra-gajer-md/ 📲 Follow Dr. Cassie Smith & Modern Endocrine 💻 Website:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modern-endocrine.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📸 Instagram:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.instagram.com/modernendocrine_/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🌟 Facebook:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.facebook.com/ModernEndocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📽️ YouTube:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.youtube.com/@modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🕹️ TikTok:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.tiktok.com/@modernendocrine?lang=en⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📰 Newsletter:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://linktr.ee/modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ➡️ Disclaimer:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modernendocrineokc.com/disclaimer-6353⁠

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠<< What if your lingering thyroid and hormone symptoms aren’t a lab problem at all, but a gut inflammation issue hiding beneath “normal” results? In this episode of Hormones, Metabolism, and You, Dr. Cassie Smith sits down with holistic nutritionist and physician consultant Josh Dech to explore a core idea many patients never hear: your thyroid and hormone symptoms may be driven by hidden gut inflammation, even when labs look “normal.” Josh explains how gut dysfunction can interfere with hormone signaling, disrupt metabolism, and fuel chronic fatigue, brain fog, and stubborn symptoms. They also discuss common root drivers like toxins, infections, nutrient deficiencies, poor sleep, and chronic stress, plus practical steps to support healing without extreme protocols. Key Topics Covered Why thyroid and hormone symptoms can persist even with “normal” lab results How gut inflammation can block hormone signaling and contribute to fatigue and brain fog Gut health on a spectrum: from mild symptoms to severe inflammatory conditions The “why” behind symptoms vs. labels and diagnoses Mold and environmental exposures as potential hidden drivers for some people The “three buckets” framework: toxins, microbes, and deficiencies The role of sleep, stress, and lifestyle in gut and immune function Why some “healthy” foods can still be personal triggers for certain individuals Supporting drainage and detox pathways as part of recovery Simple, sustainable steps for improving gut and overall health About the Guest Josh Dech is a Holistic Nutritionist and Physician Consultant specializing in Crohn’s disease, ulcerative colitis, and severe IBS. He is known for helping reverse over 400 cases of Crohn’s and colitis through a root-cause, holistic approach to gut health, conditions long considered irreversible within conventional care. Josh has worked alongside some of the world’s most respected medical professionals and has become a trusted educator in the field of digestive and autoimmune health. He hosts a globally ranked top 2 percent podcast, has appeared on international television, and currently serves as a medical lecturer for Priority Health Academy. Today, Josh focuses on educating both physicians and the public on integrative, evidence-informed strategies for healing chronic digestive diseases and restoring long-term gut health. Connect with Josh Dech Facebook: https://www.facebook.com/JoshDechInstagram: https://www.instagram.com/joshdech.health/YouTube: https://www.youtube.com/@joshdech 📲 Follow Dr. Cassie Smith & Modern Endocrine 💻 Website:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modern-endocrine.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📸 Instagram:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.instagram.com/modernendocrine_/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🌟 Facebook:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.facebook.com/ModernEndocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📽️ YouTube:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.youtube.com/@modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🕹️ TikTok:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.tiktok.com/@modernendocrine?lang=en⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📰 Newsletter:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://linktr.ee/modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ➡️ Disclaimer:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modernendocrineokc.com/disclaimer-6353⁠

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠<< What if weight loss isn’t about discipline, motivation, or trying harder, but about understanding what your hormones are actually doing? In this powerful New Year mash-up episode of Hormones, Metabolism, and You, Dr. Cassie Smith brings together the most impactful insights from three standout conversations to explain why traditional diets fail so many women and what truly supports sustainable weight loss. Drawing from expert guidance by Tamar Samuels, Shana Hussin, and Terri DeNeui, this episode reframes weight gain as a hormonal and metabolic signal, not a personal failure. Listeners will learn how stress, gut health, insulin resistance, PCOS, thyroid dysfunction, and age-related hormone shifts quietly sabotage fat loss, and why fasting, restriction, and one-size-fits-all diets often make things worse. This episode is especially for women in their 30s, 40s, and 50s who feel stuck, exhausted, and frustrated despite doing “all the right things.” Episode Highlights Why weight gain is often driven by hormones, not willpower How cortisol, leptin, insulin, and thyroid hormones block fat loss What really changes hormonally in your 30s, 40s, and 50s Why testosterone and progesterone decline earlier than most women realize The truth about fasting and why it backfires for stressed women How gut health directly affects metabolism and hormone balance Why PCOS, thyroid issues, and insulin resistance require targeted nutrition How restrictive diets and under-eating damage hormones long term Why protein needs increase with age and how much women actually need Why the scale lies and what markers matter more than weight Key Topics Covered It’s Not Your Fault: Understanding Hormone Shifts Hormonal changes begin earlier than menopause Testosterone loss affects muscle, mood, metabolism, and energy Progesterone decline impacts sleep, stress tolerance, and fat storage Weight gain is often a biological response, not a behavior issue The Hidden Conditions Blocking Weight Loss PCOS, thyroid dysfunction, and insulin resistance explained simply How cortisol and chronic stress stop fat burning Why leptin resistance develops from dieting and fasting Why blood sugar balance matters more than calorie counting Food as Medicine, Not Punishment Why personalized nutrition beats rigid diet rules Protein targets for women as they age The real role of carbs and fats in hormone health Why meal timing and eating enough matters Lifestyle Changes That Actually Work Circadian rhythm alignment and stress reduction Gut health as the foundation of hormone metabolism Why extreme fasting, overtraining, and restriction do harm Root-cause care vs symptom suppression Final Takeaway This New Year, the answer isn’t another diet, cleanse, or restriction plan. Sustainable weight loss happens when you: Support your hormones Heal your gut Eat enough of the right foods Reduce stress Stop fighting your biology Your body isn’t broken. It’s communicating. 📲 Follow Dr. Cassie Smith & Modern Endocrine 💻 Website:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modern-endocrine.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📸 Instagram:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.instagram.com/modernendocrine_/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🌟 Facebook:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.facebook.com/ModernEndocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📽️ YouTube:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.youtube.com/@modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🕹️ TikTok:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.tiktok.com/@modernendocrine?lang=en⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📰 Newsletter:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://linktr.ee/modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ➡️ Disclaimer:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modernendocrineokc.com/disclaimer-6353⁠

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠<< What if your hormone symptoms aren’t a hormone problem at all, but warning signs of deeper toxic, gut, and immune stress your body has been carrying for years? In this powerful episode of Hormones Metabolism in You, Dr. Cassie Smith sits down with Dr. Kelly K. McCann, MD, to unpack why hormone symptoms like fatigue, weight gain, brain fog, mood changes, and stubborn metabolic dysfunction are often not hormone problems at all. Instead, Dr. McCann explains how these symptoms are signals pointing to deeper root causes such as environmental toxin exposure, mold, gut dysfunction, immune dysregulation, and chronic inflammation. Together, they challenge the conventional approach of treating hormones in isolation and highlight why normal lab results do not always mean the body is functioning optimally. This conversation explores how everyday exposures from water contamination and plastics to non-stick cookware, pesticides, and personal care products can silently disrupt thyroid function, metabolism, and hormone signaling. The episode also dives into the critical gut hormone immune connection, mold related illness, nutrient depletion, mitochondrial dysfunction, and the concept of the cell danger response. About the Guest Dr. Kelly K. McCann, MD is a board certified physician trained in internal medicine and pediatrics, with advanced training in integrative and functional medicine. Her work focuses on the impact of environmental exposures on human health, including mold illness, chemical toxicity, chronic infections, immune dysregulation, and mast cell activation syndrome. Dr. McCann specializes in treating complex chronic illness by addressing root causes such as toxic burden, gut permeability, mitochondrial dysfunction, and nervous system imbalance. She is the founder of The Spring Center in Southern California and provides care to patients across multiple states. She also teaches and writes extensively on the intersection of environment, immunity, hormones, and healing. Key Topics Covered Why hormone symptoms are messengers, not the root problem Environmental toxins and their impact on thyroid and hormone signaling Mold exposure and its role in chronic illness and metabolic dysfunction The gut hormone immune axis and why gut health is inseparable from hormone health How plastics, PFAS, pesticides, and contaminated water disrupt endocrine function Food related mold and toxin exposure, including grains, corn, and peanuts Heavy metals, mercury accumulation, and bioaccumulation in the body Why many patients struggle despite “normal” lab results Critical labs often missed in conventional care, including thyroid conversion markers The role of mitochondrial dysfunction and the cell danger response Chronic stress, trauma, and nervous system dysregulation in hormone imbalance Why perimenopause often reveals accumulated toxic burden Small, practical steps to reduce toxic load and support healing Links & Resources:  Dr. Kelly K. McCann, MD 🔗 Official Websitehttps://drkellymccann.com/ 🔗 The Spring Centerhttps://thespringcenter.com/ 🔗 LinkedIn Profilehttps://www.linkedin.com/in/dr-kelly-mccann/ 📲 Follow Dr. Cassie Smith & Modern Endocrine 💻 Website:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modern-endocrine.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📸 Instagram:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.instagram.com/modernendocrine_/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🌟 Facebook:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.facebook.com/ModernEndocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📽️ YouTube:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.youtube.com/@modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🕹️ TikTok:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.tiktok.com/@modernendocrine?lang=en⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📰 Newsletter:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://linktr.ee/modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ➡️ Disclaimer:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modernendocrineokc.com/disclaimer-6353⁠

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠<< What if many hormone, thyroid, and energy problems come down to a single overlooked molecule your body is quietly running out of? In this episode of Hormones Metabolism in You, Dr. Cassie Smith sits down with nitric oxide expert Dr. Nathan Bryan to explore why nitric oxide is one of the most overlooked yet essential molecules in human health. Together, they unpack nitric oxide’s powerful role in hormone signaling, thyroid function, gut motility, immune defense, blood flow, and mitochondrial energy production. Dr. Bryan explains how nitric oxide deficiency can contribute to fatigue, hormone resistance, insulin resistance, poor circulation, and chronic inflammation, even when labs appear “normal.” They also discuss how modern lifestyle factors such as aging, chronic stress, poor diet, fluoride exposure, antiseptic mouthwash use, and long term antacid use can significantly impair nitric oxide production. Most importantly, this conversation offers practical, science backed strategies listeners can apply immediately to support nitric oxide levels and improve overall hormone health, energy, and longevity. About the Guest Dr. Nathan Bryan holds a Bachelor of Science in Biochemistry from the University of Texas at Austin and earned his doctoral degree from Louisiana State University School of Medicine in Shreveport, where he received the Dean’s Award for Excellence in Research. He completed postdoctoral training as a Kirschstein Fellow at Boston University School of Medicine in the Whitaker Cardiovascular Institute. In 2006, Dr. Bryan joined the faculty at the University of Texas Health Science Center at Houston under the recruitment of Nobel Laureate Dr. Ferid Murad. With over two decades of experience in nitric oxide research, he has made significant contributions to the field, resulting in numerous US and international patents and clinically impactful technologies. Dr. Bryan is also a successful entrepreneur and Founder and CEO of Nitric Oxide Innovations, LLC, where he continues to advance nitric oxide based therapies and molecular medicine worldwide. Key Topics Covered What nitric oxide is and why it is essential for human health How nitric oxide influences hormone signaling and receptor sensitivity The connection between nitric oxide and thyroid function Nitric oxide’s role in gut motility, digestion, and the oral microbiome How nitric oxide supports immune defense and inflammation control Mitochondrial energy production and cellular oxygen delivery Why nitric oxide production declines with age How stress, poor diet, and environmental exposures impair nitric oxide The impact of fluoride, antiseptic mouthwash, and antacids on nitric oxide production Common symptoms associated with nitric oxide deficiency How impaired blood flow affects hormone delivery and tissue response Links & Resources Website: https://drnathansbryan.com/LinkedIn: https://www.linkedin.com/in/drnathansbryan Nitric Oxide Education:https://www.n1o1.com/https://www.no2u.com/https://www.nitricoxideinnovations.com/ Shop N1O1 Products: https://www.awin1.com/cread.php?awinmid=115399&awinaffid=2702698 📲 Follow Dr. Cassie Smith & Modern Endocrine 💻 Website:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modern-endocrine.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📸 Instagram:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.instagram.com/modernendocrine_/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🌟 Facebook:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.facebook.com/ModernEndocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📽️ YouTube:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.youtube.com/@modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🕹️ TikTok:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.tiktok.com/@modernendocrine?lang=en⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📰 Newsletter:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://linktr.ee/modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ➡️ Disclaimer:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modernendocrineokc.com/disclaimer-6353⁠

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠<< What if the biggest problem in modern medicine isn’t a lack of treatments, but a lack of training in nutrition, gut health, and root cause care? In this episode, Dr. Cassie Smith welcomes back Dr. Johnny Hadac, now a family medicine resident, to reflect on how his medical training has evolved and where traditional healthcare continues to fall short. Together, they unpack the realities of residency, the lack of meaningful nutrition and gut health education in medical training, and why chronic disease cannot be solved without addressing inflammation, hormones, and the gut. Dr. Hadac shares what he has learned during his first months of residency, how functional medicine principles have shaped his approach to patient care, and why proactive, relationship based medicine leads to better outcomes. The conversation also explores the broken insurance driven healthcare system, the importance of provider education, and how social media can help close the knowledge gap. They also dive into Dr. Hadac’s bestselling cookbook, which combines practical, affordable recipes with extensive education on gut health, insulin resistance, fiber, and hormone balance. This episode offers hope for the future of medicine and practical tools for patients and providers alike. About the Guest Dr. Johnny Hadac is a family medicine resident, physician, certified nutritionist, and culinary medicine specialist. He is the founder of Total Weight Loss and Muscle Dummies, a global health community with over two million followers focused on affordable, science based nutrition and lifestyle habits. Dr. Hadac is a bestselling cookbook author and app developer who blends medical science with real world practicality. His work centers on gut health, insulin resistance, metabolic health, and sustainable weight loss through high fiber, high protein, whole food nutrition. Through social media, education, and clinical practice, he is helping reshape how people understand health, food, and disease prevention. Key Topics Covered What residency is really like and how medical education is evolving Major gaps in nutrition and gut health training for physicians Why gut health is foundational to hormone balance and chronic disease The role of fiber, fermented foods, and inflammation in metabolic health How functional medicine principles improve patient outcomes Challenges of insurance driven healthcare systems Direct primary care and proactive medicine models Social media as a tool for patient and provider education Insulin resistance and metabolic dysfunction Practical, accessible nutrition strategies for long term health Connect with Dr. Johnny Hadac LinkedIn: https://www.linkedin.com/in/johnny-hadac-6a38aa126/Instagram: https://www.instagram.com/drjohnnyhadac/ 📲 Follow Dr. Cassie Smith & Modern Endocrine 💻 Website:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modern-endocrine.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📸 Instagram:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.instagram.com/modernendocrine_/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🌟 Facebook:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.facebook.com/ModernEndocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📽️ YouTube:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.youtube.com/@modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🕹️ TikTok:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.tiktok.com/@modernendocrine?lang=en⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📰 Newsletter:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://linktr.ee/modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ➡️ Disclaimer:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modernendocrineokc.com/disclaimer-6353⁠

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠<< What if the biggest breakthrough in women’s health this decade is the long overdue reversal of a warning that never should have existed in the first place? In this timely episode, Dr. Cassie Smith sits down with hormone expert and healthcare reform advocate Dr. Terri DeNeui, DNP, APRN, ACNP-BC to unpack the FDA’s landmark decision to remove the black box warning from estrogen containing HRT. For the first time in over twenty years, science and policy finally align, creating safer and more accessible options for millions of women. Dr. Cassie and Dr. Terri break down what the original research actually showed, how estrogen became unfairly feared, and why the updated guidelines are long overdue. They explore the benefits of estrogen, progesterone, and testosterone for women, clearing up misconceptions and highlighting the need for better hormone education among providers and patients. With clinical insights and decades of experience, this episode reveals the truth about hormone therapy, why women have suffered needlessly for two decades, and how the removal of the black box warning can reshape the future of women's health.   About the Guest Dr. Terri DeNeui, DNP, APRN, ACNP-BC is a board certified Adult Acute Care Nurse Practitioner, entrepreneur, Chief Science Officer, and leading voice in healthcare reform. She serves on the Executive Committee of the America First Policy Institute and the America First Women’s Initiative, contributing to national healthcare policy. A Summa Cum Laude graduate of the University of Texas at Arlington, Dr. DeNeui holds the Doctor of Nursing Practice degree. She is the Founder of EVEXIAS Medical Centers and EVEXIAS Health Solutions, and creator of the EvexiPEL Method of hormone optimization, used globally and supported by outcomes research. She is also lead teaching faculty for the A4M World Congress on Anti Aging Medicine. Her published work includes the peer reviewed article Best Practices in Care for the Menopausal Patient and the bestselling book Hormone Havoc: Dispelling the Myths and Misconceptions about Hormones in Women and Men.   Key Topics Covered What the FDA’s black box removal means for women How the Women’s Health Initiative was misinterpreted Estrogen’s role in brain, heart, bone, gut, metabolic, and vaginal health How fear based messaging led to unnecessary suffering Benefits and safety of micronized progesterone Why testosterone is essential for women’s mood, libido, muscle, and cognition Early testosterone decline and how it affects daily life Hormones, intimacy, and relationship well being Why hormone therapy requires gut health evaluation and individualized dosing Provider education gaps and self advocacy for women Recognizing hormone decline across the lifespan Why better policy and access to hormone therapy are urgently needed Connect with Dr. Terri DeNeui Instagram: https://www.instagram.com/drterrideneui/ Facebook: https://www.facebook.com/DrTerriDeNeui/LinkedIn: https://www.linkedin.com/in/terri-deneuiWebsite: https://www.evexias.comPodcast: https://podcasts.apple.com/us/podcast/the-dr-terri-show/id1757438909Email: terri.deneui@evexias.com Phone: (214) 202-4727 📲 Follow Dr. Cassie Smith & Modern Endocrine 💻 Website:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modern-endocrine.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📸 Instagram:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.instagram.com/modernendocrine_/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🌟 Facebook:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.facebook.com/ModernEndocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📽️ YouTube:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.youtube.com/@modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🕹️ TikTok:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.tiktok.com/@modernendocrine?lang=en⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📰 Newsletter:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://linktr.ee/modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ➡️ Disclaimer:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modernendocrineokc.com/disclaimer-6353⁠

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠<< What if the key to reversing Graves disease starts with uncovering the hidden triggers your thyroid has been reacting to all along? In this information rich episode, Dr. Cassie Smith sits down with functional medicine practitioner and thyroid expert Dr. Eric Osansky to break down the realities of Graves disease and hyperthyroidism. They explore why diagnosis is often delayed, what truly drives autoimmune thyroid conditions, and how gut health, nutrient deficiencies, infections, stress, and environmental toxins all influence thyroid function. Dr. Osansky also shares his personal remission journey and offers practical guidance, testing recommendations, and natural treatment options. This episode is essential for anyone navigating Graves disease, hyperthyroidism, or persistent thyroid symptoms and searching for a root cause approach. About the Guest Dr. Eric Osansky is a functional medicine practitioner with more than 15 years of clinical experience in chiropractic care, nutrition, and autoimmune thyroid health. After reversing his own Graves disease in 2009, he dedicated his career to helping others heal naturally. He is the author of Natural Treatment Solutions for Hyperthyroidism and Graves Disease, Hashimoto’s Triggers, and The Hyperthyroid Healing Diet, and hosts the Save My Thyroid podcast. He holds a Master’s degree in Human Nutrition and Functional Medicine and advanced certifications in nutrition and herbal therapy. Key Topics Covered How Graves disease differs from hypothyroidism and why hyperthyroidism is often misunderstood The environmental, immune, and lifestyle triggers that drive autoimmune thyroid disease Stress, infections, toxins, and overtraining as common contributors How gluten, corn, dairy, and high sodium intake influence leaky gut and autoimmunity The thyroid gut connection and how dysbiosis, H. pylori, and nutrient malabsorption affect thyroid function Essential nutrients for healthy thyroid hormone production and conversion The most important labs thyroid patients should request How H. pylori, viruses, mold, and stealth infections impact autoimmunity Conventional treatments including methimazole, PTU, beta blockers, and when they are necessary Natural therapies such as bugleweed, motherwort, lemon balm, selenium, and L carnitine The role of LDN and why results vary in Graves disease Why healing requires sleep, stress management, gut repair, movement, and nutrient optimization How to advocate for your health when providers overlook root causes Connect with Dr. Eric Osansky Facebook: https://www.facebook.com/NaturalThyroidTreatment/YouTube: https://www.youtube.com/@NaturalThyroidDoctorInstagram: https://www.instagram.com/drericosansky/Website: https://savemythyroid.com 📲 Follow Dr. Cassie Smith & Modern Endocrine 💻 Website:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modern-endocrine.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📸 Instagram:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.instagram.com/modernendocrine_/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🌟 Facebook:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.facebook.com/ModernEndocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📽️ YouTube:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.youtube.com/@modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🕹️ TikTok:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.tiktok.com/@modernendocrine?lang=en⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📰 Newsletter:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://linktr.ee/modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ➡️ Disclaimer:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modernendocrineokc.com/disclaimer-6353⁠

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠<< What if the real answers to your midlife hormone struggles are not in a pill, but in understanding the deeper connections between your thyroid, metabolism, and the way your body changes over time? In this powerhouse mashup episode, Dr. Cassie Smith brings together two of the most outspoken and experienced voices in functional medicine: McCall McPherson, thyroid expert and founder of Modern Thyroid Clinic, and Dr. Tyna Moore, a naturopathic physician and metabolic health disruptor. Together, they unpack the complex hormonal shifts women experience—especially during perimenopause and menopause—and share real-world strategies to reclaim health, energy, and vitality. From GLP-1 medications to progesterone deficiency, thyroid misdiagnosis to strength training, this episode covers the most pressing questions women are asking today. You’ll hear personal insights, clinical wisdom, and evidence-based tools for navigating hormone changes, gut issues, inflammation, and mental health with clarity and confidence. 👤 About the Guests McCall McPherson is the founder of Modern Thyroid Clinic and Thyroid Nation, a TEDx speaker, physician assistant, and a thyroid warrior herself. Her mission is to end the suffering of millions with thyroid disorders through expert care, patient advocacy, and empowering education. Dr. Tyna Moore is a licensed Naturopathic Physician and Chiropractor specializing in resilient metabolic health, regenerative medicine, and clinical strength training. She's also the host of The Dr. Tyna Show and a strong advocate for women’s health and muscle-centric aging. 🔑 Key Topics Covered ✅ The truth about GLP-1s like semaglutide and tirzepatide—and what microdosing really means ✅ When to consider hormone therapy and why most women need progesterone earlier than expected ✅ Why muscle is your best metabolic and hormone-supporting organ ✅ The thyroid–estrogen connection and how hormone shifts during menopause impact thyroid function ✅ How GLP-1s can expose hidden dysfunctions like gut dysbiosis and low estrogen ✅ Why low progesterone may be behind your irritability, sleep issues, and anxiety ✅ The importance of comprehensive thyroid testing (FT3, FT4, RT3) and individualized care ✅ Gut–hormone–brain axis: how estrogen and thyroid hormones influence mood and digestion ✅ Alcohol and inflammation: the honest truth about even “just one glass” ✅ Empowering women to advocate for their health in a broken system ✅ The generational shift in how women approach midlife and aging 📲 Follow Dr. Cassie Smith & Modern Endocrine 💻 Website:⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modern-endocrine.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📸 Instagram:⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.instagram.com/modernendocrine_/⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🌟 Facebook:⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.facebook.com/ModernEndocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📽️ YouTube:⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.youtube.com/@modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🕹️ TikTok:⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.tiktok.com/@modernendocrine?lang=en⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📰 Newsletter:⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://linktr.ee/modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠ ➡️ Disclaimer:⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modernendocrineokc.com/disclaimer-6353⁠

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠<< What if the key to healing your hormones has been hidden in your thought patterns all along? In this transformational episode, Dr. Cassie Smith sits down with renowned clinical neuroscientist and communication pathologist Dr. Caroline Leaf to explore how mental health and hormonal health are deeply intertwined. They dive into the science of neuroplasticity—our brain’s ability to rewire itself—and how harnessing this power can help women break free from anxiety, depression, and hormonal imbalances. Dr. Leaf introduces her 5-step Neurocycle™ process, explains why anxiety and depression are not diseases but signals, and shows how rewiring our thought patterns can improve everything from thyroid function to weight loss. If you've ever struggled with chronic stress, burnout, mood swings, or stubborn hormone issues, this episode offers hope, science, and practical tools to help you heal from the inside out.   👤 About the Guest: Dr. Caroline Leaf is a clinical neuroscientist, communication pathologist, bestselling author of 19 books, and host of the award-winning podcast Cleaning Up the Mental Mess. With over 50 million downloads and a global following, Dr. Leaf is a pioneer in the field of mind-brain research and mental health. Her work bridges neuroscience, mental wellness, and functional healing through a holistic lens. 🔗 Website: www.drleaf.com 🎙️ Podcast: Cleaning Up the Mental Mess 📸 Instagram: @drcarolineleaf   🔑 Key Topics Covered: The critical difference between your mind and your brain—and why it matters for healing Understanding neuroplasticity and how thoughts physically rewire your brain and body Why anxiety, depression, and ADHD are not diseases but signals The Neurocycle™: A 5-step process to break toxic thinking and form healthier patterns The 63-day habit rewiring rule (not just 21!) How hormones respond to thought patterns and emotional states The mind-gut-hormone axis and why doctors often overlook it Why mental and emotional trauma can literally reshape your endocrine system The importance of self-directed mind management in chronic illness, burnout, and hormone recovery How to recognize when you're in the “dip” of transformation—and what to do about it 📲 Follow Dr. Cassie Smith & Modern Endocrine 💻 Website:⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modern-endocrine.com/⁠⁠⁠⁠⁠⁠⁠⁠ 📸 Instagram:⁠⁠⁠⁠⁠⁠⁠⁠ https://www.instagram.com/modernendocrine_/⁠⁠⁠⁠⁠⁠⁠⁠ 🌟 Facebook:⁠⁠⁠⁠⁠⁠⁠⁠ https://www.facebook.com/ModernEndocrine⁠⁠⁠⁠⁠⁠⁠⁠ 📽️ YouTube:⁠⁠⁠⁠⁠⁠⁠⁠ https://www.youtube.com/@modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠ 🕹️ TikTok:⁠⁠⁠⁠⁠⁠⁠⁠ https://www.tiktok.com/@modernendocrine?lang=en⁠⁠⁠⁠⁠⁠⁠⁠ 📰 Newsletter:⁠⁠⁠⁠⁠⁠⁠⁠ https://linktr.ee/modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠ ➡️ Disclaimer:⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modernendocrineokc.com/disclaimer-6353⁠

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠<< Could your migraines be less about pain in your head—and more about hidden imbalances in your hormones, gut, and environment? In this episode of Hormones, Metabolism, and You, Dr. Cassie Smith sits down with functional medicine pharmacist Dr. Meg Mill to uncover the surprising root causes of chronic migraines—especially in women navigating hormonal shifts like menstruation, perimenopause, and menopause. Together, they explore how more than 50 potential triggers can fuel migraine symptoms, from dehydration and poor sleep to gut health issues, estrogen dominance, and histamine intolerance. Dr. Mill shares how functional medicine helps uncover these connections and provides a roadmap for lasting relief. They discuss the power of personalized migraine tracking, hormone and gut testing, and targeted protocols to reduce inflammation and rebalance the nervous system. Whether you’ve suffered for years or are newly struggling with hormone-driven headaches, this episode is a must-listen. 💡 Functional migraine solutions are within reach—no endless prescriptions required. 🔑 Key Topics Covered How hormonal shifts during perimenopause and menstruation trigger migraines Why there are 50+ potential migraine triggers—and how to uncover your unique mix Common food triggers: histamine, tyramine, nitrates, sulfites, MSG, and wine Why your environment, stress levels, and even your air quality can worsen migraines The link between estrogen dominance, progesterone deficiency, and mast cell activation The role of gut health, detoxification, and sleep in migraine prevention How histamine intolerance contributes to migraines, fatigue, anxiety, and skin issues The truth about low stomach acid, acid reflux, and poor nutrient absorption Personalized approaches vs. symptom suppression (why journaling matters) When to use testing like the DUTCH test or GI Map for hormones and gut health 👤 About the Guest: Dr. Meg Mill, PharmD, AFMCP Dr. Meg Mill is a functional medicine pharmacist, bestselling author, and host of A Little Bit Healthier podcast. With 20+ years of clinical experience, she helps women around the world resolve migraines, hormonal issues, and histamine-related symptoms. She's the founder of the Radiant Method, which empowers women to regain energy and clarity through root-cause healing. 📍 Learn more: www.megmill.com 🎧 Podcast: A Little Bit Healthier 📲 Follow Dr. Cassie Smith & Modern Endocrine 💻 Website:⁠⁠⁠⁠⁠⁠⁠ https://www.modern-endocrine.com/⁠⁠⁠⁠⁠⁠⁠ 📸 Instagram:⁠⁠⁠⁠⁠⁠⁠ https://www.instagram.com/modernendocrine_/⁠⁠⁠⁠⁠⁠⁠ 🌟 Facebook:⁠⁠⁠⁠⁠⁠⁠ https://www.facebook.com/ModernEndocrine⁠⁠⁠⁠⁠⁠⁠ 📽️ YouTube:⁠⁠⁠⁠⁠⁠⁠ https://www.youtube.com/@modernendocrine⁠⁠⁠⁠⁠⁠⁠ 🕹️ TikTok:⁠⁠⁠⁠⁠⁠⁠ https://www.tiktok.com/@modernendocrine?lang=en⁠⁠⁠⁠⁠⁠⁠ 📰 Newsletter:⁠⁠⁠⁠⁠⁠⁠ https://linktr.ee/modernendocrine⁠⁠⁠⁠⁠⁠⁠ ➡️ Disclaimer:⁠⁠⁠⁠⁠⁠⁠ https://www.modernendocrineokc.com/disclaimer-6353⁠