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ImmunoCAST

Author: Thermo Fisher Scientific

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From medical guidelines and best practices to educational insights on specific disease states, ImmunoCAST is a podcast dedicated to providing healthcare providers of all specialties clinically relevant, easy-to-digest episodes on allergy related topics.
52 Episodes
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This is part 2 of ImmunoCAST, highlighting interesting abstracts presented at the American College of Allergy, Asthma, and Immunology’s 2024 meeting. In this episode, we explore nine allergy-related medical case studies that were showcased and piqued our interest. Tune in and discover some of the fascinating ways allergies may present in your patients and what you can do to optimize your diagnosis and management. From shrimp exposure through breast milk to developing a peanut sensitization from a blood transfusion, you’re not going to want to miss this episode. Episode resources and references available at: https://www.thermofisher.com/phadia/us/en/resources/immunocast/s2e13.html?cid=0ct_3pc_05032024_9SGOV4
ImmunoCAST visited the 2024 American College of Allergy, Asthma, and Immunology meeting and collected some of the most interesting and important research papers which were unveiled during the conference. Whether you’re an allergist or a primary care clinician, tune in to hear some of the most exciting research and insights that are coming out of the field of allergy, including the role of climate change on latex allergy, the role of allergic rhinitis and food allergy on mental health, and much more. Episode resources and references available at https://www.thermofisher.com/phadia/us/en/resources/immunocast/s2e12.html?cid=0ct_3pc_05032024_9SGOV4
With almost half a million followers on Instagram and over 1.3 million followers on TikTok, allergist Dr. Zachary Rubin has built a huge following of users interested in his allergy insights. Tune in as we interview Dr. Rubin to understand the role of a clinician online, best practices for combating online misconceptions, and how he leverages digital platforms to deliver accurate allergy and immunology education. We also get advice on potential ways primary care providers can help optimize allergy care before specialist referrals, as well as some of the pitfalls they should avoid when managing patients with allergies. From social media tips to optimizing your practice, you’re not going to want to miss this episode. Episode resources and references available at https://www.thermofisher.com/phadia/us/en/resources/immunocast/s2e11.html?cid=0ct_3pc_05032024_9SGOV4
Because ethanol is too small of a molecule for the body to make antibodies to, there really is no such thing as an "alcohol allergy," but that doesn't mean patients can't have a reaction to substances found within alcohol. In this episode of ImmunoCAST, we address the clinical challenge of distinguishing between alcohol intolerance and true allergy. Tune in as we explore histamine intolerance, sulfite sensitivity, and ALDH2 deficiency, as well as hidden allergens in alcoholic beverages, the role of alcohol as a cofactor in allergic reactions, and specific allergens found in wine and beer. Discover how to diagnose and manage alcohol-related reactions by learning more about the importance of detailed patient history, specific IgE testing, and the implications of enzyme deficiencies. Episode resources and references available at https://www.thermofisher.com/phadia/us/en/resources/immunocast/s2e10.html?cid=0ct_3pc_05032024_9SGOV4
Halloween presents unique challenges for clinicians managing patients with food allergies. In this episode, to heighten awareness and preparedness, we explore the emotional impact on children with food allergies, who may often feel excluded from Halloween activities, as well as emphasize the importance of an accurate diagnosis using component resolved diagnostic blood tests to help identify exactly what with in an allergen may be causing a reaction. Additionally, we explore strategies for clinicians to help balance safety with inclusion, ensuring that children with food allergies can participate in Halloween festivities without compromising their health. Episode resources and references available at https://www.thermofisher.com/phadia/us/en/resources/immunocast/s2e9.html?cid=0ct_3pc_05032024_9SGOV4
When we picture a patient struggling with respiratory allergies, our mind might immediately jump to spring allergy season. However, fall allergies, while often overlooked, can cause patients to experience reactions just as severe due to the combination of outdoor triggers and viral season. Tune in as we discuss the history of ragweed, its impact on public health, and its connection to oral allergy syndrome. We also dive into the role of outdoor mold as leaves decompose, the impact of flu season, and the importance of managing indoor allergens such as pet dander and dust mites. Listen now and gain helpful tips on how to diagnose, prepare for, and manage patients this fall season. Link to episode resources and references: https://www.thermofisher.com/phadia/us/en/resources/immunocast/s2e8.html?cid=0ct_3pc_05032024_9SGOV4 **Clarification: At 2m12s, the ragweed epidemic Gary is referencing occurred in the 20th century, not the 19th century.
ImmunoCAST welcomes Dr. Michael Benninger, Professor and Former Chair of the Department of Otolaryngology-Head and Neck Surgery in the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, as a guest expert speaker on this special Allergy After Dark episode. With over 200 publications, Dr. Benninger is an expert on respiratory allergies and their impact on sexual function in patients. Tune in to this episode, where Dr. Benninger joins Gary and Luke to discuss the importance of understanding a patient’s allergic triggers and how they may impact a more intimate side of their life. Episode resources and references available at https://www.thermofisher.com/phadia/us/en/resources/immunocast/s2e7.html
Does your patient have a food allergy or intolerance? Celiac disease or wheat allergy? When it comes intolerances vs. allergies, there’s a lot of symptoms overlap. In this episode of ImmunoCAST, we discuss the mechanisms and differences behind IgE-mediated food allergies, autoimmune conditions like celiac disease, and various types of food intolerances, including metabolic, pharmacologic, and toxic reactions. We also dive into the pitfalls of at-home IgG food intolerance tests that patients may use as well as the importance of clinical history and proper diagnostic testing. Tune in for valuable insights to help optimize your diagnosis and patient management of adverse food reactions. Episode resources and references available at https://www.thermofisher.com/phadia/us/en/resources/immunocast/s2e6.html?cid=0ct_3pc_05032024_9SGOV4
Using the Triple Aim framework to dissect the current status of allergy care in America, this episode delves into the per capita cost, population health, and patient experience of care, emphasizing the importance of accurate diagnosis and appropriate referrals. Tune in for insights on improving healthcare efficiency, reducing costs, and enhancing patient outcomes. Don't miss this informative episode designed to help clinicians better serve their patients. Episode resources and references available at https://www.thermofisher.com/phadia/us/en/resources/immunocast/s2e5.html?cid=0ct_3pc_05032024_9SGOV4
Asthma Peak Week is nearly a month away, giving clinicians just enough time to start to help prepare their at-risk patients. Tune into this episode of ImmunoCAST where we break down why in September there is a spike in asthma exacerbations and hospitalizations as well as some tips and insights on how to ensure your patients with asthma are prepared and safe in the coming month. Episode resources and references available at https://www.thermofisher.com/phadia/us/en/resources/immunocast/s2e4.html?cid=0ct_3pc_05032024_9SGOV4
This episode covers some of the more popular theories on ways patients may develop allergies, such as the epithelial barrier hypothesis, hygiene hypothesis, and microbiome theory. From children to older adults, Gary and Luke discuss the prevalence of food and respiratory allergies and how these allergies may present and change over the course of a patient’s life. Tune in to understand how these changes may impact past diagnoses as well as patient management. Episode resources and references available at https://www.thermofisher.com/phadia/us/en/resources/immunocast/s2e3.html?cid=0ct_3pc_05032024_9SGOV4
Whether your patients are Olympians, little league champs, or rec center pros, tune in to discover the fascinating impact that food and respiratory allergies have on athletes. In this episode of ImmunoCAST, Gary and Luke delve into key insights on diagnosing and managing allergies in athletic patients, from examining the prevalence of allergic diseases among Olympians and recreational athletes to unpacking conditions like exercise-induced anaphylaxis. Episode resources and references available at: https://www.thermofisher.com/phadia/us/en/resources/immunocast/s2e2.html?cid=0ct_3pc_05032024_9SGOV4
In this episode of ImmunoCAST, hosts Gary and Luke break down the essentials of tree nut allergen components, focusing on hazelnut, cashew, walnut, and Brazil nut. They highlight the significant prevalence of tree nut allergies and the importance of accurate diagnosis using component-resolved diagnostics. The discussion covers different types of allergen components, such as PR-10 proteins, lipid transfer proteins, and storage proteins, and what they mean for patient care. This episode is designed to help primary care clinicians better understand how to predict the severity of allergic reactions and make informed decisions in managing their patients. An interpretation guide and lab ordering information are also provided to make it easy to apply these insights in practice. Episode resources and references available at: https://www.thermofisher.com/phadia/us/en/resources/immunocast/s2e1.html?cid=0ct_3pc_05032024_9SGOV4
How can primary care clinicians optimize the diagnosis and treatment of stinging insect allergies? Tune into this episode of ImmunoCAST and hear a discussion around allergies to bee, wasp, and fire ant venoms. You’ll learn how testing with allergen components can aid in reaching an accurate diagnosis, the significance of tryptase levels in forecasting severe allergic reactions, as well as how impactful immunotherapy may be when conducted based on accurate diagnostic testing. Episode resources and references available at https://www.thermofisher.com/phadia/us/en/resources/immunocast/s1e13.html?cid=0ct_3pc_05032024_9SGOV4
More allergenic peanuts? Fungi in crops that may make patients more susceptible to food allergy sensitization? And what does the epithelial barrier hypothesis have to do with all of it? Tune into this newsroom episode of ImmunoCAST as we discuss a recently published review paper by Ashley Sang Eun Lee, MD, and Nicole Ramsey, MD, PhD, from the Icahn School of Medicine at Mount Sinai which presents some of the interesting ways that climate change may impact patients with food allergies. Episode resources and references available at https://www.thermofisher.com/phadia/us/en/resources/immunocast/s1e12.html?cid=0ct_3pc_05032024_9SGOV4
Ever since the CDC released its Morbidity and Mortality Weekly report about alpha-Gal syndrome (AGS) last summer, it seems that everyone is talking about this odd allergy to red meat. Whether you’re an allergist or a primary care clinician, get the clinical facts about AGS in this episode of ImmunoCAST where we explore the syndrome’s origins and discovery, what potential foods (some perhaps lesser known) and medical products may cause reactions, and the most effective way to diagnose and treat patients. Episode resources and references available at https://www.thermofisher.com/phadia/us/en/resources/immunocast/s1e11.html?cid=0ct_3pc_05032024_9SGOV4
Can patients tolerate baked forms of egg and milk? Is it a clinical peanut allergy or cross-reactivity with pollen? In this episode of ImmunoCAST, Gary and Luke dive into food allergen components and their impact on patient management. Their discussion covers specific proteins found in eggs, milk, peanuts, and tree nuts and what it means for patients who are sensitized to them. They also discuss the role of allergen component diagnostics, how it can provide clarity, and aid in appropriate patient care decisions. Episode resources and references available at https://www.thermofisher.com/phadia/us/en/resources/immunocast/s1e10.html?cid=0ct_3pc_05032024_9SGOV4
In this episode of ImmunoCAST, listen to a discussion around cannabis allergy and the importance of healthcare providers recognizing and inquiring about its exposure, especially in patients with asthma or food allergies. Gary and Luke delve into the history, routes of exposure, and the identification of specific allergens within cannabis, such as lipid transfer proteins, which may cross-react with other plant foods. This episode highlights the need for improved diagnostic methods and greater clinical awareness of cannabis as a potential allergen. Episode resources and references available at https://www.thermofisher.com/phadia/us/en/resources/immunocast/s1e9.html?cid=0ct_3pc_05032024_9SGOV4
In this episode of ImmunoCAST, Gary and Luke explore the new European Academy of Allergy and Clinical Immunology (EAACI) food allergy diagnosis guidelines. They break down some of the significant recommendations found within these guidelines, such as important questions clinicians should ask during a structured food allergy history, the role of diagnostic testing, and the use of testing with allergen components in a diagnosis. Episode resources and references available at https://www.thermofisher.com/phadia/us/en/resources/immunocast/s1e8.html?cid=0ct_3pc_05032024_9SGOV4
Is it really allergies causing patients’ rhinitis symptoms this spring or is it something nonallergic? Sure, pollen is out and about, but that doesn’t mean that those nonallergic triggers simply disappear when allergy season starts. Listen in as Gary and Luke discuss the different types of nonallergic rhinitis, potential triggers, and how healthcare providers can help provide clarity this allergy season when allergy medication isn’t working, and symptoms aren’t easing up. Episode resources and references available at https://www.thermofisher.com/phadia/us/en/resources/immunocast/s1e7.html?cid=0ct_3pc_05032024_9SGOV4
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