Chromatography Experts

Join host Abbie Breton and special guest Yuliya McAnany on Chromatography Experts as we explore AAV purification, cell & gene therapy advancements, and a new method from Tosoh that’s reshaping how researchers separate full and empty AAV capsids. We break down the science behind our recent paper, ‘Preparative choline-based anion-exchange chromatography for enrichment of full adeno-associated virus capsids’ and reveal the results, up to 90% full capsids with 75% recovery. You’ll also hear insights on scalability, method adaptation for other viral vectors, and expert advice for improving purification workflows. If you work with AAVs, this is an episode you don’t want to miss. The paper can be found here: https://www.sciencedirect.com/science/article/pii/S0021967325006636

Episode 6 of Chromatography Experts is out now! 🎙️ AAVs - From Basics to Breakthroughs What are AAVs, and why are they revolutionizing gene therapy? In this episode, we break down the science, highlight a breakthrough analytical method from Tosoh, and explore the future of AAVs in clinical development. 🔬 Whether you're in the lab or just curious about biotech innovation, this episode is packed with insights.

🔬 Episode #5 – Exploring Chromatography Resin Selection In this episode, we dive into selecting the right chromatography resins for bioprocessing applications and how important it is to have a trusted vendor in today’s market. 🎙️ Join our #ChromatographyExperts Phu Duong and Anson Lewis as they discuss Key factors influencing resin selection Performance comparisons across resin types Real-world case studies and lessons learned Upcoming innovations in resin technology 📌 Perfect for scientists, process engineers, and anyone curious about the science behind purification strategies. #Chromatography #Bioprocessing #ResinSelection #AAV #mAb #DownstreamProcessing #Podcast

🎧 Viral Clearance in Bioprocessing: Multi-Column Chromatography Edition In this episode of the Chromatography Experts Podcast, we take a closer look at viral clearance in Multi-Column Chromatography and why it matters. Marissa Heino and Abbie Breton joins us to explore: • What viral clearance means in bioprocessing • How MCC principles differ from batch • Highlights from our recent viral clearance study • Regulatory considerations, real-world implementation tips, and more 🎙️ Listen now to explore how MCC is shaping bioprocessing.   #ViralClearance #MCC #Bioprocessing #ChromatographyExperts #TosohBioscience #DownstreamProcessing #ContinuousChromatography #Pocast

Shedding light on MALS! In Episode 3 of our Chromatography Experts podcast, Phu Duong, Ph.D., sits down with special guest Tianyu Li, Ph.D., to unpack the power of Multi-Angle Light Scattering (MALS) — what’s new, how it’s used in chromatography, how easy it is to implement, and much more! #ChromatographyExperts #MALS #LightScattering #Podcast

Join our #ChromatographyExperts as they explore the science behind chromatography resins — from key terminology and applications to what sets different resins apart, and how they’re driving the next generation of purification in biomanufacturing.

Multi-Column Chromatography (MCC) is changing everything. But what exactly is MCC? How does it compare to traditional batch methods, and where is it taking bioprocessing next? Our #ChromatographyExperts break it all down in this episode.

Multi-Column Chromatography (MCC) is changing everything. But what exactly is MCC? How does it compare to traditional batch methods, and where is it taking bioprocessing next? Our #ChromatographyExperts break it all down in this episode.