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Autoimmune Alchemy

Author: Dr. Micah Yu and Dr. Melissa Mondala

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Join Dr. Micah Yu, a board-certified integrative rheumatologist, and Dr. Melissa Mondala, an integrative medicine and mental health expert, as they bridge the gap between cutting-edge science and soulful healing.

In Autoimmune Alchemy, this husband-and-wife MD team share personal stories, expert insights, and powerful patient journeys to explore how autoimmune illness and chronic disease can be transformed through integrative medicine.

From evidence-based science and integrative medicine to ancient healing wisdom and mindset practices, this podcast is your guide to whole-person health, from science to soul.
21 Episodes
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Dr. Ni-Cheng Liang, a board-certified integrative pulmonologist, shares her journey of being diagnosed with aggressive breast cancer at age 31 during pulmonary critical care fellowship.She combined clinical trials with acupuncture, traditional Chinese medicine, yoga, and Reiki to survive and thrive through five months of chemotherapy and three surgeries.We explore how mindfulness (6,000+ published studies) changes stress response at the genetic level, her work supporting burned-out healthcare professionals through the Mindful Healthcare Collective, and evidence-based treatments for long COVID including graded exercise for POTS and post-exertional malaise.Key TakeawaysIntegrative (evidence-based) ≠ alternative (unproven/dangerous)Mindfulness = present moment awareness without judgment6,000+ studies prove mindfulness works at genetic levelLong COVID is multi-systemic and underdiagnosedAnti-inflammatory diet: 5-9 servings vegetables/fruits dailyGraded exercise for long COVID: 5 min recumbent, increase 1-2 min weeklyAvoid upright exercise with POTS/post-exertional malaiseGroup movement in nature = community + exercise + healingChair yoga accessible for bedbound patientsMindfulness practice: anytime, anywhere, doing anythingChapters & Timestamps02:00 Integrative Modalities During Chemotherapy04:00 Evidence-Based vs. Alternative Therapies10:00 What Is Mindfulness? Science & Practice14:00 Mindfulness Changes Stress at Genetic Level18:00 Mindful Healthcare Collective & Burnout21:00 Long COVID: Multi-System Effects24:00 Anti-Inflammatory Diet & Movement26:00 Dragon Boat Racing: Community Healing30:00 Resources & Where to Find Dr. LiangGuest DetailsDr. Ni-Cheng Liang, MDBoard-Certified Integrative Pulmonologist, Cancer Survivor & Mindfulness TeacherCredentials:Pulmonary & Critical Care MedicineFellowship, University of Arizona Integrative MedicineFormer Executive Director, UCSD Center for MindfulnessCo-Host, Healing Medicine PodcastFounder, Mindful Healthcare Collective14+ year breast cancer survivorCo-Captain, Team Survivor San Diego dragon boat teamSpecializations: Long COVID, mindfulness-based stress reduction, asthma, COPD, cancer survivorship, healthcare burnout, graded exercise for
In this episode, I sit down with Maria Lloyd, a licensed marriage and family therapist specializing in trauma-informed therapy and ketamine-assisted psychotherapy, to explore how unresolved trauma lives in the body and manifests as autoimmune disease, particularly in highly sensitive people (HSPs) who make up 20% of the population.Maria shares her personal journey with her son's gut issues and mold exposure that led to complete dysfunction until they addressed both the physical detoxification and mental health trauma through ketamine-assisted psychotherapy, ultimately leading to his full healing and return to college.We discuss how narcissistic relationships create constant fight-or-flight stress that directly impacts the nervous system and gut health, why turning toward pain with compassion (rather than running from it) calms both emotional and physical symptoms, and how creating secure attachments through therapy can rewire dysregulated nervous systems formed in childhood.Key Takeaways20% of people are highly sensitive (HSPs) - understanding this trait reduces shame and helps create supportive lifestylesTrauma lives in the body; turning toward pain with compassion calms both emotional and physical symptomsMold exposure can be like "pouring gasoline on the fire" for those with gut issues and mental health challengesKetamine-assisted psychotherapy works at a somatic level, helping people reconnect with their bodies and feel safeEarly childhood attachment patterns affect nervous system regulation and autoimmune disease riskNarcissistic relationships cause constant fight-or-flight stress that directly impacts gut health and autoimmunityHealth dramatically improves when people leave narcissistic relationships or set firm boundariesMorning and evening routines (walking, yoga, Qigong, Tai Chi, breath work) create nervous system stabilityResearch shows Qigong and yoga reduce pain and flares in lupus, rheumatoid arthritis, and fibromyalgiaIt's through relationships that we heal - secure attachments with therapists can rewire dysregulated nervous systemsChapters & Timestamps00:00 Welcome: Maria Lloyd & Trauma-Informed Therapy02:00 Maria's Personal Journey: Her Son's Gut Issues & Mold Exposure03:00 When the Medical System Failed: The Natural Health Journey03:30 Mold Detoxification, Diet Changes & Ketamine-Assisted Psychotherapy04:00 The Holistic Approach: Everything Is Connected04:30 Navigating Pain Cycles & Hypervigilance in Autoimmune Flares05:00 Trauma Lives in the Body: Turning Toward Pain with Compassion06:00 Creating Secure Attachment with Ourselves07:00 Attachment Styles & Their Impact on Nervous System Regulation08:00 How Early Childhood Attachment Affects the Brain & Body09:00 Two Autoimmune Phenotypes: Type A Perfectionists & Highly Sensitive People10:00...
In this episode, I sit down with Dr. Trisha Pasricha, a Harvard-trained gastroenterologist who directs the Gut-Brain Research Lab at Beth Israel, to reveal why IBS isn't "all in your head" and how specialized antibody testing can uncover autoimmune attacks on gut neurons. We explore the IBS-fibromyalgia overlap, why one in three people develop IBS after infections, and her groundbreaking research showing smartphone scrolling in bathrooms increases hemorrhoid risk by 46%.Dr. Pasricha shares evidence-based treatments including peppermint oil and psyllium fiber while debunking probiotic myths, and explains why constipation may be an early Parkinson's warning sign. This conversation validates patients dismissed by doctors and proves these conditions have real pathology requiring collaborative care across specialties.Key TakeawaysIBS is NOT "all in your head"—pathology lives in the deep enteric nervous system where standard tests can't reach90% of gut-brain communication flows UPWARD through the vagus nerve, not downward from stressOne in three people who get gastroenteritis will develop IBS from "scarring" of gut neuronsThe Mayo Paraneoplastic Panel can detect autoimmune antibodies attacking gut neurons (specialized test)Many IBS patients also have fibromyalgia—treatments often overlap (SNRIs, peppermint oil, fiber)Psyllium fiber (25g women, 38g men daily) works for BOTH constipation and diarrhea—it's a "shapeshifter"Probiotics are NOT recommended by gastroenterology guidelines—feed your microbiome with fiber and fermented foods insteadSmartphone scrolling in the bathroom increases hemorrhoid risk by 46%—limit to 5 minutes maximumConstipation may be an early Parkinson's warning sign—the disease likely begins in the gutH. pylori is abnormally prevalent in Parkinson's patients and treating it can improve tremors by enhancing levodopa absorptionChapters & Timestamps00:00 Introduction to Dr. Trisha Pasricha & Gut-Brain Research02:00 What Is IBS & Why It's Not "All in Your Head"04:00 The Enteric Nervous System: Our "Second Brain"07:00 The Autoimmune Connection to IBS10:00 IBS-Fibromyalgia Overlap & Treatment Crossover13:00 Mayo Paraneoplastic Panel: Testing for Autoimmune IBS16:00 Getting Second Opinions & Finding Neuro-GI Specialists19:00 Social Media Education: Benefits & Rabbit Holes21:00 Evidence-Based Treatments: Peppermint Oil & Psyllium Fiber26:00 The Truth About Probiotics: Not Recommended29:00 Fiber Diversity & the Mediterranean Diet Connection33:00 Groundbreaking Research: Smartphones & Hemorrhoids (46% Risk)36:00 Parkinson's Disease Begins in the Gut38:00 The GI-Neuro Parkinson's Clinic Model42:00 H. Pylori Connection to Parkinson's & Rheumatic...
In this episode, Dr. Melissa Mondala sits down with Dr. Felice Gersh, an integrative OB-GYN, to explore why 80% of all autoimmune patients are women and how our two X chromosomes create a more robust immune system that can become overactive when hormones become imbalanced.Dr. Gersh explains the fascinating connection between leaky gut, hormonal dysfunction (PCOS, amenorrhea, menopause), and autoimmune diseases like Hashimoto's and rheumatoid arthritis, revealing how molecular mimicry causes antibodies against gut bacteria to cross-react with our own tissues.They discuss why rheumatologists often miss the root cause by only prescribing biologics that block immune responses without addressing leaky gut and hormone imbalances, and how early intervention with nutrition, stress management, sleep, and hormone balancing can reverse positive ANA antibodies and prevent full-blown autoimmune diseaseKey Takeaways80% of all autoimmune patients are female due to two X chromosomes with immune-related genes15% of genes on the "turned off" X chromosome stay active forever—almost all are immune-relatedWomen make more antibodies, have higher white blood cell counts, and mount stronger immune responsesEvery woman with hormonal dysfunction (PCOS, amenorrhea, menopause) develops gut dysbiosisLeaky gut allows bacteria and toxins to escape, triggering antibody production through molecular mimicryRheumatoid arthritis is linked to specific gut bacteria leaking through the intestinal barrierBiologics (Humira, Remicade) only block symptoms; they don't fix leaky gut or hormone imbalancesPositive ANA = pre-autoimmunity = leaky gut—early intervention can reverse itVegan diet high in fiber and polyphenols can reduce rheumatoid arthritis pain by 50% in one monthHormone balancing, gut repair, stress management, and nutrition work synergistically—it's all of the aboveChapters & Timestamps01:00 Introduction: Dr. Felice Gersh on Women & Autoimmune Disease01:30 Why Women Have More Robust Immune Systems02:00 The Two X Chromosomes & Immune-Related Genes02:30 15% of X Chromosome Genes Stay Active Forever03:00 Women Make More Antibodies & Have Higher White Blood Counts04:00 Estradiol & Progesterone's Role in Immune Function04:30 Leaky Gut, Endotoxins & Gut-Associated Lymphoid Tissue05:00 PCOS, Amenorrhea & Menopause Always Cause Gut Dysbiosis06:00 Molecular Mimicry: How Antibodies Attack Your Own Organs06:30 Hashimoto's: The Most Common Autoimmune Disease in Women07:00 Rheumatoid Arthritis Linked to Specific Gut Bacteria08:00 Every Woman with Autoimmune Disease Has Leaky Gut08:30 Biologics Block Symptoms, Not Root Causes09:00 The Integrative Approach: Hormones, Gut & Low Dose Naltrexone09:30 High Cortisol from Stress Causes Leaky Gut10:00 Fiber, Polyphenols & Nurturing Your Gut Microbiome10:30 Why Biologics Stop Working After 2-4 Years11:00 Pre-Autoimmunity: Positive ANA Without Disease Yet11:30 Reversing...
In this episode, I sat down with John Banta, a retired certified industrial hygienist with over 35 years of experience, who discovered mold was destroying his wife's health after she recovered completely during a camping trip, leading him to dedicate his career to becoming a "mold doctor" for buildings.John reveals how 1 in 5 brand new homes has mold before occupation, why killing mold actually makes it produce more biotoxins as a defense mechanism, and his revolutionary microfiber and soapy water technique that actually removes mold instead of spreading it.We discuss the connection between mold exposure and autoimmune conditions like fibromyalgia and chronic fatigue, how COVID-19 can trigger mold sensitivity in 24% of the population with HLA-positive genetics, and his groundbreaking pathways testing method to find hidden mold using peptide bonds.Key TakeawaysIf you smell mold, it's actively growing - mold only produces musty odors when wet1 in 5 brand new homes has mold before occupation due to construction practicesYou can't see mold until there are 1-10 million colony-forming units per square inchNever kill mold - it fights back by producing more biotoxins as a defense mechanismSoapy water (5 drops detergent in a quart) + microfiber cloths remove mold effectivelyVinegar doesn't work because "oil and vinegar don't mix" - you need detergent to emulsify lipids24% of people have HLA-positive genetics; COVID-19 can trigger mold sensitivity overnightConcrete slabs take almost a year to lose 90% of moisture - premature building causes moldDead mold still makes you sick - removal is essential, not just killing itAn ounce of prevention: catching mold early can save $45,000+ in remediation costsChapters & Timestamps00:00 Opening Teaser & Introduction to John Banta02:00 Where Mold Is Found: Beneficial Uses & Hidden Dangers03:00 John's Personal Journey: His Wife's Mystery Illness04:00 The Camping Trip That Changed Everything05:00 It's Always About the Water07:00 Mold Syndrome: Why Symptoms Vary So Much10:00 Medical Schools Don't Teach About Mold & Autoimmunity12:00 The Lead Poisoning Story & Daughter's Miracle17:00 How to Determine If Your Home Has Mold19:00 Clean Room Technology & Microfiber Innovation23:00 Why Vinegar Doesn't Work & Soapy Water Does25:00 Never Kill Mold: It Fights Back with Biotoxins27:00 Hidden Wall Damage: The 32-Foot Leak Case29:00 1 in 5 New Homes Have Mold Before Occupation31:00 Concrete Slabs & the Year-Long Drying Problem34:00 COVID-19 Triggers Mold Sensitivity in 24% of People37:00 The Seared Steak Problem: Why Dehumidifiers Aren't Enough40:00 Finding the Right Remediation...
In this episode, Dr. Melissa Mondala sits down with Dr. Sam Ko, board-certified emergency medicine physician and medical director at Reset Ketamine, to explore how ketamine therapy is helping the 50-70% of autoimmune patients struggling with depression, anxiety, and chronic pain.They discuss how ketamine resets hypersensitized pain receptors, reduces inflammatory markers like TNF-alpha and IL-6, influences the gut-brain connection, and provides real hope for conditions like fibromyalgia, rheumatoid arthritis, MCAS, and POTS.Dr. Ko shares success stories, introduces Stellate Ganglion Block (SGB) as a complementary treatment, and reminds us that your struggle is real and there are evidence-based tools to help you reclaim functional living.Key Takeaways50-70% of autoimmune patients experience depression, anxiety, and central sensitization - there's a fascinating connection between autoimmune conditions and mood disordersKetamine resets hypersensitized pain receptors via NMDA receptors down the spinal cord, making it powerful for central sensitizationThe central nervous system and enteric nervous system share the same embryological origin (neuro crest), explaining the profound gut-brain connectionKetamine influences the gut microbiome, which in turn affects the central nervous system and moodExtended infusion protocols (80 minutes to 4 hours) are used for chronic pain conditions like fibromyalgiaKetamine reduces inflammatory markers including TNF-alpha, IL-6, and IL-10, helping to "turn down the volume" on overactive immune systemsStellate Ganglion Block (SGB) provides a "hardware reset" for the sympathetic nervous system, complementing ketamine's "software reset"Success is measured in functional improvements - getting out of bed, doing hobbies, walking 5 minutes daily - not running marathonsTeam-based care is essential, especially for patients on biologics and immunosuppressants - collaboration with rheumatologists and primary care is keyYour struggle is real, your body is wise - if a provider doesn't listen, find one who willChapters & Timestamps00:00 Introduction: Ketamine for Autoimmune Depression, Anxiety & Pain00:30 The Autoimmune-Mental Health Link: Why 50-70% Experience Both01:00 Central Sensitization: Resetting Hypersensitized Pain Receptors via NMDA02:30 Ketamine Beyond the ER: Treating MCAS, POTS & Complex Autoimmune Conditions03:00 The Gut-Brain Connection: Embryology of Central & Enteric Nervous Systems04:00 Serotonin in Gut & Brain: Why "Trust Your Gut" Is Literally True04:30 How Ketamine Influences the Gut Microbiome & Central Nervous System06:00 Success Stories: Fibromyalgia & Extended Infusion Protocols07:00 Rheumatoid Arthritis: Visible Reduction in Joint Inflammation07:30 Reducing Inflammatory Markers: TNF-alpha, IL-6, IL-1008:30 Mind-Body Connection: Breaking the...
In Part 2 of this Autoimmune Alchemy conversation, Dr. Micah Yu is joined again by Dr. Robin Rose — family medicine physician, peptide specialist, and kidney health educator — to move from awareness into actionable healing strategies.This episode dives deep into peptides, bio-regulator therapies, and lifestyle foundations that support kidney repair in autoimmune disease. Dr. Rose explains how autoimmune inflammation damages kidney tubules, blood vessels, and mitochondria, and how targeted tools can help reverse epigenetic injury rather than simply slow decline.TimeStamps[0:00] — Part 2 Kickoff: Strategies, Peptides & Bio-Regulators[1:00] — “Renal Vulnerability Syndrome”: Autoimmune Impact on Kidneys (Quick Review)[3:00] — Anti-Inflammatory Diet for Kidney Protection: Polyphenols, Herbs, Teas, Toxins[9:00] — Protein, Carnivore Diets & Why Kidney Nutrition Must Be Personalized[12:00] — Sugar, Glycotoxins, Gluten/Grains & Practical Kidney-Friendly Protein Choices[19:00] — Peptides vs Bio-Regulators: What They Are + Epigenetics Explained[28:00] — Core Support Stack: Nutrients, Sleep/Circadian (Pineal), Carnosine + Clean Labels[35:00] — Best Peptides/Bio-Regulators for CKD & Autoimmunity + Sequencing + Wrap/Resources[45:00] — Where to Find Dr. Rose + ClosingKey TakeawaysUnderstand how autoimmune inflammation creates “renal vulnerability syndrome,” quietly damaging kidney tubules and mitochondria.Discover why kidney decline is largely an epigenetic injury — and how that means it can be modulated and improved.Learn the difference between peptides and bio-regulators, and why bio-regulators can directly influence gene expression.Explore anti-inflammatory nutrition strategies that protect kidneys, including polyphenols, herbs, teas, and cooking methods.In Part 2, Dr. Robin Rose reframes kidney disease not as a fixed diagnosis, but as a dynamic, modifiable process shaped by immune signaling, epigenetics, lifestyle, and targeted therapies. By combining peptides, bio-regulators, nutrition, and mindset, she offers a compassionate and science-based approach to healing that empowers patients rather than frightening them. This episode reminds us that recovery is not about perfection — it’s about informed, consistent choices that restore balance over time.
In this episode of Autoimmune Alchemy, Dr. Micah Yu sits down with Dr. Robin Rose — family medicine physician, peptide specialist, and kidney health educator — to uncover a critical but often overlooked topic: early kidney decline in autoimmune disease.Dr. Rose shares her powerful personal story of surviving kidney cancer, losing a kidney, and reversing what doctors told her was irreversible kidney failure. She explains why kidney damage often begins long before standard labs change, how autoimmune inflammation quietly stresses kidney tubules, blood vessels, and mitochondria, and why many patients are told to “wait” instead of act.This conversation reframes kidney health as something proactive, reversible, and deeply connected to autoimmune disease, gut health, lifestyle, peptides, and mindset — offering hope and actionable insight for patients at every stage.TimeStamps[0:00] — Introduction: Autoimmune Disease & the Forgotten Role of the Kidneys[1:20] — Dr. Robin Rose’s Story[7:40] — Why Kidney Damage Starts Before Labs Change[11:35] — How Autoimmune Disease Stresses Kidney Tubules, Blood Vessels & Mitochondria[17:17] — Diet, Protein, Acidity & Lifestyle Choices That Impact Kidney Health[25:20] — The Gut–Kidney–Immune Axis: Dysbiosis, Uremic Toxins & Inflammation[31:00] — Early Detection Tools, Binders & Proactive Kidney Protection[50:00] — Hope, Mindset & Setting the Stage for Part 2 (Peptides & Therapies)Key TakeawaysDiscover why autoimmune disease creates kidney vulnerability long before creatinine or GFR appear abnormal. Understand how inflammation, immune complexes, and vascular damage quietly stress kidney tubules and blood vessels. Learn why early kidney decline is often missed — and why waiting for “bad labs” delays prevention. Uncover the difference between kidney filtration (glomeruli) and reabsorption (tubules), and why tubules are damaged first. Explore how autoimmune conditions like lupus, Sjögren’s, RA, MS, and Hashimoto’s increase renal risk through inflammation and dysbiosis. Dr. Robin Rose’s story challenges the belief that kidney decline is inevitable. By understanding early warning signs, supporting the gut–immune–kidney axis, and shifting from fear to informed action, patients with autoimmune disease can protect their kidneys long before crisis occurs. Part 1 offers clarity, empowerment, and hope — reminding us that prevention begins with awareness and belief in healing.
In this episode of Autoimmune Alchemy, Dr. Melissa Mondala welcomes Dr. Peter Kan — board-certified chiropractor, functional neurologist, and functional medicine expert known for bridging the gut–brain–immune connection. Dr. Kan works extensively with Hashimoto’s, rheumatoid arthritis, lupus, Sjögren’s, mixed connective tissue disease, MS, and patients with “autoimmune of unknown origin.” In this conversation, he breaks down why autoimmune patients so often struggle with food sensitivities, inflammatory flares, neurological symptoms, and overlapping autoimmune conditions thattraditional medicine misses. He explains the difference between allergies, sensitivities, and intolerances, why “food can be medicine or poison,” and how immune pathways like T-reg cells, Th17 activation, NF-kB, and leaky gut shape the autoimmune experience. He also shares strategic supplements, lifestyle foundations, and a practical roadmap for people who are overwhelmed, undiagnosed, or stuck in flare cycles.TimeStamps[0:00] — Understanding the Gut–Brain–Immune Connection[1:40] — How Food Sensitivities Trigger Autoimmune Flares[3:27] — Why Autoimmune Symptoms Spread Throughout the Body[5:44] — Allergies vs. Sensitivities vs. Intolerances Explained[8:34] — Foundational Supplements for Reducing Inflammation[10:54] — T-Reg Cells, Glutathione & Immune Modulation[14:17] — Elimination Diets, Testing & Reintroductions[16:57] — Personalizing Your Autoimmune Nutrition PlanKey TakeawaysDiscover how food sensitivities ignite autoimmune flares by ramping up the immune system and triggering tissue inflammation. Understand why many patients have “autoimmune of unknown origin” long before receiving an official diagnosis. Explore the difference between allergies (IgE), sensitivities (IgG/IgA), and intolerances (enzyme-based) — and why each requires a different treatment approach. Learn how food reactions can show up as fatigue, brain fog, sinus issues, weight changes, joint pain, skin symptoms, or mood shifts — not just digestive problems. Uncover how regulatory T-cells work as the “brake pedal” of the immune system, and why supporting them helps quiet autoimmune activity and move toward remission. Dr. Peter Kan brings clarity to one of the most confusing and overwhelming parts of autoimmune disease: the relationship between food, inflammation, and immune dysregulation. His science-backed but practical approach helps patients understand why they react to so many foods, how to begin healing gut and immune pathways, and how to move toward remission through immune modulation — not fear or restriction. This conversation offers hope, direction, and a clear roadmap for anyone lost in the world of autoimmune flares.
Welcome to another episode of Autoimmune Alchemy, Dr. Micah Yu sits down with Dr. Kara Wada — board-certified allergist, immunologist, lifestyle medicine physician, Sjögren’s patient, and founder of The Immune Confidence Institute. Dr. Wada opens up about her long diagnostic journey with Sjögren’s, why so many patients are dismissed or misdiagnosed, and how clinical “gray zone” diseases like seronegative Sjögren’s, MCAS, dysautonomia, and chronic fatigue often fall through the cracks in modern medicine. She also shares the lifestyle changes, supplements, and clinical trial therapy (dazodalibep) that changed her health, plus the innovative lymph-node–targeted allergy treatment she now offers in her clinic.Time Stamps[0:00] — Welcome & Introduction[1:07] — Early Symptoms & Missed Red Flags[3:45] — Diagnosis Journey & Lab Findings[6:12] — What Sjögren’s Really Is[7:50] — Dryness Isn’t Always the First Symptom[9:26] — Misrouted Specialists & Delayed Diagnosis[9:50] — Full Symptom Breakdown[14:16] — Lifestyle Changes That Helped[15:30] — New Sjögren’s Drug Trial (Dazodalibep)[18:10] — Future Treatments & Seronegative Gap[19:39] — Supplements That Helped[23:14] — “Clinical Ghosts” & Why Patients Are Dismissed[27:17] — Rethinking Mast Cells & MCAS[29:06] — ISLIT Protocol (Lymph-Node Immunotherapy)[30:30] — Closing & Part 2 TeaserKey TakeawaysDiscover why Sjögren’s isn’t rare — only rarely diagnosed — and how normal labs can still hide the disease.Understand why dryness doesn’t always appear first and how neurological issues, fatigue, migraines, and POTS often come earlier.Learn how over-reliance on blood work leads doctors to dismiss patients whose symptoms don’t fit textbook patterns.Uncover the deep neurological involvement in Sjögren’s, including dizziness, orthostatic intolerance, and chronic headaches.Explore the lifestyle tools that helped Dr. Wada improve, including sleep optimization, stress management, and plant-forward nutrition.Autoimmune patients can be overlooked — even when the symptoms are loud and life-altering. Dr. Kara's perspective as both a...
In this episode of Autoimmune Alchemy, host Dr. Micah Yu speaks with Dr. Kelly McCann, an expert in internal medicine, functional medicine, and environmental medicine, about chronic illnesses and their root causes. Dr. McCann discusses the concept of total toxic load and how various factors such as mold exposure, chronic infections like Lyme disease, and environmental toxins contribute to complex chronic conditions. She explains the various symptoms and diagnostic challenges of these illnesses, particularly emphasizing the importance of early identification and personalized treatment. Dr. McCann also emphasizes the role of mind-body-spirit connection in the healing process and how trauma and emotional well-being can impact physical health. Additionally, the discussion covers hypermobility, Ehlers-Danlos syndrome (EDS), and Mast Cell Activation Syndrome (MCAS), providing insights into their management and treatment. This episode serves as a valuable resource for those seeking a deeper understanding of chronic illnesses and how to navigate their complexity.Here are some time stamps to support you. 00:00 Introduction and Guest Welcome01:25 Understanding Chronic Illnesses and Root Causes02:08 The Concept of Total Load and Environmental Medicine03:27 Mold and Mycotoxins: A Major Player04:15 Chronic Infections and Their Impact06:19 Environmental Toxins and Genetic Susceptibilities07:36 Diagnosing and Treating Mold Toxicity21:07 Mind-Body-Spirit Connection in Healing23:27 Exploring Trauma and Emotional Healing32:11 Energy Medicine and Self-Discovery38:02 Lyme Disease and Co-Infections39:48 A Family's Lyme Disease Journey40:13 Understanding Lyme Disease Transmission41:08 Divergent Views on Lyme Disease44:08 Chronic Lyme and Functional Medicine47:06 The Importance of Asking 'Why' in Medicine54:03 Hypermobility and Ehlers-Danlos Syndrome01:07:29 Mast Cell Activation Syndrome Explained01:15:48 Concluding Thoughts and ResourcesUncover the truth behind chronic illnesses with Dr. Micah Yu and Dr. Kelly McCann. From Lyme disease to Mast Cell Activation Syndrome, this episode explores the root causes and innovative treatments for complex conditions. Don't miss this insightful conversation on Autoimmune Alchemy! #IntegrativeMedicine #PodcastLife
Women often first meet autoimmunity during hormonal transitions like perimenopause and menopause. In this conversation, in this episode, Dr. Melissa Mondala and Dr. Jennifer Roelands (OB-GYN, integrative and functional medicine) unpack how shifting estrogen and progesterone interact with the immune system, why the gut–brain–hormone axis matters for mood and symptoms, and what to do first if you are seeing new labs, new aches, or a metabolism that no longer plays by your old rules. You will hear practical ways to lower inflammation, protect bone and muscle, choose labs that actually guide care, and build “low-hanging fruit” habits that stick.Key takeawaysHormone transitions can “flip on” latent genes and unmask autoimmunity; gut health and hormone metabolism are tightly linked.Do not skip the gut: the estrobolome, serotonin production, barrier integrity, and antibodies formed in the gut influence thyroid and joint autoimmunity.Start small to beat overwhelm: stack easy “wins” such as step-ups, resistance bands, or brief “exercise snacks” while you build consistency.Protect bone and muscle: lift 2–3x weekly, add protein and fiber, and consider DEXA earlier than 65 to get a baseline.Labs that help: iron panel, vitamin D, CRP, fasting insulin, thyroid panel, and cycle-timed sex hormones; wearables or CGM can add useful data.Options exist: HRT is one path; omega-3s, fiber, magnesium (glycinate), curcumin, and targeted botanicals can also support symptoms and sleep.Perimenopause is more than hot flashes: watch for unusual signs like ear itching, body-odor changes, recurrent UTIs, libido shifts, or oral-health changes.Suggested chapters 00:00 Intro and guest background 00:26 Why autoimmunity often appears in perimenopause 00:29 Gut–hormone metabolism, estrobolome, neurotransmitters 00:31 Stress load and “low-hanging fruit” habit building 00:34 Muscle and bone loss, strength training that fits pain levels 00:36 HRT, DEXA baselines, and fracture risk context 00:39 Supplement staples: omega-3s, fiber, magnesium, curcumin 00:42 Weight and metabolism changes, personalized nutrition 00:44 Unusual symptoms of perimenopause 00:46 Early or premature menopause and risk profile 00:49 Finding the right clinician; advocating for labs 00:51 What to test and how to time hormones 00:53 Where to find Dr. Roelands and her practicePerimenopause is a whole-system transition. Pair smart medical care with gut support, resistance training, sleep, stress tools, and cycle-aware labs. Start with one easy win, get a baseline DEXA earlier, and build from there. The goal is not perfection. It is steady, sustainable progress that protects your brain, bones, and immune system.Host Bio:Dr. Melissa Mondala is a triple specialist in family medicine, lifestyle medicine, and integrative/primary care psychiatry. She is double board certified in family medicine and lifestyle medicine, completed her family medicine residency and Lifestyle Medicine Fellowship at Loma Linda University Health, and earned her MD from Chicago Medical School along with master’s degrees in Health Administration and Biomedical Science. Dr. Mondala is co-founder of Dr. Lifestyle in Newport Beach, where she provides direct primary care, integrative mental health, and lifestyle-based prevention for patients locally and via telehealth. She has served as core faculty in Preventive/Lifestyle Medicine at Loma Linda University and has contributed to national education in lifestyle medicine. She also co-hosts the Autoimmune Alchemy podcast with Dr. Micah Yu and leads the Integrative Mental Health Summit, bringing root-cause...
In this episode, Dr. Micah Yu welcomes Dr. Nisha Manek, integrative rheumatologist and author of Bridging Science and Spirit, for a wide-ranging conversation on where medicine is headed and why energy, the biofield, and conscious self-care belong beside conventional treatment. Hear how immune dysregulation shows up across the body, why drugs alone rarely create remission, and how subtle-energy practices, fascia and meridian science, sleep, intention, and community can help people with autoimmune disease feel better and do more. Key takeawaysWhat “biofield” means in plain language, how it relates to meridians, fascia, and whole-body connectivity, and why energy is a missing “vital sign” in clinicWhy rising autoimmune rates suggest we need more than medications alone, and how subtle-energy work can complement standard care to move patients toward remissionPractical self-regulation: simple hand “circuit” placements to recharge, gentle movement such as tai chi or qigong, sleep, nutrition basics, and intention settingA clinician’s perspective on research limits for energy medicine and how physics concepts help translate ancient ideas into modern practicePatient empowerment: build your plan with your doctor, add safe energy practices, and lean on community to reduce overload and stick with healing habitsSuggested chapters[00:00] Intro and guest background[02:00] From conventional training to integrative practice[05:00] Autoimmunity on the rise and environmental triggers[08:00] Beyond drugs: energy as the “missing mechanism”[11:00] The biofield as a vital sign[13:00] Meridians, chi, chakras, and a physics “umbrella”[15:00] Fascia as the body’s connective highway[20:00] A simple at-home hand circuit to recharge[29:30] The qigong headache story and what it implies[36:00] Medicine catching up, clinician burnout, patient agency[39:00] Where to find Dr. Manek and programsAutoimmune care improves when we pair smart conventional treatment with practices that restore the body’s energy and calm the nervous system. Start where you are: sleep, nutrition, gentle movement, and a simple daily recharge practice. Use your medical team for diagnostics and safety, then add community for support and momentum. The goal is not perfection. It is steady, sustainable progress toward remission and a fuller life.Guest resourcesDr. Manek’s Website: https://www.nishamanekmd.com/Get Dr. Manek’s Book: Bridging Science and Spirit: https://www.nishamanekmd.com/book Host Bio:Dr. Micah Yu is a board-certified integrative rheumatologist who blends conventional care with lifestyle and nutrition to help people reverse inflammation and live well with autoimmune disease. He is board certified in rheumatology, internal medicine, and lifestyle medicine, completed his residency and rheumatology fellowship at Loma Linda University, and earned his MD from Chicago Medical School along with master’s degrees in biomedical sciences and health care administration. He also completed fellowship training in integrative medicine at the University of Arizona. Dr. Yu co-founded Dr. Lifestyle in Newport Beach, California, where he sees patients locally and via telemedicine. He also co-hosts the Autoimmune Alchemy podcast with Dr. Melissa Mondala, bringing evidence, empathy, and practical tools to a global audience. His clinical perspective is informed by his own journey with autoimmune disease and by the results he has seen when patients pair targeted...
When Infections Inflame the Mind: Lyme, MS, and the Gut–Brain ConnectionDr. Darin Ingels connects the dots between chronic infections (like Lyme), the gut–brain axis, and neuroinflammation—explaining “leaky gut/leaky brain,” vagus-nerve signaling, mast-cell activation, and why mood, brain fog, and sleep often shift with immune activity. He shares practical supports—from joy practices to potent, targeted herbs—and how to vet supplement quality for safety and results. Key takeaways:Leaky gut and “leaky brain” often travel together; restoring gut function improves brain function. The vagus nerve can transmit gut signals that open the blood–brain barrier and drive neuro-inflammation. In Lyme and MS, immune cross-reactivity and mast-cell activation can inflame brain and nerves, contributing to anxiety, depression, OCD, and brain fog. Joy and regulation tools matter: music, humor, nature, and realistic activity resets help shift mental state on hard days. Herbal medicine is multi-targeted: combinations can modulate inflammation, immunity, hormones, and circulation—often at low doses with strong effects. Adaptogens to balance stress/cortisol: eleuthero (Siberian ginseng), rhodiola, holy basil, Ashwagandha—choose by symptom pattern (e.g., “tired-and-wired”). Sleep supports: lemon balm, chamomile, passionflower, kava, California poppy; nutrients like magnesium and 5-HTP/L-tryptophan help with staying asleep. Pain/inflammation options: highly bioavailable curcumin, Boswellia (frankincense), white willow bark, and devil’s claw (Harpagophytum). Quality matters: look for GMP certification and third-party testing; request Certificates of Analysis; be cautious with heat-exposed or counterfeit online products. Forms and safety: tinctures, capsules, teas, glycerites—many herbs are GRAS with low toxicity when sourced and dosed correctly. Conclusion: Integrative mental health isn’t brain-only; it’s gut, immune, nerves, and daily rhythms working together. With clearer roots (infection, mast cells, barrier integrity) and practical tools (tailored herbs, joyful resets, vetted supplements), you can calm neuro-inflammation and support steadier mood, sleep, and cognition, step by step. Host Bio:Dr. Melissa Mondala is a triple specialist in family medicine, lifestyle medicine, and integrative/primary care psychiatry. She is double board certified in family medicine and lifestyle medicine, completed her family medicine residency and Lifestyle Medicine Fellowship at Loma Linda University Health, and earned her MD from Chicago Medical School along with master’s degrees in Health Administration and Biomedical Science. Dr. Mondala is co-founder of Dr. Lifestyle in Newport Beach, where she provides direct primary care, integrative mental health, and lifestyle-based prevention for patients locally and via telehealth. She has served as core faculty in Preventive/Lifestyle Medicine at Loma Linda University and has contributed to national education in lifestyle medicine. She also co-hosts the Autoimmune Alchemy podcast with Dr. Micah Yu and leads the Integrative Mental Health Summit, bringing root-cause strategies for anxiety, mood, and brain health to a wider audience. Her approach blends diagnostics and conventional care with nutrition, sleep, movement, stress tools, and community to help patients reduce inflammation and build long-term resilience.
SummaryIn this in-depth interview, Dr. Micah Yu speaks with Dr. Ty Vincent, founder of Low Dose Immunotherapy (LDI), about his groundbreaking work in retraining the immune system. Dr. Vincent shares his journey from conventional medicine to developing LDI, explains how it differs from traditional allergy therapies and homeopathy, and reveals the remarkable outcomes he’s seen in patients with autoimmune and chronic illnesses. Together, they explore real-world success stories, the science of molecular mimicry, and why focusing on mechanisms rather than diagnoses may be the future of medicine.Key TakeawaysDiscover how Dr. Vincent’s path from family medicine to integrative care led him to create LDI.Learn the difference between Low Dose Allergen Immunotherapy (LDA) and Low Dose Immunotherapy (LDI).Explore how LDI addresses immune tolerance rather than suppression, and why it works for conditions beyond allergies.Hear case studies of patients with rheumatoid arthritis, Crohn’s disease, celiac disease, Lyme disease, Hashimoto’s, psoriasis, and more who experienced remission or dramatic improvements.Understand the concept of molecular mimicry and its role in autoimmunity.See how LDI provides a safer, low-risk alternative to lifelong immunosuppressive drugs.Gain insight into Dr. Vincent’s ongoing innovations, including potential breakthroughs for type 1 diabetes.This conversation highlights a profound shift in how we can view and treat chronic illness. Instead of suppressing the immune system, Dr. Vincent’s work with LDI shows what’s possible when we restore tolerance and reprogram the body’s natural defenses. It’s an eye-opening discussion that offers hope for anyone struggling with autoimmunity or unexplained chronic conditions.Host Bio:Dr. Micah Yu is a board-certified integrative rheumatologist who blends conventional care with lifestyle and nutrition to help people reverse inflammation and live well with autoimmune disease. He is board certified in rheumatology, internal medicine, and lifestyle medicine, completed his residency and rheumatology fellowship at Loma Linda University, and earned his MD from Chicago Medical School along with master’s degrees in biomedical sciences and health care administration. He also completed fellowship training in integrative medicine at the University of Arizona. Dr. Yu co-founded Dr. Lifestyle in Newport Beach, California, where he sees patients locally and via telemedicine. He also co-hosts the Autoimmune Alchemy podcast with Dr. Melissa Mondala, bringing evidence, empathy, and practical tools to a global audience. His clinical perspective is informed by his own journey with autoimmune disease and by the results he has seen when patients pair targeted therapies with nutrition, sleep, movement, and stress resilience. Website: https://myautoimmunemd.com/
CIRS, Mold, and Autoimmunity: Getting Off the Inflammation Roller CoasterThis is an encouraging and educational interview for anyone navigating Chronic Inflammatory Response Syndrome (CIRS) Dr. Melissa Mondala sits down with Jenny Johnson, a CIRS guide and community-builder, to unpack how biotoxin exposure from water-damaged buildings, mold, bacteria, and Lyme can drive chronic inflammation that mimics or even triggers autoimmune disease. They cover what to look for, how to differentiate CIRS from conditions like lupus, MS, and RA, and why environmental cleanup, sleep, nervous system support, and community are foundational. Jenny also shares moving recovery stories and practical ways families can pace healing without burning out. CIRS is a chronic inflammatory response to biotoxins the body cannot easily clear. Symptoms can mirror lupus, MS, and RA, and CIRS may coexist with or trigger autoimmune flares. Taking a careful timeline, targeted labs, and sometimes imaging helps sort out what to treat first. Key takeawaysLearn what CIRS is and how it overlaps with autoimmunity.Discover why “remove the exposure” is step #1.Cleaning up or leaving a water-damaged environment reduces daily biotoxin load. Explore "pairing" detox strategies so the immune system can calm and autoimmune symptoms become more manageable. Learn the “brain on fire and brain on ice” model.Discover the early anchors of recovery.Learn why community speeds healing.Discover hope through real-world stories.CIRS can cause anxiety, depression, panic, rage, and cognitive issues like brain fog and executive dysfunction. Having a coach or community to be your “borrowed brain” reduces overwhelm while you recover. Prioritize sleep and simple nervous system supports. Add nutrition shifts toward anti-inflammatory eating, then layer movement as capacity returns. Passive vagus-nerve supports can help when you are too depleted to do more. Jenny’s CIRS Healing Collective (https://cirshealingcollective.mn.co/landing) meets weekly to share practical tips, host guest experts, and reduce loneliness. Safe, validating connection supports the parasympathetic nervous system and helps people stay on the “healing track.” Jenny shares recoveries in her family from Lyme and mold injury, and a child’s neurodivergent symptoms easing after addressing environmental causes. Parents are encouraged to keep pressing for answers. ConclusionCIRS is fixable, and addressing it can dramatically change the trajectory of autoimmune symptoms. Start with a solid history, test what matters, remove exposures, and anchor sleep and nervous system care. Do less, but do it on the right track. Most of all, do not do this alone. Community and a clear plan make the path lighter and faster. Connect with Jenny JohnsonSimplified Wellness Designs: https://simplifiedwellnessdesigns.com The CIRS Healing Collective https://cirshealingcollective.mn.co/landingJenny Johnson is a leading expert in Chronic Inflammatory Response Syndrome (CIRS) and complex environmental illness. She is a Shoemaker Certified Coach, and drawing on years of clinical research and
In this groundbreaking conversation, Dr. Micah Yu speaks with retired rheumatologist Dr. Alfred Miller, who spent 40 years in practice and training at the Mayo Clinic. Dr. Miller shares his personal journey of discovering how Borrelia infections (often mislabeled as Lyme disease) may underlie many neurological and autoimmune conditions. From misdiagnosis in academic institutions to overlooked testing protocols, he reveals why conventional approaches often miss the mark — and how proper testing, treatment, and even unconventional therapies like bee venom and stem cells can change lives.Key TakeawaysWhy Borrelia infection is a “great imitator,” often misdiagnosed as ALS, MS, dementia, and other chronic diseasesThe flaws in current Lyme disease testing — and why omitting bands 31 & 34 on the Western blot leads to false negativesHow Borrelia’s 28-day reproductive cycle makes short-term antibiotic treatment ineffectiveThe role of cyst-busting medications and pulsed antibiotic protocols in treatmentCase studies: how Dr. Miller’s daughter-in-law lived seven years beyond a 4-month ALS prognosis after proper treatmentWhy Dr. Miller believes autoimmune disease is a mislabel, and many cases are driven by BorreliaFascinating integrative therapies, including bee venom’s ability to eradicate Borrelia and stem cell use in repairing neurodegenerative damageThe importance of specialized labs like IGeneX (U.S.) and ArminLabs (Europe) for accurate tick-borne disease testingThe link betweenBorrelia infections, which cause Lyme disease, and autoimmune disorders is a complex and evolving area of medical research. A Borrelia infection can trigger autoimmune responses in genetically predisposed individuals through several mechanisms, including molecular mimicry and the induction of chronic inflammation. The resulting immune dysfunction can lead to the development of specific autoimmune conditions, or it can produce symptoms that closely mimic those of autoimmune diseases. If you’ve ever wondered about the root causes of autoimmune disease, dementia, ALS, or rheumatoid arthritis, this episode will open your eyes to a different paradigm of medicine.Host Bio:Dr. Micah Yu is a board-certified integrative rheumatologist who blends conventional care with lifestyle and nutrition to help people reverse inflammation and live well with autoimmune disease. He is board certified in rheumatology, internal medicine, and lifestyle medicine, completed his residency and rheumatology fellowship at Loma Linda University, and earned his MD from Chicago Medical School along with master’s degrees in biomedical sciences and health care administration. He also completed fellowship training in integrative medicine at the University of Arizona. Dr. Yu co-founded Dr. Lifestyle in Newport Beach, California, where he sees patients locally and via telemedicine. He also co-hosts the Autoimmune Alchemy podcast with Dr. Melissa Mondala, bringing evidence, empathy, and practical tools to a global audience. His clinical perspective is informed by his own journey with autoimmune disease and by the results he has seen when patients pair targeted therapies with nutrition, sleep, movement, and stress resilience. Website: https://myautoimmunemd.com/
Description: Board-certified rheumatologist Dr. Aly Cohen joins Dr. Micah Yu to connect environmental exposures with inflammation and autoimmunity, then turn that science into practical, low-stress habits. From plastics and bisphenols to water, air, food, and personal-care choices, Dr. Cohen shares a simple framework to cut risk without overwhelm, and how she integrates these steps into rheumatology care and patient outcomes.What listeners will learn:Learn what “toxic load” means in plain language and why Dr. Cohen is seeing more young patients with autoimmune issues in her rheumatology practice. Discover smart ways to cut plastic exposure at home. Learn Dr. Cohen’s “4 As” roadmap to reduce exposures step by step so people make progress without burnout. Discover high-impact upgrades for water and why simple filtration can be a game changer across a lifetime. Learn how to choose and wash produce to lower pesticide residuesDiscover where endocrine-disrupting chemicals hide in cosmetics and personal careLearn practical changes for the kitchen, such as ways to remove microplasticsDiscover how Dr. Cohen pairs lifestyle and exposure reduction with standard rheumatology treatments to improve inflammation and quality of life.Short bio for Dr. Aly Cohen:Dr. Aly Cohen is a board-certified rheumatologist and integrative medicine physician with more than two decades of clinical experience. Her work focuses on how everyday environmental exposures influence hormones, immunity, and inflammation, and on translating that science into simple habits patients can sustain. In practice and public education, she teaches practical steps for safer water, food, air, and personal-care choices, and how to layer these into rheumatology care to support symptom control and long-term health. Dr. Aly Cohen’s Website: https://thesmarthuman.com/ Link to Dr. Cohen’s Book: “Detoxify: The Everyday Toxins Harming Your Immune System and How to Defend Against Them” Host Bio:Dr. Micah Yu is a board-certified integrative rheumatologist who blends conventional care with lifestyle and nutrition to help people reverse inflammation and live well with autoimmune disease. He is board certified in rheumatology, internal medicine, and lifestyle medicine, completed his residency and rheumatology fellowship at Loma Linda University, and earned his MD from Chicago Medical School along with master’s degrees in biomedical sciences and health care administration. He also completed fellowship training in integrative medicine at the University of Arizona. Dr. Yu co-founded Dr. Lifestyle in Newport Beach, California, where he sees patients locally and via telemedicine. He also co-hosts the Autoimmune Alchemy podcast with Dr. Melissa Mondala, bringing evidence, empathy, and practical tools to a global audience. His clinical perspective is informed by his own journey with autoimmune disease and by the results he has seen when patients pair targeted therapies with nutrition, sleep, movement, and stress resilience. Website: https://myautoimmunemd.com/
In this episode, Dr. Micah Yu and Dr. Melissa Mondala discuss one of the most overlooked aspects of autoimmune disease: mental health. With depression and anxiety affecting more than half of all autoimmune patients, the conversation explores the deep connection between the nervous system, trauma, inflammation, and long-term healing.Key Points:One in two people with autoimmune disease also has depression or anxiety.Mental health symptoms often appear years before autoimmune diagnosis.Emotional trauma, chronic stress, and neuroinflammation can all trigger or worsen autoimmune flares.The field of psycho-neuro-immunology explains how the brain, nervous system, and immune system interact.Childhood trauma (ACEs) significantly increases the risk of autoimmune conditions later in life.Early signs of depression and anxiety include sleep changes, appetite issues, mood swings, perfectionism, joint pain, rashes, and fatigue.Root Causes of Mental Health + Autoimmune Disease:Chronic stress and traumaHormonal fluctuations (e.g., PMS, menopause)Neurotransmitter imbalancesGut and microbiome dysfunctionEnvironmental toxins and heavy metalsNutrient deficiencies (zinc, B vitamins, etc.)Treatment Strategies:Nutrition: Whole foods rich in omega-3s, zinc, tryptophan, tyrosine, antioxidantsLifestyle: Daily movement, quality sleep, community connectionPractices: Meditation, prayer, breathwork, vagus nerve activation (humming, singing)Supplements (under guidance): SAM-e, L-theanine, ashwagandha, tryptophanPsychotherapy, psychosomatic healing, and nervous system retrainingFeatured Case Study:A 60-year-old woman with long-standing rheumatoid arthritis saw dramatic improvement in pain, energy, and inflammation after focusing on nervous system regulation, sleep, and mental wellness. Her care plan included vagus nerve stimulation and lifestyle changes. Within 3 months, she was pain-free, off prednisone, and considering a return to nursing. Her recovery also positively impacted her son, who struggled with mental health issues.Final Message:Healing is possible — even after years of trying. When diet and medications aren’t enough, it’s time to address mental health, trauma, and the nervous system. This episode reminds us that what feels emotional is often physical, and that support, persistence, and the right tools can make all the difference.Learn more or schedule a consult:Dr. Yu and Dr. Mondala’s clinic: https://myautoimmunemd.comDr. Yu on YouTube: My Autoimmune MDDr. Mondala on YouTube & Instagram: Dr. Melissa’s Kitchen
In this episode, Dr. Micah Yu and Dr. Melissa Mondala explore the rising epidemic of autoimmune disease. They unpack the root causes, early warning signs, and the whole-body approach needed for healing. They share personal clinical experiences, including a powerful success story using an anti-inflammatory protocol, and preview upcoming discussions on mental health, trauma, and psycho-neuro-immunology. The tone is both educational and hopeful, aimed at empowering patients and practitioners alike.🔹 Key Bullet Points:10% of the global population has autoimmune disease — and that number is rising.Autoimmunity affects multiple systems: rheumatology, neurology, endocrinology, GI, and beyond.These diseases are often missed or misdiagnosed, with patients cycling through many specialists.Women make up 80% of autoimmune cases.Autoimmune diseases include lupus, Hashimoto’s, RA, Crohn’s, type 1 diabetes, celiac, and more.Patients often develop multiple autoimmune conditions over time.Traditional medicine focuses on symptom suppression, not root cause resolution.🧠 Root Causes of Autoimmunity Discussed:Diet and lifestyle (nutrition, exercise, sleep)Environmental toxins (plastics, BPAs, PFAS, mold, heavy metals)Infections (Lyme, COVID, flu, mycoplasma, etc.)Medications and vaccines (as documented potential triggers)Genetics and epigeneticsChronic stress and traumaPsycho-neuro-immunology — the link between brain, immune system, and inflammation⚠️ Early Signs of Autoimmune Disease:Fatigue and brain fogRashes and joint painGI issues (like bloody stools)Oral/nasal ulcers, dry eyes/mouthHair lossThese signs are often subtle and systemic, making diagnosis difficult.🌿 Prevention & Healing:Emphasis on a functional and integrative medicine approachFocus on Anti-inflammatory nutrition, Lifestyle changes (movement, sleep, stress), Avoiding or reducing toxin exposure, and identifying and managing infectious triggersHealing is possible with small, consistent changes — often starting with food and mindset🧪 Patient Success Stories:Lupus Diagnosis: A patient went 5 years misdiagnosed by 10+ doctors. Dr. Yu correctly diagnosed lupus using labs and clinical intuition.RA Reversal with Diet: A long-term RA patient experienced a dramatic reduction in pain (from 9/10 to 1/10) in just one month using Dr. Yu’s anti-inflammatory protocol — no added meds or steroids.❤️ Mental Health Tie-In:50%+ of autoimmune patients struggle with depression and anxiety.Melissa introduces the concept of psycho-neuro-immunology: inflammation in the brain due to stress or trauma affects emotional regulation.Mental health support is crucial and will be discussed more deeply in the next episode.🔗 Resources Mentioned:Dr. Micah Yu’s YouTube: My Autoimmune MDDr. Melissa’s channel: Dr. Melissa’s Kitchen (healthy recipes)Clinic website: https://myautoimmunemd.com — based in Newport Beach, CA, offering telemedicine across the U.S.
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