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The Feldman Protocol

Author: Dave Feldman

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Dave Feldman hosts the Feldman Protocol, a long form, in-person podcast largely covering science, nutrition, and technology – with a lot of personal stories, interests and pop culture mixed in.
26 Episodes
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In this episode of The Feldman Protocol, what happens when a diet change succeeds where years of psychiatric treatment fall short? Matt Baszucki, metabolic mental health advocate and YouTube creator, makes the case from lived experience, discussing bipolar disorder, psychosis, ketogenic therapy, medication tapering, carnivore, and why metabolic approaches still struggle to break into mainstream psychiatry.🔥 This episode is sponsored by us -- Own Your Labs 👉 https://ownyourlabs.com/tfp/26 Private blood testing services🩸Over 300 blood tests💰 Extremely affordable❤️ We love our customers(Yes, we are literally funding the entire podcast from our own company -- so if you want to show your support, keep getting your private blood testing through our service. Thank you! 🙏)🔗 CONNECT WITH DAVE FELDMAN:Main Channel: https://youtube.com/@realDaveFeldmanX/Twitter: https://x.com/realDaveFeldmanInstagram: https://instagram.com/realDaveFeldmanWebsite: https://thefeldmanprotocol.com⏱ Chapters3:06 – Charlie Foundation origin9:46 – Memory during psychosis16:49 – Berkeley relapse spiral23:23 – The first real insight30:50 – Dave’s mood crash story37:57 – When keto clicked44:55 – Why tapers take years51:57 – How trials get framed58:43 – Carnivore and withdrawal1:05:43 – Keto as one option1:12:42 – A movement takes shape1:19:39 – Why adoption lags1:26:40 – Can AI fix medicine?1:33:45 – The AGI risk1:40:36 – Panic and moral scares1:47:50 – Power under AGI1:54:29 – A phone-shaped dystopia2:01:33 – What nature restores2:08:28 – Why meditation is hard2:15:25 – Walking into presence2:22:22 – The inbox never stops2:29:33 – Dating apps and the 80/202:36:18 – Marriage then vs now2:43:22 – Modern confusion loops2:50:19 – Fear of approaching women2:57:17 – Victim culture debate3:04:12 – AI and stealth censorship3:11:09 – Crisis and free speech3:18:07 – Why sports hit hard3:25:04 – Tribal identity in sports3:32:07 – Crowd emotion in motion3:39:05 – Teaching resilience early3:46:04 – Books then vs now3:52:56 – Streaming and story decline3:59:59 – Good AI vs bad AI#FeldmanProtocol #DaveFeldman #MattBaszucki #MentalHealth #MetabolicHealth #KetogenicDiet #Carnivore #BipolarDisorder #Psychiatry #Nutrition #LongformPodcast #PodcastInterview #Wellness #HealthResearch
In this episode of The Feldman Protocol, can heart disease prevention be asking the wrong question? Dave sits down with Philip Ovadia, MD, cardiothoracic surgeon, as the guest makes the case for looking beyond LDL alone. They discuss bypass surgery, why cholesterol-lowering hasn’t erased heart disease, insulin resistance, trial design, statins and PCSK9 drugs, real-food diets, CGMs, and how clinicians think about risk in practice.🔥 This episode is sponsored by us -- Own Your Labs 👉 https://ownyourlabs.com/tfp/25 Private blood testing services🩸Over 300 blood tests💰 Extremely affordable❤️ We love our customers(Yes, we are literally funding the entire podcast from our own company -- so if you want to show your support, keep getting your private blood testing through our service. Thank you! 🙏)🔗 CONNECT WITH DAVE FELDMAN:Main Channel: https://youtube.com/@realDaveFeldmanX/Twitter: https://x.com/realDaveFeldmanInstagram: https://instagram.com/realDaveFeldmanWebsite: https://thefeldmanprotocol.com⏱ Chapters3:04 – Dave sets the frame9:41 – The preacher’s fallacy16:22 – What else is cholesterol for?23:02 – FOURIER stopped early29:41 – When treatment still fails36:22 – Who benefits from treatment?42:59 – The patient mindset49:40 – Building a new practice56:21 – Insulin in the hospital1:02:58 – Cholesterol stays central1:09:39 – LDL vs A1C tradeoffs1:16:20 – Politics and processed food1:22:58 – Plants, meat, and real food1:29:38 – One diet won’t fit all1:36:20 – CGMs and self-testing1:43:01 – Why Ovadia chose surgery1:49:40 – The challenge of bypass1:56:18 – VCAM and atherosclerosis2:02:57 – Surgical feedback loops2:09:37 – Coming out of surgery2:16:17 – Arguments from medicine2:22:56 – Low-carb doctor network2:29:36 – Podcasting in person2:36:18 – The diabetic pandemic2:42:58 – Why disbelief happens2:49:36 – Shift the focus2:56:18 – ApoB takes center stage3:02:58 – Small dense LDL debate3:09:35 – Patients need clarity3:16:16 – What the scans show3:22:58 – Making sense of the paper3:29:36 – Reading vessel segments3:36:18 – What 100 hearts can show3:42:54 – LDL as a distraction3:49:36 – Arguing the phenotype#FeldmanProtocol #DaveFeldman #PhilipOvadia #HeartHealth #CardiothoracicSurgery #MetabolicHealth #InsulinResistance #LDL #ApoB #LowCarb #RealFood #CGM #Cardiology #PreventiveHealth #NutritionScience #Podcast
In this episode of The Feldman Protocol, what does it take to turn a dense cholesterol debate into a film people can actually follow? Dave talks with Jennifer Isenhart, documentary director and writer, about making *Cholesterol Code*, translating complex science for a lay audience, weaving in personal stories, navigating four years of production twists, and reshaping the film as new data emerged. 🔥 This episode is sponsored by us -- Own Your Labs 👉 https://ownyourlabs.com/tfp/24 Private blood testing services🩸Over 300 blood tests💰 Extremely affordable❤️ We love our customers(Yes, we are literally funding the entire podcast from our own company -- so if you want to show your support, keep getting your private blood testing through our service. Thank you! 🙏)🔗 CONNECT WITH DAVE FELDMAN:Main Channel: `https://youtube.com/@realDaveFeldman`X/Twitter: `https://x.com/realDaveFeldman`Instagram: `https://instagram.com/realDaveFeldman`Website: `https://thefeldmanprotocol.com`⏱ Chapters3:01 – Trailer Reactions6:13 – First Data Arrives9:22 – Cholesterol Fear12:35 – Writing for Laypeople15:46 – Editing Is Massive18:58 – Recutting the Film22:08 – Creative Collaboration25:21 – Building Interview Scenes28:32 – Graphics on a Budget31:44 – Landing Bernstein34:56 – Keto in Epilepsy38:06 – Family Pushback41:18 – Parents Under Fire44:27 – Mammogram of the Heart47:40 – Why Age Matters50:50 – Surprises in the Research54:04 – Questions They Missed57:14 – Interviewing Together1:00:23 – Local TV Origins1:03:38 – Travel Channel Pitch1:06:47 – Betting on Fat Fiction1:09:57 – Costco Takes Off1:13:12 – Streaming Math1:16:20 – Taking on New Topics1:19:33 – Nina Teicholz Tribute1:22:45 – Self-Funding Reality1:25:55 – Global Shoot Plans1:29:07 – Covid Shuts It Down1:32:19 – Low-Carb Conference Boom1:35:31 – Why This Film Came Next1:38:41 – The 10% Rule1:41:52 – Better Experiments1:45:04 – Staying Open-Minded1:48:16 – Final Export Panic1:51:28 – Bernstein’s Lost Viewing#FeldmanProtocol #DaveFeldman #JenniferIsenhart #CholesterolCode #DocumentaryFilm #LowCarb #Keto #MetabolicHealth #ScienceCommunication #IndependentFilm #HealthDocumentary #NutritionScience #FilmMaking #CitizenScience
In this episode of The Feldman Protocol, what happens when a midlife dietary change collides with decades of diagnosis, stigma, and trial-and-error? Guest Robyn Dobbins (lived-experience advocate, podcast host, health coach, and community coordinator at the nonprofit Metabolic Collective) makes the case for why personal narratives matter in metabolic mental-health advocacy—covering early symptoms, postpartum struggles, routines and relationships, low-carb/keto tradeoffs, community building, and how cholesterol conversations show up along the way.🔥 This episode is sponsored by us -- Own Your Labs 👉 https://ownyourlabs.com/tfp/23 Private blood testing services🩸Over 300 blood tests💰 Extremely affordable❤️ We love our customers(Yes, we are literally funding the entire podcast from our own company -- so if you want to show your support, keep getting your private blood testing through our service. Thank you! 🙏)🔗 CONNECT WITH DAVE FELDMAN:Main Channel: `https://youtube.com/@realDaveFeldman`X/Twitter: `https://x.com/realDaveFeldman`Instagram: `https://instagram.com/realDaveFeldman`Website: `https://thefeldmanprotocol.com`⏱ Chapters3:00 – High school stigma 9:01 – On the spectrum 15:07 – When words hit wrong 21:09 – Sister’s friend group 27:12 – Could you talk about it? 33:16 – Routines break down 39:19 – Hindsight reframes it 45:20 – I don’t know anyone 51:25 – “This sounds like me” 57:26 – The reality of it 1:03:31 – Foreshadowing 1:09:34 – Training goes sideways 1:15:37 – Separate category? 1:21:36 – Why he moved 1:27:44 – Work with a doctor 1:33:43 – Not all sunshine 1:39:48 – Self-diagnosing 1:45:50 – Sweet potato moment 1:51:53 – Who is this for? 1:57:57 – Prioritize mental health 2:04:01 – Trust, at the top 2:10:03 – Careful with labels 2:16:05 – “Did they test that?” 2:22:05 – Costs ballooning 2:28:13 – Why it’s medical 2:34:15 – “So if I just…?” 2:40:15 – How long to feel it? 2:46:20 – Baseline changed 2:52:22 – Fear of outcomes 2:58:27 – LMHR status 3:04:33 – Ask people directly 3:10:34 – Before GLP-1s 3:16:36 – It felt similar 3:22:37 – Cholesterol Code doc 3:28:42 – Scientists & doctors #FeldmanProtocol #DaveFeldman #RobynDobbins #Podcast #PodcastInterview #MentalHealthAdvocacy #MetabolicHealth #LowCarb #KetogenicLifestyle #HealthCoach #Storytelling #Nonprofit #CommunityBuilding #Nutrition #Wellness #CholesterolCode #MetabolicCollective
In this episode of The Feldman Protocol, what happens when a personal health experiment turns into a public-facing education project? Guest makes the case for practical, data-minded self-tracking while navigating online narratives and everyday constraints. Dave and Jenny Mitich (nutrition educator and author of *The Complete Carnivore*) discuss glucose monitoring, protein-to-fat adjustments, testing prep, content creation, parenting and culture, and why incentives and data collection methods shape what people think they “know.”🔥 This episode is sponsored by us -- Own Your Labs 👉 https://ownyourlabs.com/tfp/22 Private blood testing services🩸Over 300 blood tests💰 Extremely affordable❤️ We love our customers(Yes, we are literally funding the entire podcast from our own company -- so if you want to show your support, keep getting your private blood testing through our service. Thank you! 🙏)🔗 CONNECT WITH DAVE FELDMAN:Main Channel: https://youtube.com/@realDaveFeldmanX/Twitter: https://x.com/realDaveFeldmanInstagram: https://instagram.com/realDaveFeldmanWebsite: https://thefeldmanprotocol.com⏱ Chapters3:02 – Jenny’s pivot year 9:28 – Values & food choices 15:55 – Travel and lifestyle reset 22:24 – Postpartum wake-up call 28:50 – Why health journeys spread 35:22 – Launch logistics and promos 41:48 – What felt different early on 48:15 – Reading glucose patterns 54:44 – Testing prep and timing 1:01:11 – Protein vs fat balance 1:07:37 – Hunger cues and needs 1:14:06 – Online narratives shift 1:20:32 – Community dynamics 1:27:01 – What the film covered 1:33:28 – Red flags to watch for 1:39:57 – Panels, talks, signings 1:46:24 – Future books and plans 1:52:51 – Cooking: love vs duty 1:59:21 – Untangling cause and effect 2:05:48 – Pricing and accessibility 2:12:16 – Reality-checking progress 2:18:42 – Family history context 2:25:09 – Generational framing 2:31:40 – Kids, games, and culture 2:38:06 – Modern dissatisfaction 2:44:32 – Teaching discernment 2:50:59 – Breaking family cycles 2:57:26 – Content creator pressures 3:03:55 – Empathy and lived experience 3:10:22 – Shortcuts people take 3:16:50 – Salt talk and blood pressure 3:23:17 – Food identity and choices 3:29:47 – Nuance and caveats 3:36:16 – Interpreting “bad” markers 3:42:41 – Incentives and better data #FeldmanProtocol #DaveFeldman #JennyMitich #Podcast #LongFormPodcast #Interview #CreatorEconomy #Parenting #Lifestyle #NutritionEducation #GlucoseMonitoring #DataLiteracy #CitizenScience #Research #WellnessConversation
In this episode of The Feldman Protocol, Greg Mushen, a longtime technology and product leader turned independent health researcher, makes the case that disciplined thinking from Silicon Valley can meaningfully inform nutrition and metabolic health. The discussion also directly engages with debates raised by the Keto-CTA study, using it as a case example to examine data transparency, scientific criticism, and decision-making under uncertainty—alongside metabolic testing innovation, walking versus high-intensity exercise, protein prioritization, and Greg’s own body recomposition—through a skeptical, analytical lens.🔥 This episode is sponsored by us -- Own Your Labs 👉 https://ownyourlabs.com/tfp/21 Private blood testing services🩸Over 300 blood tests💰 Extremely affordable❤️ We love our customers(Yes, we are literally funding the entire podcast from our own company -- so if you want to show your support, keep getting your private blood testing through our service. Thank you! 🙏)🔗 CONNECT WITH DAVE FELDMAN:Main Channel: `https://youtube.com/@realDaveFeldman`X/Twitter: `https://x.com/realDaveFeldman`Instagram: `https://instagram.com/realDaveFeldman`Website: `https://thefeldmanprotocol.com`⏱ Chapters3:42 – Data gaps in modern science10:02 – Greg’s tech career origins17:01 – Dot-com crash lessons24:08 – Product management under pressure31:10 – Data vs intuition in products38:12 – Toxic positivity at work45:30 – Internal honesty and feedback52:40 – Health wake-up moment59:55 – Weight, aging, and motivation1:07:10 – Mold exposure and health1:14:21 – Walking as a strategy1:21:30 – Step counts and fat loss1:28:47 – Protein targets explained1:35:50 – Satiety and energy balance1:42:30 – Before-and-after perspective1:49:40 – Training consistency1:56:20 – Hiring a coach2:03:10 – Volume and hypertrophy2:10:30 – Sustainable habits2:17:20 – Aging and strength2:24:30 – Transparency in research2:31:40 – Fraud and oversight2:38:30 – Whistleblowers in science2:55:30 – Where to find Greg3:01:56 – Final reflections and wrap#FeldmanProtocol #DaveFeldman #GregMushen #MetabolicHealth #ProductThinking #DataTransparency #ProteinIntake #WalkingForHealth #StrengthTraining #HealthAndTech
In this episode of The Feldman Protocol, a core question hangs over the conversation: how did so many clinicians and patients miss low-carb interventions for so long? Dave sits down with Doug Reynolds, founder of Low Carb USA and president of the Society of Metabolic Health Practitioners, as the guest makes the case for carbohydrate reduction in chronic disease, practitioner education gaps, cultural food traditions, patient-driven change, conference-based knowledge sharing, and why engineers often follow data over authority.🔥 This episode is sponsored by us -- Own Your Labs 👉 https://ownyourlabs.com/tfp/20 Private blood testing services🩸Over 300 blood tests💰 Extremely affordable❤️ We love our customers(Yes, we are literally funding the entire podcast from our own company -- so if you want to show your support, keep getting your private blood testing through our service. Thank you! 🙏)🔗 CONNECT WITH DAVE FELDMAN:Main Channel: `https://youtube.com/@realDaveFeldman`X/Twitter: `https://x.com/realDaveFeldman`Instagram: `https://instagram.com/realDaveFeldman`Website: `https://thefeldmanprotocol.com`⏱ Chapters3:02 – Fat, food, and first doubts7:05 – Preserving meat traditions11:02 – Cooking as commitment15:03 – Culture vs convenience19:02 – Career detours and Amway24:03 – Discovering ketones29:02 – First ribeye moment34:02 – Engineers and data trust39:05 – Questioning guidelines45:02 – Forums over authority51:21 – Conferences as catalysts57:10 – Practitioner hesitation1:02:28 – Patients leading change1:08:15 – Education gaps in care1:15:40 – Cultural resistance1:21:39 – Scaling conferences1:27:10 – Screening ideas1:33:00 – Community momentum1:39:40 – Measuring success1:45:20 – Clinical anecdotes1:51:21 – Sharing unfinished work1:56:30 – Patient empowerment2:01:39 – Insulin outcomes shift2:02:28 – Lifestyle over mandates2:03:56 – Why the message spreads#FeldmanProtocol #DaveFeldman #DougReynolds #LowCarbUSA #MetabolicHealth #PodcastInterview #HealthDiscussion #SciencePodcast #NutritionTalk #PatientCare #MedicalEducation
In this episode of The Feldman Protocol, a provocative question anchors the conversation: how much of cardiovascular risk is about cholesterol itself versus the context it operates in? Guest **Josh Wageman, DPT, PA-C, PhD**—a clinical lipid specialist and researcher—makes the case for using metaphor, metabolic health, and imaging to think differently about risk. The discussion spans coronary calcium scoring, lipid particles, insulin and inflammation, endurance training extremes, neurodegeneration, and why communicating science clearly actually matters. 🔥 This episode is sponsored by us -- Own Your Labs 👉 https://ownyourlabs.com/tfp/19 Private blood testing services🩸Over 300 blood tests💰 Extremely affordable❤️ We love our customers(Yes, we are literally funding the entire podcast from our own company -- so if you want to show your support, keep getting your private blood testing through our service. Thank you! 🙏)🔗 CONNECT WITH DAVE FELDMAN:Main Channel: `https://youtube.com/@realDaveFeldman`X/Twitter: `https://x.com/realDaveFeldman`Instagram: `https://instagram.com/realDaveFeldman`Website: `https://thefeldmanprotocol.com`⏱ Chapters3:00 – Why metaphors matter in medicine9:32 – Josh’s unconventional training path15:48 – Overtraining, illness, and collapse21:56 – Thyroid failure and recovery28:10 – Learning endocrinology the hard way34:42 – From PT to lipid specialist41:05 – Why lipids became the focus47:22 – Humor as a teaching tool53:40 – Writing the “lipid neighborhood”1:00:02 – Four pillars of metabolic health1:06:18 – Insulin and context over numbers1:12:35 – Inflammation isn’t one thing1:18:52 – Drugs as a risk factor1:25:14 – Cholesterol doesn’t live on paper1:31:28 – CAC as a reality check1:37:44 – Zero CAC and residual risk1:43:59 – Genetics vs lifestyle1:50:12 – ApoB’s necessary role1:56:27 – Why plaque still forms2:02:41 – Extreme endurance and CAC2:08:55 – When fitness backfires2:15:10 – Imaging vs biomarkers2:21:26 – Dementia and lipid biology2:27:40 – Neurodegeneration as frontier2:33:55 – Teaching clinicians differently2:40:08 – Credentials vs trust2:46:22 – Patient-first frameworks2:52:36 – Science communication failures2:58:49 – Measuring what matters3:04:55 – Meaning beyond metrics3:11:10 – Legacy and patient impact3:15:42 – Where Josh wants research to go3:18:43 – Closing thoughts and gratitude#FeldmanProtocol #DaveFeldman #JoshWageman #Lipids #Cholesterol #MetabolicHealth #ApoB #CACScore #Endocrinology #PreventiveCardiology #HealthCommunication
In this episode of The Feldman Protocol, Dave asks: what happens when a fertility specialist-turned-health thinker questions nutrition narrative? Guest Robert Kiltz, MD, makes the case for animal-based diets, metabolic flexibility, mindset, faith and medicine, clinical experience vs. guidelines, and the role of community. The conversation ranges from physiology and lipid metabolism to entrepreneurship, skepticism, and personal practice — always with an eye toward evidence and open inquiry.🔥 This episode is sponsored by us -- Own Your Labs 👉 https://ownyourlabs.com/tfp/18 Private blood testing services🩸Over 300 blood tests💰 Extremely affordable❤️ We love our customers(Yes, we are literally funding the entire podcast from our own company -- so if you want to show your support, keep getting your private blood testing through our service. Thank you! 🙏)🔗 CONNECT WITH DAVE FELDMAN:Main Channel: https://youtube.com/@realDaveFeldmanX/Twitter: https://x.com/realDaveFeldmanInstagram: https://instagram.com/realDaveFeldmanWebsite: https://thefeldmanprotocol.com⏱ Chapters3:00 – Opening themes & big questions6:38 – Robert’s clinical background10:17 – Nutrition beliefs under the microscope13:55 – Defining metabolic health17:34 – Mindset, faith, and medicine21:12 – Carnivore experiences & context24:51 – LDL, risk, and interpretation28:29 – Citizen science in practice32:08 – Physiology vs. guidelines35:46 – The liver’s central role39:25 – Energy substrates explored43:03 – Food, behavior, and culture46:42 – Clinical anecdotes & caution50:20 – Lipids and metabolism debate53:59 – Diet, hormones, and stress57:37 – Weight, appetite, & satiety1:01:16 – Exercise, fitness, longevity1:04:54 – Medical orthodoxy pressures1:08:33 – Risk-benefit & uncertainty1:12:11 – Lab markers & context1:15:50 – Entrepreneurship & medicine1:19:28 – Patient communication style1:23:07 – Spirituality & health lens1:26:45 – Preventive care realities1:30:24 – Evidence vs. experience1:34:02 – Personal responsibility1:37:41 – Critics & open inquiry1:41:19 – Careers, courage, & change1:44:58 – Community & service1:48:36 – Learning from disagreement1:52:15 – Practical takeaways1:55:53 – Health as a journey1:59:32 – Gratitude & perspective2:03:10 – Final reflections2:06:49 – Closing thoughts & thanks#FeldmanProtocol #DaveFeldman #RobertKiltz #podcast #nutrition #healthjourney #openinquiry #metabolism #lowcarbcommunity #wellnessdiscussion #citizenscience #medicalethics #mindsetmatters #healthydebate #scienceconversation
In this episode of The Feldman Protocol, Dave asks a blunt question: is modern medicine structurally aligned against prevention? Guest **Emily Kaplan**, investigative science journalist and co-founder of the Broken Science Initiative, makes the case that incentives, not evidence, increasingly shape medical practice. They discuss conflicts of interest in research, the reproducibility crisis, metabolic health and lifestyle medicine, GLP-1 drugs, nutrition education gaps, and why outcomes often matter less than headlines.🔥 This episode is sponsored by us -- Own Your Labs 👉 https://ownyourlabs.com/tfp/17 Private blood testing services🩸Over 300 blood tests💰 Extremely affordable❤️ We love our customers(Yes, we are literally funding the entire podcast from our own company -- so if you want to show your support, keep getting your private blood testing through our service. Thank you! 🙏)🔗 CONNECT WITH DAVE FELDMAN:Main Channel: `https://youtube.com/@realDaveFeldman`X/Twitter: `https://x.com/realDaveFeldman`Instagram: `https://instagram.com/realDaveFeldman`Website: `https://thefeldmanprotocol.com`⏱ Chapters3:01 – Broken Science explained6:02 – Lifestyle vs polypharmacy9:03 – Medical school nutrition gaps12:13 – Incentives in healthcare15:57 – Sugar and cancer framing18:36 – Trial endpoints questioned21:11 – GLP-1s and tradeoffs24:01 – Weight loss vs health26:21 – Personal choice in diet29:02 – Early insulin signals32:25 – Publishing and paywalls35:10 – Journalism vs academia38:42 – Conflicts of interest42:08 – Peer review problems45:44 – Delays in publication49:12 – Who funds research52:48 – Education as prevention56:19 – Reproducibility crisis59:01 – Replication failures1:02:28 – Meta-analysis limits1:05:30 – Industry influence1:08:54 – What gets taught1:12:40 – Transparency gaps1:16:33 – Accountability in science1:38:20 – Where reform starts1:40:14 – Transparency vs incentives1:52:38 – Publishing power dynamics2:05:11 – Peer review bottlenecks2:17:44 – Conflicts without disclosure2:30:06 – Career risk in dissent2:42:31 – Nutrition sidelined again2:54:57 – Prevention vs treatment3:00:14 – N-of-1 data debate3:12:48 – Prospective study limits3:25:22 – Community-driven research3:37:49 – IRB and self-selection3:50:17 – Data ownership questions4:02:41 – Tech platforms for science4:10:06 – Scaling transparency4:15:32 – Reforming research norms4:18:54 – Public accountability4:20:41 – Communicating uncertainty4:22:53 – Where to find Emily4:23:05 – Final reflections#FeldmanProtocol #DaveFeldman #EmilyKaplan #BrokenScience #MedicalResearch #ScienceJournalism #MetabolicHealth #NutritionEducation #HealthcareIncentives #ReproducibilityCrisis #PreventiveMedicine #PublicHealth
In this episode of The Feldman Protocol, a central question hangs over the conversation: what actually causes a heart attack when standard risk markers look “normal”? Guest Dr. Stephen Hussey, DC (functional medicine practitioner focused on cardiovascular disease), makes the case for re-examining core assumptions about heart disease. Topics include plaque vs. risk, LDL cholesterol, CAC scoring, stress physiology, hydration, type 1 diabetes, endurance exercise, and alternative mechanisms behind myocardial infarction. 🔥 This episode is sponsored by us -- Own Your Labs 👉 https://ownyourlabs.com/tfp/16 Private blood testing services🩸Over 300 blood tests💰 Extremely affordable❤️ We love our customers(Yes, we are literally funding the entire podcast from our own company -- so if you want to show your support, keep getting your private blood testing through our service. Thank you! 🙏)🔗 CONNECT WITH DAVE FELDMAN:Main Channel: https://youtube.com/@realDaveFeldmanX/Twitter: https://x.com/realDaveFeldmanInstagram: https://instagram.com/realDaveFeldmanWebsite: https://thefeldmanprotocol.com⏱ Chapters3:06 – Why heart cells don’t regenerate8:12 – Marathon runners & plaque paradox13:48 – Introducing Dr. Stephen Hussey18:37 – Type 1 diabetes & heart risk23:54 – Diet changes and inflammation29:35 – Low-carb, keto, and carnivore paths35:10 – Insulin, carbs, and standard care40:52 – Fear of ketosis vs ketoacidosis46:18 – Discovering lipid anomalies51:40 – Rejecting statins early on57:12 – Elevated LDL in context1:02:44 – Writing a heart disease book1:08:30 – Widowmaker heart attack story1:14:06 – CAC score of zero explained1:19:42 – Stress, dehydration, and triggers1:25:18 – The moment symptoms began1:30:54 – Cath lab and LAD blockage1:36:20 – Stent placement and relief1:41:58 – Was it plaque or clot?1:47:30 – Alternative MI mechanisms1:53:12 – Parasympathetic nervous system1:58:54 – Vasa vasorum hypothesis2:04:36 – Transcytosis and ApoB2:10:18 – Endothelial injury models2:15:44 – Exercise-linked occlusions2:21:06 – Post-MI medical advice2:26:30 – Five lifelong medications?2:31:48 – Blood pressure overshoot2:37:22 – Blood thinners and stents2:42:54 – Re-evaluating cholesterol blame2:48:10 – What medicine gets wrong2:53:36 – Prevention beyond LDL2:58:52 – How Stephen works with clients#FeldmanProtocol #DaveFeldman #StephenHussey #HeartHealth #Cardiology #MetabolicHealth #Cholesterol #LDL #Atherosclerosis #CACScore #Type1Diabetes #ExerciseScience
In this episode of The Feldman Protocol, we ask: What happens when clinical guidelines collides with messy real-world outcomes? Guest Bret Scher, MD, makes the case for rethinking metabolic health, evidence hierarchies, clinical incentives, LDL interpretation, ketogenic therapies, guideline rigidity, psychiatric applications of metabolic interventions, and his own evolution from cardiologist to medical director in the metabolic-health space.🔥 This episode is sponsored by us -- Own Your Labs 👉 https://ownyourlabs.com/tfp/15 Private blood testing services🩸Over 300 blood tests💰 Extremely affordable❤️ We love our customers(Yes, we are literally funding the entire podcast from our own company -- so if you want to show your support, keep getting your private blood testing through our service. Thank you! 🙏)🔗 CONNECT WITH DAVE FELDMAN:Main Channel: https://youtube.com/@realDaveFeldmanX/Twitter: https://x.com/realDaveFeldmanInstagram: https://instagram.com/realDaveFeldmanWebsite: https://thefeldmanprotocol.com⏱ Chapters3:00 – How clinicians lose objectivity13:57 – When lifestyle advice keeps failing24:55 – The social cost of challenging LDL norms35:52 – Epidemiology’s limits in nutrition46:50 – Why “healthy user bias” distorts data57:47 – The Diet Doctor era and its impact1:08:45 – Red meat, risk, and uncertain evidence1:19:42 – Predicting outcomes vs. assuming causality1:30:40 – The guidelines problem inside medicine1:41:37 – Why patients succeed outside the system1:52:35 – Multiple dietary paths, not one dogma2:03:32 – How personality shapes dietary fit2:14:30 – From keto diet to medical therapy2:25:27 – The mindset shift toward low carb2:36:25 – How podcasting changed Bret’s trajectory2:47:22 – The origin story of Metabolic Mind2:58:20 – Metabolic psychiatry’s scientific emergence3:09:17 – Coalition for Metabolic Health vision#FeldmanProtocol #DaveFeldman #BretScher #MetabolicHealth #Keto #LowCarb #Cardiology #EvidenceBased #NutritionScience #LDL #Epidemiology #CriticalThinking #MetabolicPsychiatry #HealthPolicy #MedicalGuidelines #Wellness #MetabolicMind #Podcast #ScienceDiscussion
In this episode of The Feldman Protocol, what if a single overlooked nutrient could meaningfully alter how we think about chronic illness? Guest Dr. Darren Schmidt (DC, nutrition-focused clinician) makes the case for the role of B1 deficiency, discusses environmental toxic exposures, explores mitochondrial dysfunction, and examines lactic acidosis as a framework for understanding complex disease patterns. We also discuss metabolic pathways, autonomic issues, and how clinical observations can challenge conventional assumptions.🔥 This episode is sponsored by us -- Own Your Labs 👉 https://ownyourlabs.com/tfp/14 Private blood testing services🩸Over 300 blood tests💰 Extremely affordable❤️ We love our customers(Yes, we are literally funding the entire podcast from our own company -- so if you want to show your support, keep getting your private blood testing through our service. Thank you! 🙏)🔗 CONNECT WITH DAVE FELDMAN:Main Channel: https://youtube.com/@realDaveFeldmanX/Twitter: https://x.com/realDaveFeldmanInstagram: https://instagram.com/realDaveFeldmanWebsite: https://thefeldmanprotocol.com⏱ Chapters3:00 – Early health shifts4:58 – First exposure incident6:56 – Discovering toxicity impacts8:54 – Mold and respiratory effects10:52 – Gas leak symptoms escalate12:50 – ER visit and missed signals14:48 – Autonomic dysfunction clues16:46 – Testing high-dose B118:44 – Rapid symptom relief20:42 – Mechanisms Dave examines22:40 – High-calorie malnutrition idea24:38 – Clinical responses to B126:36 – RCT possibilities28:34 – Origins of lactic acidosis theory30:32 – How toxins affect oxygen use32:30 – Capillary dilation mechanics34:28 – Mitochondrial parallels36:26 – Detox strategies overview38:24 – Dave’s metabolic framework40:22 – Pyruvate and lactate shifts42:20 – Rate limiters in metabolism44:18 – Nervous system involvement46:16 – Expanding symptom categories48:14 – Environmental drivers of illness50:12 – Mold detection and evidence52:10 – Radon and other exposures54:08 – Chronic illness complexity56:06 – Personal learning through crises58:04 – Rediscovering past medical history1:00:02 – Nutrient fortification lessons#FeldmanProtocol #DaveFeldman #DarrenSchmidt #metabolism #mitochondria #chronicillness #environmentalhealth #nutritionscience #lactate #thiamine #functionalhealth #biochemistry #healthpodcast #keto #lowcarb #detox #mitochondrialfunction
In this episode of The Feldman Protocol, can you truly build muscle and maintain health with just 15 minutes of exercise twice a week? Dave chats with Ben Bocchicchio, PhD in Exercise Physiology and Health, who makes the case for slow-motion resistance training as the ultimate efficiency hack. Guest explores mitochondrial optimization through high-intensity exercise, addresses middle-age workout mistakes, discusses low-carb nutrition strategies spanning five decades, and challenges conventional fitness wisdom with his revolutionary "safe emergency" training philosophy.🔥 This episode is sponsored by us -- Own Your Labs 👉 https://ownyourlabs.com/tfp/13 Private blood testing services🩸Over 300 blood tests💰 Extremely affordable❤️ We love our customers(Yes, we are literally funding the entire podcast from our own company -- so if you want to show your support, keep getting your private blood testing through our service. Thank you! 🙏)🔗 CONNECT WITH DAVE FELDMAN:Main Channel: https://youtube.com/@realDaveFeldmanX/Twitter: https://x.com/realDaveFeldmanInstagram: https://instagram.com/realDaveFeldmanWebsite: https://thefeldmanprotocol.com⏱ Chapters3:14 – Introduction and athletic background12:37 – Uncle Tony and Charles Atlas connection25:42 – Nautilus machines and slow training origins40:18 – Muscle fiber recruitment and intensity58:23 – Common middle-age exercise mistakes1:15:47 – Metabolic benefits of resistance training1:32:19 – Nutrition philosophy and 50-year approach1:50:33 – Food addiction and behavioral change2:08:56 – AI and personalized health predictions2:22:41 – Energy metabolism and final thoughts#FeldmanProtocol #DaveFeldman #BenBocchicchio #SlowTraining #ResistanceTraining #ExercisePhysiology #Mitochondria #LowCarb #Nutrition #MetabolicHealth #HighIntensityTraining #Fitness #Aging #Sarcopenia #HealthSpan #Longevity #BloodTesting #Science
In this episode of The Feldman Protocol, special guest Mike Mutzel explores groundbreaking research on the immune system, GLP-1, the gut microbiome and lean mass hyper-responders. They deep dive on the Lipid Energy Model, atherosclerosis mechanisms, immune system interactions, coronary artery imaging data, and conventional cardiovascular risk paradigms in metabolic health.🔥 This episode is sponsored by us -- Own Your Labs 👉 https://ownyourlabs.com/tfp/12 Private blood testing services🩸Over 300 blood tests💰 Extremely affordable❤️ We love our customers(Yes, we are literally funding the entire podcast from our own company -- so if you want to show your support, keep getting your private blood testing through our service. Thank you! 🙏)🔗 CONNECT WITH DAVE FELDMAN:Main Channel: https://youtube.com/@realDaveFeldmanX/Twitter: https://x.com/realDaveFeldman Instagram: https://instagram.com/realDaveFeldmanWebsite: https://thefeldmanprotocol.com⏱ Chapters3:01 – Introduction and Mike's background9:14 – Medicine and nutrition evolution17:44 – Mindful eating and GLP-1 connections25:00 – Dave's cholesterol discovery story31:42 – Understanding lipid trafficking physics40:18 – Endothelial dysfunction and inflammation49:00 – LDL oxidation and modification theories58:23 – Atherosclerosis as immune response1:05:47 – Blood viscosity and cardiovascular risk1:15:19 – Self-censorship in scientific discourse1:25:33 – Continual exposure hypothesis debate1:32:19 – Own Your Labs citizen science project1:40:58 – Cholesterol paradox in aging populations1:50:33 – Metabolic health vs inflammation2:00:12 – Radiation concerns with CT angiograms2:08:56 – Triglycerides and ketogenic metabolism2:18:47 – Study results and mainstream response2:22:41 – Final thoughts and future research#FeldmanProtocol #DaveFeldman #DaveFeldmanGuest #LipidEnergyModel #LeanMassHyperResponder #LMHR #CholesterolResearch #MetabolicHealth #LDLCholesterol #CoronaryArteryImaging #ApoB #CardiovascularHealth #KetoResearch #CitizenScience #OwnYourLabs #LipidParticles #Atherosclerosis #EndothelialFunction #BloodViscosity #TriglyceridesTolerance #LPA
In this episode, Dave sits down with Austin, a metabolic data enthusiast and early adopter of continuous glucose monitoring (CGM) who brings a fascinating blend of self-experimentation, performance optimization, and deep curiosity about human physiology. From endurance training to dietary tracking, Austin shares his journey through the data-driven side of health — how he uses CGM, heart rate, and nutrient timing to reveal the body’s hidden patterns. Together, Dave and Austin explore how metrics can empower individuals to take ownership of their health, the tension between conventional guidelines and personal experimentation, and what the future of open-source health data could look like.🔥 This episode is sponsored by us -- Own Your Labs 👉 https://ownyourlabs.com/tfp/11 Private blood testing services🩸Over 300 blood tests💰Extremely affordable❤️ We love our customers🔗 CONNECT WITH DAVE FELDMAN PROTOCOLMain Channel: https://youtube.com/@realDaveFeldmanX/Twitter: https://x.com/realDaveFeldmanInstagram: https://instagram.com/realDaveFeldmanWebsite: https://thefeldmanprotocol.com⏱ Chapters 0:00 – Introduction & Setting the Stage5:45 – Opening Reflections on Austin’s Energy and Setting10:30 – Early Experiences That Sparked Curiosity15:15 – First Encounters with Data, Health, and Experimentation20:00 – The Origins of a Systems Approach to Nutrition25:00 – Breaking Down the Lipid Energy Model Concept30:15 – What Early Self-Experiments Revealed35:20 – Exploring LDL and APOB from a New Perspective40:10 – Why Traditional Cholesterol Framing Falls Short45:00 – Digging Into Lipoprotein Transport Mechanisms50:05 – Triglycerides, Remnants, and Particle Flow55:15 – When Energy Demand Shapes Lipid Behavior1:00:10 – The Lean Mass Hyper-Responder Pattern1:05:00 – Genetics, Metabolism, and Individual Variation1:10:30 – LPL and LDL Receptor Pathways in Context1:15:20 – Familial Hypercholesterolemia and Diverse Risk Profiles1:20:15 – How Population Data Can Mislead Individual Cases1:25:10 – Mendelian Randomization and Its Hidden Assumptions1:30:00 – Study Design: What We Miss When We Aggregate1:35:00 – The Duration vs. Magnitude of LDL Exposure1:40:10 – Interpreting Meta-Analyses with Caution1:45:15 – Revisiting the PESA Trial and Imaging Insights1:50:05 – Understanding the “Three-Line Graph” Debate1:55:00 – Statistical Power, Noise, and Over-Interpretation2:00:10 – Regression Models and Data-Slicing Pitfalls2:05:20 – Plaque Progression and Clinical Translation2:10:00 – PCSK9 Insights and Unexpected Outcomes2:15:00 – Beyond LDL: Inflammation and Contextual Risk2:20:05 – Revisiting the Bradford Hill Criteria for Causality2:25:10 – Consistency, Dose Response, and Biological Plausibility2:30:00 – The Changing Landscape of Trial Reporting2:35:05 – How 2004 Altered Medical Transparency Rules2:40:00 – Scientific Discourse, Debate, and Misinterpretation2:45:15 – The Role of Skepticism in Evidence Review2:50:10 – The Value of Epistemic Humility in Science2:55:00 – Open Data, Collaboration, and Collective Learning3:00:10 – Case Studies and Self-Experimentation Insights3:05:00 – Reflections on N=1 Studies and Public Data Sharing3:15:00 – Designing Smarter Studies for the Future3:20:05 – Lessons Learned from Real-World Observation3:25:00 – Future of Lipid Research and Citizen Science3:30:00 – Revisiting Key Misconceptions About Cholesterol3:35:10 – Bridging Gaps Between Clinicians and Researchers3:40:00 – Empowering Individuals Through Accessible Data3:50:00 – Community, Collaboration, and Scientific Openness3:55:10 – Final Thoughts on Evidence, Curiosity, and Persistence4:00:00 – Closing Reflections & Gratitude#FeldmanProtocol #LDL #HDL #Cholesterol #ASCVD #ContinuousGlucoseMonitoring #CGM #MetabolicHealth #DataDrivenHealth #CitizenScience #OwnYourLabs #QuantifiedSelf #HealthData #PerformanceOptimization #DaveFeldman #HumanPerformance #MetabolicFlexibility #OpenSourceScience
In this episode, Dave sits down with Peter Ballerstedt, a retired forage agronomist and ruminant nutritionist known as "Don Pedro the Sod Father of the Ruminati," who brings a unique agricultural perspective to metabolic health discussions. Ballerstedt shares his 2007 transformation after reading Gary Taubes' book and how it led him to bridge agricultural science with the low-carb community. The conversation examines environmental arguments around animal agriculture, presents data on greenhouse gas emissions (12% animal vs 10% plant agriculture), explores the limitations of converting grassland to cropland, discusses the evolution of dietary guidelines since the 1970s, and examines Ballerstedt's concept of a "ruminant revolution" to address both human malnutrition and environmental concerns.🔥 This episode is sponsored by us -- Own Your Labs 👉 https://ownyourlabs.com/tfp/10 Private blood testing services🩸Over 300 blood tests💰Extremely affordable❤️ We love our customers🔗 CONNECT WITH DAVE FELDMAN PROTOCOL:Main Channel: @realDaveFeldmanX/Twitter: x.com/realDaveFeldman Instagram: instagram.com/realDaveFeldmanWebsite: thefeldmanprotocol.com⏱ Chapters0:00 – Introduction1:05 – Who is Peter Ballerstedt: The Sod Father of the Ruminati5:11 – Personal Journey: Pre-Diabetic to Low-Carb in 20076:16 – Gary Taubes' "Good Calories, Bad Calories"7:00 – First Low-Carb Conference10:34 – Lipophobia and the Anti-Red Meat Message11:23 – The 1977 Dietary Goals and McGovern Committee14:01 – Personal Transformation and Reversing Pre-Diabetes21:09 – Malnutrition vs. "Overnutrition"23:22 – Climate Change and Animal Agriculture24:14 – Greenhouse Gas Emissions: 22% Agriculture, 12% Animal29:06 – Land Use: Why We Can't Convert Grassland to Cropland30:31 – The Football Field Analogy: Class 1 Soils37:00 – Ruminants Converting Inedible Biomass to Human Food52:00 – Obesity Associated with Poverty1:07:00 – Animal Source Food and Economic Prosperity1:15:05 – The Grassroots Low-Carb Movement and 10% Tipping Point1:30:00 – Personal Stories: Reversing Diabetes Through Diet1:43:05 – Using AI and Large Language Models for Research1:52:11 – Obesity and Poverty: Gary Taubes' Key Insight1:55:42 – Ecosystem Services: Fire Management and Wildlife2:00:01 – Agricultural Biomass is Not Human Edible2:05:51 – Animal Source Food Demand by 20502:30:00 – Historical Medical Views on Meat3:01:14 – Malnutrition: 30-35 Million Deaths, $6.5 Trillion Cost3:02:03 – Red Meat and Cancer: Epidemiological Evidence3:04:40 – Hyperinsulinemia and Insulin Resistance3:07:53 – The Ruminant Revolution: Energy Transition Fund Redirection3:12:55 – Personal Story: A1C Over 11 to Diabetes Removed3:15:35 – The 10% Rule and Paradigm Shifts3:41:00 – Grass-Fed vs. Grain-Fed Beef3:42:20 – Avoiding Unnecessary Barriers to Adoption3:45:05 – The Greenland Paradox3:51:23 – Animal Rights vs. Animal Welfare3:53:23 – Separating Suffering from Mortality4:00:00 – Where to Find Peter#FeldmanProtocol #PeterBallerstedt #AnimalAgriculture #RegenerativeAgriculture #RuminantNutrition #LowCarb #KetoMedicine #Agronomy #ClimateChange #SustainableAgriculture #GrasslandEcosystems #MetabolicHealth #AnimalWelfare #GaryTaubes #DietaryGuidelines #FoodSystems #Malnutrition #SoilHealth #GrassFed #DaveFeldman
In this episode, Dave sits down with Dr. Eric Westman, associate professor of medicine at Duke University and founder of the Keto Medicine Clinic, who has built his practice around using dietary interventions to treat patients. Dr. Westman discusses his path from traditional internal medicine to researching low-carb approaches, including his early observations of patients whose cholesterol profiles improved on high-fat diets and his collaboration with Dr. Atkins in the late 1990s to conduct some of the first clinical studies on the Atkins diet. The conversation covers the current medical environment where GLP-1 drugs like Ozempic have become prominent weight loss treatments, the historical use of low-carb medicine dating back over a century, and Dr. Westman's perspective on why nutrition education has become less emphasized in medical training. From his YouTube channel that reaches millions of viewers monthly to his clinical work helping patients reverse diabetes through dietary changes, Dr. Westman shares his experience at the intersection of medical research, clinical practice, and the evolving approaches to treating metabolic conditions.🔥 This episode is sponsored by us -- Own Your Labs 👉 https://ownyourlabs.com/tfp/9 Private blood testing services🩸Over 300 blood tests💰Extremely affordable❤️ We love our customers🔗 CONNECT WITH DAVE FELDMAN PROTOCOL:Main Channel: @realDaveFeldmanX/Twitter: x.com/realDaveFeldman Instagram: instagram.com/realDaveFeldmanWebsite: thefeldmanprotocol.com⏱ Key Chapters0:00 – Introduction & Opening Thoughts1:04 – Who is Dr. Eric Westman & the Keto Medicine Clinic7:06 – Dr. Westman as the Original Keto Pioneer9:02 – The First Atkins Diet Patients: Unexpected Results12:17 – The 2004 Studies & Dr. Atkins' Tragic Death15:16 – Duke's Historical Connection to Dietary Medicine25:15 – GLP-1 Drugs vs. Dietary Interventions: The Current Divide32:20 – The Muscle Loss Problem with Weight Loss Drugs38:15 – The American Diabetes Association's Forgotten Origins47:10 – Addiction Models: Food vs. Tobacco & Alcohol1:05:15 – Glucose Metabolism & Keto Adaptation in Long-Term Practitioners1:15:00 – Animal Models vs. Human Studies: The Research Problem1:25:00 – Metabolic Status Impact on Lipid Profiles1:30:00 – Lean Mass Hyper-Responder Study Results & Heterogeneity1:40:00 – Brown & Goldstein's Work & Homozygous FH Cases1:55:00 – The Cholesterol Code Documentary Journey2:00:00 – Citizen Science Foundation & Crowdfunded Research2:10:00 – Heart Failure, Ketones & SGLT2 Inhibitors2:20:00 – Serial Killers Films & Athletic Performance on Keto2:35:00 – Eric's Bookshelf: Essential Low-Carb Literature2:45:00 – Hospital Food Systems & Institutional Change2:55:00 – Drug Development vs. Dietary Solutions3:00:00 – Polypharmacy & Deprescribing in Clinical Practice3:15:00 – Adapt Your Life Academy & Online Education3:30:00 – The Feldman Protocol & Cholesterol Manipulation3:45:00 – Closing Thoughts & Where to Find Dr. Westman#FeldmanProtocol #EricWestman #KetoMedicine #DietaryIntervention #AtkinsDiet #Duke #MedicalResearch #GLP1 #Ozempic #DiabetesReversal #LowCarb #FoodAsMedicine #CholesterolResearch #DaveFeldman #MedicalHistory
Can we really justify what we eat today by pointing to what our ancestors ate thousands of years ago? In this thought-provoking episode, I sit down with Alex Leaf, a scientific communicator and longtime researcher with Examine.com, to challenge some of the most persistent ideas in nutrition.We dive deep into the ancestral argument, the role of mTOR and protein in longevity, and the personal fat threshold hypothesis that could redefine how we view metabolic health and type 2 diabetes. From wrestling-induced bulimia to modern agriculture’s double-edged legacy, Alex brings a refreshingly perspective to some of the most polarizing conversations in nutrition.🔗 🔥 This episode is sponsored by us -- Own Your Labs 👉 https://ownyourlabs.com/tfp/8 Private blood testing services🩸Over 300 blood tests💰Extremely affordable❤️ We love our customersCONNECT WITH DAVE FELDMAN:Main Channel: YouTube.com/realDaveFeldmanX/Twitter: x.com/realDaveFeldman Instagram: instagram.com/realDaveFeldmanWebsite: thefeldmanprotocol.com⏱ Chapters1:07 – Who is Alex Leaf and how he started in nutrition3:59 – Wrestling, eating disorders & body image8:27 – Protein, mTOR & the longevity paradox11:15 – The importance of amino acid composition13:22 – Fasting, feeding cycles & “cell closing hours”15:46 – Do ancestral eating patterns actually make sense?18:00 – Food scarcity, evolution & modern adaptation20:10 – Agriculture: humanity’s double-edged sword22:45 – Are we engineering our own metabolic collapse?26:00 – Animal vs plant protein quality31:10 – Why “ancestral diet” arguments fall apart36:45 – Modern food, ultraprocessed diets & disease40:13 – The Standard American Diet as the control group44:04 – The personal fat threshold explained47:40 – How body fat triggers insulin resistance52:10 – Can weight loss reverse type 2 diabetes?58:30 – Does fasting insulin predict fat loss?1:03:00 – Linking triglycerides, HDL & metabolic health1:05:45 – ApoB, risk factors & what studies miss1:12:10 – The limits of adjustment in nutrition science1:17:30 – What makes lean mass hyper-responders unique
In this episode of The Feldman Protocol, Dave Feldman sits down with Nicholas Verhoeven PhD, the creator of @Physionic and recent molecular medicine graduate who has successfully transitioned from traditional academia to independent science communication. The conversation explores Nic's unique approach to content creation, including his decision to reject thousands of sponsorship offers to maintain editorial independence while building a sustainable business model. Dave and Nic dive deep into the methodology and findings of Dave's groundbreaking longitudinal keto study, examining how 100 lean mass hyperresponders with an average LDL of 272 mg/dL compared to matched controls from the Miami Heart study with an average LDL of 123 mg/dL. The discussion reveals fascinating insights about plaque progression, the challenges of proving causation in nutrition science, and the problematic certainty often displayed in epidemiological research. They tackle the nuanced differences between correlation and causation, critique the WHO's red meat classification, and explore why the nutrition field tends toward binary thinking rather than acknowledging the spectrum of evidence strength that should inform our understanding of health risks.🔥 This episode is sponsored by us -- Own Your Labs 👉 https://ownyourlabs.com/tfp/7 Private blood testing services🩸Over 300 blood tests💰Extremely affordable❤️ We love our customers🔗 CONNECT WITH DAVE FELDMAN:Main Channel: youtube.com/realDaveFeldmanX/Twitter: x.com/realDaveFeldmanInstagram: instagram.com/realDaveFeldmanWebsite: thefeldmanprotocol.com#NicVerhoeven #Physionic #KetoStudy #LeanMassHyperresponder #LDL #CardiovascularHealth #PlaqueProgression #ScienceCommunication #IndependentResearch #NutritionScience #EpidemiologyDebate #CausationVsCorrelation #RedMeatDebate #WHO #BradfordHillCriteria #ContentCreation #PhD #MolecularMedicine #HealthPodcast
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