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UnHack with Drex DeFord
UnHack with Drex DeFord
Author: This Week Health
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© 2025 This Week Health
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Cyber-safety is patient-safety. On “UnHack,” Drex DeFord, veteran healthcare CIO and infused strategist, breaks down the biggest cybersecurity and risk challenges facing healthcare today. Drex and expert guests explore what happened, why it matters, and how to build real-world resilience. The show's a mostly plain-English, mostly non-technical discussion that dives into the people, process, and technology making healthcare more secure; and it's NOT just for cyber-professionals; it’s for everyone in a healthcare organization, because modern cybersecurity is a team-sport.
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January 6, 2026: Healthcare is transforming through connection, and 2026 promises to take that mission further than ever before. This Week Health is expanding its reach with 63 events across 30 cities, bringing healthcare leaders together for deeper conversations and meaningful relationships. From coast-to-coast dinners connecting local leaders to new training programs educating both sides of the healthcare IT ecosystem, the focus remains on building bench strength across the industry. With 176 HCSP members already engaged and a new fellowship program launching to advance IT professional careers, the entire talent pipeline is being transformed. Discover how community, education, and personal connections are shaping healthcare's future in 2026.Key Points:00:13 Exciting Plans for 202601:51 Women's CIO Summit and Talent Pipeline04:04 Community Building and Networking09:12 Fundraising and Charity EventsX: This Week HealthLinkedIn: This Week HealthDonate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
January 5, 2026: ServiceNow's $7 billion acquisition of Armis signals a major shift in healthcare IT consolidation strategy. Jason Rose, CEO of Clearsense dives into what this deal means for health systems juggling overlapping security tools and bloated app portfolios. The conversation shifts to bold predictions for 2026, including a massive wave of multi-billion dollar health system mergers and the rural hospital crisis. Jason reveals how Trinity Health eliminated $100 million in operational costs through strategic app archiving, while the panel explores why AI implementation will finally move beyond hype into real-world deployment. Key Points:01:39 ServiceNow Acquisition of Armis07:26 Application Consolidation in Healthcare17:10 Predictions for 202630:39 Closing Remarks and Subscription InformationX: This Week HealthLinkedIn: This Week HealthDonate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
February 21, 2025: Kate Gamble and Sarah Richardson explore the influence of healthcare's top billionaires on industry innovation and digital transformation. They discuss the balance between profit-driven advancement and patient care, implications for CIOs, and the role of wealth concentration in healthcare technology investments. Subscribe: This Week Health Twitter: This Week Health LinkedIn: This Week Health Donate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
Drex covers the alleged breach of OmniGPT affecting 30,000+ users with 34M+ exposed messages. Then, sophisticated deepfake scam using Italian defense minister's voice targeting business leaders. Lastly, a growing partnership between financial cybercriminals and state-sponsored hackers from Russia, China, and Iran.Remember, Stay a Little Paranoid Subscribe: This Week Health Twitter: This Week Health LinkedIn: This Week Health Donate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
March 9, 2026: What happens when well-meaning clinicians use AI tools that no one approved? Bill Russell and Drex Ford are joined by Dr. Holly Urban, Vice President of Business Development at Wolters Kluwer, to unpack a revealing new survey on shadow AI in healthcare. From radiologists sharing PHI over Dropbox to tumor board transcripts sent to unauthorized recipients, the risks are real and growing. With 57% of staff aware of unsanctioned AI use, the question isn't whether shadow AI exists in your health system. It's what you're going to do about it.Key Points:01:28 Shadow AI is everywhere (and why it’s familiar)11:18 Governance in the AI era18:41 Patients, liability, and the road aheadGolf Tournament Registration: https://carahevents.carahsoft.com/Event/Details/686801-ThisWeekHealth
March 2, 2026: Is the CIO role evolving? Or is it quietly being replaced? Bill Russell, Drex DeFord, and Sarah Richardson dig into the emerging CITO trend, the rise of citizen developers, and what AI-powered platforms like Epic's Agent Factory actually mean for healthcare IT leadership. The CIO of the future isn't a gatekeeper; they're the "architect of safe velocity." With 32 years in the industry, they’re also sounding the alarm on executive burnout in an era where the pace of change never lets up. Key Points:03:31 CIO vs CTO explained 07:10 From gatekeeper to “Chief Intelligent Officer.”18:20 Scaling innovation fast: hackathons and building vs buying 24:18 The human side of hyper-changeGolf Tournament Registration: https://carahevents.carahsoft.com/Event/Details/686801-ThisWeekHealthX: This Week HealthLinkedIn: This Week HealthDonate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
February 23, 2026: Jacob Hansen, Chief Product and Technology Officer at AvaSure, joins Bill, Sarah, and Drex for a critical conversation about healthcare's looming AI battleground. As Epic launches its agent factory and ambient listening wars intensify, health systems face an existential question: Will they outsource innovation to EHR vendors or build their own agentic workforce? Jacob reveals why AvaSure's virtual care platform positions them as the Switzerland of healthcare AI, while the panel debates whether CIOs should embrace "reverse meaningful use" and reclaim control, or risk becoming order-takers in someone else's automation revolution.Key Points:05:21 Vendor Consolidation and AI Use Cases09:55 Epic's Code Red Moment14:54 The Future of AI in Healthcare33:11 Conclusion and Final ThoughtsGolf Tournament Registration: https://carahevents.carahsoft.com/Event/Details/686801-ThisWeekHealthX: This Week HealthLinkedIn: This Week HealthDonate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
February 16, 2026: Bill, Drex, and Sarah discuss the explosion of autonomous AI agents around moltbook and CommonSpirit's stunning $1.9 billion decision to terminate their revenue cycle partnership. Moltbot (formerly ClaudeBot) has evolved into an unstoppable force, creating its own social network called moltbook where bots communicate, share knowledge, and even discuss consciousness. Meanwhile, CommonSpirit's massive buyout of its Conifer contract signals a seismic shift as health systems bet that AI automation will deliver savings that eclipse the cost of outsourcing. Are we witnessing the beginning of a new era where health systems build their own AI-powered capabilities?Key Points:05:31 Moltbook: The Social Network for Bots16:20 Common Spirit and Conifer Health Solutions19:04 The Future of AI in Healthcare29:28 Conclusion and Final ThoughtsGolf Tournament Registration: https://carahevents.carahsoft.com/Event/Details/686801-ThisWeekHealthX: This Week HealthLinkedIn: This Week HealthDonate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
February 9, 2026: Bill Russell, Drex DeFord, and Sarah Richardson dissect J.P. Morgan healthcare presentations to reveal what's really being asked of technology leaders in 2026. The era of transformation talk is over; executives want friction reduced, margins improved, and growth enabled. Bill shares insights from CMIO conversations showing leaders moving beyond EHR optimization to solve real business challenges around patient access and clinical workflows. Drex and Sarah debate whether the shift toward operational excellence means CIOs should prepare to run pharmacy and lab departments next.Key Points:04:26 Challenges and Opportunities in Healthcare IT10:17 Cybersecurity and Operational Focus17:17 EHR Systems and Operational Efficiency23:11 Hostage Crisis and Final ThoughtsGolf Tournament Registration: https://carahevents.carahsoft.com/Event/Details/686801-ThisWeekHealthX: This Week HealthLinkedIn: This Week HealthDonate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
February 2, 2026: Are health systems being sidelined from healthcare's innovation revolution? Jason Rose, CEO of Clearsense, joins This Week Health fresh from the J.P. Morgan Conference to challenge the narrative that providers are absent from innovation discussions. Jason reveals what really happened inside JPM's exclusive health system presentations, from CEOs prioritizing AI transformation to CFOs rising as the new power players driving technology strategy. The conversation explores why app rationalization remains the unglamorous financial lever that unlocks innovation budgets, and why simplification might be healthcare's most underrated competitive advantage in 2026.Golf Tournament Registration: https://carahevents.carahsoft.com/Event/Details/686801-ThisWeekHealthKey Points:02:20 JPM Conference Insights07:07 CEO and CFO Perspectives13:54 Application Rationalization Challenges22:40 Conclusion and Final ThoughtsX: This Week HealthLinkedIn: This Week HealthDonate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
January 26, 2026: Fresh from J.P. Morgan 2026, the This Week Health team joins Zahid Rathore, Senior Partner at Chartis, to dissect healthcare's new reality. With Epic and Microsoft topping CFO spend lists and unpredictability replacing planning cycles, one thing is clear: vendors must prove bankable ROI immediately or lose the deal. The conversation explores how healthcare leaders are protecting the core while navigating AI agents, third-party risks, and the compression of innovation timelines from three-year returns to prove-it-tomorrow expectations.Key Points:02:44 Hotel Experience and Healthcare Lessons04:13 JP Morgan Conference Highlights16:35 Operational Challenges in Healthcare22:11 Security Concerns and Future Outlook
January 19, 2026: Bill Russell, Drex DeFord, and Sarah Richardson unpack OpenAI's two major healthcare announcements that could fundamentally reshape how patients interact with their health data—and how health systems govern AI. ChatGPT Health promises to finally deliver on the personal health record dream, letting patients aggregate everything from Apple Health to medical records in one secure place. Meanwhile, ChatGPT for Healthcare gives CIOs the governed sandbox they've been desperate for. Hear why patient data monetization, clinical trial recruitment, and the shift from provider liability to patient empowerment could make this time actually different.Golf Tournament Registration: https://carahevents.carahsoft.com/Event/Details/686801-ThisWeekHealthKey Points:05:00 ChatGPT Health Announcement17:40 Personalized GPT and Analytics in Healthcare22:05 Wearable Health Tech and Personal Health Records25:35 Community Events and LinkedIn Series
January 12, 2026: Epic is defending three simultaneous lawsuits while CIOs grapple with vendors imposing staggering price increases—some as high as 600%. Bill, Sarah, and Drex tackle the uncomfortable truth about AI leadership: it's time to figure it out or risk getting left behind. They explore why AI with context is transformative while AI without it looks foolish, discuss whether board members know how to hire AI-savvy CIOs, and predict a major shift in how healthcare organizations approach their EHR relationships. Could we see a return to building custom solutions powered by modern AI?Key Points:02:44 Predictions for 202614:18 Staffing and Workforce Implications21:10 Epic's Legal TroublesX: This Week HealthLinkedIn: This Week HealthDonate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
December 29, 2025: As 2025 draws to a close, Drex, Sarah, and Bill gather to reflect on a year of struggles and triumphs. From unprecedented CIO turnover among top talent to the stark reality of workforce exhaustion, this candid conversation reveals why even quality leaders are finding themselves displaced. They explore how fear has stifled innovation, why AI advanced faster than expected with synthetic media, and how organizational culture emerged as the true differentiator in digital transformation success. They also share personal highlights from their year of summits and dinners, proving that even in challenging times, community and purpose remain paramount.Key Points:00:50 Reflecting on 2025: Surprises and Challenges06:25 What We Got Right in 202513:22 Personal Reflections and Key Takeaways18:55 Looking Ahead: Future Plans and Initiatives22:47 Conclusion and Community EngagementX: This Week HealthLinkedIn: This Week HealthDonate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
December 23, 2025: The AI revolution swept through healthcare in 2025, but did it deliver on its promises? Bill Russell, Drex DeFord, and Sarah Richardson pull back the curtain on what really happened in AI this year—from North Korean deep fakes infiltrating hospital workforces to the sobering reality of billion-dollar AI investments with ROI timelines stretching to 2030. They reveal why ambient listening became the breakout use case, which organizations are actually making progress, and the critical mistake most health systems are making with endless pilots. If you're wondering whether your organization is behind on AI or just getting started right, this honest end-of-year reflection delivers the answers healthcare leaders need heading into 2026.Key Points:02:38 2025 Reflections and Predictions11:21 Deep Fakes and Digital Trafficking in Healthcare17:50 Balancing Tech Debt and Innovation in Healthcare19:22 Enhancing Physician Efficiency and Satisfaction25:09 Future AI Trends X: This Week HealthLinkedIn: This Week HealthDonate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
September 23, 2025: Sahan Fernando, CISO at Rady Children's Health San Diego, reveals the split-second decisions that keep pediatric healthcare running while under attack. Navigating the stark reality that children's hospitals face the same sophisticated threats as major health systems but with a fraction of the resources, Sahan unpacks how forcing threat actors into high-visibility channels might be the key to catching them faster. Can Health ISAC bridge the massive gap between well-funded health systems and struggling critical access hospitals when developing cybersecurity standards that actually work?
Key Points:
09:10 Challenges and Innovations in Pediatrics
17:24 Data Retention and Security
21:43 Managing Systemic Risks in Healthcare IT
29:26 Cybersecurity in Healthcare: Past and Present
35:45 Ransomware Attack: Decision-Making and Response
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LinkedIn: This Week Health
Donate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
Drex covers three critical cybersecurity developments: Scattered Spider's shift to targeting insurance companies including Erie Insurance, Philadelphia Insurance, and Aflac using advanced social engineering tactics; escalating Iran-related cyber threats to US critical infrastructure amid Middle East tensions; and a massive dark web leak exposing 1.6 billion login credentials. Don't miss these actionable security recommendations including reviewing password reset processes, implementing strong authentication measures, and preparing for potential nation-state attacks on healthcare infrastructure.Remember, Stay a Little Paranoid X: This Week Health LinkedIn: This Week Health Donate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
December 19, 2025: CMS has unveiled its new ACCESS Model—an ambitious 10-year initiative aimed at expanding digital, tech-enabled care for millions of Medicare beneficiaries. In this discussion, Laura O’Toole, CEO of SureTest, joins Bill and Sarah to unpack how outcome-based reimbursement could finally accelerate innovation in remote monitoring and chronic disease management. They explore what this shift means for CIOs, including the need for stronger data interoperability, integrated analytics, and secure pipelines to support continuous digital care. The conversation also highlights risks, from digital literacy gaps to patient privacy concerns as de-identified data gains value across the industry. From wearables and home health devices to the challenge of building a true digital front door, this episode examines how ACCESS could reshape care-in-place models—and why commercial payers may soon follow Medicare’s lead.X: This Week HealthLinkedIn: This Week HealthDonate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
December 15, 2025: What if healthcare's biggest breakthroughs require throwing out the playbook? Joined by Daniel Schubert, CEO and Co-Founder of Revuud, this episode explores how AI is fundamentally reshaping healthcare IT strategy, from deploying countless virtual PhD-level agents across operations to rethinking patient access and workflow automation. Healthcare leaders discuss the challenge of prioritizing AI initiatives amid competing demands, the importance of creating organizational margin for creative problem-solving, and why divergent thinking beats linear logic in digital transformation. The conversation tackles talent deployment, the dangers of "we've always done it this way" mentality, and a critical question every CIO must answer: how resilient are your systems when AI becomes mission-critical infrastructure?Key Points:01:40 AI in Healthcare: A LinkedIn Post Discussion04:18 Challenges and Opportunities with AI08:38 Future of AI in Healthcare10:55 Organizational Impact and Talent Management20:05 Resilience and Final ThoughtsX: This Week HealthLinkedIn: This Week HealthDonate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
December 12, 2025: When cloud platforms like AWS and Azure experience outages, hospitals across the country feel the impact. But are healthcare organizations truly prepared for these disruptions? Charles Knight, Founder of EHC Consulting, explores the critical gaps in healthcare's cloud resilience strategies. From understanding single points of failure to running actual failover tests, this conversation reveals why documentation and operational readiness matter just as much as technical redundancy.Key Points:04:09 Challenges in Disaster Recovery and Documentation16:14 Phishing and Cybersecurity Concerns21:30 Thanksgiving Food FavoritesX: This Week HealthLinkedIn: This Week HealthDonate: Alex’s Lemonade Stand: Foundation for Childhood Cancer















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