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© 2025 Healthcare Unfiltered
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Healthcare Unfiltered is an honest, raw, timely podcast tackling any and all topics in healthcare that affect stakeholders. Dr. Chadi Nabhan uses his dynamic conversational skills to challenge his guests to address controversial and important topics. He also brings on world renowned experts to discuss clinical advances in medicine.
254 Episodes
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Gavin MacBeath, CEO of TScan Therapeutics, takes us inside his journey from scientist to biotech leader and what it means to build and run a therapeutic development company at the cutting edge of immuno-oncology. He breaks down how TScan’s platform works to discover and match T-cell receptors (TCRs) with their antigens, and why TCR-T therapies may provide distinct benefits over CAR-T approaches, especially when tackling solid tumors. He also discusses which diseases are most likely to respond...
Dr. Sameer Keole, radiation oncologist at Mayo Clinic Arizona and president of ASTRO, joins the show to preview the upcoming ASTRO Annual Meeting and its key themes. He reflects on his presidential term, discussing accomplishments, lessons learned, and initiatives like his “defense to offense” vision and community outreach efforts. Dr. Keole also tackles hot-button topics in radiation oncology, including the evolving roles of proton therapy and artificial intelligence in patient care. Check o...
Dr. Mark Lewis visits Healthcare Unfiltered Express to provide how data presented at major scientific meetings, such as ASCO, needs to be put in context from a patient perspective.
In this follow-up episode, Dr. Ed Livingston—renowned surgeon, educator, researcher, and former deputy editor at JAMA—returns to discuss the latest developments in his ongoing legal battle. He reflects on what has transpired in the three months since his last appearance, offering insights into the discovery process and the legal details shaping the case as it heads toward a July 2026 trial date.Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. www.chadinabhan...
Dr. Halmos from Montefiore in New York shares his views on the most impactful practice changing or informing data for lung cancer from the ASCO 2025 meeting.
Dr. Douglas Flora, Executive Medical Director of Oncology Services at St. Elizabeth Healthcare Cancer Center and Editor-in-Chief of the journal AI in Precision Oncology, shares his pragmatic perspective on how AI is reshaping cancer care today and tomorrow. He discusses real-world applications such as FDA-approved pattern recognition tools in imaging and pathology, how AI may soon integrate with ctDNA to guide treatment decisions, and the clinical trials needed to advance this field. Dr. Flor...
Dr. Rajkumar from the Mayo Clinic explains why many have been disappointed by the ODAC decision to recommend not approving Benrep for relapsed/refractory multiple myeloma. Thought provoking. This was taped live while we broadcasted on Twitter Spaces on 7/22/2025.
Dr. Saurabh Dahiya from Stanford University explains the recent changes in the FDA recommendations regarding the monitoring program previously mandated for centers delivering CAR-T therapies, and why this decision was celebrated by patients and their physicians.
Dr. Jasmine Kamboj shares her wisdom and advice on starting fellows on how to survive and thrive in fellowship. A MUST listen.
Dr. Virginia Kaklamani, world renowned breast cancer specialist and researcher, visits with Healthcare Unfiltered EXPRESS to detail how this class of agents are used in metastatic and early stage breast cancer. A perfect guide for all clinicians.
At the latest ASCO-2025 meeting, Dr. Chris Booth shared the results of a study showing that adjuvant structured exercise improves overall survival in colon cancer. He joins Healthcare Unfiltered EXPRESS to detail the study, its findings, and what is next. Please share and join the conversation.
Dr. Monique Diaz, Chief Medical Informatics Officer at CommonSpirit Health, unpacks the intersection of big data, clinical care, and healthcare innovation. She shares how informatics transforms resource allocation, patient engagement, and system efficiency—while offering a behind-the-scenes look at the daily responsibilities of a CMIO, from EMR coding to AI integration. Dr. Diaz also explores the evolving relationship between informatics and AI, and how future advancements hinge on ethical fr...
Dr. Sandy Scheinbaum, founder of the Functional Medicine Coaching Academy, joins the show to break down the principles of functional medicine—a patient-centered approach that integrates lifestyle, nutrition, psychology, and mind-body practices to address the root causes of illness. She shares how her academy trains coaches to guide individuals through sustainable behavior change, explains how mental and emotional states can directly impact physical symptoms, and discusses why functional medic...
Dr. Anthony DiGiorgio, a neurosurgeon at UCSF with a strong interest in healthcare policy, joins the show to unpack the complex and often misunderstood world of Medicaid. In a wide-ranging and nuanced discussion, he explores who qualifies for coverage, why most Medicaid spending goes to groups people don’t typically expect, and whether the system should be expanded or fundamentally reformed. Dr. DiGiorgio outlines his support for a robust safety net, emphasizing targeted subsidies over a gove...
Dr. Ed Livingston, renowned surgeon, educator, and researcher, who was a former deputy editor at JAMA, found himself out of a job after a JAMA podcast he hosted with Dr. Mitch Katz that discussed, among other items, structural racism as a contributor to the high mortality in minorities from COVID. This incident led to a series of lawsuits, some of which were highly publicized.Ed shares behind the scenes events, incidents, and what transpired in 2021, and how the AMA handled the situation. In ...
Ben Casavant, co-founder and CEO of Tasso, joins the show to discuss how he transformed the idea of patient-led blood collection into a reality through devices like Tasso+. He explains how Tasso’s self-collection kits—designed to be easy, virtually painless, and used anytime at home—solve the scalability issues of mobile phlebotomy while improving patient convenience, adherence, and access to care. Casavant also details the company’s growth journey, its FDA-cleared and CE-marked products, the...
Dr. Pallawi Torka of Memorial Sloan Kettering Cancer Center joins to share highlights from ASCO and EHA 2025 on the evolving landscape of B-cell lymphomas, including Hodgkin lymphoma, diffuse large B-cell lymphoma (DLBCL), and follicular lymphoma. She offers in-depth insights on the STARGLO study and its recent ODAC review, the POLARGO trial, a rare T-cell leukemia (T-LGL) study, and new data supporting nivolumab-AVD in frontline Hodgkin lymphoma. Additional discussion includes the inMIND tri...
Dr. Ben Derman of the University of Chicago Medicine joins the show to unpack major updates in multiple myeloma presented at ASCO and EHA 2025. He discusses the growing role of quadruple therapy across all patient populations and its implications for the future of autologous stem cell transplant, including insights from the MIDAS trial on MRD-guided transplant decisions. Additional highlights include MRD-negativity as a potential off-ramp for maintenance therapy, evolving data from frontline ...
Joe DePinto, MBA, Head of Cell, Gene & Advanced Therapies at McKesson, joins the show to discuss InspiroGene, McKesson’s end-to-end platform built to address the complex delivery, coordination, and commercialization needs of cell and gene therapies. He breaks down how InspiroGene integrates logistics, specialty pharmacy, patient support services, and real-time data tracking to close critical gaps in the CGT ecosystem—especially around why many eligible patients are still not being identif...
Chadi sits down with Lou Weisbach, entrepreneur and founder of the American Center for Cures, who shares his ambitious mission to raise $750 billion through an innovative public-private bond model to accelerate the prevention and cure of chronic diseases like cancer, Alzheimer's, diabetes, and Parkinson’s. Weisbach discusses how his model is designed to align incentives across government, industry, and research institutions, bridging political divides and pharmaceutical interests to focus on ...
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