The European Molecular Biology Laboratory (EMBL) Alumni Chats Series

George Simos (EMBL Postdoctoral Fellow 1990-95) chats with Thomas Vaccari (EMBL Predoctoral Fellow 1999-2004). George reflects on his first impressions upon joining EMBL in the early 90s, his return to Greece and efforts to bring back some of the culture and approach to research that he experienced in Heidelberg. He also explains his work on hypoxia and the thrill he gets when discovering something new in his research. This conversation was recorded in July 2025. Alumni Chat contributors are members of the European Molecular Biology Laboratory (EMBL) community. The opinions expressed are their own and are not necessarily representative of the views of EMBL or any other party. The mere appearance of content on EMBL Alumni accounts does not constitute an endorsement by EMBL. Production and Editing: EMBL Alumni Relations Content and Interviews: Angus Lamond and Thomas Vaccari Music: Eco Technology by Aleksey Chistilin from Pixabay Thanks to: EMBL Audiovisual and EMBL Design Sponsored by: EMBLEM © European Molecular Biology Laboratory (EMBL)

Thomas Graf (EMBL Head of Unit, 1983-1998) speaks with Angus Lamond (EMBL Group Leader, 1987-1995) about the potential of personalised cancer treatment, the role of basic research in the Covid-19 response and advice for young scientists. This interview was recorded in July 2022 Alumni Chat contributors are members of the European Molecular Biology Laboratory (EMBL) community. The opinions expressed are their own and are not necessarily representative of the views of EMBL or any other party. The mere appearance of content on EMBL Alumni media accounts does not constitute an endorsement by EMBL. Production and Editing: EMBL Alumni Relations Content and Interviews: Angus Lamond and Thomas Vaccari Music: Eco Technology by Aleksey Chistilin from Pixabay Thanks to: EMBL Audiovisual and EMBL Design Sponsored by: EMBLEM © European Molecular Biology Laboratory (EMBL)

In this interview, electron microscopy expert Erin Tranfield (EMBL Postdoc, 2009-2013) discusses her unconventional career path with Thomas Vaccari (EMBL Predoc 1999-2004) which led from researching air pollution's impact on the heart to studying lunar dust toxicology at NASA. She explains that electron microscopy is a powerful tool because it uses electrons instead of photons to achieve a higher resolution, allowing scientists to distinguish structures that are extremely close together. Beyond technical details, Erin highlights the breadth of biological research in space exploration, ranging from waste management to growing food in alien soil. She also stresses the importance of fine-tuning imaging techniques to match specific scientific questions rather than over-collecting unnecessary data. Finally, Erin shares her personal experience with a spinal cord injury, advocating for greater accessibility in the lab and the value of diverse perspectives in the scientific community. By being open about her disability, she aims to model a future where science is inclusive for individuals with various physical and learning differences.Alumni Chat contributors are members of the European Molecular Biology Laboratory (EMBL) community. The opinions expressed are their own and are not necessarily representative of the views of EMBL or any other party. The mere appearance of content on EMBL Alumni media channels does not constitute an endorsement by EMBL. Production and Editing: EMBL Alumni Relations Content and Interviews: Angus Lamond and Thomas Vaccari Music: Eco Technology by Aleksey Chistilin from Pixabay Thanks to: EMBL Audiovisual and EMBL Design Sponsored by: EMBLEM © European Molecular Biology Laboratory (EMBL)

Ilaria Piazza (EMBL Predoctoral Fellow, 2009-2014) speaks with Thomas Vaccari (EMBL Predoctoral fellow, 1999-2004) about her career progression to becoming a group leader, the value of working in different countries for scientific curiosity and winning the John Kendrew Award. This interview was conducted in July 2022.Alumni Chat contributors are members of the European Molecular Biology Laboratory (EMBL) community. The opinions expressed are their own and are not necessarily representative of the views of EMBL or any other party. The mere appearance of content on EMBL Alumni media channels does not constitute an endorsement by EMBL.Production and Editing: EMBL Alumni RelationsContent and Interviews: Angus Lamond and Thomas VaccariMusic: Eco Technology by Aleksey Chistilin from PixabayThanks to: EMBL Audiovisual and EMBL DesignSponsored by: EMBLEM© European Molecular Biology Laboratory (EMBL)

Denis Duboule (EMBL Group Leader 1988-1993) chats with Thomas Vaccari (EMBL Predoctoral Fellow 1999-2004). Denis reflects on his arrival as a group leader at EMBL in the 1980s, and on how EMBL’s freedom and international spirit helped shape his identity as a European scientist. He also shares memories of working for Director General Fotis Kafatos and his pride in giving the inaugural Kafatos Lecture. This conversation was recorded in September 2025. Alumni Chat contributors are members of the European Molecular Biology Laboratory (EMBL) community. The opinions expressed are their own and are not necessarily representative of the views of EMBL or any other party. The mere appearance of content on EMBL Alumni media channels does not constitute an endorsement by EMBL. Production and Editing: EMBL Alumni Relations Content and Interviews: Angus Lamond and Thomas Vaccari Music: Eco Technology by Aleksey Chistilin from Pixabay Thanks to: EMBL Audiovisual and EMBL Design Sponsored by: EMBLEM © European Molecular Biology Laboratory (EMBL)

Maria Tosches (EMBL Predoctoral Fellow, 2007-2014) speaks with Thomas Vaccari (EMBL Predoctoral fellow, 1999-2004) about her first experiences of 'Evo-Devo' at EMBL, the challenges of working on non-established models and studying the cerebral cortex of reptiles. This interview was recorded in July 2022. Maria was the recipient of the 2022 John Kendrew Award. You can watch her award presentation here - • Maria Tosches - 2022 John Kendrew Award Re... Alumni Chat contributors are members of the European Molecular Biology Laboratory (EMBL) community. The opinions expressed are their own and are not necessarily representative of the views of EMBL or any other party. The mere appearance of content on EMBL Alumni channels does not constitute an endorsement by EMBL. Production and Editing: EMBL Alumni Relations Content and Interviews: Angus Lamond and Thomas Vaccari Music: Eco Technology by Aleksey Chistilin from Pixabay Thanks to: EMBL Audiovisual and EMBL Design Sponsored by: EMBLEM © European Molecular Biology Laboratory (EMBL)

Claire O'Donovan (Team Leader Protein Function & Head of Metabolomics, EMBL-EBI, 1994-2024), a pioneer in computational biology, discusses her career at EMBL-EBI with Angus Lamond (EMBL Group Leader, 1987-1995). She explains the evolution of Swiss Prot, a protein database, and its global impact. Claire highlighted the importance of open access data and collaborations and stressed the need for continued investment in bioinformatics to support AI advancements. This conversation was recorded in July 2025. Alumni Chat contributors are members of the European Molecular Biology Laboratory (EMBL) community. The opinions expressed are their own and are not necessarily representative of the views of EMBL or any other party. The mere appearance of content on the EMBL Alumni RSS account does not constitute an endorsement by EMBL. Production and Editing: EMBL Alumni Relations Content and Interviews: Angus Lamond and Thomas Vaccari Music: Eco Technology by Aleksey Chistilin from Pixabay Thanks to: EMBL Audiovisual and EMBL Design Sponsored by: EMBLEM © European Molecular Biology Laboratory (EMBL)

Leo Burger (Head of Mechanical Workshop, EMBL Heidelberg, 1979-2023) speaks with Thomas Vaccari (Predoctoral fellow, EMBL Heidelberg, 1999-2004) and Angus Lamond (Group Leader, EMBL Heidelberg, 1987-1995). Leo reflects on over 40 years of building innovative and high quality equipment in the Mechanical Workshop at EMBL. This interview was conducted in March 2024. Alumni Chat contributors are members of the European Molecular Biology Laboratory (EMBL) community. The opinions expressed are their own and are not necessarily representative of the views of EMBL or any other party. The mere appearance of on EMBL Alumni media accounts does not constitute an endorsement by EMBL.Production and Editing: EMBL Alumni RelationsContent and Interviews: Angus Lamond and Thomas VaccariMusic: Eco Technology by Aleksey Chistilin from PixabayThanks to: EMBL Audiovisual and EMBL DesignSponsored by: EMBLEM© European Molecular Biology Laboratory (EMBL)

Sigrid Reinsch (Postdoctoral Fellow, EMBL Heidelberg, 1992-1998) discusses her career journey from EMBL to NASA with Angus Lamond (EMBL Group Leader, 1987-1995). She details the challenges of transitioning from EMBL and explains NASA's focus on human space exploration and understanding life in extreme environments. She also discusses NASA's education programs and the need for continued funding. This conversation was recorded in July 2025. Alumni Chat contributors are members of the European Molecular Biology Laboratory (EMBL) community. The opinions expressed are their own and are not necessarily representative of the views of EMBL or any other party. The mere appearance of content on the EMBL Alumni RSS account does not constitute an endorsement by EMBL. Production and Editing: EMBL Alumni Relations Content and Interviews: Angus Lamond and Thomas Vaccari Music: Eco Technology by Aleksey Chistilin from Pixabay Thanks to: EMBL Audiovisual and EMBL Design Sponsored by: EMBLEM © European Molecular Biology Laboratory (EMBL)

Wieland Huttner (Group Leader, EMBL Heidelberg, 1985-1990) speaks with Thomas Vaccari (EMBL Predoctoral Fellow, 1999-2004) about the establishment of EMBL's PhD programme and his co-founding of the Max Planck Institute in Dresden with other EMBL alumni. This interview was conducted in July 2024. Alumni Chat contributors are members of the European Molecular Biology Laboratory (EMBL) community. The opinions expressed are their own and are not necessarily representative of the views of EMBL or any other party. The mere appearance of content on EMBL Alumni media channels does not constitute an endorsement by EMBL. Production and Editing: EMBL Alumni Relations Content and Interviews: Angus Lamond and Thomas Vaccari Music: Eco Technology by Aleksey Chistilin from Pixabay Thanks to: EMBL Audiovisual and EMBL Design Sponsored by: EMBLEM © European Molecular Biology Laboratory (EMBL)

Eric Wieschaus (EMBL Group Leader 1978-81) chats with Thomas Vaccari (EMBL Predoctoral Fellow 1999-2004). Eric looks back on his groundbreaking work on Drosophila genetics with Christiane Nüsslein-Volhard at EMBL—research that led to the 1995 Nobel Prize in Physiology or Medicine. He also reflects on staying grounded amid recognition, his commitment to teaching, and what it means to “do science that works.” This conversation was recorded in September 2025.Alumni Chat contributors are members of the European Molecular Biology Laboratory (EMBL) community. The opinions expressed are their own and are not necessarily representative of the views of EMBL or any other party. The mere appearance of on EMBL Alumni media accounts does not constitute an endorsement by EMBL. Production and Editing: EMBL Alumni Relations Content and Interviews: Angus Lamond and Thomas Vaccari Music: Eco Technology by Aleksey Chistilin from Pixabay Thanks to: EMBL Audiovisual and EMBL Design Sponsored by: EMBLEM © European Molecular Biology Laboratory (EMBL)

Jacqueline Dreyer-Lamm (Head of External Scientific Courses, 2009-2018) chats with Thomas Vaccari (EMBL Predoctoral Fellow 1999-2004). Jacqueline discussed her role at EMBL, focusing on building and equipping labs, and developing new courses, as well as her efforts to support scientific research in underdeveloped countries through equipment transfers. Post-EMBL, she transitioned to a startup role, managing operations and grants for a drug development company.This conversation was recorded in July 2025.Alumni Chat contributors are members of the European Molecular Biology Laboratory (EMBL) community. The opinions expressed are their own and are not necessarily representative of the views of EMBL or any other party. The mere appearance of content on the EMBL Alumni RSS account does not constitute an endorsement by EMBL.Audio Production and Editing: EMBL Alumni RelationsContent and Interviews: Angus Lamond and Thomas VaccariMusic: Eco Technology by Aleksey Chistilin from PixabayThanks to: EMBL Audiovisual and EMBL DesignSponsored by: EMBLEM© European Molecular Biology Laboratory (EMBL)

Philip Avner (Head of EMBL Rome, 2012-2020) sets out his career trajectory in conversation with Angus Lamond (EMBL Group Leader, 1987-1995). From studying agricultural botany at the University of Newcastle to becoming head of EMBL Rome. He highlights his transition from biochemistry to genetics, influenced by mentors like Piotr Slonimsky and Francois Jacob. After a successful career in Paris, he joined EMBL Rome to foster better integration between EMBL and the Italian scientific community.This conversation was recorded in July 2024.Alumni Chat contributors are members of the European Molecular Biology Laboratory (EMBL) community. The opinions expressed are their own and are not necessarily representative of the views of EMBL or any other party. The mere appearance of content on the EMBL Alumni RSS account does not constitute an endorsement by EMBL.Production and Editing: EMBL Alumni RelationsContent and Interviews: Angus Lamond and Thomas VaccariMusic: Eco Technology by Aleksey Chistilin from PixabayThanks to: EMBL Audiovisual and EMBL DesignSponsored by: EMBLEM © European Molecular Biology Laboratory (EMBL)

Edith Heard (EMBL Director General 2019-2025) discusses her legacy at EMBL with Angus Lamond (EMBL Group Leader, 1987-1995). Edith emphasises the crucial role of unexpected results in advancing scientific discovery and innovation, encouraging researchers to embrace surprising findings, as they often spark new insights and breakthroughs. Edith also provides the context to EMBL embracing the research of planetary biology and EMBL's unique position to lead Europe’s exploration in collaborative science and AI. This conversation was recorded in July 2025. Alumni Chat contributors are members of the European Molecular Biology Laboratory (EMBL) community. The opinions expressed are their own and are not necessarily representative of the views of EMBL or any other party. The mere appearance of content on the EMBL Alumni RSS account does not constitute an endorsement by EMBL. Production and Editing: EMBL Alumni Relations Content and Interviews: Angus Lamond and Thomas Vaccari Music: Eco Technology by Aleksey Chistilin from Pixabay Thanks to: EMBL Audiovisual and EMBL Design Sponsored by: EMBLEM © European Molecular Biology Laboratory (EMBL)

Anne Ephrussi (EMBL Group Leader, Senior Scientist and Director for the EMBL International Centre for Advanced Training 1992-2023) chats with Thomas Vaccari (EMBL Predoctoral Fellow 1999-2004). Anne explains the background to starting her lab at EMBL in the early 90s and the questions she sought to investigate. She encourages young researchers to take risks and also reflects on the future of Oskar and RNA research. This conversation was recorded in September 2025.Alumni Chat contributors are members of the European Molecular Biology Laboratory (EMBL) community. The opinions expressed are their own and are not necessarily representative of the views of EMBL or any other party. The mere appearance of video content on the EMBL Alumni YouTube account does not constitute an endorsement by EMBL. Audio Production and Editing: EMBL Alumni Relations Content and Interviews: Angus Lamond and Thomas Vaccari Music: Eco Technology by Aleksey Chistilin from Pixabay Thanks to: EMBL Audiovisual and EMBL Design Sponsored by: EMBLEM © European Molecular Biology Laboratory (EMBL)

Rolf Apweiler (EMBL-EBI Director 1987-2025) speaks with Angus Lamond (EMBL Group Leader 1987-1995) about his start at EMBL as a student helper all the way to jointly leading the EBI. The huge growth of data in life sciences he witnessed and supported along the way and the importance of international collaboration, standardization, and cybersecurity. He reflects on the impact of AI on data curation and annotation, and discuss the Open Targets project, a public-private partnership to improve drug development through better genetic understanding.This conversation was recorded in July 2025.Alumni Chat contributors are members of the European Molecular Biology Laboratory (EMBL) community. The opinions expressed are their own and are not necessarily representative of the views of EMBL or any other party. The mere appearance of content on the EMBL Alumni RSS account does not constitute an endorsement by EMBL.Audio Production and Editing: EMBL Alumni RelationsContent and Interviews: Angus Lamond and Thomas VaccariMusic: Eco Technology by Aleksey Chistilin from PixabayThanks to: EMBL Audiovisual and EMBL DesignSponsored by: EMBLEM© European Molecular Biology Laboratory (EMBL)

Moritz Gerstung (EMBL-EBI Group Leader, 2015-2021) speaks with Angus Lamond (EMBL Group Leader, 1987-1995), discussing his transition from physics to computational biology, driven by the complexities of biological systems. He highlights his work at EMBL-EBI, which focused on cancer genomes and tumour dynamics using next-generation sequencing and AI tools. Moritz emphasised the importance of open data access, citing EMBL's role in storing and sharing genomes. He noted the significant impact of AI in cancer research, including the analysis of tumor microscopy and electronic health records. Moritz also discussed the challenges and potential of AI in healthcare, stressing the need for regulatory frameworks and critical assessment. This conversation was recorded in July 2025. Alumni Chat contributors are members of the European Molecular Biology Laboratory (EMBL) community. The opinions expressed are their own and are not necessarily representative of the views of EMBL or any other party. The mere appearance of video content on the EMBL Alumni RSS account does not constitute an endorsement by EMBL. Audio Production and Editing: EMBL Alumni Relations Content and Interviews: Angus Lamond and Thomas Vaccari Music: Eco Technology by Aleksey Chistilin from Pixabay Thanks to: EMBL Audiovisual and EMBL Design Sponsored by: EMBLEM © European Molecular Biology Laboratory (EMBL)