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Step into the world of Decoding Health, where Dr. Urban A. Kiernan and renowned experts delve into a myriad of fields, unraveling the complexities of science and its practical applications in our daily health. This show is committed to illuminating topics ranging from personal health and wellness to cutting-edge biopharmaceutical advancements and beyond.
Join us each week for an enlightening journey through the realms of science and discover the incredible tools that can enhance your everyday life.
Dr. Urban A. Kiernan holds a Ph.D. Bio-Analytical Chemistry from Arizona State University. His use of the title “doctor” or “Dr.” is in relation to himself and solely refers to that degree as an expert who has significantly contributed to his specific field of science. This video is for general informational purposes only. It should not be used to self-diagnose and it is not a substitute for a medical exam, cure, treatment, diagnosis, and prescription or recommendation. He does not hold any license or credentials for clinical/patient care and any information provided does not create a doctor-patient relationship between Dr. Urban A. Kiernan and you. You should not make any change in your health regimen or diet before first consulting a physician, or equivalent licensed medical provider, and obtain a medical exam, diagnosis, and other recommendations. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition and establishment of treatment plan.
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166 Episodes
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Send a text In this episode of Decoding Health, Dr. Urban A. Kiernan sits down with Tony Drake—lifestyle transformation coach, former WWF wrestler, and the man who lost 130 pounds and dropped from ~40% body fat to ~6%—to unpack what actually drives sustainable fat loss and lasting metabolic health. Tony shares the pivotal mindset shift that forced “Big T” to die, how consistent training and nutrition rewired his identity, and how that transformation opened doors to wrestling with WWE/WWF and ...
Send a text In this episode of the Decoding Health, Dr. Urban Kiernan breaks down the science behind Urolithin A, a gut-derived compound gaining attention for its role in mitochondrial health, muscle performance, and metabolic function. The conversation explains what Urolithin A actually is (and what it isn’t), how it’s produced through the gut microbiome, and why it’s fundamentally different from peptides. Dr. Urban walks through the concept of mitophagy—the cellular process that clears dama...
Send us a text Dr. Kaitlin Castillo pulls back the curtain on why so many people can look healthy on the outside while quietly living in a metabolic “danger zone” underneath the surface. Using real-world clinical context, she breaks down what processed, packaged eating does to blood sugar regulation, why insulin resistance can progress for years before patients are clearly warned, and what “good doctor” communication should look like when labs start trending in the wrong direction. The conver...
Send us a text GHK-Cu (copper peptide) has surged in popularity across regenerative medicine, aesthetics, and biohacking—but what does the science actually say? In this episode of Decoding Health, Dr. Urban breaks down the real physiology behind GHK-Cu, a naturally occurring copper-binding tripeptide composed of glycine, histidine, and lysine. You’ll learn how this peptide supports wound healing, collagen remodeling, tissue regeneration, and why it’s increasingly used for skin rejuvenation an...
Send us a text Ronald M. Krauss joins the show for a practical, myth-busting deep dive into cardiometabolic risk, lipidology, and why the LDL conversation is often framed in the wrong direction. Building on his long-standing advisory-level relationship with Dr. Urban and his “disruptor” approach to improving outcomes, Dr. Krauss clarifies the critical difference between LDL and LDL cholesterol, uses a memorable “bus cholesterol” analogy to explain particle number vs. cholesterol content, and ...
Send us a text GLP-1 is a gut-derived hormone designed to signal the pancreas to produce insulin—but in its natural form, it’s notoriously short-lived. In this Decoding Health segment, we break down why endogenous GLP-1 has an ultra-short half-life (about three minutes), and how the enzyme DPP-4 rapidly “clips” incretin hormones by targeting specific amino acids near the N-terminus—effectively destroying the signal before it can last. You’ll learn how GLP-1 receptor agonist drugs were enginee...
Send us a text Dr. Robert H. Lustig joins the show to break down why today’s metabolic health crisis is not a personal failure problem, but an environment problem, and how the power structure shaping food, policy, and public health has shifted in ways most people have not tracked. From “poisonous calories” and ultra-processed food to microplastics, reactive species, and artificial sweeteners, Dr. Lustig connects the biochemical dots to the brain, explaining how the amygdala functions like an ...
Send us a text In this episode of Decoding Health, we examine a recent shift in CDC guidance regarding hepatitis B vaccination recommendations for newborns. Long criticized for lagging behind evolving science, the CDC has now revised its position after reviewing updated risk-benefit data presented during a publicly broadcast panel discussion. Sparked by the birth of the host’s second grandchild, the conversation breaks down how hepatitis B is transmitted, why infection risk for infants born t...
Send us a text This episode featuring Dana Swope explores the intersection of nutrition, movement, stress, and metabolic health through an open, thought-provoking conversation. The discussion highlights how prioritizing protein and whole foods can reduce overall calorie needs while significantly increasing satiety, signaling a meaningful shift in how we approach sustainable nutrition. The episode also addresses the critical role stress plays in weight loss, reinforcing that meaningful fat los...
Send us a text This episode breaks down the Amylase test and its critical role in digestion, metabolic health, and personalized nutrition. The conversation explores how amylase activity impacts carbohydrate processing, energy levels, and blood sugar response, highlighting why a one-size-fits-all approach to diet does not work. Listeners learn how simple indicators like taste response and timing windows can reveal enzyme efficiency, when to pull back on certain carbs, and what low amylase acti...
Send us a text In this episode of Decoding Health, Dr. Urban A. Kiernan is joined by Dr. Don Clum for an in-depth, science-driven discussion on fasting, insulin regulation, and metabolic health—cutting through popular misconceptions to explain what fasting actually is and how it impacts the body. The conversation begins with how early insulin research led to modern fasting protocols and clarifies the difference between time-restricted eating, intermittent fasting, and true fasting. Dr. Clum e...
Send us a text In this episode of Decoding Health, Dr. Urban A. Kiernan breaks down the science behind vaccine adjuvants—what they are, why they are used, and how they influence immune responses. Drawing from his experience in biotechnology and pharmaceutical research, he explains how adjuvants enhance antibody production and increase the body’s overall biological workload. We explore commonly used compounds such as aluminum salts and newer immune-stimulating agents, while examining concerns ...
Send us a text In this episode, Dr. Evan Nadler challenges some of the most common misconceptions surrounding childhood and adolescent obesity—starting with the idea that it’s simply a result of poor diet or lack of willpower. Drawing on more than two decades of clinical, surgical, and research experience, he explains why obesity is a chronic disease, why BMI is an unreliable diagnostic tool, and how true risk should be assessed based on physical and mental health impact. The conversation exp...
Send us a text What are the real side effects of Vyleesi—and how do they compare to Viagra? In this follow-up conversation, Dr. Urban A. Kiernan breaks down what Vyleesi (also known as PT-141) is, how it works, and why it’s being discussed as a modern option for women experiencing low sexual desire, arousal challenges, or vaginal dryness (when prescribed for specific diagnoses). You’ll learn how Vyleesi’s mechanism differs from Viagra’s nitric-oxide-driven vasodilation, why Vyleesi is deliver...
Send us a text Michal Ofer shares the personal turning point that reshaped her entire approach to health—going from taking 30 pills a day at 35 to stepping away from medications and focusing on root-cause inputs that actually move the needle. She breaks down how diet directly affects stress tolerance, which foods tend to be most inflammatory, and why food quality can feel dramatically different across countries (and even compared to earlier eras in the U.S.). The conversation also compares he...
Send us a text In this holiday quick-hit episode of Decoding Health, Dr. Urban A. Kiernan sits down with Leila Adnani (PS Creative Studios) to close out 2025 and set the tone for a stronger 2026—without the fake “new year, new me” hype. Leila shares what PS Creative Studios is focused on heading into the new year, including a strategic reset around what to keep, what to cut, and what to build in 2026. The conversation turns into a practical take on why most New Year’s resolutions fail, how to...
Send us a text This Decoding Health episode follows the real-time journey of Keiran Meekins, a young athlete living with spastic diplegia cerebral palsy, as he undergoes an integrated evaluation and treatment process combining advanced physical therapy and emerging V-cell therapy. Recorded on location in Arizona, the episode brings listeners inside a full clinical assessment, gait analysis, neurological measurements, and post-treatment movement improvements. Through candid conversations with ...
Send us a text This episode examines the complex relationship between cholesterol, statin use, and Parkinson’s disease through a data-informed and critically minded discussion. The conversation challenges common assumptions about cholesterol suppression, exploring how statins can interfere with the body’s natural cholesterol production and why that matters for brain and neurological health. The episode addresses heart attack statistics in context, encouraging listeners to move beyond fear-bas...
Send us a text Gary Jackson joins Dr. Urban to unpack how discipline, mindset, and behavior patterns shape metabolic health. They explore why today’s “normal” encourages unhealthy habits, how marketing drives cravings, why the word “treat” programs reward behavior early in life, and how simple tools like label-reading can shift daily decisions. Gary shares the core coaching principles he teaches in judo—structure, repetition, accountability, and identity—and explains why sustainable cha...
Send us a text The internet is buzzing about “GLP-3,” but according to Dr. Urban, it doesn’t exist. In this episode, he breaks down why GLP-3 is nothing more than a marketing term tied to a still-experimental drug from Eli Lilly. Dr. Urban explains the real science behind GLP-1 and GLP-2, how these hormones naturally function in the body, and why the new triple-agonist compound being called “GLP-3” is not approved, not regulated, and absolutely not safe for consumer use. The conversation expo...
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