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Dr. Joseph Mercola - Take Control of Your Health
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Dr. Joseph Mercola - Take Control of Your Health

Author: Dr. Mercola

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Listen to Dr. Mercola's Weekly Podcast, as the legendary natural health pioneer continues to lead you on your journey towards optimal health.
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What you eat before and after hard workouts shapes how much internal stress your body experiences and how quickly you recover Eating carbohydrates before high-intensity training helps limit excessive stress during the workout and protects your ability to train consistently Whole foods rich in natural antioxidants support recovery after exercise without interfering with the signals that drive training progress Relying on antioxidant supplements or frequent high-intensity sessions backfires by disrupting recovery and slowing improvement Matching food timing, training intensity, and recovery allows exercise stress to build strength instead of draining energy and motivation
A McGill University study found that childhood adversity combined with altered brain insulin signaling increases metabolic disease risk in women, even before clinical signs like diabetes or heart disease appear Early stress reprograms brain regions that govern reward, impulse control, and energy balance, raising visceral fat storage and disrupting insulin sensitivity decades after the original stress occurred Women with higher brain insulin signaling activity were more vulnerable to metabolic harm from childhood stress, showing greater fat gain and a higher risk for metabolic syndrome than men Stress-related metabolic disruption often remains undetected because changes like visceral fat buildup and inflammation occur below standard clinical thresholds, delaying recognition until the disease is more advanced Reducing ongoing stress, improving insulin sensitivity, limiting linoleic acid (LA) intake, restoring energy production, and supporting hormonal balance can help counteract early stress and lower long-term metabolic risk
SSRI antidepressants are one of the most harmful medications on the market, and because of just how many people they are given to (often for no good reason as only a minority of patients benefit from SSRIs) they have had a profound effect on the consciousness of our entire society This article will review some of the more common side effects of SSRIs (and SNRIs), such as losing the ability to have sex, becoming numb to life, becoming severely agitated or imbalanced (sometimes to the point one becomes violently psychotic or commits suicide), losing your mind, and the development of birth defects Like many other stimulant drugs (e.g., cocaine) SSRIs can be very difficult to quit. Because of this, patients frequently get severely ill when they attempt to stop them (withdrawals affect roughly half of SSRI users). Worse still, it is often extremely difficult to withdraw from them and very few doctors know how to safely facilitate this Due to widespread denial in psychiatry about the issues with their drugs the common SSRI side effects (e.g., withdrawals) are often misinterpreted as a sign the individual had a pre-existing mental illness and needs more of the drug — which all too often then leads to catastrophic events for the over-medicated patient This article will provide the critical information SSRI patients are rarely warned about and resources for patients already trapped in challenging mental health situations  
Fear-based learning can intensify pain in people with IBD even when inflammation is no longer active, showing that emotional processing plays a major role in chronic symptoms IBD patients in remission reported significantly higher pain intensity and unpleasantness compared to healthy individuals, despite experiencing the exact same heat stimulus The brain can hold onto pain memories through a process called fear conditioning, which teaches the nervous system to expect discomfort even without a current physical trigger People with IBD often feel isolated and emotionally overwhelmed due to unpredictable flare-ups, brain fog, shame, and the invisible nature of their pain Therapies like cognitive behavioral therapy offer a promising path to reduce pain by addressing the brain's learned fear responses
Birth defects affect one in 33 babies, making them the top cause of infant death A study published in Environmental Research found that real-world PFAS mixtures can disrupt placental functions during the first trimester of pregnancy Other studies have also associated PFAS exposure with preeclampsia, changes in placental DNA, and nervous system defects during pregnancy Sources of PFAS at home include cosmetics, non-stick pans, infant clothing, and certain clothing Reducing PFAS exposure is challenging, but filtering water properly, making smart swaps in the kitchen, and opting for natural fabrics is a good start
New research shows that restoring glucose oxidation through the PDH enzyme — not burning more fat — is the key driver of meaningful and sustainable fat loss Obese animals lost fat while preserving muscle once PDH activity was restored, revealing a metabolic repair pathway that supports long-term weight control and higher energy Human muscle studies show that people with flexible fuel switching burn fat during fasting and glucose after meals, while metabolically rigid muscle stays stuck and promotes fat storage Fitness-focused interventions improve insulin sensitivity by strengthening mitochondrial function and restoring proper timing between fat use and glucose handling You can repair this system by lowering dietary fat, increasing healthy carbohydrates, supporting PDH with key nutrients, and using strategic movement to rebuild metabolic flexibility
About 13.4% of U.S. women of reproductive age struggle with infertility, leading many to pursue assisted reproductive technologies (ARTs) like in vitro fertilization ARTs help initiate pregnancy but raise concerns such as multiple births, high financial costs, ovarian hyperstimulation syndrome, elevated stress, and emerging evidence linking them to long-term heart disease risk A long-term study that followed women for 12 years found each additional ART cycle was associated with higher cardiovascular disease risk The increased cardiovascular risk centered on pulmonary embolism and deep vein thrombosis, showing that ART-related heart risk involves dangerous clot formation rather than gradual blood pressure or artery disease Programmed frozen embryo transfer cycles showed stronger heart disease associations, highlighting that hormone protocol choices during fertility treatment can influence long-term cardiovascular outcomes years after pregnancy
Regular energy drink use pushes your heart and blood vessels into a constant stress state that medications and fitness can't override while stimulants remain in your system Severe blood pressure spikes and dangerous heart rhythm events have occurred in people drinking energy drinks who appeared healthy and had no prior heart disease Energy drinks stack caffeine with other stimulants and added sugar, creating a combined strain that overwhelms normal cardiovascular control mechanisms Low cellular energy drives the urge to rely on stimulants, but energy drinks mask the problem rather than restoring real energy production Removing energy drinks and rebuilding cellular energy through food, movement, and daily structure helps your heart regain stability and lowers real cardiovascular risk
Modern diets hide excessive phosphate additives in ultraprocessed foods, which are absorbed rapidly and efficiently, disrupting natural mineral balance and overwhelming organs far more severely than refined sugar Industrial phosphate additives enhance texture, flavor, and shelf life, increasing total intake by 40% or more compared to natural sources, leading to widespread hidden overconsumption Chronic phosphate overload hardens arteries, stresses kidneys, elevates blood pressure, and accelerates aging, even when blood tests appear normal or phosphate levels stay within conventional ranges Elevated phosphate triggers excess fibroblast growth factor-23 (FGF-23), harming the heart, hormones, and metabolism, while weakening bones and increasing fracture risk through calcium imbalance Avoiding ultraprocessed foods and choosing whole, natural ingredients lowers phosphate load, improves cardiovascular and kidney function, restores mineral balance, and promotes long-term health and vitality
Sleeping fewer than seven hours a night shortens lifespan more than poor diet, lack of exercise, or weak social ties, making sleep one of the strongest predictors of long-term survival Short sleep accelerates aging by disrupting cellular repair, hormone balance, and energy production, even in people who eat well and stay physically active Most adults are not metabolically resilient enough to function on limited sleep, which means chronic sleep loss quietly compounds damage year after year Small, consistent sleep deficits add up over time, increasing vulnerability to disease and reducing your body's ability to recover from stress Restoring sleep quality by stabilizing light exposure, circadian timing, and nightly routines gives your body the conditions it needs to repair itself and extend health span
Plastic cutting boards shed microplastics during routine food prep, contributing to increased plastic ingestion that accumulates in organs like the brain and reproductive tissues over time Research shows knife pressure releases hundreds of plastic fragments per cut, many embedding into food tissue and remaining even after rinsing or cooking Older, heavily grooved boards release more microplastics, as repeated knife strokes and surface wear accelerate abrasion and contamination during everyday meal prep Replacing plastic boards with wood, bamboo, or glass reduces microplastic exposure, while proper cleaning and timely replacement help limit bacterial and chemical risks Beyond cutting boards, reducing exposure to microplastics requires filtering water, avoiding plastic packaging, choosing natural fabrics, and addressing hormone disruption caused by estrogen-mimicking plastic chemicals
Over half of Americans now live with neurological disorders, which significantly impact disability levels and quality of life. Tension headaches, migraines, stroke, and Alzheimer's are major contributors Neurological burden varies by region, with Southern states experiencing worse outcomes. Despite medical advances, mortality has decreased but long-term disability has increased due to longer lifespans Global brain-related disorders cost $1.7 trillion annually, with stroke and dementia the most expensive. High-income countries spend disproportionately more while lower-income nations face severe resource shortages Aging populations and rising care costs strain health systems, as inpatient and long-term care dominate expenses. Uneven access means outcomes depend heavily on geography, income, and health care infrastructure Improving neurological health requires targeting mitochondrial dysfunction through lowered linoleic acid intake, gradual gut repair, reducing electromagnetic field and plastic exposure
Belly fat changes how your heart is built and works, even when your weight and body mass index (BMI) appear normal Men face earlier and more severe heart damage because they store more fat deep in the abdomen, which increases pressure on the lungs and forces the heart to work harder with every breath Standard scales miss this risk, but simple waist measurements reveal hidden stress on your heart long before symptoms appear Beer bellies form when cellular energy fails, pushing fuel into fat storage instead of burning it for daily function Restoring metabolism through food choices, gut repair, and daily movement reduces belly fat and protects heart structure over time
Women with psoriasis consistently show lower progesterone and DHEA, two hormones that normally quiet inflammation, making flare-ups stronger and more frequent Estrogen dominance — where estrogen feels too strong relative to progesterone — heightens immune reactivity and explains why symptoms worsen before your period, after childbirth and during menopause Intracellular estrogen, not blood estrogen, drives inflammation in psoriatic skin, which is why your labs can look "normal" even when your symptoms intensify Long-term hormone replacement therapy increases psoriasis risk by overstimulating inflammatory pathways, especially in post-menopausal women whose hormones are already shifting You can ease flare patterns by supporting progesterone and DHEA, eliminating estrogen-mimicking triggers, avoiding seed oils, optimizing vitamin D and reducing stress-related hormonal strain
Rosacea often worsens in midlife because years of inflammation prevent blood vessels from fully recovering between triggers, making redness more persistent An overactive immune response keeps inflammatory signals switched on, which drives flushing, burning, and visible blood vessels even without obvious triggers Gut imbalance fuels facial inflammation by sending immune signals into your bloodstream that keep skin cells reactive and slow recovery Processed foods, including seed oils, increase inflammatory load, while stabilizing digestion and reducing daily stressors lowers flare frequency Addressing root drivers such as diet, gut health, and emotional stress reduces reactivity and helps your skin regain the ability to reset
Walking 5,001 to 7,500 steps a day slows the buildup of tau, the brain protein linked to Alzheimer's-related decline, helping you stay sharper for years longer Older adults with elevated amyloid — a key early Alzheimer's marker — preserved memory and daily function far better when they consistently reached a moderate step range Even small increases in movement, such as moving from under 3,000 steps to 3,500 to 5,000 per day, deliver meaningful cognitive benefits without requiring intense exercise High-intensity training pushed healthy adults into metabolic dysfunction, reducing mitochondrial energy production by about 40% and disrupting blood sugar stability Finding your personal exercise "sweet spot" — enough movement to avoid inactivity without pushing into extreme training — protects both long-term brain health and daily metabolic balance
Eating five or more servings of ultraprocessed foods (UPFs) a day nearly doubles your risk of developing Crohn's disease Additives like emulsifiers, thickeners, and artificial sweeteners found in ultraprocessed foods break down the gut's protective mucus barrier and fuel chronic inflammation High intake of UPFs is linked to changes in gut bacteria that reduce diversity and promote the growth of harmful strains associated with inflammatory bowel disease (IBD) flare-ups Common UPFs like white bread, frozen meals, sauces, and breakfast cereals show the strongest links to increased Crohn's risk Removing seed oils, emulsifiers, and UPF-heavy meals while focusing on gut-repairing whole foods can help reduce flare frequency and support long-term healing
A new Nutrients study shows that drinking 12 ounces of 100% elderberry juice daily for a week helped overweight adults activate more genes that regulate how the body uses energy after meals than a placebo Elderberry juice turned on processes that help the body manage energy better — making it easier to switch between burning carbohydrates and fat for fuel Earlier research from Washington State University showed elderberry juice improved blood sugar control, increased fat burning, and shifted energy use during meal challenges Practical tip: Aim for about 12 ounces of unsweetened, 100% elderberry juice daily for seven days. Check labels to avoid added sugars, as unsweetened juice still contains about 30 to 36 grams of natural sugar per eight-ounce serving Safety first: Never eat raw elderberries, check for medication interactions (such as immunosuppressants or diabetes drugs), and consult a healthcare provider before using if you are breastfeeding or have an autoimmune condition
Winter worsens migraines because cold, darkness, and routine disruption overload your nervous system and reduce your brain's ability to regulate pain signals Seasonal drops in light exposure disrupt melatonin and circadian rhythm, lowering your brain's resilience and increasing headache frequency and intensity Excess LA from seed oils damages mitochondrial energy production, making your brain more reactive to stress and more prone to migraine attacks in any season Stable daily patterns — consistent sleep timing, hydration, meals, and movement — reduce neurological stress and raise your migraine threshold Restoring cellular energy by lowering LA intake and supporting mitochondrial function helps your brain stay calm, resilient, and less reactive year-round
Parkinson's disease is rising rapidly worldwide, and most cases are driven by lifestyle and environmental stressors rather than genetics, meaning daily choices play a powerful role in risk and progression The disease often begins years before diagnosis, with early signs like poor sleep, digestive issues, anxiety, and fatigue signaling stress on your brain long before tremors appear Chronic inflammation, toxin exposure, poor sleep, and metabolic strain weaken dopamine-producing neurons, but improving sleep, movement, diet, and stress regulation slow this damage Supporting gut health, reducing exposure to environmental toxins, and maintaining steady energy through proper nutrition help protect your brain and preserve mobility and cognition Consistent habits that lower stress, improve sleep quality, encourage movement, and support vitamin D balance give your brain the conditions it needs to stay resilient over time
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Comments (30)

Dingus

this ai nonsense is such a shame. used to love to listen but cannot bear the ai

May 12th
Reply

Morlin Buchnor

I don't like the AI voices.

Apr 26th
Reply

J D

what happened to DR mercola?

Mar 26th
Reply

Christina Mancini

these shorts stink. mindless and useless. if we can't know that a podcast us actually Dr. mercola speaking, I will unsubscribe altogether.

Mar 11th
Reply

Christina Mancini

well, these folks seem nice, but I wouldn't bother listening to their drivel again.

Mar 4th
Reply

L K

synchronization leads to motivation, etc.

May 25th
Reply

L K

light exposure 100-1000x differential

May 25th
Reply

George Scott

So 7KetoDHEA is bad for you??

Dec 22nd
Reply

Christina Mancini

brilliant!!!

Dec 12th
Reply

Christina Mancini

just about everything he says about nutrition is nonsense. I wasted my $ on his book. no, I won't eat soy and veg based proteins.

May 12th
Reply (3)

Brenda Montgomery

This guest didn’t say anything different than what you and others have already said. He was worthless. I would never buy his book. Disappointed.

Feb 27th
Reply

Christopher Czech

Mr Kennedy's audio is terrible. I could barely understand him.

Dec 16th
Reply

Patricia Caroca

Thank you so much for this podcast! Seeds of Hope and Truth!We don't have the luxury of being hopeless. Thank you both!

Dec 4th
Reply

sara

LinoleicAcid-wise🥴

Dec 3rd
Reply

📩 Raymond J. Negron💎

ONE OF THE TOP PODCASTS I LISTEN TO - TO KEEP ME TRULY INFORMED 🙌 ABOUT LIFE & HEALTH. THE SAYING GOES SOMETHINT LIKE " THE RICHEST MAN IN THE 🌎 WORLD HAS JUST ONE WISH." WHAT DO YOU THINK HE WANTED? DR. JOE IS SPOT ON WITH YOUR HEALTH-- LISTEN IN. GRAB A PEN AND PAPER TO TAKE NOTES AND EXTEND YOUR LONGEVITY... AS WHAT YOU LEARN IS BELOW THE SURFACE...

Nov 3rd
Reply

Paul Bass

this is amazing

May 4th
Reply (1)

Chris Greive

It's interesting to see this supplement, having used Megahydrate before and accidentally stopped my eczema after 40yrs of bother, and look fwd to more 'simple' medicine alternatives

Jan 12th
Reply

George Scott

Thanks for Considering individuals who travel alot or who live in an apartment... Most cant implement systems.. But a shower filter can be applied in most cases...

Sep 23rd
Reply

Bekki Boo

Really enjoyed your podcast on KetoFast Q&A, so informative. I've bought your book and looking forward to trying the KetoFast program. Thanks and keep up your amazing work!! 😀

Jul 8th
Reply

Niclas Daniels

20:13 #mushrooms can be used as a treatment for #neuropathy 22:15 #blueOcean

Jun 23rd
Reply