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JAMA Clinical Reviews

Author: JAMA Network

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Author interviews that explore the latest clinical reviews.
471 Episodes
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Accurate assessment of intravascular volume facilitates decisions about fluid management in patients with volume overload. Author Edmund A. Liles Jr, MD, of the University of Utah joins JAMA Associate Editor David Simel, MD, MHS, to discuss best evidence from physical exam findings including ultrasound, radiographs, and lab studies for determining volume overload in spontaneously breathing patients. Related Content: Does This Patient Have Volume Overload?
Type 1 diabetes affects approximately 2 million people in the US and 8.4 million people worldwide. Author Desmond Schatz, MD, of the University of Florida joins JAMA Deputy Editor Mary M. McDermott, MD, to discuss current evidence regarding diagnosis and treatment of type 1 diabetes. Related Content: Type 1 Diabetes
Mark Cuban, entrepreneur, investor, and cofounder of the Mark Cuban Cost Plus Drug Company, joins JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, to discuss the role of pharmacy benefit managers, insurance formularies, and opaque pricing practices that shape how most Americans access prescription drugs. Hear why he thinks doctors are the good guys in a broken system. Related Content: Pharmaceutical Pricing—JAMA Talks With Mark Cuban
Opioid use disorder is the third most prevalent substance use disorder worldwide. Author Alexander Walley, MB, MSc, of Boston Medical Center and Boston University joins JAMA Deputy Editor Kristin Walter, MD, MS, to discuss the efficacy, safety, and practical considerations of treating patients with medications for opioid use disorder, opioid withdrawal, and opioid overdose. Related Content: Medications for Opioid Use Disorder, Opioid Withdrawal, and Opioid Overdose
Ovarian cancer may be prevented with removal of the fallopian tubes during pelvic or select abdominal surgery in eligible women. This procedure, opportunistic salpingectomy, can be offered to more eligible women. Author Jurgen M. Piek, MD, PhD, of the Catharina Cancer Institute discusses this and more with JAMA Deputy Editor Linda Brubaker, MD, MS. Related Content: Opportunistic Salpingectomy for Prevention of Tubo-Ovarian Carcinoma
IgA nephropathy is a chronic kidney disease involving deposition of IgA-containing immune complexes in the glomerulus, which often causes kidney failure within 10 to 20 years. Author Michelle Marie O'Shaughnessy, MB, BCh, BAO, MS, of Galway University joins JAMA Deputy Editor Kristin Walter, MD, MS, to discuss the symptoms, risk factors, diagnosis, treatment, and prognosis of IgA nephropathy in adults. Related Content: IgA Nephropathy in Adults
Restless Legs Syndrome

Restless Legs Syndrome

2026-01-2123:25

Restless legs syndrome is a sleep-related neurologic disorder that causes an overwhelming urge to move the limbs, which can cause substantial sleep disturbance. Author John W. Winkelman, MD, PhD, of Harvard Medical School joins JAMA Deputy Editor Kristin Walter, MD, MS, to discuss the symptoms, risk factors, diagnosis, and treatment of restless legs syndrome. Related Content: Restless Legs Syndrome
Mifepristone used with misoprostol is the most common abortion regimen in the US. It is also a focal point of reproductive health policy and politics, with controversy over its legal status and regulation by the US Food and Drug Administration (FDA). Author G. Caleb Alexander, MD, MS, from Johns Hopkins discusses this and more with JAMA Deputy Editor Joseph S. Ross, MD, MHS. Related Content: The US Food and Drug Administration's Regulation of Mifepristone Politics, Science, and the Future of FDA Drug Regulation
Incidence rates of gastric cancer in younger individuals are on the rise and gastric cancer is the fifth-leading cause of cancer-related deaths worldwide. JAMA Review author Haeseong Park, MD, MPH, from the Dana Farber Cancer Institute, discusses this and more with JAMA Senior Editor Karen Lasser, MD, MPH. Related Content: Gastric Cancer
JAMA Deputy Editor Mary McDermott, MD, and JAMA Deputy Editor Kristin Walter, MD, MS, highlight their selections of top JAMA Clinical Reviews podcasts in 2025. Related Content: Managing Adverse Effects of Obesity Medications Diagnosis and Management of Hypothyroidism Type 2 Diabetes: Diagnosis and Current Guidelines for Treatment Managing Adverse Effects of Incretin-Based Medications for Obesity Hypothyroidism Diagnosis and Treatment of Type 2 Diabetes in Adults JAMA Editors' Choice 2024: Clinical Reviews Podcasts
In this episode, JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, and Medical News Director Jennifer Abbasi discuss the journal's inaugural Research of the Year roundup. Related Content: Research of the Year 2025
Obesity affects more than 1 billion people worldwide and is recognized by the World Health Organization as a chronic, relapsing disease. WHO recently published a guideline in JAMA on the use and indications of GLP-1 therapies for the treatment of #obesity in adults. Francesca Celletti, MD, PhD, and Ezekiel Emanuel, MD, PhD, join JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, to discuss. Related Content: World Health Organization Guideline on the Use and Indications of Glucagon-Like Peptide-1 Therapies for the Treatment of Obesity in Adults
Head and Neck Cancer

Head and Neck Cancer

2025-12-1518:28

Head and neck cancer is the seventh most common cancer worldwide and is commonly associated with tobacco and alcohol use, or human papillomavirus (HPV) infection. Author Lara Dunn, MD, of Memorial Sloan Kettering Cancer Center joins JAMA Associate Editor Margaret Wheeler, MD, to discuss the epidemiology, risk factors, diagnosis, treatment, and prognosis of head and neck cancer. Related Content: Head and Neck Cancer
Allergic rhinitis affects about 1 in 6 US adults. A recent JAMA Insights summarizes evidence regarding the associations of climate change and air pollution with allergic rhinitis and sinusitis. The discussion includes prevention and management strategies. Coauthor Neelima Tummala, MD, joins JAMA Deputy Editor Mary McDermott, MD, to discuss. Related Content: Climate Change, Allergic Rhinitis, and Sinusitis
Clinicians should weigh benefits against risks when engaging patients in informed discussions about cannabis or cannabinoid use. Kevin Hill, MD, MHS, of Harvard Medical School joins JAMA Senior Editor Karen Lasser, MD, MPH, to discuss the current evidence about the therapeutic use of cannabis and cannabinoids in adults, potential harms, and evidence-based clinical guidance. Related Content: Therapeutic Use of Cannabis and Cannabinoids
Peripheral neuropathy affects approximately 1% of adults worldwide and can be associated with significant disability. Author Michelle Mauermann, MD, of the Mayo Clinic in Minnesota joins JAMA Deputy Editor Mary M. McDermott, MD, to discuss diagnosis and optimal management of peripheral neuropathy. Related Content: Peripheral Neuropathy
Metabolic dysfunction-associated steatotic liver disease (MASLD), an increasingly prevalent condition among adults worldwide, is associated with liver-related complications, hepatocellular carcinoma, and certain extrahepatic cancers. Author Norbert Stefan, MD, from the University Hospital of Tübingen in Tübingen, Germany, discusses this and more with JAMA Deputy Editor Kristin Walter, MD, MS. Related Content: Metabolic Dysfunction–Associated Steatotic Liver Disease in Adults ----------------------------------- JAMA Editors' Summary
The JAMA Summit on Firearm Violence convened 60 thought leaders from a wide array of disciplines to chart a roadmap that could lead to substantial reductions in firearm harms by 2040. Frederick P. Rivara, MD, MPH, of the University of Washington joins JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, to discuss the Summit and steps that could lead to a safer world by 2040. Related Content: Toward a Safer World by 2040 Reducing Firearm Violence and Harms ----------------------------------- JAMA Editors' Summary
Keratinocyte carcinomas, which include basal cell carcinoma and squamous cell carcinoma, are common forms of skin cancer. Approximately 5.4 million keratinocyte carcinomas are diagnosed in the US annually. Author Mackenzie R. Wehner, MD, MPhil, of the University of Texas MD Anderson Cancer Center joins JAMA Associate Editor David Simel, MD, MHS, to discuss treatment of these types of nonmelanoma skin cancer. Related Content: Keratinocyte Carcinoma ----------------------------------- JAMA Editors' Summary
Lung cancer in nonsmoking individuals is increasing worldwide and currently accounts for 15% to 20% of lung cancer cases globally. Benjamin Solomon, PhD, of the Peter MacCallum Cancer Centre in Melbourne, Australia, discusses the epidemiology and treatment of lung cancer in nonsmoking patients with JAMA Deputy Editor Kristin Walter, MD, MS. Related Content: Lung Cancer in Nonsmoking Individuals ----------------------------------- JAMA Editors' Summary
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Comments (19)

Angela Preda

Why only men?

May 15th
Reply

Azura Bennett

Certainly! Author interviews diving into the latest clinical reviews offer an invaluable perspective.

Dec 21st
Reply

ali bana

very useful 👍🌹

Oct 18th
Reply

tim jennings

I'm unsure why this podcast episode was published. The host spends the entirety of the episode fighting over the word racism because he thinks racism is illegal and doesn't exist anymore. That's very clearly not the case (we just had Trump as a president, BLM marches, and insane COVID-19 disparities) so maybe he's not the right guy to be hosting something related to structural racism? The guest was okay but because the host was so caught up on the racism word, they got nothing accomplished over 15 minutes and made a fool of themselves in the name of JAMA.

Mar 4th
Reply

Amirhossein Azari Jafari

that was such a wonderful story. I was on my cancer article while I was listening to this episode and honestly I shocked and it got me to think carefully. Dr. Stern, deep down in my heart, I wish u the best, Do not lose your hope and always be strong.

Aug 23rd
Reply

Lucy K

I guess this podcast got it totally wrong. Tunnel vision.

Apr 10th
Reply

Prasad Chalasani

Shockingly bad advice — “asymptomatic people don’t need to wear masks in a grocery store”. It’s been established that people shed virus for up to as much as a week before showing symptoms, if the develop them at all. This advice is doing a huge disservice, I urge you to fix this

Apr 6th
Reply (2)

zahra aghajanzadeh

.

Mar 21st
Reply

Jon Elliott

such crap. no mention of the well-known and understood cause and cure of CAD - DIET AND LIFESTYLE. No surprise that OMT has limited and minimal efficacy when the engine of CAD us left running.

Mar 8th
Reply

Nuage Laboratoire

text

Mar 1st
Reply

Yasmine C

Unprofessional behavior leads to complications?! who woulda thunk it?

Feb 28th
Reply

Christal Cooper

didn't ask for this movies

Feb 28th
Reply

Matt Bowen

God Bless the American Soldier

Nov 28th
Reply (1)

Nathan Birch

9 d

Jul 25th
Reply (1)

Rodrigo Py

Amazing, episode!

May 21st
Reply
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