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Cardiac Consult: A Cleveland Clinic Podcast for Healthcare Professionals
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Cardiac Consult: A Cleveland Clinic Podcast for Healthcare Professionals

Author: Cleveland Clinic Heart & Vascular Institute

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A Cleveland Clinic podcast exploring heart, vascular and thoracic topics of interest to healthcare providers: medical and surgical treatments, diagnostic testing, medical conditions, and research, technology and practice issues.
346 Episodes
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Luke Laffin, MD, and Steven Nissen, MD, discuss findings from SURPASS-CVOT, including a secondary analysis evaluating broader cardiovascular and renal outcomes with dual GLP-1 and GIP agonist therapy compared with a first-generation GLP-1 agent. The conversation examines outcomes of the therapy on all-cause mortality and the clinical implications for treating patients with diabetes and high cardiovascular risk. View current clinical trials. https://my.clevelandclinic.org/departments/heart/cl...
Steven Nissen, MD, and Luke Laffin, MD, discuss late-breaking data from the Phase II KARDINAL Trial evaluating Tonlamarsen, a once-monthly therapeutic for uncontrolled multidrug therapy. They review study design, blood pressure outcomes and the potential clinical role of long-acting injectable therapies to address adherence gaps in real-world hypertension management. View current clinical trials. https://my.clevelandclinic.org/departments/heart/clinical-trials Looking to refer a patient? Pl...
Sean Lyden, MD, and Jon Quatromoni, MD, discuss the evolving landscape of vascular clinical trials, highlighting investigational therapies and device-driven innovations. Learn how these trials are shaping evidence-based decision-making, expanding minimally invasive options and influencing future standards of care for aortic, carotid, peripheral arterial and venous disease. View current clinical trials. https://my.clevelandclinic.org/departments/heart/clinical-trials Looking to refer a pati...
Lars Svensson, MD, PhD, and Milind Desai, MD, MBA, discuss contemporary evaluation and management of aortic valve regurgitation, emphasizing advanced imaging and optimal timing of intervention. They examine valve repair versus replacement, durability outcomes and lifetime management considerations at a high-volume valve center. Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.
Women’s cardiologist Tamanna Singh, MD, and sports medicine physician Marie Schaefer, MD, introduce the WISER (Women's Integrated Sports, Exercise and Research), a multidisciplinary program addressing the cardiovascular, musculoskeletal, and psychosocial needs of women athletes across the lifespan. They outline how its cross‑institute model integrates cardiology, orthopedics, nutrition, psychology, and sports social work to deliver coordinated, evidence‑driven care. Looking to refer a patien...
Eric Roselli, MD, and Patrick Vargo, MD, discuss the contemporary management of aortic coarctation in adults, including late complications, reintervention strategies, and evolving endovascular and hybrid approaches informed by decades of institutional experience. View the research: Late Complications of Aortic Coarctation Repair Can Be Safely Treated https://consultqd.clevelandclinic.org/late-complications-of-aortic-coarctation-repair Looking to refer a patient? Please reach ou...
Maria Mountis, DO, and Karlee Hoffman, DO, explore the complexities of pregnancy and parenthood in heart transplant recipients or those living with heart failure, highlighting multidisciplinary cardio‑obstetrics care. These heart failure experts explore the nuanced decision‑making required to balance maternal health, fetal safety and long‑term transplant outcomes, emphasizing the importance of preconception counseling for this complex population. Looking to refer a patient? Please reach out ...
The new Haslam-Bailey Family Section of Cardiovascular Genomics and Precision Medicine is integrating genomic data into cardiovascular risk assessment, diagnosis and treatment. Samir Kapadia, MD, and Krishna Aragam, MD, discuss practical applications of genetic testing and emerging gene‑targeted therapies to enable more proactive and precise patient care. Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.
Oussama Wazni, MD, MBA, and Jeffery Courson, DO, examine the evaluation and management of inherited arrhythmias and genetic cardiomyopathies. They discuss diagnostic strategies like genetic testing and advanced imaging, and the role of multidisciplinary care in precision medicine. The conversation also highlights evolving therapies, including individualized pharmacologic approaches and emerging gene-based treatments shaping the future of care. Looking to refer a patient? Please reach out to ...
Venugopal Menon, MD, and Abdulla Damluji, MD, discuss the emerging subspecialty of cardiovascular aging and the growing need to tailor cardiovascular care for older adults. They explore how integrating geriatric expertise into cardiovascular practice can improve diagnostic accuracy, individualize therapy and optimize outcomes for this rapidly expanding patient population. Read more about the Cardiovascular Center for Aging. https://consultqd.clevelandclinic.org/the-case-for-cardi...
Amar Krishnaswamy, MD, and Marijan Koprivanac, MD, discuss contemporary follow‑up strategies after TAVR and SAVR, highlighting advances in minimally invasive and robotic surgical approaches that significantly reduce recovery time and postoperative pain. They outline evidence‑based recommendations for cardiac rehabilitation and structured imaging surveillance, emphasizing the critical role of timely follow-ups to detect early valve‑related complications. Looking to refer a patient? Plea...
Explore the latest ACC/AHA guidelines on acute coronary syndromes with co-authors Venugopal Menon, MD, and Jacqueline Tamis-Holland, MD, joined by Donna Kimmaliardjuk, MD. This discussion covers key updates, including unified STEMI/non-STEMI recommendations, heart team decision-making for multivessel disease, evolving strategies for dual antiplatelet therapy, and the role of mechanical circulatory support in complex cases. Looking to refer a patient? Please reach out to our Physician Referra...
Stanley Hazen, MD, PhD, and Scott Cameron, MD, PhD, discuss emerging evidence linking gut microbiome-derived TMAO to abdominal aortic aneurysm development and progression. They explore its role as both a causative factor and a biomarker, review current risk stratification strategies and highlight future therapeutic approaches aimed at reducing TMAO levels to improve vascular outcomes. Learn more about the research. https://consultqd.clevelandclinic.org/tmao-can-predict-growth-of-abdominal-ao...
Hani Najm, MD, and Joanna Ghobrial, MD, discuss the evolving role of transcatheter pulmonary valve implantation in lifetime management of congenital heart disease patients. They explore patient selection, valve durability, imaging strategies for early detection of HALT or HAM and the collaborative heart team approach that optimizes outcomes. Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.
Venugopal Menon, MD, Director of the Coronary ICU, and Michael Tong, MD, cardiothoracic surgeon specializing in advanced heart failure, discuss contemporary management of post-infarction ventricular septal rupture, a rare but serious complication. They review the role of early transfer to high-volume centers and why definitive surgical closure remains the gold standard. Learn about the impact of temporary mechanical circulatory support on organ recovery and the timing of repair. Looking to r...
Kenneth McCurry, MD, and Marie Budev, DO, share Cleveland Clinic’s multidisciplinary approach to managing end-stage lung disease and advancing lung transplantation. They discuss innovations such as ex vivo lung perfusion (EVLP), ECMO bridging, and strategies for expanding donor and recipient criteria, including complex and multi-organ cases. The episode also highlights ongoing research and clinical trials aimed at improving post-transplant outcomes and reducing chronic rejection. Looking to ...
Samir Kapadia, MD, Chairman of Cardiovascular Medicine at Cleveland Clinic, and David Zidar, MD, PhD, an interventional cardiologist and immunologist, introduce Cleveland Clinic’s Cardioimmunology Center, a new initiative focused on the intersection of immune pathways and cardiovascular disease. They discuss how immune system activity can influence heart health and discuss innovative approaches to identifying and managing cardiovascular risk through immunologic biomarkers. Looking to refer a...
Lee Kirksey, MD, Aravinda Nanjundappa, MBBS, MD, and G. Jay Bishop, MD, discuss a multidisciplinary approach to peripheral artery disease (PAD) management. They explore evidence-based strategies including early detection, optimal medical therapy, supervised exercise programs and advanced endovascular and surgical interventions, emphasizing team-based care and longitudinal follow-up for improved outcomes. Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri.,...
Allan Klein, MD, and Tom Kai Ming Wang, MBChB, discuss the 2025 ACC Concise Clinical Guidance on pericardial disease. They explore updated diagnostic criteria, the role of multimodality imaging and a shift toward IL-1 blockers for recurrent pericarditis. Learn practical strategies to optimize patient outcomes and avoid misdiagnosis or undertreatment, along with insights on surgical options and emerging clinical trials. Read about the new guidance. https://consultqd.clevelandclinic.org/resour...
Lars Svensson, MD, PhD, and Xiaoying Lou, MD, share a deep dive into valve-sparing aortic root surgery, an advanced technique that preserves the patient’s native valve while treating aortic aneurysms. Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.
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